MAPK/ERK pathway. The MAPK/ERK pathway (also known as the Ras-Raf-MEK-ERK pathway) is a chain of proteins in the cell that communicates a signal from a receptor on the surface of the cell to the DNA in the nucleus of the cell.
Acclimatization or acclimatisation (also called acclimation or acclimatation) is the process in which an individual organism adjusts to a change in its environment (such as a change in altitude, temperature, humidity, photoperiod, or pH), allowing it to maintain performance across a range of environmental conditions.
Below are a few basic guidelines for proper acclimatization. 1  If possible, don't fly or drive to high altitude. Start below 10,000 feet (3,048 meters) and walk up. 2  If you do fly or drive, do not over-exert yourself or move higher for the first 24 hours.