Demodectic Mange in Dogs. Save to mypetMD. Mange (demodicosis) is an inflammatory disease in dogs caused by various types of the Demodex mite. When the number of mites inhabiting the hair follicles and skin of the dog become exorbitant, it can lead to skin lesions, genetic disorders, problems with the immune system and hair loss (alopecia).
Osteoblast, large cell responsible for the synthesis and mineralization of bone during both initial bone formation and later bone remodeling. Osteoblasts form a closely packed sheet on the surface of the bone, from which cellular processes extend through the developing bone. They arise from the differentiation of osteogenic cells in the periosteum, the tissue that covers the outer surface of the bone, and in the endosteum of the marrow cavity. This cell differentiation requires a regular supply of blood, without which cartilage-forming chondroblasts, rather than osteoblasts, are formed.
Cartilage cells form cells called OSTEOBLASTS. These cells produce bone matrix and once the cell is enclosed in bone matrix it is considered to be a mature bone cell and called an OSTEOCYTE; Growth in thickness of bone occurs as osteoblasts from beneath the periosteum produce bone matrix and build compact bone just underneath the periosteum