At the synapse, or the motor end plate, acetylcholine opens sodium channels causing sodium influx into the muscle fiber causing depolarization. This depoâ¦larization causes calcium released from the sarcoplasmic reticulum that initiates muscle contraction by activating sarcomeres.
On average, girls begin puberty around ages 10â11; boys around ages 11â12. Girls usually complete puberty around ages 15â17, while boys usually complete puberty around ages 16â17. The major landmark of puberty for females is menarche, the onset of menstruation, which occurs on average between ages 12â13; for males, it is the first ejaculation, which occurs on average at age 13.
Puberty starts on average in girls between ages 8 and13 and in boys between ages 9 and 14. Doctors diagnose early puberty when this normal process starts early and continues to progress through growth spurts and bone maturation, usually for reasons we don't understand.