The Treaty of Kanagawa was an 1854 agreement between the United States of America and the government of Japan. The treaty, which was essentially imposed on the Japanese by threat of force, opened two Japanese ports for trade with American ships. The treaty was the first modern treaty Japan had with a western nation.
Platelets have no cell nucleus: they are fragments of cytoplasm that are derived from the megakaryocytes of the bone marrow, and then enter the circulation. These unactivated platelets are biconvex discoid (lens-shaped) structures, 2â3 Âµm in greatest diameter.
Fibrin are platelets that have changed in shape that form a net-like substance in which blood clots are formed by the entrapment of red and white cells and platelets. When they are formed in the blood when there is no injury there is an imminent danger of a blood clot that can cause a heart attack or stroke.