Close enough for you to realize that it is the largest bear you have ever seen. You crouch frozen, adrenaline coursing through you like a rushing river. You are transfixed by the size of this beast. As the bear passes, its odor fills your nostrils, the rotten-flesh stench of a carnivore.
Sucralose also causes swelling of the liver and kidneys, calcification of the kidney, fertility issues in male rates, and gastrointestinal problems in pregnant rats. If you experience kidney pain, cramping, swelling, an irritated bladder, or blood in your urine after using sucralose in Splenda, stop use immediately.
1 When the drug is used with other drugs that may harm the kidneys, such as cyclosporin, the antibiotics gentamicin and amikacin, or the antifungal drug amphotericin B, blood levels of tacrolimus may be increased.2  Careful kidney monitoring is essential when tacrolimus is given with any drug that might cause kidney damage.n addition to being used to prevent organ rejection, immunosuppressant drugs are also used to treat such severe skin disorders as psoriasis and such other diseases as rheumatoid arthritis, Crohn's disease (chronic inflammation of the digestive tract) and patchy hair loss (alopecia areata).