Organomegaly involves the enlargement of body organs. Many different factors may cause such enlargement. While some causes are benign, others are more serious. Heart enlargement, liver enlargement, and spleen enlargement â called cardiomegaly, hepatomegaly, and splenomegaly, respectively â represent three examples of abnormal organ enlargement.
Thumb pain can result from damage or injury to any of the structures in your thumb, including bones, joints, tendons, nerves, muscles, blood vessels, connective tissue, skin or fingernails. The symptoms may be constant or they may vary, and they may improve or worsen with movement.
Thickening of the tendons can cause pain and tenderness along the thumb side of the wrist, which is noticeable when forming a fist, grasping or gripping things, or when turning the wrist. People may also feel a catching or snapping sensation when moving the thumb. The pain and swelling may make movement difficult.