Statistical significance considers the first and third of these concerns. The middle one, bias, cannot be detected by mathematical deductive logic: it needs detailed information on the way the sample was chosen. This is dealt with in the notes on bias.
A HEIC file is a raster image saved in the High Efficiency Image Format (HEIF), a lossy compressed format. It may contain still images, image collections, image bursts, or image sequences, along with metadata that describes each image. HEIC files may also appear as .HEIF files.
So JPG is our favorite format to send or share photos among others. If the photo was in HEIC, then you have to convert it to JPG, or it is impossible to view on a PC or Mac. What is HEIC? HEIC is popular variant of HEIF, which stands for high efficiency image file format. It uses less space to store a high quality image. Now, it is a new format to replace the old ones like JPG, PNG, GIF.