anchor: The first warning that these drugs could pose health risks came a year ago, when the New England Journal of Medicine published an article by French researchers linking fen-phen to a deadly cardiac disease called primary pulmonary hypertension.
positive: Primary pulmonary hypertension has been linked to a drug called fen-phen.
negative: It has been known for nearly 3 years that there was a linkage between the use of fen-phen and cardiac disease.