In the social sciences, framing comprises a set of concepts and theoretical perspectives on how individuals, groups, and societies organize, perceive, and communicate about reality.
Neuroplasticity refers to the potential that the brain has to reorganize by creating new neural pathways to adapt, as it needs. Think of the neurological changes being made in the brain as the brain's way of tuning itself to meet your needs.
Exposure to a psychoactive substance can cause changes in the structure and functioning of neurons, as the nervous system tries to re-establish the homeostasis disrupted by the presence of the drug (see also, neuroplasticity).