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L-arginine has unpredictable effects on insulin and cholesterol-lowering agents. L-arginine may increase the effects of isosorbide mononitrate and other nitric oxide donors, such as glyceryl trinitrate and sodium nitroprusside. Side Effects. L-arginine has few reported adverse reactions. Nausea and diarrhea have been reported infrequently.
HelloCustomer. If you are going to take L-Arginine as a supplement the recommended dose is generally: 1 (one) 1,000 mg capsule twice a day. If you are going to take 3 capsules they should be taken 3 times a day, usually on an empty stomach unless you experience stomach upset.