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White blood cells known as lymphocytes arise from by mitosis of stem cells in the bone marrow. Some lymphocytes migrate to the thymus and become T cells that circulate in the blood and are associated with the lymph nodes and spleen.
Lymphocytes, the primary cells of the lymphatic system, make up roughly one-fourth of all white blood cells in the body. Like other white blood cells, they are produced in the red bone marrow. Lymphocytes constantly travel throughout the body, moving through tissues or through the blood or lymph vessels.