Zakynthos is a relatively small island so you can drive round it in one day, if you make an early start. Although the roads are generally not very busy, many roads in the north and west of the island are in a poor state of repair. A typically loop round the island is about 200km. Back to top 26.
Low cortisol levels can cause a condition known as Addison's disease. While rare, Addison's disease is an autoimmune disease that causes damage to the adrenal glands. Symptoms may start slowly, but they can be quite serious. Patients with Addison's disease can experience fatigue, muscle loss, weight loss, mood swings and changes to the skin.
Cortisol is a powerful anti-inflammatory and helps the body deal with stress and infections. This defect, in turn, causes a domino-effect producing too much estrogen and not enough thyroid hormones. When the endocrine (hormonal) system is out of balance the end result is low antibodies and a poor immune system.e uncovered a hidden adrenal gland defect that caused an endocrine-immune system imbalance. His research showed this endocrine-immune system dysfunction was caused primarily by poor genetics and over-breeding with a poor nutritional diet of dry kibbles, environmental pollutants, stress and age being secondary factors.