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The typical dose of Baytril administered to dogs is 2.5 to 10 mg per pound (5 to 20 mg/kg) orally per day. The total daily dose may be given once a day or divided into twice daily doses. In cats, the dose of Baytril should not exceed 5 mg/kg per day orally. The daily dose can be divided and given every 12 hours.
Trilostane is the drug of choice for dogs that either do not respond to or do not tolerate mitotane. Although mitotane has been used in cats, it rarely is effective. The treatment of choice in cats is adrenalectomy and supplementation with mineralocorticoids and glucocorticoids.