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transient ischemic attack. a sudden episode of temporary symptoms typically due to diminished blood flow through the brain, usually defined as lasting between 24 and 48 hours. It is sometimes related to impaired blood flow through the vertebrobasilar vessels.
Ischemia is a vascular disease involving an interruption in the arterial blood supply to a tissue, organ, or extremity that, if untreated, can lead to tissue death. It can be caused by embolism, thrombosis of an atherosclerosis artery, or trauma.schemia results in tissue damage in a process known as ischemic cascade. The damage is the result of the build-up of metabolic waste products, inability to maintain cell membranes, mitochondrial damage, and eventual leakage of autolyzing proteolytic enzymes into the cell and surrounding tissues.