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Bile acid sequestrants are polymeric compounds that serve as ion-exchange resins. Bile acid sequestrants exchange anions such as chloride ions for bile acids.By doing so, they bind bile acids and sequester them from the enterohepatic circulation. The liver then produces more bile acids to replace those that have been lost.ile acid sequestrants are large polymeric structures, and they are not significantly absorbed from the gut into the bloodstream. Thus, bile acid sequestrants, along with any bile acids bound to the drug, are excreted via the feces after passage through the gastrointestinal tract.
When exercising, losing weight, and dietary changes do not reduce cholesterol to the desired level, medication may be necessary. Major types of medicine for cholesterol include statins, fibrates, cholesterol absorption inhibitors, and nicotinic acid, among others. Statins are prescribed the most frequently, and are often combined with bile acid sequestrants to lower bad cholesterol levels by over 40 percent.