Immune system diseases (If you have kidney disease due to lupus, your doctor will call it lupus nephritis.) Long-lasting viral illnesses, such as HIV/AIDS, hepatitis B, and hepatitis C. Pyelonephritis, a urinary tract infections within the kidneys, which can result in scarring as the infection heals.
By Dr Ananya Mandal, MD. Nicotine has strong mood altering effects and can act on the brain as both a stimulant and a relaxant. Once within the bloodstream, nicotine may circulate around the body until it reaches the brain.
After the nicotine is gone, and the brain stops releasing the positive neurotransmitters, smokeless tobacco users feel tired, depressed, and down. Nicotine also causes the brain to release a chemical called dopamine. Other very addictive drugs like cocaine make the brain release dopamine, too.