Scleritis (inflammation of sclera) is a strong indication of the underlying medical problem. It can be due to fungal, viral or parasitic infection, trauma, exposure to chemicals, poisonous gases or due to post-surgical complications.
Mast cells are granulated cells typically found in connective tissue. These cells mediate immune responses to foreign particles. In particular, they release large amounts of histamine and enzymes in response to antigen recognition.
Gastrin, secreted by the G cells in the antrum of the stomach in response to the presence of protein is the most potent stimulator of the Histamine/Acid complex. The gastrin is not only carried by the blood stream, but is also carried directly into the lumens of the gastric pits an has a direct stimulating action.