I agree the API is at this point is rather limited and it is difficult to use it in a way that would conveniently or efficiently replace any part of a genomic pipeline.<p>But I think google is onto something. If they manage to deconstruct BAM files and store them in &quot;format-free&quot; way that will allow search, aggregation, and computation&#x2F;reasoning across hundreds of thousands of patients&#x2F;samples it may accommodate the next big wave of personal genomics data.