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But denosumab is a first-in-class drug: It's a biologic, which means it will likely be much more expensive than its competitor drugs, some of which are available as cheaper generics. The drug also boasts an extremely convenient dosing regimen -- subcutaneous injection every six months.
High doses of prednisone are common, as well as immunosuppressants and anti-cancer agents to treat the severe pain and swelling. A newer class of RA drugs is the biologic drugs called TNF-alpha inhibitors, sold under the brand names Humira, Enbrel, and Remicade. While these drugs are aggressively promoted, there are still concerns about their safety.