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Largest study to date of rare genetic variants and asthma risk finds few associations. Despite a strong suspected link between genetics and asthma, commonly found genetic mutations account for only a small part of the risk for developing the disease -- a problem known as missing heritability.
While the cause of asthma is unknown, there are a number of things that can increase your chances of developing it. These include: a family history of asthma or related allergic conditions (known as atopic conditions) such as eczema, food allergy or hay fever. having another atopic condition yourself. having bronchiolitis (a common childhood lung infection) as a child. exposure to tobacco smoke as a child.