Pope Julius II asked Michelangelo to paint the ceiling of the Sistine (sins-teen) chapel in 1508. The chapel was Built by Pope Sixtus IV in 1481. Which happened to be in the Vatican, is known to be the pope's headquarters in Rome.
Cardiac Output. Cardiac output is the amount of blood your heart pumps out in one minute. It is regulated by the amount of blood your heart pumps out in one contraction, or stroke volume, and the number of times your heart beats in one minute, or your heart rate.Cardiac output increases as a short-term and a long-term effect of regular aerobic exercise.Initially, cardiac output increases due to an increase in your heart rate. Then, as your aerobic fitness improves, cardiac output increases due to an increase in stroke volume and a decrease in heart rate.ardiac output increases as a short-term and a long-term effect of regular aerobic exercise. Initially, cardiac output increases due to an increase in your heart rate.
Combined with a decrease in fibrinolytic activity, these changes tend to prevent . Thus, pregnancy is a relatively hypercoagulable state, but during pregnancy neither clotting or bleeding times are abnormal. Cardiac Output increases to a similar degree as the blood volume. During the first trimester cardiac output is 30-40% higher than in the non-pregnant state. During , further increases are seen with pain in response to increased catecholamine secretion; this increase can be blunted with the institution of . Also during labour, there is an increase in intravascular volume by 300-500 ml of blood from the contracting uterus to the venous system. Following delivery this autotransfusion compensates for the blood losses and tends to further increase cardiac output by 50% of pre-delivery values. Cardiac Size/Position .