Actinic keratoses that develop on the lips are referred to as actinic cheilitis. The clinical appearance of an actinic keratosis is that of a small (several millimeters), red scaly papule or plaque, with induration and thickening of the epidermis.
1 Location: Ideally, the probe should be in close proximity to the forward or reverse primer, but should not overlap with a primer-binding site on the same strand. 2  Probes can be designed to bind to either strand of the target. 3  Melting temperature (Tm): Preferably, probes should have a Tm 6â8Â°C higher than the primers.
In chemistry, Q is the reaction quotient. It is used to determine which direction a reaction will proceed by comparing it to the equilibrium constant, Kc. At equilibrium, the forward reaction and the reverse reaction rates are equivalent. If Kc is greater than Q, then the reaction proceeds in the forward direction (to the right), creating more products.