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Macrovascular disease: Disease of the large blood vessels, including the coronary arteries, the aorta, and the sizable arteries in the brain and in the limbs. Macrovascular disease is by contrast to microvascular disease.
A cerebrovascular accident is an interruption or disruption of blood flow to the brain. When blood flow to an area of the. brain stops, oxygen and nutrients cannot get to that area of the brain, and brain cells begin to die, resulting in. permanent damage. Types.