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Myelodysplastic syndromes (MDS). 1  Is a diagnosis of cancer. 2  Is a group of diseases of the blood and bone marrow, with varying degrees of severity, treatment needs and life expectancy. 3  May be primary (de novo) or treatment-related. 4  Primary MDS has no obvious cause.
Myelodysplastic syndromes (MDS) are characterized by bone marrow failure due to disturbed bone marrow maturation. MDS is associated with increased risk of transformation to acute myeloid leukemia (AML... Autoimmune Diseases and Myelodysplastic Syndromes. Immune dysregulation and altered T-cell hemostasis play important roles in the pathogenesis of myelodysplastic syndromes (MDS).