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The pancreas /ËpÃ¦ÅkriÉs/ is a glandular organ in the digestive system and endocrine system of vertebrates. In humans, it is located in the abdominal cavity behind the stomach. It is an endocrine gland producing several important hormones, including insulin, glucagon, somatostatin, and pancreatic polypeptide which circulate in the blood.
pancreas. 1  a large, elongated, racemose gland located in the anterior abdomen between the liver, kidneys, stomach, spleen and duodenum. 2  The pancreas is composed of both exocrine and endocrine tissue. 3  The endocrine functions of the pancreas are related to the islets of Langerhans which occur throughout the pancreas.