Demodectic Mange in Dogs. Save to mypetMD. Mange (demodicosis) is an inflammatory disease in dogs caused by various types of the Demodex mite. When the number of mites inhabiting the hair follicles and skin of the dog become exorbitant, it can lead to skin lesions, genetic disorders, problems with the immune system and hair loss (alopecia).
Osteoclasts are found on top of or next to existing bone tissue, sometimes in close proximity to osteoblasts. There is on-going race between the two cell types; osteoblasts make bone tissue while osteoclasts reabsorb it.
There are three types of cell present in bone that are of particular interest â osteoblasts, osteocytes and osteoclasts, which are respectively responsible for the production, maintenance and resorption of bone. 1  Osteoblasts. 2  Mononucleated âbone-formingâ cells found near the surface of bones. Mononucleated âbone-formingâ cells found near the surface of bones. 2  They are responsible for making osteoid, which consists mainly of collagen. 3  The osteoblasts then secrete alkaline phosphatase to create sites for calcium and phosphate deposition, which allows crystals of bone mineral to grow at these sites.