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OxyContin: Side Effects. For those whoâve taken more than the prescribed dosage or who donât tolerate opiates, side effects can include clammy skin, shallow breathing, respiratory arrest, circulatory collapse or death. OxyContin Side effects with the prescribed dosage can include: Impaired thinking or reactions. Constipation.
Doctors who prescribe OxyContin anticipate constipation as a side effect of the medication. And because the body does not develop a tolerance for constipation, it usually requires concurrent management, especially in the elderly or other groups with risk factors for this problem.