Medical Definition of metastatic. 1  1: of, relating to, or caused by metastasis cutaneous metastatic disease as the first sign of lung cancer metastatic carcinoma metastatic spread. 2  2: tending to metastasize metastatic cancer cells metastatic prostate cancer.
Acetylcholinesterase inhibitor (generally referred to as cholinesterase inhibitor): a chemical that binds to the enzyme, cholinesterase, and prevents it from breaking down the neurotransmitter, acetylcholine.
1 Describe how cholinesterase inhibitors, including organophosphorus compounds (e.g., pesticides, nerve agents) and carbamates block the ability of acetylcholinesterase to break down acetylcholine.reakdown of Acetylcholine (Optional Reading). They do this by occupying and blocking the site where the neurotransmitter, acetylcholine, attaches to the enzyme, acetylcholinesterase. If you are interested in the details at the chemical level, see the Optional Reading below.