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antagonism - (biochemistry) interference in or inhibition of the physiological action of a chemical substance by another having a similar structure interference, hinderance, hindrance - the act of hindering or obstructing or impeding
verb (used with object), antagonized, antagonizing. 1. to make hostile or unfriendly; make an enemy or antagonist of: His speech antagonized many voters. 2. to act in opposition to; oppose. verb (used without object), antagonized, antagonizing.