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Mar 13, '09. The headache comes because Morphine produces vasodilation. This is why we give Morphine for chest pain patients. The vasodilation is great to reduce constriction due to angina, but it causes headaches due to the vasodilation.
Morphine is the principle alkaloid in opium (derived from poppy  plants). It is the active substance released by the metabolism of  heroin (morphine diacetate) in the human â¦body.    Morphine is an opiate - narcotic pain reliever used to treat  moderate to severe pain. It can easily become an addictive drug and  is regulated in the US as a Schedule II prescription medication.