Immune system diseases (If you have kidney disease due to lupus, your doctor will call it lupus nephritis.) Long-lasting viral illnesses, such as HIV/AIDS, hepatitis B, and hepatitis C. Pyelonephritis, a urinary tract infections within the kidneys, which can result in scarring as the infection heals.
By Dr Ananya Mandal, MD. Nicotine has strong mood altering effects and can act on the brain as both a stimulant and a relaxant. Once within the bloodstream, nicotine may circulate around the body until it reaches the brain.
Recent research has shown how nicotine acts on the brain. Nicotine activates the circuitry that regulates feelings of pleasure, the so-called reward pathways. Research has shown that nicotine increases the levels of dopamine (a key brain chemical involved in mediating the desire to consume drugs) in the reward circuits of the brain. Nicotine's pharmacokinetic properties have been found to enhance its abuse potential. Smoking cigarettes produces a rapid distribution of nicotine to the brain, with drug levels peaking within 10 seconds of inhalation.