In people with kidney disease, betaine may interfere with drugs taken to lower cholesterol levels in the blood. Supporting Research. ... Br J Nutr. 2004;92:665-669. Atkinson W, Elmslie J, Lever M, Chambers ST, George PM. ...
Apraxia is a motor disorder caused by damage to the brain (specifically the posterior parietal cortex), in which the individual has difficulty with the motor planning to perform tasks or movements when asked, provided that the request or command is understood and he/she is willing to perform the task.
Aprataxin removes AMP from DNA ends following abortive ligation attempts by DNA Ligase IV during non-homologous end joining, thereby permitting subsequent attempts at ligation. DNA strand breaks. Ataxia oculomotor apraxia-1 is a neurological disorder caused by mutations in the APTX gene that encodes aprataxin. The neurological disorder appears to be caused by the gradual accumulation of unrepaired DNA strand breaks resulting from abortive DNA ligation events.