The symptoms of peripheral artery disease depend upon the location and extent of the blocked arteries. The most common symptom of peripheral artery disease is intermittent claudication, manifested by pain (usually in the calf) that occurs while walking and dissipates at rest.
John Winthrop (1588-1649) was governor of the Massachusetts Bay Colony-a group of entrepreneurs who left Europe in search of trade opportunities in the New World. Like most members of the Colony, Winthrop was a Puritan. This group claimed that the Church of England was corrupted by selfish leaders and petty squabbles.
A genetically modified organism is any organism whose genetic material has been altered using genetic engineering techniques. GMOs are used to produce many medications and genetically modified foods and are widely used in scientific research and the production of other goods. The term GMO is very close to the technical legal term, 'living modified organism', defined in the Cartagena Protocol on Biosafety, which regulates international trade in living GMOs. A more specifically defined type of GMO is a transgenic organism.. This is an organism whose genetic makeup has been altered by the addition of genetic material from an unrelated organism.