Other mutations in the COL4A3 gene severely decrease or prevent the production of alpha3(IV) chains. As a result, there is a serious deficiency of the type IV collagen alpha3-4-5 network in the basement membranes of the kidney, inner ear, and eye.hese networks make up a large portion of basement membranes, which are thin sheet-like structures that separate and support cells in many tissues. Type IV collagen alpha3-4-5 networks play an especially important role in the basement membranes of the kidney, inner ear, and eye.
Net Financial Debt. View Financial Glossary Index. Financial debt of a company after its ending cash balance has been subtracted. If a company has 50 million in financial debt, but 30 million in cash, the net financial debt is 20 million in financial debt.
For example, assume hypothetical company Levered Co. has $40 million in long-term debt, $10 million in short-term debt, and $100 million in total assets. Levered Co. would therefore have a total debt to total assets ratio of 0.5.