2. Cholera exotoxin (choleragen), produced by Vibrio cholerae (inf). This exotoxin catalyzes the ADP-ribosylation of a host cell protein called Gs that turns the synthesis of a metabolic regulator molecule callec cyclic AMP (cAMP) on and off. In this case, synthesis stays turned on.
Question: What is end-stage glaucoma, and how serious is it? Answer: End-stage glaucoma is generally the term we apply when there is very advanced disease. It is a very serious situation because that means there's not very much healthy tissue left. In other words, there has been a lot of visual damage.
Glaucoma definition, Ophthalmology. abnormally high fluid pressure in the eye, most commonly caused either by blockage of the channel through which aqueous humor drains (open-angle glaucoma or chronic glaucoma) or by pressure of the iris against the lens, which traps the aqueous humor (angle-closure glaucoma or acute glaucoma) See more.