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To determine whether breast cancer cells contain hormone receptors, doctors test samples of tumor tissue that have been removed by surgery. If the tumor cells contain estrogen receptors, the cancer is called estrogen receptor positive (ER positive), estrogen sensitive, or estrogen responsive.
Synthetic estrogens are used as part of some oral contraceptives, in estrogen replacement therapy for postmenopausal women, and in hormone replacement therapy for trans women.strogen may also refer to any substance, natural or synthetic that mimics the effects of the natural hormone. The steroid 17Î²-estradiol is the most potent and prevalent endogenous estrogen, but several metabolites of estradiol also have estrogenic hormonal activity.