Actinic keratoses that develop on the lips are referred to as actinic cheilitis. The clinical appearance of an actinic keratosis is that of a small (several millimeters), red scaly papule or plaque, with induration and thickening of the epidermis.
1 Location: Ideally, the probe should be in close proximity to the forward or reverse primer, but should not overlap with a primer-binding site on the same strand. 2  Probes can be designed to bind to either strand of the target. 3  Melting temperature (Tm): Preferably, probes should have a Tm 6â8Â°C higher than the primers.
If so, a diode might be to thank for your circuit still being alive. A diode placed in series with the positive side of the power supply is called a reverse protection diode. It ensures that current can only flow in the positive direction, and the power supply only applies a positive voltage to your circuit. Forward bias: When the voltage across the diode is positive the diode is âonâ and current can run through. 2  The voltage should be greater than the forward voltage (V F) in order for the current to be anything significant.