GFR is related inversely and nonlinearly to serum creatinine. Age, gender, and race all affect muscle mass and, in turn, serum creatinine. Both the MDRD Study and CKD-EPI equations include variables to account for serum creatinine variation with age, gender, and race.
When a nerve is stimulated, its cell membrane is depolarised so that the inside of the cell becomes less negative. The potential is conducted along the axon to the axon termin â¦ al.At the dendrite it stimulates the release of a chemical transmitter, which diffuses across a synapse.The transmitter binds to receptor sites on the postsynaptic cell membrane to stimulate the generation of another impulse.+ 4 others found this useful.t the dendrite it stimulates the release of a chemical transmitter, which diffuses across a synapse. The transmitter binds to receptor sites on the postsynaptic cell membrane to stimulate the generation of another impulse. + 4 others found this useful.
Many nerve cells are of the basic type illustrated above. Some kind of stimulus triggers an electric discharge of the cell which is analogous to the discharge of a capacitor. This produces an electrical pulse on the order of 50-70 millivolts called an action potential. The electrical impulse propagates down the fiber-like extension of the nerve cell (the axon). The speed of transmission depends upon the size of the fiber, but is on the order of tens of meters per second - not the speed of light transmission that occurs with electrical signals on wires.