In our patient, suffering from a rebound radiculopa- thy due to clearly demonstrable scar tissue around the L5 root, in whom re-exploration was not a feasible option, hyaluronidase applied locally succeeded in pro- ducing periods with drastic reduction of pain where regular pharmaceutical means had failed.
About this book. Mitochondrial Medicine is a relatively new area where several disciplines from basic science to clinical medicine converge. Mitochondrial medicine deals with diseases that are related to mitochondrial dysfunction due to a number of causes from free radical damage to genetic mutation. A primary feature of mitochondrial dysfunction is impaired cellular bioenergetics.
Mitochondrial genetics are the genetics of the DNA contained in mitochondria, eukaryotic cell organelles that generate adenosine triphosphate from pyruvic acid and are hence referred to as the powerhouses of the cell.ecause several copies of the mitochondrial genome are carried by each mitochondrion (2-10 in humans), mitochondrial mutations can be inherited maternally by mtDNA mutations which are present in mitochondria inside the oocyte before fertilization, or (as stated above) through mutations in the chromosomes.