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Guanfacine Description. Guanfacine hydrochloride is a centrally acting antihypertensive with Î±2-adrenoceptor agonist properties in tablet form for oral administration. The chemical name of Guanfacine hydrochloride is N-Amidino-2-(2,6-dichlorophenyl) acetamide monohydrochloride and its molecular weight is 282.55.
Uses. This medication is used alone or with other medications to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Guanfacine acts in the brain. It decreases certain nerve signals from the brain to the blood vessels and the heart. This causes the blood vessels to relax so that blood can flow more easily and also slows the heart rate. These effects help to lower blood pressure.