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In brief: Naproxen. In a patient with normal kidney and liver function, Naproxen would normally be completely out of the body within 5 - 7 days. In brief: Naproxen. In a patient with normal kidney and liver function, Naproxen would normally be completely out of the body within 5 - 7 days.  In brief: Naproxen.
You should not take over-the-counter (OTC) naproxen for more than 10 days without consulting your healthcare provider. Naproxen Dosage for Mild-to-Moderate Pain The recommended starting prescription-strength dose for most people with mild-to-moderate pain or painful menstruation is one of the following: Naproxen Dosage for Mild-to-Moderate Pain.