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Webster Dictionary (0.00 / 0 votes) Rate this definition: Amphi- a prefix in words of Greek origin, signifying both, of both kinds, on both sides, about, around
Define amphiphilic: of, relating to, or being a compound (such as a surfactant) consisting of molecules having a polar water-soluble group attachedâ¦ of, relating to, or being a compound (such as a surfactant) consisting of molecules having a polar water-soluble group attached to aâ¦