5. Summary & Conclusions CBEA is a key element of enterprise systems engineering; it is the analytical framework that supports capabilities-based planning, programming, and acquisition in a systemic approach to the purposeful evolution of the enterprise.
The genes of telomerase subunits, which include TERT, TERC, DKC1 and TEP1, are located on different chromosomes. The human TERT gene (hTERT) is translated into a protein of 1132 amino acids. TERT polypeptide folds with (and carries) TERC, a non-coding RNA (451 nucleotides long).
Telomerase: Target of Immortality. Senescence An important step in oncogenesis is the establishment of immortality. Mortality is built in to somatic cells through a number of growth barriers, which includes the senescence pathway. Normal somatic cells undergo a limited number of cell divisions and then senesce.