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The U.S. Food and Drug Administration yesterday approved a new oral medication for rheumatoid arthritis, or RA. Tofacitinib, brand name Xeljanz (ZEL'jans) , is for patients with moderate to severe rheumatoid arthritis who do not respond well to methotrexate, a disease-modifying antirheumatic drug, or DMARD.
Medicines are the main treatment for rheumatoid arthritis. The types of medicines used depend on how severe your disease is, how fast it is progressing, and how it affects your daily life.edicines are used to: 1  Relieve or reduce pain. 2  Improve daily function. 3  Reduce joint inflammation. 4  Signs of joint inflammation include swelling, tenderness, and limited range of motion. 5  Prevent or delay significant joint damage and deformity. 6  Prevent permanent disability.