A new volcanic arc forms at the site of the easternmost transform, and many complications develop in SE Asia (Philippines, etc.) because of transforms turning into arcs, and various subduction-flips as thick (plateau-type) ocean crust refuses to subduct. A new subduction zone develops north of Australia.
Some of the causes of the European voyages of exploration were: 1  Alternate trade routes: Europe was dependent on Middle East countries for the import of spices and was looking for alternate trade routes to Asia and Africa to obtain spices (ginger, nutmeg, clove, cinnamon, etc.) and luxury goods (silk, gold, ivory, etc.) cheaply.
For instance, in a study of motor vehicle injuries, the agent (mechanical energy) and the host (driver) could be affected by the topography, the weather, and the actions of other drivers. In many infectious disease outbreaks, social and economic conditions cause overcrowding and lead to high levels of exposure.