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Colace is a brand name for the surfactant docusate sodium, a stool softener used in the treatment of constipation.
The active ingredients in Peri-Colace Â® Tablets are docusate sodium and standardized senna concentrate. These ingredients are used together to help relieve occasional constipation. Docusate sodium works to soften the stool. Ask a doctor before use if you have: 2  Stomach pain. 3  Nausea. 4  Vomiting. 5  Noticed a sudden change in bowel habits that lasts over two weeks. 6  Stop use and ask a doctor if you have rectal bleeding or fail to have a bowel movement after use of a laxative. 7  These could be signs of a serious condition.