They make up the cardiac pacemaker, that is, the natural pacemaker of the heart. In most humans, the concentration of pacemaker cells in the sinoatrial (SA) node is the natural pacemaker, and the resultant rhythm is a sinus rhythm. Sometimes an ectopic pacemaker sets the pace, if the SA node is damaged or if the electrical conduction system of the heart has problems.
Lobo is an extensible all-Java web browser and RIA platform. It supports HTML 4, Javascript (AJAX) and CSS 2 plus direct JavaFX and Java (Swing/AWT) rendering. Cobra is the web browser's renderer API; also a Javascript-aware HTML parser.
And now that Edge is close to release, we see that it already surpasses WebKit in HTML5 support: http://html5test.com/compare/browser/chrome-43/firefox-38/ie... On the JavaScript side of things, Edge is tied for Firefox as the leading implementer of ES6 features: http://kangax.github.io/compat-table/es6/. For a long time, Microsoft made a strategic decision to ignore the web, and that hurt a lot of things.