Amiloride and triamterene interfere with the sodium-potassium exchange at the distal convoluted tubule of the kidney. Spironolactone acts as an aldosterone antagonist. Aldosterone promotes sodium and water retention. By blocking the actions of aldosterone, spironolactone prevents increases in fluid volume.
Shelf life: If properly sealed or wrapped the all-purpose flour should last safely on your shelf for 10-15 months. If refrigerated, then up to 24 months. You can make your own self-rising flour by adding 1 1/2 teaspoons baking soda and a half teaspoon of salt to one cup of All Purpose Flour.Instant Flour is wheat flour in which barley flour has been added.ou can make your own self-rising flour by adding 1 1/2 teaspoons baking soda and a half teaspoon of salt to one cup of All Purpose Flour. Instant Flour is wheat flour in which barley flour has been added.
Place the remaining 11 ounces of flour, remaining yeast, and all the salt into the bowl of a stand mixer, and add the pre-ferment from the refrigerator. Using the dough hook attachment, knead the mixture on low for 2 to 3 minutes just until it comes together.