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I switched from Amlodipine to Losarten. Amlodipine was causing my gums to hurt, constipation, sleepiness, and pounding heart beats. The gum problem was not tolerable. I had to brush my teeth after eating anything because the pain was constant.
The bioavailability of amlodipine is not altered by the presence of food. Amlodipine is extensively (about 90%) converted to inactive metabolites via hepatic metabolism with 10% of the parent compound and 60% of the metabolites excreted in the urine.age 1 of 11 Amlodipine Besylate Tablets 2.5 mg, 5 mg and 10 mg Rx only DESCRIPTION Amlodipine besylate is the besylate salt of amlodipine, a long-acting calcium channel blocker.