Activation of enzymes and other dynamic molecules: Most enzymes shuttle between conformational states that are catalytically active versus inactive, on versus off. Many hormones affect their target cells by inducing such transitions, usually causing an activation of one of more enzymes. Because enzymes are catalytic and often serve to activate additional enzymes, a seemingly small change induced by hormone-receptor binding can lead to widespread consequences within the cell.
Shanghai Weather in January. Weather: Shanghai's severe winter is at its peak in January, with an average temperature of around 2 Â°C (36 Â°F). Don't be fooled by the number, as the temperate is actually freezing because of the wind and dampness. The bone-piercing cold drives most travelers away except for the most dedicated.
Shanghai Weather in March. Weather: It is windy in early spring, but warms up gradually. The average high and low temperatures are 12 Â°C (54 Â°F) and 5 Â°C (41 Â°F). Clothing: Sweaters and overcoats are needed, but also bring thin sweaters and long-sleeve T-shirts in case it gets warmer during the day.