Berberine is best taken at doses between 900mg to 2200mg per day taken in 3-4 divided doses. High single doses of Berberine can cause some intestinal update, which is why the dose is split.
Mayan Civilization Rise & Decline (Theories) The Mayan civilization, centered in the tropical lowlands of what is now Guatemala, reached the peak of its power and influence around the sixth century BCE (BC). The Maya excelled at agriculture, pottery, hieroglyph writing, calendar-making and mathematics, and left behind an astonishing amount of impressive architecture and symbolic artwork.
The Maya, Inca, and Aztecs built great civilizations in Mexico and in Central and South America between 1,800 and 500 years ago. The first of these was the Maya civilization. About 2,800 years ago, people known as the Maya lived in farming villages on the Yucatan Peninsula and the highlands to the south. From about A.D. 250 to A.D. 900, they built city-states in Central America that included great pyramid temples and public plazas featuring huge stone columns that recounted their history.