Abstract. Barbiturates and the related depressant drugs, etazolate and etomidate, inhibited both the binding of [ 3 H]bicuculline methochloride (BMC) to Î³-aminobutyric acid (GABA) receptor sites and the binding of [ 3 H]Î²-carboline-3-carboxylic acid methyl ester (Î²CCM) to benzodiazepine receptor sites in mammalian brain.he barbiturate inhibition of [ 3 H]BMC binding involved a decrease in affinity which at high concentrations of barbiturates results in an effective complete loss of detectable binding. The maximal inhibition of [ 3 H]Î²CCM binding involved a more modest decrease in affinity (increase in K D from 1.35 to 1.85 nM).
Oona /oona/ [2 sylls.] as a girls' name is pronounced OO-nah. It is of Scottish, Irish and Gaelic origin. Variant of Una (Latin) one. Playwright Eugene O'Neill gave this name to his daughter.ona /oona/ [2 sylls.] as a girls' name is pronounced OO-nah. It is of Scottish, Irish and Gaelic origin. Variant of Una (Latin) one. Playwright Eugene O'Neill gave this name to his daughter.
Their ancestor Aodh Bhuidh (Hugh Boy) O'Neil had been slain in 1283. In the modern idiom the name is spelt O'Neil, O'Neill, Neal(e), Oneile, and Nehill. On May 11th 1873, John O'Neil and Catherine Sullivan were married in Killarney, Co. Kerry.