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Comstock Lode. 1. the most valuable deposit of silver ore ever recorded, discovered in 1859 by Henry T. P. Comstock near Virginia City, Nevada.
Later, several other countries began to contribute more substantially, notably the United States with the discovery of the Comstock Lode in Nevada. Silver production continued to expand worldwide, growing from 40 to 80 million troy ounces annually by the 1870s.