Itâs now time to start the process of claiming your tax refund if you are a subcontractor working within the construction industry and have been paying tax, in advance, through the Construction Industry Scheme (âCISâ).
1 Besides breast cancer, an abnormal RINT1 gene is linked to Lynch-syndrome cancers: cancer of the colon, rectum, stomach, small intestine, liver, gallbladder ducts, upper urinary tract, brain, ovaries, lining of the uterus, and skin.
Some forms of cancer occur early in life and are associated with mutations in a single gene. For example, retinoblastoma, which is a childhood form of retinal cancer, is caused by mutations in the RB1 gene, which is a tumor suppressor gene.