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To determine whether breast cancer cells contain hormone receptors, doctors test samples of tumor tissue that have been removed by surgery. If the tumor cells contain estrogen receptors, the cancer is called estrogen receptor positive (ER positive), estrogen sensitive, or estrogen responsive.
Estradiol is a type of estrogen, the major sex hormone in women. It is secreted by the ovarian follicles. As the follicles grow and develop each month, they produce estradiol. This sets the rest of the reproductive cycle in motion. A blood test to check estradiol levels is one of the most common fertility tests. One reason to have your estradiol levels checked is to determine your ovariesâ ability to produce eggs (which is known as ovarian reserve). It can also help to determine if your follicle stimulating hormone (FSH) test was accurate or not.