â¢ AUTOIMMUNE DISEASE (noun). The noun AUTOIMMUNE DISEASE has 1 sense: 1. any of a large group of diseases characterized by abnormal functioning of the immune system that causes your immune system to produce antibodies against your own tissues.
The initiation of cell transformation is generally associated with genetic alterations in normal cells that lead to the loss of intercellular-and/or extracellular-matrix- (ECM-) mediated cell adhesion.ancer afflicts an organ or a tissue by inducing abnormal and uncontrolled division of cells that either constitute it or migrate to it. At the cellular level, this is caused by genetic alterations in networks that regulate cell division and cell death.
Genetic Effects. Genetic information for the production and function of a new organ is contained in the chromosomes of germ cells-sperm and ovum. In reality, genetic effects are due to the damages to DNA molecules. Normal human somatic cells contain 46 chromosomes.omatic Effects. Radiation affects rates of cell division. Hastening and slowing down cell division affect embryonic tissues. Damages to cell membranes, mitochondria and cell nuclei result in abnormal cell functions, affecting their division, growth and death.