The Courtâs opinion is correct to state, and the Supreme Court of California was careful to acknowledge, that a proponentâs standing to defend an initiative in federal court is a question of federal law. Proper resolution of the justiciability question requires, in this case, a threshold determination of state law.
SHBG and polycystic ovarian syndrome (PCOS) Sex hormone binding globulin (SHBG) is a protein that binds to both testosterone and estradiol. Its amount can vary widely in patients, and if the SHBG is either low or high, the amount of. active (bioavailable) testosterone can vary widely. Therefore, it is very important to measure.
Any medical condition that causes an imbalance in sex hormone levels can result in virilization. These conditions are likely to cause adrenal hyperplasia, an overproduction of hormones in the adrenal cortex. In some cases, the overproduction of adrenal hormones is caused by an adenoma (cancerous tumor). This type of tumor is normally located within the adrenal glands.