Metallosis often causes the following symptoms: Cardiomyopathy (heart problems), including heart failure. Depression, anxiety and other mental problems. Visual impairment that may lead to blindness. Cognitive impairment. Nerve problems. Thyroid problems. Auditory impairment that may lead to deafness.
Coordination refers to the coordinate covalent bonds (dipolar bonds) between the ligands and the central atom. Originally, a complex implied a reversible association of molecules, atoms, or ions through such weak chemical bonds. As applied to coordination chemistry, this meaning has evolved.
Clinical coordination involves determining where to send the patient next (e.g., sequencing among specialists), what information about the patient is necessary to transfer among health care entities, and how accountability and responsibility is managed among all health care professionals (doctors, nurses, social workers, care managers, supporting staff, etc.).