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Manganese is a part of many enzyme systems, including the enzymes involved in blood sugar control, energy metabolism, and thyroid hormone function. Manganese also participates in the antioxidant enzyme, superoxide dismutase, or SOD.
Manganese occurs in the body principally in the liver, but it is also present in appreciable amounts in the kidneys, pancreas, and bone. The lowest concentrations are found in skeletal muscle. Function of manganese.