Strain-specifictransgene methylation occurs early in mouse developmentand can be recapitulated in embryonic stem cells. Develop-ment 121: 2853â2859.Wigler, M., Levy, D., and Perucho, M. 1981. The somatic repli-cation of DNA methylation. Cell 24: 33â40.Wolffe, A.P., Jones, P.L., and Wade, P.A. 1999.
1 Toronto remains a mosaic of many languages. In 2006, forty-seven percent of the population had a mother tongue in a language other than English or French. 2  The top 5 mother tongue languages in 2006 were:  Chinese (420,000);
Languages of Canada. A multitude of languages are used in Canada. According to the 2011 census, English and French are the mother tongues of 56.9% and 21.3% of Canadians respectively. 85.6% of Canadians have working knowledge of English while 30.1% have a working knowledge of French.