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Symptoms associated with Tay-Sachs disease may include an exaggerated startle response to sudden noises, listlessness, loss of previously acquired skills (i.e., psychomotor regression), and severely diminished muscle tone (hypotonia).ay Sachs Disease. Important. It is possible that the main title of the report Tay Sachs Disease is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Tay-Sachs is a disease that is the result of a genetic mutation; it is fatal and affects the central nervous system. It is the result of the HEXA gene, located on chromosome 15; what occurs is that children have the deficiency of the enzyme, Hex X.here are two different kinds of this; infantile tay-sachs disease and late onset of tay-sachs disease. Infantile Tay-Sachs starts to show signs when the infant is around six months old; by age two, most children with this condition have seizures and decreasing mental state.