She had five of them during the next 4 months before her heart doctors were able to figure out the problem: She had a genetic mutation that causes clotting. The chest pains were emergency flares, letting Gregory know something was wrong. It can be tricky to know when your pain is normal and when you should worry.
1 Place a fat-trimmed 3- to 3-1/2-pound fresh beef brisket in a 13x9x2-inch baking pan. Pour the cooking liquid over the meat. 2  Cover the pan with foil.  Bake in a 325 degrees F oven about 3 hours or until tender, turning once halfway through cooking time.
I normally cook at 275* grate temp, wrap at 160*, and pull somewhere in the neighborhood of 200* to 205*. The main key is to keep the pit temp constant and allow for a rest time of 2 to 4 hours. I like to slice brisket at an internal Temp of 175* to 185*.