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The quad screen is usually done between 15 and 20 weeks of pregnancy. You'll have a blood sample taken and sent to a lab for analysis. Results are usually available in about a week. The test measures the levels of four substances in your blood: 1  alpha-fetoprotein (AFP), a protein made by the baby.
Ultrasound exam. At a mid-pregnancy ultrasound, usually done between 16 and 20 weeks, your baby will be carefully examined. Quad screen (second-trimester prenatal screening). Find out what the multiple marker screening test can tell you.f you'd like to find out whether your baby's a boy or a girl, you usually can at the midpregnancy ultrasound (16 to 20 weeks), unless, for example, your child's hand is covering his genitals during the scan.