Statistical significance considers the first and third of these concerns. The middle one, bias, cannot be detected by mathematical deductive logic: it needs detailed information on the way the sample was chosen. This is dealt with in the notes on bias.
A HEIC file is a raster image saved in the High Efficiency Image Format (HEIF), a lossy compressed format. It may contain still images, image collections, image bursts, or image sequences, along with metadata that describes each image. HEIC files may also appear as .HEIF files.
File Extension HEIC. File extension HEIC is used by operating systems to recognize files with content of type HEIC. Here is some information which will get you started. To see if you have an application which support file extension HEIC you need to double click on the file. This will either open it with matching application or Windows will suggest you to look for an application for file extension HEIC either on web or on local computer. If there is no application on your computer which can open HEIC files you need to search on the internet which application can open HEIC files.