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In brief: Naproxen. In a patient with normal kidney and liver function, Naproxen would normally be completely out of the body within 5 - 7 days. In brief: Naproxen. In a patient with normal kidney and liver function, Naproxen would normally be completely out of the body within 5 - 7 days.  In brief: Naproxen.
There are both prescription and Over-The-Counter (OTC) versions of naproxen sodium. When prescribed, it's usually available as a tablet, a coated tablet with a delayed release, an extended release pill, or a liquid. Most forms are taken every 8 hours, while the extended-release version is taken once a day.