text: Pugs can suffer from necrotizing meningoencephalitis ( NME ) , also known as pug dog encephalitis ( PDE ) , an inflammation of the brain and meninges , that also occurs in other small-breed dogs , such as the Maltese and Chihuahua .
simplified: NME is an inflammation of the brain and meninges . It is also known as pug dog encephalitis ( PDE ) .