Sickle cell anemia is an inherited disorder that, in the U.S. affects mainly African-Americans and Hispanic Americans. Red blood cells become crescent-shaped because of a genetic defect. They break down rapidly, so oxygen does not get to the body's organs, causing anemia.
Definition of BOW. intransitive verb. 1. 2. : to bend the head, body, or knee in reverence, submission, or shame. 3. : to incline the head or body in salutation or assent or to acknowledge applause. 4. transitive verb. 1.
In the sense of a deformity, it is the pathological curving of the spine, where parts of the spinal column lose some or all of their lordotic profile. This causes a bowing of the back, seen as a slouching posture.