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Antibiotic allergic reactions. Around 1 in 15 people have an allergic reaction to antibiotics, especially penicillin and cephalosporins. In most cases, the allergic reaction is mild to moderate and can take the form of: a raised, itchy skin rash (urticaria, or hives)
Aspirin and penicillin could also cause anaphylactic reaction in some people. Common symptoms include facial swelling, shortness of breath, wheezing, rash, itchy skin, stomach ache, slurred speech, confusion, anxiety, and coughing. (Read: Anaphylactic attack â when an allergy can kill you)