Metallosis often causes the following symptoms: Cardiomyopathy (heart problems), including heart failure. Depression, anxiety and other mental problems. Visual impairment that may lead to blindness. Cognitive impairment. Nerve problems. Thyroid problems. Auditory impairment that may lead to deafness.
Coordination refers to the coordinate covalent bonds (dipolar bonds) between the ligands and the central atom. Originally, a complex implied a reversible association of molecules, atoms, or ions through such weak chemical bonds. As applied to coordination chemistry, this meaning has evolved.
1 Coordination compounds are complexes that consist of one or more central atoms or ions with one or more attached molecules. 2  The central atom is called a metal, and is a Lewis Acid;  The attached ions are ligands, and are Lewis Bases;