Activation of enzymes and other dynamic molecules: Most enzymes shuttle between conformational states that are catalytically active versus inactive, on versus off. Many hormones affect their target cells by inducing such transitions, usually causing an activation of one of more enzymes. Because enzymes are catalytic and often serve to activate additional enzymes, a seemingly small change induced by hormone-receptor binding can lead to widespread consequences within the cell.
Shanghai Weather in January. Weather: Shanghai's severe winter is at its peak in January, with an average temperature of around 2 Â°C (36 Â°F). Don't be fooled by the number, as the temperate is actually freezing because of the wind and dampness. The bone-piercing cold drives most travelers away except for the most dedicated.
See Best Places to See Fall Foliage in Shanghai. Winter â Cold and Dry Weather: Winter is from December to February of the next year. Winter in Shanghai is characterized by bitingly cold northerlies and dryness. Visit Shanghai in Winter. Temperatures: The coldest period is from late January until early February; usually during the Chinese New Year and Spring Festival.