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Pulmonary edema facts. 1  Pulmonary edema is typically caused by filling of alveoli in the lungs by fluid leaking out of the blood. 2  Pulmonary edema may be caused by a number of cardiac or non-cardiac conditions.  Breathing difficulty is the main manifestation of pulmonary edema.
Pulmonary edema, or fluid in the lungs is a condition in which fluid fills the alveoli in the lungs. This fluid then leaks into the blood causing causing inflammation, which causes symptoms of shortness of breath and problems breathing, and poorly oxygenated blood. Health problems that cause pulmonary edema include heart failure, kidney failure, high altitude, and medications.