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Myelodysplastic syndromes (MDS). 1  Is a diagnosis of cancer. 2  Is a group of diseases of the blood and bone marrow, with varying degrees of severity, treatment needs and life expectancy. 3  May be primary (de novo) or treatment-related. 4  Primary MDS has no obvious cause.
Disease Overview. Note: Juvenile myelomonocytic leukemia (JMML) was classified as a myelodysplastic syndrome (MDS) under the French-American-British scheme.[1] The World Health Organization classification removed JMML from MDS, placing it in the new category Myelodysplastic/ Myeloproliferative Neoplasms (MDS/MPN).[1-3]