Genesis are an English rock band formed at Charterhouse School, Godalming, Surrey in 1967. The most commercially successful and long-lasting line-up includes keyboardist Tony Banks, bassist/guitarist Mike Rutherford and drummer/singer Phil Collins.
Tay-Sachs diseases causes a progressive deterioration of nerve cells and of mental and physical abilities that begins around six months of age. The disease occurs when harmful quantities of cell membrane components known as gangliosides accumulate in the brain 's nerve cells.
Tay-Sachs disease. Tay-Sachs disease occurs due to mutations disrupting the function of an enzyme needed to break down specific lipids which then accumulate in tissues, particularly neurons that use this type of lipid for membranes and synapses.utosomal recessive inherited, Tay-Sachs disease is most common in families of Eastern European Jewish origin, where as many as 1 in 45 are carriers of the mutant gene compared to the general incidence of 1 in 300. This disease has actually been described in the Ashkenazi Jewish population as early as the 15 century.