The Secretary of State is appointed by the President as part of his cabinet However, it is not quite so simple as that.
http://healthnewswires.com/Natural-Le... Leptin is a hormone responsible for weight loss and burning fat. The hormone is important for controlling hunger, burning calories, and for maintaining healthy body weight. When weight loss hormone imbalance happens, or if one becomes leptin resistant, it is common to gain weight, especially fat. Leptin supplements often help support healthy hormone production of leptin and weight loss. Leptin resistance affects nearly all the hormones responsible for weight control in the body.
Leptin is a hormone released from fat cells in adipose tissue. Leptin signals to the brain, in particular to an area called the hypothalamus. Leptin does not affect food intake from meal to meal but, instead, acts to alter food intake and control energy expenditure over the long term.