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âIf you have a first-degree relative with colon cancer, exams should start between ages 35 and 40,â says Fuchs. Colonoscopy is the most reliable test, because doctors can visually study the entire colon and rectum, Fuchs says.
âWe recommend regular screening colonoscopies every 10 years because the vast majority of adenomas in the average patient grow slowly and pose no risk for at least 10 years. âTherefore a routine colonoscopy every 10 years will assure us that colon polyps can be detected and removed long before cancer develops.â. The 10-year guideline applies to people with average risk of colon cancer.