How drugs affect people depends on lots of things: the kind of drug taken; how much is taken; how often someone uses it; how quickly it gets to the brain; what other drugs, food, or substances are taken at the same time; the person's body size, shape, and chemistry; Although substances can feel good at first, they can do a lot of harm to the body and brain. Drinking alcohol, smoking or using tobacco, taking illegal drugs, even sniffing glue all damage the human body.
Introduction. Granuloma annulare is a long-lasting rash that looks like a ring of small red or skin-coloured bumps. The rash usually appears over the backs of your forearms, hands or feet. It tends to affect children and young adults, and is slightly more common in females.
A granuloma may resmble a foreign body reaction as with a splinter or, more to the point, from an injection of a substance, such as with dermal fillers used for cosmetic purposes to improve facial lines and enhance contour. True granulomas with any filler are quite rare.