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Plymouth was colder, whereas Jamestown was warmer and more humid, and therefore more prone to harbor diseases. I'm sure that there were a lot more differences, but those are the big ones that leapt into my mind.
Plymouth (/ËplÉªmÉÎ¸/) is a city on the south coast of Devon, England, about 37 miles (60 km) south-west of Exeter and 190 miles (310 km) west-south-west of London, between the mouths of the rivers Plym to the east and Tamar to the west where they join Plymouth Sound to form the boundary with Cornwall.n 1914 three neighbouring independent towns, viz., the county borough of Plymouth, the county borough of Devonport, and the urban district of East Stonehouse were merged to form a single County Borough. The combined town took the name of Plymouth which, in 1928, achieved city status.