Scleritis (inflammation of sclera) is a strong indication of the underlying medical problem. It can be due to fungal, viral or parasitic infection, trauma, exposure to chemicals, poisonous gases or due to post-surgical complications.
Mast cells are granulated cells typically found in connective tissue. These cells mediate immune responses to foreign particles. In particular, they release large amounts of histamine and enzymes in response to antigen recognition.
Most tissue histamine is found in granules in mast cells or basophils and its release is immunologic in function. Mast cells are especially numerous at sites of potential injury such as the nose, mouth, and feet, internal body surfaces and blood vessels.Basophils represent only 1% of circulating leukocytes.istamine. Histamines use in the body is not soley involved in allergic inflammatory response. The hormone/chemical transmitter histamine is a biogenic monoamine similar to serotonin, epinephrine and norepinephrine. Chemically histamine is 2-(4-imidazolyl)ethylamine and has the formula C5H9N3.