High intakes of vitamin B6 from food sources have not been reported to cause adverse effects [1]. However, chronic administration of 1â6 g oral pyridoxine per day for 12â40 months can cause severe and progressive sensory neuropathy characterized by ataxia (loss of control of bodily movements) [7,29-32].
Accommodative insufficiency (AI) is a condition in which people find it difficult to focus on near objects, to an extent which is unusually poor for their age group.The condition can occur in young people and children, and it is not caused by a problem with the lens of the eye.his means that accommodative insufficiency is different from the disorder known as presbyopia, commonly seen in people over the age of 40. In presbyopia, the lens loses its elasticity and its ability to adapt for near focusing.
Venous insufficiency is a problem with the flow of blood from the veins of the legs back to the heart. It's also called chronic venous insufficiency or chronic venous stasis. Veins have valves that keep the blood moving in one direction-toward the heart. In venous insufficiency, the valves in the veins of the leg don't work right. So fluid pools in the legs. This can lead to problems that include varicose veins.