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Compared to other drugs in its class, fluoxetine generally causes less severe withdrawal symptoms due to its long half-life. Here are some things that might happen if you quit taking it cold turkey: Neurological: The emotional and mental effects of fluoxetine withdrawal are often among the most troubling.ere are some things that might happen if you quit taking it cold turkey: Neurological: The emotional and mental effects of fluoxetine withdrawal are often among the most troubling.
Prozac, due its extremely long elimination half life, is one of the milder and less prone SSRIs in that regard.A study on fluoxetine discontinuation in 395 patients on 20mg/day showed only a small percentage reported mild vertigo following abrupt withdrawal of the drug. So, you are probably fine to quit it cold turkey.