In the evening Mozart took a turn for the worse, and his doctor, Thomas Closset, was summoned from the theater but sent word that he would come once the show was over. When he arrived, he ordered cold compresses applied to Mozartâs head, which witnesses said caused the patient to shudder.
Calcium plays a very important role in bone remodeling. In this process bone is deposited by osteoblasts and resorption is carried out by osteoclasts. In the bone deposition process bone is created by calcium and phosphate ions binding to create hydroxyapatite crystals.
Calcium in biology. Calcium ions (Ca2+) play a vital role in the physiology and biochemistry of organisms and the cell. They play an important role in signal transduction pathways, where they act as a second messenger, in neurotransmitter release from neurons, in contraction of all muscle cell types, and in fertilization. Many enzymes require calcium ions as a cofactor, those of the blood-clotting cascade being notable examples.