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However, it is not the same as the annual marigold plant that is often grown in gardens. Calendula has high amounts of flavonoids, plant-based antioxidants that protect cells from being damaged by unstable molecules called free radicals. Calendula appears to fight inflammation, viruses, and bacteria.owever, it is not the same as the annual marigold plant that is often grown in gardens. Calendula has high amounts of flavonoids, plant-based antioxidants that protect cells from being damaged by unstable molecules called free radicals. Calendula appears to fight inflammation, viruses, and bacteria.
Calendula is a plant. The flower is used to make medicine. Calendula flower is used to prevent muscle spasms, start menstrual periods, and reduce fever. It is also used for treating sore throat and mouth, menstrual cramps, cancer, and stomach and duodenal ulcers. Early research suggests that applying a specific gel (Estromineral Gel, Rottapharm-Madaus) that contains calendula, Lactobacillus sporogenes, isoflavones, and lactic acid to the vagina for 4 weeks reduces symptoms of vaginal atrophy such as vaginal itching, burning, dryness, and pain during intercourse. 2  Leg ulcers.