Bridge to the New World How and when humans first came to the Americas has long been a topic of intense debate. Theories to explain the colonization of the New Worldâthe last great habitable landmass to be occupied by humansâfocus on the Bering land bridge, or Beringia, which emerged between Siberia and Alaska during the last ice age.
DNA ligase I: ligates the nascent DNA of the lagging strand after the Ribonuclease H has removed the RNA primer from the Okazaki fragments. DNA ligase III: complexes with DNA repair protein XRCC1 to aid in sealing DNA during the process of nucleotide excision repair and recombinant fragments.
Answer by VictorVenefic. Confidence votes 202. In DNA replication, DNA polymerase III is the enzyme which joins the DNA nucleotides together via phospodiester bonds. DNA Ligase is the enzyme that seals gaps in DNA during DNA Replication.