Generally, anisocoria is caused by impaired dilation (a sympathetic response) or impaired constriction (a parasympathetic response) of pupils. An injury or lesion in either pathway may result in changes in pupil size.
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Clomipramine (trademarked as Anafranil and Clofranil) is a tricyclic antidepressant (TCA).It was developed in the early 1960s by the Swiss drug manufacturer Geigy (now known as Novartis) and has been in clinical use worldwide ever since.It is the 3- chlorinated derivative of the earlier tricyclic, imipramine.lomipramine has a number of uses in medicine including in the treatment of: 1  Obsessiveâcompulsive disorder (OCD) which is its only U.S. FDA-labelled indication.