A low level of cortisol in the blood can be caused by: Problems that affect the adrenal glands directly, such as Addison's disease or a tuberculosis infection of the adrenal glands. Problems with the pituitary gland that affect the adrenal glands, such as cancer or a head injury.
Sometimes people with rheumatoid arthritis who are not also taking methotrexate get an injection every week. For those with Crohn's disease and ulcerative colitis, the usual initial dose of Humira is 160 mg on the first one or two days of treatment, followed two weeks later by 80 mg.Two weeks after that, you would probably start a maintenance dose of 40 mg every other week.umira is a type of medication called a tumor necrosis factor (TNF) blocker, or anti-TNF drug. TNF blockers help reduce inflammation and slow the progression of inflammatory conditions by targeting TNF, a substance produced by the immune system that causes inflammation in the body.
Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. Discontinue HUMIRA if a patient develops a serious infection or sepsis. Reported infections include: 1  Active tuberculosis (TB), including reactivation of latent TB. 2  Patients with TB have frequently presented with disseminated or extrapulmonary disease. 3  Test patients for latent TB before HUMIRA use and during therapy.