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Pulmonary edema facts. 1  Pulmonary edema is typically caused by filling of alveoli in the lungs by fluid leaking out of the blood. 2  Pulmonary edema may be caused by a number of cardiac or non-cardiac conditions.  Breathing difficulty is the main manifestation of pulmonary edema.
Conditions that cause fluid in the lungs that are not related to the heart are known as non-cardiac pulmonary edema. In these conditions, the alveoli or capillaries become leaky allowing fluid to accumulate in the lungs. Non-cardiac pulmonary edema is caused by a number of factors, including: 1  Lung infections. Treating fluid in the lungs due to high-altitude. 2  Fluid in the lungs due to high-altitude is also known as high-altitude pulmonary edema (HAPE). 3  If you begin to experience symptoms of HAPE you should descend 600 - 900 feet to lower altitude as soon as possible. 4  In some cases you should take oxygen.