At first glance I&#x27;m not super into this... this seems like a bunch of opaque, hard-to-use utilities wrapped around already opaque, hard-to-use utilities (like GATK). What am I getting for my effort? I&#x27;d rather just use the low-level tool directly.<p>This seems more a way to pipe people into using Google Cloud Services for storing data than it seems a useful way to do bioinformatics. As with most of these cloud-genomics things, it&#x27;s not useful to have canned analyses that I can&#x27;t extend (for example, I am so far from giving a shit about transition&#x2F;transversion ratios and would never think to store that information in my variant table) What&#x27;s the big plus?