Systemic lupus erythematosus, often abbreviated as SLE or lupus, is a systemic autoimmune disease (or autoimmune connective tissue disease) in which the bodyâs immune system mistakenly attacks healthy tissue.ystemic lupus erythematosus, often abbreviated as SLE or lupus, is a systemic autoimmune disease (or autoimmune connective tissue disease) in which the bodyâs immune system mistakenly attacks healthy tissue.
Natural selection will only cause evolution if there is enough genetic variation in a population. Before the discovery of Mendelian genetics, one common hypothesis was blending inheritance. But with blending inheritance, genetic variance would be rapidly lost, making evolution by natural selection implausible.
DNA and Mutations : The causes of mutations. 1. DNA fails to copy accurately. Most of the mutations that we think matter to evolution are naturally-occurring.. For example, when a cell divides, it makes a copy of its DNA  and sometimes the copy is not quite perfect. That small difference from the original DNA sequence is a mutation.