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Depression and anxiety may also cause you to eat more and exercise less than normal. Metabolic or hormonal disruptions, such as hypothyroidism or polycystic ovary syndrome, can cause sudden weight gain and bloating. Cushing's disease can also cause rapid weight gain, especially in the upper body.
In some cases though, rapid abdominal weight gain can actually be a sign of an underlying medical condition. While hormonal disorders can be culprits, other conditions including liver disease and ovarian tumors may cause abdominal bloating and weight gain as well.D rendering of the human liver. Photo Credit satellitesixty/iStock/Getty Images. End-stage liver disease, or liver failure, can also cause rapid, abdominal weight gain. Liver failure may be due to a number of conditions including hepatitis and alcohol abuse.