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L-arginine has unpredictable effects on insulin and cholesterol-lowering agents. L-arginine may increase the effects of isosorbide mononitrate and other nitric oxide donors, such as glyceryl trinitrate and sodium nitroprusside. Side Effects. L-arginine has few reported adverse reactions. Nausea and diarrhea have been reported infrequently.
Benefits of L Arginine. The benefits of l-arginine include enhancing the function of the immune system, helping to detoxify the liver, and helping with fertility in men. L arginine also plays a vital role in the release of both insulin and growth hormones in the body.