Virtual Design and Construction is the management of integrated multi-disciplinary performance models of design-construction projects, including the product, work processes and organization of the design - construction - operation team in order to support explicit and public business objectives. The theoretical basis of VDC includes: Engineering modeling methods: product, organization, process Analysis methods - Model-based design: including quantities, schedule, cost, 4D interactions and proces
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Proinsulin is the prohormone precursor to insulin made in the beta cells of the islets of Langerhans, specialized regions of the pancreas. In humans, proinsulin is encoded by the INS gene. The islets of Langerhans only secrete between 1% and 3% of proinsulin intact.