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antagonism - (biochemistry) interference in or inhibition of the physiological action of a chemical substance by another having a similar structure interference, hinderance, hindrance - the act of hindering or obstructing or impeding
Word Origin & History. antagonize 1630s, to compete with, from Gk. antagonizesthai to struggle against (see antagonist). Meaning to struggle against continuously is recorded from 1742. Jaime suddenly realized the odiousness of his behavior in coming to antagonize another in his own house in broad daylight.