Project managed by RPC Oevel who provide the single point of contact for the customer, RPC Oevel are supplying 300 and 675ml bottles from their standard range, while RPC Kutenholz are producing two custom-moulded designs.
Production of Thrombopoietin. The liver is the major producer of Thrombopoietin in the human body. It has special cells that handle the production of several hormones including Thrombopoietin. Both the parenchymal cells and sinusoidal cells of the liver play a major role in the production of this hormone.
Description. Prothrombin (factor II) is the precursor of thrombin in the coagulation pathway; it is synthesized in the liver, much as other vitamin Kâdependent proteins are, and has a molecular weight of 72 kd. The plasma half-life of prothrombin is approximately 60 hours. The prothrombin gene is found at 11p11-q12) on chromosome 11. Mutation at position 20210 of the gene results in thrombophilia. The prevalence of factor II G20210A in Caucasian populations is estimated to be in the range of 1-6%.