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Webster Dictionary (0.00 / 0 votes) Rate this definition: Amphi- a prefix in words of Greek origin, signifying both, of both kinds, on both sides, about, around
Definition of AMPULLA. 1. : a glass or earthenware flask with a globular body and two handles used especially by the ancient Romans to hold ointment, perfume, or wine. 2. : a saccular anatomical swelling or pouch.