Richard Gere as Edward Lewis in Pretty Woman: 'You and I are both similar creatures, Vivian. We both screw people for money.'. Why they spark: Gere's distinguished looks and hard-line attitude blends with Roberts' light hearted, witty style.
An osteoclast is a large multinucleated cell and human osteoclasts on bone typically have five nuclei and are about 150-200 Âµm in diameter. When osteoclast-inducing cytokines are used to convert macrophages to osteoclasts, very large cells that may reach 100 Âµm in diameter occur. These may have dozens of nuclei, and typically express major osteoclast proteins but have significant differences from cells in living bone because of the not-natural substrate.
Also called osteocartilaginous exostoses, osteochondroma is an overgrowth of cartilage and bone near the end of the bone near the growth plate. This type of overgrowth can occur in any bone where cartilage eventually forms bone. Most commonly, it affects the long bones in the leg, the pelvis, or scapula (shoulder blade). Osteochondroma is the most common benign (noncancerous) bone growth. The lesion usually occurs during skeletal growth between the ages of 10 and 30 years. It affects males and females equally.