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What are Mast Cells? Mast cells (MC) are immune system cells that live in the bone marrow and in body tissues, internal and external, such as the gastrointestinal tract, the lining of the airway, and the skin. Everyone has mast cells in their body, and they play many complex and critical roles in keeping us healthy.
The major function of mast cells is to protect the body from intruders (including allergens and parasites) by way of immediate hypersensitive reaction (the allergic cascade) - when mast cells perceive a threat, the cell disintegrates like a tiny bomb of chemicals.