Berberine is best taken at doses between 900mg to 2200mg per day taken in 3-4 divided doses. High single doses of Berberine can cause some intestinal update, which is why the dose is split.
Mayan Civilization Rise & Decline (Theories) The Mayan civilization, centered in the tropical lowlands of what is now Guatemala, reached the peak of its power and influence around the sixth century BCE (BC). The Maya excelled at agriculture, pottery, hieroglyph writing, calendar-making and mathematics, and left behind an astonishing amount of impressive architecture and symbolic artwork.
The Whole Bushel. The Maya were the first Mesoamerican civilization, starting around 2600 B.C. They lasted the longest of all and are often viewed as the greatest Mesoamerican civilization. They built most of their great cities between A.D. 250 and A.D. 900.