Welcome to the NEW Baltimore County volunteer site! We encourage agencies in Baltimore County and the surrounding communities to create a profile to highlight their volunteer needs. We invite people searching for volunteer opportunities to use either the quick search tool above or register as a volunteer from the drop-down menu at the top of the page.
By inhibiting the dopamine transporter, a dopamine reuptake inhibitor increases the body's extracellular concentrations of dopamine, which in turn increases dopaminergic neurotransmission and creates feelings of pleasure or even euphoria. A dopamine reuptake inhibitor has a number of medical applications.
After maximal desensitization, the EC50 for dopamine-induced inhibition of adenylyl cyclase activity is increased greater than 20 fold (lower affinity) and the maximum inhibition is decreased to approximately 15%, representing an approximately 70% desensitization.