Organomegaly involves the enlargement of body organs. Many different factors may cause such enlargement. While some causes are benign, others are more serious. Heart enlargement, liver enlargement, and spleen enlargement â called cardiomegaly, hepatomegaly, and splenomegaly, respectively â represent three examples of abnormal organ enlargement.
Thumb pain can result from damage or injury to any of the structures in your thumb, including bones, joints, tendons, nerves, muscles, blood vessels, connective tissue, skin or fingernails. The symptoms may be constant or they may vary, and they may improve or worsen with movement.
This phenomenon, known as peripheral neuropathy, can also sometimes cause hand pain. DeQuervain's disease is a swelling and inflammation of the tendon around the thumb, causing pain in the thumb and lower arm. Trauma or injury to any of the structures in the hand is another common cause of hand pain. Medically Reviewed by a Doctor on 3/2/2017.