Maybe but people look at epidemiologic patterns (i.e. the whole point of the World of Warcraft Zombie paper earlier), and Parkinson&#x27;s disease doesn&#x27;t really seem to show any of the typical patterns.   It&#x27;s a really difficult problem, and also the reportability of linked cases may be an issue, as if you &quot;get&quot; parkinson&#x27;s, you don&#x27;t really know until 10 years or more after the fact...<p>There may be something to whatever makes misfolded synucleins agregate, but at the last big international conference, there was a battle royale between the pro&#x27;s and the con&#x27;s of prionism, i.e. do synucleins exhibit the properties of the prions involved in CJD and other prion disease, vs. just being an example of a self aggregating protein.     The con&#x27;s won by a healthy margin