Primase is an enzyme that synthesizes short RNA sequences called primers. These primers serve as a starting point for DNA synthesis.Since primase produces RNA molecules, the enzyme is a type of RNA polymerase.Primase functions by synthesizing short RNA sequences that are complementary to a single-stranded piece of DNA, which serves as its template.It is critical that primers are synthesized by primase before DNA replication can occur.rimase functions by synthesizing short RNA sequences that are complementary to a single-stranded piece of DNA, which serves as its template. It is critical that primers are synthesized by primase before DNA replication can occur.
A research protocol is a document that describes the background, rationale, objectives, design, methodology, statistical considerations, and organization of a clinical research project.According to the ICH Good Clinical Practice guidelines, a protocol should include the following topics:he NIH provides many resources for protocol development to assist investigators in writing and developing clinical research protocols that are in compliance with regulatory/GCP requirements.
Carefully following the procedures and techniques outlined in the research protocol will increase the chance that the results of the research will be accurate and meaningful to others. Following the research protocol and thus the design of the study is also important because the results can then be reproduced by other researchers. The more often results are reproduced, the more likely it is that researchers and the public will accept these findings as true.