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A study done on rats by the National institute on Alcohol Abuse and Alcoholism found that alcohol doesnât prevent azithromycin from killing your bacterial infection. But, drinking alcohol can cause temporary liver damage in some people. That may increase the severity of unpleasant side effects. Alcohol is also dehydrating. A hangover would worsen the nausea, vomiting, and headache that azithromycin may trigger.
Drinking any amount of alcohol with these medications can result in side effects such as flushing, headache, nausea and vomiting, and rapid heart rate. Keep in mind that some cold medicines and mouthwashes also contain alcohol. So check the label and avoid such products while taking these antibiotics. Although alcohol doesn't reduce the effectiveness of most antibiotics, it can reduce your energy and delay how quickly you recover from illness. So, it's a good idea to avoid alcohol until you finish your antibiotics and are feeling better.