Evidence?<p>As far as I could ever tell there was only one widely reported (<i>before</i> prohibition), and it was misreported by the press. The substance that killed that guy was methadone.<p>--edit-- I see from a quick scan of wikipedia that there were a very few deaths<p>The only one definitely cause by mephedrone and pre-ban I can see was &quot;The first death reported to be caused by mephedrone use was that of 46-year-old, John Sterling Smith, who had underlying health problems and repeatedly injected the drug&quot;<p>It&#x27;s not exactly a surprise at that point.