Coldest airmass of the fall season will spread eastward across the Middle Atlantic and Northeast this weekend. The cold front that brought sub-freezing temperatures to much of the Plains will advance eastward and sweep through the eastern third of the country this weekend. Numerous Freeze Warnings, Watches, and Frost Advisories are in effect.
What is Glipizide ER used for? Glipizide ER is used to treat type-2 diabetes. With type-2 diabetes, the body does not control the amount of blood sugar, which is caused by the abnormal use of insulin by the body. Glipizide ER lowers the blood sugar by causing the pancreas to produce insulin.
Endoplasmic reticulum (ER) is an elaborate cellular organelle essential for protein folding, calcium homeostasis, and lipid biosynthesis. Disruption of ER homeostasis imposes stress on the ER and subsequently leads to accumulation of unfolded or misfolded proteins in the ER lumenâa condition termed ER stress.n particular, the authors provided up-to-date information regarding the roles and mechanisms of the UPR signaling pathways in regulating phosphatidylcholine synthesis and ER biosynthesis. The paper by X. Zhang and K. Zhang discussed the links between ER stress, lipid droplet formation, and type II diabetes.