Comments2 Share. This is a list of characters from the Nickelodeon animated comedy series SpongeBob SquarePants. The main characters in the show are SpongeBob SquarePants and his pet snail Gary, SpongeBob's friends Patrick, Squidward and Sandy, and two restaurateur rivals; Mr. Krabs and Plankton.
Technically, Imodium (Loperamide) is an opiate, but it only binds to the mu receptors in the GI tract; and doesn't cross the BBB (Blood Brain Barrier) into the CNS (Central Nervous System) like other opiates do.
An opiate is a substance derived from the poppy plant (which contains opium). Opiates are sometimes called natural since the active ingredient molecules are made by nature, not manufactured by chemical synthesis. Common opiates include morphine and codeine, both made directly from poppy plants. An opioid is a substance (molecule) that is synthetic or partly synthetic, meaning the active ingredients (molecules) are manufactured via chemical synthesis.