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The cause of itai-itai disease was determined to be cadmium poisoning in the drinking water from the Jinzugawa River basin. The source of cadmium was discovered to be from Mitsui Mining and Smelting Company. Mitsui Mining began to discharge cadmium into the Jinzugawa River in 1910.
Viruses, bacteria and mycoplasma, a type of small-cell bacteria, are implicated in autoimmune diseases. Often a bout of illness with a virus such as the Epstein-Barr virus triggers the onset of an autoimmune disease.Toxic Metal Exposure. An estimated twenty-five percent of us have some form of heavy metal poisoning.his means that if you have a family member with an autoimmune disease, you are at an increased risk of developing an autoimmune condition as well. And it does not have to be the same disease-one relative may have autoimmune thyroid disease, another multiple sclerosis, and another inflammatory bowel disease.