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âIf you have a first-degree relative with colon cancer, exams should start between ages 35 and 40,â says Fuchs. Colonoscopy is the most reliable test, because doctors can visually study the entire colon and rectum, Fuchs says.
But the most important thing is to get tested, no matter which test you choose. Starting at age 50, men and women at average risk for developing colorectal cancer should use one of the screening tests below: Tests that find polyps and cancer. Colonoscopy every 10 years; CT colonography (virtual colonoscopy) every 5 years*