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Hypochondriac comes ultimately from the Greek word hypokhondria, which literally means âunder the cartilage (of the breastbone).â In the late 16th century, when hypochondriac first entered the English language, it referred to the upper abdomen. The upper abdomen, it turns out, was thought to be the seat of melancholy at a time when the now-outdated medical theory of the four humors (blood, phlegm, yellow bile [choler], and black bile [melancholy]) was accepted as a basis for legitimate health practice.
The left hypochondriac region contains the stomach, the top of the left lobe of the liver, the left kidney, the spleen, the tail of the pancreas and parts of the small intestine, the transverse colon and the descending colon.