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Smithville, Arkansas. From Wikipedia, the free encyclopedia. Smithville is a town in Lawrence County, Arkansas, United States. The population was 73 at the 2000 census.
Euro-American settlers first came to the area of Smithville in 1808. Smithville became the county seat of modern day Lawrence County in 1837. The county seat was later moved to Powhatan in 1869, after the Civil War. This was done in part to take advantage of riverboat commerce along Black River.