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endogenous definition: The definition of endogenous is coming from the inside. (adjective) An example of something endogenous is a tumor that is caused by conditions inside the body not by externally-introduced conditions such as smoking. ...
Definition of endogenous. 1  1 : growing or produced by growth from deep tissue endogenous plant roots. 2  2a : caused by factors inside the organism or system suffered from endogenous depression endogenous business cyclesb : produced or synthesized within the organism or system an endogenous hormone.