More directly relevant is the level of kidney function. In patients with poor kidney function or those on dialysis, the drug can accumulate to levels above the theraputic range. There are several reports of abnormal movements (myoclonus) when this occurs. Common practice is to start at a lower dose in these patients.
Bleach (Nirvana album) Bleach is the debut studio album by American rock band Nirvana, released on June 15, 1989 by Sub Pop. The main recording sessions took place at Reciprocal Recording in Seattle, Washington between December 1988 and January 1989.
Bleach is a chemical that whitens clothing. The bleaching process has been known for millennia, but the chemicals currently used for bleaching resulted from the work of several 18th century scientists.