I picked contraception and melatonin on purpose because they illustrate two ways to get around Algernon&#x27;s argument, which is the justification behind the &quot;no free lunch&quot; heuristic in nootropics.<p><a href="http:&#x2F;&#x2F;www.gwern.net&#x2F;Drug%20heuristics" rel="nofollow">http:&#x2F;&#x2F;www.gwern.net&#x2F;Drug%20heuristics</a>