I understand your position, as it&#x27;s one I held very strongly for a long time.<p>I also agree with your point about &quot;people reacting to things with the wrong emotions or the wrong intensity of emotion&quot;; understanding and addressing this has been fundamental to my own recovery.<p>What I&#x27;m disputing is the notion that there is a clear-cut distinction between &quot;exogenous&quot; and &quot;endogenous&quot; depression, and that one is &quot;totally unrelated&quot; to the other. Nothing in biology - or in and truly complex system - works like that.<p>That said, I&#x27;m not presuming to be able to change your mind, but more pointing out that the premise your position relies on - that one&#x27;s environment and one&#x27;s emotional response to their environment are completely independent - is neither an undisputed scientific fact nor true in my own experience or anyone else I&#x27;ve observed.