With approximately 450,000 active CPAs in the United States, the CPA certification is the most popular professional designation for accountants. Earning the CPA designation is no easy feat, as the CPA exam is known for its extreme difficulty.
Toxicokinetics (often abbreviated as 'TK') is the description of both what rate a chemical will enter the body and what occurs to excrete and metabolize the compound once it is in the body. It is an application of pharmacokinetics to determine the relationship between the systemic exposure of a compound in experimental animals and its toxicity.
So, toxicogenomics combines toxicology with genetics, global '-omics' technologies (Box 1) and appropriate pharmacological and toxicological models (Fig. 1) to provide a comprehensive view of the function of the genetic and biochemical machinery of the cell.