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Familial Periodic Paralysis. Familial periodic paralysis is a rare autosomal dominant condition with considerable variation in penetrance characterized by episodes of flaccid paralysis with loss of deep tendon reflexes and failure of muscle to respond to electrical stimulation.
Autosomal dominant inheritance means that the gene in question is located on one of the autosomes. These are numbered pairs of chromosomes, 1 through 22. (These chromosomes do not determine an offspring's gender.) Dominant means that only one gene from one parent is necessary to pass down a trait or a disorder. When a parent has a dominant trait or disorder, there is a 50 percent chance that any child he or she has will also inherit the trait or disorder: