1 Coadministration with moderate CYP3A4 and/or PgP inhibitors: Reduce dose by 50%; administer every other day if dose reduction is required for patients receiving the lowest available strength and maintain trough concentrations of 5 to 15 ng/mL.
A pregnant mouse can give birth to six to 12 babies in one litter. A female mouse can become pregnant several times a year. One mouse couple can produce 40 or more babies in one year.
This plug stays in place for some 24 hours. The gestation period is about 19â21 days, and they give birth to a litter of 3â14 young (average six to eight). One female can have 5 to 10 litters per year, so the mouse population can increase very quickly. Breeding occurs throughout the year.his plug stays in place for some 24 hours. The gestation period is about 19â21 days, and they give birth to a litter of 3â14 young (average six to eight). One female can have 5 to 10 litters per year, so the mouse population can increase very quickly. Breeding occurs throughout the year.