More directly relevant is the level of kidney function. In patients with poor kidney function or those on dialysis, the drug can accumulate to levels above the theraputic range. There are several reports of abnormal movements (myoclonus) when this occurs. Common practice is to start at a lower dose in these patients.
Bleach (Nirvana album) Bleach is the debut studio album by American rock band Nirvana, released on June 15, 1989 by Sub Pop. The main recording sessions took place at Reciprocal Recording in Seattle, Washington between December 1988 and January 1989.
Everman joined Nirvana in February 1989 as a second guitarist. He is listed as being second guitarist on Nirvana's Bleach and appears on the cover, but did not actually play on any of the tracks. Nirvana founder Kurt Cobain said the credit was a token of thanks to Everman for paying a fee of $606.17 to record the album.