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1 Sodium plays a large role in fluid balance, with different variations of sodium determining the shift of water by osmosis from one area of the body to another.  Along with chloride and bicarbonate, sodium is important for the proper regulation of the acid-base balance of the body.
Following is a list of some of the more important ions in the cells and fluids of our bodies: Sodium ions are the principal cations found outside cells in the body. They help regulate and control the level of body fluids. Too little leads to diarrhea, anxiety, a decrease in body fluids, and circulatory failure.