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Pulmonary edema facts. 1  Pulmonary edema is typically caused by filling of alveoli in the lungs by fluid leaking out of the blood. 2  Pulmonary edema may be caused by a number of cardiac or non-cardiac conditions.  Breathing difficulty is the main manifestation of pulmonary edema.
These conditions cause excess fluid in the lungs because organs such as the kidneys can no longer remove and balance fluids the way they should or because a disease causes inflammation in the body, states WebMD. Sometimes pleural effusion causes no symptoms.