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Pulmonary edema facts. 1  Pulmonary edema is typically caused by filling of alveoli in the lungs by fluid leaking out of the blood. 2  Pulmonary edema may be caused by a number of cardiac or non-cardiac conditions.  Breathing difficulty is the main manifestation of pulmonary edema.
Fluid may collect in the area around the lungs. One common cause of fluid around the lungs is a lung infection, which may be a complication of certain types of surgery or an illness such as pneumonia. During surgery, tubes can be placed in the pleural space to drain fluid and help the lungs heal.