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A Sharecare Ad Target User , Administration, answered. An outbreak of oral herpes, or cold sores, should go away on its own in about one or two weeks. Antiviral medications can help them heal faster if taken early. Talk to your doctor if your cold sores do not go away after two weeks. Helpful? 1 person found this helpful.
To get rid of a cold sore fast, try one of the over-the-counter medications, home remedies, or prescription medications commonly used against cold sores. These may include options like antiviral creams, vanilla extract, and petroleum jelly.