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Sycorax is an unseen character in William Shakespeare's play The Tempest. She is a powerful witch and the mother of Caliban, one of the few native inhabitants of the island on which Prospero, the hero of the play, is stranded.
During a sword fight with the Sycorax leader on the deck of their ship, the leader cut the Doctor's right hand off and it fell somewhere in London. Because he was within the first fifteen hours of his regeneration, he regrew the hand. (TV: The Christmas Invasion)