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A xanthoma (pl. xanthomas or xanthomata) (condition: xanthomatosis), from Greek xanthos, Î¾Î±Î½Î¸Î¿Ï, yellow, is a deposition of yellowish cholesterol-rich material that can appear anywhere in the body in various disease states. xanthelasma is a sharply demarcated yellowish collection of cholesterol underneath the skin, usually on or around the eyelids. Strictly, a xanthelasma is a distinct condition, only being called a xanthoma when becoming larger and nodular, assuming tumorous proportions.
They may appear as small yellow bumps or as flat, wide plaques on your elbows, knees, hands, feet, or buttocks. A type of xanthoma called xanthelasma palpebra appears on the eyelids. These yellow, fat deposits can potentially be signs of heart disease because they may indicate high levels of fats in the blood.