Nothing more recent than this summary post from January - but read the comments, since a researcher with an alternate approach participated.<p><a href="https:&#x2F;&#x2F;www.fightaging.org&#x2F;archives&#x2F;2016&#x2F;01&#x2F;the-present-state-of-progress-towards-clearing-glucosepane-cross-links-a-contributing-cause-of-degenerative-aging&#x2F;" rel="nofollow">https:&#x2F;&#x2F;www.fightaging.org&#x2F;archives&#x2F;2016&#x2F;01&#x2F;the-present-stat...</a><p>Essentially the few people working on this are still looking for drug candidates, largely based on mining the bacterial world for suitable enzymes to use as a basis. They have bacteria that consume glucosepane, so that&#x27;s a starting point.