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Primary Cause of Amebiasis. The primary cause of Amebiasis is the result: 1  of transmission of an infectious agent by another person by one or more of the following: saliva, air, cough, fecal-oral route, surfaces, blood, needles, blood transfusions, sexual contact, mother to fetus, etc.
Infection with Naegleria causes the disease primary amebic meningoencephalitis (PAM), a brain inflammation, which leads to the destruction of brain tissue. Initial signs and symptoms of PAM start one to 14 days after infection and include headache, fever, nausea, vomiting and stiff neck. As the amebae cause more extensive destruction of brain tissue, this leads to confusion, lack of attention to people and surroundings, loss of balance, seizures and hallucinations.