The adrenal medulla develops from neural tissue and secretes two hormones, epinephrine and norepinephrine. These two hormones are secreted in response to stimulation by sympathetic nerve, particularly during stressful situations. A lack of hormones from the adrenal medulla produces no significant effects.
Premature ventricular contractions (PVCs, PVC) are premature heartbeats originating from the ventricles of the heart. Premature ventricular contractions are premature because they occur before the regular heartbeat. The heart has four chambers. The upper two chambers are the atria, and the lower two chambers are the ventricles.
Clinical Significance of Premature Atrial Complex (PAC) 1  PACs are a normal electrophysiological phenomenon not usually requiring investigation or treatment. 2  Frequent PACs may cause palpitations and a sense of the heart âskipping a beatâ. In patients with underlying predispositions (e.g. left atrial enlargement, ischaemic heart disease, WPW), a PAC may be the trigger for the onset of a re-entrant tachydysrhythmia â e.g. AF, flutter, AVNRT, AVRT.