There would be better ways to spend your time than TAOCP.<p>If you want to scratch that itch, a better way would be Cormen, Leiserson, Rivest, and Stein&#x27;s <i>Intro to Algorithms</i> (<a href="https:&#x2F;&#x2F;mitpress.mit.edu&#x2F;books&#x2F;introduction-algorithms" rel="nofollow">https:&#x2F;&#x2F;mitpress.mit.edu&#x2F;books&#x2F;introduction-algorithms</a>).<p>I&#x27;m not aware of such a universal reference for the interaction between algorithms and architecture (&quot;...pipeline stalls, cache performance, ...&quot;).<p>Until that day comes...TAOCP sure looks nice on the bookshelf.