DMD is caused by a mutation in the dystrophin gene -- usually a large, out-of-frame deletion. Dystrophin is a structural protein associated with the support scaffolding of plasma membrane in muscle cells. Absent dystrophin causes a weakening of muscles, particularly skeletal and cardiac muscle.
The bottom portion of Pesky's Pole, with the Green Monster in the background and Fenway Park 's right field seats in the foreground. Pesky's Pole in the late innings of Boston's 11-6 win over the Oakland Athletics on September 26, 2009. Pesky's Pole, commonly referred to as The Pesky Pole, is the nickname for the right field foul pole at Fenway Park, home of the Boston Red Sox.
The Big Dipper is located near the north celestial pole (almost the exact location of the North Star) and is circumpolar in most of the northern hemisphere beginning at 41degrees N. latitude (the latitude of New York City), and all latitudes farther north, meaning it does not sink below the horizon at night.