The Phase Gate Review methodology improves project effectiveness by reviewing all stages of the project from the initial selection process through the entire process of development to the final stages of closure.
Systemic hypertension, or high blood pressure, is associated with hypertensive vascular disease and is a problem that is widespread. The term systemic distinguishes the condition from a local high blood pressure as in pulmonary (lung) or portal hypertension (hepatic portal system).
Portal hypertension is associated with splenomegaly and hence hypersplenism and the development of collateral vessels lining the esophagus and stomach, producing varices. Esophageal varices and, less often, gastric varices are particularly prone to bleeding, which is often massive.