Hypothetically, if the threshold is normally -60mV, but now we have too much calcium on board, our threshold is now -50mv. That is a difference of 40mV that the cell has to account for in order to depolarize. In skeletal muscle, this can cause weakness, fatigue, etc. Too little calcium will cause the threshold to become more negative (gets closer to the resting membrane potential).
OK, this is probably going to come with you laughing at me... Once in a while I wake up with the back of my head sweating, and it`s more common when I take a nap during the day.
Itâs not clear whether this could lead to night sweats, but one study in Human Kinetics did find that night sweats can be a sign of overtraining. (Your perspiration can be more telling than you think. Discover What You Can Learn from Your Sweat .). The bottom line: If you wake up in a pool of sweat almost every night, or if your alarm sounds and youâre soaked through your pajamas, you should see your doctor, says Dr. Mold.