Basically, the Constitution is the highest law in the United States. All other laws come from the Constitution in some way. The Constitution also provides the framework for the government of the United States. It creates things like the Presidency, the Congress, and the Supreme Court.
Glucophage XR (metformin ER) is a biguanide used to treat type II diabetes. It helps control blood sugar in combination with diet and exercise. Metformin is widely considered the first-line treatment for adult onset diabetes because it rarely causes hypoglycemia and can help with weight loss.
Metformin, marketed under the tradename Glucophage among others, is an antidiabetic medication which is taken by mouth. It is the first-line drug of choice for the treatment of type 2 diabetes, in particular, in overweight and obese people and those with normal kidney function.nterest in metformin was rekindled in the late 1940s after several reports that it could reduce blood sugar levels in people, and in 1957, French physician Jean Sterne published the first clinical trial of metformin as a treatment for diabetes.