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The calculation of minute ventilation is simple: MV=TV*Rf or minute volume is equal to tidal volume (amount of air for one breath, ml) multiplied by the respiratory frequency (number of breaths per minute). This table shows normal minute ventilation (liters of air per minute) in healthy subjects at rest (14 studies).
Elimination of carbon dioxide from the alveoli is directly proportional to alveolar minute ventilation (see the image below), which is determined by the product of tidal volume (minus dead-space ventilation) and frequency as follows: Alveolar minute ventilation = (tidal volume â dead space) Ã frequency.