Actinic keratoses that develop on the lips are referred to as actinic cheilitis. The clinical appearance of an actinic keratosis is that of a small (several millimeters), red scaly papule or plaque, with induration and thickening of the epidermis.
1 Location: Ideally, the probe should be in close proximity to the forward or reverse primer, but should not overlap with a primer-binding site on the same strand. 2  Probes can be designed to bind to either strand of the target. 3  Melting temperature (Tm): Preferably, probes should have a Tm 6â8Â°C higher than the primers.
if you wout to do a PCR, you need to enhance both strands, so you need a primer for one strand, called the forward primer, which is the beginning of your gene, and an other primer that will begin the complementary strand (in the 5' end), it's called the reverse primer.You can call them also sense and antisense.f you wout to do a PCR, you need to enhance both strands, so you need a primer for one strand, called the forward primer, which is the beginning of your gene, and an other primer that will begin the complementary strand (in the 5' end), it's called the reverse primer. You can call them also sense and antisense.