Corticosteroids are also used supportively to prevent nausea, often in combination with 5-HT3 antagonists (e.g. ondansetron). Typical undesired effects of glucocorticoids present quite uniformly as drug-induced Cushing's syndrome.
Common causes. A gas explosion occurs when the gas/air mixture reaches a critical value, then any spark, flame or heat source can ignite the mixture. The explosion is caused when the rapidly expanding, burning gas is confined and builds up pressure. As the pressure builds, something has to give, and in a home gas explosion it is usually the windows.
When detonation occurs the end-gas is under a very high amount of heat and pressure, cause spontaneous combustion, and as a result a pressure spike within the combustion chamber. This can be caused by a number of things including engine-timing, too much spark advance, lower octane fuels, and compression ratio.