2. Cholera exotoxin (choleragen), produced by Vibrio cholerae (inf). This exotoxin catalyzes the ADP-ribosylation of a host cell protein called Gs that turns the synthesis of a metabolic regulator molecule callec cyclic AMP (cAMP) on and off. In this case, synthesis stays turned on.
Question: What is end-stage glaucoma, and how serious is it? Answer: End-stage glaucoma is generally the term we apply when there is very advanced disease. It is a very serious situation because that means there's not very much healthy tissue left. In other words, there has been a lot of visual damage.
Results are presented for the patients with POAG and LTG only. In the POAG and LTG group, all patients were white Caucasians. The mean age at presentation was 74.6 years (SD 9.6, range 49â94). The mean age at final glaucoma clinic visit was 81.9 years (SD 8.3, range 51â98).