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The blastula precedes the formation of the gastrula in which the germ layers of the embryo form. A common feature of a vertebrate blastula is that it consists of a layer of blastomeres, known as the blastoderm, which surrounds the blastocoele. blastula is a sphere of cells surrounding a blastocoele. The blastocoele is a fluid filled cavity which contains amino acids, proteins, growth factors, sugars, ions and other components which are necessary for cellular differentiation.