1 A physical change, such as a state change or dissolving, does not create a new substance, but a chemical change does. 2  In a chemical reaction, the atoms and molecules that interact with each other are called reactants. 3  In a chemical reaction, the atoms and molecules produced by the reaction are called products. In a chemical reaction, the atoms and molecules produced by the reaction are called products. 2  In a chemical reaction, only the atoms present in the reactants can end up in the products. 3  No new atoms are created, and no atoms are destroyed.
Humira (adalimumab) is a biologic drug that works by blocking a protein known as TNF-alpha. Normally, TNF-alpha helps fight infection, but in excess amounts, it can cause painful inflammation and severe joint damage -- common symptoms of rheumatoid arthritis and other forms of inflammatory arthritis.
Other studies of Remicade and methotrexate indicate that the two medications together can successfully reduce symptoms of psoriasis and psoriatic arthritis, the researchers report. Studies of Humira and Enbrel in conjunction with methotrexate also revealed the combination to be more effective than the biologic alone.