1. Exogenous Causes. Dry Skin is the most common and obvious cause of itchy soles of the feet. The most likely cause is a lack of moisture in the skin. This affects the elderly more than the younger members of the population and it is found more frequently during the colder winter months.
In molecular genetics, an open reading frame (ORF) is the part of a reading frame that has the potential to code for a protein or peptide. An ORF is a continuous stretch of codons beginning with a start codon (usually AUG) and ending with a stop codon (usually UAA, UAG or UGA). An AUG codon within the ORF (not necessarily the first) may indicate where translation starts.
Von Willebrand disease (vWD) (/ËfÊnËvÉªlÉ¨brÉËnt/) is the most common hereditary coagulation abnormality described in humans, although it can also be acquired as a result of other medical conditions.he von Willebrand factor is qualitatively normal and genetic testing of the von Willebrand gene and vWF protein reveals no mutational alteration. The defect lies in the qualitatively altered glycoprotein Ib (GPIb) receptor on the platelet membrane which increases its affinity to bind to the von Willebrand factor.