prometaphase. Prometaphase is the second phase of mitosis, the process that separates the duplicated genetic material carried in the nucleus of a parent cell into two identical daughter cells. During prometaphase, the physical barrier that encloses the nucleus, called the nuclear envelope, breaks down. The breakdown of the nuclear envelope frees the sister chromatids from the nucleus, which is necessary for separating the nuclear material into two cells.
The Sistine Chapel ceiling, painted by Michelangelo between 1508 and 1512, is a cornerstone work of High Renaissance art. The ceiling is that of the Sistine Chapel, the large papal chapel built within the Vatican between 1477 and 1480 by Pope Sixtus IV, for whom the chapel is named. It was painted at the commission of Pope Julius II. The chapel is the location for papal conclaves and many other important services.
Michelangelo, Creation of Adam, from the ceiling of the Sistine Chapel in the Vatican, Rome, 1508-1512, fresco. The most famous section of the Sistine Chapel ceiling is Michelangeloâs Creation of Adam. This scene is located next to the Creation of Eve, which is the panel at the center of the room, and the Congregation of the Waters, which is closer to the altar. The Creation of Adam differs from typical Creation scenes painted up until that time.