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Fibrous Pericardium. Continuous with the central tendon of the diaphragm, the fibrous pericardium is made of tough connective tissue and is relatively non-distensible. This rigidity prevents rapid overfilling of the heart, but can have several serious clinical consequences (see cardiac tamponade).
The Normal Pericardium. The pericardium is a relatively avascular fibrous sac that surrounds the heart. It consists of 2 layers: the visceral and parietal pericardium. The visceral pericardium is composed of a single layer of mesothelial cells that are adherent to the cardiac epicardium.he Normal Pericardium. The pericardium is a relatively avascular fibrous sac that surrounds the heart. It consists of 2 layers: the visceral and parietal pericardium. The visceral pericardium is composed of a single layer of mesothelial cells that are adherent to the cardiac epicardium.