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Myelodysplastic syndromes (MDS). 1  Is a diagnosis of cancer. 2  Is a group of diseases of the blood and bone marrow, with varying degrees of severity, treatment needs and life expectancy. 3  May be primary (de novo) or treatment-related. 4  Primary MDS has no obvious cause.
Definition. 1  Myelodysplastic syndromes (MDS) are a group of diseases that involve dysfunction of the bone marrow. Bone marrow is the tissue found within the bones; its task is to create mature blood cells from stem cells. 2  There are five types of MDS.