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Posts. 148. elguapo, It comes with that warning because diphenhydramine, the active ingredient in Unisom, can make urination more difficult. A guy with an enlarged prostate is already going to have difficulty urinating and diphenhydramine would just add to the problem.
Doxylamine succinate is clinically proven and FDA approved to help you fall asleep 33% faster. 1 Unisom SleepTabs is the only leading over-the-counter sleep-aid brand that uses this ingredient.