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Many women experience symptoms of mental illness during pregnancy. Animals stressed during gestation have smaller offspring. In humans, maternal depression is associated with low birthweight, preterm delivery and other adverse pregnancy outcomes.
Problems during pregnancy can occur when Rh antibodies from an Rh-sensitized woman cross the placenta and attack the blood of an Rh-positive fetus. The Rh antibodies destroy some of the fetal red blood cells. This causes hemolytic anemia, where red blood cells are destroyed faster than the body can replace them. Red blood cells carry oxygen to all parts of the body. Without enough red blood cells, the fetus will not get enough oxygen.