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Denis transfused the blood from a sheep to a 15-year old boy and later to a labourer, both of whom survived the transfusions. In 1818, British obstetrician James Blundell successfully transfused human blood to a patient who had hemorrhaged during childbirth. In 1901, Karl Landsteiner, an Austrian physician discovered the first human blood groups, which helped transfusion to become a safer practice.
HIV infection resulting from blood transfusion has been documented repeatedly since the first case report in late 1982.(6-8,9) In the United States, almost all cases are due to blood transfused before March 1985, when HIV antibody testing became available to screen donated blood.IV-1 antibody ELISA tests detect 8-92% of HIV-2 infections, depending on the geographic source of sera and the test used. As of 1998, screening has identified four blood or plasma donors with HIV-2 infection.(31,34).