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Causes of Iliotibial Band Syndrome. Causes of Iliotibial Band Syndrome. Iliotibial band syndrome is caused by irritation to the band of fibrous tissue that runs from the hip joint to the shinbone just below the knee joint. Risk factors include extensive running, a bowlegged stance, overpronation and leg length discrepancies.
Iliotibial band syndrome is an overuse injury causing pain on the outside part of the knee especially during running when the heel strikes the ground. Rest, ice, compression, and elevation (RICE) and anti-inflammatory medications are first-line treatments. Physical therapy may be helpful.