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Renal tubular acidosis, a kidney condition that makes the urine more acidic. Kidney stones form more easily in acidic urine. ... Uric acid, calcium oxalate, and cystine stones form more readily in acidic urine, so this prevention strategy hinges on keeping the urine slightly alkaline.
Current research indicates that urine high in calcium, citrates, or oxalates and is acidic predisposes a pet to developing calcium oxalate urinary crystals and stones. Recent studies have shown diets that cause high urine acidity ( urine pH less than 6.5), may predispose dogs to develop this type of bladder stone.