n. pl. locÂ·ules or locÂ·uÂ·li (-lÄ«â²). A small cavity or compartment within an organ or part of an animal or plant, as any of the cavities within a plant ovary. [Latin.
Competitive inhibition is a form of enzyme inhibition where binding of the inhibitor to the active site on the enzyme prevents binding of the substrate and vice versa. Most competitive inhibitors function by binding reversibly to the active site of the enzyme.
A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION. Definition (NCI). A synthetic piperazine derivative and an alpha-1 adrenergic receptor inhibitor used primarily as an anti-hypertensive.