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lip. ( 1 of an embryonic BLASTOPORE) the rim of the blastopore. ( 2 of a flower perianth) a group of perianth segments united to a greater or lesser extent, to form a distinct grouping thus divided from the rest of the perianth. ( 3 of vertebrates) one of two fleshy parts (upper and lower) surrounding the mouth.
Medical Definition of Lip. Lip: One of the two fleshy folds that surround the opening of the mouth. The upper lip is separated from the nose by the philtrum, the area that lies between the base of the nose and the pigmented edge (called the vermillion border or the carmine margin) of the upper lip. The upper and lower lips meet at the corners (angles) of the mouth, which are called the oral commissures.