Richard Gere as Edward Lewis in Pretty Woman: 'You and I are both similar creatures, Vivian. We both screw people for money.'. Why they spark: Gere's distinguished looks and hard-line attitude blends with Roberts' light hearted, witty style.
An osteoclast is a large multinucleated cell and human osteoclasts on bone typically have five nuclei and are about 150-200 Âµm in diameter. When osteoclast-inducing cytokines are used to convert macrophages to osteoclasts, very large cells that may reach 100 Âµm in diameter occur. These may have dozens of nuclei, and typically express major osteoclast proteins but have significant differences from cells in living bone because of the not-natural substrate.
Overview. An osteoblastoma is an uncommon primary neoplasm of the bone that has clinical and histologic manifestations that are similar to those of an osteoid osteoma; therefore, some consider the 2 lesions to be variants of the same disease, with osteoblastoma representing a giant osteoid osteoma.resentation and natural history. Osteoblastoma is typically seen in the second decade of life, with a male predilection. Approximately 40% of all osteoblastomas are located in the spine. The tumors usually involve the posterior elements, and 17% of spinal osteoblastomas are found in the sacrum.