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Posts. 148. elguapo, It comes with that warning because diphenhydramine, the active ingredient in Unisom, can make urination more difficult. A guy with an enlarged prostate is already going to have difficulty urinating and diphenhydramine would just add to the problem.
However, your feedback is important to us. Nocturia, or nocturnal polyuria, is the medical term for excessive urination during the night. During sleep time, your body produces less urine that is more concentrated. This means that most people donât need to wake up during the night to urinate and can sleep uninterrupted for six to eight hours.