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Symptoms of Lymphoma in Cats. Cats with lymphoma may demonstrate only very vague problems. Progressive lack of appetite, lethargy and weight loss are most common. Depending on which organs are affected, other signs such as chronic diarrhea, vomiting and difficulty in breathing may occur.
Enlarged lymph nodes or âglandsâ are the most common symptom of lymphoma. Dogs still may feel normal at this point in the disease or they may have vague symptoms. Nonspecific signs may include: 1  Distended abdomen. 2  Lethargy.3  Coughing. 4  Shortness of breath. 5  Fever.6  Poor appetite.nlarged lymph nodes or âglandsâ are the most common symptom of lymphoma. Dogs still may feel normal at this point in the disease or they may have vague symptoms. Nonspecific signs may include: 1  Distended abdomen. 2  Lethargy.