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If you have celiac disease, eating gluten causes inflammation in your intestines. As a result, you may not absorb nutrients properly and may develop nutritional deficiencies. These can progress to problems such as iron-deficiency anemia, osteoporosis and infertility issues.
In someone with celiac disease, eating foods containing gluten causes a reaction in the villi of the small intestine. Villi are tiny, finger-like projections that line the inside of that organ. For a person with celiac disease, eating gluten flattens the villi and makes them unable to absorb nutrients effectively.