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Repigmentation. Vitiligo is a common skin disorder in which the pigment producing cells of the skin (melanocytes) are absent or demonstrate lack of activity. As a result, lighter, depigmented patches of skin (target lesions) appear in different parts of the body due the lack of melanin (pigment).t is anticipated that treatment of vitiligo patients with SCENESSEÂ® could aid in the repigmentation of lesions by these same mechanisms-enhancing the increase and growth of melanocytes, assisting in their migration to depigmented areas of skin and activating pigment production within these regions.
Photoaging or photoageing (also known as dermatoheliosis) is a term used for the characteristic changes to skin induced by chronic UVA and UVB exposure. Tretinoin is the best studied retinoid in the treatment of photoaging.The deterioration of biological functions and ability to manage metabolic stress is one of the major consequences of the aging process. Aging is a complex, progressive process that leads to functional and esthetic changes in the skin.his process can result from both intrinsic (i.e., genetically determined) as well as extrinsic processes (i.e., environmental factors). Photoaging is attributed to continuous, long-term exposure to ultraviolet (UV) radiation of approximately 300â400 nm, either natural or synthetic, on an intrinsically aged skin.