EXECUTIVE SUMMARY Page ii Denver Metro Chamber of Commerce The Impact of I-70 Congestion on Colorado â Denver to Grand Junction Business Impacts: The lure of Coloradoâs quality of life enhances business recruitment and retention efforts; I-70 congestion may make economic development efforts more difficult.
The development of effective vaccines to prevent paralytic polio was one of the major medical breakthroughs of the 20th century. Two different kinds of vaccine are available, an inactivated (killed) polio vaccine (IPV) and a live attenuated oral polio vaccine (OPV). The presence of neutralizing antibody against polioviruses is considered a reliable correlate of protection against poliomyelitis.
Both vaccines have been used for decades to induce immunity to polio, and to stop the spread of the infection. However, OPV has several advantages; because the vaccine is introduced in the gastrointestinal tract, the primary site of poliovirus infection and replication, it closely mimics a natural infection.