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1 Epstein-Barr virus (EBV) is a contagious infection that causes infectious mononucleosis. 2  The illness is spread by casual contact, usually via saliva. 3  Mono has an incubation period of 4 to 6 weeks. The illness is spread by casual contact, usually via saliva. 2  Mono has an incubation period of 4 to 6 weeks. 3  The vast majority of adults have antibodies against EBV, meaning they have been infected with the virus and are immune to mono.
Infectious mononucleosis, mono, kissing disease, and glandular fever are all terms popularly used for the very common infection caused by the Epstein-Barr virus (EBV). The characteristic symptoms of infection with EBV include fever, fatigue, malaise, and sore throat.The designation  mononucleosis  refers to an increase in a particular type of mononuclear white blood cells (lymphocytes) in the bloodstream relative to the other white blood cells as a result of the EBV infection. The infection can be spread by saliva, and the incubation period for mono is four to eight weeks. 2  Most adults have laboratory evidence (antibodies against the EBV) indicative of a previous infection with EBV and are immune to further infection. 3  The symptoms of mono include: 4  fever, 5  fatigue, 6  sore throat, and.