Berberine is best taken at doses between 900mg to 2200mg per day taken in 3-4 divided doses. High single doses of Berberine can cause some intestinal update, which is why the dose is split.
Mayan Civilization Rise & Decline (Theories) The Mayan civilization, centered in the tropical lowlands of what is now Guatemala, reached the peak of its power and influence around the sixth century BCE (BC). The Maya excelled at agriculture, pottery, hieroglyph writing, calendar-making and mathematics, and left behind an astonishing amount of impressive architecture and symbolic artwork.
The Postclassic period saw the rise of Chichen Itza in the north, and the expansion of the aggressive K'iche' kingdom in the Guatemalan Highlands. In the 16th century, the Spanish Empire colonized the Mesoamerican region, and a lengthy series of campaigns saw the fall of NojpetÃ©n, the last Maya city in 1697. Classic period rule was centred on the concept of the divine king, who acted as a mediator between mortals and the supernatural realm.