Basically, the Constitution is the highest law in the United States. All other laws come from the Constitution in some way. The Constitution also provides the framework for the government of the United States. It creates things like the Presidency, the Congress, and the Supreme Court.
Glucophage XR (metformin ER) is a biguanide used to treat type II diabetes. It helps control blood sugar in combination with diet and exercise. Metformin is widely considered the first-line treatment for adult onset diabetes because it rarely causes hypoglycemia and can help with weight loss.
Metformin, marketed under the trade name Glucophage among others, is the first-line medication for the treatment of type 2 diabetes, particularly in people who are overweight. It is also used in the treatment of polycystic ovary syndrome. Limited evidence suggests metformin may prevent the cardiovascular disease and cancer complications of diabetes. It is not associated with weight gain. It is taken by mouth.