Overnight test: After determination of baseline serum cortisol, 8 mg (typically) PO between 11:00 pm and midnight; cortisol level tested between 8:00 and 9:00 AM on following morning. IV test: After determination of baseline serum cortisol, 1 mg/hr by continuous IV infusion for 5-7 hours.
Simple: Surgical closure of a superficial wound, requiring single layer suturing of the. skin (epidermis, dermis, or subcutaneous tissue). Intermediate: 1) Surgical closure of a wound requiring closure of one or more of the. deeper subcutaneous tissue and non-muscle fascia layers in addition to the skin.
Layered Closure. A layered closure is the use of buried absorbable sutures in fascia, subcutaneous tissue, deep dermis, combined with the use of buried absorbable suture in deeper skin and tissue removes the tension from the skin edge and provides stable reduction of closure tension during healing.ayered Closure. A layered closure is the use of buried absorbable sutures in fascia, subcutaneous tissue, deep dermis, combined with the use of buried absorbable suture in deeper skin and tissue removes the tension from the skin edge and provides stable reduction of closure tension during healing.