1 Management of chronic, intractable, non-terminal pain that are not responsive to other modalities; 2  Treatment of cancer pain in those patients who have short life expectancy (less than a year); and.  Alternative management to treat spasticity in order to improve balance, gait, self-care, and global rehabilitation.
Diagnosing modic changes. 1  In Modic type 1 there is vascular development in the vertebral body, with findings of inflammation and edema, but no trabecular damage or marrow changes. 2  In Modic type 2 there are changes in bone marrow, with fatty replacement of formerly red, cellular marrow normally seen there.
When osmotic pressure changes, osmoreceptors expand and contract in response. When there are low levels of solutes in the blood, these sensory receptors swell, because water moves from the blood into the cells. When the blood has a high concentration of solutes, water moves out of the osmoreceptors and into the blood.