You could also say the next big tech startup will come from a random town around the world instead of Silicon Valley. But somehow the concentration of capital, expertise and opportunity in one place has a multiplier effect that makes Silicon Valley unreasonably effective at generating startups.<p>Similarly, you are more likely to &quot;hit the high notes&quot; in research by concentrating effort in a few places. The alternative is lots of duplicated efforts that each don&#x27;t quite achieve anything.<p>This applies especially to medical research where the barriers to getting meaningful clinical results are sky high.