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The plants belong to the scientific order of Polemoniales and the Solanaceae family of plants. The nightshades include numerous vegetables: potatoes, tomatoes, sweet peppers, hot peppers, eggplant, tomatillos, tamarillos, pepitos, pimentos, paprika, and cayenne peppers.
Vegetables from the Solanaceae family produce alkaloids to ward off insects and prevent them from eating the plant. Humans can be sensitive to them as well, but many people consume nightshade vegetables without noticing any adverse effects.