Muscle, nerve, and joint weakness, and deterioration result. It is not uncommon to see the patient with severe, uncontrolled pain progressively deteriorate due to muscle atrophy and contractures and go from cane to walker to wheelchair. An unappreciated complication of deconditioning and immobility is obesity.
Opsins are a group of light-sensitive proteins found in photoreceptor cells of the retina. Five classical groups of opsins are involved in vision, mediating the conversion of a photon of light into an electrochemical signal, the first step in the visual transduction cascade. Another opsin found in the mammalian retina, melanopsin, is involved in circadian rhythms and pupillary reflex but not in image-forming.
Operations Security, or OPSEC, is the process by which we protect unclassified information that an adversary could use against us. OPSEC challenges us to look at ourselves through the eyes of the adversary.