White blood cells also help in production, transportation and distribution of antibodies in order to build the bodyâs immune system. When acute infection occurs, the white blood cells produce colony-stimulating factor (CSF), which further stimulates the bone marrow to increase the production of the white blood cell.
A variety of lower back conditions may lead to sciatica. Most commonly, a lumbar herniated disc will cause sciatic nerve pain. Other common disorders that cause sciatic pain include lumbar degenerative disc disease, spondylolisthesis, spinal stenosis, or osteophytes and arthritis in the spine.
The most common cause of sciatica is a bulging or ruptured disc (herniated disc) in the spine pressing against the nerve roots that lead to the sciatic nerve.ciatica is pain, tingling, or numbness produced by an irritation of the nerve roots that lead to the sciatic nerve.