Depression, like obesity, is acquired, habitual change due to environmental factors. Non fraudulent CBT (active traveling in a unfamilar environment as a simplest example) is enough to introduce persistent changes (that is why there are so many stories about profound changes people undergo after visiting the East - radical behavioral change will lead, through conditioning, to change in biochemistry - body is a dynamic, adaptive system).<p>There is, of course, no way to change one&#x27;s physical or mental conditions without introducing changes to habits, daily routines and environment.