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Skin cells live about two or three weeks. Colon cells have it rough: They die off after about four days. Sperm cells have a life span of only about three days, while brain cells typically last an entire lifetime (neurons in the cerebral cortex, for example, are not replaced when they die). There's nothing special or significant about a seven-year cycle, since cells are dying and being replaced all the time.
Blood isn't what keeps the brain alive per se, but rather the dissolved oxygen in the blood. Typically, the human brain can go for about 3 to 5 minutes without oxygen before irreversible brain damage begins to occur, and 9 minutes is usually the point where brain death will occur and all electrical function stops. But in certain situations, the brain can go as long as an hour without oxygen.