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This type of pain is usually localized, affecting just a few muscles or a small part of your body. Systemic muscle pain â pain throughout your whole body â is more often the result of an infection, an illness or a side effect of a medication. Common causes of muscle pain include: Chronic exertional compartment syndrome. Chronic fatigue syndrome.
Muscle pain also can be a sign of conditions affecting your whole body, like some infections and disorders that affect connective tissues throughout the body. Most common cause of muscle aches & pains: Injury or trauma including sprains and strains. Overuse: using a muscle too much, too soon, too often.