Not really. Side-effects aren&#x27;t to be observed in a vacuum.<p>We should be far more concerned about side-effects of a drug intended to treat acne or erectile dysfunction than for drugs targeting life destroyers such as cancer and Alzheimer&#x27;s.<p>At some threshold of disease viciousness, society (and the FDA) should relax substantially on the risk-aversion, because the patient is <i>already</i> facing the worst-case scenario.