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1 Epstein-Barr virus (EBV) is a contagious infection that causes infectious mononucleosis. 2  The illness is spread by casual contact, usually via saliva. 3  Mono has an incubation period of 4 to 6 weeks. The illness is spread by casual contact, usually via saliva. 2  Mono has an incubation period of 4 to 6 weeks. 3  The vast majority of adults have antibodies against EBV, meaning they have been infected with the virus and are immune to mono.
As you probably know, mono, or infectious mononucleosis, is a common viral infection which typically occurs in teenagers and young adults. Symptoms include sore throat, swollen glands in the neck, and fatigue. Most of the time, the condition is not serious, however symptoms can linger for a long time and can result in trouble keeping up with work or school obligations.