Ken Jones, a leading amateur microscopist, specialises in video-filming pond-life. One of his videos captures the enigmatic and graceful movement of Volvox, and he has kindly allowed us to show some extracts from his film on this page. A single Volvox colony spins through the dark waters of a pond. Daughter cells are just visible inside. Micscape Editor's note.
Heart, liver, or kidney disease. Sometimes swelling can indicate a problem such as heart, liver, or kidney disease. Ankles that swell in the evening could be a sign of retaining salt and water because of right-sided heart failure. Kidney disease can also cause foot and ankle swelling.
Also try a low salt diet for a bit and see if it helps. If your legs are red as well as swollen, I would see my dr immediately. Several things can cause this, none of which are the Oxycontin. A lot of sitting and/or posture are among the many causes.