That would be a research subject in the mathematics of origami.<p>That field is fairly advanced (See for example <a href="http:&#x2F;&#x2F;www.langorigami.com&#x2F;science&#x2F;science.php" rel="nofollow">http:&#x2F;&#x2F;www.langorigami.com&#x2F;science&#x2F;science.php</a>), but I am not aware of people studying &#x27;boxes&#x27;.