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To determine whether breast cancer cells contain hormone receptors, doctors test samples of tumor tissue that have been removed by surgery. If the tumor cells contain estrogen receptors, the cancer is called estrogen receptor positive (ER positive), estrogen sensitive, or estrogen responsive.
Estradiol is a type of estrogen, the major sex hormone in women. It is secreted by the ovarian follicles. As the follicles grow and develop each month, they produce estradiol.This sets the rest of the reproductive cycle in motion.t could also mean that the estradiol is suppressing FSH. Either of these things could mean that you will have more trouble getting pregnant, more trouble ovulating (even with treatment) and reduced success with IVF. In rare cases, high levels of estradiol could indicate an ovarian tumor or hyperthyroidism.