Install a set of four-bolt steel main caps over the center two crankshaft mains if you're using a two-bolt-main block. Have the block align bored and have the cylinders bored 0.030-inch over. This overbore isn't so much to buy you more displacement as it is to help enhance airflow to feed the extra cubic inches.
Most commonly used fuel is U235, a naturally occurring radioactive isotope of uranium. Occurs naturally at 0.7% of uranium ore, but must be enriched to 3%. Formed in cylindrical pellets (1.5cm long) and stacked in hollow metal rods (4 m long). About 100 rods are bundled together to make a fuel assembly.
Uranium is not the only material used for making atomic bombs. Another material is the element Plutonium, in its isotope Pu-239. Plutonium is not found naturally (except in minute traces) and is always made from Uranium. The only way to produce Plutonium from Uranium is to process U-238 through a nuclear reactor.