Dysfunction in the sacroiliac joint, also called the SI joint, can sometimes cause lower back and/or leg pain. Leg pain from sacroiliac joint dysfunction can be particularly difficult to differentiate from radiating leg pain caused by a lumbar disc herniation (sciatica) as they can feel quite similar.
Systemic lupus erythematosus (SLE), also known simply as lupus, is an autoimmune disease in which the bodyâs immune system mistakenly attacks healthy tissue in many parts of the body. Symptoms vary between people and may be mild to severe.
Systemic lupus erythematosus (SLE, or lupus) is a long-term autoimmune disease that triggers inflammatory damage throughout the body, including the skin, joints, lungs, cardiovascular structures, nervous system and kidneys.There is no cure, and the underlying cause is not fully understood.n international team of researchers led by Chaim O. Jacob, associate professor of medicine and microbiology & immunology at the Keck School of Medicine of USC, has identified a gene mutation involved in causing lupus, a chronic inflammatory disease that affects the skin, joints and organs.