Recent reports have identified EPCAM deletions in patients with Lynch syndrome. As the data about EPCAM and LS is rapidly changing, consider consulting with a genetics specialist. â¢ If no mutation is found, follow up with MSH6 genetic testing. If only MSH6 is absent â¢ If only MSH6 is absent, the patient may have LS.
Progesterone is one of the dominant sex hormones in females, and it helps maintain a pregnancy by preventing the contraction of the uterus or womb. Progesterone can lead to constipation by slowing the passage of digested food through the intestines.
Both the progesterone IUD and copper IUD prevent pregnancy in one of two ways: 1  The released progesterone or copper creates changes in the cervical mucus and inside the uterus that kills sperm or makes them immobile. 2  The IUD changes the lining of the uterus, preventing implantation should fertilization occur.