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Silicone caulk generally cures within 24 hours. If it has been over 24 hours, check the silicone caulk Use By date on the package. If the product is older than the Use by date printed on the product, safely dispose of the product.It is too old and will not cure.ilicone caulk generally cures within 24 hours. If it has been over 24 hours, check the silicone caulk Use By date on the package. If the product is older than the Use by date printed on the product, safely dispose of the product.
It takes about 24 hours for acrylic latex caulk to cure completely. Silicone and modified silicone caulk cures in 12 to 48 hours, and polyurethanes take between three and 10 days to cure completely.All of these curing times will vary slightly depending on the temperature and humidity in your area.ilicone and modified silicone caulk cures in 12 to 48 hours, and polyurethanes take between three and 10 days to cure completely. All of these curing times will vary slightly depending on the temperature and humidity in your area.