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L-arginine has unpredictable effects on insulin and cholesterol-lowering agents. L-arginine may increase the effects of isosorbide mononitrate and other nitric oxide donors, such as glyceryl trinitrate and sodium nitroprusside. Side Effects. L-arginine has few reported adverse reactions. Nausea and diarrhea have been reported infrequently.
While your body does produce arginine on its own, the body can become deficient due to injuries or various health conditions. Signs that you may need to supplement your diet with L-arginine include slow healing of wounds, hair loss, constipation, and skin rashes.ou may have heard of arginine as a supplement thatâs popular among bodybuilders. It is often used by avid exercisers and athletes who are looking to lose body fat. While a magic pill for weight loss is not on the market yet, arginine might be just what you need to help convert more protein into muscle.