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Results. Ibuprofen affected testing values for vital teeth by masking palpation 40%, percussion 25%, and cold 25% on affected teeth with symptomatic irreversible pulpitis and symptomatic apical periodontitis. There was no observed masking effect in the placebo group on palpation, percussion, or cold values.hen comparing the masking effects of ibuprofen on all diagnostic groups versus this subset of SIRP/SAP, ibuprofen masked palpation the most (36.5% vs 40%) and percussion less (11% vs 25%) on affected teeth.