Efficacy is diminished and risk of ototoxicity increased in patients with hypoproteinemia (associated with nephrotic syndrome); ototoxicity is associated with rapid injection, severe renal impairment, use of higher than recommended doses, concomitant therapy with aminoglycoside antibiotics, ethacrynic acid, or other ototoxic drugs.
www.phac-aspc.gc.ca. The Public Health Agency of Canada (French: Agence de la santÃ© publique du Canada) is an agency of the Government of Canada that is responsible for public health, emergency preparedness, and response and infectious and chronic disease control and prevention.
Health Canada's Role. We work with governments, industry and consumers to establish policies, regulations and standards related to the safety and nutritional quality of all food sold in Canada.Health Canada is responsible for assessing the Canadian Food Inspection Agency's activities related to food safety.The Department also evaluates the safety of veterinary drugs used in food-producing animals.ealth Canada's Role. We work with governments, industry and consumers to establish policies, regulations and standards related to the safety and nutritional quality of all food sold in Canada.