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Buerger's disease is an inflammation of the arteries, veins, and nerves in the legs, principally, leading to restricted blood flow. Left untreated, Buerger's disease can lead to gangrene of the affected areas. Buerger's disease is also known as thromboangitis obliterans.
Affected legs (or arms) can be pale, with blue/red discoloration, cold, painful, tingling or numb. Buergerâs disease usually develops in heavy male smokers (20-40 years of age) and cause pain, numbness and tingling in the feet and/or hands triggered by exercise and relieved by rest; ulcers on fingers/toes may appear.