Cancer staging can be divided into a clinical stage and a pathologic stage. In the TNM (Tumor, Node, Metastasis) system, clinical stage and pathologic stage are denoted by a small c or p before the stage (e.g., cT3N1M0 or pT2N0). This staging system is used for most forms of cancer, except brain tumors and hematological malignancies.
The English language is the sole official language of England and Gibraltar and one of the official languages of the Republic of Ireland, Northern Ireland, Scotland, Wales, Malta, the Isle of Man, Jersey, Guernsey and the European Union.n the Kingdom of the Netherlands, English has an official status as a regional language on the isles of Saba and Sint Eustatius. In other parts of Europe, English is spoken mainly by those who have learnt it as a second language, but also, to a lesser extent, natively by expatriates from the English-speaking world.
Early Modern English began in the late 15th century with the introduction of the printing press to London and the King James Bible as well as the Great Vowel Shift. Through the worldwide influence of the British Empire, modern English spread around the world from the 17th to mid-20th centuries.s of 2010 359 million people spoke English as their first language. English is probably the third largest language by number of native speakers, after Mandarin and Spanish. However, when combining native and non-native speakers it is probably the most commonly spoken language in the world.