Sickle cell disease occurs from genetic changes that cause abnormalities in hemoglobin molecules: 1  Hemoglobin A (HbA) . 2  HbA is the hemoglobin molecule found in normal red blood cells during childhood and adulthood. 3  People who do not have sickle cell disease generally have this type of hemoglobin in their blood cells.ickle cell disease is an inherited blood disorder in which the body produces abnormally shaped red blood cells. In sickle cell disease, the hemoglobin in red blood cells clumps together. This causes red blood cells to become stiff and C-shaped.
A few new pregnancy symptoms will be noticed with the rise and fall of hormonal levels when you are 2 months pregnant. Your waistline is increasing even though you have not put on any significant weight. There is a change in the texture of the hair and skin during pregnancy.
You're most likely to get pregnant if you have sex within a day or so of ovulation (when your ovaries are releasing an egg). This usually happens about 14 days after the first day of your last period. An egg lives for about 12-24 hours after it's released. For you to get pregnant, a sperm must fertilise the egg within this time. Sperm can live for up to seven days inside your body. Guidance from NICE advises that, for the best chance of success, you should have sex every two to three days throughout the month.