&gt;&quot;Both experiment and calculation seem to indicate that water confined by solid walls to tiny regions of space, whose size is comparable to that of a few hundred molecules, begins to exhibit quantum mechanical effects, including delocalization and quantum coherence.&quot;<p>Sounds like a possible source of random entropy for crypto :-) I did the Wolfram Alpha query[1] and it turns out that 100 molecules of water has a volume of 2.992 yL (yoctoliters, 10^-24 L). I didn&#x27;t think we were up to yocto-technology yet! The paper that seems to describe this is called &quot;Evidence of a new quantum state of nano-confined water&quot;[2] so I have a feeling that &quot;a few hundred molecules&quot; may be a few orders of magnitude out.<p>From the paper:<p>&quot;We find that in water confined on scales of 20˚A, this wave function responds to the
details of the confinement, corresponds to a strongly anharmonic local potential, shows evidence
in some cases of coherent delocalization in double wells, and involves changes in zero point kinetic
energy of the protons from -40 to +120 meV difference from that of bulk water at room temperature.
This behavior appears to be a generic feature of nanoscale confinement.&quot;<p>It&#x27;s a really interesting paper. (although I had to do a lot of Wikipedia searches on certain terminology!)<p>[1]: <a href="http:&#x2F;&#x2F;www.wolframalpha.com&#x2F;input&#x2F;?i=volume+of+100+molecules+of+water" rel="nofollow">http:&#x2F;&#x2F;www.wolframalpha.com&#x2F;input&#x2F;?i=volume+of+100+molecules...</a><p>[2]: <a href="http:&#x2F;&#x2F;arxiv.org&#x2F;abs&#x2F;1101.4994" rel="nofollow">http:&#x2F;&#x2F;arxiv.org&#x2F;abs&#x2F;1101.4994</a>