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The pancreas /ËpÃ¦ÅkriÉs/ is a glandular organ in the digestive system and endocrine system of vertebrates. In humans, it is located in the abdominal cavity behind the stomach. It is an endocrine gland producing several important hormones, including insulin, glucagon, somatostatin, and pancreatic polypeptide which circulate in the blood.
The head of the pancreas is located on the right side of the abdomen, is the largest part of the organ, and is nestled in the duodenum. The duodenum is the first part of the small intestine and extends immediately from the stomach. The body of the pancreas extends across the spine and is in the midline of the abdomen.