Providers and consumers should realize that isotretinoin is a potent drug with the potential to cause birth defects and reserve its use for severe recalcitrant nodular acne. Isotretinoin is not for use in mild forms of acne and should not be shared among family members.
Most orbital motorways (or beltways) are purpose-built major highways around a town or city, typically without either signals or road or railroad crossings. In the United States, beltways are commonly parts of the Interstate Highway System. Similar roads in the United Kingdom are often called orbital motorways.
The term highway may conjure images of an endless, unchanging road, dotted by the same fast food restaurants and gas stations every few miles. But just as automakers have made endless variations of vehicles, road builders have come up with a lot of ways to get from here to there. These eleven highways from all over the world are by turns high speed, beautiful, enormous, and deadly, and they are all worth a drive.