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But denosumab is a first-in-class drug: It's a biologic, which means it will likely be much more expensive than its competitor drugs, some of which are available as cheaper generics. The drug also boasts an extremely convenient dosing regimen -- subcutaneous injection every six months.
Prolia: Another wonder drug that wasn't. Prolia: Another wonder drug that wasn't. Monkeys developed tooth and jaw abscesses and two died of protozoal infections. Human subjects developed cervical, ovarian, pancreatic, gastric and thyroid cancers and breast cancer was the most common adverse event that led to discontinuation in trials.