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Losartan can be administered once or twice daily at total daily doses of 25 to 100 mg. If the antihypertensive effect measured at trough using once-aday dosing is inadequate, a twice-a-day regimen at the same total daily dose or an increase in dose may give a more satisfactory response.
Losartan, sold under the trade name Cozaar among others, is a medication mainly used to treat high blood pressure. Other uses include for diabetic kidney disease, heart failure, and left ventricular enlargement. It is taken by mouth. It may be used together with other blood pressure medication. Up to six weeks may be required for the full effects to occur. Common side effects include muscle cramps, stuffy nose, cough, and high blood potassium. Severe side effects may include angioedema, low bloo