Marjoram is a perennial herb in the mint family that grows wild in the Mediterranean region. It is used primarily as seasoning in cooked dishes but is also found in beauty and health care products. Often mistaken for oregano, marjoram is frequently called by many different names, including sweet marjoram, knotted marjoram, joy of the mountains, and wintersweet.
The structure of paclitaxel, a widely used mitotic inhibitor. A mitotic inhibitor is a drug that inhibits mitosis, or cell division. These drugs disrupt microtubules, which are structures that pull the cell apart when it divides. Mitotic inhibitors are used in cancer treatment, because cancer cells are able to grow and eventually spread through the body (metastasize) through continuous mitotic division.
A cyclin-dependent kinase inhibitor (CKI) is a protein that interacts with a cyclin-CDK complex to block kinase activity, usually during G1 or in response to signals from the environment or from damaged DNA. In animal cells, there are two major CKI families: the INK4 family and the CIP/KIP family.he structure of human Cdk2 revealed that CDKs have a modified ATP-binding site that can be regulated by cyclin binding. Phosphorylation by CDK-activating kinase (CAK) at Thr 161 on the T-loop increases the complex activity.