In summary, we have shown the inhibitory effects of Bcl-2 family on the ceramide-mediated apoptotic pathway in glioma cells. Bcl-2 is considered to act not only downstream of ceramide to inhibit cytochrome c release followed by caspase activation, but also upstream of or at SMase to prevent ceramide generation.igure 3 Effects of Bcl-2 or Bax overexpression on ceramide formation and neutral sphingomyelinase activation in etoposide-treated C6 cells. C6/Neo (), C6/Bcl-2 (), and C6/Bax () cells were treated with 40 M etoposide for indicated periods.
Hawaii, which has the highest-paid waiters and waitresses in the country (mean wage: $13.91/hour) has a minimum wage of $7.00 for tipped employees.
Most waitresses are paid by the hour and earn tips on top of their hourly wages. Average tips for a waitress are 15 to 20 percent of the total bill, according to iTipping.com. Therefore, a waitress that rings up $400 during a four-hour shift should make $60 to $80 in tips.Average hourly rates for waitresses were $9.95 as of May 2012, according to the U.S Bureau of Labor Statistics -- or $20,710 per year. This equates to $1,725.83 per month. The top 10 percent made over $2,459.16 monthly.herefore, a waitress that rings up $400 during a four-hour shift should make $60 to $80 in tips. Average hourly rates for waitresses were $9.95 as of May 2012, according to the U.S Bureau of Labor Statistics -- or $20,710 per year.