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The U.S. Food and Drug Administration yesterday approved a new oral medication for rheumatoid arthritis, or RA. Tofacitinib, brand name Xeljanz (ZEL'jans) , is for patients with moderate to severe rheumatoid arthritis who do not respond well to methotrexate, a disease-modifying antirheumatic drug, or DMARD.
Methotrexate is probably the most important medicine used to treat Rheumatoid Arthritis today. It is the staple of RA treatment since it is effective at reducing disease activity, at least to some degree, for a good percentage of patients.