Efficacy is diminished and risk of ototoxicity increased in patients with hypoproteinemia (associated with nephrotic syndrome); ototoxicity is associated with rapid injection, severe renal impairment, use of higher than recommended doses, concomitant therapy with aminoglycoside antibiotics, ethacrynic acid, or other ototoxic drugs.
www.phac-aspc.gc.ca. The Public Health Agency of Canada (French: Agence de la santÃ© publique du Canada) is an agency of the Government of Canada that is responsible for public health, emergency preparedness, and response and infectious and chronic disease control and prevention.
1 The Canadian Food Inspection Agency, guided by the Government's Safe Food for Canadians Action Plan, verifies that industry is meeting federal food safety and regulatory requirements, and sets standards to detect and prevent risks to Canada's food supply.he Government of Canada communicates safe food handling information through the Healthy Canadians website, through public notices, food recall warnings, social media and investments to promote healthy living, including healthy eating.