The Secretary of State is appointed by the President as part of his cabinet However, it is not quite so simple as that.
http://healthnewswires.com/Natural-Le... Leptin is a hormone responsible for weight loss and burning fat. The hormone is important for controlling hunger, burning calories, and for maintaining healthy body weight. When weight loss hormone imbalance happens, or if one becomes leptin resistant, it is common to gain weight, especially fat. Leptin supplements often help support healthy hormone production of leptin and weight loss. Leptin resistance affects nearly all the hormones responsible for weight control in the body.
Leptin acts as a hormone that modulates the size of the adipose tissues in the body. It regulates food intake and body weight. Leptin also acts on specific receptors in the hypothalamus to inhibit appetite through both counteractive and stimulatory mechanisms:y contrast, when fat mass increases, so do leptin levels and appetite is suppressed until weight loss occurs. In this way leptin regulates energy intake and fat stores so that weight is maintained within a relatively narrow range. Leptin also plays an important role in regulating and modulating the onset of puberty.