Depending upon the conditions, either nucleation or growth may be predominant over the other, and as a result, crystals with different sizes and shapes are obtained (Control of crystal size and shape constitutes one of the main challenges in industrial manufacturing, such as for pharmaceuticals).
For the region, see San Fernando Valley. San Fernando is a city located in the San Fernando Valley, in the northwestern region of Los Angeles County, California. It is completely surrounded by the City of Los Angeles.
San Mateo County was formed in 1856 after San Francisco County, one of the state's 18 original counties since California's statehood in 1850, was split apart. Until 1856, San Francisco's city limits extended west to Divisadero Street and Castro Street, and south to 20th Street.