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Muscular dystrophy is a group of disorders characterized by a progressive loss of muscle mass and consequent loss of strength. The most common form of muscular dystrophy - Duchenne muscular dystrophy - typically affects young boys, but other variations can strike in adulthood. Currently, there is no cure for muscular dystrophy, but certain physical and medical treatments can improve symptoms and slow the disease's progression.
Duchenne muscular dystrophy is much more than a disease of skeletal muscles. Dystrophin is also found in the heart, brain, and smooth muscle. Late-stage cardiac fibrosis can lead to output failure and pulmonary congestion, a common cause of death.uchenne muscular dystrophy clinically manifests in patients aged 3-7 years, with development of lordosis, a waddling gait, and the Gowers sign. Calf pseudohypertrophy follows 1-2 years later. Most patients are wheelchair bound by age 12 years.