The opposite can be true; i.e., people with large muscle mass sometimes have elevated CK levels in the absence of any pathology. This particular enzyme falls into a category where an individual's own normal is more relevant than the normal range given for a population.
1 If the demand increases, and the supply remains the same, there will be a shortage. 2  This will mean the price will increase. 3  If the demand decreases, and the supply remains the same, there will be a surplus. 4  This will mean the price will go down.
If demand is inelastic (e <R> < 1) then R' will be negative, because to sell a marginal (infinitesimal) unit the firm would have to lower the selling price so much that it would lose more revenue on the pre-existing units than it would gain on the incremental unit.