It is taken to mean heart pain, although chest pain may be due to cramp, spasm in the chest wall muscles, acid flowing back from the stomach, inflammation of the lung surface (pleurisy), or the start of shingles.
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BRAF belongs to a family of serine-threonine that includes ARAF, BRAF, and CRAF (RAF1). RAF are central mediators in the MAP signaling cascade and exert their effect predominantly through and activation of MEK. This occurs following the (hetero- or homo-) of the RAF molecules.