Nextdoor is the private social network for your neighborhood. On Nextdoor, neighbors create private groups for their neighborhoods where they can ask questions, get to know one another, and exchange local advice and recommendations.
Up-regulation is a process that occurs within a cell triggered by a signal (originating internal or external to the cell), which results in increased expression of one or more genes and as a result the protein(s) encoded by those genes.
Cancer is a disease where regulation of the cell cycle goes awry and normal cell growth and behavior is lost. Cdk (cyclin dependent kinase, adds phosphate to a protein), along with cyclins, are major control switches for the cell cycle, causing the cell to move from G1 to S or G2 to M.