There may be a loss of bowel and bladder function as the nervous system shuts down. The caregiver - usually a nurse or hospice caretaker - may suggest a catheter to collect urine; you can also place absorbent pads on the bed in case of accidents.
Fibroblasts begin entering the wound site two to five days after wounding as the inflammatory phase is ending, and their numbers peak at one to two weeks post-wounding. By the end of the first week, fibroblasts are the main cells in the wound. Fibroplasia ends two to four weeks after wounding.
The period during which infected people are able to spread the disease is believed to start one or two days before the rash breaks out and to continue until all the blisters have formed scabs, which usually happens four to seven days after the rash breaks out but may be longer in adolescents and adults.