For more information on becoming a referee and referee courses you can download our information sheet (see âDocumentsâ at the end of this web page). Also, you can contact John Monk (Email: john.monk@amateur-fa.com Tel: 0208 733 2613) who will be pleased to answer any questions you may have about the course.
Genes are found inside choromosomes Genes are located on chromosomes, which are organized structures of DNA and protein. Chromosomes are found in the nucleus of the cell. Actually, a gene itself is coded for by the base sequence (the adenine-thymine and cytosine-guanine sequence) of a DNA strand.
As a subfamily of Argonaute proteins, Piwi is poorly understood compared with Ago subfamily until recent discovery of Piwi protein interacting with piRNA. We did a large scale screening of insect genomes to identify piwi-like genes.Full or partial cDNA sequences were obtained by EST elongation and GENSCAN.IWI domain is of 300 aa in the C-terminal region and structurally similar to RNaseH catalytic domain, which performs a crucial role in slicer activity [6] , [7] and [8] . In animals, Argonaute protein family can be divided into two classes: Ago subfamily and Piwi subfamily.