In our patient, suffering from a rebound radiculopa- thy due to clearly demonstrable scar tissue around the L5 root, in whom re-exploration was not a feasible option, hyaluronidase applied locally succeeded in pro- ducing periods with drastic reduction of pain where regular pharmaceutical means had failed.
About this book. Mitochondrial Medicine is a relatively new area where several disciplines from basic science to clinical medicine converge. Mitochondrial medicine deals with diseases that are related to mitochondrial dysfunction due to a number of causes from free radical damage to genetic mutation. A primary feature of mitochondrial dysfunction is impaired cellular bioenergetics.
1 Mitochondrial disease is a chronic, genetic disorder that occurs when the mitochondria of the cell fail to produce enough energy for cell or organ function. 2  The incidence is about 1:4000 individuals in the US.3  This is similar to the incidence of cystic fibrosis of caucasian births in the U.S. In adults, many diseases of aging have been found to have defects of mitochondrial function; these include, but are not limited to, Type 2 diabetes, Parkinson's disease, atherosclerotic heart disease, stroke, Alzheimer's disease, and cancer. 2  In addition, many medicines can injure the mitochondria.