2 doctors agreed: CFTR: Cystic fibrosis is caused by a mutation of the cftr gene, or cystic fibrosis transmembrane regulator, on chromosome 7. Cftr works as a chloride ion channel which helps to regulate chloride and sodium movement in your lungs and sweat ducts. ...Read more.
1. JKJones (Pharmacist (Verified)) - 11 / 08 / 2010. Desquamation is the natural shedding and peeling of the outermost layers of the skin. When there is damage to the skin or this process is interrupted or changed, there may be additional shedding and peeling.
Urea dissolves the intercellular matrix of the cells of the stratum corneum, promoting desquamation of scaly skin, eventually resulting in softening of hyperkeratotic areas. In nails, urea causes softening and eventually debridement of the nail plate.