For a single return trip from Paris to Brussels, a point to point ticket is the best value for money and the cheapest train ticket. Best prices are available when buying the train ticket well in advance. For extensive train travel, a rail pass for France and Belgium is a better choice.
creÂ·tinÂ·ism. n. A congenital condition caused by a deficiency of thyroid hormone during prenatal development and characterized in childhood by dwarfed stature, mental retardation, dystrophy of the bones, and a low basal metabolism. Also called congenital myxedema. (ËkrÉtÉªËnÉªzÉm).
The roles of the pituitary gland and hypothalamus, which control thyroid hormone levels via secretion of TSH and TRH, respectively, have been discussed elsewhere. A fourth class of hypothyroidism is congenital...implying a defect at birth that affects thyroid hormone synthesis, transport to tissues or iodine metabolism.