Genesis are an English rock band formed at Charterhouse School, Godalming, Surrey in 1967. The most commercially successful and long-lasting line-up includes keyboardist Tony Banks, bassist/guitarist Mike Rutherford and drummer/singer Phil Collins.
Tay-Sachs diseases causes a progressive deterioration of nerve cells and of mental and physical abilities that begins around six months of age. The disease occurs when harmful quantities of cell membrane components known as gangliosides accumulate in the brain 's nerve cells.
Tay-Sachs disease is caused by a mutation in the HEXA gene. A genetic mutation is a permanent alteration in the DNA sequence that makes up a gene. It causes one or more processes of the body to not work properly. A mutated HEXA gene results in the body not producing an enzyme called Hexosaminidase-A (Hex-A).ay-Sachs disease used to be most common in people of Ashkenazi Jewish descent. Most Jewish people in the UK are Ashkenazi Jews. It's thought that around 1 in 25 Ashkenazi Jewish people are carriers of the mutated gene that causes Tay-Sachs disease.