Prednisone is intended for oral administration only. Adults: The initial dose is 5mg to 80mg daily depending on the condition being. treated, as a single dose after breakfast, as divided doses, or as a double dose on. alternate days. The maintenance dose is usually 5mg to 20mg daily. The dose should. be individualised according to the severity of the disease and the patients response. rather than by age or body weight. For adrenogenital syndrome: 5 to 10mg a day as a single dose. The usual adult prescribing limit is up to 250mg day.
View/Edit Mouse. Tissue plasminogen activator (abbreviated tPA or PLAT) is a protein involved in the breakdown of blood clots. It is a serine protease (EC 3.4.21.68) found on endothelial cells, the cells that line the blood vessels.
â¢ 1 unit (bag) per 10 kg of body weight every 7 to 14 days. (Level IV evidence, grade C recommendation.). Management of bleeding related to thrombolytic therapy. Cryoprecipitate can be used to manage intracranial bleeding in patients during or after administration of tissue plasminogen activator (tPA).hysicians contemplating the use of cryoprecipitate (see Table), should keep in mind the following general considerations: â¢ In British Columbia, informed consent is required for the transfusion of cryoprecipitate.