what causes liver and spleen swelling 1 One of the most likely causes of an enlarged spleen is an infection, since swelling in the spleen signifies an increase in white blood cells that are trying to attack something threatening. 2  Leishmaniasis, a type of parasitic disease found in parts of the tropics, subtropics and southern Europe, can lead to an enlarged spleen. more information...
Yes, you can use acetaminophen and ibuprofen together. That combination of drugs controls very high fever in children. You need to know that they are not the similar drugs. Ibuprofen is one of the nonsteroidal anti-inflammatory drugs.
If you're uncomfortable, take acetaminophen (Tylenol, others), ibuprofen (Advil, Motrin IB, others) or aspirin. Read the label carefully for proper dosage, and be careful not to take more than one medication containing acetaminophen, such as some cough and cold medicines.