For a hotel built entirely out of salt bricks, itâs surprisingly luxurious. Salar de Uyuni, Uyuni; from $145. Tayka Hotel del Desierto. Nestled into a small hillside in the middle of nowhere, running largely on solar power, this hotel is like a five-star version of a disaster prepperâs shed.
Freckles are not a skin disorder, but people with freckles generally have a lower concentration of photo protective melanin, and are therefore more susceptible to the harmful effects of UV radiation. It is suggested that people whose skin tends to freckle should avoid overexposure to sun and use sunscreen.
Hermansky-Pudlak syndrome is another rare pigmentation disorder. It is an inherited autosomal recessive disease that results from the abnormal formation of intracellular vesicles and is linked to defects in 8 different genes. Its manifestations include a form of albinism that often presents as freckles or lentigines.