anchor: In 1543 Portuguese explorers reached Tanegashima Island, off southern Kyushu, followed over the next decade by Portuguese traders and Jesuit missionaries, headed by St Francis Xavier, who landed at Kagoshima in 1549.
positive: In 1543 Portuguese explorers landed at Tanegashima Island off Kyushu and were followed by missionaries and traders.
negative: In 1543 Portuguese explorers narrowly avoided landing at Japan and instead proceeded to India.