A. Multiple myeloma is a malignant, clonal disorder of plasma cells that originates in the bone marrow. Itâs a relatively common disorder, accounting for 1% of all malignancies and 10% of all hematologic malignancies in adults.
torsion, n 1. , motion or state of torque in which one end of an anatomical component is twisted about its longitudinal axis as the opposite end is either immobile or moves in the opposite direction.
Tibial torsion is inward twisting of the tibia (shinbone) and is the most common cause of intoeing. It is usually seen at age 2 years. Males and females are affected equally, and about two thirds of patients are affected bilaterally. Normally, lateral rotation of the tibia increases from approximately 5Âº at birth to approximately 15Âº at maturity.