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1 Achalasia. 2  Achalasia is a condition that affects the smooth muscle portion of the esophagus, that is, the lower esophagus and the lower esophageal sphincter. 3  Specifically, the peristaltic wave disappears, and the lower sphincter does not relax.
smooth muscle contraction. -calmodulin is the protein used to bind calcium ions to skeletal muscle when its fibers are stimulated. -hormones can stimulate or inhibit contraction. -stretching of the muscle can cause contraction. -slower to contract and relax, but can forcefully contract longer with the same amount of ATP.