Pope Julius II asked Michelangelo to paint the ceiling of the Sistine (sins-teen) chapel in 1508. The chapel was Built by Pope Sixtus IV in 1481. Which happened to be in the Vatican, is known to be the pope's headquarters in Rome.
Cardiac Output. Cardiac output is the amount of blood your heart pumps out in one minute. It is regulated by the amount of blood your heart pumps out in one contraction, or stroke volume, and the number of times your heart beats in one minute, or your heart rate.Cardiac output increases as a short-term and a long-term effect of regular aerobic exercise.Initially, cardiac output increases due to an increase in your heart rate. Then, as your aerobic fitness improves, cardiac output increases due to an increase in stroke volume and a decrease in heart rate.ardiac output increases as a short-term and a long-term effect of regular aerobic exercise. Initially, cardiac output increases due to an increase in your heart rate.
Specifically, the resistance comes from the blood vessels and the contraction of the blood vessel walls. Remember that cardiac output is the amount of blood ejected by the heart in one minute. Afterload is one of four processes that make up cardiac output.The other three processes are preload (the pressure of the blood on the heart muscle fibers), contractility (the force of the contraction), and heart rate.To have more cardiac output you have to have lower afterload. Stroke volume is the actual contraction of the muscle fibers that eject the blood from the heart.fterload rises with age and hypertension (increased blood pressure). With age the arteries stiffen due to degeneration; therefore, less contraction of the ventricle occurs and less blood is ejected from the ventricle. Hypertension has a slightly different effect-especially on the left ventricle.