Prednisone is intended for oral administration only. Adults: The initial dose is 5mg to 80mg daily depending on the condition being. treated, as a single dose after breakfast, as divided doses, or as a double dose on. alternate days. The maintenance dose is usually 5mg to 20mg daily. The dose should. be individualised according to the severity of the disease and the patients response. rather than by age or body weight. For adrenogenital syndrome: 5 to 10mg a day as a single dose. The usual adult prescribing limit is up to 250mg day.
View/Edit Mouse. Tissue plasminogen activator (abbreviated tPA or PLAT) is a protein involved in the breakdown of blood clots. It is a serine protease (EC 3.4.21.68) found on endothelial cells, the cells that line the blood vessels.
alteplase (tissue plasminogen activator, recombinant) Action. Availability. Adults weighing more than 67 kg (147 lb): Give total dosage of 100 mg as follows: 15 mg I.V. bolus over 1 to 2 minutes, then 50 mg I.V. over next 30 minutes, then 35 mg I.V. over next 60 minutes. Adults weighing 30 kg (66 lb) or more:Cathflo Activase-2 mg/2-ml concentration instilled in dysfunctional catheter.