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1 Epstein-Barr virus (EBV) is a contagious infection that causes infectious mononucleosis. 2  The illness is spread by casual contact, usually via saliva. 3  Mono has an incubation period of 4 to 6 weeks. The illness is spread by casual contact, usually via saliva. 2  Mono has an incubation period of 4 to 6 weeks. 3  The vast majority of adults have antibodies against EBV, meaning they have been infected with the virus and are immune to mono.
The preclinical or asymptomatic phase, also called the incubation period, lasts between possibly 5 to 20 years following initial exposure. The clinical stage lasts an average of 12 months. The symptoms of kuru are divided into three specific stages. The first, ambulant stage, exhibits unsteady stance and gait, decreased muscle control, tremors, and dysarthria. In the second, sedentary stage, the patient is incapable of walking without support and suffers ataxia and severe tremors.