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Chest Pain, Acute. Severe, sudden chest pain can represent a life-threatening problem. Follow this chart for more information. Our trusted Symptom Checker is written and reviewed by physicians and patient education professionals. Find a possible diagnosis by choosing a symptom and answering a few simple questions.
1 Pulmonary embolism. This cause of chest pain occurs when a blood clot becomes lodged in a lung (pulmonary) artery, blocking blood flow to lung tissue.  Pleurisy. If the membrane that covers your lungs becomes inflamed, it can cause chest pain that's made worse when you inhale or cough.