Definition of GRAVAMEN: The burden or gist of a charge; the grievance or injury specially complained of.In English ecclesiastical law. A grievance complained of by the clergy befo The Law Dictionary Featuring Black's Law Dictionary Free Online Legal Dictionary 2nd Ed.
Phosphate and sugar make up the sides of a DNA ladder.
The rungs of the ladder are pairs of units between A and T or between C and G. These pairs are called base pairs and they connect the two sugar-phosphate backbones through interactions called hydrogen bonds. In cells, the DNA helix is often overwound, causing a phenomenon known as supercoiling.