2. Cholera exotoxin (choleragen), produced by Vibrio cholerae (inf). This exotoxin catalyzes the ADP-ribosylation of a host cell protein called Gs that turns the synthesis of a metabolic regulator molecule callec cyclic AMP (cAMP) on and off. In this case, synthesis stays turned on.
Question: What is end-stage glaucoma, and how serious is it? Answer: End-stage glaucoma is generally the term we apply when there is very advanced disease. It is a very serious situation because that means there's not very much healthy tissue left. In other words, there has been a lot of visual damage.
Glaucoma is a group of eye conditions that damage the optic nerve, which is vital to good vision. This damage is often caused by an abnormally high pressure in your eye. Glaucoma is one of the leading causes of blindness in the United States. It can occur at any age but is more common in older adults. The most common form of glaucoma has no warning signs.