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If the cells are larger than normal, the histogram curve will be more to right, as in megaloblastic anemia, if the. cells are smaller than normal, the curve will be more to the left as in untreated iron deficiency anemia. After.
Midline shift. Midline shift (arrow) is present in this brain after a stroke (infarct depicted in shaded area). This subdural hematoma/epidural hematoma (arrows) is causing midline shift of the brain. Midline shift is a shift of the brain past its center line. The sign may be evident on neuroimaging such as CT scanning. The sign is considered ominous because it is commonly associated with a distortion of the brain stem that can cause serious dysfunction evidenced by abnormal posturing and failure of the pupils to constrict in response to light.