Human anthrax vaccines were developed by the Soviet Union in the late 1930s and in the US and UK in the 1950s.The current vaccine approved by the U.S. Food and Drug Administration (FDA) was formulated in the 1960s.Currently administered human anthrax vaccines include acellular (USA, UK) and live spore (Russia) varieties.All currently used anthrax vaccines show considerable local and general reactogenicity (erythema, induration, soreness, fever) and serious adverse reactions occur in about 1% of recipients.New third-generation vaccines being researched include recombinant live vaccines and recombinant sub-unit vaccines.he current vaccine approved by the U.S. Food and Drug Administration (FDA) was formulated in the 1960s. Currently administered human anthrax vaccines include acellular (USA, UK) and live spore (Russia) varieties.
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