Not at all. It is an internal implementation detail that, in almost all relevant topologies, ZeroMQ can do with just one socket connection but NATS needs two. Furthermore, in LAN pub&#x2F;sub topologies, ZeroMQ can do with just one copy of the message on the outgoing wire + the occasional retransmit (letting the switch handle the broadcast&#x2F;multicast) whereas NATS requires a copy for every subscriber.<p>&gt; Obviously the latency of going over the wire once is going to be lower than going over the wire twice.<p>Latencywise, and all things being optimal, yes. But not all things are optimal.<p>Throughputwise, and all things being optimal, there shouldn&#x27;t be any difference. But there is a huge one on both receive and transmit.<p>NATS and ZeroMQ are obviously not equivalent, but I maintain that this is an apples-to-apples proper and useful comparison, even without the forwarding device.