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Print This Page. Inflammation of an outgrowth to the tarsal navicular bone is called Kohler disease. This condition occurs most commonly in children two to nine years of age. Children with Kohler disease present with unilateral foot pain and tenderness to light pressure/touch over the tarsal navicular bone. For more information or to schedule an appointment, call 314.454.5437 or 800.678.5437 or email us.
General Information About Langerhans Cell Histiocytosis (LCH). The histiocytic diseases in children and adults include three major classes of disorders. Only Langerhans cell histiocytosis (LCH), a dendritic cell disorder, is discussed in detail in this summary.Erdheim-Chester disease (primarily found in adults) and juvenile xanthogranuloma (diagnosed in children and adults) are macrophage disorders.he natural history of disease in adult Langerhans cell histiocytosis (LCH), with the exception of pulmonary LCH, is unknown. It is unclear whether there are significant differences from childhood LCH, although it appears that multisystem-risk LCH is less aggressive than childhood high-risk disease.