Opioid Tolerance and Addiction. After taking opioid pain medication for a while, you might find that you need more and more of the drug to achieve the same effect in reducing pain. This is called tolerance. It's not the same as addiction, which involves a compulsive use of a drug. When you use opioid medication over an extended period of time, you can develop dependence.
Supermarine Spitfires are reaching for the sky again with a new incarnation of the Second World War fighter that can trace a direct flight path to the original. The Spifire with the sharkâs teeth motif, built in Australia by Mike OâSullivan, has been flown in air shows around the world Photo: Misty Keasler.
Plymouth Valiant. For the 1962â81 Chrysler Valiant sold in Australia, New Zealand, and South Africa, see Chrysler Valiant. The Plymouth Valiant (first appearing in 1960 as simply the Valiant) is an automobile which was manufactured by the Plymouth division of the Chrysler Corporation in the United States from 1960 to 1976. It was created to give the company an entry in the compact car market emerging in the late 1950s.