The CpG PAMP is recognized by the pattern recognition receptor (PRR) Toll-Like Receptor 9 (TLR9), which is constitutively expressed only in B cells and plasmacytoid dendritic cells (pDCs) in humans and other higher primates.
The trachea is an important structure within your respiratory system, which is the organ system that delivers oxygen to your bloodstream. The trachea is a rigid tube that conducts air from your larynx to your bronchi. The trachea's rigidity is maintained by a series of cartilaginous rings arranged along its length called C-shaped cartilage rings.
The trachea, colloquially called the windpipe, is a tube that connects the pharynx and larynx to the lungs, allowing the passage of air, and so is present in almost all air-breathing animals with lungs.he trachea is lined with a layer of pseudostratified columnar epithelium, a type of epithelium. The epithelium contains goblet cells, which are glandular, modified simple columnar epithelial cells that produce mucins, the main component of mucus. Mucus helps to moisten and protect the airways.