Standardized uptake value. The standardized uptake value (SUV) is a nuclear medicine term, used in positron emission tomography (PET) as well as in modern calibrated Single Photon Emission Tomography (SPECT) imaging for a (semi)quantitative analysis. Its use is particularly common in the analysis of F]fluorodeoxyglucose (F]FDG) images of cancer patients.
1). tumor-specific antigen. tumor-specific antigen (TSA) any cell-surface antigen of a tumor that does not occur on normal cells of the same origin. V antigen (Vi antigen) an antigen contained in the sheath of a bacterium, as Salmonella typhosa (the typhoid bacillus), and thought to contribute to its virulence.. any of several antigens, coded for by the viral genome, associated with transformation of infected cells by certain DNA tumor viruses. Called also tumor antigen. 2. an antigen present on human erythrocytes that is exposed by treatment with neuraminidase or contact with certain bacteria.
The main response of the immune system to tumors is to destroy the abnormal cells using killer T cells, sometimes with the assistance of helper T cells. Tumor antigens are presented on MHC class I molecules in a similar way to viral antigens. This allows killer T cells to recognize the tumor cell as abnormal.he adaptive immune response is antigen-specific and requires the recognition of specific non-self antigens during a process called antigen presentation. Antigen specificity allows for the generation of responses that are tailored to specific pathogens or pathogen-infected cells.