Prednisone is intended for oral administration only. Adults: The initial dose is 5mg to 80mg daily depending on the condition being. treated, as a single dose after breakfast, as divided doses, or as a double dose on. alternate days. The maintenance dose is usually 5mg to 20mg daily. The dose should. be individualised according to the severity of the disease and the patients response. rather than by age or body weight. For adrenogenital syndrome: 5 to 10mg a day as a single dose. The usual adult prescribing limit is up to 250mg day.
View/Edit Mouse. Tissue plasminogen activator (abbreviated tPA or PLAT) is a protein involved in the breakdown of blood clots. It is a serine protease (EC 3.4.21.68) found on endothelial cells, the cells that line the blood vessels.
Also, much has been done to fight the effects of stroke. There is a clot-dissolving drug called tissue plasminogen activator (tPA) to treat stroke. tPA can stop a stroke in progress and reduce disability from stroke by breaking up a blood clot that might be stopping the flow of blood to the brain. But to be eligible for tPA, you must seek emergency treatment right away and have a clot-caused stroke. It must be given within 3 to 4.5 hours after symptoms start.