In regards your three points<p>0. CRISPR-Cas9 is an amazing simple system that has worked in every species tested. It really is not an issue to generate gene drivers for every species we want to go after.<p>1. How do you know it is ineffective? Do you understand how a gene driver system works? Arguments against attempting to control nature are rather weak - modern life is a successful attempt to control nature.<p>2. This is the genius of gene drivers. You let them go and they do all the work for you. We only have to release the driver into the mosquito population and it will do everything from there on its own.<p>This technology really is a massive game changer - we just have to be brave enough to use it.