But if the pain is severe or if you have had gallbladder pain before, you may need to have your gallbladder removed. Depending on where a stone blocks the flow of bile, symptoms can include nausea, vomiting, fever, and severe abdominal pain that lasts longer than 6 hours.ut if the pain is severe or if you have had gallbladder pain before, you may need to have your gallbladder removed. Depending on where a stone blocks the flow of bile, symptoms can include nausea, vomiting, fever, and severe abdominal pain that lasts longer than 6 hours.
A usual adult oral dose of morphine is 60-120 mg daily in divided doses, or up to 400 mg daily in opioid tolerant patients. Recreationally, daily heroin doses of 5-1500 mg have been reported, with an average daily dose of 300-500 mg.Addicts may inject heroin 2-4 times per day.Depending on the demographic region, the street purity of heroin can range from 11-72% (average U.S. purity is ~38%).ecreationally, daily heroin doses of 5-1500 mg have been reported, with an average daily dose of 300-500 mg. Addicts may inject heroin 2-4 times per day. Depending on the demographic region, the street purity of heroin can range from 11-72% (average U.S. purity is ~38%).
A patient has received morphine 5 mg subcutaneously q4-hourly regularly and in the past 24 hours, received an additional three 5 mg subcutaneous bolus breakthrough doses. To convert into and regimen of oral morphine: (Step One): Calculate total dose over 24 hours. 1  regular doses: 5 mg x 6 doses = morphine 30 mg (s/c).pioid analgesics are the cornerstone to treatment and control of severe pain. Equivalence of dose potency is not absolute and care must be taken in changing analgesics. In general, it is safer to use a lower regular dose with breakthrough analgesia rather than to convert immediately to the âequivalentâ dose.