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The opposite is hypothyroidism, when the thyroid gland does not make enough thyroid hormone. Graves' disease is the cause of about 50% to 80% of case of hyperthyroidism in the United States. Other causes include multinodular goiter, toxic adenoma, inflammation of the thyroid, eating too much iodine, and too much synthetic thyroid hormone. A less common cause is a pituitary adenoma.
A bacterial or viral infection can make your thyroid gland swell. This is called thyroiditis. The damaged thyroid leaks its hormone into your blood, which causes your thyroid hormone level to rise for a short time. Once that hormone is used up, your thyroid hormone levels will drop. Low levels from thyroiditis often don't last long, because the gland hasn't been permanently damaged.