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Generally, high doses of niacin are used to control specific diseases. Such high doses must be prescribed by a doctor who will increase the amount of niacin slowly, over the course of 4 to 6 weeks. Take niacin with meals to avoid stomach irritation.
Niacin (also known as vitamin B3 or nicotinic acid) is an organic compound with the formula C 6H 5NO 2 and, depending on the definition used, one of the 20 to 80 essential human nutrients.lushing can be blocked by taking 300 mg of aspirin half an hour before taking niacin, by taking one tablet of ibuprofen per day or by co-administering the prostaglandin receptor antagonist laropiprant. Taking niacin with meals also helps reduce this side effect.