Surfactant is a complex substance containing phospholipids and a number of apoproteins. This essential fluid is produced by the Type II alveolar cells, and lines the alveoli and smallest bronchioles.
William and Anne Shakespeare had three children. Their first child was Susanna, born a mere six months after the wedding of her parents. She was christened on May 26, 1583, and twins arrived in January, 1585.
The Shakespeare family, then, was in decline as William approached adulthood. It was in the late summer of 1581 that Anne Hathaway, a spinster seven or eight years older than William, discovered she was pregnant with his child.