Figure 3: Vasodilation produced by the direct effects of caffeine on the VSMC. Caffeine inhibits the voltage-dependent Ca2+ channels and the entrance of calcium to the cytoplasm. In addition, it inhibits the IP3 receptor and increases the ânon-contractile Ca2+.
Instructions. 1. Fill the bottom of the pan with a layer of water. 2. Add the vinegar. 3. Bring the pan to the boil. It should be looking a bit cleaner already. 4. Remove the pan from the heat and add the baking soda. Expect fizz! 5.Empty the pan and scour as normal; if necessary add an extra bit of dry baking soda.6. If there are any super stubborn marks that don't come off with scouring, make a paste of baking soda and a couple of drops of water.. Remove the pan from the heat and add the baking soda. Expect fizz! 5. Empty the pan and scour as normal; if necessary add an extra bit of dry baking soda. 6. If there are any super stubborn marks that don't come off with scouring, make a paste of baking soda and a couple of drops of water.
1 You can also add a little water to the baking soda to achieve a paste-like consistency. 2  If you're really having trouble with burn marks, try a mildly-abrasive cleaner, such as Bar Keeper's Friend. 3  Just sprinkle a generous amount onto the bottom of your pan and add a little water to form a paste.f you hand dry your pans, water spots are not likely to be a problem. If they occur, swish some club soda around in each pan. Rinse them off, and then wipe them dry with a clean cloth. 1  Alternatively, you can try soaking the pan in vinegar, then clean as usual with a mild detergent and soft cloth.