Set the time delay of the closest driver as indicated in the screenshot below. In the plugins with eight output channels (4x10, 10x10, miniSharc), all delays appear on the Output tab. With these plugins, you can implement three-way or four-way speakers and use time delays to time-align all drivers.
Telomeres are the protective caps on the ends of chromosomes that affect how quickly cells age. They are combinations of DNA and protein that protect the ends of chromosomes and help them remain stable. As they become shorter, and as their structural integrity weakens, the cells age and die quicker.
Telomeres need to be protected from a cell's DNA repair systems because they have single-stranded overhangs, which look like damaged DNA. The overhang at the lagging strand end of the chromosome is due to incomplete end replication (see figure above). The overhang at the leading strand end of the chromosome is actually generated by enzymes that cut away part of the DNA 1 ^1 1 start superscript, 1, end superscript. In some species (including humans), the single-stranded overhangs bind to complementary repeats in the nearby double-stranded DNA, causing the telomere ends to form protective loops 3 ^3 3 start superscript, 3, end superscript.