Nextdoor is the private social network for your neighborhood. On Nextdoor, neighbors create private groups for their neighborhoods where they can ask questions, get to know one another, and exchange local advice and recommendations.
Up-regulation is a process that occurs within a cell triggered by a signal (originating internal or external to the cell), which results in increased expression of one or more genes and as a result the protein(s) encoded by those genes.
Most homeostatic regulatory mechanisms involve negative feedback. Consider the control of body temperature, a process called thermoregulation. In thermoregulation, the relationship between heat loss, which occurs primarily at the body surface, and heat production, which occurs in all active tissues, is altered. The control center for thermoregulation is in the hypothalamus, a region of the brain (Figure 1-4a).