Reg. 259 (Jan. 4, 2011). 4 See definition of applicable clinical trial at 42 U.S.C. 282(j)(1)(A). The content of this article is intended to provide a general guide to the subject matter. Specialist advice should be sought about your specific circumstances.
We identified a risk haplotype in SLC18A2 and found a consistent result in the Detroit Neighborhood Health Study (DNHS) (N=748), an epidemiologic sample of primarily African-American adults residing in urban Detroit (Goldmann et al, 2011).
Polymorphisms in the MTHFR gene have also been studied as possible risk factors for a variety of common conditions. These include heart disease, stroke, high blood pressure (hypertension), high blood pressure during pregnancy (preeclampsia), an eye disorder called glaucoma, psychiatric disorders, and certain types of cancer.