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Signs and symptoms. Osteoarthritis most often occurs in the hands (at the ends of the fingers and thumbs), neck, lower back, knees, and hips. The main symptom is pain, causing loss of ability and often stiffness.
Osteoarthritis is a degenerative joint disease, meaning that the cartilage covering the ends of the bones that form a joint gradually deteriorates. 1  Mechanical wear and tear that builds up over time is the most common cause of osteoarthritis, but it can also develop due to an injury. When an injury changes the alignment of a joint, it can damage cartilage more rapidly. In the hands, this damage causes enlarged joints and crooked fingers.