Problem solving is the act of defining a problem; determining the cause of the problem; identifying, prioritizing and selecting alternatives for a solution; and implementing a solution.
Ipilimumab costs $120,000 for four treatments, and nivolumab is priced at $12,500 a month, the Wall Street Journal reported. Serious Side Effects. However, the ipilimumab with nivolumab combination comes with serious side effects, such as colitis (swelling of the colon), diarrhea and problems with the endocrine glands (which produce hormones).
Yervoy is the first drug approved for treating this indication. The FDA has not approved any new first-line medicines in over ten years. A dosage of Yervoy is expected to cost about $30,000; therapy of four infusions over three months will cost around $120,000. The drug is estimated to have a market of more than $400m in 2011.