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Macrovascular disease: Disease of the large blood vessels, including the coronary arteries, the aorta, and the sizable arteries in the brain and in the limbs. Macrovascular disease is by contrast to microvascular disease.
Microvascular angina (MVA) is defined as angina pectoris caused by abnormalities of small coronary arteries. In itsmost typical presentation, MVA is characterized by angina attacks mainly caused by effort, evidence of myocardial ischemia on non-invasive stress tests, but normal coronary arteries at angiography. CLOSE WINDOW ]. Figure 1. Definition and classification of microvascular angina (MVA). In patients with sufficiently typical chest pain and normal coronary arteries, MVA is diagnosed after careful exclusion of other (cardiac and non-cardiac) causes.