Evidence-based practice of psychology requires practitioners to follow psychological approaches and techniques that are based on the best available research evidence (Sackett, Straus, Richardson, Rosenberg, & Haynes, 2000).nfortunately, the term evidence-based practice is not always used in such a rigorous fashion, and many psychologists claim to follow evidence-based approaches even when the methods they use do not meet established criteria for efficacy (Berke, Rozell, Hogan, Norcross, and Karpiak, 2011).
Neuromuscular disease is a very broad term that encompasses many diseases and ailments that impair the functioning of the muscles, either directly, being pathologies of the muscle, or indirectly, being pathologies of nerves or neuromuscular junctions.yasthenia gravis and LambertâEaton syndrome are examples of neuromuscular junction disorders. Muscular dystrophies and inflammatory myopathies such as polymyositis are examples of primary muscular (myopathic) disorders.
A neuromuscular junction (sometimes called a myoneural junction) is a junction between nerve and muscle; it is a chemical synapse formed by the contact between the presynaptic terminal of a motor neuron and the postsynaptic membrane of a muscle fiber.AChRs are ionotropic receptors, meaning they serve as ligand-gated ion channels. The binding of ACh to the receptor can depolarize the muscle fiber, causing a cascade that eventually results in muscle contraction. Neuromuscular junction diseases can be of genetic and autoimmune origin.