Do not take Simvastatin Tablets. 1  If you are allergic (hypersensitive) to simvastatin. 2  If you are allergic to any of the other ingredients of Simvastatin Tablets (these are listed in section 6 Further Information). 3  If you are pregnant or planning to become pregnant.  If you are breast- 1 feeding. If you have liver problems.
Just a tiny amount of an impurity in a drug could cause a great deal of harm to a patient. Samples of chemicals that are synthesised must be checked for purity. This is often done by carrying out a titration. A titration is used to measure the volume of one solution that exactly reacts with another solution. Steps of titration. A titration is carried out using a number of steps: If the sample is a solid, it is weighed using an accurate balance, and then dissolved to make up a known volume of solution (usually 100cm3). A pipette is used to measure accurately a volume of this solution - for example, 10cm3.
Dean and Webb titration a test for measuring antibody in which varying dilutions of antibody are mixed with a constant quantity of antiserum; antibody activity is determined by the dilution in which flocculation occurs most rapidly, i.e., the end point.