Part 1 Climate Change and Corresponding Efforts in China. Many observations in recent 100 years show that the earthâs climate is now. experiencing significant change characterized by global warming. And the trend of. climate change in China is generally consistent with that of global climate change.
Primase synthesizes the RNA primer that is used to start an Okazaki fragment on the lagging strand. DNA polymerase III continues to add nucleotides to the leading strand right at the replication fork. DNA polymerase I (not at the replication fork) replaces the RNA primers with DNA nucleotides. DNA ligase, also not at the replication fork fuses the new nucleotides produced by polymerase I with the adjacent strand. Replication continues until there are two completely seperate DNA strands that are identical.
When DNA is being replicated, it forms a replication fork that was created during the helicase process that separates the DNA strand. The strands that are separated are called the leading strand and the lagging strand accordingly. The leading strand is synthesized in the 5'-3' direction.n initiation, many replication proteins called initiators convert the DNA into a replication fork. This is accomplished first by the initiator proteins assembling around the DNA which causes melting of the dsDNA (double stranded DNA) origin.