GFR is related inversely and nonlinearly to serum creatinine. Age, gender, and race all affect muscle mass and, in turn, serum creatinine. Both the MDRD Study and CKD-EPI equations include variables to account for serum creatinine variation with age, gender, and race.
When a nerve is stimulated, its cell membrane is depolarised so that the inside of the cell becomes less negative. The potential is conducted along the axon to the axon termin â¦ al.At the dendrite it stimulates the release of a chemical transmitter, which diffuses across a synapse.The transmitter binds to receptor sites on the postsynaptic cell membrane to stimulate the generation of another impulse.+ 4 others found this useful.t the dendrite it stimulates the release of a chemical transmitter, which diffuses across a synapse. The transmitter binds to receptor sites on the postsynaptic cell membrane to stimulate the generation of another impulse. + 4 others found this useful.
The impulse originates in a receptor at the point of stimulation, passes through an afferent neuron or neurons to a reflex center in the brain or spinal cord, and from the center out through efferent neurons to the effector organ, where the response occurs.. the route followed by nerve impulses in the production of a reflex act, from the peripheral receptor organ through the afferent nerve to the central nervous system synapse and then through the efferent nerve to the effector organ.