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But denosumab is a first-in-class drug: It's a biologic, which means it will likely be much more expensive than its competitor drugs, some of which are available as cheaper generics. The drug also boasts an extremely convenient dosing regimen -- subcutaneous injection every six months.
â¢ Prolia is an injection that will be given to you by a healthcare professional. Prolia is injected under your skin (subcutaneous). â¢ You will receive Prolia 1 time every 6 months. â¢ You should take calcium and vitamin D as your doctor tells you to while you. receive Prolia. â¢ If you miss a dose of Prolia, you should receive your injection as soon as you. can.