Abstract. Barbiturates and the related depressant drugs, etazolate and etomidate, inhibited both the binding of [ 3 H]bicuculline methochloride (BMC) to Î³-aminobutyric acid (GABA) receptor sites and the binding of [ 3 H]Î²-carboline-3-carboxylic acid methyl ester (Î²CCM) to benzodiazepine receptor sites in mammalian brain.he barbiturate inhibition of [ 3 H]BMC binding involved a decrease in affinity which at high concentrations of barbiturates results in an effective complete loss of detectable binding. The maximal inhibition of [ 3 H]Î²CCM binding involved a more modest decrease in affinity (increase in K D from 1.35 to 1.85 nM).
Oona /oona/ [2 sylls.] as a girls' name is pronounced OO-nah. It is of Scottish, Irish and Gaelic origin. Variant of Una (Latin) one. Playwright Eugene O'Neill gave this name to his daughter.ona /oona/ [2 sylls.] as a girls' name is pronounced OO-nah. It is of Scottish, Irish and Gaelic origin. Variant of Una (Latin) one. Playwright Eugene O'Neill gave this name to his daughter.
The first recorded spelling of the family name is shown to be that of Domhnal O'Neill, grandson of Niall Glundubh, which was dated circa 1000, in the Ancient Annals of Ireland, during the reign of Brian Boru, High King of Ireland, 940 - 1014. Surnames became necessary when governments introduced personal taxation.