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Ulcerative colitis causes swelling in the large intestine and can lead to cramping, diarrhea, and more. Celiac disease Celiac disease, which is an intestinal reaction to gluten, can cause gas, diarrhea, bloating, and weight loss.
In ulcerative colitis, constipation may be a symptom of inflammation of the rectum (known as proctitis). The loss of fluid and nutrients from diarrhea and chronic inflammation of the bowel can also cause fever, fatigue, weight loss, and malnutrition. Pain is usually from the abdominal cramping, which is caused by irritation of the nerves and muscles that control intestinal contractions.