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IMRT has also been used in limited situations to treat breast, thyroid, lung, as well as in gastrointestinal, gynecologic malignancies and certain types of sarcomas. IMRT may also be beneficial for treating pediatric malignancies. Radiation therapy, including IMRT, stops cancer cells from dividing and growing, thus slowing or stopping tumor growth. In many cases, radiation therapy is capable of killing all of the cancer cells, thus shrinking or eliminating tumors.
IMRT is a form of radiation that is able to avoid the parotid glands while still delivering radiation to target tissues.3 This reason, as well as adverse effects or poor tolerability, could be contributors to the decline in use of amifostine for this indication. âSandra Cuellar, PharmD, BCOP.