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The organ system in which the blood is pumped through the heart and circulates throughout the body through the blood vessels. Supplement. The cardiovascular system is a closed circulatory system seen in humans and other vertebrates. Its components include the heart, blood vessels, and blood.
Heart disease or Cardiovascular disease is an abnormal function of the heart or blood vessels. It can cause an increase in risk for heart attack, heart failure, sudden death, stroke and cardiac rhythm problems, thus resulting in decreased quality of life and decreased life expectancy. The causes of cardiovascular disease range from structural defects, to infection, inflammation, environment and genetics.