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TRH stimulation test. Prior to the availability of sensitive TSH assays, thyrotropin releasing hormone (TRH) stimulation tests were relied upon for confirming and assessing the degree of suppression in suspected hyperthyroidism. Typically, this stimulation test involves determining basal TSH levels and levels 15 to 30 minutes after an intravenous bolus of TRH.
For polar hormones, tropic hormones stimulate endocrine secretion by stimulating cell secretion; that is, exocytosis. An example is the regulation of growth hormone (GH) secretion by the tropic hormone growth hormone releasing hormone (GHRH) . GHRH is a hypophysiotropic hormone.Recall that endocrine secretion is whatever occurs to increase the amount of hormone in the circulation). An example is the hormone adrenocorticotropic hormone (ACTH) that stimulates secretion of the steroid hormone cortisol by cells of the zona fasciculata in the adrenal cortex.