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Answer Wiki. Summary: peak running performance after donating blood may be impacted for up to 1-2 weeks after donating 1 pint of blood, but is most noticeably impacted within the first 1-2 days after donating when attempting to perform at peak levels during endurance activities.
If you have any concerns about donating blood at this time, here are some important tips and information to help ease your mind. If You Have the Flu. If you are not feeling well on the day of donation, you will be deferred from giving blood. If you have the flu, you should wait until you no longer have flu symptoms, have recovered completely and feel well before you attempt to donate. Blood donors must feel healthy and well on the day of donation.