Your own source contradicts that last claim.<p>&quot;those that exercise at least 4 hours per week are as healthy as those that sit fewer than 4 hours&quot;<p>Readable copy of the paper on which that article is based:<p><a href="http:&#x2F;&#x2F;www.researchgate.net&#x2F;publication&#x2F;46255258_Occupational_Sitting_and_Health_Risks" rel="nofollow">http:&#x2F;&#x2F;www.researchgate.net&#x2F;publication&#x2F;46255258_Occupationa...</a><p>The authors found a &quot;convincing&quot; correlation between sedentary behavior and health risks only for for cancer and CVD (see the &quot;discussion&quot; section).  They specifically looked for such a correlation to insulin resistance, but didn&#x27;t find any; they didn&#x27;t look for other symptoms that have been mentioned (e.g. cataracts) at all.<p>It&#x27;s not at all clear that weightlessness is the same as sitting at a desk in terms of the conditions we&#x27;re talking about, but there <i>is</i> evidence that their rigorous exercise programs should counteract any such effects anyway.  I&#x27;m not saying your theory is invalid, but you&#x27;ve done anything but provide evidence for it.  It&#x27;s certainly not the kind of &quot;slam dunk&quot; that would have justified your haughty dismissal of the OP.