They are at least a thousand times larger than the 1980 eruption of Mount St. Helens, which produced only 1 km3 (0.2 cu mi) of material, and at least six times larger than the 1815 eruption of Mount Tambora, the largest eruption in recent history, which produced 160 km3 (38 cu mi) of volcanic deposits.
Listen. 1  This severe homocystinuria is caused by rare MTHFR gene mutations (sometimes in combination with a second common MTHFR gene mutation). In severe MTHFR deficiency, signs and symptoms become apparent in infancy, however the condition can be milder, presenting in later childhood or adulthood.
As you probably know, mono, or infectious mononucleosis, is a common viral infection which typically occurs in teenagers and young adults. Symptoms include sore throat, swollen glands in the neck, and fatigue. Most of the time, the condition is not serious, however symptoms can linger for a long time and can result in trouble keeping up with work or school obligations.