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Macrovascular disease: Disease of the large blood vessels, including the coronary arteries, the aorta, and the sizable arteries in the brain and in the limbs. Macrovascular disease is by contrast to microvascular disease.
Cerebrovascular refers to blood flow within the brain. Cerebrovascular disease includes all disorders in which an area of the brain is temporarily or permanently affected by bleeding or lack of blood flow. Cerebrovascular diseases included stroke, carotid stenosis, vertebral stenosis and intracranial stenosis, aneurysms and vascular malformations.