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The osteon is the primary structure that makes up the hard outer layer of bones, which is generally known as â cortical bone .â Cortical bone, or compact bone, is dense, mature bone found in vertebrates such as mammals, amphibians, reptiles, and birds. It is this dense hard layer that gives a person or animal strength.
Osteoblasts are specialized, terminally differentiated products of mesenchymal stem cells. They synthesize very dense, crosslinked collagen, and several additional specialized proteins in much smaller quantities, including osteocalcin and osteopontin, which compose the organic matrix of bone.ndividual cells cannot make bone, and the group of organized osteoblasts together with the bone made by a unit of cells is usually called the osteon; the basis of this is discussed in Organization and ultrastructure of osteoblasts below.