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Ulcerative colitis causes swelling in the large intestine and can lead to cramping, diarrhea, and more. Celiac disease Celiac disease, which is an intestinal reaction to gluten, can cause gas, diarrhea, bloating, and weight loss.
Because microscopic colitis generally is a benign disorder that does not lead to serious consequences such as weight loss or malnutrition, an approach to treatment must consider the severity of the symptoms, particularly when using therapies with potential toxicities.