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As a part of the initial work-up before diagnosing lymphedema, it may be necessary to exclude other potential causes of lower extremity swelling such as renal failure, hypoalbuminemia, congestive heart-failure, protein-losing nephropathy, pulmonary hypertension, obesity, pregnancy and drug-induced edema.
This is caused due to sluggish blood flow in the veins of the extremities. It is usually asymptomatic. However, in a few cases patients may develop ulceration over the affected skin of the lower extremities. Warm protective clothing and warm applications on the affected area, may improve the condition.