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1 A group of blood tests called liver function tests can be used to diagnose liver disease. Other blood tests can be done to look for specific liver problems or genetic conditions.  Imaging tests. CT scan, MRI and ultrasound can show liver damage.
Tests of Liver Function. Acute hepatocellular injury and chronic hepatocellular or cholestatic liver injury can lead to an impairment of liver function (liver failure). However, liver failure does not occur unless there is extensive liver injury. Therefore abnormal values generally imply advanced liver disease. The common tests that assess liver synthetic function are albumin and prothrombin time or INR.