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Quick Answer. According to Good Housekeeping, brands of toilet paper that dissolve especially quickly include Scott 1000 one-ply, Target Up & Up two-ply, Seventh Generation two-ply, Scott Naturals two-ply and White Cloud Ultra three-ply. Contrary to expectations, one-ply toilet paper did not dissolve fastest in Good Housekeeping's tests, as of 2014.
Toilet paper took its next leap forward in 1890, when two brothers named Clarence and E. Irvin Scott popularized the concept of toilet paper on a roll. The Scotts' brand became more successful than Gayetty's medicated wipes, in part because they built a steady trade selling toilet paper to hotels and drugstores.