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1 Scabies is an itchy, highly contagious skin disease caused by an infestation by the itch mite Sarcoptes scabiei. 2  Direct skin-to-skin contact is the mode of transmission.3  A severe and relentless itch is the predominant symptom of scabies. Signs and symptoms of scabies include a skin rash composed of small red bumps and blisters that affects specific areas of the body. 2  Other symptoms can include tiny red burrows on the skin and relentless itching. 3  The itch leads to frequent scratching, which may predispose the skin to secondary infections.
The action of the mites moving within the skin and on the skin itself produces an intense itch that may resemble an allergic reaction in appearance.A delayed type IV hypersensitivity reaction to the mites, their eggs, or scybala (packets of feces) occurs approximately 30 days after infestation.ther mammals, such as wild and domesticated dogs and cats (in which it is one cause of mange) as well as ungulates, wild boars, bovids, wombats, koalas, and great apes are affected. The discovery of the itch mite in 1687 marked scabies as the first disease of humans with a known cause.