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Introduction: Coagulation defects. Description of Coagulation defects. Coagulation defects (medical condition): A general term for a number of conditions that stops the blood from clotting and hence results in ...more. Coagulation defects: See also: Bleeding disorders: Â»Introduction: Bleeding disorders. Â»Symptoms of Bleeding disorders.
Disseminated intravascular coagulation (DIC) is characterized by systemic activation of blood coagulation, which results in generation and deposition of fibrin, leading to microvascular thrombi in various organs and contributing to multiple organ dysfunction syndrome (MODS).Consumption and subsequent exhaustion of coagulation proteins and platelets ...