Importantly, COMCâs feedback of this outcome information to its participating providers is designed to make it relevant for clinical decision-making, program evaluation, and system redesign.
Anaphylactic shock is the result of a generalized allergic reaction. Septic shock is a result of infections which has progressed to a severe state as in septicemia. Neurogenic shock is a result of severe nerve damage that affects the heart and blood vessels.
Anaphylatoxins are able to trigger degranulation (release of substances) of endothelial cells, mast cells or phagocytes, which produce a local inflammatory response. If the degranulation is widespread, it can cause a shock-like syndrome similar to that of an allergic reaction.