I&#x27;m just not sure what the advantage is. I don&#x27;t take alcohol, other than the occasional beer&#x2F;wine, as I don&#x27;t particularly like the effects. Same for smoking&#x2F;caffeine&#x2F;pot. I have much better experiences with real-life, such as flying planes, climbing mountains, etc. I understand LSD and ketamine are going to give a kind of the experience you can&#x27;t get in real-life, but screwing around with your brain to achieve it doesn&#x27;t really seem to be worth the risk IMO. I&#x27;ve managed to completely screw up my brain once in my life (severe suidical depression &#x2F; CFS) without any help from any mind-altering substances, so to be honest I&#x27;m not really sure it&#x27;s a good idea to be screwing around with your neurotransmitters like that. It&#x27;s like trying to make your zx81 do something cool by randomly poking memory locations or wobbling the 16k RAM pack.