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What Is The Function Of Erythropoietin
Kidney failure: Erythropoietin is commonly used in people with anemia due to kidney failure. Other uses include anemia associatid with hiv, chemotherapy and some types of bone marrow diease. It may also be used pre-surgically in certain selected patients. It has also been used improperly as a performance enhancing agent in competative sports. ...Read moreSee 1 more doctor answer
Hypoxia: This is a very complex process. The simplest answer is: hypoxia (low oxygen tension, anemia) stimulates HIF production (hopoxia-inducible factor) which then stimulates epo release from the kidney. Another protein called VHL inhibits HIF action on epo (negative regulator). Mutation of VHL can cause excessive epo release, resulting in congenital erythrocytosis (a rare genetic disorder). ...Read more
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