Scleritis (inflammation of sclera) is a strong indication of the underlying medical problem. It can be due to fungal, viral or parasitic infection, trauma, exposure to chemicals, poisonous gases or due to post-surgical complications.
Mast cells are granulated cells typically found in connective tissue. These cells mediate immune responses to foreign particles. In particular, they release large amounts of histamine and enzymes in response to antigen recognition.
Histamine is secreted by basophils and mast cells as part of a local immune response to the presence of invading bodies. The basophils and mast cells are found in nearby connective tissue.y Dr Ananya Mandal, MD. Histamine is an amine that is produced as part of a local immune response to cause inflammation.