Berberine is best taken at doses between 900mg to 2200mg per day taken in 3-4 divided doses. High single doses of Berberine can cause some intestinal update, which is why the dose is split.
Mayan Civilization Rise & Decline (Theories) The Mayan civilization, centered in the tropical lowlands of what is now Guatemala, reached the peak of its power and influence around the sixth century BCE (BC). The Maya excelled at agriculture, pottery, hieroglyph writing, calendar-making and mathematics, and left behind an astonishing amount of impressive architecture and symbolic artwork.
It took them a long time (170 years) to finish doing this because the Mayans had no capital city and each city had a different culture. The last Mayan states, the Itza city of Tayasal and the Ko'woj city of Zacpeten, still had people living in them late into the 17th century.