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Lithium may cause arrhythmias, or irregular heartbeat, throughout the course of therapy. If the patient experiences heart palpitations or uneven heart beat, he should seek medical care right away.
Continued use of lithium can lead to more serious kidney damage, aggravated form of diabetes insipidus. and chronic kidney failure. Chronic kidney disease is found in about one-third of people undergoing long-term lithium treatment, according to one study.