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Alcohol dilates peripheral blood vessels, but has been known to actually. constrict some blood vessels in the brain, lowering the oxygen content. Alcohol dilates peripheral blood vessels, but has been known to actually  constrict some blood vessels in the brain, lowering the oxygen content.
1 Both alcohol and Cialis are vasodilators. Vasodilators are substances that lower blood pressure by relaxing the walls of blood vessels and opening them wider.  Alcohol alone acts as a vasodilator, so when it is coupled with Cialis, your blood pressure falls. This can create erratic blood pressure patterns.