This is from 4 years ago (<a href="http:&#x2F;&#x2F;www.ncbi.nlm.nih.gov&#x2F;pmc&#x2F;articles&#x2F;PMC3471395&#x2F;" rel="nofollow">http:&#x2F;&#x2F;www.ncbi.nlm.nih.gov&#x2F;pmc&#x2F;articles&#x2F;PMC3471395&#x2F;</a>) and didn&#x27;t even involve 23andMe (way to go, 23andMe, you&#x27;ve sure been making good use of all that donated phenotype info...).<p>A more relevant link might be <a href="http:&#x2F;&#x2F;www.ncbi.nlm.nih.gov&#x2F;pmc&#x2F;articles&#x2F;PMC4650984&#x2F;" rel="nofollow">http:&#x2F;&#x2F;www.ncbi.nlm.nih.gov&#x2F;pmc&#x2F;articles&#x2F;PMC4650984&#x2F;</a> ; the GCTAs show that the common SNPs examined <i>do</i> explain a decent fraction, but it&#x27;s increasingly looking like rare variants and novel mutations may explain the rest.