While lysine in the diet is considered safe, excessive doses may cause gallstones. There have also been reports of renal dysfunction, including Fanconi syndrome and renal failure. Talk to your doctor before taking supplemental lysine if you have kidney disease, liver disease, or if you are pregnant or breastfeeding.
Well I dont know about off premise sales, but on premise runs about like this...these are the general cost of sales numbers. Liquor 13%-17%. Beer (bottles)26%-31%. Beer (draft) 18%-26%. Wine-30%-47%. So the gross margin would be the reverse. Liquor 83%-87%.
Total number of beer breweries in operation in 2012: 1,753: Total number of beer breweries in operation in 2013: 1,927: Total amount of gallons in 1 barrel of beer: 31 gallons: Total amount of pints of beer the U.S. drinks annually: 50 billion pints: Total average price to buy a beer at a U.S. pub: $3.87: Total amount of dollars in beer revenue made each year in U.S. $196 billion: Total GDP of Columbia as a country: $196 billion: Total amount out of 25 swimming pools in the U.S. that U.S. drinks every year: 1 out of 25 swimming pools