1. something that is to happen or has happened to a particular person or thing; lot or fortune. 2. the predetermined, usu. inevitable, course of events. 3. the power or agency that determines the course of events.
Alternating between ibuprofen and acetaminophen every 2 hours because you have to wait 4 hours for each of them to take a second dose of the same thing. So instead you take a dose of Acetaminophen now, then Ibuprofen in 2 hours and back to Acetaminophen 2 hours later as needed.
Ibuprofen can make aspirin less effective in protecting your heart and blood vessels. If you must use both medications, take the Advil at least 8 hours before or 30 minutes after you take the aspirin (non-enteric coated form). Ask a doctor or pharmacist before using any cold, allergy, or pain medicine. Many medicines available over the counter contain aspirin or other medicines similar to ibuprofen.