Giant axonal neuropathy is caused by mutations in the GAN gene, which provides instructions for making a protein called gigaxonin. Some GAN gene mutations change the shape of the protein, affecting how it binds to other proteins to form a functional complex.iant axonal neuropathy generally appears in infancy or early childhood. It progresses slowly as neuronal injury becomes more severe. Signs of giant axonal neuropathy usually begin in the peripheral nervous system, which governs movement and sensation in the arms, legs, and other parts of the body.
The Handmaid's Tale will enter production later this year, and premiere on Hulu in 2017. I am thrilled that MGM and Hulu are developing The Handmaid's Tale as a series, and extra thrilled that the very talented Elizabeth Moss will be playing the central character, Atwood said.
As usual, the Globes shone light on freshman series, with 15 landing nominations, half of them taking home multiple mentions: Big Little Lies, Feud, Huluâs The Handmaidâs Tale, Amazonâs The Marvelous Mrs. Maisel, USA Networkâs The Sinner, Showtimeâs SMILF and NBCâs Will & Grace.