The nucleus maintains the security of the genes and controls the functions of the entire cell by regulating gene expression. This is why the nucleus is sometimes referred to as the control center, or the brain, of the cell.
Patagonia - region in southern South America between the Andes and the South Atlantic. Argentina, Argentine Republic - a republic in southern South America; second largest country in South America.
Which means Patagonia is still the biggest One Percent company. New Belgium Brewing of Fort Collins, Colorado, brewer of Fat Tire Amber Ale, is probably the next biggest business after Patagonia.