Let's look at the details: 1  An enzyme called DNA gyrase makes a nick in the double helix and each side separates. 2  An enzyme called helicase unwinds the double-stranded DNA.  Several small proteins called single strand binding proteins (SSB) temporarily bind to each side and keep them separated.
prurigo miÂ´tis prurigo of a mild type. prurigo nodulaÂ´ris a form of neurodermatitis, usually occurring on the extremities in middle-aged women, marked by discrete, firm, rough-surfaced, dark brownish-gray, intensely itchy nodules. prurigo simÂ´plex papular urticaria.
Definition and etiology. Pruritus or itch is defined as an unpleasant sensation of the skin that provokes the urge to scratch. It is a characteristic feature of many skin diseases and an unusual sign of some systemic diseases. Pruritus may be localized or generalized and can occur as an acute or chronic condition. Itching lasting more than 6 weeks is termed chronic pruritus.