DMD is caused by a mutation in the dystrophin gene -- usually a large, out-of-frame deletion. Dystrophin is a structural protein associated with the support scaffolding of plasma membrane in muscle cells. Absent dystrophin causes a weakening of muscles, particularly skeletal and cardiac muscle.
The bottom portion of Pesky's Pole, with the Green Monster in the background and Fenway Park 's right field seats in the foreground. Pesky's Pole in the late innings of Boston's 11-6 win over the Oakland Athletics on September 26, 2009. Pesky's Pole, commonly referred to as The Pesky Pole, is the nickname for the right field foul pole at Fenway Park, home of the Boston Red Sox.
Santa opens the Christmas season at Santa's Village in Rovaniemi, Finland. It wasn't the first North Pole, but it was supposed to be the biggest. The fact that it was 1,600 miles from the geographic North Pole, smack in the heart of interior Alaska, was a minor detail.