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Myelodysplastic syndromes (MDS). 1  Is a diagnosis of cancer. 2  Is a group of diseases of the blood and bone marrow, with varying degrees of severity, treatment needs and life expectancy. 3  May be primary (de novo) or treatment-related. 4  Primary MDS has no obvious cause.
The different types of myelodysplastic syndromes are diagnosed based on certain changes in the blood cells and bone marrow. Age and past treatment with chemotherapy or radiation therapy affect the risk of a myelodysplastic syndrome. Signs and symptoms of a myelodysplastic syndrome include shortness of breath and feeling tired. Tests that examine the blood and bone marrow are used to detect (find) and diagnose myelodysplastic syndromes. Certain factors affect prognosis and treatment options.