1 The processing time does not apply to services where prior approval has to be obtained from authorities in India or elsewhere. For such cases, the processing time is a minimum of thirty (30) business days.  The Consular Officer can at any time call an applicant for a personal interview.
Causes of Simian crease that are rare The offical US government definition of a rare disease is one that affects 200,000 people or less. The following causes of Simian crease appear in the population at a rate of less than 200,000 people per year in the USA: Coffin-Lowry syndrome - simian crease.
It can be reduced (short) in horizontal size by fetal alcohol syndrome and in Williams syndrome. The chromosomal conditions trisomy 9 and trisomy 21 (Down syndrome) can cause the palpebral fissures to be upslanted, while Marfan syndrome can cause a downslant. The fissure may be increased in vertical height in Graves' disease, which is manifested as Dalrymple's sign.