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Most people who have piriformis syndrome get better with treatment and lifestyle changes. Failure to treat this condition can lead to permanent nerve damage, so be sure to follow your doctorâs instructions.
The piriformis runs over the sciatic nerve, and piriformis syndrome is thought to develop when the muscle becomes tight or spasms and places pressure on the sciatic nerve. This can cause pain in the lower back and/or pain that radiates to the buttocks and down the leg. Pain is often made worse by sitting.