Top Ten Tips for Graduate Students Who Want to Conduct a Meta-analysis. All you need to conduct a meta-analysis is use of one or more comprehensive literature search engines (e.g., Web of Science, PsycINFO, PubMed), access to a basic statistics program such as SPSS or SAS at your disposal, and a good idea for a meta-analysis topic.
Signs and symptoms vary depending on what parts of your body are affected by Wilson's disease. They may include: 1  Fatigue, lack of appetite or abdominal pain.  Jaundice, a yellowing of the skin and the whites of the eye.
Wilson disease is sometimes difficult to diagnose. Affected individuals may have no symptoms for years. When symptoms develop, they can be subtle. Sometimes symptoms of Wilson disease resemble hepatitis. Alternatively, some individuals have an enlarged liver and spleen and liver test abnormalities.