Prednisone is intended for oral administration only. Adults: The initial dose is 5mg to 80mg daily depending on the condition being. treated, as a single dose after breakfast, as divided doses, or as a double dose on. alternate days. The maintenance dose is usually 5mg to 20mg daily. The dose should. be individualised according to the severity of the disease and the patients response. rather than by age or body weight. For adrenogenital syndrome: 5 to 10mg a day as a single dose. The usual adult prescribing limit is up to 250mg day.
View/Edit Mouse. Tissue plasminogen activator (abbreviated tPA or PLAT) is a protein involved in the breakdown of blood clots. It is a serine protease (EC 3.4.21.68) found on endothelial cells, the cells that line the blood vessels.
There are three major classes of fibrinolytic drugs: tissue plasminogen activator (tPA) , streptokinase (SK) , and urokinase (UK) . While drugs in these three classes all have the ability to effectively dissolve blood clots, they differ in their detailed mechanisms in ways that alter their selectivity for fibrin clots.treptokinase and anistreplase are used in acute myocardial infarction, arterial and venous thrombosis, and pulmonary embolism. These compounds are antigenic because they are derived from streptococci bacteria. 1  Natural streptokinase (SK) is isolated and purified from streptococci bacteria.