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Prophylaxis of gout flares: If the original colchicine dose was 0.6 mg twice daily, 0.6 mg daily or 0.3 mg twice daily should be given. For an original dose of 0.6 mg daily, the adjusted dose is 0.3 mg daily.Treatment of gout flares: Take 1.2 mg Ã 1 dose of colchicine; at least 3 days should elapse before repeating.rophylaxis of gout flares: If the original colchicine dose were 0.6 mg twice daily, 0.3 mg should be given once daily. For an original dose of 0.6 mg daily, the adjusted dose is 0.3 mg every other day.
Use lowest effective dose for shortest duration. Arthritis, spondylitis: 275mg or 550mg twice daily. Tendinitis, bursitis: Initially 550mg, then 550mg every 12 hrs or 275mg every 6â8 hrs; max 1.375g (first day), then max 1.1g/day. Acute gout: 825mg once then 275mg every 8 hrs. Renal or hepatic impairment, elderly: consider lower doses.