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The quad screen is usually done between 15 and 20 weeks of pregnancy. You'll have a blood sample taken and sent to a lab for analysis. Results are usually available in about a week. The test measures the levels of four substances in your blood: 1  alpha-fetoprotein (AFP), a protein made by the baby.
During the 40 weeks of pregnancy gestation, there will be a wealth of tests offered to mom in order to predict the chances of baby being born with a birth defect. One such test is the quad marker screen. The quad marker screen is a blood test that will help to recognize the âchanceâ of baby having a birth defect. It is important for parents to understand that the quad marker screen is not a tool to diagnose a baby with a birth defect. The screen simply offers a percentile chance of the baby having a birth defect.