Reg. 259 (Jan. 4, 2011). 4 See definition of applicable clinical trial at 42 U.S.C. 282(j)(1)(A). The content of this article is intended to provide a general guide to the subject matter. Specialist advice should be sought about your specific circumstances.
We identified a risk haplotype in SLC18A2 and found a consistent result in the Detroit Neighborhood Health Study (DNHS) (N=748), an epidemiologic sample of primarily African-American adults residing in urban Detroit (Goldmann et al, 2011).
Haplogroup. In molecular evolution, a haplogroup is a group of similar haplotypes that share a common ancestor having the same single nucleotide polymorphism mutation in all haplotypes. Because a haplogroup consists of similar haplotypes, it is possible to predict a haplogroup from haplotypes.An SNP test confirms a haplogroup. Haplogroups are assigned letters of the alphabet, and refinements consist of additional number and letter combinations, for example R1b1.Y-chromosome and mitochondrial DNA haplogroups have different haplogroup designations.n SNP test confirms a haplogroup. Haplogroups are assigned letters of the alphabet, and refinements consist of additional number and letter combinations, for example R1b1. Y-chromosome and mitochondrial DNA haplogroups have different haplogroup designations.