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World Down Syndrome Day (WDSD) is observed around the world every year on March 21st (3/21), in recognition of the 3 copies of chromosome 21 that is present in most people living with Down syndrome.own syndrome occurs when a person lucks out and gets 3 copies of the 21st chromosome instead of the standard pair. World Down Syndrome Day is today, 3/21, to acknowledge that fact and bring awareness.
Abstract. Down syndrome (DS) is the most common live-born birth defect in humans. The genetic cause of DS is trisomy of chromosome 21. 94% of cases of DS trisomy are due to maternal chromosomal non-disjunction. Advanced maternal age has been identified as a key risk factor for DS.