Related Terms. 1  annual gross income. 2  exclusion ratio. 3  gift tax. 4  creditable coverage. 5  annual exclusion. 6  mutually exclusive investment decisions. 7  foreign housing exclusion. 8  mutual exclusion doctrine. 9  low exercise price option (LEPO). 10  foreign earned income exclusion.
Methaqualone was first synthesized in India in 1955 by scientists trying to find a cure for malaria. The drug was ineffective against the disease, but not as a central nervous system depressant â and if a user could resist its sedative effects, a user could get high.
The sedativeâhypnotic activity of methaqualone was first noted by researchers in the 1950s. In 1962, methaqualone was patented in the US by Wallace and Tiernan. Its use peaked in the early 1970s as a hypnotic, for the treatment of insomnia, and as a sedative and muscle relaxant.