Prevalence of vitamin A deficiency. Vitamin A deficiency (VAD) is a lack of vitamin A in humans. It is common in poorer countries but rarely seen in more developed countries. Nyctalopia (night blindness) is one of the first signs of VAD.revalence of vitamin A deficiency. Vitamin A deficiency (VAD) is a lack of vitamin A in humans. It is common in poorer countries but rarely seen in more developed countries. Nyctalopia (night blindness) is one of the first signs of VAD.
Both lithium and valproate have been reported to increase rat CSF GABA levels. Regarding valproate, animal studies reported that it enhances GABA levels, GABA synaptic release, GAD activity, neuronal GABA responsiveness, and inhibits GABA-T in several brain regions.
GABA is the most abundant calming (inhibiting) neurotransmitter in the body. It's also found throughout the brain and many internal organs. Valium and other benzodiazepines mimic GABA's action in the central nervous system (CNS.) Again,formed by enzymatic action from glutamic acid, 6,7 GABA is a specific for anxiety.