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The drugâs initial approval noted mild side effects such as vomiting, itching, lethargy and diarrhea. Some 70 million doses of Trifexis have been distributed through 15,000 veterinary clinics, said Elanco spokeswoman Julie Lawless.
Trismus is defined in Taber's Cyclopedic Medical Dictionary as a tonic contraction of the muscles of mastication. In the past, this word was often used to describe the effects of tetanus, also called 'lock-jaw'.he most obvious effect of trismus is difficulty in opening the mouth. As discussed above, in cancer patients this frequently results from scar tissue from radiation or surgery, nerve damage, or a combination of factors. In stroke patients, the general cause is central nervous system dysfunction.