Definition is a rhetorical mode that can be used in something smaller or shorter than a full paper. You can use extended definition for several paragraphs only in a paper of much greater length. You also can add to a paper a one-paragraph definition--like a brief encyclopedia definition.
Depending upon location, neural crest cells give rise to most of the peripheral nervous system, as well as various non-neural tissues, like craniofacial bone and cartilage, the thymus and parathyroid glands, and the cardiac outflow tract â in short, all of the tissues that are affected in DiGeorge syndrome.
Transduction of MEFs and BMDMs with replication-incompetent retroviruses encoding only the mitochondria-targeted HSV-1 UL12 M185 gene product was sufficient to cause mitochondrial hyperfusion, nucleoid enlargement and mtDNA loss, indicative of mtDNA stress (Fig. 4d and Extended Data Fig.e next examined the involvement of the cytosolic DNA sensor cGAS in mtDNA stress signalling, as it mediates ISG expression in response to exogenous and endogenous immunostimulatory DNA species. Knockdown of cGAS in Tfam+/â MEFs or TFAM depletion in cGasâ/â MEFs largely abrogated ISG expression (Fig. 2a).