I&#x27;m not sure why you think dander is an &quot;orphaned&quot; word. It has a known definition <a href="https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Dander" rel="nofollow">https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Dander</a> and I would presume &quot;get one&#x27;s dander up&quot; originally referred to the material an animal would shed when it gets angry and starts eg. flapping its wings.