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RH isoimmunization, also referred to as erythroblastosis fetalis is an incompatibility between an infantâs blood and the blood type of the mother.
A potentially dangerous condition, called Rh Disease, can result when the mother is Rh negative and the baby is Rh positive. Similar to an autoimmune condition, Rh disease occurs when the Rh-negative mother's body detects Rh factor in the baby's blood and develops antibodies to protect itself.