Disclaimers: This article explains what an FHA underwriter looks for during the loan review process. This is a general overview of events and does not include every possible underwriting scenario. Every mortgage situation is different because every borrower is different.
DIRECT GENETIC TESTING. Huntingtonâs disease has become a model for genetic testing in other adult-onset inherited disorders because the illness is relatively common, and there is widespread experience with it. Genetic testing programs began in 1986 with linkage testing and evolved to direct gene testing shortly after the gene was cloned in 1993.
Huntington disease (HD) is caused by expansion of the cytosine-adenine-guanine (CAG) trinucleotide repeats in the HTT gene (also known as the HD or IT15 gene) located on chromosome 4p16.3 that encodes the protein huntingtin [1-3].