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Ulcerative colitis causes swelling in the large intestine and can lead to cramping, diarrhea, and more. Celiac disease Celiac disease, which is an intestinal reaction to gluten, can cause gas, diarrhea, bloating, and weight loss.
Less common causes. â Inflammatory bowel disease, also known as Crohn disease or ulcerative colitis, is a chronic inflammatory condition in which the lining of the digestive tract becomes inflamed. The inflammation leads to symptoms, such as bloody stools, diarrhea, lack of appetite, and weight loss.