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Nephrotic syndrome is characterized by large proteinuria (>3.5 g per 1.73 m2 body surface area per day, or > 40 mg per square meter body surface area per hour in children), hypoalbuminemia (< 2,5 g/dl), hyperlipidaemia, and edema (which is generalized and also known as anasarca or dropsy) that begins in the face.
Nephrotic syndrome is characterised by the kidneys removing too much protein from the blood. 'Minimal change' disease (lipoid nephrosis) is the most common form of nephrotic syndrome in children. Treatment includes medications and dietary changes.