The most common and severe form of Î±1-antitrypsin deficiency is caused by the Z mutation, a single base substitution (Gul342-Lys) in the Î±1-antitrypsin gene. Misfolding of proteins during synthesis can initiate an ordered polymerization, which leads to aggregation of the protein within the cell.
Main article: List of place names of Native American origin in California. 1  Malibu â from VentureÃ±o <Umalibu>, perhaps reflecting [(hu)maliwu], it (the surf) makes a loud noise all the time over there. 2  Pismo Beach - from Chumash Pismu for tar. 3  Simi Valley â from VentureÃ±o <Simiyi>.
1 List of placenames of indigenous origin in the Americas. 2  List of federally recognized tribes by state: As of May 2013, there were 566 Native American tribes legally recognized by the U.S. Government, according to the article,  List of federally recognized tribes 3  .. Native Americans in the United States. Seminole County, Florida: Seminole is named after the Seminole Native American tribe. 2  Tallahassee â from the name of a Creek town, talaha:talahÃ¡, ssi perhaps (from)i, talwa tÃ¡lwa + tribal:town, aha, ahÃ¡.  ssi old rancid