Recent reports have identified EPCAM deletions in patients with Lynch syndrome. As the data about EPCAM and LS is rapidly changing, consider consulting with a genetics specialist. â¢ If no mutation is found, follow up with MSH6 genetic testing. If only MSH6 is absent â¢ If only MSH6 is absent, the patient may have LS.
Progesterone is one of the dominant sex hormones in females, and it helps maintain a pregnancy by preventing the contraction of the uterus or womb. Progesterone can lead to constipation by slowing the passage of digested food through the intestines.
1 Nasal septal deviations can also cause sinus problems and may contribute to chronic infections. 2  Diagnosing a deviated septum involves a thorough physical examination, nasal endoscopy and a CT scan. 3  Nasal steroids sprays can be used for problems associated with nasal septal deviations and turbinate hypertrophy.