Providers and consumers should realize that isotretinoin is a potent drug with the potential to cause birth defects and reserve its use for severe recalcitrant nodular acne. Isotretinoin is not for use in mild forms of acne and should not be shared among family members.
Most orbital motorways (or beltways) are purpose-built major highways around a town or city, typically without either signals or road or railroad crossings. In the United States, beltways are commonly parts of the Interstate Highway System. Similar roads in the United Kingdom are often called orbital motorways.
This artery of commerce and travel was known as El Camino Real, which meant Royal Road or Kingâs Highway. Of the great highways leading north, this was the oldest, having been extended by segments throughout the 16th century. For a time, it also enjoyed the distinction of being the longest road in North America.