Scleritis (inflammation of sclera) is a strong indication of the underlying medical problem. It can be due to fungal, viral or parasitic infection, trauma, exposure to chemicals, poisonous gases or due to post-surgical complications.
Mast cells are granulated cells typically found in connective tissue. These cells mediate immune responses to foreign particles. In particular, they release large amounts of histamine and enzymes in response to antigen recognition.
This has also been shown to be the case in mast cells, which have been used increasingly as a model secretory system2. The secretory granules of mast cells contain several mediators3, some of which, such as histamine, are known to participate in many immune reactions and allergic diseases4,5.