Primase is an enzyme that synthesizes short RNA sequences called primers. These primers serve as a starting point for DNA synthesis.Since primase produces RNA molecules, the enzyme is a type of RNA polymerase.Primase functions by synthesizing short RNA sequences that are complementary to a single-stranded piece of DNA, which serves as its template.It is critical that primers are synthesized by primase before DNA replication can occur.rimase functions by synthesizing short RNA sequences that are complementary to a single-stranded piece of DNA, which serves as its template. It is critical that primers are synthesized by primase before DNA replication can occur.
A research protocol is a document that describes the background, rationale, objectives, design, methodology, statistical considerations, and organization of a clinical research project.According to the ICH Good Clinical Practice guidelines, a protocol should include the following topics:he NIH provides many resources for protocol development to assist investigators in writing and developing clinical research protocols that are in compliance with regulatory/GCP requirements.
Manufacturing protocols are required by current good manufacturing practice (cGMP) for manufacture of foods, pharmaceuticals, and medical devices. In a clinical trial, the protocol is carefully designed to safeguard the health of the participants as well as answer specific research questions.A protocol describes what types of people may participate in the trial; the schedule of tests, procedures, medications, and dosages; and the length of the study.ormal protocols are the general rule in fields of applied science, such as environmental and medical studies that require the coordinated, standardized work of many participants. Such predefined protocols are an essential component of Good Laboratory Practice (GLP) and Good Clinical Practice (GCP) regulations.