Since Medco and Express Scripts have come together as one company to manage your prescription drug benefit, the information Medco had on file for you is now available to the merged company.
Frigid winds make you shiver; dry air chaps unprotected lips and hands; and a lack of sunshine can even cause depression. Cold weather also puts immense strain on the heart. Low temperatures cause your blood vessels and arteries to narrow, restricting blood flow and reducing oxygen to the heart. Your heart must pump harder to circulate blood through the constricted blood vessels. As a result, your blood pressure increases. A sudden spike in blood pressure â especially when paired with outdoor exertion, such as shoveling a snowy sidewalk â can cause serious issues such as: 1  Unstable chest pain.
In mammals, temperature receptors innervate various tissues including the skin (as cutaneous receptors), cornea and urinary bladder. Neurons from the pre-optic and hypothalamic regions of the brain that respond to small changes in temperature have also been described, providing information on core temperature.nother molecular component of cold transduction is the temperature dependence of so-called leak channels which pass an outward current carried by potassium ions. Some leak channels derive from the family of two-pore (2P) domain potassium channels.