Registered nurses in the Sacramento metropolitan area averaged $51.79 per hour, and those in Salinas averaged $50.77. The average hourly wage was $50.21 in Napa, $49.51 in Santa Rosa, $48.45 in Modesto and $47.14 in the greater Santa Cruz area.
Ribonucleotide reductase (RNR), also known as ribonucleoside diphosphate reductase, is an enzyme that catalyzes the formation of deoxyribonucleotides from ribonucleotides.lass III reductases use a glycine radical generated with the help of an S-adenosyl methionine and an iron sulphur center. Reduction of NTPs is limited to anaerobic conditions. Class III reductases are distributed in archaebacteria, eubacteria, and bacteriophages.
ATF6 is an endoplasmic reticulum (ER) membrane-anchored transcription factor activated by regulated intramembrane proteolysis in the ER stress response. The release of the cytosolic transcription factor domain of ATF6 requires the sequential processing by the Golgi site-1 and site-2 proteases (S1P and S2P).owever, in the case of the bacterial substrate RseA and the intramembrane protease YaeL, specific glutamine-rich sequences in the luminal domain of RseA were required to block YaeL digestion (15). A third model is that cleavage by S1P could create a substrate site for S2P binding and cleavage.