Lymphoid tissue: T-lymphocytes and the Thymus The thymus is a primary lymphoid organ found within the superior mediatinum, behind the upper part of the sternum. This organ is active in children, but at the start of puberty, until old age, it starts to atrophy, producing fewer T-cells.
2. Increased risk of infection. PROGRAF is a medicine that affects your immune system. Prograf can lower the ability of your immune system to fight infections. Serious infections can happen in people receiving Prograf that can cause death. Call your doctor right away if you have symptoms of an infection such as: 1  fever.2  sweats or chills.3  cough or flu-like symptoms. 4  muscle aches. 5  warm, red, or painful areas on your skin.erious infections can happen in people receiving Prograf that can cause death. Call your doctor right away if you have symptoms of an infection such as: 1  fever. 2  sweats or chills. 3  cough or flu-like symptoms. 4  muscle aches. 5  warm, red, or painful areas on your skin.
The U.S. Food and Drug Administration (FDA) recently approved Praluent (alirocumab)â and Repatha (evolocumab)â, the first cholesterol-lowering injection treatments in the new class of PCSK9 inhibitors. Theyâre designed to be used in combination with statin therapy and dietary changes. Praluent and Repatha are for adults with heterozygous familial hypercholesterolemia (HeFH), an inherited condition that causes high levels of LDL cholesterol in the blood, and those with clinical cardiovascular disease.