The renal tubule consists of the proximal tubule, the loop of Henle, and the distal convoluted tubule. Each portion is responsible for a different part of reabsorption.
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Although the town was based loosely on Amboy, California (a town on Route 66 that also saw a drastic decline after the grand opening of a section of I-40; additionally, there are also suggestions of Seligman, Arizona and Gallup, New Mexico), its landmarks are said to be based on buildings in other Route 66 towns.