epidermis. 1. the thin protective outer layer of the skin, composed of stratified epithelial tissue. 2. the outer layer of cells of an invertebrate. 3. the outer protective layer of cells of a plant, which may be thickened by a cuticle.[ âepÂ·Éâ²dÉrÂ·mÉs ].pidermis. see skin skin,the flexible tissue (integument) enclosing the body of vertebrate animals. In humans and other mammals, the skin operates a complex organ of numerous structures (sometimes called the integumentary system) serving vital protective and metabolic functions......
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