GFR is related inversely and nonlinearly to serum creatinine. Age, gender, and race all affect muscle mass and, in turn, serum creatinine. Both the MDRD Study and CKD-EPI equations include variables to account for serum creatinine variation with age, gender, and race.
When a nerve is stimulated, its cell membrane is depolarised so that the inside of the cell becomes less negative. The potential is conducted along the axon to the axon termin â¦ al.At the dendrite it stimulates the release of a chemical transmitter, which diffuses across a synapse.The transmitter binds to receptor sites on the postsynaptic cell membrane to stimulate the generation of another impulse.+ 4 others found this useful.t the dendrite it stimulates the release of a chemical transmitter, which diffuses across a synapse. The transmitter binds to receptor sites on the postsynaptic cell membrane to stimulate the generation of another impulse. + 4 others found this useful.
The sequence of events at a synapse is as follows : 1) A nerve impulse reaches the axon terminal of a presynaptic neuron; the membrane is depolarised by an action potential. 2) Depolarisation of the axon terminal during the action potential causes voltage sensitive calcium ion channels to open in the terminal knob.) Synaptic Cleft: This is the narrow gap between the axon terminal of the presynaptic neuron, and the post-synaptic membrane of another excitable cell. It is filled with extracellular fluid. 3) Postsynaptic membrane: The membrane across the synaptic cleft is called the postsynaptic membrane.