anchor: Trials should be conducted starting with other or no opening questions, using other consumption questions such as those in AUDIT, using other screens such as TWEAK rather than CAGE, changing the sequence to CAGE or TWEAK followed by consumption questions, and checking BAC at the beginning or end of the protocol.
positive: It's suggested to use questions from those in AUDIT when conducting trials.
negative: CAGE screens are preferred over TWEAK when conducting this trial.