The hallmark of increased platelet destruction is increased marrow megakaryocytes or, when available, high reticulated platelet count. 1  Platelet destruction results from various immune conditions, including the following: 2  Immune thrombocytopenic purpura (ITP) 3  Thrombotic microangiopathies. 4  Post-transfusion purpura (PTP)
DRUG CLASS AND MECHANISM: Methadone is a strong, synthetic (man-made) narcotic that acts on the central nervous system (brain) in a manner similar to other narcotics. It is used in the management of narcotic addiction and for pain control.RUG CLASS AND MECHANISM: Methadone is a strong, synthetic (man-made) narcotic that acts on the central nervous system (brain) in a manner similar to other narcotics. It is used in the management of narcotic addiction and for pain control.
Like morphine and heroin, Methadone works on the opioid receptors in the brain and produces many of the same effects; is long lasting and helps prevent and stop withdrawal symptoms; it also helps block the euphoric rush from other narcotics such as fentanyl, heroin and OxyContin.