Atherosclerosis (also known as arteriosclerotic vascular disease or ASVD) is a specific form of arteriosclerosis in which an artery-wall thickens as a result of invasion and accumulation of white blood cells (WBCs) (foam cell) and proliferation of intimal-smooth-muscle cell creating a fibrofatty plaque.
3D Structure of Antimicrobial Peptides 1. Structure annotation The information on the three-dimensional (3D) structure of antimicrobial peptides is annotated in this database from the first version of the APD (Wang & Wang, 2004).It includes methods for structural determination, structural class, structural regions, critical residues, and the type of membrane-mimetic environments.. Structural statistics of antimicrobial peptides A list of antimicrobial peptdes with a defined 3D structure can be obtained by searching the APD database. The statistics of a variety of structures is also provided in this database. Go to the Statistic Interface.
There are several types of antimicrobial drugs that function by disrupting or injuring the plasma membrane. One example is daptomycin, a lipopeptide which has a distinct mechanism of action, disrupting multiple aspects of bacterial cell membrane function.