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RH isoimmunization, also referred to as erythroblastosis fetalis is an incompatibility between an infantâs blood and the blood type of the mother.
Rh factor is an antigen, a substance which stimulates the production of antibodies to fight foreign invaders, such as viruses, bacteria and transplanted organs. A given individual either has the antigen already in their blood (they are Rh positive), or they don't (they are Rh negative).