2. Cholera exotoxin (choleragen), produced by Vibrio cholerae (inf). This exotoxin catalyzes the ADP-ribosylation of a host cell protein called Gs that turns the synthesis of a metabolic regulator molecule callec cyclic AMP (cAMP) on and off. In this case, synthesis stays turned on.
Question: What is end-stage glaucoma, and how serious is it? Answer: End-stage glaucoma is generally the term we apply when there is very advanced disease. It is a very serious situation because that means there's not very much healthy tissue left. In other words, there has been a lot of visual damage.
Learn More. Glaucoma refers to a group of diseases -- open-angle glaucoma, angle-closure glaucoma, low-tension or normal-tension glaucoma, congenital glaucoma, and secondary glaucoma -- where cells and fibers of the optic nerve are damaged, affecting the transmission of signals from the eye to the brain. It is usually progressive.