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Uremia or uraemia (see spelling differences) can be translated as  urea in the blood.Urea is one of the primary components of urine. It can be defined as an excess of amino acid and protein metabolism end products, such as urea and creatinine, in the blood that would be normally excreted in the urine.The Uremic Syndrome can be defined as the terminal clinical manifestation of kidney failure (also called renal failure).It is the signs, symptoms and results from laboratory tests which result from inadequate excretory, regulatory and endocrine function of the kidneys.he Uremic Syndrome can be defined as the terminal clinical manifestation of kidney failure (also called renal failure). It is the signs, symptoms and results from laboratory tests which result from inadequate excretory, regulatory and endocrine function of the kidneys.
Urea is a less toxic compound than ammonia; two nitrogen atoms are eliminated through it and less water is needed for its excretion. Urea is a protein metabolism product at vertebrates and part of the invertebrates. These organisms are called  ureotelic .ll the metabolic wastes are excreted in a form of water solutes through the excretory organs (nephridia, Malpighian tubules, kidneys), with the exception of CO 2, which is excreted together with the water vapor throughout the lungs.