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To determine whether breast cancer cells contain hormone receptors, doctors test samples of tumor tissue that have been removed by surgery. If the tumor cells contain estrogen receptors, the cancer is called estrogen receptor positive (ER positive), estrogen sensitive, or estrogen responsive.
Hormone status of breast cancers includes: 1  Estrogen receptor (ER) positive. 2  This type of breast cancer is sensitive to estrogen and may respond to hormone therapy. 3  Progesterone receptor (PR) positive. 4  This type of breast cancer is sensitive to progesterone and may respond to hormone therapy.