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1 Achalasia. 2  Achalasia is a condition that affects the smooth muscle portion of the esophagus, that is, the lower esophagus and the lower esophageal sphincter. 3  Specifically, the peristaltic wave disappears, and the lower sphincter does not relax.
Although we often think of skeletal muscle spasms or cramps, other kinds of muscle, such as smooth muscle, can spasm or cramp. Smooth muscles are found in the walls of hollow organs in your body, such as your stomach, bladder, and blood vessels, and play an important role in normal organ function.uscle cramps are often caused by or worsened when you are dehydrated and not getting enough fluids. Muscle spasms and cramps can also be caused by neuromuscular disorders, such as multiple sclerosis or a spinal cord injury.