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Answer Wiki. Summary: peak running performance after donating blood may be impacted for up to 1-2 weeks after donating 1 pint of blood, but is most noticeably impacted within the first 1-2 days after donating when attempting to perform at peak levels during endurance activities.
Before you give blood, you'll first have to complete a quick physical that measures your temperature, pulse, blood pressure, and hemoglobin levels. After your blood is collected, it's sent off to a lab where it will undergo 13 different tests for infectious diseases, like HIV and West Nile virus.