Codeine is a narcotic pain-reliever and cough suppressant similar to morphine and hydrocodone. Moreover, a small amount of codeine is converted to morphine in the body. The precise mechanism of action of codeine is not known; however, like morphine, codeine binds to receptors in the brain (opioid receptors) that are important for transmitting the sensation of pain throughout the body and brain. Codeine increases tolerance to pain, decreasing discomfort, but the pain still is apparent to the patient.
âA topical preparation of a skin lightening composition containing MSM in an amount of approximately 1 to 25 weight percent, such as about 15%, or greater than 20% by weight, is applied to a personâs skin in a daily regimen.
MSM can be produced in a lab, where it is sometimes combined with other supplements such as glucosamine or chondroitin. People take MSM by mouth or apply it to the skin, mostly using it to lessen inflammation. They take MSM to try to relieve pain or swelling from: