In summary, we have shown the inhibitory effects of Bcl-2 family on the ceramide-mediated apoptotic pathway in glioma cells. Bcl-2 is considered to act not only downstream of ceramide to inhibit cytochrome c release followed by caspase activation, but also upstream of or at SMase to prevent ceramide generation.igure 3 Effects of Bcl-2 or Bax overexpression on ceramide formation and neutral sphingomyelinase activation in etoposide-treated C6 cells. C6/Neo (), C6/Bcl-2 (), and C6/Bax () cells were treated with 40 M etoposide for indicated periods.
Hawaii, which has the highest-paid waiters and waitresses in the country (mean wage: $13.91/hour) has a minimum wage of $7.00 for tipped employees.
As of today, Feb 21, 2011, Wait staff must receive 1/2 minimum wage ($7.25 = $3.63 hr). However the server must make the minimum $7.25 per/hr once tips and wages are combined. Any shortage of the $7.25/hr must be made up by the employer.he employer is given what they call a tip credit. In order to pay a waitress the 2.63 per hour, the wai â¦ tress must make up the difference between 2.63 and the state minimum of 8.00. Which would be 5.37 per hour in tips.