NSAIDs interact with the endocannabinoid system and its endocannabinoids, as COX2 have been shown to utilize endocannabinoids as substrates, and may have a key role in both the therapeutic and adverse effects of NSAIDs, as well as in NSAIDs-induced placebo responses.
Definition: An independent variable is the variable that is changed or controlled in a scientific experiment. Independent variables are the variables that the experimenter changes to test their dependent variable.
independent variable. (Ä­n'dÄ­-pÄn'dÉnt) In mathematics, a variable whose value determines the value of other variables. For example, in the formula for the area of a circle, A = Ïr2, r is the independent variable, as its value determines the value of the area (A). Compare dependent variable.