Splenic-flexure syndrome is a chronic disorder that may be caused by gas trapped at bends (flexures) in the colon. Crohn's disease, colon cancer, or any disease that causes intestinal obstruction, may also cause abdominal bloating. Internal hernias or adhesions (scar tissue) from surgery may cause bloating or pain.
For many years it was thought that the maximum number of folds that could be achieved was just seven! This was the case until when in 2002 American teenager Britney Gallivan demonstrated that a sheet of paper can be folded 12 times, provided that it is long enough and thin enough.
Folded business cards (also called double or brochure business cards) are usually about 3.5 inches by 4 inches folded to 3.5 by 2. They can be designed as top fold cards or side fold. When designing business cards with a bleed, use a document size of 3.75 x 2.25 inches (.25 inch bleed allowance).