text: Charles is perhaps best known as the instigator of the unsuccessful Jacobite uprising of 1745 , where he led an insurrection which ended in defeat at the Battle of Culloden that effectively ended the Jacobite cause .
simplified: Charles is perhaps best known as the leading the unsuccessful Jacobite uprising of 1745 , where he led an rebellion which ended in a defeat at the Battle of Culloden that effectively ended the Jacobite cause .