You said SF, not Silicon Valley.<p>Degree is not relevant, no one in SV cares.  There are plenty of people that don&#x27;t have college degrees that have very good jobs.  All that matters is your skill and competence.<p>You are in an awkward position.  You know Javascript, but you don&#x27;t know front end.  There aren&#x27;t very many purely backend positions that require only Javascript&#x2F;Node.  They probably expect a complete fullstack knowledge, so not knowing front end will hurt you, and not knowing a more back-end language like Python, Java, etc will also hurt you.<p>Keep interviewing, but learn a new language, like Python or Java, and try to get some experience in it, through open source projects, freelancing, etc.