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Gadolinium contrast medium is generally very safe. Side effects or reactions are uncommon, but can occur. In patients with normal kidney function, most of the gadolinium contrast medium injected (over 90%) is passed out in the urine within 24 hours.
This article reviews the current status of GBC agents as nephrotoxins and causes of NSF and provides opinions on how to use these agents in patients with underlying kidney disease. Magnetic resonance imaging (MRI) scans are significantly enhanced by use of gadolinium-based contrast (GBC) agents. They also have the advantage of avoiding iodinated radiocontrast agents, which have significant overall toxicity.