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Initial exposure can result in mild to severe symptoms. Queasiness and vomiting tend to be the most common, and a person may develop kidney stones or ulcers. Other intestinal symptoms of Agent Orange include jaundice, stomach pain, and liver irritation. These Agent Orange effects typically occur shortly after contact with the herbicide, although some people may not have any symptoms of exposure until well afterward.
Ischemic heart disease, linked to Agent Orange exposure, involves a reduction of blood flow and oxygen to the heart. Over time this type of heart disease can damage and weaken the muscles in the heart. Ischemic heart disease is one of the most common causes of heart failure.