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It may be time to talk to your doctor. PREMARIN is a prescription medicine used to treat moderate to severe hot flashes due to menopause. Learn about PREMARINÂ® (conjugated estrogens tablets, USP) for the treatment of moderate to severe hot flashes due to menopause. You, your menopause, and your hot flashes. Keeping track of your hot flashes may be helpful.
Mechanism of Action. Premarin for oral administration contains a mixture of conjugated estrogens obtained exclusively from natural sources, occurring as the sodium salts of water-soluble estrogen sulfates blended to represent the average composition of material derived from pregnant mares' urine.