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How long does lisinopril 10mg ACE Inhibitor stay in your system?   Answer   Answer The plasma half-life of lisinopril is approximately 12 hours. This means that in the average person, lisinopril should disappear from the body withâ¦in 3-4 days.
Responses (1) It doesn't matter too much what time of day you take the Lisinopril but it is a good idea to take it at the same time every day ie. at 24 hour intervals. If you are just starting treatment with Lisinopril it is probably a good idea to take the tablets in the evening with a meal to reduce side-effects.