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Macrovascular disease: Disease of the large blood vessels, including the coronary arteries, the aorta, and the sizable arteries in the brain and in the limbs. Macrovascular disease is by contrast to microvascular disease.
More commonly known as a stroke, the cause of cerebrovascular disease is either a clot or blockage that cuts off blood flow to a part of the brain or a brain hemorrhage. Both cases cause damage or death to brain tissue that can cause paralysis, speech disorders, swallowing problems and immobility.