The colon is filled with bacteria, yeasts and fungi, which break down the foods not digested by the small. intestine, mostly different forms of carbohydrates. These bacteria particularly enjoy undigested. carbohydrates, and the fermentation leads to gas production, hydrogen and methane expelled as flatus.
Central core disease is a disorder that affects muscles used for movement (skeletal muscles). This condition causes muscle weakness that ranges from almost unnoticeable to very severe. Most people with central core disease experience persistent, mild muscle weakness that does not worsen with time.
Many of the inherited myopathies are caused by mutations that interfere with ion channels, causing either too much or too little current from flowing through the muscle cells. These disorders (myotonia congenita, paramyotonia congenita, periodic paralysis and central core disease) are sometimes called channelopathies. Central core disease seems to damage, and thus weaken, muscles by causing an excess release of calcium from internal storage compartments. A fifth myopathy, nemaline myopathy, is caused by mutations that affect filament proteins.