Diuretics have adverse effects, which mainly consist of electrolyte and metabolic abnormalities, with a few important unique adverse effects in the different classes. Loop and thiazide diuretics can cause metabolic alkalosis due to increased excretion of chloride in proportion to bicarbonate.
Heritage Sheep. The long relationship between sheep and humans has led to the development of a large number of breeds. This diversity has allowed the species to meet a variety of environmental challenges and cultural needs. Selection for wool quality has been of primary importance in the evolution of sheep breeds.
By the Numbers: Breaking Down the Biggest Sheep Breed The American Sheep Industry Association lists the Suffolk as the largest sheep breed in the world, with mature rams reaching weights of 400 pounds and mature ewes weighing up to 300 pounds. For context - a fully grown Suffolk ram can weigh approximately the same amount as a Welsh Pony.