Morning stiffness is often an early sign of arthritis. Stiffness that lasts for a few minutes is usually a symptom of a degenerative form of arthritis. Stiffness that lasts for several hours is generally a symptom of inflammatory arthritis and is typical of RA.
Early cities developed in a number of regions, from Mesopotamia to Asia to the Americas. The very first cities were founded in Mesopotamia after the Neolithic Revolution, around 7500 BCE. Mesopotamian cities included Eridu, Uruk, and Ur. Early cities also arose in the Indus Valley and ancient China.
With the increased commerce of the canal, the population boomed and Buffalo was incorporated as a city in 1832. On 1 June 1843, the world's first steam-powered grain elevator was put into service by a local merchant, Joseph Dart, Jr., and an engineer, Robert Dunbar.