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Alcohol dilates peripheral blood vessels, but has been known to actually. constrict some blood vessels in the brain, lowering the oxygen content. Alcohol dilates peripheral blood vessels, but has been known to actually  constrict some blood vessels in the brain, lowering the oxygen content.
A study by researchers at the University of Maryland found that laughing while watching a comedic film causes your blood vessels to dilate by 22 percent. That's because when you laugh, the tissues forming the lining of your blood vessels expand and make room for an increase in blood flow.