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(December 2013) Myalgia, or muscle pain, is a symptom of many diseases and disorders. The most common causes are the overuse or over-stretching of a muscle or group of muscles. Myalgia without a traumatic history is often due to viral infections.
Systemic muscle pain, which you feel throughout your body, is different. It's more often the result of an infection, an illness or a side effect of a medication. Common causes of muscle pain include: 1  Chronic exertional compartment syndrome. 2  Chronic fatigue syndrome. 3  Claudication. 4  Delayed-onset muscle soreness (DOMS). 5  Dermatomyositis. 6  Dystonia. 7  Fibromyalgia. 8  Hypothyroidism (underactive thyroid).