Strain-specifictransgene methylation occurs early in mouse developmentand can be recapitulated in embryonic stem cells. Develop-ment 121: 2853â2859.Wigler, M., Levy, D., and Perucho, M. 1981. The somatic repli-cation of DNA methylation. Cell 24: 33â40.Wolffe, A.P., Jones, P.L., and Wade, P.A. 1999.
1 Toronto remains a mosaic of many languages. In 2006, forty-seven percent of the population had a mother tongue in a language other than English or French. 2  The top 5 mother tongue languages in 2006 were:  Chinese (420,000);
Today, English is far and away the most prominent language spoken in Canada, the first language for nearly 60 percent of the population. Even in those provinces where the French language is most commonly heard, a majority of the residents can speak at least some English, and nearly half are bilingual, meaning they are fluent in both French and English.