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To determine whether breast cancer cells contain hormone receptors, doctors test samples of tumor tissue that have been removed by surgery. If the tumor cells contain estrogen receptors, the cancer is called estrogen receptor positive (ER positive), estrogen sensitive, or estrogen responsive.
Test Overview. An estrogen test measures the level of the most important estrogen hormones in a blood or urine sample. It measures estradiol, estriol, and estrone. Estradiol is the most common type of estrogen measured for nonpregnant women. The amount of estradiol in a woman's blood varies throughout her menstrual cycle.