the interest you pay on your mortgage is deductible from your taxes each year if you itemize your deductions rather than taking the standard deduction which the majority of american homeowners do if you attach schedule a to your tax return you itemize what that means is that if $ 15000 of your $ 30000 in mortgage payments this year go to paying off interest on the loan then you can claim that amount as a mortgage interest deduction the interest you pay on your mortgage is deductible from your taxes each year if you itemize your deductions rather than taking the standard deduction which the majority of american homeowners do
In this figure it can be seen that there are different orders of potency for efficacy (maximal response) and affinity (potency); this is a clear indication that the structural differences in the molecules have different effects on efficacy and affinity. Figure 2.10.
Lipophilic efficiency (LiPE), sometimes referred to as ligand-lipophilicity efficiency (LLE) is a parameter used in drug design and drug discovery to evaluate the quality of research compounds, linking potency and lipophilicity in an attempt to estimate druglikeness.igh potency (high value of pIC 50) is a desirable attribute in drug candidates, as it reduces the risk of non-specific, off-target pharmacology at a given concentration. When associated with low clearance, high potency also allows for low total dose, which lowers the risk of idiosyncratic drug reaction.