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endogenous definition: The definition of endogenous is coming from the inside. (adjective) An example of something endogenous is a tumor that is caused by conditions inside the body not by externally-introduced conditions such as smoking. ...
An endogenous agonist for a particular receptor is a compound naturally produced by the body that binds to and activates that receptor. For example, the endogenous agonist for serotonin receptors is serotonin, and the endogenous agonist for dopamine receptors is dopamine. Full agonists bind to and activate a receptor with the maximum response that an agonist can elicit at the receptor. One example of a drug that can act as a full agonist is isoproterenol, which mimics the action of adrenaline at Î² adrenoreceptors.