Mice are ~30% similar genetically to humans, so a surprising amount of transfers. Rats are a bit more similar IIRC, but mice breed quicker so it&#x27;s easier to do bigger studies...<p>Source: Used to work in mouse research on addiction (alcohol, cocaine, nicotine, etc).<p>Edit: This link gives even more specifics on the similarity: <a href="https:&#x2F;&#x2F;www.genome.gov&#x2F;10001345" rel="nofollow">https:&#x2F;&#x2F;www.genome.gov&#x2F;10001345</a> -- 30% is probably accurate, but in terms of function, it&#x27;s even higher.