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Estradiol levels also give important information on the functioning of the ovaries. This can help doctors evaluate menstrual problems, including abnormal bleeding or missing periods. The test may also be used in boys or girls to check for damage or disease of the testes, ovaries, or adrenal glands.
No. Circulating blood estradiol level after menopause is only ~10-20 pg/ml. This small quantity is actually not from the ovary, but rather a product of two conversion steps that happen in the body: androstenedione-->estrone-->estradiol. For a more detailed overview, http://emedicine.medscape.com/ar... might be useful.