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If a nerve root is compressed in the spinal column it can send pain signals throughout the nerve, causing symptoms to radiate to other parts of the body. Common sources of upper back problems and shoulder pain include: 1  Degenerative disc disease (DDD) or other intervertebral disc problems. 2  Facet disease. 3  Osteoarthritis. 4  Stenosis. 5  Bone spurs.
For example, inflammation or pressure on a nerve root exiting the spine may cause neck or low back pain. It may also cause pain to radiate from the neck into the shoulder and arm (cervical radiculopathy). Or pain may radiate into the leg and foot (lumbar radiculopathy or sciatic nerve pain).