Strain-specifictransgene methylation occurs early in mouse developmentand can be recapitulated in embryonic stem cells. Develop-ment 121: 2853â2859.Wigler, M., Levy, D., and Perucho, M. 1981. The somatic repli-cation of DNA methylation. Cell 24: 33â40.Wolffe, A.P., Jones, P.L., and Wade, P.A. 1999.
1 Toronto remains a mosaic of many languages. In 2006, forty-seven percent of the population had a mother tongue in a language other than English or French. 2  The top 5 mother tongue languages in 2006 were:  Chinese (420,000);
Toronto (/tÉµËrÉntoÊ/ , local /tÉËrÉnoÊ/ or /ËtrÉn-/) is the most populous city in Canada, and the capital of the province of Ontario.hen Europeans first arrived at the site of present-day Toronto, the vicinity was inhabited by the Iroquois, who by then had displaced the Wyandot people that had occupied the region for centuries before c. 1500.