Drug therapy is warranted for many dogs with liver disease. Glucocorticoids (âsteroidsâ) have been used to prolong survival times in dogs with liver disease due to their anti-inflammatory and immunosuppressive properties, although their use and appropriate dosage protocols are somewhat controversial.
chiasma. pl. chiasmata [L., Gr.] chiasm; in genetics, the points at which members of a chromosome pair are in contact during the prophase of meiosis and because of which recombination, or crossing over, occurs on separation.
During the diplotene stage: Within each tetrad, each pair of sister chromatids begins to separate. However, one or more ares remain in contact where chromatids are intertwined. Each such area, called a chiasma (pl. chiasmata) is thought to represent a point where nonsister chromatids have undergone crossing over.