Demodectic Mange in Dogs. Save to mypetMD. Mange (demodicosis) is an inflammatory disease in dogs caused by various types of the Demodex mite. When the number of mites inhabiting the hair follicles and skin of the dog become exorbitant, it can lead to skin lesions, genetic disorders, problems with the immune system and hair loss (alopecia).
Osteoblast, large cell responsible for the synthesis and mineralization of bone during both initial bone formation and later bone remodeling. Osteoblasts form a closely packed sheet on the surface of the bone, from which cellular processes extend through the developing bone. They arise from the differentiation of osteogenic cells in the periosteum, the tissue that covers the outer surface of the bone, and in the endosteum of the marrow cavity. This cell differentiation requires a regular supply of blood, without which cartilage-forming chondroblasts, rather than osteoblasts, are formed.
Two types of cells that are of great importance in the process are osteoblasts and osteoclasts. Osteoblasts, used mainly in intramembranous ossification, are the specialized cells in bone tissue that deposit calcium into the protein matrix of bone (collagen).ometimes compact bone is formed on the surfaces of existing bone tissue and they must be eroded away by specialized cells called osteoblasts. The crystals of apatite extracted from the bone tissue are delivered to blood and tissues on demand. Growth in the length of bones continues until about the age of 25.