Of 242 adult allogeneic HSCT patients who received voriconazole, 32 patients developed musculoskeletal pain and underwent subsequent serum fluoride measurement. Of those, 31 patients had a plasma fluoride measurement while on voriconazole. Twenty-nine (93.5%) had elevated fluoride concentrations (> 4 Î¼mol/L).
He was 84. The first CT machine took nine days to scan an object. Processing the information by computer then took 21 hours. Despite such formidable obstacles, researchers were undaunted.Hounsfield conceived the idea for a CAT scanner in 1967. By 1972, he had built a machine that produced detailed cross-sectional images of the brain in less than five minutes.
The first X-ray device was discovered accidentally by the German scientist Wilhelm Roentgen (1845-1923) in 1895. He found that a cathode-ray tube emitted invisible rays that could penetrate paper and wood.The rays caused a screen of fluorescent material several yards away to glow.homas Alva Edison invented an X-ray fluoroscope in 1896. American physiologist Walter Cannon used Edison's device to observe the movement of barium sulfate through the digestive system of animals and, eventually, humans.