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The main target organs where parathyroid hormone exerts its effects are the bones and the kidneys. When needed, parathyroid hormone is released by the parathyroid glands into the blood and causes the bones to release calcium and increase levels in the bloodstream.
The superior parathyroid glands are most commonly located in the posterolateral aspect of the superior pole of the thyroid gland at the cricothyroidal cartilage junction. They are most commonly found 1 cm above the intersection of the inferior thyroid artery and the recurrent laryngeal nerve (see the image below).