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What to do about a droopy brow or eyelid. The effect of the Botox will last about three to four months. That is a long time to go around looking droopy on one side, but there are some options available to improve the situation.
Botox isn't reversible once it's been injected, but it does wear off. Its effects begin within 48 hours and become noticeable within five to 10 days. However, the effects only last between three to five months, at which point you'd need to get another Botox treatment to keep the anti-wrinkle effects.