High intakes of vitamin B6 from food sources have not been reported to cause adverse effects [1]. However, chronic administration of 1â6 g oral pyridoxine per day for 12â40 months can cause severe and progressive sensory neuropathy characterized by ataxia (loss of control of bodily movements) [7,29-32].
Accommodative insufficiency (AI) is a condition in which people find it difficult to focus on near objects, to an extent which is unusually poor for their age group.The condition can occur in young people and children, and it is not caused by a problem with the lens of the eye.his means that accommodative insufficiency is different from the disorder known as presbyopia, commonly seen in people over the age of 40. In presbyopia, the lens loses its elasticity and its ability to adapt for near focusing.
Arterial insufficiency occurs when your arteries become narrowed or blocked by an underlying disease or condition. Narrowing of an artery is also called stenosis. This decreases blood flow and oxygen delivery to the cells, tissues and organs being supplied by your arteries.Without adequate blood flow and oxygen, cells and tissues may not function properly and may even begin to die. The most common cause of arterial insufficiency is atherosclerosis, or hardening of the arteries.rterial insufficiency can also be caused by emboli. Emboli are blood clots that travel through the blood until they become lodged in an artery and block blood flow. This can also cause a life-threatening condition, such as a pulmonary embolism. Arterial insufficiency can affect many areas of your body.