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Many women experience symptoms of mental illness during pregnancy. Animals stressed during gestation have smaller offspring. In humans, maternal depression is associated with low birthweight, preterm delivery and other adverse pregnancy outcomes.
USE IN SPECIFIC POPULATIONS. 1  Pregnancy: Opioids cross the placenta and may produce respiratory depression and psycho-physiologic effects in neonates. Chronic maternal use of morphine during pregnancy can affect the fetus with subsequent withdrawal signs. 2  Breast Feeding: Morphine is excreted in breast milk.