Symptoms include shaking, tremor, slowness of movement, stiffness in the arms, legs, and trunk, and balance problems. Doctors diagnose it by taking a medical history and doing a neurological exam. A blood test could help doctors diagnose and treat the disease earlier. Many teams are working on such tests.
This number is the cycle in which Earth Time and Vanadiel Time repeats. There are 56 Days in 8 weeks in order for the same Vanadiel day to start over at JST (0:00:00). Also there are 25 Vanadiel days in 1 Earth Day. 25/8 = 24, with a 1 day remainder. That remainder must carry over to the next day, which each Vanadiel week shifts to the next Earth 24 Hour period.
Onset of effects occurs within 30-60 minutes after taking Concerta. After that, duration of action lasts from 8-12 hours. And the average times to reach peak plasma concentrations across all doses of Concerta occur between 6-10 hour s. The average half-life for Concerta in adults is about 3.5 hours.