1 Coadministration with moderate CYP3A4 and/or PgP inhibitors: Reduce dose by 50%; administer every other day if dose reduction is required for patients receiving the lowest available strength and maintain trough concentrations of 5 to 15 ng/mL.
A pregnant mouse can give birth to six to 12 babies in one litter. A female mouse can become pregnant several times a year. One mouse couple can produce 40 or more babies in one year.
According to a University of Michigan resource on breeding mice for laboratory purposes, a female mouse can give birth to between four and eight litters each year. Each litter consists of an average of between six to eight mice. A female mouse reaches sexual maturity at between 6 and 8 weeks old. The gestation period for a litter typically lasts between 19 and 21 days. Mice are very common in laboratory research, especially in genetics, in part because of this quick generation time, but this quality also makes them a pervasive pest animal.