This chapter contains a review of the technical procedures for handling endometrial tissues and a discussion of the morphologic aspects of the endometrium, focusing on the interpretation and understanding of the physiomorphology of the endometrial cycle.
A one-month supply of 40-mg febuxostat costs $160. This price far exceeds the cost of allopurinol, which is $14 (brand: $31) for a one-month supply.Febuxostat is available in 40-mg and 80-mg tablets. The initial dosage is 40 mg once per day, increasing to 80 mg once per day if serum uric acid levels remain at 6 mg per dL or higher after two weeks of therapy.Dosage adjustments are unnecessary for mild to moderate renal or hepatic impairment.IMPLICITY. Febuxostat is available in 40-mg and 80-mg tablets. The initial dosage is 40 mg once per day, increasing to 80 mg once per day if serum uric acid levels remain at 6 mg per dL or higher after two weeks of therapy. Dosage adjustments are unnecessary for mild to moderate renal or hepatic impairment.
Cost. In general, long-term uric-acid lowering therapy, such as allopurinol, probenecid, or febuxostat, may not be warranted in all patients but is most appropriate in patients with recurrent acute attacks, tophi, radiographic evidence of joint damage, and urate nephrolithiasis.llopurinol and probenecid are currently available as generics, with prices of $0.24 per unit for allopurinol 100-mg tablets, $0.64 per unit for allopurinol 300-mg tablets, and $0.98 per unit for probenecid 500-mg tablets.