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Definition. Breast calcifications are calcium deposits within breast tissue. They appear as white spots or flecks on a mammogram and are usually so small that you can't feel them. Breast calcifications are common on mammograms and they're especially prevalent after menopause.n a mammogram, breast calcifications can appear as macrocalcifications or microcalcifications. 1  Macrocalcifications. 2  These show up as large white dots or dashes. 3  They're almost always noncancerous and require no further testing or follow-up.
Calcium can also be released into the blood when cancer spreads (metastasizes) to bone and destroys bone cells. Such bone destruction occurs most commonly with prostate, breast, and lung cancers. Multiple myeloma (a cancer involving bone marrow) can also lead to the destruction of bone and result in hypercalcemia.