This occurs when a substance passes from the fluid in the tubular lumen through the apical membrane, across the cytosol , and then into the interstitial fluid.
Yes, it's potent stuff. Cat receive it either as an injection or orally. It takes effect in roughly half an hour, lasting about 8 hours before another administration is necessary. Cats usually react negatively to opiates, but buprenorphine is an exception. That's one reason vets use it if they can receive the necessary special certification.
This is often referred to as âtitrating the medication to effectâ. The Benadryl dosage for dogs and cats is 1-2 mg per pound of body weight administered every 8-12 hours as needed. It should be administered orally, approximately one hour prior to a potentially stressful event (a car ride for example).