Nextdoor is the private social network for your neighborhood. On Nextdoor, neighbors create private groups for their neighborhoods where they can ask questions, get to know one another, and exchange local advice and recommendations.
Up-regulation is a process that occurs within a cell triggered by a signal (originating internal or external to the cell), which results in increased expression of one or more genes and as a result the protein(s) encoded by those genes.
As in prokaryotes, eukaryotic repressor molecules can sometimes bind to silencer elements in the vicinity of a gene and inhibit the binding, assembly, or activity of the transcription complex, thus turning off expression of a gene. Positive regulation by TFs that are activators is common in eukaryotes.truhl, K. Fundamentally different logic of gene regulation in eukaryotes and prokaryotes. Cell 98, 1â4 (1999). Sproul, D., Gilbert, N., & Bickmore, W. The role of chromatin structure in regulating the expression of clustered genes.