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As a part of the initial work-up before diagnosing lymphedema, it may be necessary to exclude other potential causes of lower extremity swelling such as renal failure, hypoalbuminemia, congestive heart-failure, protein-losing nephropathy, pulmonary hypertension, obesity, pregnancy and drug-induced edema.
Lymphedema (limf-uh-DEE-muh) is a build-up of lymph fluid in the fatty tissues just under your skin. This build-up causes swelling, most often in the arms or legs. Lymphedema can also affect the face, neck, abdomen (belly), and genitals â depending on the part of the body that was treated.