For more information on becoming a referee and referee courses you can download our information sheet (see âDocumentsâ at the end of this web page). Also, you can contact John Monk (Email: john.monk@amateur-fa.com Tel: 0208 733 2613) who will be pleased to answer any questions you may have about the course.
Genes are made up of DNA. Each chromosome contains many genes. A gene is the basic physical and functional unit of heredity. Genes, which are made up of DNA, act as instructions to make molecules called proteins. In humans, genes vary in size from a few hundred DNA bases to more than 2 million bases.
Genetically, HBB locates at 11p15.5 (Bepler et al, 1999) and this locus contains embryonic and adult beta-like globin genes that are ordered as they are expressed during development. High-level expression of the beta-globin gene cluster is regulated by the locus control region (LCR) (Sawado et al, 2003).ecently, we investigated the gene expression profile of anaplastic thyroid cancer cell lines (ACLs) with cDNA microarray analysis (Onda et al, 2004a) and found the novel gene alterations that related to ATC / ACL carcinogenesis.