Strep throat itself is not particularly dangerous but the infection can worsen, especially if it goes untreated. If strep throat does not improve within two days of beginning treatment, it could indicate the presence of another infection, the spread of strep to other areas outside the throat, or an inflammatory reaction.
Schematic of key mitochondrial metabolic pathways 1 expert reviews in molecular medicine Figure 1. Schematic of key mitochondrial metabolic pathways. (a) Carbohydrate metabolism. Pyruvate produced from glycolysis undergoes oxidative decarboxylation to acetyl CoA, which is then oxidised in an eight-step process known as the tricarboxylic acid (TCA) cycle.
Remember that permeabilizing the inner mitochondrial membrane to proton dissipates the electrochemical gradient in which energy from electron transport is stored. Uncoupling the ETS system from oxidative phosphorylation is potentially lethal. In an uncoupled system oxidative phosphorylation does not occur. An intact membrane is required for oxidative phosphorylation. 2  The inner mitochondrial membrane is impermeable to the diffusion of ions, such as H+, OH-, K+, and Cl-that would destroy the electrochemical gradient. 3  3. ETS proteins span the inner mitochondrial membrane.