Top Ten Tips for Graduate Students Who Want to Conduct a Meta-analysis. All you need to conduct a meta-analysis is use of one or more comprehensive literature search engines (e.g., Web of Science, PsycINFO, PubMed), access to a basic statistics program such as SPSS or SAS at your disposal, and a good idea for a meta-analysis topic.
Signs and symptoms vary depending on what parts of your body are affected by Wilson's disease. They may include: 1  Fatigue, lack of appetite or abdominal pain.  Jaundice, a yellowing of the skin and the whites of the eye.
Wilson's disease or hepatolenticular degeneration is an autosomal recessive genetic disorder in which copper accumulates in tissues; this manifests as neurological or psychiatric symptoms and liver disease.he condition is due to mutations in the Wilson disease protein (ATP7B) gene. A single abnormal copy of the gene is present in 1 in 100 people, who do not develop any symptoms (they are carriers).