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The mononuclear phagocyte system constitutes macrophage cells spread throughout the human body. The macrophages are long-lived cells that provide a major defense system against hostile elements through phagocytosis and subsequent intracellular destruction of the particle or cell.
A monocyte is a type of white blood cell that is produced by the bone marrow and helps to protect the body from foreign invaders, such as harmful bacteria and viruses. When there is a decreased number of monocytes in the blood, the body is more susceptible to illness.ome of the most common causes of a low monocyte count are illnesses that affect the bone marrow, such as HIV, rheumatoid arthritis, or lupus. A low monocyte count may be caused by a vitamin deficiency.