In photography, a shutter is a device that allows light to pass for a determined period of time, exposing photographic film or a light-sensitive electronic sensor to light in order to capture a permanent image of a scene.
When used in combination with an antiemetic such as metoclopramide, DHE is as effective as opiates, valproate, and ketorolac in relieving migraine headache and preventing relapses, said Dr. Chaudhry. Its bioavailability is 100% when given intramuscularly or IV and about 40% when given as a nasal spray, she added.
Dihydroergotamine (/daÉªËhaÉªdroÊ.ÉrËÉ¡ÉtÉmiËn/ dy-HY-droh-ur-GOT-É-meen; brand names D.H.E. 45 and Migranal) is an ergot alkaloid used to treat migraines. It is a derivative of ergotamine. It is administered as a nasal spray or injection and has an efficacy similar to that of sumatriptan. Nausea is a common side effect. It has similar actions to the triptans, acting as an agonist to the serotonin 5-HT(1D) receptors and causing vasoconstriction of the intracranial blood vessels, but also interacts centrally with dopamine and adrenergic receptors.