1 Coadministration with moderate CYP3A4 and/or PgP inhibitors: Reduce dose by 50%; administer every other day if dose reduction is required for patients receiving the lowest available strength and maintain trough concentrations of 5 to 15 ng/mL.
A pregnant mouse can give birth to six to 12 babies in one litter. A female mouse can become pregnant several times a year. One mouse couple can produce 40 or more babies in one year.
Some mice may haâ¦ve 5-6 litters per  year, each of 8-10 young, (potentially over 60 young in a year)  whereas a horse or cow will normally only have one borth, one  youngste per year.