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Ulcerative colitis causes swelling in the large intestine and can lead to cramping, diarrhea, and more. Celiac disease Celiac disease, which is an intestinal reaction to gluten, can cause gas, diarrhea, bloating, and weight loss.
Photo: Getty Images. Living with an inflammatory bowel disease (IBD), such as Crohn's disease or ulcerative colitis, is a challenge. People with these serious conditions can lose weight during a flare-up and gain it all backâand then someâif they need to take corticosteroids to get symptoms under control.