Mitochondria are well-defined cytoplasmic organelles of the cell which take part in a variety of cellular metabolic functions. Survival of the cells requires energy to perform different functions.The mitochondria are important as the fact that these organelles supply all the necessary biological energy of the cell, and they obtain this energy by oxidizing the substrates of the Krebs cycle.unctions of Mitochondria. The most prominent function of mitochondria is to produce energy to the cell in the form of ATP through oxidative respiration process. It also regulates the metabolic activity of the cell.
Sinemet (carbidopa-levodopa) is a combination of an inhibitor of aromatic amino acid decarboxylation and an aromatic amino acid used to treat Parkinson symptoms such as muscle stiffness, tremors, spasms, and poor muscle control.
Dopamine Drugs and Possible Side Effects. Levodopa and the dopamine agonists (e.g., ropinirole, pramipexole, rotigotine), though proven to be very effective agents for managing RLS, may lead to the development of three common problems when used chronically: augmentation, compulsive behavior and sleepiness. With augmentation the brain becomes more and more dependent on these dopamine drugs. 2  The brain does not see âropiniroleâ or âpramipexoleâ, it see these drugs as just more dopamine in the system. 3  Essentially over time the brain, seeing all this extra dopamine, decides it does not need to make as much.