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Macrovascular disease: Disease of the large blood vessels, including the coronary arteries, the aorta, and the sizable arteries in the brain and in the limbs. Macrovascular disease is by contrast to microvascular disease.
10 hilariously insightful foreign words. Microvascular disease is a pathology that involves the small blood vessels in the body. This condition can manifest in a number of ways in different areas of the body. Treatment options depend on the underlying cause and how far the disease has progressed.ymptoms of microvascular disease may include numbness in the extremities. People with high blood pressure may be susceptible to developing microvascular disease. People with diabetes may be susceptible to developing microvascular disease. Heavy smokers are at special risk for developing microvascular disease.