This information is used to determine the density of the air entering the combustion chamber (in conjunction with the IAT (Intake Air temperature) sensor), which is used when calculating the proper air/fuel mixture for the engine, especially at WOT since the system is not in closed-loop at this time.
The TTR gene provides instructions for producing a protein called transthyretin. This protein transports vitamin A (retinol) and a hormone called thyroxine throughout the body. To transport thyroxine, four transthyretin proteins must be attached (bound) to each other to form a four-protein unit (tetramer).
Alnylam Pharmaceuticals, Inc. , the leading RNAi therapeutics company, today announced the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy Designation (BTD) for patisiran, an investigational RNAi therapeutic targeting transthyretin (TTR) for the treatment of adults with hereditary transthyretin-mediated ATTR amyloidosis (hATTR amyloidosis) with polyneuropathy.