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Difference Between Physiological & Pathological Jaundice. Physiological and pathological jaundice both result in a yellow tint to the skin, whites of the eyes and mucous membranes but are caused by different conditions. Physiological Jaundice. When jaundice occurs in a healthy baby, it is considered physiological jaundice.
The most common type of jaundice is called Physiologic Jaundice, which can affect up to 60% of full term babies in the first week of life. It is caused by elevated bilirubin levels.Bilirubin is a substance created by the normal breakdown of red blood cells. Bilirubin is processed and removed by the liver.he most common type of jaundice is called Physiologic Jaundice, which can affect up to 60% of full term babies in the first week of life. It is caused by elevated bilirubin levels.