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1 Epstein-Barr virus (EBV) is a contagious infection that causes infectious mononucleosis. 2  The illness is spread by casual contact, usually via saliva. 3  Mono has an incubation period of 4 to 6 weeks. The illness is spread by casual contact, usually via saliva. 2  Mono has an incubation period of 4 to 6 weeks. 3  The vast majority of adults have antibodies against EBV, meaning they have been infected with the virus and are immune to mono.
: the period between the infection of an individual by a pathogen and the manifestation of the disease it causes Mono, which has an incubation period of 30 to 50 days, characteristically announces itself with headaches, fever, sore throat, tonsillitis, and extreme fatigue.âYour Health & Fitness, October/November 1986 Quarantines worked to control ...