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Causes of Iliotibial Band Syndrome. Causes of Iliotibial Band Syndrome. Iliotibial band syndrome is caused by irritation to the band of fibrous tissue that runs from the hip joint to the shinbone just below the knee joint. Risk factors include extensive running, a bowlegged stance, overpronation and leg length discrepancies.
Pain on the lateral side of the knee is the most common symptom of iliotibial band syndrome and is due to inflammation of the area where the band crosses back and forth at the femoral epicondyle. Initially, there may be a sensation of stinging or needle-like pricks that are often ignored.