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A hepatocyte is a cell of the main parenchymal tissue of the liver. Hepatocytes make up 70-85% of the liver's mass.These cells are involved in: 1  Protein synthesis. 2  Protein storage. 3  Transformation of carbohydrates. 4  Synthesis of cholesterol, bile salts and phospholipids.he typical hepatocyte is cubical with sides of 20-30 Âµm, (in comparison, a human hair has a diameter of 17 to 180 Âµm). The typical volume of a hepatocyte is 3.4 x 10 â9 cm 3. Rough endoplasmic reticulum is abundant in hepatocytes, whereas most cells in the body have only small amounts.
Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor.Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Hepatocyte growth factor is essential for migration of myogenic cells and promotes their proliferation during the early periods of tongue morphogenesis in mouse embryos. 2  C/A polymorphism in intron 13 of the HGF gene is associated with susceptibility to essential hypertension in lean or female subjects.