GCSE Drama 4240 helps students develop an understanding of many creative and challenging activities. Candidates are free to choose any of the controlled assessment options offered in this specification, including: 1  devised thematic work. 2  improvisation. 3  physical theatre. 4  set design.
By Mayo Clinic Staff. Most of the time, no apparent cause for night leg cramps can be identified. In general, night leg cramps are likely to be related to muscle fatigue and nerve problems. The risk of having night leg cramps increases with age. Pregnant women also have a higher likelihood of having night leg cramps. Several conditions, such as kidney failure and diabetic nerve damage, are known to cause night leg cramps. But if you have one of these, you're most likely aware of it and have symptoms other than night leg cramps.
How they can cause leg cramps: Researchers have known. for more than 20 years that beta-blockers can induce leg. cramps, but they haven't yet determined why. Studies have. shown that beta-blockers cause the arteries in the legs and. arms to narrow, which in turn causes less blood to flow through. the limbs.