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Difference Between Physiological & Pathological Jaundice. Physiological and pathological jaundice both result in a yellow tint to the skin, whites of the eyes and mucous membranes but are caused by different conditions. Physiological Jaundice. When jaundice occurs in a healthy baby, it is considered physiological jaundice.
Jaundice is a yellow tint to a newborn's skin and the white part of the eyes. It is a sign that there's too much bilirubin in the baby's blood. The word for having too much bilirubin in the blood is hyperbilirubinemia (say hy-per-bil-ih-roo-bih-NEE-mee-uh). Jaundice usually appears in the first 5 days of life. Many babies have left the hospital by the time jaundice starts. So your doctor may want to do a follow-up exam when your baby is 3 to 5 days old. Most babies have mild jaundice. It usually gets better or goes away on its own within a week or two without causing problems. But jaundice should be taken seriously. In rare cases, if the bilirubin level stays high and isn't treated, it can cause brain damage called kernicterus.