This is of concern for the patients, because a delay in diagnosis and treatment favors the establishment of larvae in muscle tissue and the development of a collagen capsule, which leaves the larvae resistant to drugs (26, 138).pidemiological Investigation Outbreaks of trichinellosis can cause severe harm to the affected group of persons. By definition, a trichinellosis outbreak requires at least one case that must be laboratory confirmed (http://www.med.unipi.it/ict/outbr1.htm).
Tamoxifen may also cause non-cancerous changes in the uterus. In some women, it may increase the risk of blood clots or endometrial cancer (cancer in the lining of the uterus). Remember that each woman's risk factors are different.
Tamoxifen is a selective estrogen receptor modulator. Even though it is an antagonist in breast tissue it acts as partial agonist on the endometrium and has been linked to endometrial cancer in some women. Therefore endometrial changes, including cancer, are among tamoxifen's side effects. With time, risk of endometrial cancer may be doubled to quadrupled, which is a reason tamoxifen is typically only used for 5 years.