The Secretary of State is appointed by the President as part of his cabinet However, it is not quite so simple as that.
http://healthnewswires.com/Natural-Le... Leptin is a hormone responsible for weight loss and burning fat. The hormone is important for controlling hunger, burning calories, and for maintaining healthy body weight. When weight loss hormone imbalance happens, or if one becomes leptin resistant, it is common to gain weight, especially fat. Leptin supplements often help support healthy hormone production of leptin and weight loss. Leptin resistance affects nearly all the hormones responsible for weight control in the body.
In general, the more fat you have, the more leptin is in your blood. But the level varies depending on many factors, including when you last ate and your sleep patterns. A study showed that rats that were given doses of leptin ended up eating less, but this effect lasted only about two weeks.