anchor: They create a culture in which you must fight against these conditions--even if it means risking serious side effects (the anti-fungal drugs for nails can damage the liver, Propecia's anti-testosterone action can decrease libido).
positive: A culture is created where fighting these conditions is made to seem important enough that even serious side effects don't keep people from taking the drugs.
negative: They create a culture where all conditions are acceptable and preferable to taking drugs with nasty side-effects.