In addition, thiazolidinediones have several other potential side effects, which make them less appealing as initial or second step therapy. (See 'Cardiovascular effects' below and 'Safety' below.). The pharmacology and use of thiazolidinediones will be reviewed here.
Alcohol impairs brain areas such as the cerebellumâthe control site for your balance and coordinationâand your cerebral cortex, which is responsible for thinking, memory, and learning, says Kimberly S. Walitzer, Ph.D., deputy director of the University at Buffaloâs Research Institute on Addictions.
While being metabolized, alcohol is distributed throughout the body, affecting the brain and other tissues. Within minutes of being ingested, alcohol reaches the brain and initially gives the temporary impression of being a stimulant. Alcohol goes on to act as a depressant and a sedative, producing a sense of calm.