Diuretics have adverse effects, which mainly consist of electrolyte and metabolic abnormalities, with a few important unique adverse effects in the different classes. Loop and thiazide diuretics can cause metabolic alkalosis due to increased excretion of chloride in proportion to bicarbonate.
Heritage Sheep. The long relationship between sheep and humans has led to the development of a large number of breeds. This diversity has allowed the species to meet a variety of environmental challenges and cultural needs. Selection for wool quality has been of primary importance in the evolution of sheep breeds.
The Old English Sheepdog (OES) is a large breed of dog which was developed in England from early herding types of dog. The Old English Sheepdog can grow a very long coat, with fur covering the face and eyes.