You&#x27;re comparing the number across births in the UK to the number across the total population of Brazil.. There aren&#x27;t 190M births in Brazil every year but closer to 2.7M (birth rate of ~14&#x2F;1,000) -- only counting the known cases of microencephaly yields an occurrence of 89&#x2F;100,000 or about 90x as frequent as in the UK. Seems pretty substantial, no?