prometaphase. Prometaphase is the second phase of mitosis, the process that separates the duplicated genetic material carried in the nucleus of a parent cell into two identical daughter cells. During prometaphase, the physical barrier that encloses the nucleus, called the nuclear envelope, breaks down. The breakdown of the nuclear envelope frees the sister chromatids from the nucleus, which is necessary for separating the nuclear material into two cells.
The Sistine Chapel ceiling, painted by Michelangelo between 1508 and 1512, is a cornerstone work of High Renaissance art. The ceiling is that of the Sistine Chapel, the large papal chapel built within the Vatican between 1477 and 1480 by Pope Sixtus IV, for whom the chapel is named. It was painted at the commission of Pope Julius II. The chapel is the location for papal conclaves and many other important services.
Michelangelo, master of sculpting and painting, knew about the Jesse Tree in art, knew the Bible well and studied it thoroughly in order to be able to put such a subtle, arcane reference to Jesusâ genealogy in the Pieta and to place Biblical references in all of his paintings in the Sistine Chapel. When he was 33 in 1508, he started work on the ceiling of the Sistine Chapel in Rome. Cleverly hid self-portrait of Michelangelo on the flayed skin of St. Bartholomew in the Last Judgment section (over altar) in the Sistine Chapel.