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nodule - (mineralogy) a small rounded lump of mineral substance (usually harder than the surrounding rock or sediment) mineralogy - the branch of geology that studies minerals: their structure and properties and the ways of distinguishing them.
From Wikipedia, the free encyclopedia. A rheumatoid nodule is a local swelling or tissue lump, usually rather firm to touch, like an unripe fruit, which occurs almost exclusively in association with rheumatoid arthritis. Very rarely rheumatoid nodules occur as ' rheumatoid nodulosis ' in the absence of arthritis.