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Inositol trisphosphate or inositol 1,4,5-trisphosphate (also commonly known as triphosphoinositol; abbreviated InsP3 or Ins3P or IP3), together with diacylglycerol (DAG), is a secondary messenger molecule used in signal transduction and lipid signaling in biological cells.
My laboratory researches IP3 receptors. The answers to the obvious questions of what IP3 receptors are and what they do are summarized in Figures 1 and 2.s you can see in the movie (fig. 1), when IP3 (red) binds to the IP3 receptor tetramer (green), the pore opens and Ca2+ stored in the ER flows down its concentration gradient into the cytosol. This 'mobilized' Ca2+ then triggers many cell functions, ranging from secretion to gene expression.