Phosphorylation of signal transduction molecules is a major activating event that leads to dramatic changes in tumor growth. Some TKs, such as epidermal growth factor receptor (EGFR)-TK, can autophosphorylate when activated, as well as phosphorylating other signaling molecules [2].
Risk indexes Definition: Categories of risk used to calculate fundamental beta, including (1) market variability, (2) earnings variability, (3) low valuation, (4) immaturity and smallness, (5) growth orientation, and (6) financial risk.
A composite index has a large number of factors that are averaged together to form a statistic representative of an overall market or sector. As an example, the NASDAQ Composite index is a market capitalization-weighted grouping of approximately 3,000 common stocks listed on the NASDAQ stock exchange. These indexes are useful tools for measuring and tracking price level changes for an entire stock market or sector, and an index provides a useful benchmark against which to measure an investor's portfolio performance.