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Antibiotics such as amoxicillin, cephalexin, or penicillin are used to treat strep throat. Antibiotics work only against bacterial infections such as strep throat. They will not help sore throats caused by allergies or viral infections such as colds. Antibiotics are commonly used to: 1  Kill the bacteria and shorten the time you are contagious.
Yes: Cephalexin will cover some of the bacteria that might cause sinus infection. It is freqently used for tonsillitis and skin infections. I don't generally use it for sinus infection.. Get help from a doctor now âº. Cephalexin: Not best choice for sinusitis, but it is is acute, the causative organism sensitive to first generation cephalosporins, and you absorb it adequately it may work well.