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OBJECTIVE: To determine the prevalence of syndrome of inappropriate antidiuretic hormone secretion (SIADH) among older hyponatremic patients in a subacute geriatric facility, to identify patients with no apparent cause for the SIADH (idiopathic SIADH), and to determine their clinical characteristics.
The following investigations could be carried out in SIADH. urea and electrolytes; plasma and urine osmolality; urinary sodium; thyroid function tests; a short synacthen test (1) chest and skull radiographs may be useful in excluding other causes of SIADH. Note: it is important to exclude diuretic use (especially thiazides), hypothyroidism and adrenal insufficiency before the diagnosis of SIADH is made (3) Reference: