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Posts. 148. elguapo, It comes with that warning because diphenhydramine, the active ingredient in Unisom, can make urination more difficult. A guy with an enlarged prostate is already going to have difficulty urinating and diphenhydramine would just add to the problem.
If you are taking Unisom SleepMelts TM or SleepMinis TM, please take two. When taking Unisom Liquid, use the measuring cup provided to get the correct dosage (30mL). Always refer to the directions located on the back label of all Unisom products. We do not recommend any other dosage amounts.