Am not sure what part of your post contradicts what I wrote.<p>&gt;In some cases, chronic ketamine use has been associated 
&gt;In several reported severe cases<p>Chronic &#x2F; addiction levels yes. Not recreational levels. As I put<p>As to ketamine and bladder problems. I used to be involved with the UK free party scene which had serious problems with ketamine in the early 2000s ( up until the supply shortage caused by the Indian clampdown a few years ago), before it was well known about the addiction &#x2F; health problems it could cause (although issues were known, but it wasn&#x27;t generally well known beyond a few knowledgeable people).<p>You would often hear that ketamine had no comedown, had no side effects. Users would start out being weekend users, then progress to daily, sniffing between 3-7 grams a day, all day - everyday. Then gradually you started hearing about stomach cramps, difficulty going to the toilet, thinking you had to go to the toilet every 10 minutes, having to urinate a jelly&#x2F;jello like bloody substance. Drs had no idea what was going on and were no help. But by this stage the addiction had them completely and the only way to stop the pain was to sniff more ketamine. Eventually it led to a girl having kidneys  and &#x2F; or bladder removed and slowly the public conscience about the dangers of ketamine was known.<p>However, of all the users I knew who kept it to only weekends, used ketamine for years with none of the above mentioned health problems. Anecdotally of course and I am sure there may be edge cases I am unaware of. But recreational use of ketamine does not cause bladder problems IME