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From Wikipedia, the free encyclopedia. Pediatric acute-onset neuropsychiatric syndrome (PANS) is a neuropsychiatric syndrome still under research, leading to rapid onset Obsessive-compulsive disorder (OCD) and/or tics in children and adolescents.his portion of the brain is responsible for mediating cognition, emotion, and movement. Research into the etiology of obsessive-compulsive disorder has identified dysfunctions of the basal ganglia as a key factor for the onset of OCD. A similar syndrome in adults is known as Post-inflammatory Brain Syndrome (PIBS).
To accomplish this goal, the PANDAS criteria were modified to describe PANS â Pediatric Acute-onset Neuropsychiatric Syndrome. PANS encompasses the whole group of acute-onset cases of OCD while PANDAS describes those cases of PANS that have a documented association with streptococcal infections.PANS and PANDAS are comparable to cancer and leukemia (respectively) as PANS is the large class of disorders and PANDAS is one specific type.he term is used to describe a subset of children and adolescents who have Obsessive Compulsive Disorder (OCD) and/or tic disorders, and in whom symptoms worsen following strep. infections such as Strep throat and Scarlet Fever. PANS is a newer term used to describe the larger class of acute-onset OCD cases.