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âIf you have a first-degree relative with colon cancer, exams should start between ages 35 and 40,â says Fuchs. Colonoscopy is the most reliable test, because doctors can visually study the entire colon and rectum, Fuchs says.
Given that the average age for colon cancer diagnosis is 70, if someone were treated for the cancer at that age, then had a normal follow-up colonoscopy at age 75, another test at age 80 would be classified as too soon by the University of Texas study, Rex notes.