22q11.2 deletion syndrome is caused by the deletion of a small section of chromosome 22. It results in a cleft palate, heart defects, autoimmune disorders, and more. The symptoms vary wildly and can be accompanied by learning disabilities and mental illness. Cystic fibrosis is caused by a point deletion.
The melody of Happy Birthday to You comes from the song  Good Morning to All , which has been attributed to American siblings Patty Hill and Mildred J. Hill in 1893, although the claim that the sisters composed the tune is disputed.
Garry Marshall (born Garry Kent Masciarelli; November 13, 1934 â July 19, 2016) was an American actor, director, producer, writer, and voice artist best known for creating Happy Days and its various spin-offs, developing Neil Simon's 1965 play The Odd Couple for television, and directing Pretty Woman, Runaway Bride, Valentine's Day, New Year's Eve, ...