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A nucleated red blood cell, or NRBC, is a red blood cell (RBC) that retains nucleus. Normally, NRBCs are only found in the circulation of fetuses and newborn infants. nucleated red blood cell, or NRBC, is a red blood cell (RBC) that retains nucleus. Normally, NRBCs are only found in the circulation of fetuses and newborn infants.
Advertisement. Red blood cells are referred to as erythrocytes in medical terms. These blood cells make up the major chunk of blood that helps carry oxygen and nutrients to each and every cell, tissue, organ, and part of the body through the circulatory system.Under normal circumstances, RBCs appear as flexible, biconcave disks.hese nucleated RBCs (NRBCs) are present in the peripheral blood of newborns up to 5 days after their birth. However, the appearance of nucleated red blood cells in adults as well as children indicates there may be damage to the bone marrow, stress, or presence of a serious underlying disease.