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Alka-Seltzer Plus Cold and Cough is a combination medicine that treats cold and flu symptoms. Aspirin relieves pain and reduces fever. Chlorpheniramine is an antihistamine that treats runny nose and watery eyes. Dextromethorphan is a cough suppressant. Phenylephrine is a decongestant that clears your sinuses.
Alka-Seltzer effervescent tablets are an antacid and analgesic combination. Aspirin, the analgesic, works by inhibiting several different chemical processes within the body causing pain and inflammation. The antacid works by neutralizing stomach acid and relieving symptoms.