Efficacy is diminished and risk of ototoxicity increased in patients with hypoproteinemia (associated with nephrotic syndrome); ototoxicity is associated with rapid injection, severe renal impairment, use of higher than recommended doses, concomitant therapy with aminoglycoside antibiotics, ethacrynic acid, or other ototoxic drugs.
www.phac-aspc.gc.ca. The Public Health Agency of Canada (French: Agence de la santÃ© publique du Canada) is an agency of the Government of Canada that is responsible for public health, emergency preparedness, and response and infectious and chronic disease control and prevention.
CÃ©DIS is an organization funded by QuÃ©becâs MinistÃ¨re de la SantÃ© et des Services sociaux that also receives a contribution from Health Canada as part of a contribution agreement for the QuÃ©bec governmentâs initiative to integrate internationally educated health professionals into the provinceâs healthcare system.