In a direct Coombs' test a special antibody is added to a sample of blood. This test checks whether there are antibodies already bound to the surface of the red blood cell. If the test is positive the antibodies that are added bind to the antibodies on the surface of the cell.
The River Hull is a navigable river in the East Riding of Yorkshire in the north of England. It rises from a series of springs to the west of Driffield, and enters the Humber estuary at Kingston upon Hull.
The exact year the town was founded is not known but it was first mentioned in 1193. Renamed Kings-town upon Hull by King Edward I in 1299, Hull has been a market town, military supply port, trading hub, fishing and whaling centre, and industrial metropolis.