While lysine in the diet is considered safe, excessive doses may cause gallstones. There have also been reports of renal dysfunction, including Fanconi syndrome and renal failure. Talk to your doctor before taking supplemental lysine if you have kidney disease, liver disease, or if you are pregnant or breastfeeding.
Well I dont know about off premise sales, but on premise runs about like this...these are the general cost of sales numbers. Liquor 13%-17%. Beer (bottles)26%-31%. Beer (draft) 18%-26%. Wine-30%-47%. So the gross margin would be the reverse. Liquor 83%-87%.
As of 2014, the distillers' wholesale market revenue for bourbon sold within the U.S. is about $2.7 billion, and bourbon makes up about two-thirds of the $1.6 billion of U.S. exports of distilled spirits.