For example, your standard fixed overhead cost is $3 per unit. If your actual fixed overhead cost is $4 per unit, you have an unfavorable variance of $1. You spent $1 more per unit than you had originally budgeted.
In biology, histones are highly alkaline proteins found in eukaryotic cell nuclei that package and order the DNA into structural units called nucleosomes. They are the chief protein components of chromatin, acting as spools around which DNA winds, and playing a role in gene regulation. Without histones, the unwound DNA in chromosomes would be very long (a length to width ratio of more than 10 million to 1 in human DNA).
Best Answer: A chromosome is an organized structure of DNA and protein (Chromatin) that is found in cells. Chromosomes contain DNA-bound proteins, which serve to package the DNA and control its functions. The essential unit of DNA packaging is the nucleosome. A nucleosome consists of a small amount of DNA wrapped up with protein. The proteins that interact with DNA to form chromatin comprise a family of basic proteins called histones. There are five different types of histone protein: H1, H2A, H2B, H3, and H4. Of these, two molecules each of H2A, H2B, H3, and H4 combine to form a histone octamer. DNA wraps around the octamer, making 1 3/4 turns around the protein complex. The octamer plus the DNA comprise what is called the nucleosome core. A small stretch of DNA runs between adjacent nucleosome cores, and is known as the linker. A single nucleosome consists of one core plus a linker.