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Kohlerâs disease is a rare condition in which the tarsal navicular bone (a bone in the arch of the foot) becomes inflamed. This bone disease is named after the German radiologist who described the condition in the early twentieth century. Kohlerâs disease usually affects children between the ages of three and five. It occurs more commonly in boys than in girls, and is often unilateral, affecting one foot. It is described as an avascular necrosis, or osteonecrosis, in which bone tissue deteriorates due to an interruption of blood supply.
Symptoms of chronic schistosomiasis infection are caused by the body s reaction to the parasites eggs, which become lodged in the intestine or bladder, causing inflammation or scarring. In children, infection can cause anemia, malnutrition, and learning difficulties.chistosomiasis, also known as bilharzia, is a chronic disease caused by parasitic worms that live in certain types of freshwater snails. People who come into contact with water that contains these snails are at risk of infection.