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A study done on rats by the National institute on Alcohol Abuse and Alcoholism found that alcohol doesnât prevent azithromycin from killing your bacterial infection. But, drinking alcohol can cause temporary liver damage in some people. That may increase the severity of unpleasant side effects. Alcohol is also dehydrating. A hangover would worsen the nausea, vomiting, and headache that azithromycin may trigger.
Alcohol is thought to decrease the effect of beta-blockers, medications taken by people who have had heart attacks or are being treated for heart failure, chest pain or an abnormal heart rhythm. Therefore, experts recommend that people using beta-blockers avoid drinking alcohol.ombining alcohol and antidepressants may also worsen the symptoms of depression. For people taking a particular class of antidepressants called monoamine oxidase inhibitors (MAOIs), it's best to avoid alcohol entirely, Qato said. Alcohol can interact with these drugs and cause a dangerous rise in blood pressure.