english: We think this is why, to date, these kinds of drugs have failed in clinical trials -- not because the science wasn't sound, but because the people in these trials were already symptomatic.
non_english: We denken dat dit de reden is waarom  medicatie tot nu toe onsuccesvol was in klinische studies -- niet omdat de aanpak  van onvoldoende kwaliteit was, maar omdat de proefpersonen  reeds symptomatisch waren.