1. Exogenous Causes. Dry Skin is the most common and obvious cause of itchy soles of the feet. The most likely cause is a lack of moisture in the skin. This affects the elderly more than the younger members of the population and it is found more frequently during the colder winter months.
In molecular genetics, an open reading frame (ORF) is the part of a reading frame that has the potential to code for a protein or peptide. An ORF is a continuous stretch of codons beginning with a start codon (usually AUG) and ending with a stop codon (usually UAA, UAG or UGA). An AUG codon within the ORF (not necessarily the first) may indicate where translation starts.
The structural organization of GEP genes is better understood in terms of open reading frames (ORFs). In biology, an ORF or coding sequence of a gene begins with the start codon, continues with the amino acid codons, and ends at a termination codon. However, a gene is more than the respective ORF, with sequences upstream of the start codon and sequences downstream of the stop codon. Although in GEP the start site is always the first position of a gene, the termination point does not always coincide with the last position of a gene.