1 One form of Stickler syndrome is due to mutation in the COL2A1 gene on chromosome 12 in region 12q13.11-q13.2. It is termed Stickler syndrome, type I and symbolized STL1.  A second form of Stickler syndrome is caused by mutation in the COL11A1 gene on chromosome 1 in region 1p21.
Recent technical advances in this field will give rise to conceptual advances and there is every reason to believe that a new field of cancer genetics is emerging, named here Oncogenetics: a branch of genetics describing the cause of effects of genes causing neoplasia.
/carÂ·cinÂ·oÂ·gen/ (kahr-sinÂ´ah-jen) any substance which causes cancer.carcinogenÂ´ic. epigenetic carcinogen one that does not itself damage DNA but causes alterations that predispose to cancer. genotoxic carcinogen one that reacts directly with DNA or with macromolecules that then react with DNA.