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Addisonâs disease affects your bodyâs adrenal glands. The adrenal glands are part of the endocrine system. The endocrine system is a group of glands all over your body that produce hormones to regulate your bodyâs processes, including your moods, growth, metabolism, and tissue function.The adrenal glands are located just above your kidneys. They produce hormones that affect how your body responds to stress.In people who have Addisonâs disease, the adrenal glands do not produce enough corticosteroid hormones, such as cortisol and aldosterone.Addisonâs disease is most common among people 30 to 50 years of age, but it can occur at any age and affects men and women equally.hey produce hormones that affect how your body responds to stress. In people who have Addisonâs disease, the adrenal glands do not produce enough corticosteroid hormones, such as cortisol and aldosterone.
Addison's disease is a medical condition in which the adrenal glands stop making hormones important for certain bodily functions. Addison's disease is characterized by weight loss, muscle weakness, fatigue, low blood pressure, and sometimes darkening of the skin in both exposed and non-exposed parts of the body. Other names for Addison's disease include primary adrenal insufficiency and hypocortisolism.