Joe Pesci plays Vinny Gambini, a New York attorney newbie who has to go to Alabama to defend his wrongly accused cousin and friend in a murder trial. Hilarity and profanity ensue. Marisa Tomei plays his argumentative fianc e with a highly-exaggerated New York accent that got her a Best Supporting Actress Oscar.
Parkinson's disease (PD) is a long term disorder of the central nervous system that mainly affects the motor system. The symptoms generally come on slowly over time. Early in the disease, the most obvious are shaking, rigidity, slowness of movement, and difficulty with walking. Thinking and behavioral problems may also occur. Dementia becomes common in the advanced stages of the disease. Depression and anxiety are also common occurring in more than a third of people with PD.
Other symptoms include sensory, sleep and emotional problems. Parkinson's disease is more common in older people, with most cases occurring after the age of 50; when it is seen in young adults, it is called young onset PD (YOPD). The main motor symptoms are collectively called parkinsonism, or a parkinsonian syndrome.