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The osteon is the primary structure that makes up the hard outer layer of bones, which is generally known as â cortical bone .â Cortical bone, or compact bone, is dense, mature bone found in vertebrates such as mammals, amphibians, reptiles, and birds. It is this dense hard layer that gives a person or animal strength.
Osteoblast, large cell responsible for the synthesis and mineralization of bone during both initial bone formation and later bone remodeling. Osteoblasts form a closely packed sheet on the surface of the bone, from which cellular processes extend through the developing bone. They arise from the differentiation of osteogenic cells in the periosteum, the tissue that covers the outer surface of the bone, and in the endosteum of the marrow cavity. This cell differentiation requires a regular supply of blood, without which cartilage-forming chondroblasts, rather than osteoblasts, are formed.