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Nerve cells called motor neurons control the skeletal muscles. Each motor neuron controls several muscle cells in a group known as a motor unit. When a motor neuron receives a signal from the brain, it stimulates all of the muscles cells in its motor unit at the same time.
Axons of alpha motor neurons bifurcate in the spinal cord and innervate a special inhibitory interneuron called the Renshaw cell (Figure 2.7). This interneuron innervates and inhibits the very same motor neuron that caused it to fire. Thus, a motor neuron regulates its own activity by inhibiting itself when it fires.