9 thoughts on âProtein Pile-up: Common Cause of Brain Diseaseâ. 1  Interesting article by Dr. Collins. 2  This is an exciting discovery and Iâll be looking forward and following new developments. 3  You make this sound like it is normally happening to everyone.
Summer months are pretty hot, especially at the bottom of the canyon, where it can be well over a hundred. The best hiking weather is generally April and May, and late September through October. But then, these are the hardest times to get backcountry permits. You would send your applicAtion on May 1 for a permit date any time in September.
1 The Grand Canyon Shuttle is no longer in business.  The (928-638-2820) runs between the north and south rims of the park once each day, in each direction, between May 15th and October 15, with a limited schedule between October 16 and October 31.The travel time is about 4 1/2 hours each way. Reservations required.