Hypothetically, if the threshold is normally -60mV, but now we have too much calcium on board, our threshold is now -50mv. That is a difference of 40mV that the cell has to account for in order to depolarize. In skeletal muscle, this can cause weakness, fatigue, etc. Too little calcium will cause the threshold to become more negative (gets closer to the resting membrane potential).
OK, this is probably going to come with you laughing at me... Once in a while I wake up with the back of my head sweating, and it`s more common when I take a nap during the day.
Sweating occurs when the sweat glands in your skin secrete a salty fluid called sweat, or perspiration. Sweating is a normal function that serves to cool your body, often in hot or humid environments or when you exercise. Excessive sweating may be a symptom of an underlying disease, disorder or condition.