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Asthma is best described as a chronic disease that involves inflammation of the pulmonary airways and bronchial hyperresponsiveness that results in the clinical expression of a lower airway obstruction that usually is reversible.icroscopically, asthma is characterized by the presence of increased numbers of eosinophils, neutrophils, lymphocytes, and plasma cells in the bronchial tissues, bronchial secretions, and mucus. Initially, there is recruitment of leukocytes from the bloodstream to the airway by activated CD4 T-lymphocytes.
The definition of Asthma; a disease of the respiratory system, sometimes caused by allergies, with symptoms including coughing, sudden difficulty in breathing, and a tight feeling in the chest (EncartaÂ® World English Dictionary[North American Edition], 2009).he airways of the lungs are the tubes that transport air in and out of the body. Asthma patient's airways are inflamed and sensitive to certain substances. When the airway reacts to these substances the muscles in the airway start tightening and narrowing the airway and prevents the normal amount of air to the lungs.