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Posts. 148. elguapo, It comes with that warning because diphenhydramine, the active ingredient in Unisom, can make urination more difficult. A guy with an enlarged prostate is already going to have difficulty urinating and diphenhydramine would just add to the problem.
How they can cause insomnia: Alpha-blockers are linked to decreased REM (rapid eye movement) sleep â the stage of sleep when people dream â and daytime sedation or sleepiness. The proportion of REM sleep drops markedly in old age, and people deprived of REM sleep can experience memory problems.