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Analgesics are drugs designed specifically to relieve pain. There are several types of analgesics: acetaminophen (Tylenol), which is available without a prescription, and a variety of opioid analgesics, which are available only with a prescription.
The two main types of OTC analgesics are NSAIDs (nonsteroidal anti-inflammatory drugs), such as ibuprofen or aspirin and acetaminophen. These medications are commonly used to treat mild to moderate pain associated with headaches, muscle aches, toothaches, colds, flu and menstrual cramps or to reduce fever.