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As a part of the initial work-up before diagnosing lymphedema, it may be necessary to exclude other potential causes of lower extremity swelling such as renal failure, hypoalbuminemia, congestive heart-failure, protein-losing nephropathy, pulmonary hypertension, obesity, pregnancy and drug-induced edema.
Unilateral oedema of the lower extremity: Introduction. Unilateral oedema of the lower extremity: Unilateral swelling of the lower extremity caused by the abnormal accumulation of tluid. See detailed information below for a list of 8 causes of Unilateral oedema of the lower extremity, Symptom Checker, including diseases and drug side effect causes. Â» Review Causes of Unilateral oedema of the lower extremity: Causes | Symptom Checker Â».