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Ulcerative colitis causes swelling in the large intestine and can lead to cramping, diarrhea, and more. Celiac disease Celiac disease, which is an intestinal reaction to gluten, can cause gas, diarrhea, bloating, and weight loss.
Ulcerative colitis symptoms can vary, depending on the severity of inflammation and where it occurs. Therefore, doctors often classify ulcerative colitis according to its location. You may have the following signs and symptoms, depending on which part of the colon is inflamed: 1  Diarrhea, often with blood or pus. 2  Abdominal pain and cramping. 3  Rectal pain. 4  Rectal bleeding â passing small amount of blood with stool. 5  Urgency to defecate. 6  Inability to defecate despite urgency. 7  Weight loss. 8  Fatigue.