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1 Epstein-Barr virus (EBV) is a contagious infection that causes infectious mononucleosis. 2  The illness is spread by casual contact, usually via saliva. 3  Mono has an incubation period of 4 to 6 weeks. The illness is spread by casual contact, usually via saliva. 2  Mono has an incubation period of 4 to 6 weeks. 3  The vast majority of adults have antibodies against EBV, meaning they have been infected with the virus and are immune to mono.
Signs and symptoms of mono. A child or teen can have infectious mononucleosis from EBV for some time before showing any symptoms. This is known as the incubation time of a virus. The incubation time for mono can be up to 30 to 50 days in teens, but it is shorter for children. Children. In children, mono typically shows very few or no symptoms.