1. Treat Symptoms. 1  Most styes go away on their own in about a week. 2  Apply a warm compress for 5 to 10 minutes several times a day. Use a clean washcloth or towel soaked in warm water.
Concomitant Use of Ibuprofen and Aspirin : Ibuprofen can interfere with the antiplatelet effect of low dose aspirin (81 release aspirin (not enteric coated) and take a single dose of ibuprofen 400 mg when ibuprofen 400 mg is do , and 12 hours after aspirin.
Depending on what painkiller, and why. If it's another NSAID, you should wait around 4 to 6 hours unless the dose of ibuprofen was low e.g. 200 mg. As for ibuprofen, if the pain didn't lessen after taking a dose of ibuprofen, if no stomach ache I would prefer one taking more ibuprofen up to maximum of 800 mg in total.