Nobody said it was hard to read. The comic you&#x27;re replying to certainly didn&#x27;t say that.<p>I disagree that you could look at Google&#x27;s source code and know much about the data center. You would have to have a lot more knowledge about infrastructure which is completely hidden from you. And that&#x27;s about where we are with proteins. We can figure out the protein, and then try to simulate what it would do, but it&#x27;s not easy or straight forward.<p>So your analogy with Google source code would be like, you could simulate what a data center might be like, but you&#x27;re just guessing and could be way off.<p>I think the point of the comic is that if you look at Google source code, it&#x27;s NOT straight forward to understand. You can read it, sure. Anyone can read an operating system worth of assembly, too. But knowing what it does, that&#x27;s a hard problem (without running it). And that Google&#x27;s code is only a few years of optimization by people trying to keep the code comprehensible instead of billions of years of optimization with no care for readability or organization.