we used experimental animal data to derive a human acute reference dose of 1.33 g/ kg body weight, which corresponds to maximum concentration of TTX in shellï¬sh of 200 g/kg.
Where & Why Nickel is Used. Nickel-containing materials play a major role in our everyday lives â food preparation equipment, mobile phones, medical equipment, transport, buildings, power generation â the list is almost endless.
Treatment of nickel allergy mainly involves the avoidance of nickel-containing materials. When a rash occurs as a result of exposure, the use of topical steroid creams is helpful to treat the symptoms. A test to determine the presence of nickel in jewelry and other metallic devices, called a dimethylglyoxime test, is available commercially.