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The calculation of minute ventilation is simple: MV=TV*Rf or minute volume is equal to tidal volume (amount of air for one breath, ml) multiplied by the respiratory frequency (number of breaths per minute). This table shows normal minute ventilation (liters of air per minute) in healthy subjects at rest (14 studies).
There is an increase in tidal volume (almost 50%), which causes an increase in minute ventilation throughout pregnancy (21% and 50% in the second and third trimesters respectively) (Artal et al., 1986; OâToole, 2003).