Genesis are an English rock band formed at Charterhouse School, Godalming, Surrey in 1967. The most commercially successful and long-lasting line-up includes keyboardist Tony Banks, bassist/guitarist Mike Rutherford and drummer/singer Phil Collins.
Tay-Sachs diseases causes a progressive deterioration of nerve cells and of mental and physical abilities that begins around six months of age. The disease occurs when harmful quantities of cell membrane components known as gangliosides accumulate in the brain 's nerve cells.
Mutations in the HEXA gene cause Tay-Sachs disease. The HEXA gene provides instructions for making part of an enzyme called beta-hexosaminidase A, which plays a critical role in the brain and spinal cord.ecause Tay-Sachs disease impairs the function of a lysosomal enzyme and involves the buildup of GM2 ganglioside, this condition is sometimes referred to as a lysosomal storage disorder or a GM2-gangliosidosis. Read more about the HEXA gene.