Providers and consumers should realize that isotretinoin is a potent drug with the potential to cause birth defects and reserve its use for severe recalcitrant nodular acne. Isotretinoin is not for use in mild forms of acne and should not be shared among family members.
Most orbital motorways (or beltways) are purpose-built major highways around a town or city, typically without either signals or road or railroad crossings. In the United States, beltways are commonly parts of the Interstate Highway System. Similar roads in the United Kingdom are often called orbital motorways.
Highway 15 (Jordan) Highway 15 in Jordan is also known as the Desert Highway runs in Jordan south to north. It starts in Aqaba going north east towards Ma'an, passing through the desert to the east of the major settlements in the southern region of Jordan. It then merges into the regional Highway 35 going to Amman.