Hyperbilirubinemia, more precisely hyperbilirubinemia due to the unconjugated fraction, may cause bilirubin to accumulate in the grey matter of the central nervous system, potentially causing irreversible neurological damage, leading to a condition known as kernicterus. Depending on the level of exposure, the effects range from unnoticeable to severe brain damage and even death. Newborns are especially vulnerable to hyperbilirubinemia-induced neurological damage, so must be carefully monitored for alterations in their serum bilirubin levels. Individuals with parenchymal liver disease who have impaired hemostasis may develop bleeding problems.
symptom of Thalassemia
symptom of Alpha-thalassemia
symptom of Vitamin B12 deficiency anemia
symptoms of Aplastic anemia
symptom of Congenital dyserythropoietic anemia
symptom of Scurvy
symptom of Atransferrinemia
symptom of Haemophilia