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Pulmonary edema facts. 1  Pulmonary edema is typically caused by filling of alveoli in the lungs by fluid leaking out of the blood. 2  Pulmonary edema may be caused by a number of cardiac or non-cardiac conditions.  Breathing difficulty is the main manifestation of pulmonary edema.
Pulmonary Edema. Pulmonary edema is characterized by the excessive build up of fluid in the air sacks (alveoli) of the lungs. This can be a result of heart failure, of certain medications, of severe infection or of trauma. In some cases high altitudes can also cause pulmonary edema.