The most common side effects of Wellbutrin are agitation, dry mouth, insomnia, headache, nausea, constipation, stomach pain, dizziness, ringing in the ears, vision problems, loss of interest in sex, sore throat, muscle pain, itching or skin rash, increased sweating, increased urination, and tremor.
Pfeiffer syndrome is a genetic disorder characterized by the premature fusion of certain skull bones (craniosynostosis).This early fusion prevents the skull from growing normally and affects the shape of the head and face. Pfeiffer syndrome also affects bones in the hands and feet. mutation in either the FGFR1 or FGFR2 gene alters protein function and causes prolonged signaling, which can promote the premature fusion of skull bones and affect the development of bones in the hands and feet. Type 1 Pfeiffer syndrome is caused by mutations in either the FGFR1 or FGFR2 gene.
The most common problems arise in the skin and eyes, and later in blood vessels in the form of premature atherosclerosis. PXE is caused by autosomal recessive mutations in the ABCC6 gene on the short arm of chromosome 16 (16p13.1).he first description of PXE that distinguished it from other xanthomatous conditions was by Dr Ferdinand-Jean Darrier in 1896. The eponym Groenblad-GrÃ¶nblad strandberg syndrome is used in older, literature after two physicians who made further discoveries in the disease. manifestations