The Courtâs opinion is correct to state, and the Supreme Court of California was careful to acknowledge, that a proponentâs standing to defend an initiative in federal court is a question of federal law. Proper resolution of the justiciability question requires, in this case, a threshold determination of state law.
SHBG and polycystic ovarian syndrome (PCOS) Sex hormone binding globulin (SHBG) is a protein that binds to both testosterone and estradiol. Its amount can vary widely in patients, and if the SHBG is either low or high, the amount of. active (bioavailable) testosterone can vary widely. Therefore, it is very important to measure.
As you will read, sex hormone imbalances precipitated by SHBG abnormalities are associated with multiple diseases of aging in both sexes. These include cardiovascular disease (especially in women), cancer, type 2 diabetes, metabolic syndrome, and sleep apnea.