One area that&#x27;s ripe for disruption is Next Generation Sequencing (a high throughput derivative of Sanger sequencing)<p>Illumina produces devices called sequencers, which are glorified microfluidics + imaging devices, which uses base pair chemistry to build the dna complementary strands of single stranded dna fragments one base by one using special dna bases that have washable fluorescent die and are blocking (so that the complementary strand grows by one base). Once the correct dna base is stuck to the single strands on the glass device, a picture of the glass device is taken by shining laser and using a CCD imager. The Nature of DNA makes sure that the correct complementary base gets stuck. 4 TIFF files are generated with billions of tiny dots one for each base A,C,G and T. The fluorescent die is washed, and the last added ddna base is deblocked and the cycle repeats.  The whole software suite (image processing of TIFF files) and hardware specs (fluid chemistry, etc) is unfortunately closed source :(