2. Cholera exotoxin (choleragen), produced by Vibrio cholerae (inf). This exotoxin catalyzes the ADP-ribosylation of a host cell protein called Gs that turns the synthesis of a metabolic regulator molecule callec cyclic AMP (cAMP) on and off. In this case, synthesis stays turned on.
Question: What is end-stage glaucoma, and how serious is it? Answer: End-stage glaucoma is generally the term we apply when there is very advanced disease. It is a very serious situation because that means there's not very much healthy tissue left. In other words, there has been a lot of visual damage.
The term early-onset glaucoma is used when the disorder appears before the age of 40. Medical conditions, such as hypertension, as well as family history are risk factors for glaucoma, which is why it is most often seen in older individuals. When it strikes at a younger age, family history usually plays a role.