Genesis are an English rock band formed at Charterhouse School, Godalming, Surrey in 1967. The most commercially successful and long-lasting line-up includes keyboardist Tony Banks, bassist/guitarist Mike Rutherford and drummer/singer Phil Collins.
Tay-Sachs diseases causes a progressive deterioration of nerve cells and of mental and physical abilities that begins around six months of age. The disease occurs when harmful quantities of cell membrane components known as gangliosides accumulate in the brain 's nerve cells.
Children with Tay-Sachs disease lack a vital enzyme, hexosaminidase A (Hex-A). Hex-A is needed for the body to break down a fatty waste substance found in brain cells.Without Hex-A, this substance accumulates abnormally and causes progressive damage until the nervous system can no longer sustain life.hen both parents are carriers, there is a 2 in 4 (50%) chance, with every pregnancy, of having a child who is a carrier. When only one parent is a carrier, there is no chance the child will have Tay-Sachs disease.