&gt; &quot;Responsible&quot; is a pretty strong word (and not supported by the research).<p>I think &quot;seems, in fact, to be responsible&quot; its a pretty fair simple characterization of the conclusion of the linked article, that Alzheimers is a human-created condition with PA has its principal risk factor.<p>(&quot;is responsible&quot; would be stronger than is supported, but that&#x27;s not what I said.)