Loop & Cross Loop Connection Fishing Knot. Welcome to The FinTalk Fishing Knots details page for tying the Loop & Cross Loop Connection. Follow the directions step by step and practice tying any particular knot over and over until you have it mastered.
Levodopa (L-dopa). A substance used in the treatment of Parkinson's disease. Levodopa can cross the blood-brain barrier that protects the brain. Once in the brain, it is converted to dopamine and thus can replace the dopamine lost in Parkinson's disease.
Administration of dopamine is ineffective in the treatment of Parkinson's disease apparently because it does not cross the blood-brain barrier. However, levodopa, the metabolic precursor of dopamine, does cross the blood-brain barrier, and presumably is converted to dopamine in the brain. This is thought to be the mechanism whereby levodopa relieves symptoms of Parkinson's disease.