White blood cells also help in production, transportation and distribution of antibodies in order to build the bodyâs immune system. When acute infection occurs, the white blood cells produce colony-stimulating factor (CSF), which further stimulates the bone marrow to increase the production of the white blood cell.
A variety of lower back conditions may lead to sciatica. Most commonly, a lumbar herniated disc will cause sciatic nerve pain. Other common disorders that cause sciatic pain include lumbar degenerative disc disease, spondylolisthesis, spinal stenosis, or osteophytes and arthritis in the spine.
If this causes pain, or makes your pain worse, it is usually an indication that your pain is being caused by the sciatic nerve. Warning signs. Your GP will also ask you questions about your medical history and individual circumstances.