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While these symptoms may indicate cancer, they may have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% is due to obesity, poor diet, lack of physical activity, and excessive drinking of alcohol. Other factors include certain infections, exposure to ionizing radiation and environmental pollutants.
General Information About Colorectal Cancer. 1  Key Points. 2  Colorectal cancer is a disease in which malignant (cancer) cells form in the tissues of the colon or the rectum. 3  Colorectal cancer is the second leading cause of death from cancer in the United States.