In most animals, offspring genders are determined by sex chromosomes at the time of conception. But alligators and other crocodilian species, as well as some turtles and lizards, do not have sex chromosomes. Instead, the sex of the young is determined by the temperature at which the eggs incubate during a critical ...
Nexgard: in a field study of 415 dogs, reactions included vomiting, dry/flaky skin, diarrhea, lethargy, and lack of appetite. These reactions occurred in 4% or less of dogs. Three dogs in the study had a history of seizures; 2 out of 3 experienced one or more seizures after taking Nexgard.
In the margin of safety study, Nexgard was given at 1, 3, and 5x the recommended dose, with only vomiting noted as an adverse event. All lab data collected from all dogs was normal. Bravecto: in a field study of 294 dogs, reactions included vomiting, decreased appetite, diarrhea, lethargy, and increased drinking.