Groups are determined by PRECIPITIN test, serologic test to measure a specific reaction between antigen (C carbohydrate, located in the cell wall) and antibody which results in a visible precipitate. Group A Streptococci (Streptococcus pyogenes) is among the most important human pathogens.
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Some types of autoimmune diseases that affect the liver can also cause cirrhosis. For example, there is also a disease called primary biliary cirrhosis (PBC). In PBC, the bile ducts in the liver are damaged and even destroyed which can lead to cirrhosis. People with advanced PBC have a high risk of liver cancer.