Disassociatives have been used for a while in the treatment of opiate addiction, including the usage of higher doses of dextromethorphan to treat heroin addicts. To me it comes with little surprise that this could also be an effective treatment for depression, despite the fact that depression isn&#x27;t necessarily something that can just be treated away. I&#x27;ve personally done more than my fair share of recreational ketamine and it seemed to aid my coping with some major life issues I&#x27;ve had, though I suppose this could also be placebo. Regardless, I&#x27;m glad these types of studies are being done and hope to see some more concrete evidence of positive effect.