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Posts. 148. elguapo, It comes with that warning because diphenhydramine, the active ingredient in Unisom, can make urination more difficult. A guy with an enlarged prostate is already going to have difficulty urinating and diphenhydramine would just add to the problem.
Unisom can kill you, in pretty horrid ways. The main ingredient in most over the counter sleep aids is the same thing as Diphenhydramine or Benadryl, which while is an awesome way to get your allergies to stop making you crazy and with the bonus affect of making you sleep it can kill you. response to the overwhelming tide of Google searches of people ending up here searching for information on how to kill themselves with Unisom and other over the counter sleep aids. I giggled over Fantasiaâs suicide attempt with aspirin and Unisom, which was pretty mean in retrospect. Itâs not like sheâs a Sparkle Cow.