â¢ AUTOIMMUNE DISEASE (noun). The noun AUTOIMMUNE DISEASE has 1 sense: 1. any of a large group of diseases characterized by abnormal functioning of the immune system that causes your immune system to produce antibodies against your own tissues.
The initiation of cell transformation is generally associated with genetic alterations in normal cells that lead to the loss of intercellular-and/or extracellular-matrix- (ECM-) mediated cell adhesion.ancer afflicts an organ or a tissue by inducing abnormal and uncontrolled division of cells that either constitute it or migrate to it. At the cellular level, this is caused by genetic alterations in networks that regulate cell division and cell death.
Cancer is caused by changes (mutations) to the DNA within cells. The DNA inside a cell is packaged into a large number of individual genes, each of which contains a set of instructions telling the cell what functions to perform, as well as how to grow and divide.Errors in the instructions can cause the cell to stop its normal function and may allow a cell to become cancerous. gene mutation can instruct a healthy cell to: 1  Allow rapid growth. 2  A gene mutation can tell a cell to grow and divide more rapidly. 3  This creates many new cells that all have that same mutation. 4  Fail to stop uncontrolled cell growth.