In the same way that the removal of a single domino in the row would interrupt the sequence of toppling, Heinrich suggested that removal of one of the factors would prevent the accident and resultant injury; with the key domino to be removed from the sequence being number 3.
6The Impact of the Opioid Crisis on the Healthcare System. An analysis of the increase in per-patient charges from 2013 to 2015 shows that the rise in charges from. $50,490 to $63,356 for individuals with an opioid abuse or dependence diagnosis exceeds the per-.
Economic Impact of the Opioid Epidemic: 55 billion in health and social costs related to. prescription opioid abuse each year1. 20 billion in emergency department and. inpatient care for opioid poisonings2. Source: Pain Med. 2011;12(4):657-67.1. 2013;14(10):1534-47.2.