Trulicity 1.5 mg solution for injection. Each pre-filled syringe contains 1.5 mg of dulaglutide* in 0.5 ml solution. *Produced in CHO cells by recombinant DNA technology. For the full list of excipients, see section 6.1.
Frostbite is the medical condition in which localized damage is caused to skin and other tissues due to freezing. Frostbite is most likely to happen in body parts farthest from the heart and those with large exposed areas.The initial stages of frostbite are sometimes called frostnip.he several classifications for tissue damage caused by extreme cold include: 1  Frostnip is a superficial cooling of tissues without cellular destruction. 2  Chilblains are superficial ulcers of the skin that occur when a predisposed individual is repeatedly exposed to cold.
Frostbite develops when the fluid inside skin and tissue cells freezes and crystallizes. This blocks the blood flowing to the area, causing tissue damage. Frostbite can occur in the feet, toes, nose, ears, hands, and fingers. During its early stages, the skin will turn red and it will sting, burn, or feel cold. As time passes, the skin may discolor to a yellowish gray or white, and it may turn waxy. It may also throb, swell, or become numb.