Leptin is produced primarily in the adipocytes of white adipose tissue. It also is produced by brown adipose tissue, placenta (syncytiotrophoblasts), ovaries, skeletal muscle, stomach (the lower part of the fundic glands), mammary epithelial cells, bone marrow, gastric chief cells and P/D1 cells.
The fuel filter, in a 2008 Ford fusion, is located inside of the fuel tank. Drain the fuel from the fuel tank. Remove the fuel filter plate. The fuel filter will slide out. Reverse the process to install the new fuel filter. The fuel filter, in a 2008 Ford fusion, is located inside of the fuel tank. Drain the fuel from the fuel tank.
Keep in mind that last year, Ford was compelled to re-rate the fuel economy of the Fusion Hybrid, down from 47 mpg combined to 42 mpg combined, after the EPA revisited its fuel-economy procedures. The base engine in the Fusion S and SE is a 2.5-liter four-cylinder. It's combined with a six-speed automatic, and generates fuel economy figures of 22 miles per gallon city, 34 miles per gallon highway, or 26 mpg combined.