A temporary file created with is deleted automatically when the program exits or the file is closed. To generate a temporary file name that will survive past the lifespan of the creating program, (POSIX) or GetTempFileName(...) (Windows) can be used.
Granulation tissue is new connective tissue and tiny blood vessels that form on the surfaces of a wound during the healing process. Granulation tissue typically grows from the base of a wound and is able to fill wounds of almost any size.
Here is some helpful information about what you can do in case granulation tissue arises: Reduced friction. As the granulation tissue is caused by the body trying to heal itself, friction around the tube area is likely to encourage the growth of granulation tissue, so try to use soft textiles and cover the tube outlet.