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The U.S. Food and Drug Administration yesterday approved a new oral medication for rheumatoid arthritis, or RA. Tofacitinib, brand name Xeljanz (ZEL'jans) , is for patients with moderate to severe rheumatoid arthritis who do not respond well to methotrexate, a disease-modifying antirheumatic drug, or DMARD.
Several classes of drugs are used to treat rheumatoid arthritis: nonsteroidal antiinflammatory drugs (NSAIDs), disease modifying antirheumatic drugs (DMARDs) (which include both traditional DMARDs and biologic agents), glucocorticoids, and, if needed, pain medications.heumatoid arthritis (RA) is a chronic inflammatory condition affecting the joints. The condition can also affect other tissues throughout the body. The specific causes of rheumatoid arthritis are unknown, though smoking increases the risk of disease and the severity of RA.