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If the cells are larger than normal, the histogram curve will be more to right, as in megaloblastic anemia, if the. cells are smaller than normal, the curve will be more to the left as in untreated iron deficiency anemia. After.
This is followed rapidly by egress of cells from the marrow, resulting in an increase in the TBGP and blood neutrophilia. If the demand of cells is high, a shift to the left in the differential count may occur. A left shift is characterized by the appearance of more immature neutrophil forms in the blood.eutrophilia may result from a shift of cells from the marginal to the circulating pool (shift neutrophilia) without an increase in the total blood granulocyte pool (TBGP) or from a true increase in TBGP size (true neutrophilia).