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Calcium: Because of the nearly proving migraine prevention power of magnesium, migraine supplements will also often contain calcium, which is necessary for the effective use of magnesium. 3. Vitamin B2: The ability to calm the brain down is the secret to this potential migraine reducer.itamin B6: Responsible for helping to produce dopamine, serotonin and histamine, healthy levels of B6 are important to reduce allergy triggered migraines. 7. Vitamin B9: B9 is used to treat depression, inflammation and headaches and is showing promise as a potential prevention supplement. 8.
Further studies are needed to elucidate whether vitamin supplementation is effective in migraine patients in general, and whether patients with mild deficiency are more likely to benefit from supplementation, said lead study author Dr. Suzanne Hagler in a Cincinnati Children's Hospital Medical Center news release.