Drug therapy is warranted for many dogs with liver disease. Glucocorticoids (âsteroidsâ) have been used to prolong survival times in dogs with liver disease due to their anti-inflammatory and immunosuppressive properties, although their use and appropriate dosage protocols are somewhat controversial.
chiasma. pl. chiasmata [L., Gr.] chiasm; in genetics, the points at which members of a chromosome pair are in contact during the prophase of meiosis and because of which recombination, or crossing over, occurs on separation.
Crossing Over. During meiosis, when homologous chromosomes are paired together, there are points along the chromosomes that make contact with the other pair. This point of contact is deemed the chiasmata, and can allow the exchange of genetic information between chromosomes. This further increases genetic variation.