A consortium comprising the Campbell Collaboration, the EPPI-Centre, Evaluation for Development Policy (EDePo), the International Initiative for Impact Evaluation (3ie),and LSHTM has been awarded the contract for this work.
RNA polymerase is the enzyme that assembles the individual nucleotides to create the RNA strand based on the DNA template. The RNA that is built here can actually be one of three different kinds. You may recall that the three different RNA types are mRNA, rRNA and tRNA. The type that we're concerned with here is mRNA.ere, initiation is the first phase of transcription, during which RNA polymerase attaches to the promoter and begins to build mRNA. The promoter for our keratin gene only exists on one strand of the DNA, which is how we know which strand is the antisense strand.
DNA polymerases are a family of enzymes that carry out all forms of DNA replication. DNA polymerases in general cannot initiate synthesis of new strands, but can only extend an existing DNA or RNA strand paired with a template strand.To begin synthesis, a short fragment of RNA, called a primer, must be created and paired with the template DNA strand.NA polymerase adds a new strand of DNA by extending the 3' end of an existing nucleotide chain, adding new nucleotides matched to the template strand one at a time via the creation of phosphodiester bonds.