â¢ AUTOIMMUNE DISEASE (noun). The noun AUTOIMMUNE DISEASE has 1 sense: 1. any of a large group of diseases characterized by abnormal functioning of the immune system that causes your immune system to produce antibodies against your own tissues.
The initiation of cell transformation is generally associated with genetic alterations in normal cells that lead to the loss of intercellular-and/or extracellular-matrix- (ECM-) mediated cell adhesion.ancer afflicts an organ or a tissue by inducing abnormal and uncontrolled division of cells that either constitute it or migrate to it. At the cellular level, this is caused by genetic alterations in networks that regulate cell division and cell death.
Every day old cells wear out and are removed by the body. From the remaining cells, new cells are formed by cell division. Good health requires a balance of new cells replacing old cells. Some mutations in the cellâs DNA cause the old cells to be abnormal and to keep on living. These abnormal cells pile up. When the pile of cells grows and does not stop (because of the mutation), it is a cancer.