The first recorded spelling of the family name is shown to be that of Walter de la Birche, which was dated circa 1182, in the Studies on Middle English Local Surnames, during the reign of King Henry 11, known as The Builder of Churches, 1154 - 1189.
For Downâs syndrome, a blood test called the quadruple test is available from weeks 14-20 of pregnancy. For Patauâs and Edwardsâ syndromes, you will be offered a mid-pregnancy scan that checks for physical abnormalities.
1 Down syndrome has an extra chromosome 21, referred to as trisomy 21. 2  This should be detected by PGS. 3  PGS does not test for a specific disease-such as for cystic fibrosis-that process is referred to as PGD (preimplantation genetic diagnosis).