In our patient, suffering from a rebound radiculopa- thy due to clearly demonstrable scar tissue around the L5 root, in whom re-exploration was not a feasible option, hyaluronidase applied locally succeeded in pro- ducing periods with drastic reduction of pain where regular pharmaceutical means had failed.
About this book. Mitochondrial Medicine is a relatively new area where several disciplines from basic science to clinical medicine converge. Mitochondrial medicine deals with diseases that are related to mitochondrial dysfunction due to a number of causes from free radical damage to genetic mutation. A primary feature of mitochondrial dysfunction is impaired cellular bioenergetics.
Mitochondrial diseases are the result of either inherited or spontaneous mutations in mtDNA or nDNA which lead to altered functions of the proteins or RNA molecules that normally reside in mitochondria.