Have you had trouble with any specific libraries? We&#x27;re using alpine-based images with statically-linked binaries and haven&#x27;t had any issues compiling third-party libs. One area you&#x27;re likely to run into trouble is RPC, but I only discovered that in messing about with something experimental.<p>The real problem with musl in these environments is its DNS behavior, particularly if you&#x27;re running on a platform like Kubernetes that uses DNS search domains for service discovery. Not hard to work around, but the workarounds are a bit, er, inelegant. See <a href="http:&#x2F;&#x2F;www.openwall.com&#x2F;lists&#x2F;musl&#x2F;2015&#x2F;09&#x2F;04&#x2F;4" rel="nofollow">http:&#x2F;&#x2F;www.openwall.com&#x2F;lists&#x2F;musl&#x2F;2015&#x2F;09&#x2F;04&#x2F;4</a> and <a href="https:&#x2F;&#x2F;github.com&#x2F;gliderlabs&#x2F;docker-alpine&#x2F;issues&#x2F;8" rel="nofollow">https:&#x2F;&#x2F;github.com&#x2F;gliderlabs&#x2F;docker-alpine&#x2F;issues&#x2F;8</a>