The most frequent autonomic symptoms associated with multiple system atrophy are a sudden drop in blood pressure upon standing (orthostatic hypotension), urinary difficulties, and erectile dysfunction in men.
The IBM Selectric typewriter was a highly successful model line of electric typewriters introduced by IBM on 31 July 1961.
It was in this form that Sholes, Glidden and Soule were granted patents for their invention on June 23, 1868 and July 14. The first document to be produced on a typewriter was a contract that Sholes had written, in his capacity as the Comptroller for the city of Milwaukee.