1 The processing time does not apply to services where prior approval has to be obtained from authorities in India or elsewhere. For such cases, the processing time is a minimum of thirty (30) business days.  The Consular Officer can at any time call an applicant for a personal interview.
The simian crease is one of the listed signs in Down Syndrome which would imply there's some genetic factor at play. My eldest daughter has a simian crease on one hand and the other hand is 'normal'.
A simian crease is a single line that runs across the palm of the hand. People usually have 3 creases in their palms. The term simian crease is not used much anymore, since it tends to have a negative meaning (the word simian refers to a monkey or ape). The crease is usually just referred to as a single palmar crease. Single palmar crease; Transverse palmar crease; Palmar crease.