The CpG PAMP is recognized by the pattern recognition receptor (PRR) Toll-Like Receptor 9 (TLR9), which is constitutively expressed only in B cells and plasmacytoid dendritic cells (pDCs) in humans and other higher primates.
The trachea is an important structure within your respiratory system, which is the organ system that delivers oxygen to your bloodstream. The trachea is a rigid tube that conducts air from your larynx to your bronchi. The trachea's rigidity is maintained by a series of cartilaginous rings arranged along its length called C-shaped cartilage rings.
The trachea is a cartilaginous tubular structure of the middle respiratory tract and is more commonly known as the windpipe. It connects the inferior margin of the larynx with the lower respiratory tract or the lungs.