Rhabdomyolysis is the breakdown of damaged skeletal muscle. Muscle breakdown causes the release of myoglobin into the bloodstream. Myoglobin is the protein that stores oxygen in your muscles. If you have too much myoglobin in your blood, it can cause kidney damage. About 26,000 cases of rhabdomyolysis are reported in the United States each year.
Cause of Supination. Supination occurs as the foot tilts to the outside. Supination is the rolling of the foot to the outside during normal walking or running motions. The term is usually used in connection with over-supination, which means that the arch of the foot is too high and too much weight is placed on the outside of the foot.
Common signs of supination are high arches and consistent wear on the outside bottom of the shoes. Looking at the wear pattern on the bottom of your running shoes is a good way to check for supination, although additional symptoms are usually present.