Also called: Broken bone. A fracture is a break, usually in a bone. If the broken bone punctures the skin, it is called an open or compound fracture. Fractures commonly happen because of car accidents, falls or sports injuries. Other causes are low bone density and osteoporosis, which cause weakening of the bones.
Milk Thistle Side Effects. Milk thistle is generally considered safe and well-tolerated, with very few cases of side effects ever reported. The most common side effects arenât serious and include gastrointestinal upset, such as a mild laxative effect.
Consumption of the oral form of milk thistle (standardized to 70% to 80% silymarin) at 420 mg/day in divided doses is considered safe for up to 41 months, based on clinical trial data. High-dose milk thistle has been used within the confines of clinical trials. Allergy to any plant in the Asteraceae family.