What causes wrinkled peeling fingertips? If you have fingertips peeling and wrinkling, you could be suffering from nerve insufficiency, occupational exposure or even diabetes. Peeling is one of the most common signs, usually visible on the toes and fingers.
Hypothyroidism occurs when your thyroid does not produce enough hormones, which can result in a slow metabolism marked by weight gain, fatigue and sluggishness. If you gain weight, your body will not effectively make energy from food and may contribute to a slowed metabolism.
But because metabolism is a natural process, your body has many mechanisms that regulate it to meet your individual needs. Only in rare cases do you get excessive weight gain from a medical problem that slows metabolism, such as Cushing's syndrome or having an underactive thyroid gland (hypothyroidism).