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One common cause of muscle aches and pain is fibromyalgia, a condition that causes tenderness in your muscles and surrounding soft tissue, sleep difficulties, fatigue, and headaches.
The most common causes of muscle pain are tension, stress, overuse and minor injuries. This type of pain is usually localized, affecting just one or more muscles or parts of your body. Systemic muscle pain, which you feel throughout your body, is different.It's more often the result of an infection, an illness or a side effect of a medication. Common causes of muscle pain include: 1  Chronic exertional compartment syndrome. 2  Chronic fatigue syndrome.3  Claudication.4  Delayed-onset muscle soreness (DOMS).ystemic muscle pain, which you feel throughout your body, is different. It's more often the result of an infection, an illness or a side effect of a medication. Common causes of muscle pain include: 1  Chronic exertional compartment syndrome. 2  Chronic fatigue syndrome. 3  Claudication. 4  Delayed-onset muscle soreness (DOMS).