While lysine in the diet is considered safe, excessive doses may cause gallstones. There have also been reports of renal dysfunction, including Fanconi syndrome and renal failure. Talk to your doctor before taking supplemental lysine if you have kidney disease, liver disease, or if you are pregnant or breastfeeding.
Well I dont know about off premise sales, but on premise runs about like this...these are the general cost of sales numbers. Liquor 13%-17%. Beer (bottles)26%-31%. Beer (draft) 18%-26%. Wine-30%-47%. So the gross margin would be the reverse. Liquor 83%-87%.
$700-$1,000 per BBL. Brewpubs may become profitable with as little as 250 BBLs of annual beer sales if it is all sold at retail. A brewpub should target beer sales of at least 40% of gross sales. Production breweries generally require 3,000-5,000 barrels of annual sales at wholesale to become profitable.rewpubs may become profitable with as little as 250 BBLs of annual beer sales if it is all sold at retail. A brewpub should target beer sales of at least 40% of gross sales. Production breweries generally require 3,000-5,000 barrels of annual sales at wholesale to become profitable.