I&#x27;m sorry if you took offence at my use of the idiom &quot;all in the mind&quot; - its intended meaning is &quot;imagined&quot; rather than &quot;psychiatric&quot;. I am not implying psychiatric illnesses are not real.<p>Regarding the PACE trail; I was referring to the trail conducted in the UK. About 73% of people with ME do not gain any benefit in symptom relief when CBT is used as a primary intervention.<p><a href="http:&#x2F;&#x2F;www.meassociation.org.uk&#x2F;2015&#x2F;10&#x2F;press-release-me-association-pace-trial-treatments-offer-hope-for-chronic-fatigue-syndrome-28-october-2015&#x2F;" rel="nofollow">http:&#x2F;&#x2F;www.meassociation.org.uk&#x2F;2015&#x2F;10&#x2F;press-release-me-ass...</a>