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This type of pain is usually localized, affecting just a few muscles or a small part of your body. Systemic muscle pain â pain throughout your whole body â is more often the result of an infection, an illness or a side effect of a medication. Common causes of muscle pain include: Chronic exertional compartment syndrome. Chronic fatigue syndrome.
Emotional and physical stress can contribute muscles to tense and spasm causing soreness and pain. Muscle tightness may also happen due to the stiffness of muscles which is due to the inflammation of the muscles or joints. Obesity, diabetes, infections, hormonal balances can also cause inflammation of muscles leading to stiffness.