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The constant acid reflux will irritate the lining of the esophagus, and complications can occur, such as Barrett's esophagus. Individuals who develop Barrett's esophagus are about 40 times more likely to develop esophageal cancer than individuals in the general population. Symptoms of Esophageal Cancer. Heartburn; Difficulty swallowing
However, if left untreated, acid reflux can cause esophagitis, a painful irritation of the esophagus that can lead to bleeding, ulcers and scarring in the esophagus. Chronic acid reflux has also been linked to Barrett's esophagus, which is an abnormal change in the cells that line the esophagus; a precursor to cancer.