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Introduction: Coagulation defects. Description of Coagulation defects. Coagulation defects (medical condition): A general term for a number of conditions that stops the blood from clotting and hence results in ...more. Coagulation defects: See also: Bleeding disorders: Â»Introduction: Bleeding disorders. Â»Symptoms of Bleeding disorders.
Acquired. 1  Liver dysfunction or disease â almost all coagulation factors are produced in the liver; liver disease may result in decreased production of factors. 2  Vitamin K deficiency â the synthesis of several coagulation factors (II, VII, IX, X) requires vitamin K. bleeding disorder may be due to a lack of one or more clotting factors or the result of factors that do not function properly. Deficiency or dysfunction of coagulation factors may have genetic causes (inherited) or may be the result of another disease or condition. The following are a few examples: Inherited.