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MG can mimic ALS and other neurological disorders leading to a delay in diagnosis and treatment. MG is eminently treatable; ALS is not. Myasthenic syndrome, also known as Lambert-Eaton syndrome, can mimic ALS and its initial presentation can be similar to that of MG.
Yet, symptoms suggestive of a COPD exacerbation may be caused by other diseases or by complications of COPD. Conditions that can mimic a COPD exacerbation include pneumothorax, pneumonia, congestive heart failure, cardiac arrhythmia, pulmonary embolism, drug toxicity, metabolic disorders, stroke, and myopathy.OPD = chronic obstructive pulmonary disease; MDI = metered-dose inhaler. Once short-acting beta-2-agonist therapy is started, inhaled anticholinergic therapy (eg, ipratropium) should be initiated or increased.