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If a nerve root is compressed in the spinal column it can send pain signals throughout the nerve, causing symptoms to radiate to other parts of the body. Common sources of upper back problems and shoulder pain include: 1  Degenerative disc disease (DDD) or other intervertebral disc problems. 2  Facet disease. 3  Osteoarthritis. 4  Stenosis. 5  Bone spurs.
Sudden (acute) injury. Injuries are the most common cause of shoulder pain. A sudden (acute) injury may occur from a fall on an outstretched arm, a direct blow to the shoulder, or abnormal twisting or bending of the shoulder. Pain may be sudden and severe. Bruising and swelling may develop soon after the injury.