The City of Holy Cross had a population of 393 as of July 1, 2017. Holy Cross ranks in the upper quartile for Population Density and the lower quartile for Diversity Index when compared to the other cities, towns and Census Designated Places (CDPs) in Iowa. See peer rankings below. The primary coordinate point for Holy Cross is located at latitude 42.6007 and longitude -90.9961 in Dubuque County. The formal boundaries for the City of Holy Cross (see map below) encompass a land area of 0.31 sq. miles and a water area of 0 sq. miles. Dubuque County is in the Central time zone (GMT -6). The elevation is 1,207 feet.
The methylenetetrahydrofolate reductase (MTHFR) mutation test is used to detect two relatively common mutations in the MTHFR gene that are associated with elevated levels of homocysteine in the blood.he MTHFR mutation test may sometimes be ordered when a person has elevated homocysteine levels, especially when the person has a personal or family history of premature cardiovascular disease or thrombosis.
Methylene tetrahydrofolate reductase is the rate-limiting enzyme in the methyl cycle, and it is encoded by the MTHFR gene. Methylenetetrahydrofolate reductase catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a cosubstrate for homocysteine remethylation to methionine. Natural variation in this gene is common in healthy people. Although some variants have been reported to influence susceptibility to occlusive vascular disease, neural tube defects, Alzheimer's