anything done or to be done; anything requiring action or effort; business; concern: an affair of great importance. 2. affairs, matters of commercial or public interest or concern; the transactions of public or private business or finance:
Hyperlactatemia is defined as a persistent, mild to moderate (2-4 mmol/L) increase in blood lactate concentration without metabolic acidosis, whereas lactic acidosis is characterized by persistently increased blood lactate levels (usually >5 mmol/L) in association with metabolic acidosis.
But this lactate or lactic acid can build up in your bloodstream faster than you can burn it off. The point when lactic acid starts to build up is called the lactate threshold.. Some medical conditions can also bring on lactic acidosis, including: 1  Cancer.2  Seizures. 3  Liver failure. 4  Vitamin B deficiency.ut this lactate or lactic acid can build up in your bloodstream faster than you can burn it off. The point when lactic acid starts to build up is called the lactate threshold.. Some medical conditions can also bring on lactic acidosis, including: 1  Cancer. 2  Seizures. 3  Liver failure. 4  Vitamin B deficiency.