In addition, thiazolidinediones have several other potential side effects, which make them less appealing as initial or second step therapy. (See 'Cardiovascular effects' below and 'Safety' below.). The pharmacology and use of thiazolidinediones will be reviewed here.
Alcohol impairs brain areas such as the cerebellumâthe control site for your balance and coordinationâand your cerebral cortex, which is responsible for thinking, memory, and learning, says Kimberly S. Walitzer, Ph.D., deputy director of the University at Buffaloâs Research Institute on Addictions.
Alcohol does this by interacting with the receptors on the receiving cells in these pathways. Alcohol affects various centers in the brain, both higher and lower order. The centers are not equally affected by the same BAC -- the higher-order centers are more sensitive than the lower-order centers. As the BAC increases, more and more centers of the brain are affected. The order in which alcohol affects the various brain centers is as follows: Cerebral cortex.