The pathogenesis of HIE in the newborn period involves the same key players that are also present in adults, namely energy crisis from hypoxia-ischemia, lactic acidosis, excitotoxicity, and free radicals, but there are some important modifiers, which account for different patterns of pathology in newborn babies.
Chordates (phylum Chordata) are a group of animals that includes all the vertebrates (subphylum Vertebrata), as well as two subphylum of invertebrates, the Urochordata (tunicates) and the Cephalochordata (lancelets).lso, the relationships of some chordate groups are not very well understood. 1  Phylum Chordata. 2  Subphylum Urochordata (Tunicates). 3  Subphylum Cephalochordata (Lancelets). 4  Class Myxini or Hyperotreti (hagfish). 5  Subphylum Vertebrata (Vertebrates-animals with backbones). 6  Class Conodonta (Conodonts).
The current consensus is that chordates are monophyletic, meaning that the Chordata include all and only the descendants of a single common ancestor, which is itself a chordate, and that craniates' nearest relatives are cephalochordates.t has also proved difficult to produce a detailed classification within the living chordates. Attempts to produce evolutionary  family trees  give results that differ from traditional classes because several of those classes are not monophyletic. As a result, vertebrate classification is in a state of flux.