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A hepatocyte is a cell of the main parenchymal tissue of the liver. Hepatocytes make up 70-85% of the liver's mass.These cells are involved in: 1  Protein synthesis. 2  Protein storage. 3  Transformation of carbohydrates. 4  Synthesis of cholesterol, bile salts and phospholipids.he typical hepatocyte is cubical with sides of 20-30 Âµm, (in comparison, a human hair has a diameter of 17 to 180 Âµm). The typical volume of a hepatocyte is 3.4 x 10 â9 cm 3. Rough endoplasmic reticulum is abundant in hepatocytes, whereas most cells in the body have only small amounts.
Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor.Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin.Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration.epatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration.