Heavy drinking can cause the number of oxygen-carrying red blood cells to be abnormally low. This condition, known as anemia, can trigger a host of symptoms, including fatigue, shortness of breath, and lightheadedness.
The human leukocyte antigen system or complex is a gene complex encoding the major histocompatibility complex proteins in humans. These cell-surface proteins are responsible for the regulation of the immune system in humans. The HLA gene complex resides on a 3 Mbp stretch within chromosome 6p21. HLA genes are highly polymorphic, which means that they have many different alleles, allowing them to fine-tune the adaptive immune system. The proteins encoded by certain genes are also known as antigen
HLA-C antigen mismatch is associated with an increased risk of mortality compared with 8/8 matches for patients given either myeloablative conditioning (n = 122; RR, 1.40; 95% CI, 1.10-1.78; P = .006) or nonmyeloablative conditioning or RIC (n = 65; RR, 1.40; 95% CI, 1.01-1.95; P = .04).