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But the bottom line is that long-term, heavy cannabis use may impair the dopaminergic system, which could have a variety of negative effects on learning and behavior.. You might also like: Young Marijuana Users Show a Unique Response to Social Rejection, Study Finds.
Marijuana reduces stress by acting on the endocannabinoid system, the part of the brain that regulates pain, memory, and appetite. The brain busts out the Bob Marley when the THC interacts with a neurotransmitter called anandamide, producing a relaxed feeling.