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In brief: Naproxen. In a patient with normal kidney and liver function, Naproxen would normally be completely out of the body within 5 - 7 days. In brief: Naproxen. In a patient with normal kidney and liver function, Naproxen would normally be completely out of the body within 5 - 7 days.  In brief: Naproxen.
Immediate Release (naproxen sodium): 550 mg orally once, followed by 275 mg orally every 6 to 8 hours or 550 mg orally every 12 hours as needed. -Maximum dose: Initial total daily dose not to exceed 1375 mg; thereafter, not to exceed 1100 mg/day.