Conversely, serum resistin levels have been found to decline with decreased adiposity following medical treatment. Specifically, central obesity (waistline adipose tissue) seems to be the foremost region of adipose tissue contributing to rising levels of serum resistin.
Asphyxia or asphyxiation is a condition of severely deficient supply of oxygen to the body that arises from abnormal breathing. An example of asphyxia is choking. Asphyxia causes generalized hypoxia, which affects primarily the tissues and organs. There are many circumstances that can induce asphyxia, all of which are characterized by an inability of an individual to acquire sufficient oxygen through breathing for an extended period of time. Asphyxia can cause coma or death.
The disruption of cell metabolism in the tissues and the accumulation of toxic by-products result in patho-physiological consequences such as tissue necrosis, loss of consciousness and death. Forensic interest may then become a question of causation and how long the asphyxia lasted before death occurred. The latter may be important in cases where family members witnessed the suffering of the decedent. Lack of oxygen, either partial [hypoxia] or total [anoxia], can cause death.