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A Sharecare Ad Target User , Administration, answered. An outbreak of oral herpes, or cold sores, should go away on its own in about one or two weeks. Antiviral medications can help them heal faster if taken early. Talk to your doctor if your cold sores do not go away after two weeks. Helpful? 1 person found this helpful.
There are many things you can do to make cold sores disappear. You can buy Abreva. It is kind of pricey, but it actually works. Even try Cold Sore Treatment, because it heals â¦pretty quick and it takes about 2 days or less. Abreva and cold sore treatment work equally. If you wouldn't like to buy anything to heal your blister, then get a cup and put warm water, then a spoon of salt and mix them until the salt dissolves.