Diuretics have adverse effects, which mainly consist of electrolyte and metabolic abnormalities, with a few important unique adverse effects in the different classes. Loop and thiazide diuretics can cause metabolic alkalosis due to increased excretion of chloride in proportion to bicarbonate.
One of the original Welsh breeds of sheep the Balwen remains as one of the most striking and versatile of all the rare breed sheep. The sheep has a base colour of black, dark brown or dark grey. It has a white stripe running from the pole of the head to the top of the nose, four white feet and half white tail.
The Old English Sheepdog (OES) is a large breed of dog which was developed in England from early herding types of dog. The Old English Sheepdog can grow a very long coat, with fur covering the face and eyes.