I don&#x27;t think using a placebo is sufficient in a study like this.<p>I&#x27;d like to see another psychedelic used as a control, not just a placebo.  Subjects are going to &quot;know&quot; when they&#x27;ve received psilocybin and then they&#x27;re going to be likely to &quot;perform&quot; better when evaluated for depression.<p>At least that would be my hypothesis.