1. Exogenous Causes. Dry Skin is the most common and obvious cause of itchy soles of the feet. The most likely cause is a lack of moisture in the skin. This affects the elderly more than the younger members of the population and it is found more frequently during the colder winter months.
In molecular genetics, an open reading frame (ORF) is the part of a reading frame that has the potential to code for a protein or peptide. An ORF is a continuous stretch of codons beginning with a start codon (usually AUG) and ending with a stop codon (usually UAA, UAG or UGA). An AUG codon within the ORF (not necessarily the first) may indicate where translation starts.
Non-Down syndrome AMKL is characterized by a limited number of specific genetic abnormalities, including the t(1;22)(p13;q13) translocation fusing RBM15 to MKL1, formerly known as OTT / MAL. 14 In addition, recently Gruber et al. 15 described an inversion of chromosome 16, resulting in CBFA2T3 / GLIS2 gene fusion as a repetitive event in AMKL, with an overall frequency of 27 %.