More directly relevant is the level of kidney function. In patients with poor kidney function or those on dialysis, the drug can accumulate to levels above the theraputic range. There are several reports of abnormal movements (myoclonus) when this occurs. Common practice is to start at a lower dose in these patients.
Bleach (Nirvana album) Bleach is the debut studio album by American rock band Nirvana, released on June 15, 1989 by Sub Pop. The main recording sessions took place at Reciprocal Recording in Seattle, Washington between December 1988 and January 1989.
By Mary Kyne. In June 1845 reports began to come from Europe that a new blight had been noticed in Belgium. It is not known for certain where it came from but it had been in America from 1843 and may have been imported with guano (fertiliser) from South America.