Metallosis often causes the following symptoms: Cardiomyopathy (heart problems), including heart failure. Depression, anxiety and other mental problems. Visual impairment that may lead to blindness. Cognitive impairment. Nerve problems. Thyroid problems. Auditory impairment that may lead to deafness.
Coordination refers to the coordinate covalent bonds (dipolar bonds) between the ligands and the central atom. Originally, a complex implied a reversible association of molecules, atoms, or ions through such weak chemical bonds. As applied to coordination chemistry, this meaning has evolved.
2 The systematic review authors combined the common elements from many definitions to develop one working definition for use in identifying reviews of interventions in the vicinity of care coordination and, as a result, developed a purposely broad definition: Care coordination is the deliberate organization of patient care activities between two or more participants (including the patient) involved in a patient's care to facilitate the appropriate delivery of health care services.