Morning stiffness is often an early sign of arthritis. Stiffness that lasts for a few minutes is usually a symptom of a degenerative form of arthritis. Stiffness that lasts for several hours is generally a symptom of inflammatory arthritis and is typical of RA.
Early cities developed in a number of regions, from Mesopotamia to Asia to the Americas. The very first cities were founded in Mesopotamia after the Neolithic Revolution, around 7500 BCE. Mesopotamian cities included Eridu, Uruk, and Ur. Early cities also arose in the Indus Valley and ancient China.
When the United States first became a country in 1776, Philadelphia was its most populous city. By the time the first U.S. census count was completed in 1790, New York City had already grown to be 14% more populous than Philadelphia (though Philadelphia still had the larger metropolitan population in 1790).