Top Ten Tips for Graduate Students Who Want to Conduct a Meta-analysis. All you need to conduct a meta-analysis is use of one or more comprehensive literature search engines (e.g., Web of Science, PsycINFO, PubMed), access to a basic statistics program such as SPSS or SAS at your disposal, and a good idea for a meta-analysis topic.
Signs and symptoms vary depending on what parts of your body are affected by Wilson's disease. They may include: 1  Fatigue, lack of appetite or abdominal pain.  Jaundice, a yellowing of the skin and the whites of the eye.
Wilson disease may affect several of the body's systems. Either the liver or the brain can be harmed first, with signs as early as 4 years, or as late as 70 years of age. Symptoms of liver disease include: Jaundice, which is when the skin or the white part of the eye turns yellow.