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The drugâs initial approval noted mild side effects such as vomiting, itching, lethargy and diarrhea. Some 70 million doses of Trifexis have been distributed through 15,000 veterinary clinics, said Elanco spokeswoman Julie Lawless.
What is Trifexis? Trifexis is a 3-way parasite protection against fleas, heartworm, and intestinal worms available in a monthly chewable tablet. Who is it for? Trifexis is for use in dogs and puppies 8 weeks of age or older and 5 lbs of body weight or greater.