Hypothetically, if the threshold is normally -60mV, but now we have too much calcium on board, our threshold is now -50mv. That is a difference of 40mV that the cell has to account for in order to depolarize. In skeletal muscle, this can cause weakness, fatigue, etc. Too little calcium will cause the threshold to become more negative (gets closer to the resting membrane potential).
OK, this is probably going to come with you laughing at me... Once in a while I wake up with the back of my head sweating, and it`s more common when I take a nap during the day.
If you believe your symptoms are harmless, cooling pillows have been shown to help achieve a good nights sleep. More serious causes of night sweats can be menopause, an acute infection, tuberculosis (T.B.) and â when associated with fatigue and weight loss may point to cancer.