They are at least a thousand times larger than the 1980 eruption of Mount St. Helens, which produced only 1 km3 (0.2 cu mi) of material, and at least six times larger than the 1815 eruption of Mount Tambora, the largest eruption in recent history, which produced 160 km3 (38 cu mi) of volcanic deposits.
Listen. 1  This severe homocystinuria is caused by rare MTHFR gene mutations (sometimes in combination with a second common MTHFR gene mutation). In severe MTHFR deficiency, signs and symptoms become apparent in infancy, however the condition can be milder, presenting in later childhood or adulthood.
For teenagers and young adults, symptoms of fatigue, fever and loss of appetite occur for roughly two to three weeks after the mononucleosis incubation period.In these cases, symptoms force infected individuals to refrain from school or work for a period of time.or teenagers and young adults, symptoms of fatigue, fever and loss of appetite occur for roughly two to three weeks after the mononucleosis incubation period.