Summary Summary. Acute intermittent porphyria (AIP) is one of the liver (hepatic) porphyrias. AIP is caused by low levels of porphobilinogen deaminase (PBGD), an enzyme also often called hydroxymethylbilane synthase.
Pyridine-N-oxide is the heterocyclic compound with the formula C 5 H 5 NO. This colourless, hygroscopic solid is the product of the oxidation of pyridine. It was originally prepared using peracids as the oxidising agent. The molecule is planar.yridine-N-oxide is the heterocyclic compound with the formula C 5 H 5 NO. This colourless, hygroscopic solid is the product of the oxidation of pyridine. It was originally prepared using peracids as the oxidising agent. The molecule is planar.
In pyridine the lone pair of the nitrogen is NOT localised in the aromatic ring. The nitrogen is sp2 therefore the lone is the plane of the ring and cannot achieve the lateral overlapping to be localised.And as the lone pair is not localised it is more basic (more available to perform nucleophilic attacks).n pyrrole, the delocalisation exits because the lone pair is conjugated to the pi bond (conjugation N-sigma-pi). Therefore this lone pair is less basic (available to perform nucleophilic attack). Pyridine is more basic than pyrrole and not only in water. Source(s):