A few areas - Data, Analysis, and Reporting. I work in institutional real estate and we still heavily rely on legacy data providers (Costar and Brokerages), do most of our analysis in Excel, and Reporting in Word and Powerpoint. Financial instruments have been largely unchanged for the past 20 years, and perhaps new ways to fund debt and equity could be areas for change. By and large though, new ways to get data that is meaningful and ways to analyse it could be winners. Also, CRE has changed a lot in the last couple of years. First movers like VTS, Hightower, the crowdfunding companies, and even brokerage companies are starting to embrace technology beyond email and phone calls.