22q11.2 deletion syndrome is caused by the deletion of a small section of chromosome 22. It results in a cleft palate, heart defects, autoimmune disorders, and more. The symptoms vary wildly and can be accompanied by learning disabilities and mental illness. Cystic fibrosis is caused by a point deletion.
The melody of Happy Birthday to You comes from the song  Good Morning to All , which has been attributed to American siblings Patty Hill and Mildred J. Hill in 1893, although the claim that the sisters composed the tune is disputed.
Federal Judge Rules 'Happy Birthday' Is In The Public Domain. A federal judge in Los Angeles has ruled that Happy Birthday should be in the public domain. Piano arrangements were copyrighted in 1935, but they apparently don't cover the lyrics. KELLY MCEVERS, HOST: And this story comes to us from the world of copyright.