More directly relevant is the level of kidney function. In patients with poor kidney function or those on dialysis, the drug can accumulate to levels above the theraputic range. There are several reports of abnormal movements (myoclonus) when this occurs. Common practice is to start at a lower dose in these patients.
Bleach (Nirvana album) Bleach is the debut studio album by American rock band Nirvana, released on June 15, 1989 by Sub Pop. The main recording sessions took place at Reciprocal Recording in Seattle, Washington between December 1988 and January 1989.
Cartoon Network's Adult Swim began airing dubbed episodes of Bleach in the United States that Fall, and Hulu later began to stream subtitled versions of the anime a week after each episode aired in Japan. Viz Media has also released each of the Bleach feature films in English.