Abstract. Barbiturates and the related depressant drugs, etazolate and etomidate, inhibited both the binding of [ 3 H]bicuculline methochloride (BMC) to Î³-aminobutyric acid (GABA) receptor sites and the binding of [ 3 H]Î²-carboline-3-carboxylic acid methyl ester (Î²CCM) to benzodiazepine receptor sites in mammalian brain.he barbiturate inhibition of [ 3 H]BMC binding involved a decrease in affinity which at high concentrations of barbiturates results in an effective complete loss of detectable binding. The maximal inhibition of [ 3 H]Î²CCM binding involved a more modest decrease in affinity (increase in K D from 1.35 to 1.85 nM).
Oona /oona/ [2 sylls.] as a girls' name is pronounced OO-nah. It is of Scottish, Irish and Gaelic origin. Variant of Una (Latin) one. Playwright Eugene O'Neill gave this name to his daughter.ona /oona/ [2 sylls.] as a girls' name is pronounced OO-nah. It is of Scottish, Irish and Gaelic origin. Variant of Una (Latin) one. Playwright Eugene O'Neill gave this name to his daughter.
From Wikipedia, the free encyclopedia. Oona O'Neill Chaplin, Lady Chaplin (May 14, 1925 â September 27, 1991) was the daughter of Nobel-and Pulitzer-Prize-winning American playwright Eugene O'Neill and English-born writer Agnes Boulton, and the fourth and last wife of English actor and filmmaker Charlie Chaplin.he film was never made, but O'Neill and Chaplin began a romantic relationship and married in June 1943, a month after she had turned 18.