It&#x27;s a feel good story but the path do a drug is anything but linear like this portrays. The vast majority of compounds, even when there is a molecule targeting it; fail in Phase I, II, or III trials; or fail to improve upon existing therapies. The truth is, there are about ~5K genes in yeast, and about ~8K yeast geneticists. A lot of stuff that works in the lab doesn&#x27;t work on actual people or the drug has side effects due to lack of specificity. Selection bias will make a bunch of them look like they&#x27;re ahead of the curve.   A bit like star mutual fund managers.