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RH isoimmunization, also referred to as erythroblastosis fetalis is an incompatibility between an infantâs blood and the blood type of the mother.
In 1968, a process of medical intervention was invented and a product called RhoGAM or (Brand Rho(D) Immune Globulin (Human), became FDA approved and available for use. When an Rh-negative mother is given an injection of RhoGAM, it protects her immune system from being exposed to the Rh-positive blood. RhoGAM is usually administered twice during your pregnancy, if you choose to get it, once at 28 weeks and again within 72 hours of delivery. RhoGAM is a human blood/plasma product.