In 1890, private detective Sherlock Holmes (Robert Downey Jr.) and his partner Dr. John Watson (Jude Law) race to prevent the ritual murder of a woman by Lord Henry Blackwood (Mark Strong), who has killed five other young women similarly.
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The formation of the peptide bond consumes energy, which, in living systems, is derived from ATP. Polypeptides and proteins are chains of amino acids held together by peptide bonds. Living organisms employ enzymes to produce polypeptides, and ribosomes to produce proteins. Peptides are synthesized by specific enzymes. For example, the tripeptide glutathione is synthesized in two steps from free amino acids, by two enzymes: gamma-glutamylcysteine synthetase and glutathione synthetase. The condensation of two amino acids to form a peptide bond (red) with expulsion of water (blue)