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Many medicines can cause acute kidney injury (acute renal failure), such as: Antibiotics. These include aminoglycosides, cephalosporins, amphotericin B, bacitracin, and vancomycin. Some blood pressure medicines. One example is ACE inhibitors, such as lisinopril and ramipril. Another is angiotensin receptor blockers.
Though ACE inhibitors belong to the medications which can cause the rise in creatinine level, they continue to be a good choice for kidney disease patients, that is because they minimize other symptoms of kidney disease. Cyclosporine. Cyclosporine can also cause rise in creatinine level. Cyclosporine is an immunosuppressant that is given to prevent rejection of transplanted organs or to help kidney disease patients to lower urine protein. In some instances, it is given to treat autoimmune disorders.