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Signs and symptoms. Osteoarthritis most often occurs in the hands (at the ends of the fingers and thumbs), neck, lower back, knees, and hips. The main symptom is pain, causing loss of ability and often stiffness.
The primary symptoms associated with knee osteoarthritis include: 1  pain in the knee, which can be mild, moderate, or severe. 2  stiffness of the knee joint. 3  limited range of motion in the knee, you can't bend it as far as is normal.  localized swelling of the knee.