Cotangent Function. The cosecant function given by. and its period, phase shift, asymptotes domain and range are explored interactively. An applet is used, where parameters a, b, c and d are changed to investigate their effects on the graph of f.
Muscles can also become weak and joint stiffness can occur. Because of the generalized, systemic nature of CREST syndrome, it can also affect almost any organ in the body, such as the heart, lungs, and kidneys. Symptoms can include chest pain and hematuria.
Primary biliary cirrhosis may be associated with CREST syndrome. Renal crises rarely occur in persons with limited scleroderma (1%); they manifest accelerated hypertension, renal failure, and microangiopathic hemolytic anemia. Entrapment neurologic syndromes (eg, carpal tunnel syndrome) occur.