Leukodystrophy (from the Greek words leukos:white and dystrophia: faulty development, degeneration) has come to mean a genetic metabolic disorder of the white matter. In leukodystrophies, myelin may be absent or decreased, of an abnormal structure, and unstable. Normal myelination may not be attained and what myelin is formed may break down. Some leukodystrophies affect myelin and myelin producing cells directly.
If your purpose for pruning is to enhance flowering: 1  For trees that bloom in spring, prune when their flowers fade. 2  Trees and shrubs that flower in mid-to late summer should be pruned in winter or early spring.his depends to a large extent on why you prune. Light pruning and the removal of dead wood can be done anytime.
Cut back shrubs grown primarily for their foliage, such as barberry and burning bush, almost anytime except in late autumn. New growth that starts after late-season pruning won't harden off properly before winter. If you want to do major pruning, it's best to cut the shrub back when it is dormant in winter.