To test directly the influence of nucleosome location on the ability of Dam methyltransferase to modify GATC sites in chromatin, we analyzed minichromosomes containing precisely positioned nucleosomes in dam-expressing yeast strains. Levels of methylation at individual GATC sites were rigorously quantified by an oligonucleotide-probing procedure.
Complete junior drum sets typically start at around $300. This price includes stock cymbals and all the necessary hardware and stands. Drum thrones â what you sit on â may not be included, and can range in price from $30 up to $200. A drum kit in the $300 range is acceptable for a young, first-time player. These junior kits are traditionally three- or four-piece sets.
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