In terms of structure, the humerus serves as a connection between the scapula and the elbow, where it links to the two lower arm bones. The humerus bone of the upper arm (the arm in anatomy refers only to the top part of the upper limb i.e. between the elbow and the shoulder).
FDA Approval for Denosumab. Use in Cancer. Denosumab is approved to treat: Giant cell tumor of the bone. It is used in adults and in adolescents whose bones have finished growing. This use is approved for the Xgeva brand of denosumab. Denosumab is approved to prevent and treat: Broken bones and other bone problems caused by solid tumors that have metastasized (spread) to bone. This use is approved for the Xgeva brand of denosumab. Osteoporosis in postmenopausal women who have a high risk of breaking bones. This use is approved for the Prolia brand of denosumab. Denosumab is also approved to increase bone mass in patients who are at high risk of breaking bones.
GilenyaÂ® is a new class of medication called a sphingosine 1-phosphate receptor modulator, which is thought to act by retaining certain white blood cells (lymphocytes) in the lymph nodes, thereby preventing those cells from crossing the blood-brain barrier into the central nervous system (CNS).ilenya was approved by the U.S. Food and Drug Administration (FDA) in 2010 for adults with relapsing forms of MS to reduce the frequency of clinical relapses and to delay the accumulation of physical disability.