The most common cause of vascular obstruction is a blood clot, also known as a DVT. This type of vascular problem usually occurs in one leg (not both), and leads to swelling of the soft tissues throughout the foot and ankle. The swelling can also extend further up the leg.
The hypothalamus is a part of your brain that controls body temperature. When you exercise, your body temperature increases, causing the hypothalamus to signal the brainstem to further increase your heart rate.
Increased cardiovascular fitness causes real physical changes in the structure of the heart. The muscles in the heart wall thicken, and the heart pumps more blood with each beat. That increased efficiency means an athlete's resting heart rate falls to a level that could indicate trouble in a nonathlete.