Abstract. Barbiturates and the related depressant drugs, etazolate and etomidate, inhibited both the binding of [ 3 H]bicuculline methochloride (BMC) to Î³-aminobutyric acid (GABA) receptor sites and the binding of [ 3 H]Î²-carboline-3-carboxylic acid methyl ester (Î²CCM) to benzodiazepine receptor sites in mammalian brain.he barbiturate inhibition of [ 3 H]BMC binding involved a decrease in affinity which at high concentrations of barbiturates results in an effective complete loss of detectable binding. The maximal inhibition of [ 3 H]Î²CCM binding involved a more modest decrease in affinity (increase in K D from 1.35 to 1.85 nM).
Oona /oona/ [2 sylls.] as a girls' name is pronounced OO-nah. It is of Scottish, Irish and Gaelic origin. Variant of Una (Latin) one. Playwright Eugene O'Neill gave this name to his daughter.ona /oona/ [2 sylls.] as a girls' name is pronounced OO-nah. It is of Scottish, Irish and Gaelic origin. Variant of Una (Latin) one. Playwright Eugene O'Neill gave this name to his daughter.
Oona O'Neill was born on May 14, 1925, in Bermuda, where her parents had relocated to six months before her birth in the hopes that it would be a good place to write during the winter. She also had an older brother, Shane Rudraighe O'Neill (1919â1977).