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Posts. 148. elguapo, It comes with that warning because diphenhydramine, the active ingredient in Unisom, can make urination more difficult. A guy with an enlarged prostate is already going to have difficulty urinating and diphenhydramine would just add to the problem.
Occasionally, there may be sales or coupons that apply to Unisom depending on the local store, but in general, there are no discounts available for purchasing a large supply of Unisom at once. Does Unisom Work? The problem with Unisom is that it does work, if you have an extremely loose definition of what you are expecting from a sleep aid product. Since Unisom contains such a heavy sedative, users of Unisom are almost certain to drop off to sleep directly.