I am a programming neuroscientist who studies Alzheimer&#x27;s, and I would like to say that, while it is not entirely clear whether or not N-acetylcysteine will prove fruitful as a therapeutic for Alzheimer&#x27;s, PA&#x2F;tylenol is not the same thing as N-acetylcysteine, so the NSAID link is irrelevant in that regards. The link between these two is that N-acetylcysteine is used as a treatment for overdose of PA - because of a metabolite which is produced following high consumption of PA (NAPQI). Importantly, this link does not indicate that they have inversely correlated mechanisms of action under normal circumstances. PA may not be worth exploring further, but the understanding of N-acetylcysteine is still worth exploring. <i>Note</i> I do not study this myself, just putting in my two cents.