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The Free Dictionary describes a complexation reaction as a chemical reaction between a ligand and a metal ion. A ligand is an ionic entity with at least one atom that contains an unshared pair of electrons. Keep Learning.
Type 4 hypersensitivity is often called delayed type hypersensitivity as the reaction takes two to three days to develop. Unlike the other types, it is not antibody mediated but rather is a type of cell-mediated response.CD4+ helper T cells recognize antigen in a complex with Class II major histocompatibility complex.ctivated CD8+ T cells destroy target cells on contact, whereas activated macrophages produce hydrolytic enzymes and, on presentation with certain intracellular pathogens, transform into multinucleated giant cells.