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Webster Dictionary (0.00 / 0 votes) Rate this definition: Amphi- a prefix in words of Greek origin, signifying both, of both kinds, on both sides, about, around
Familiarity information: AMPHIBIAN used as a noun is uncommon. â¢ AMPHIBIAN (adjective) The adjective AMPHIBIAN has 1 sense: 1. relating to or characteristic of animals of the class Amphibia Familiarity information: AMPHIBIAN used as an adjective is very rare.