If one is talking about interstate business, a company that is in one state provides its products and services to a customer in another state or several states. Intrastate. Intrastate refers to anything that pertains to a single state and does not require crossing over the boundaries of a single state.
H. pylori was first discovered in the stomachs of patients with gastritis and ulcers in 1982 by Drs. Barry Marshall and Robin Warren of Perth, Australia. At the time, the conventional thinking was that no bacterium could live in the acid environment of the human stomach.
On the other hand, H. pylori infection is known to cause atrophic gastritis (chronic inflammation of the stomach leading to atrophy of the inner lining of the stomach). Some physicians believe that atrophic gastritis can lead to cell changes (intestinal metaplasia) that can be precursors to stomach cancer.