Activation of enzymes and other dynamic molecules: Most enzymes shuttle between conformational states that are catalytically active versus inactive, on versus off. Many hormones affect their target cells by inducing such transitions, usually causing an activation of one of more enzymes. Because enzymes are catalytic and often serve to activate additional enzymes, a seemingly small change induced by hormone-receptor binding can lead to widespread consequences within the cell.
Shanghai Weather in January. Weather: Shanghai's severe winter is at its peak in January, with an average temperature of around 2 Â°C (36 Â°F). Don't be fooled by the number, as the temperate is actually freezing because of the wind and dampness. The bone-piercing cold drives most travelers away except for the most dedicated.
Shanghai Weather in December. Rainy, windy, and cloudy days are the major weather of December in Shanghai. It seldom snows and is not as cold as some cities in northern China, but because of the strong wind and dampness, it is really freezing, especially at night. The awful weather diminishes the number of people traveling to Shanghai.