Heavy drinking can cause the number of oxygen-carrying red blood cells to be abnormally low. This condition, known as anemia, can trigger a host of symptoms, including fatigue, shortness of breath, and lightheadedness.
The human leukocyte antigen system or complex is a gene complex encoding the major histocompatibility complex proteins in humans. These cell-surface proteins are responsible for the regulation of the immune system in humans. The HLA gene complex resides on a 3 Mbp stretch within chromosome 6p21. HLA genes are highly polymorphic, which means that they have many different alleles, allowing them to fine-tune the adaptive immune system. The proteins encoded by certain genes are also known as antigen
HLA-DQ (DQ) is a cell surface receptor protein found on antigen presenting cells. It is an Î±Î² heterodimer of type MHC Class II. The Î± and Î² chains are encoded by the two loci HLA-DQA1 and HLA-DQB1, respectively, which are adjacent to each other on chromosome 6p 21.3. Both Î±-chain and Î²-chain vary greatly. A person often produces two Î±-chain and two Î²-chain variants and thus 4 isoforms of DQ.