&gt; these experiences -- which have an internal consistency -- seem to be inexplicably independent of culture, background or time<p>You&#x27;ve repeated this point in your other comments.  Why would these experiences not simply be a result of the interactions between this chemical and typical human physiology?  Alcohol has predictable effects when consumed -- I&#x27;m sure ancient Egyptians had equally impaired motor control as 21st century Australians.  Why would DMT be any different?