If one is talking about interstate business, a company that is in one state provides its products and services to a customer in another state or several states. Intrastate. Intrastate refers to anything that pertains to a single state and does not require crossing over the boundaries of a single state.
H. pylori was first discovered in the stomachs of patients with gastritis and ulcers in 1982 by Drs. Barry Marshall and Robin Warren of Perth, Australia. At the time, the conventional thinking was that no bacterium could live in the acid environment of the human stomach.
Scientists studying the genetics of H. pylori have found different strains (types) of the bacterium. Some strains of H. pylori appear to be more prone to cause ulcers and stomach cancer. Further research in this area may help doctors to intelligently select those patients who need treatment. Vaccination against H. pylori is unlikely to be available in the near future.