Heavy drinking can cause the number of oxygen-carrying red blood cells to be abnormally low. This condition, known as anemia, can trigger a host of symptoms, including fatigue, shortness of breath, and lightheadedness.
The human leukocyte antigen system or complex is a gene complex encoding the major histocompatibility complex proteins in humans. These cell-surface proteins are responsible for the regulation of the immune system in humans. The HLA gene complex resides on a 3 Mbp stretch within chromosome 6p21. HLA genes are highly polymorphic, which means that they have many different alleles, allowing them to fine-tune the adaptive immune system. The proteins encoded by certain genes are also known as antigen
Additional genes with class 2 MHC locus. MHC 2 locus also encodes: -HLA-DM: facilitates removal of invariant chain derived CLIP protein and binding of endosomal peptide to Class 2 molec. -Proteasome: Cytosolic protease complex cleaves proteins into small peptides. Presented to class 1 molec.ositive selection of T cells in thymus 2. Presentation of antigenic peptides to T cells 3. Encodes some complement proteins, cytokines, proteins in antigen processing 4.