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âIf you have a first-degree relative with colon cancer, exams should start between ages 35 and 40,â says Fuchs. Colonoscopy is the most reliable test, because doctors can visually study the entire colon and rectum, Fuchs says.
A colonoscopy is an endoscopic evaluation of the colon, which may include a biopsy and/or removal of a lesion. An endoscopic colonoscopy on the large intestine or bowel is used to find ulcers, colon polyps, tumors, inflammation, and bleeding. The procedure is recommended for all adults starting at age 50 and then again every 10 years or so due to the higher risk of colorectal cancer in later years. The recommended frequency for a colonoscopy test also depends on various risk factors. Colon cancer is the 3rd most common cancer in the U.S.