&gt; With proper availability, opiates are very well tolerated.<p>This just is not true.  With proper availability people develop tolerance, and require higher doses.  That does becomes high enough to become dangerous, and so they need to change to a different, stronger opiate.  They develop a tolerance to that too.<p>Eventually they&#x27;re cycling through 2 or three different opiates (sometimes at the same time) at very high dose. <i>And their pain is not being managed</i>.<p>&gt; addicted to antipsychotics or insulin or antidepressants<p>No tolerance, no seeking, no preoccupation, no continuing to take them when you know they&#x27;re doing you harm -- those things are not addictive.