&gt; PCIe UARTs rather than USB, 2 GbE ports<p>I wonder what that overkill in speed is for. With serial ports you don&#x27;t need that much bandwidth (48 ports x 100 kBits = 4,8 MBit&#x2F;s, yes I know it&#x27;s 115200 but too drunk for math). You could even run that thing with a 10 MBit&#x2F;s LAN interface.<p>The only thing I understand is the PCIe stuff because USB latency can be problematic (especially on the Pi).