Ever tried it? I would not recommend it, especially with Xcode but generally for most OS X apps.<p>It&#x27;s fine for running multiple instances of the simulator if that&#x27;s all you need to do. You&#x27;ll be sorry if you try to actually work with code though. Settings will be overwritten, caches will be corrupted and some things won&#x27;t work. The problem is that OS X isn&#x27;t designed with this in mind at all and you&#x27;re actually working against that design when you do this.