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To determine whether breast cancer cells contain hormone receptors, doctors test samples of tumor tissue that have been removed by surgery. If the tumor cells contain estrogen receptors, the cancer is called estrogen receptor positive (ER positive), estrogen sensitive, or estrogen responsive.
Estrogen is essential to a woman's physical and psychological well-being, impacting everything from reproductive ability to bone strength. The hormone affects a variety of different organs, including the reproductive tract; urinary tract; heart and blood vessels; bones; breasts; skin; hair; mucous membranes; pelvic muscles; and the brain.