Recent reports have identified EPCAM deletions in patients with Lynch syndrome. As the data about EPCAM and LS is rapidly changing, consider consulting with a genetics specialist. â¢ If no mutation is found, follow up with MSH6 genetic testing. If only MSH6 is absent â¢ If only MSH6 is absent, the patient may have LS.
Progesterone is one of the dominant sex hormones in females, and it helps maintain a pregnancy by preventing the contraction of the uterus or womb. Progesterone can lead to constipation by slowing the passage of digested food through the intestines.
The copper IUD. The copper IUD is a small plastic device with copper wire wrapped around it and a fine nylon string attached to the end. When the IUD is in place, the string comes out through the cervix into the top of the vagina. The hormonal (Mirena) IUD. The hormonal (Mirena) IUD is a small plastic âT-shapedâ device that contains progestogen. This is a synthetic version of the natural hormone progesterone. The device has a coating (membrane) that controls the release of the progestogen into the uterus. Like the copper IUD, it has a fine nylon string attached to the end to make checking and removing it easier. The hormonal IUD is available in Australia under the brand name Mirena.