Causes of a burning sensation. One of the most common reasons for burning pain is damage or dysfunction in the nervous system. This system is made up of the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS is the primary command center, and includes the brain and spinal cord.
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The central nervous system (CNS) consists of the brain and spinal cord. Cerebrospinal fluid (CSF) is a clear, colorless liquid that surrounds and protects the CNS. It bathes the brain and spine in nutrients and eliminates waste products.