A written agreement which explicitly states a fixed duration that the contract will be in effect. The signing parties are obligated to adhere to the terms and conditions within the contract until the expiration, or end date, of the contract. http://www.businessdictionary.com/definition/term-contract.html.
The most common symptoms of Lou Gehrig's Disease are: 1  twitching. 2  cramping, or stiffness of muscles. 3  muscle weakness affecting an arm or a leg.  slurred and nasal 1  speech. or difficulty chewing or swallowing.
Basics of ALS (Lou Gehrig's Disease) Signs & Symptoms of ALS. Lou Gehrig's Disease Symptoms. Once a motor neuron degenerates completely, the muscle that it controls no longer receives impulses from the brain. Approximately 60 percent of ALS patients experience muscle weakness and stiffness as the initial symptom. Usually the first muscles affected are those in the arms and legs.