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The mononuclear phagocyte system constitutes macrophage cells spread throughout the human body. The macrophages are long-lived cells that provide a major defense system against hostile elements through phagocytosis and subsequent intracellular destruction of the particle or cell.
Monocytes are produced by the bone marrow and are a type of white blood cell. They account for up to 10 percent of the circulating white blood cells in the human body. Their main role is to destroy cancer cells and infectious organisms that invade the body.