The symptoms of peripheral artery disease depend upon the location and extent of the blocked arteries. The most common symptom of peripheral artery disease is intermittent claudication, manifested by pain (usually in the calf) that occurs while walking and dissipates at rest.
John Winthrop (1588-1649) was governor of the Massachusetts Bay Colony-a group of entrepreneurs who left Europe in search of trade opportunities in the New World. Like most members of the Colony, Winthrop was a Puritan. This group claimed that the Church of England was corrupted by selfish leaders and petty squabbles.
A genetically modified organism (GMO) is any organism whose genetic material has been altered using genetic engineering techniques (i.e., a genetically engineered organism).