As someone who does quite a lot of image and signal processing the fact that their arrays are 1-based is a complete deal breaker. The first few years of my career I worked with Matlab and I hated 1-based arrays with a passion. I think I never encountered a situation where the Matlab way makes stuff easier, almost always the 0-based index is the more natural choice.<p>After I switched to Python&#x2F;C I can say that I never want to work with 1-index languages again.