Ketamine is an exciting experimental approach for depression (especially with suicidal thinking) and anhedonia.<p><a href="http:&#x2F;&#x2F;www.thelancet.com&#x2F;journals&#x2F;lanpsy&#x2F;article&#x2F;PIIS2215-0366(15)00392-2&#x2F;fulltext" rel="nofollow">http:&#x2F;&#x2F;www.thelancet.com&#x2F;journals&#x2F;lanpsy&#x2F;article&#x2F;PIIS2215-03...</a><p>Researchers seem to be using an infusion of 5 mg per kg of body weight.  That means you don&#x27;t give a bunch of pills to a patient, which in itself helps a bit to reduce risk.<p>There&#x27;s a bit of a web-based discussion here: <a href="https:&#x2F;&#x2F;www.youtube.com&#x2F;watch?v=5b6zrpd1trk" rel="nofollow">https:&#x2F;&#x2F;www.youtube.com&#x2F;watch?v=5b6zrpd1trk</a>