However, don't forget you can't go 60 through the towns and the border is going to take you a little bit of time, so I would budget about 18-20 hours for the drive total. I would take Mex. RT. 15 all the way down along the coast. If you want to do it in two days, I'd stop in Guaymas for an overnighter. Good luck.
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Question : Looking for the cheapest flight over the next 30 days? Answer : Since low prices are preferred, look at Mar 21st. As of Mar 20th, it's showing the cheapest ticket sales at $222. That is 30% below the average price for this route, so you can spend that extra money on a fun experience in Mexico City.