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Jackson County, Mississippi. Not to be confused with Jackson, Mississippi. Jackson County is a county located in the U.S. state of Mississippi. As of the 2010 census, the population was 139,668, making it the fifth-most populous county in Mississippi. Its county seat is Pascagoula.
Jackson County is included in the 10 fastest growing counties in the country yet offers an abundance of open spaces and unspoiled views of the state's Piedmont Region - just south of the Blue Ridge Mountains. The climate is moderate, pleasant, and enjoyable for a wide variety of outdoor activities.