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How long does lisinopril 10mg ACE Inhibitor stay in your system?   Answer   Answer The plasma half-life of lisinopril is approximately 12 hours. This means that in the average person, lisinopril should disappear from the body withâ¦in 3-4 days.
My experience with the generic lisinopril as a 32 year-old male with an extensive family history of cardiovascular disease (cardiomyopathy) - Began at 20mg twice a day with some improvement; a few months after initial treatment PCP prescribed 40mg twice a day; I did not experience any side effects that I recall.