Many congenital brain defects cause minor neurological impairment. People with these types of congenital brain defects can grow to function independently. Other defects are so severe that they are fatal before or shortly after birth. Some cause significant disabilities.
I am looking into this for a friend as well. The pancreas deals with digestive juices and insulin. Have a look at your medications to see if they may have gastrointestinal effects. I can tell you that Tramadol does affect the production of enzymes in the intestine.
The pancreas is also critical to the production of insulin and glucagon, which regulate glucose levels in the blood. If the pancreas stops producing insulin, this leads to diabetes and a number of associated health issues. Other problems that concern the pancreas include pancreatic cancer.