GFR is related inversely and nonlinearly to serum creatinine. Age, gender, and race all affect muscle mass and, in turn, serum creatinine. Both the MDRD Study and CKD-EPI equations include variables to account for serum creatinine variation with age, gender, and race.
When a nerve is stimulated, its cell membrane is depolarised so that the inside of the cell becomes less negative. The potential is conducted along the axon to the axon termin â¦ al.At the dendrite it stimulates the release of a chemical transmitter, which diffuses across a synapse.The transmitter binds to receptor sites on the postsynaptic cell membrane to stimulate the generation of another impulse.+ 4 others found this useful.t the dendrite it stimulates the release of a chemical transmitter, which diffuses across a synapse. The transmitter binds to receptor sites on the postsynaptic cell membrane to stimulate the generation of another impulse. + 4 others found this useful.
Nerve Signals. The nerve signal, or action potential, is a coordinated movement of sodium and potassium ions across the nerve cell membrane.Here's how it works: A disturbance (mechanical, electrical, or sometimes chemical) causes a few sodium channels in a small portion of the membrane to open. 2  Sodium ions enter the cell through the open sodium channels. 3  The positive charge that they carry makes the inside of the cell slightly less negative (depolarizes the cell).