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Arava Oral. This medication is used to treat rheumatoid arthritis, a condition in which the body's defense system (immune system) fails to recognize the body as itself and attacks the healthy tissues around the joints. Leflunomide helps to reduce the joint damage/pain/swelling and helps you to move better.
New Arthritis Drug Xeljanz Gets FDA Approval. Nov. 6, 2012 -- The FDA has approved Pfizer's Xeljanz (tofacitinib), a first-of-its-kind treatment for rheumatoid arthritis. Xeljanz is approved for use by patients not helped by methotrexate, the usual first treatment for RA. It's a pill taken twice a day. Xeljanz is a type of drug called a Janus kinase or JAK inhibitor. Blocking JAK mutes the inflammation responses responsible for RA.