Excessive drinking also can lead to heart muscle disease (cardiomyopathy), irregular heartbeat (arrhythmia), and stroke. Eventually, heavy alcohol use can leave the heart too weak to pump efficiently, a condition called congestive heart failure.
Ask Leo! Â» Windows Â» Windows Configuration. Thumbs.db is a thumbnail cache used by Windows Explorer to speed up some types of folder displays. You can delete it and prevent more from appearing. by Leo A. Notenboom, Â© 2007. I've seen thumbs.db files in some of my folders.
A thumbs-up or thumbs-down is a common hand gesture achieved by a closed fist held with the thumb extended upward or downward in approval or disapproval, respectively. thumbs-up or thumbs-down is a common hand gesture achieved by a closed fist held with the thumb extended upward or downward in approval or disapproval, respectively.