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Prophylaxis of gout flares: If the original colchicine dose was 0.6 mg twice daily, 0.6 mg daily or 0.3 mg twice daily should be given. For an original dose of 0.6 mg daily, the adjusted dose is 0.3 mg daily.Treatment of gout flares: Take 1.2 mg Ã 1 dose of colchicine; at least 3 days should elapse before repeating.rophylaxis of gout flares: If the original colchicine dose were 0.6 mg twice daily, 0.3 mg should be given once daily. For an original dose of 0.6 mg daily, the adjusted dose is 0.3 mg every other day.
The daily dose may be administered once a day (or in equallydivided doses every 12 hours). The usual duration of therapy is 7 to 14days. Adults: The usual adult daily dose is 1 to 2 grams given once a day (or in equallydivided doses twice a day) depending on the type and severity of infec-tion.