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Addisonâs disease affects your bodyâs adrenal glands. The adrenal glands are part of the endocrine system. The endocrine system is a group of glands all over your body that produce hormones to regulate your bodyâs processes, including your moods, growth, metabolism, and tissue function.The adrenal glands are located just above your kidneys. They produce hormones that affect how your body responds to stress.In people who have Addisonâs disease, the adrenal glands do not produce enough corticosteroid hormones, such as cortisol and aldosterone.Addisonâs disease is most common among people 30 to 50 years of age, but it can occur at any age and affects men and women equally.hey produce hormones that affect how your body responds to stress. In people who have Addisonâs disease, the adrenal glands do not produce enough corticosteroid hormones, such as cortisol and aldosterone.
A disease that normally affects the lungs is tuberculosis (TB). This infection can also destroy the adrenal glands and cause Addisonâs disease. When primary adrenal insufficiency was identified by Dr. Thomas Addison, TB was the most common culprit of the disease (in 1849).ddisonâs Disease: Symptoms, Causes, Diagnosis & Treatment. The adrenal glands are a part of the bodyâs endocrine system, an interconnected group of glands that work together to secrete hormones (chemical substances) that play an important role in all aspects of our bodyâs processes.