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The quad screen is usually done between 15 and 20 weeks of pregnancy. You'll have a blood sample taken and sent to a lab for analysis. Results are usually available in about a week. The test measures the levels of four substances in your blood: 1  alpha-fetoprotein (AFP), a protein made by the baby.
If you're measuring large, you can request a dating scan which will determine whether your estimated due date is correct and whether you really are carrying twins. Most women would not have an ultrasound scan until later, at 11 or 12 weeks of pregnancy.