NSAIDs interact with the endocannabinoid system and its endocannabinoids, as COX2 have been shown to utilize endocannabinoids as substrates, and may have a key role in both the therapeutic and adverse effects of NSAIDs, as well as in NSAIDs-induced placebo responses.
Definition: An independent variable is the variable that is changed or controlled in a scientific experiment. Independent variables are the variables that the experimenter changes to test their dependent variable.
Independence (probability theory) Part of a series on Statistics. In probability theory, two events are independent, statistically independent, or stochastically independent if the occurrence of one does not affect the probability of the other. Similarly, two random variables are independent if the realization of one does not affect the probability distribution of the other.