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Posts. 148. elguapo, It comes with that warning because diphenhydramine, the active ingredient in Unisom, can make urination more difficult. A guy with an enlarged prostate is already going to have difficulty urinating and diphenhydramine would just add to the problem.
Ingredients Contained In This Product. Kirkland Sleep Aid â Product Description. Doxylamine Succinate is the sole active ingredient in Kirkland Sleep Aid. Sometimes labelled as Unisom, it is a sleep-inducing substance that is designed to allow the user to fall asleep faster and enjoy more restful, undisturbed sleep.