Johann Sebastian Bach born, 21 March, at Eisenach. Youngest child of Johann Ambrosius Bach, town and court musician, and his wife Maria Elisabetha, nÃ©e LÃ¤mmerhirt. Baptised, 23 March.
â¢Parkinson disease 11 (PARK11): Type 11 Parkinson disease is linked to a genetic mutation on chromosome 2q21.2. Parkinson's disease is a chronic, progressive, degenerative brain disorder characterized by tremors, muscle rigidity and slowed movements.
For years, scientists thought there was no genetic basis for Parkinson's. Then, in 1997, researchers at the National Institutes of Health discovered that mutations in a gene called SNCA (which encodes alpha-synuclein) were common in several families with a high prevalence of Parkinson's.