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Prophylaxis of gout flares: If the original colchicine dose was 0.6 mg twice daily, 0.6 mg daily or 0.3 mg twice daily should be given. For an original dose of 0.6 mg daily, the adjusted dose is 0.3 mg daily.Treatment of gout flares: Take 1.2 mg Ã 1 dose of colchicine; at least 3 days should elapse before repeating.rophylaxis of gout flares: If the original colchicine dose were 0.6 mg twice daily, 0.3 mg should be given once daily. For an original dose of 0.6 mg daily, the adjusted dose is 0.3 mg every other day.
Initial dose: 500 to 1000 mg orally once a day. Dose titration: Increase in 500 mg weekly increments as tolerated. Maintenance dose: 2000 mg daily. Maximum dose: 2500 mg daily. Comments: If glycemic control is not achieved with once a day administration of an extended-release product, consider dividing doses.