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Macrovascular disease: Disease of the large blood vessels, including the coronary arteries, the aorta, and the sizable arteries in the brain and in the limbs. Macrovascular disease is by contrast to microvascular disease.
Cerebrovascular disease: Disease of the blood vessels and, especially, the arteries that supply the brain. Cerebrovascular disease is usually caused by atherosclerosis and can lead to a stroke.See also atherosclerosis, stroke.erebrovascular disease: Disease of the blood vessels and, especially, the arteries that supply the brain. Cerebrovascular disease is usually caused by atherosclerosis and can lead to a stroke.