Statistical significance considers the first and third of these concerns. The middle one, bias, cannot be detected by mathematical deductive logic: it needs detailed information on the way the sample was chosen. This is dealt with in the notes on bias.
A HEIC file is a raster image saved in the High Efficiency Image Format (HEIF), a lossy compressed format. It may contain still images, image collections, image bursts, or image sequences, along with metadata that describes each image. HEIC files may also appear as .HEIF files.
Re: HEIF / .HEIC File Support in Photoshop? JJMack Oct 19, 2017 10:06 AM (in response to JROP) I'm sure Adobe want to keep make good money if it will cost more to support what you want I'm sure Adobe will pass that cost on to their users which will raise the price of products like Photoshop to offset the increased cost.