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Posts. 148. elguapo, It comes with that warning because diphenhydramine, the active ingredient in Unisom, can make urination more difficult. A guy with an enlarged prostate is already going to have difficulty urinating and diphenhydramine would just add to the problem.
Anonymous 7 Feb 2014. Hello Barnany Bear. My suggestion would be Unisom. However, my opinion would be to a prescription, (if possible) as most all the OTC sleeping aids are ineffective if the insomnia is considered to be severe . Regrds pledge.