With approximately 450,000 active CPAs in the United States, the CPA certification is the most popular professional designation for accountants. Earning the CPA designation is no easy feat, as the CPA exam is known for its extreme difficulty.
Toxicokinetics (often abbreviated as 'TK') is the description of both what rate a chemical will enter the body and what occurs to excrete and metabolize the compound once it is in the body. It is an application of pharmacokinetics to determine the relationship between the systemic exposure of a compound in experimental animals and its toxicity.
A central concept of toxicology is that the effects of a toxin are dose-dependent; even water can lead to water intoxication when taken in too high a dose, whereas for even a very toxic substance such as snake venom there is a dose below which there is no detectable toxic effect.