Hypothetically, if the threshold is normally -60mV, but now we have too much calcium on board, our threshold is now -50mv. That is a difference of 40mV that the cell has to account for in order to depolarize. In skeletal muscle, this can cause weakness, fatigue, etc. Too little calcium will cause the threshold to become more negative (gets closer to the resting membrane potential).
OK, this is probably going to come with you laughing at me... Once in a while I wake up with the back of my head sweating, and it`s more common when I take a nap during the day.
Hormone Imbalance. Night sweats are primarily caused by a hormonal imbalance, according to 34 Menopause Symptoms. Pregnancy night sweats occur when the hypothalamus, the part of the brain responsible for regulating body heat, malfunctions due to a deficiency in the hormone estrogen.