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Difference Between Physiological & Pathological Jaundice. Physiological and pathological jaundice both result in a yellow tint to the skin, whites of the eyes and mucous membranes but are caused by different conditions. Physiological Jaundice. When jaundice occurs in a healthy baby, it is considered physiological jaundice.
Jaundice refers to a yellowish color of the skin or whites of the eyes. When red blood cells die, they release hemoglobin into the bloodstream. The hemoglobin is broken down into a compound called bilirubin, which gives the skin and eyes a yellowish color. Bilirubin also causes urine to be dark yellow or brown. Severe Reaction to a Blood Transfusion. You may develop hemolytic anemia due to a blood transfusion. This can happen if the transfused blood is a different blood type than your blood. Signs and symptoms of a severe reaction to a transfusion include fever, chills, low blood pressure, and shock.