In a direct Coombs' test a special antibody is added to a sample of blood. This test checks whether there are antibodies already bound to the surface of the red blood cell. If the test is positive the antibodies that are added bind to the antibodies on the surface of the cell.
The River Hull is a navigable river in the East Riding of Yorkshire in the north of England. It rises from a series of springs to the west of Driffield, and enters the Humber estuary at Kingston upon Hull.
A few miles further east of Brough is Hessle on the outskirts of Hull, where the magnificent Humber Bridge crosses the River Humber. The bridge, one of the world's longest single span suspension bridges (4,626 feet) was commenced in 1972 and opened in 1981. It links Hessle with Barton upon Humber in Lincolnshire.