Prison is not exactly the most healthy environment in which to take psychedelics.<p>Set and setting are critically important.  Psychedelic states tend to make one highly vulnerable and suggestible.  I would be surprised if taking them in prison did not have some negative effects.<p>The same goes for CIA experimentation, which was often done on unwitting subjects.<p>There are constructive and destructive ways to use these powerful tools.  Experiments on prisoners and CIA mind-control experiments would qualify as the latter.