Zakynthos is a relatively small island so you can drive round it in one day, if you make an early start. Although the roads are generally not very busy, many roads in the north and west of the island are in a poor state of repair. A typically loop round the island is about 200km. Back to top 26.
Low cortisol levels can cause a condition known as Addison's disease. While rare, Addison's disease is an autoimmune disease that causes damage to the adrenal glands. Symptoms may start slowly, but they can be quite serious. Patients with Addison's disease can experience fatigue, muscle loss, weight loss, mood swings and changes to the skin.
However, continuous high level of cortisol in your body has negative effects. The condition where your cortisol level in your body is too high over a long period of time is called Cushingâs syndrome. Some of the cause of Cushingâs syndrome are: Chronic stress â Cortisol is also known as the âstress hormoneâ.