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The typical dose of Baytril administered to dogs is 2.5 to 10 mg per pound (5 to 20 mg/kg) orally per day. The total daily dose may be given once a day or divided into twice daily doses. In cats, the dose of Baytril should not exceed 5 mg/kg per day orally. The daily dose can be divided and given every 12 hours.
In subacute safety studies, butorphanol was injected subcutaneously to each of six cats at dosages of 0 (saline), 0.4, 1.2 or 2.0 mg/kg, every six hours for six days and continued once daily for a total of 21 days. The only adverse clinical effect observed was pain on injection.