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Lamina propria is loose connective tissue in a mucosa. Lamina propria supports the delicate mucosal epithelium, allows the epithelium to move freely with respect to deeper structures, and provides for immune defense. Compared to other loose connective tissue, lamina propria is relatively cellular.
1 Surrounding the mucosa is the submucosa layer of the stomach. 2  The submucosa is made up of various connective tissues, blood vessels, and nerves. 3  Connective tissues support the tissues of the mucosa and connect it to the muscularis layer. The esophagus connects to the stomach at a small region called the cardia. 2  The cardia is a narrow, tube-like region that opens up into the wider regions of the stomach. 3  Within the cardia is the lower esophageal sphincter, a band of muscle tissue that contracts to hold food and acid inside of the stomach.