Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4000 milligrams per day, and often involve more than one acetaminophen-containing product. 1  VICODIN, VICODIN ES, and VICODIN HP should not be used if you are allergic to hydrocodone or acetaminophen.
Re: Non-Ejaculation. The only way I can see is in my eyes, and understand I am no doctor that a man can orgasm without ejaculation when masturbating and not during other acts is excess. When a man has a allot of sex in a short period of time, he may have a dry orgasm. It is possible, I think every man has had at least one.
However, if premature ejaculation is not an issue, avoid frequent masturbation as it can lead to weak erections due to decreased sex drive or sexual appetite. The more semen discharged so often, the weaker the sex drive even when taking volume pills. There should be a GOOD BALANCE when and not to masturbate.