1 Coadministration with moderate CYP3A4 and/or PgP inhibitors: Reduce dose by 50%; administer every other day if dose reduction is required for patients receiving the lowest available strength and maintain trough concentrations of 5 to 15 ng/mL.
A pregnant mouse can give birth to six to 12 babies in one litter. A female mouse can become pregnant several times a year. One mouse couple can produce 40 or more babies in one year.
Mice *can* get pregnant as early as 4 weeks. However, it is unbelievably hard on them if they do. Never breed your mouse that young, no matter what. In addition, make sure you separate your babies (males from females) at 4 weeks of age so this doesn't happen. It is generally recommended to wait until the female is 12 weeks old or older before she is bred for her first litter. Breeding sooner is bad for the mother and the babies.