The progression of the war demonstrated the South's disadvantage in engineering expertise; of the initial 65 cadets who resigned from West Point to accept positions with the Confederate Army, only seven were placed in the Corps of Engineers.
In all instances where the use of Gleostine is considered for chemotherapy, the physician must evaluate the need and usefulness of the drug against the risks of toxic effects or adverse reactions. Most such adverse reactions are reversible if detected early.
Berberine is an alkaloid, which is a chemical compound found in several plants such as goldenseal. For centuries, this herb was used by a number of Native American tribes for medicinal purposes, including stomach ulcers and eye irritation. 2012 study using human subjects found that three 500 mg doses of berberine a day for 12 weeks was more effective in lowering cholesterol than ezetimibe. Ezetimibe is a statin that is commonly found in medications for high cholesterol. Unfortunately, some people are unable to tolerate the side effects of statins.