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Nephrotic syndrome is characterized by large proteinuria (>3.5 g per 1.73 m2 body surface area per day, or > 40 mg per square meter body surface area per hour in children), hypoalbuminemia (< 2,5 g/dl), hyperlipidaemia, and edema (which is generalized and also known as anasarca or dropsy) that begins in the face.
Along with a high amount of protein in the urine, signs and symptoms of nephrotic syndrome include a low amount of albumin in the blood, higher than normal lipid levels in the blood, and swelling in the legs, feet, and ankles.