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The mononuclear phagocyte system constitutes macrophage cells spread throughout the human body. The macrophages are long-lived cells that provide a major defense system against hostile elements through phagocytosis and subsequent intracellular destruction of the particle or cell.
Monocytes are white blood cells that are common to the blood of all vertebrates and they help the immune system to function properly. There are a number of reasons for a high monocyte count, which can also be called monocytosis. Some of the reasons can include stress, viral fevers, inflammation and organ necrosis.