Scleritis (inflammation of sclera) is a strong indication of the underlying medical problem. It can be due to fungal, viral or parasitic infection, trauma, exposure to chemicals, poisonous gases or due to post-surgical complications.
Mast cells are granulated cells typically found in connective tissue. These cells mediate immune responses to foreign particles. In particular, they release large amounts of histamine and enzymes in response to antigen recognition.
HISTAMINE. Histamine is formed by decarboxylation of histidine. It is stored preformed in cytoplasmatic granules of mast cells and basophils. Mast cells in man are found in the loose connective tissue of all organs.They occur particularly around blood and lymph vessels around nerves, and are more abundant in the skin, upper and lower respiratory tract, gastrointestinal tract and reproductive mucosa.Mast cells comprise up to 2% of the alveolar tissue cells.They are found especially in the connective tissue beneath the airway basement membrane, the bronchial lumen, near submucosal blood vessels and glands throughout muscle bundles, and in the alveolar septa.hey occur particularly around blood and lymph vessels around nerves, and are more abundant in the skin, upper and lower respiratory tract, gastrointestinal tract and reproductive mucosa. Mast cells comprise up to 2% of the alveolar tissue cells.