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In brief: Naproxen. In a patient with normal kidney and liver function, Naproxen would normally be completely out of the body within 5 - 7 days. In brief: Naproxen. In a patient with normal kidney and liver function, Naproxen would normally be completely out of the body within 5 - 7 days.  In brief: Naproxen.
Stop taking nonprescription naproxen and call your doctor if your symptoms get worse, you develop new or unexpected symptoms, the part of your body that was painful becomes red or swollen, your pain lasts for more than 10 days, or your fever lasts for more than 3 days.