The first symptom of bone cancer is usually pain or tenderness near the cancer. Bone pain is caused by stretching of the periosteum (thick membrane that covers bone) by the cancer, or by stimulation of nerves within the bone. Bone pain may be hard to differentiate from ordinary low back pain or arthritis.
Geometric art is a phase of Greek art, characterized largely by geometric motifs in vase painting, that flourished towards the end of the Greek Dark Ages, circa 900 BC to 700 BC. Its centre was in Athens, and it was diffused amongst the trading cities of the Aegean.
Mannerism is a style of art that was created in the Late Renaissance period, from about 1520 until about 1600.The Mannerist style of painting or sculpture often shows figures that are elongated (made longer) and distorted (made into strange shapes).annerism spread from Italy to France, Germany and Spain. One of the most famous Mannerist painters was El Greco who worked in Spain. Some other artists who worked in the Mannerist style are the French sculptor Jean Goujon, the Dutch painter Abraham Bloemaert and the German painter Bartolomeus Spranger.