This was the beginning of modern confirmation that we are not alone in the universe. The story involves the recovery of bodies, secrecy, and death threats. Dozens of witnesses have sworn and testified to what they saw.
Numerous experimental observations suggest that local factors play a major role in the pathophysiology of restenosis. Angioplasty is invariably associated with arterial injury that provides a potent stimulus for both platelet adhesion and platelet aggregation.umerous experimental observations suggest that local factors play a major role in the pathophysiology of restenosis. Angioplasty is invariably associated with arterial injury that provides a potent stimulus for both platelet adhesion and platelet aggregation.
Local drug delivery by stent can reduce in-stent restenosis. Vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen.After stenting, the arterial wall is almost denuded of endothelium. This loss of endothelium contributes to the smooth muscle cell (SMC) proliferation seen in restenosis, since the endothelium actively inhibits SMC hyperplasia.fter stenting, the arterial wall is almost denuded of endothelium. This loss of endothelium contributes to the smooth muscle cell (SMC) proliferation seen in restenosis, since the endothelium actively inhibits SMC hyperplasia.