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Promethazine is an antihistamine. It blocks the effects of the naturally occurring chemical histamine in your body. The combination of dextromethorphan and promethazine used to treat cough, itching, runny nose, sneezing, and itchy or watery eyes caused by colds or allergies.
Now in 2015 I was prescribed promethazine DM which had an ... I thought that terpin hydrate with codeine was very helpful vs. guiafenesin with DM. ...Now in 2015 I was prescribed promethazine DM which had an ill effect that didn't help serious coughing and sore....