The most frequent autonomic symptoms associated with multiple system atrophy are a sudden drop in blood pressure upon standing (orthostatic hypotension), urinary difficulties, and erectile dysfunction in men.
The IBM Selectric typewriter was a highly successful model line of electric typewriters introduced by IBM on 31 July 1961.
Finally, in 1867, a Milwaukee, Wisconsin printer-publisher-politician named Christopher Latham Sholes, with assistance from Carlos Glidden and Samuel Soule, patented what was to be the first useful typewriter. He licensed his patent to Remington & Sons of Ilion, New York, a noted American gun maker.