&gt; What do you mean by non-linear?<p>I mean in the mathematical sense [1], if modifying a piece of DNA can still produce unpredictable results then I wouldn&#x27;t really feel we should claim that we understand how the whole process works.<p>[1] <a href="https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Nonlinear_system" rel="nofollow">https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Nonlinear_system</a>