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Coagulase is a protein enzyme produced by several microorganisms that enables the conversion of fibrinogen to fibrin. In the laboratory, it is used to distinguish between different types of Staphylococcus isolates.oagulase is tightly bound to the surface of the bacterium S. aureus and can coat its surface with fibrin upon contact with blood. The fibrin clot may protect the bacterium from phagocytosis and isolate it from other defenses of the host.
Coagulation is the means by which we stop bleeding (hemostasis) and form blood clots after injury to blood vessels. Essentially, coagulation is clotting of the blood, an extremely important process. How our bodies coagulate blood has been a matter of intensive study, since some people with certain diseases like hemophilia are unable to do so.