Do not take Simvastatin Tablets. 1  If you are allergic (hypersensitive) to simvastatin. 2  If you are allergic to any of the other ingredients of Simvastatin Tablets (these are listed in section 6 Further Information). 3  If you are pregnant or planning to become pregnant.  If you are breast- 1 feeding. If you have liver problems.
Just a tiny amount of an impurity in a drug could cause a great deal of harm to a patient. Samples of chemicals that are synthesised must be checked for purity. This is often done by carrying out a titration. A titration is used to measure the volume of one solution that exactly reacts with another solution. Steps of titration. A titration is carried out using a number of steps: If the sample is a solid, it is weighed using an accurate balance, and then dissolved to make up a known volume of solution (usually 100cm3). A pipette is used to measure accurately a volume of this solution - for example, 10cm3.
Best Answer: In an acid-base titration the idea is to carry out a neutralization reaction between an acid solution and a base solution in order to determine the concentration of either an unknown acid or base solution.This requires that you know the concentration of the other solution as accurately as possible.eport Abuse. Standardization is where you accurately determine the concentration of the titrant (the liquid in the buret) before performing a titration. Alkaline solutions like NaOH are standardized using potassium hydrogen phthalate, a very stable organic acid.