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Introduction: Coagulation defects. Description of Coagulation defects. Coagulation defects (medical condition): A general term for a number of conditions that stops the blood from clotting and hence results in ...more. Coagulation defects: See also: Bleeding disorders: Â»Introduction: Bleeding disorders. Â»Symptoms of Bleeding disorders.
Some diseases and conditions can disrupt the body's normal blood clotting process and lead to disseminated intravascular coagulation (DIC). These diseases and conditions include: 1  Sepsis (an infection in the bloodstream). 2  Surgery and trauma. 3  Cancer. 4  Serious complications of pregnancy and childbirth.