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Introduction: Coagulation defects. Description of Coagulation defects. Coagulation defects (medical condition): A general term for a number of conditions that stops the blood from clotting and hence results in ...more. Coagulation defects: See also: Bleeding disorders: Â»Introduction: Bleeding disorders. Â»Symptoms of Bleeding disorders.
Alternatively known as antiphospholipid antibody syndrome, lupus anticoagulant syndrome is a coagulation disorder which causes formation of thrombosis in blood vessels. In lupus anticoagulant syndrome, there is affectation of the mitral valve, masses may form on this area or may thicken, leading to blood regurgitation. 2  Low platelet count. 3  Patient may show episodes of bleeding, especially from the nose and gums. 4  Petechiae may also appear, suggesting bleeding into the skin.