1 Management of chronic, intractable, non-terminal pain that are not responsive to other modalities; 2  Treatment of cancer pain in those patients who have short life expectancy (less than a year); and.  Alternative management to treat spasticity in order to improve balance, gait, self-care, and global rehabilitation.
Diagnosing modic changes. 1  In Modic type 1 there is vascular development in the vertebral body, with findings of inflammation and edema, but no trabecular damage or marrow changes. 2  In Modic type 2 there are changes in bone marrow, with fatty replacement of formerly red, cellular marrow normally seen there.
Minimal clinicall important change (MCIC) is defined as the minimal change in the score that is meaningful for patients [1â12]. Different approaches can be used to determine MCIC. One is to estimate the mean change in score in patients who actually report to have improved (referred to as mean change score, or MCS).