Tensor tympani- The tensor tympani is the larger of the two muscles of the auditory canal, the other being stapedius. The muscle functions to dampen down sounds such as chewing. It arises from the cartilaginous portion of the eustachian tube as well as the adjacent section of the greater wing of the sphenoid bone.
A nonsense mutation in the leptin gene that results in a stop codon and lack of leptin production was first observed in mice in 1950. In the mouse gene, arginine-105 is encoded by CGA and only requires one nucleotide change to create the stop codon TGA.
As a result,red blood cells spontaneously sickle in the peripheralblood if the amount of sickle hemoglobin is greaterthan 60%.â¢3.Nonsense mutation: altered DNA codes for a stop codonthat causes premature termination of protein synthesis.In p-thalassemia major, a nonsense mutation produces a stop codon that causes premature termination of DNA transcription of the P-globin chain.Consequently, there is a marked decrease in thesynthesis of hemoglobin A (a2(32), resulting in amicrocytic anemia ...