Phosphorylation of signal transduction molecules is a major activating event that leads to dramatic changes in tumor growth. Some TKs, such as epidermal growth factor receptor (EGFR)-TK, can autophosphorylate when activated, as well as phosphorylating other signaling molecules [2].
Risk indexes Definition: Categories of risk used to calculate fundamental beta, including (1) market variability, (2) earnings variability, (3) low valuation, (4) immaturity and smallness, (5) growth orientation, and (6) financial risk.
FOCUS ON YOUR CRITICAL RISKS. The Coface Debtor Risk Assessment measures the probability that a company will default over a 12 month period, helping you determine whether a customer is an acceptable or a high risk. The DRA uses a scale from 0 to 10, with each of the 10 grades associated with a probability of default.