I haven&#x27;t heard much about CRISPR-Cas9 in population studies&#x2F;experiments like this  - my understanding was that you need to insert the RNA. Since RNA is so unstable it is usually a &#x27;one shot&#x27; process transfecting cells with plasmids through infusion.<p>Is the proposed mechanism to release a virus with the appropriate RNA scaffolds in the wild?<p>This strikes me as extremely dangerous