1 The processing time does not apply to services where prior approval has to be obtained from authorities in India or elsewhere. For such cases, the processing time is a minimum of thirty (30) business days.  The Consular Officer can at any time call an applicant for a personal interview.
The simian crease is one of the listed signs in Down Syndrome which would imply there's some genetic factor at play. My eldest daughter has a simian crease on one hand and the other hand is 'normal'.
Renal Disorders. 180 Copyright Â© 2004 The Regents of the University of California B. Intrinsic Renal Failure: The most common cause is acute tubular necrosis (ATN) resulting in renal tubular dysfunction. ATN may be precipitated by shock, prolonged prerenal state, or nephrotoxic drugs.