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Long-term treatment with ibuprofen at a dose of 1200 mg/day does not increase the risk of renal impairment in elderly people (Griffin et al, 2000). Ibuprofen is associated with a low risk of renal toxicity in overdose (Jenkinson et al, 1988; Volans and Fitzpatrick, 1999).
Ibuprofen is the most commonly used OTC arthritis medication and is available in non-prescription strength, including tablets and fast release capsules, which may last four to six hours. Naproxen sodium is available non-prescription strength as an over-the-counter remedy for arthritis.aproxen. Naproxen sodium is available non-prescription strength as an over-the-counter remedy for arthritis. It carries similar side effects to ibuprofen; most commonly stomach upset, which may be reduced by taking it with food.