Of 242 adult allogeneic HSCT patients who received voriconazole, 32 patients developed musculoskeletal pain and underwent subsequent serum fluoride measurement. Of those, 31 patients had a plasma fluoride measurement while on voriconazole. Twenty-nine (93.5%) had elevated fluoride concentrations (> 4 Î¼mol/L).
He was 84. The first CT machine took nine days to scan an object. Processing the information by computer then took 21 hours. Despite such formidable obstacles, researchers were undaunted.Hounsfield conceived the idea for a CAT scanner in 1967. By 1972, he had built a machine that produced detailed cross-sectional images of the brain in less than five minutes.
Robert S. Ledley, who invented the whole-body CT scanner, with the first such device, at Georgetown University in 1974. Credit National Biomedical Research Foundation.efore the advent of CT scanning in the early 1970s, radiologists had limited tools. CT scanning gave them not only a far higher resolution than traditional X-rays but also three-dimensional, cross-sectional images to work with, significantly reducing the need for exploratory surgery and its attendant risks.