Just because I agree with most of your points and there seem to be some overexcited responses to the OP, here are two papers for anyone interested, summarising Aβ and tau [0] and some failures of Aβ therapies [1].<p>[0] <a href="http:&#x2F;&#x2F;www.nature.com&#x2F;nrn&#x2F;journal&#x2F;v12&#x2F;n2&#x2F;abs&#x2F;nrn2967.html" rel="nofollow">http:&#x2F;&#x2F;www.nature.com&#x2F;nrn&#x2F;journal&#x2F;v12&#x2F;n2&#x2F;abs&#x2F;nrn2967.html</a>
[1] <a href="http:&#x2F;&#x2F;www.nature.com&#x2F;nrneurol&#x2F;journal&#x2F;v9&#x2F;n12&#x2F;full&#x2F;nrneurol.2013.223.html" rel="nofollow">http:&#x2F;&#x2F;www.nature.com&#x2F;nrneurol&#x2F;journal&#x2F;v9&#x2F;n12&#x2F;full&#x2F;nrneurol....</a>