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1 Achalasia. 2  Achalasia is a condition that affects the smooth muscle portion of the esophagus, that is, the lower esophagus and the lower esophageal sphincter. 3  Specifically, the peristaltic wave disappears, and the lower sphincter does not relax.
Muscular dystrophy (MD) refers to a group of genetic diseases described by progressive dysfunction and/or weakness of skeletal muscles.uscles in charge of eye closure, facial expression, talking, swallowing, breathing, and moving upper or lower extremities might be involved to various extents in different kinds of muscular dystrophies. Some muscular dystrophies also affect the heart muscle causing cardiomyopathy or dysrhythmias.