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Causes of Muscle weakness (Weak muscles): See detailed list of causes below. Muscle weakness (medical symptom): Weakness of the muscles or loss of tone. The list of medical condition causes of Muscle weakness (Weak muscles) includes: Muscle overuse.
The causes are many and can be divided into conditions that have either true or perceived muscle weakness. True muscle weakness is a primary symptom of a variety of skeletal muscle diseases, including muscular dystrophy and inflammatory myopathy.It occurs in neuromuscular junction disorders, such as myasthenia gravis. Muscle weakness can also be caused by low levels of potassium and other electrolytes within muscle cells.uscle weakness can also be classified as either  proximal  or  distal  based on the location of the muscles that it affects. Proximal muscle weakness affects muscles closest to the body's midline, while distal muscle weakness affects muscles further out on the limbs.