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Nephrotic syndrome is characterized by large proteinuria (>3.5 g per 1.73 m2 body surface area per day, or > 40 mg per square meter body surface area per hour in children), hypoalbuminemia (< 2,5 g/dl), hyperlipidaemia, and edema (which is generalized and also known as anasarca or dropsy) that begins in the face.
Low Blood Protein Levels. Protein maintains the proper balance of fluids between the tissues and the bloodstream. Fluid is taken from the blood and builds up in the tissue. There are other possible causes of proteinuria in nephrotic syndrome, so be sure to talk with your doctor about your medical history before you seek treatment.