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What is the Hardy-Weinberg principle and under what conditions does this principle apply? The Hardy-Weinberg principle states that in a large randomly breeding population, allelic frequencies will remain the same from generation to generation assuming that there i â¦ s no mutation, gene migration, selection or genetic drift.
If the alleles are different, they and the organism are heterozygous with respect to that gene. The word allele is a short form of allelomorph (other form), which was used in the early days of genetics to describe variant forms of a gene detected as different phenotypes.he frequency of alleles in a diploid population can be used to predict the frequencies of the corresponding genotypes (see Hardy-Weinberg principle). For a simple model, with two alleles: where p is the frequency of one allele and q is the frequency of the alternative allele, which necessarily sum to unity.