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Some of the possible common medical causes of Extremity pain may include: 1  Brachial plexus lesions. 2  Carpel tunnel syndrome. 3  Biceps tendonitis.  Raynauds 1  phenomenon. Sickle cell anemia.  Black widow spider 1  bites. Polyneuropathy.  Cat scratch 1  disease. Post herpetic neuralgia.  Erythema nodosum.
2 doctors agreed: Possibly your back: Extremity nerve compression problems, tendinits or knee problems could cause your symptoms. More likley the burning down the leg could be from sciatica. Sciatica is due to low back issues such as arthritis or disc herniation compressing the sciatic nerve/branches.