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In brief: Naproxen. In a patient with normal kidney and liver function, Naproxen would normally be completely out of the body within 5 - 7 days. In brief: Naproxen. In a patient with normal kidney and liver function, Naproxen would normally be completely out of the body within 5 - 7 days.  In brief: Naproxen.
Drugs.com explains that the initial recommended dose of naproxen is 1,000 milligrams per day; however, individuals who require additional pain relief can up the dosage to 1500 milligrams per day for a short period of time. The maximum pediatric dose of naproxen is 2.5 to 10 milligrams every 8 to 12 hours.