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The organ system in which the blood is pumped through the heart and circulates throughout the body through the blood vessels. Supplement. The cardiovascular system is a closed circulatory system seen in humans and other vertebrates. Its components include the heart, blood vessels, and blood.
The cardiovascular system (see Biology of the Heart) includes the heart (cardio) and blood vessels (vascular). The cardiovascular system is responsible for pumping and circulating the blood.