Indemnity â the insurance company indemnifies, or compensates, the insured in the case of certain losses only up to the insured's interest.
Downstream processing refers to the recovery and purification of biosynthetic products, particularly pharmaceuticals, from natural sources such as animal or plant tissue or fermentation broth, including the recycling of salvageable components and the proper treatment and disposal of waste.t is an essential step in the manufacture of pharmaceuticals such as antibiotics, hormones (e.g. insulin and human growth hormone), antibodies (e.g. infliximab and abciximab) and vaccines; antibodies and enzymes used in diagnostics; industrial enzymes; and natural fragrance and flavor compounds.
Rab proteins, like all the GTPases of the Ras family, function as molecular switchs. In the active GTP-bound form Rab protein recruits soluble factors to relay the GTPase signal to downstream effector system/proteins, which respond to a specific Rab and mediates at least one element of the downstream effects.embrane-bound Rab GTP is stabilized by the recruitment of cytosolic effector proteins and regulates the activity of a downstream v/t-SNARE complex [73] and [104] . Upon GTP hydrolysis of the Rab protein, mediated by a GTPase Activating Protein (GAP), the active Rab is converted back to the GDP-bound form.