Johann Sebastian Bach born, 21 March, at Eisenach. Youngest child of Johann Ambrosius Bach, town and court musician, and his wife Maria Elisabetha, nÃ©e LÃ¤mmerhirt. Baptised, 23 March.
â¢Parkinson disease 11 (PARK11): Type 11 Parkinson disease is linked to a genetic mutation on chromosome 2q21.2. Parkinson's disease is a chronic, progressive, degenerative brain disorder characterized by tremors, muscle rigidity and slowed movements.
1 Mutations of the PARK2 gene are mostly found in individuals with juvenile Parkinson's disease. 2  Parkin normally helps cells break down and recycle proteins. 3  PARK7 (Parkinson's disease autosomal recessive, early onset 7): PARK7 mutations are found in early-onset Parkinson's disease. In brain cells of individuals with Parkinson's disease, this protein aggregates in clumps called Lewy bodies. 2  Mutations in the SNCA gene are found in early-onset Parkinson's disease. 3  PARK2 (Parkinson's disease autosomal recessive, juvenile 2): The PARK2 gene makes the protein parkin.