Strep throat itself is not particularly dangerous but the infection can worsen, especially if it goes untreated. If strep throat does not improve within two days of beginning treatment, it could indicate the presence of another infection, the spread of strep to other areas outside the throat, or an inflammatory reaction.
Schematic of key mitochondrial metabolic pathways 1 expert reviews in molecular medicine Figure 1. Schematic of key mitochondrial metabolic pathways. (a) Carbohydrate metabolism. Pyruvate produced from glycolysis undergoes oxidative decarboxylation to acetyl CoA, which is then oxidised in an eight-step process known as the tricarboxylic acid (TCA) cycle.
Mitochondria extrude protons across their inner membrane to generate the mitochondrial membrane potential (ÎÎ¨m) and pH gradient (ÎpHm) that both power ATP synthesis. Mitochondrial uptake and efflux of many ions and metabolites are driven exclusively by ÎpHm, whose in situ regulation is poorly characterized.