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A person should try clozapine for at least four to six weeks. Some symptoms, such as hallucinations, anxiety, paranoia, and bizarre behavior, should improve within that time; other symptoms may take longer. Additional improvements may be noticed over six to twelve months.here have been no confirmed cases of TD directly caused by clozapine alone, but patients should be regularly monitored for the development of TD. While agranulocytosis usually occurs most commonly within the first 4â6 months of treatment, you are at risk of this rare adverse effect for as long as you take clozapine.
Schizophrenia requires long-term treatment. Do not stop taking clozapine, even when you feel better. Only your healthcare provider can determine the length of clozapine treatment that is right for you. Missing doses of clozapine may increase your risk for a relapse in your symptoms.Do not stop taking clozapine or change your dose without talking to with your healthcare provider first. For clozapine to work properly, it should be taken everyday as ordered by your healthcare provider.issing doses of clozapine may increase your risk for a relapse in your symptoms. Do not stop taking clozapine or change your dose without talking to with your healthcare provider first. For clozapine to work properly, it should be taken everyday as ordered by your healthcare provider.