The level of digoxin in your blood that's needed for it to be effective is quite close to the blood level that can cause unwanted effects. While taking digoxin you'll also need to have regular blood tests to monitor your kidney function and the levels of salts (electrolytes), particularly potassium, in your blood. If the level of potassium in your blood drops too low (hypokalaemia) the risk of digoxin side effects is increased. You should make sure you include plenty of fresh fruit and vegetables in your diet to avoid this.
George Washington had no children of his own, but he had two step-children, the children of his wife Martha Custis and her first husband Daniel Custis. They were John Jacky Parke Custis (27 November 1754 - 5 November 1781 ) and Martha Patsy Parke Custis (December 1755- 19 June 1773).
John Parke Custis (known as Jacky when younger, and Jack as he got older) was around four years old when his mother Martha married George Washington. Custis was one of the two surviving children of Martha Washington's first marriage to Daniel Parke Custis. As a result, George Washington became Jacky's legal guardian. Following the death of his sister Martha Parke Custis in 1773, Custis became the sole heir of the Custis estate.