Mutation is a change in DNA, the hereditary material of life. An organism's DNA affects how it looks, how it behaves, and its physiology  all aspects of its life. So a change in an organism's DNA can cause changes in all aspects of its life.
continuously variable transmission (CVT)=An automatic transmission that can change seamlessly through an infinite number of effective gear ratios between maximum and minimum values. Automatic transmission= Automatically change gear ratios as the vehicle moves, freeing the driver from having to shift gears manually.
Regadenoson (CVT-3146, Lexiscan) is an A2A adenosine receptor agonist that is a coronary vasodilator that is commonly used in pharmacologic stress testing. It produces hyperemia quickly and maintains it for a duration that is useful for radionuclide myocardial perfusion imaging.