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Common types of drugs used to treat heart failure include: 1  Aldosterone inhibitors. 2  Angiotensin converting enzyme (ACE) inhibitors. 3  Angiotensin II receptor blockers (ARBs). 4  Angiotensin Receptor-Neprilysin Inhibitors (ARNIs). 5  Beta-blockers. 6  Blood vessel dilators. 7  Calcium channel blockers. 8  Digoxin. 9  Diuretics.
The familiar diuretic spironolactone has taken on new life as a treatment for left-sided congestive heart failure. Spironolactone has been shown to decrease mortality in such patients who are New York Heart Association class IV.