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Oxytocin is produced mainly in the hypothalamus, where it is either released into the blood via the pituitary gland, or to other parts of the brain and spinal cord, where it binds to oxytocin receptors to influence behavior and physiology.
In vertebrate anatomy, the pituitary gland, or hypophysis, is an endocrine gland about the size of a pea and weighing 0.5 grams (0.018 oz) in humans. It is a protrusion off the bottom of the hypothalamus at the base of the brain. Oxytocin, most of which is released from the paraventricular nucleus in the hypothalamus. 2  Oxytocin is one of the few hormones to create a positive feedback loop. 3  For example, uterine contractions stimulate the release of oxytocin from the posterior pituitary, which, in turn, increases uterine contractions.