Providers and consumers should realize that isotretinoin is a potent drug with the potential to cause birth defects and reserve its use for severe recalcitrant nodular acne. Isotretinoin is not for use in mild forms of acne and should not be shared among family members.
Most orbital motorways (or beltways) are purpose-built major highways around a town or city, typically without either signals or road or railroad crossings. In the United States, beltways are commonly parts of the Interstate Highway System. Similar roads in the United Kingdom are often called orbital motorways.
California Vehicle Code, Sections 360, 590, define a highway as only a way open for use of motor vehicles, but the California Supreme Court has held that the definition of 'highway' in the Vehicle Code is used for special purposes of that act, and that canals of the Los Angeles neighborhood of Venice, California, are highways that are entitled to be maintained with state highway funds.