1 Management of chronic, intractable, non-terminal pain that are not responsive to other modalities; 2  Treatment of cancer pain in those patients who have short life expectancy (less than a year); and.  Alternative management to treat spasticity in order to improve balance, gait, self-care, and global rehabilitation.
Diagnosing modic changes. 1  In Modic type 1 there is vascular development in the vertebral body, with findings of inflammation and edema, but no trabecular damage or marrow changes. 2  In Modic type 2 there are changes in bone marrow, with fatty replacement of formerly red, cellular marrow normally seen there.
Many factors can change ECF and ICF volumes. Because water moves freely between compartments, however, the osmolarities of all body fluids are equal. Increasing the ECF solute content (mainly sodium chloride) causes osmotic and volume changes in the ICF â generally, a shift of water out of cells.