Tensor tympani- The tensor tympani is the larger of the two muscles of the auditory canal, the other being stapedius. The muscle functions to dampen down sounds such as chewing. It arises from the cartilaginous portion of the eustachian tube as well as the adjacent section of the greater wing of the sphenoid bone.
A nonsense mutation in the leptin gene that results in a stop codon and lack of leptin production was first observed in mice in 1950. In the mouse gene, arginine-105 is encoded by CGA and only requires one nucleotide change to create the stop codon TGA.
Leptin is a 167 amino acid protein encoded by the ob gene. It has been found that leptin is produced for the most part in white adipose tissue, with very small amounts being found in brown adipose tissue.Leptin is a four-helix bundle with one very short strand segment and two relatively long interconnected loops.egulator of metabolism. Small amounts of leptin are also secreted by cells in the epithelium, stomach and placenta. Leptin is a protein hormone with important effects in regulating body weight, metabolism and reproductive function.