Medical uses. Both positive and negative inotropes are used in the management of various cardiovascular conditions. The choice of agent depends largely on specific pharmacological effects of individual agents with respect to the condition. One of the most important factors affecting inotropic state is the level of calcium in the cytoplasm of the muscle cell.
The American flag has been around for over two hundred years. The first flag to be used by Washington was on New year's Day, 1776 when he ordered the Grand Union flag to be hoisted above his place on Prospect Hill during the siege over the British Army in Boston.It had thirteen alternating red and white stripes with the British Union Jack in the upper left hand corner.This was the start of many US flags to be hoisted as the American Flag. Soon after that in May, Betsy Ross claimed to have sewn the first US flag.oday our flag has thirteen stripes representing the original thirteen colonies with seven red stripes and six white. It has 50 stars representing all of our states on the blue background in the upper left hand corner. The American Flag can be seen in just about every person's home or belongings in this country.
The 1818 Flag :Realizing that the addition of a new star and new stripe for each new State was impractical, Congress passed the Flag Act of 1818 which returned the flag design to 13 stripes and specified 20 stars for the 20 states. This Flag became the Official United States Flag on April 13th, 1818.