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When someone gets HIV, the body's immune system makes antibodies to try to fight the infection. Most HIV tests available today test for HIV antibodies. If HIV antibodies are present, it means that a person is infected with HIV. One type of HIV test detects the virus itself. This is called an RNA test. RNA testing is more expensive and much less common than antibody tests.
The HIV test is designed to detect antibodies to HIV in your blood or saliva. Antibodies are proteins produced by your body when you have an infection and they help fight infection. If you are infected with HIV, your body makes very specific antibodies to fight the infection. The HIV antibodies are different from antibodies for the flu, hepatitis, or other infections.