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Estradiol levels also give important information on the functioning of the ovaries. This can help doctors evaluate menstrual problems, including abnormal bleeding or missing periods. The test may also be used in boys or girls to check for damage or disease of the testes, ovaries, or adrenal glands.
Estradiol is a form of estrogen, a female sex hormone that's produced by the ovaries. Estradiol comes in an oral form, a transdermal skin patch, a vaginal ring, or as a topical gel, spray, or emulsion.stradiol is used to treat and prevent hot flushes in women experiencing menopause. Estradiol gel is also used to treat vaginal dryness, itching, and burning in menopausal women.