Also FWIW the ClojureCLR blog has lots of interesting tidbits about some of the intricacies that directly address your question: <a href="http:&#x2F;&#x2F;clojureclr.blogspot.com&#x2F;" rel="nofollow">http:&#x2F;&#x2F;clojureclr.blogspot.com&#x2F;</a>