22q11.2 deletion syndrome is caused by the deletion of a small section of chromosome 22. It results in a cleft palate, heart defects, autoimmune disorders, and more. The symptoms vary wildly and can be accompanied by learning disabilities and mental illness. Cystic fibrosis is caused by a point deletion.
The melody of Happy Birthday to You comes from the song  Good Morning to All , which has been attributed to American siblings Patty Hill and Mildred J. Hill in 1893, although the claim that the sisters composed the tune is disputed.
This was the first version of the song. It was written by Lionel Richie and Michael Jackson. Performed by numerous singers and performing artists of the 80s and past. If one grew up in the 80s it brings back memories of love and importance of our role in society. The song itself evokes numerous emotions and thoughts. There have been other remakes of this song with performing artists in the past 10 years but the original hits a special spot.