My best mouse has to be the Microsoft Explorer. Smooth as ice. Sadly, the quality of optical sensors seems to be regressing.<p>I&#x27;ve recently been using the Razer Naga - the optical sensor comes <i>close</i> and it fits perfectly in my hand - I barely notice that it&#x27;s there. It&#x27;s worth a try if ergonomics is important to you. YMMV, my ergonometrics aren&#x27;t the same as yours.