Strep throat itself is not particularly dangerous but the infection can worsen, especially if it goes untreated. If strep throat does not improve within two days of beginning treatment, it could indicate the presence of another infection, the spread of strep to other areas outside the throat, or an inflammatory reaction.
Schematic of key mitochondrial metabolic pathways 1 expert reviews in molecular medicine Figure 1. Schematic of key mitochondrial metabolic pathways. (a) Carbohydrate metabolism. Pyruvate produced from glycolysis undergoes oxidative decarboxylation to acetyl CoA, which is then oxidised in an eight-step process known as the tricarboxylic acid (TCA) cycle.
Mitochondrial dysfunction produces syndromes involving muscle and the central nervous system. Although some energy can be obtained quickly from glucose or glycogen through anaerobic glycolysis, most of the energy derives from oxidation of carbohydrates and fatty acids in the mitochondria. The common metabolic product of sugars and fats is acetyl-CoA, which enters the Krebs cycle.