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Answer Wiki. Summary: peak running performance after donating blood may be impacted for up to 1-2 weeks after donating 1 pint of blood, but is most noticeably impacted within the first 1-2 days after donating when attempting to perform at peak levels during endurance activities.
Physically small people are not acceptable as blood donors as they have lower blood volumes and may not be able to safely lose a full pint of blood. One may not donate blood while one has the flu. But one can donate blood after exposure to someone with the flu provided the potential donor feels and has no symptoms. A minimum age limit exists as to how old a person must be in order to donate blood (usually age 17). There is no maximum age limit. Pregnancy and recent childbirth rule one out as a blood donor.