Definition of inference for English Language Learners. : 1  the act or process of reaching a conclusion about something from known facts or evidence. : 2  a conclusion or opinion that is formed because of known facts or evidence.
Causes of Clogged Arteries. There are many substances and properties that can circulate with the blood, including cholesterol, calcium, fat, fibrin and cellular waste. When these substances accumulate on the inner walls of the arteries, they turn into plaque buildup.
Coronary heart disease (CHD), also called coronary artery disease, occurs when plaque builds up in the coronary arteries. These arteries supply oxygen-rich blood to your heart. Plaque narrows the coronary arteries and reduces blood flow to your heart muscle. Plaque buildup also makes it more likely that blood clots will form in your arteries. Blood clots can partially or completely block blood flow. If blood flow to your heart muscle is reduced or blocked, you may have angina (chest pain or discomfort) or a heart attack.