1 0.3-5 mg at bedtime is a typical dose. 2  In children with insomnia due to delayed sleep onset, melatonin 5 mg at 6:00 PM daily. 3  In children with developmental disorders (including cerebral palsy, autism, and intellectual disabilities), melatonin 5 mg at 8:00 PM daily.
Cocaine is a weakly alkaline compound (an  alkaloid ), and can therefore combine with acidic compounds to form various salts. The hydrochloride (HCl) salt of cocaine is by far the most commonly encountered, although the sulfate (-SO 4) and the nitrate (-NO 3) are occasionally seen.t is commonly snorted, inhaled, or injected into the veins. Mental effects may include loss of contact with reality, an intense feeling of happiness, or agitation. Physical symptoms may include a fast heart rate, sweating, and large pupils.
For particularly lipophilic drugs, this helps it dissolve in water, as the compound will dissociate into its constituent ammonium and chloride ions. One such example would be cocaine - in powder form, it is a hydrochloride salt. When you deprotonate the amine, you get the free base form, also known as crack cocaine.