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âIf you have a first-degree relative with colon cancer, exams should start between ages 35 and 40,â says Fuchs. Colonoscopy is the most reliable test, because doctors can visually study the entire colon and rectum, Fuchs says.
Normally a colon cancer can take from 7 to 10 years to develop from a polyp. That is why the recommendation for colonoscopy is every 10 years, unless there is a prior family history. However, with Lynch Syndrome (HNPCC) due to a genetic mutation a colon cancer can develop in as little as 1 to 2 years.