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A RealAge answered. A dentist may prescribe antibiotics before a root canal procedure to improve the chances of a successful outcome. Antibiotics are usually continued after the procedure as well. The dentist may also recommend the use of a nonsteroidal anti-inflammatory medicine like ibuprofen or naproxen (available over the counter), or oxaprozin or ketoralac (prescription only) after the procedure. This can reduce inflammation and improve healing.
A , Dentist, answered. You can expect some discomfort after a root canal for at least 3-5 days. In most cases, over-the-counter pain medication like Ibuprofen 400-800 mg (2-4 Advil or Motrin) will do the trick. I often prescribe prescription pain medication just in case the pain is greater than normal.