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1 Blood test. 2  This blood test measures the levels of pregnancy-associated plasma protein-A (PAPP-A) and the pregnancy hormone known as human chorionic gonadotropin (HCG). 3  Abnormal levels of PAPP-A and HCG may indicate a problem with the baby.f your screening test results are positive or worrisome, or you're at high risk of having a baby with Down syndrome, you might consider more testing to confirm the diagnosis. Your health care provider can help you weigh the pros and cons of these tests.
The Pap test can find changes on the cervix caused by HPV. If you are a woman between ages 30 and 65, your doctor might also do an HPV test with your Pap test every five years. This is a DNA test that detects most types of HPV. Another way to tell if you have an HPV infection is if you have genital warts.