Johann Sebastian Bach born, 21 March, at Eisenach. Youngest child of Johann Ambrosius Bach, town and court musician, and his wife Maria Elisabetha, nÃ©e LÃ¤mmerhirt. Baptised, 23 March.
â¢Parkinson disease 11 (PARK11): Type 11 Parkinson disease is linked to a genetic mutation on chromosome 2q21.2. Parkinson's disease is a chronic, progressive, degenerative brain disorder characterized by tremors, muscle rigidity and slowed movements.
Parkinson's disease is caused by a loss of nerve cells in the part of the brain called the substantia nigra.Nerve cells in this part of the brain are responsible for producing a chemical called dopamine.t is not known why the loss of nerve cells associated with Parkinson's disease occurs, although research is ongoing to identify potential causes. Currently, it is believed that a combination of genetic changes and environmental factors may be responsible for the condition.