Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum subspecies pallidum. The signs and symptoms of syphilis vary depending in which of the four stages it presents (primary, secondary, latent, and tertiary). The primary stage classically presents with a single chancre (a firm, painless, non-itchy skin ulceration) but there may be multiple sores.
Asia Minor is a geographic region in the south-western part of Asia comprising most of what is present-day Turkey. The earliest reference to the region comes from tablets of the Akkadian Dynasty (2334-2083 BCE) where it is known as âThe Land of the Hatti â and was inhabited by the Hittites.
In a strict sense , the middle east is the original Asia , and the name was later applied to a greater and greater expanse of land as awareness of those areas grew . in the Roman period Asia was a specific province in what is now Turkey , and eventually that whole area became known as  Asia Minor / Mikrasia  ( meaning  little / near-asia  as ...