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Side Effects of L-arginine Hydrochloride For most people, taking L-arginine hydrochloride is thought to be relatively safe. Possible side effects of using L-arginine HCL capsules or powder include bloating, diarrhea, abdominal pain, gout, abnormalities in blood circulation, low blood pressure, inflammation of the lungs and airways, allergies and worsening of asthma symptoms. High-doses of L-arginine may be potentially fatal in children.
And in men with heart disease, arginase is upregulated or more active. This means that more Arginine is converted to the amino acid ornithine, which, as mentioned previously, can potentially lead to herpes outbreaks and other issues. L-Citrulline, on the other hand, seems to produce equal or better results at much lower dosages.