But if the pain is severe or if you have had gallbladder pain before, you may need to have your gallbladder removed. Depending on where a stone blocks the flow of bile, symptoms can include nausea, vomiting, fever, and severe abdominal pain that lasts longer than 6 hours.ut if the pain is severe or if you have had gallbladder pain before, you may need to have your gallbladder removed. Depending on where a stone blocks the flow of bile, symptoms can include nausea, vomiting, fever, and severe abdominal pain that lasts longer than 6 hours.
A usual adult oral dose of morphine is 60-120 mg daily in divided doses, or up to 400 mg daily in opioid tolerant patients. Recreationally, daily heroin doses of 5-1500 mg have been reported, with an average daily dose of 300-500 mg.Addicts may inject heroin 2-4 times per day.Depending on the demographic region, the street purity of heroin can range from 11-72% (average U.S. purity is ~38%).ecreationally, daily heroin doses of 5-1500 mg have been reported, with an average daily dose of 300-500 mg. Addicts may inject heroin 2-4 times per day. Depending on the demographic region, the street purity of heroin can range from 11-72% (average U.S. purity is ~38%).
Morphine dose. Morphine sulphate used for pain relief may be injected intramuscularly in doses of 100-150 mcg/kg every 2 hours as required. For operations and anesthesia, the dose of morphine that needs to be administered depends on the duration of surgery and the severity of pain anticipated.s morphine binds to opioid receptors, molecular signalling activates the receptors to mediate certain actions. There are three important classes of opioid receptors and these are: 1  Î¼ receptor or Mu receptors-There are three subtypes of this receptor, the Î¼1, Î¼2 and Î¼3 receptors.