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Epimedium is commonly known as horny goat weed, it is a genus of flowering plants in the family Berberidaceae. This plant contains icariin, which is a PDE5 inhibitor similar to the active ingredient of Viagra sildenafil.It is thus considered as a potential aphrodisiac and used in the treatment for erectile dysfunction.It is also known by other names such as Bishopâs Hat, Rowdy Lamb Herb, Fairy Wings and Barrenwort.ide Effects. There are many types of Epimedium that may not be safe if used for a longer period, high doses can cause various side effects such as dry mouth, dizziness, nosebleed, thirst and vomiting. Taking it in large amounts might lead to serious complications such as breathing problems and spasms.
Sildenafil should not be taken by people who take nitrates such as nitroglycerin, as this may result in a severe and potentially fatal drop in blood pressure. It acts by inhibiting cGMP-specific phosphodiesterase type 5 (PDE5), an enzyme that promotes degradation of cGMP, which regulates blood flow in the penis.