Antonie van Leeuwenhoek: Antonie van Leeuwenhoek, Dutch microscopist who was the first to observe bacteria and protozoa. His researches on lower animals refuted the doctrine of spontaneous
1 Rub the dripping or butter over the joint. 2  Season generously with salt and pepper. 3  Roast the beef topside according to your desired temperature: 20 minutes per 500g, plus an additional 20 minutes for rare; 25 minutes per 500g, plus 25 minutes for medium; 30 minutes per 500g, plus 30 minutes for well done. Roast the beef topside according to your desired temperature: 20 minutes per 500g, plus an additional 20 minutes for rare; 25 minutes per 500g, plus 25 minutes for medium; 30 minutes per 500g, plus 30 minutes for well done.
The USDA recommends cooking to medium, but this lean, tougher cut turns out better at medium-rare. A boneless beef cut like a top round roast typically takes 30 to 35 minutes per pound to reach the USDA-recommended temperature of 145 degrees Fahrenheit when roasted at 350 F, a total of 120 to 140 minutes.