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Whatâs more, aside from increased level of ammonia in the blood, other symptoms also can be induced such as muscle weakness, fatigue, lethargy and so on. In addition, if left untreated, elevated blood ammonia can affect brain tissue, leading to symptoms such as confusion and delirium.
Ornithine transcarbamylase deficiency is an inherited disorder that causes ammonia to accumulate in the blood. Ammonia, which is formed when proteins are broken down in the body, is toxic if the levels become too high. The nervous system is especially sensitive to the effects of excess ammonia.