Cotangent Function. The cosecant function given by. and its period, phase shift, asymptotes domain and range are explored interactively. An applet is used, where parameters a, b, c and d are changed to investigate their effects on the graph of f.
Muscles can also become weak and joint stiffness can occur. Because of the generalized, systemic nature of CREST syndrome, it can also affect almost any organ in the body, such as the heart, lungs, and kidneys. Symptoms can include chest pain and hematuria.
Sudden onset of high blood pressure and kidney failure is called scleroderma renal crisis. This occurs in about 20% of people with diffuse scleroderma and can also occur with limited scleroderma and CREST Syndrome. It can result in kidney failure within days to weeks.