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Malignant hypertension is a serious condition caused by very high blood pressure. It can quickly cause serious damage to eyes, kidneys and brain. Some of the changes can be reversed by treatment but some permanent damage may occur. Malignant means bad or evil.
Malignant otitis externa progressing to skull base osteomyelitis is an aggressive infection of the temporal bone and skull base, associated with possible involvement of the facial nerve, carotid artery, jugular vein and mastoid. It was termed malignant, due to the high mortality rate and poor response to treatment. (2)