The most common and severe form of Î±1-antitrypsin deficiency is caused by the Z mutation, a single base substitution (Gul342-Lys) in the Î±1-antitrypsin gene. Misfolding of proteins during synthesis can initiate an ordered polymerization, which leads to aggregation of the protein within the cell.
Main article: List of place names of Native American origin in California. 1  Malibu â from VentureÃ±o <Umalibu>, perhaps reflecting [(hu)maliwu], it (the surf) makes a loud noise all the time over there. 2  Pismo Beach - from Chumash Pismu for tar. 3  Simi Valley â from VentureÃ±o <Simiyi>.
1 AHOTE: Native American Hopi name meaning restless one.. 2  AHTAHKAKOOP: Native American Cree name meaning star blanket.. 3  AMITOLA: Native American Sioux name meaning rainbow.. 4  This name comes from a legend that says that the first colorful picture was painted on the clouds by a young Indian chief named Amitola. MUATA: Native American Miwok name meaning yellow jackets inside a nest.. 2  MUKKI: Native American Algonquin name meaning child.. 3  MUNDOO: Native American Algonquin name for the Great Spirit, but it was applied to the devil by the first Christian missionaries.