GFR is related inversely and nonlinearly to serum creatinine. Age, gender, and race all affect muscle mass and, in turn, serum creatinine. Both the MDRD Study and CKD-EPI equations include variables to account for serum creatinine variation with age, gender, and race.
When a nerve is stimulated, its cell membrane is depolarised so that the inside of the cell becomes less negative. The potential is conducted along the axon to the axon termin â¦ al.At the dendrite it stimulates the release of a chemical transmitter, which diffuses across a synapse.The transmitter binds to receptor sites on the postsynaptic cell membrane to stimulate the generation of another impulse.+ 4 others found this useful.t the dendrite it stimulates the release of a chemical transmitter, which diffuses across a synapse. The transmitter binds to receptor sites on the postsynaptic cell membrane to stimulate the generation of another impulse. + 4 others found this useful.
An action potential (or impulse, if you like) reaches the presynaptic knob. This causes calcium gates in the membrane to open, and an there is an influx of calcium ions into the axon.this causes vesicles (like little sacks) containing transmitter substance, to move towards, and fuse with, the synaptic membrane. synapse is a junction where two nerves meets. when action potential reaches a synapse, the pores open allowing an afflux of calcium ions into presynaptic terminal.