This is a good overview of the research work and personality of Dr. Ioannidis. He looks forward to improvements in the process of science, as this interview transcript reports:<p>&quot;Q: Are you optimistic or pessimistic about the direction science is going in?<p>&quot;John Ioannidis: I am optimistic. I think that science is making progress. There’s no doubt about that. It’s just an issue of how much and how quickly.&quot;<p>Not mentioned in the article kindly submitted here, but likely to be of interest to many readers of Hacker News, is the site PubPeer[1] where you can search by topic for discussions among researchers (some named, some anonymous) about scientific papers that may have problems. Some papers have been retracted after PubPeer discussion revealed problems with the underlying data for study results.<p>[1] <a href="https:&#x2F;&#x2F;pubpeer.com&#x2F;" rel="nofollow">https:&#x2F;&#x2F;pubpeer.com&#x2F;</a><p><a href="http:&#x2F;&#x2F;retractionwatch.com&#x2F;2015&#x2F;08&#x2F;31&#x2F;pubpeer-founders-reveal-themselves-create-foundation&#x2F;" rel="nofollow">http:&#x2F;&#x2F;retractionwatch.com&#x2F;2015&#x2F;08&#x2F;31&#x2F;pubpeer-founders-revea...</a>