GERD may lead to Barrett's esophagus, a type of intestinal metaplasia, which is in turn a precursor condition for esophageal cancer. The risk of progression from Barrett's to dysplasia is uncertain, but is estimated at about 20% of cases.
The Newell Manufacturing Company was founded in Ogdensburg, New York in 1903 as a manufacturer of metal curtain rods.
The Sharpie also became the first pen-style permanent marker. In 1990 Sharpie was acquired by The Newell Companies (later Newell Rubbermaid) as part of Sanford, a leading manufacturer and marketer of writing instruments.