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A child with Kohlerâs disease may present similarly to a child with a foot injury. An examination will reveal pain and tenderness over the dorsomedial midfoot, with or without local skin changes. Affected children typically walk with a limp or antalgic gait, with weight bearing on the lateral side of the foot.
Hirschsprung's disease is a birth defect that affects the nerve cells in the large intestine. These nerve cells control the muscles that normally push food and waste through the large intestine.In babies who have Hirschsprung's disease, the muscles in the wall of the large intestine don't relax, which prevents stool from passing.This can lead to trapped stool, infection, pain and swelling, and bowel problems. doctor may think that a child has the disease based on the child's symptoms and the results of a physical exam. Other tests may be done to confirm the diagnosis, such as: 1  A tissue sample from the rectum (biopsy) . 2  An abdominal X-ray. 3  An X-ray of the large intestine (barium enema) . 4  Anorectal manometry.