It isn&#x27;t possible to do a &quot;full&quot; reset without antibiotics (and even then it isn&#x27;t 100% complete).  The next best thing you can do is fasting.  Fasting greatly restricts the food supply to the microbes in your gut (gut mucus production still feeds them to a degree), causing a fairly large die-off and shift in bacterial equilibrium.  Anywhere between 4 and 7 days is a good target, and it doesn&#x27;t have to be a strict fast, a little fruit juice or tea is fine.