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Denis transfused the blood from a sheep to a 15-year old boy and later to a labourer, both of whom survived the transfusions. In 1818, British obstetrician James Blundell successfully transfused human blood to a patient who had hemorrhaged during childbirth. In 1901, Karl Landsteiner, an Austrian physician discovered the first human blood groups, which helped transfusion to become a safer practice.
1990 - The first specific test for hepatitis C was introduced. This major cause of non-A, non-B hepatitis. (the hepatitis C virus, HCV, has, as of the date of this writing, not been isolated) 1992 - Testing of donor Blood for HIV-1 and HIV-2 antibodies (anti-HIV-1 and anti-HIV-2) was implemented.492 - Pope Innocent VIII, in Rome, had an apoplectic stroke; became weak and went into a coma. His physician advised a Blood transfusion as a therapeutic measure for the Pope's illness. Employing crude methods, the Pope did not benefit and died by the end of that year.