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One common cause of muscle aches and pain is fibromyalgia, a condition that causes tenderness in your muscles and surrounding soft tissue, sleep difficulties, fatigue, and headaches.
Other Causes. While physical exertion that leads to DOMS is the most common cause of muscular soreness, other factors can lead to muscle aches and pains. Muscles, especially those in the back and neck, can become sore from poor posture while standing, sitting or sleeping.Sometimes viruses and diseases such as the flu, colds and other conditions cause aches in the muscles. Arthritis and infections can also irritate muscle tissue and lead to muscular aches.Muscle aches can even be caused by physiological conditions, such as depression or anxiety, and be exacerbated by lack of rest, malnutrition and drugs.rthritis and infections can also irritate muscle tissue and lead to muscular aches. Muscle aches can even be caused by physiological conditions, such as depression or anxiety, and be exacerbated by lack of rest, malnutrition and drugs.