Providers and consumers should realize that isotretinoin is a potent drug with the potential to cause birth defects and reserve its use for severe recalcitrant nodular acne. Isotretinoin is not for use in mild forms of acne and should not be shared among family members.
Most orbital motorways (or beltways) are purpose-built major highways around a town or city, typically without either signals or road or railroad crossings. In the United States, beltways are commonly parts of the Interstate Highway System. Similar roads in the United Kingdom are often called orbital motorways.
Interstate 610 (abbreviated I-610) is a freeway that forms a 38-mile-long (61 km) loop around the downtown sector of city of Houston, Texas. Interstate 610, colloquially known as The Loop, Loop 610, The Inner Loop, or just 610, traditionally marks the border between the inner city of Houston (inside the Loop) and its surrounding areas. It is the inner of the three Houston beltways, the other two being Beltway 8 (Sam Houston Tollway) and State Highway 99 (Grand Parkway), of which various segments are under construction or planning.