Definition of inference for English Language Learners. : 1  the act or process of reaching a conclusion about something from known facts or evidence. : 2  a conclusion or opinion that is formed because of known facts or evidence.
Causes of Clogged Arteries. There are many substances and properties that can circulate with the blood, including cholesterol, calcium, fat, fibrin and cellular waste. When these substances accumulate on the inner walls of the arteries, they turn into plaque buildup.
In many instances, clogged arteries do not cause any symptoms until a major event, such as a heart attack or stroke, occurs. The first symptom, chest pain, is also called angina. It may result from reduced blood flow to the heart. That reduced blood flow is caused by plaque in the arteries leading to the heart.