Johann Sebastian Bach born, 21 March, at Eisenach. Youngest child of Johann Ambrosius Bach, town and court musician, and his wife Maria Elisabetha, nÃ©e LÃ¤mmerhirt. Baptised, 23 March.
â¢Parkinson disease 11 (PARK11): Type 11 Parkinson disease is linked to a genetic mutation on chromosome 2q21.2. Parkinson's disease is a chronic, progressive, degenerative brain disorder characterized by tremors, muscle rigidity and slowed movements.
Parkinson's disease is a degenerative disease of the central nervous system resulting from depletion of dopamine-producing cells in a region of the brain called the substantia nigra. A variety of genetic and environmental factors underlie this loss of brain cells.