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Denis transfused the blood from a sheep to a 15-year old boy and later to a labourer, both of whom survived the transfusions. In 1818, British obstetrician James Blundell successfully transfused human blood to a patient who had hemorrhaged during childbirth. In 1901, Karl Landsteiner, an Austrian physician discovered the first human blood groups, which helped transfusion to become a safer practice.
Within 10 years, transfusing the blood of animals to humans becomes prohibited by law because of reactions. 1795 In Philadelphia, American physician Philip Syng Physick, performs the first human blood transfusion, although he does not publish this information. 1818 James Blundell, a British obstetrician, performs the first successful transfusion of human blood to a patient for the treatment of postpartum hemorrhage.