If one is talking about interstate business, a company that is in one state provides its products and services to a customer in another state or several states. Intrastate. Intrastate refers to anything that pertains to a single state and does not require crossing over the boundaries of a single state.
H. pylori was first discovered in the stomachs of patients with gastritis and ulcers in 1982 by Drs. Barry Marshall and Robin Warren of Perth, Australia. At the time, the conventional thinking was that no bacterium could live in the acid environment of the human stomach.
H. pylori bacteria can cause ulcers by growing in the lining of the stomach, producing inflammation and causing the stomach and intestinal lining to be more easily damaged by stomach acid. But most people infected with H. pylori do not develop ulcers.