Mouse models are rapidly becoming obsolete as it&#x27;s becoming easier than ever to model entire, differentiated tissues  grown from red blood cell-derived adult stem cells.<p>It&#x27;s also now possible to do clinically-useful testing of targeted treatments using genetically-edited control tissue cultures against unedited tissue cultures.<p>The point is that it&#x27;s better to test something that is as close to the patient as possible, not guess with other species or even other people whom express genes differently.<p>FYI: making a new mouse models requires lots of chopping off heads of mice whom don&#x27;t possess the desired gene.  While transgenic, highly-edited living models might be nice, there&#x27;s probably a more humane&#x2F;simpler&#x2F;reproducible way to do the exact same thing.