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Imipramine (Tofranil) is the medication for panic disorder that has been most thoroughly studied, with at least 10 double-blind, placebo-controlled studies supporting its efficacy in the acute treatment of panic disorder.6 Clomipramine (Anafranil) has shown similar results in several double-blind trials as well.
Anxiety medications are used either alone or in combination with psychotherapy to treat a number of different disorders all classified as âanxiety disorders.â These include: 1  Generalized anxiety disorder (GAD) 2  Phobias. 3  Obsessive-compulsive disorder (OCD) 4  Post-traumatic stress disorder (PTSD)  Panic disorder (PD)