Female. 1  Spaying prevent uterine infections and helps prevent breast tumors, which are cancerous in about 50% of dogs and 90% of cats. 2  Your spayed female pet wonât go into heat. While cycles can vary, female felines usually go into heat four to five days every three weeks during breeding season.
One-third of Clonazepam patients will develop tolerance to the drug in 2-4 weeks and will suffer from the Benzodiazepine Withdrawal Syndrome, a grouping of extremely painful symptoms that can last many months.
Although Clonazepam is often prescribed for long-term use, the FDA cautioned that the drugâs effectiveness for more than 9 weeks was not studied in well-controlled clinical trials. Clonazepam is a benzodiazepine that has muscle relaxant, sedative, anticonvulsant and hypnotic properties. Clonazepam is considered a âhighly potentâ benzodiazepine with a rapid onset of action meaning that it reaches peak blood levels in one to four hours after oral administration, but leaves the body in 18-60 hours. Roche Pharmaceutical made $211 million in 2011 alone for sales of Clonazepam.