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Buerger's disease is an inflammation of the arteries, veins, and nerves in the legs, principally, leading to restricted blood flow. Left untreated, Buerger's disease can lead to gangrene of the affected areas. Buerger's disease is also known as thromboangitis obliterans.
In most cases, the first sign of Buergerâs disease is extreme pain in the lower arms and/or legs while at rest. Affected individuals may also experience cramping in the legs when they walk that, in rare cases, may cause affected individuals to limp (claudication).