In the 1946 elections to the Indian constituent assembly, the Congress lost the Muslim vote to the Muslim League; it reluctantly accepted the partition of the Indian subcontinent and the formation of the state of Pakistan. After partition the Congress, as the largest party, governed India under Nehru's leadership.
ACTH is a hormone produced in the anterior pituitary gland that stimulates the adrenal glands to release cortisol, dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (DHEA-S), and aldosterone.
It is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress (along with its precursor corticotropin-releasing hormone from the hypothalamus). Its principal effects are increased production and release of cortisol by the cortex of the adrenal gland.37â241. In order to regulate the secretion of ACTH, many substances secreted within this axis exhibit slow/intermediate and fast feedback-loop activity.