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Answer Wiki. Summary: peak running performance after donating blood may be impacted for up to 1-2 weeks after donating 1 pint of blood, but is most noticeably impacted within the first 1-2 days after donating when attempting to perform at peak levels during endurance activities.
Most people feel great after giving blood. If you feel any abnormal symptoms, let a staff member at the blood donation center or blood drive know. You should avoid lifting heavy objects or strenuous exercise for the next 24 hours; otherwise you can resume full activity as long as you feel well.