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Lactoferrin is related to another stool test, calprotectin. Both are substances that are released by WBCs in the stool and are associated with intestinal inflammation. The clinical use of these tests is still relatively new.n endoscopy (colonoscopy or sigmoidoscopy) may be indicated as a follow-up test. Increases in lactoferrin are seen with IBD but also with other inflammatory conditions, with intestinal bacterial infections, some parasitic infections, and with colon cancer.
A Closer Look At Lactoferrin. First isolated from human milk in 1960, lactoferrin (at right), also known as lactotransferrin, is an important member of raw bovine (cow's) milk's self-defense system.actoferrin's anti-fungal/ anti-bacterial properties lie in its competitiveness for iron as well. Candida albicans, responsible for yeast infections if it gets out of hand, doesn't do well in an iron-poor environment. Neither do numerous strains of pathogenic bacteria, such as E. coli, mentioned above.