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Causes of Human Skin Hyperpigmentation. The color of human skin is due primarily to the production of melanin by specialized cells in the skin called melanocytes. Melanin produced by these cells both absorbs and scatters UV radiation and thus protects skin from the damaging and mutagenic effects of the solar radiation.
The high level of melanin production by some melanocytes and not by others results in a blotchy, uneven freckle-like appearance of melanin on the surface of the skin. These areas of hyperpigmentation are called lentigenes and are commonly referred to as age spots or liver spots. Sun Exposure and Inflammation.