â¢ AUTOIMMUNE DISEASE (noun). The noun AUTOIMMUNE DISEASE has 1 sense: 1. any of a large group of diseases characterized by abnormal functioning of the immune system that causes your immune system to produce antibodies against your own tissues.
The initiation of cell transformation is generally associated with genetic alterations in normal cells that lead to the loss of intercellular-and/or extracellular-matrix- (ECM-) mediated cell adhesion.ancer afflicts an organ or a tissue by inducing abnormal and uncontrolled division of cells that either constitute it or migrate to it. At the cellular level, this is caused by genetic alterations in networks that regulate cell division and cell death.
When the normal mechanisms for regulating growth of cells in our body are disturbed then cells begin to grow in an uncontrolled fashion. This situation arises when the genes that regulate growth of normal cells are damaged giving rise to abnormal genes with disturbed functions.