Autoimmune hepatitis is a disease in which the bodyâs immune system attacks liver cells of the same organism. This causes the liver to become inflamed, resulting in hepatitis.
1 Gene mutations that occur after birth. 2  Most gene mutations occur after you're born and aren't inherited. 3  A number of forces can cause gene mutations, such as smoking, radiation, viruses, cancer-causing chemicals (carcinogens), obesity, hormones, chronic inflammation and a lack of exercise.
In these cases, they occur as a result of a mutation on a gene, such as the LMBR1 gene. Mutations are random changes to the DNA base sequence and can happen randomly. Sometimes, mutagens like radiation, UV light and cigarettes can cause mutations, but not all mutations have an outside cause.s polydactyly is usually caused by a random mutation, only one of the parents would be affected and so inbreeding does not increase the likelihood of a child developing polydactyly. If both parents were polydactyls, then the likelihood of the child being affected is 75% but this is not increased by inbreeding.