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The U.S. Food and Drug Administration yesterday approved a new oral medication for rheumatoid arthritis, or RA. Tofacitinib, brand name Xeljanz (ZEL'jans) , is for patients with moderate to severe rheumatoid arthritis who do not respond well to methotrexate, a disease-modifying antirheumatic drug, or DMARD.
You may take rheumatoid arthritis medications alone, but they are often most effective in combination. These are the main types of RA medications: 1  Disease-modifying anti-rheumatic drugs (DMARDs). 2  Biologic response modifiers (a type of DMARD).3  Glucocorticoids.ne of the most important drugs in the arsenal for treating rheumatoid arthritis, DMARDs can often slow or stop the progression of RA by interrupting the immune process that promotes inflammation. However, they may take up to six months to be fully effective.