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Comstock Lode. 1. the most valuable deposit of silver ore ever recorded, discovered in 1859 by Henry T. P. Comstock near Virginia City, Nevada.
In Frauds Exposed (1872), Comstock expressed concern over the general health of society and condemned those who preyed on the sick, offering their concoctions in the press. The quackery market was flooded with self-help devices and medicines.