Comments2 Share. This is a list of characters from the Nickelodeon animated comedy series SpongeBob SquarePants. The main characters in the show are SpongeBob SquarePants and his pet snail Gary, SpongeBob's friends Patrick, Squidward and Sandy, and two restaurateur rivals; Mr. Krabs and Plankton.
Technically, Imodium (Loperamide) is an opiate, but it only binds to the mu receptors in the GI tract; and doesn't cross the BBB (Blood Brain Barrier) into the CNS (Central Nervous System) like other opiates do.
Loperamide ... In vitro and animal studies show that IMODIUMÂ® (loperamide hydrochloride) acts by slowing intestinal motility and by affecting water and electrolyte movement through the bowel. Loperamide binds to the opiate receptor in the gut wall.