Mutation is a change in DNA, the hereditary material of life. An organism's DNA affects how it looks, how it behaves, and its physiology  all aspects of its life. So a change in an organism's DNA can cause changes in all aspects of its life.
continuously variable transmission (CVT)=An automatic transmission that can change seamlessly through an infinite number of effective gear ratios between maximum and minimum values. Automatic transmission= Automatically change gear ratios as the vehicle moves, freeing the driver from having to shift gears manually.
Introduction. To the Editor: Sir, the study by Canhao and colleagues made the important point that the most frequent cause of death in patients with cerebral venous thrombosis (CVT) is transtentorial herniation and that these patients may potentially have benefited from decompressive hemicraniectomy.