In addition, thiazolidinediones have several other potential side effects, which make them less appealing as initial or second step therapy. (See 'Cardiovascular effects' below and 'Safety' below.). The pharmacology and use of thiazolidinediones will be reviewed here.
Alcohol impairs brain areas such as the cerebellumâthe control site for your balance and coordinationâand your cerebral cortex, which is responsible for thinking, memory, and learning, says Kimberly S. Walitzer, Ph.D., deputy director of the University at Buffaloâs Research Institute on Addictions.
The primary mechanism by which alcohol affects brain function is  via its interaction with a class of inhibitory receptors, called  'GABA receptors' (GABA stands for Gamma-Aâ¦minoBuytric Acid, which is  a type of inhibitory neurotransmitter).