Owners or operators of places of business (also called establishments or facilities) that are involved in the production and distribution of medical devices intended for use in the United States (U.S.) are required to register annually with the FDA. This process is known as establishment registration (Title 21 CFR Part 807).
1 1400sâ1800s (The Renaissance) â Copper, iron, steel, and wood were the most common materials used for prosthetics during this period.  1863 â During the American Civil War, the U.S. started to see advancements in the field of prosthetics.
Materials that can be used for mannequins are Ethafoam, wool felt, acryl (Perspex), plaster bandage, Plastazote (polyethylene foam), resin, buckram and papier machÃ©. The materials that are used should be inert, easy to work with, and safe for the costume.