we used experimental animal data to derive a human acute reference dose of 1.33 g/ kg body weight, which corresponds to maximum concentration of TTX in shellï¬sh of 200 g/kg.
Where & Why Nickel is Used. Nickel-containing materials play a major role in our everyday lives â food preparation equipment, mobile phones, medical equipment, transport, buildings, power generation â the list is almost endless.
Nickel - Toxicity. 1  The major source of nickel exposure is oral consumption. 2  The average daily exposure does not pose a threat to human health. 3  Nickel compounds, as a group, are carcinogenic and cause lung and nasal cancer. 4  People can be exposed to nickel in the workplace by inhalation, ingestion, and contact with skin or eye.