Statistical significance considers the first and third of these concerns. The middle one, bias, cannot be detected by mathematical deductive logic: it needs detailed information on the way the sample was chosen. This is dealt with in the notes on bias.
A HEIC file is a raster image saved in the High Efficiency Image Format (HEIF), a lossy compressed format. It may contain still images, image collections, image bursts, or image sequences, along with metadata that describes each image. HEIC files may also appear as .HEIF files.
Akshay Daga. The Intel hex (ihex) generally known as hex file, is a format used to store machine language code in hexadecimal form. It is widely used format to store programs to be transferred to microcontrollers, ROM and EEPROM.