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n. Any of numerous olfactory filaments in the olfactory portion of the nasal mucosa that enter the olfactory bulb, where they terminate in synaptic contact with mitral cells, tufted cells, and granule cells. Also called first cranial nerve.
Once in the olfactory epithelium, odor molecules bind to olfactory receptors which are expressed in olfactory sensory neurons in the nose. Once an odorant binds to the receptor, the olfactory receptors trigger a series of signals to the cellsâ interiors that ultimately results in the opening and closing of ion channels.