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In clinical studies, Cialis began to work in as little as 30 minutes. For most people, though, it begins working within one hour. There are a number of factors that can increase or decrease how long Cialis lasts.
The recommendation is to take Cialis 30 minutes prior to sexual activity, while with Viagra and Levitra, users are instructed to take the drug 60 minutes before sexual activity. Generally, the effects of Cialis last 24 to 36 hours after taking it.osted by: Mary Hiers in Cialis April 8, 2014 Comments Off on Cialis: How to Take it and How Long it Lasts 28329 Views. Cialis is a drug used to treat erectile dysfunction (ED). Cialis is among the top 100 selling drugs in the world.