Sekine K, Kawashima T and Hashimoto Y. Comparison of the TNF-a Levels Induced by Human-Derived Bifidobacterium longum and Rat-Derived Bifidobacterium animalis in Mouse Peritoneal Cells. Bifidobacteria Microflora 1994;13(2):79-89.
A Sharecare Ad Target User , Administration, answered. An outbreak of oral herpes, or cold sores, should go away on its own in about one or two weeks. Antiviral medications can help them heal faster if taken early. Talk to your doctor if your cold sores do not go away after two weeks. Helpful? 1 person found this helpful.
For pain, you can apply ice to the area or take over-the-counter pain medications such as acetaminophen or ibuprofen. Take 4 500mg Lysine at first sign of a cold sore. Take 1 each morning and 1 each evening for a few days and if caught early enough it will not progress but go away completely.