When an arrhythmia causes the heart to beat too fast, the heart doesn't pump effectively. Specifically, there may not be enough time between heartbeats for the heart to fill with blood, causing blood to back up into the lungs.
The new non-steroidal and steroidal aromatase inhibitors are at least as effective as megestrol acetate (MA) as second-line hormonal agents in postmenopausal women with breast cancer.However, they are superior to MA in terms of tolerability and adverse effects.he Type I inhibitors have a steroidal structure similar to androgens and inactivate the enzyme irreversibly by blocking the substrate-binding site, and are therefore known as aromatase inactivators. Examples of such drugs include formestane and exemestane (Aromasin).
Exercise to Prevent Aromatase Inhibitor Side Effects in Breast Cancer Patients (BCS2) This study has been terminated. Hormone receptor-positive tumors are the most common breast cancers in postmenopausal women, and drug therapies, which block the production or effects of estrogen, are the mainstay of treatment in these patients.