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Posts. 148. elguapo, It comes with that warning because diphenhydramine, the active ingredient in Unisom, can make urination more difficult. A guy with an enlarged prostate is already going to have difficulty urinating and diphenhydramine would just add to the problem.
Vitamin B6 is often helpful for moms-to-be with mild to moderate nausea. Antihistamines have also been used to treat nausea and vomiting in pregnancy. Your practitioner may recommend doxylamine, an antihistamine that's available as a sleeping pill under the brand name Unisom Nighttime Sleep-Aid.