Virtual Design and Construction is the management of integrated multi-disciplinary performance models of design-construction projects, including the product, work processes and organization of the design - construction - operation team in order to support explicit and public business objectives. The theoretical basis of VDC includes: Engineering modeling methods: product, organization, process Analysis methods - Model-based design: including quantities, schedule, cost, 4D interactions and proces
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Protease inhibitors (PIs) are a class of antiviral drugs that are widely used to treat HIV/AIDS and hepatitis caused by hepatitis C virus.iven the specificity of the target of these drugs there is the risk, as in antibiotics, of the development of drug-resistant mutated viruses. To reduce this risk it is common to use several different drugs together that are each aimed at different targets.