One advantage of men's fashion and accessory products is that there's and an increasing trend in general of this product category. Forrester Research noted that total U.S. online retail sales of men's accessories are expected to hit $370 billion by 2017.
Biochem/physiol Actions. DAPT is a Î³-secretase inhibitor and indirectly an inhibitor of Notch, a Î³-secretase substrate. Other Î³-secretase substrates include LDL receptor-related protein, E-cadherin and ErbB-4. As an inhibitor of Î³-secretase, DAPT may be useful in the study of Î²-amyloid (AÎ²) formation.
CA-MRSA usually causes skin infections but can lead to more serious consequences, such as pneumonia and infections of bones and joints. Daptomycin is active against MRSA and was approved for use in adults in 2003 for treatment of skin and skin structure infections, and for bloodstream infections three years later.