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There was also a second physician named Bernard Sachs who recognized the familial nature of the disorder and also observed numerous cases. He witnessed that Tay Sachs disease was most common in the European, Jewish origin. Â· When was Tay Sachs disease discovered?Tay Sachs disease was discovered in the year of 1880.
Research in the late 20th century demonstrated that TayâSachs disease is caused by a genetic mutation in the HEXA gene on (human) chromosome 15.A large number of HEXA mutations have been discovered, and new ones are still being reported. Adult/Late-Onset TayâSachs disease. 2  A rare form of this disease, known as Adult-Onset or Late-Onset TayâSachs disease, usually has its first symptoms during the 30s or 40s. 3  In contrast to the other forms, late-onset TayâSachs disease is usually not fatal as the effects can stop progressing.