It has been shown recently in China that arsenic trioxide (As2O3) is a very effective treatment for acute promyelocytic leukemia (APL).2) As2O3 does not influence bax, bcl-x, c-myc, and p53 gene expression, but downregulates bcl-2 gene expression at both mRNA and protein levels. (3) As2O3 induces a significant modulation of the PML staining pattern in NB4 cells and HL-60 cells.
What are the possible side effects of oseltamivir (Tamiflu)? Stop using oseltamivir and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat; a red and blistering or peeling skin rash.
Tamiflu Actions. Tamiflu acts by reducing the number of cells in your body that are affected by the influenza virus. It does this by binding to a coating, called neuraminidase, that's found on the surface of the virus. Neuraminidase allows the virus to penetrate healthy cells, where it can then produce more copies of the virus.