Let's look at the details: 1  An enzyme called DNA gyrase makes a nick in the double helix and each side separates. 2  An enzyme called helicase unwinds the double-stranded DNA.  Several small proteins called single strand binding proteins (SSB) temporarily bind to each side and keep them separated.
prurigo miÂ´tis prurigo of a mild type. prurigo nodulaÂ´ris a form of neurodermatitis, usually occurring on the extremities in middle-aged women, marked by discrete, firm, rough-surfaced, dark brownish-gray, intensely itchy nodules. prurigo simÂ´plex papular urticaria.
Part 2: Prurigo Pigmentosa. Prurigo pigmentosa (PP) is an inflammatory skin disease characterized by intensely pruritic papules distributed on the back, neck and chest, leaving gross reticular or net-like pigmentation that occurs mainly in young women (Figure 1). Exacerbations and recurrences are the rule.