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Uremia or uraemia (see spelling differences) can be translated as  urea in the blood.Urea is one of the primary components of urine. It can be defined as an excess of amino acid and protein metabolism end products, such as urea and creatinine, in the blood that would be normally excreted in the urine.The Uremic Syndrome can be defined as the terminal clinical manifestation of kidney failure (also called renal failure).It is the signs, symptoms and results from laboratory tests which result from inadequate excretory, regulatory and endocrine function of the kidneys.he Uremic Syndrome can be defined as the terminal clinical manifestation of kidney failure (also called renal failure). It is the signs, symptoms and results from laboratory tests which result from inadequate excretory, regulatory and endocrine function of the kidneys.
Topic Overview. Uremia (uremic syndrome) is a serious complication of chronic kidney disease and acute kidney injury (also known as acute renal failure). It occurs when urea and other waste products build up in the body because the kidneys are unable to eliminate them.These substances can become poisonous (toxic) to the body if they reach high levels. Prolonged or severe fluid buildup (edema) may make the uremic syndrome worse.remic syndrome may affect any part of the body and can cause: 1  Nausea, vomiting, loss of appetite, and weight loss. 2  Changes in mental status, such as confusion, reduced awareness, agitation, psychosis, seizures, and coma.