Cotangent Function. The cosecant function given by. and its period, phase shift, asymptotes domain and range are explored interactively. An applet is used, where parameters a, b, c and d are changed to investigate their effects on the graph of f.
Muscles can also become weak and joint stiffness can occur. Because of the generalized, systemic nature of CREST syndrome, it can also affect almost any organ in the body, such as the heart, lungs, and kidneys. Symptoms can include chest pain and hematuria.
Difficulty swallowing (esophageal dysfunction â the âEâ in CREST syndrome): limited scleroderma patients often have challenges swallowing due to poorly functioning muscles in the esophagus. This can also result in a backup of acidic stomach fluids (heartburn), which can damage the esophagus lining.