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Some people are born with a poor sense of smell or taste. Upper respiratory infections are blamed for some losses, and injury to the head can also cause smell or taste problems. Loss of smell and taste may result from polyps in the nasal or sinus cavities, hormonal disturbances, or dental problems.
Although loss of smell is rarely a symptom of a serious condition, even a partial loss of smell could cause you to lose interest in eating, which could possibly lead to weight loss, malnutrition or even depression. The common cold with nasal congestion is the most common cause for a partial, temporary loss of smell.