1 Germ cells have only half the number of chromosomes as a diploid cell one of each pair. 2  The number of chromosomes is reduced from 46 (23 pairs) to 23 during the process of meiosis. 3  Because they have only half the total chromosomes in a somatic cell, they are termed haploid (n) .II. Meiosis reduces chromosome number from diploid (2n) to haploid (n) 1 diploid cell (2n) cell becomes 4 haploid (n) germ cells (eggs or sperm). During meiosis, chromosomes are replicated once in S phase (just like mitosis) into sister chromatids, but the cell divides twice.
Quinine poisoning presents a unique toxicological syndrome comprising cardiovascular quinidine-like effects, visual loss, CNS signs and cinchonism (tinnitus, paraesthesiae, ataxia).n patients with unconsciousness and ECG changes the diagnosis of quinine poisoning is suggested by fixed dilated pupils (see also differential diagnosis of coma, seizures and arrhythmias). Includes maintenance of the airway and ventilation, IV access and fluids.
Quinine contains two major fused-ring systems: the aromatic quinoline and the bicyclic quinuclidine. Quinine was the first effective Western treatment for malaria caused by Plasmodium falciparum, appearing in therapeutics in the 17th century. It remained the antimalarial drug of choice until the 1940s, when other drugs, such as chloroquine, that have fewer unpleasant side effects replaced it.