Organomegaly involves the enlargement of body organs. Many different factors may cause such enlargement. While some causes are benign, others are more serious. Heart enlargement, liver enlargement, and spleen enlargement â called cardiomegaly, hepatomegaly, and splenomegaly, respectively â represent three examples of abnormal organ enlargement.
Thumb pain can result from damage or injury to any of the structures in your thumb, including bones, joints, tendons, nerves, muscles, blood vessels, connective tissue, skin or fingernails. The symptoms may be constant or they may vary, and they may improve or worsen with movement.
De Quervain's tendinosis occurs when the tendons around the base of the thumb are irritated or constricted. The word tendinosis refers to a swelling of the tendons. Swelling of the tendons, and the tendon sheath, can cause pain and tenderness along the thumb side of the wrist. This is particularly noticeable when forming a fist, grasping or gripping something, or when turning the wrist. Anatomy.