Cotangent Function. The cosecant function given by. and its period, phase shift, asymptotes domain and range are explored interactively. An applet is used, where parameters a, b, c and d are changed to investigate their effects on the graph of f.
Muscles can also become weak and joint stiffness can occur. Because of the generalized, systemic nature of CREST syndrome, it can also affect almost any organ in the body, such as the heart, lungs, and kidneys. Symptoms can include chest pain and hematuria.
Background. CREST (calcinosis, Raynaud phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia) syndrome is a member of the heterogeneous group of sclerodermas, and its name is an acronym for the cardinal clinical features of the syndrome.n 1910, Thibierge and Weissenbach described the first case report of what was later called CRST (calcinosis cutis, Raynaud phenomenon, sclerodactyly, and telangiectasia) syndrome in English by Winterbauer who, in 1964, described a series of 8 patients with the features that make up the abbreviation CRST.