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The innermost layer of a blood vessel wall is the tunica intima (too'ni-ka in-ti'ma; intimus = inmost), or tunica interna. It is composed of an endothelium (a simple squamous epithelium lining the blood vessel lumen) and a subendothelial layer made up of a thin layer of areolar connective tissue. The tunica media (me'de-a; medius = middle) is the middle layer of the vessel wall. It is composed of circularly arranged layers of smooth muscle cells. Sympathetic innervation causes the smooth muscle to contract, resulting in vasoconstriction (va'so-kon-strik'shun), or narrowing of the blood vessel lumen.
What type of blood vessel does not have these three layers. Terminal capillaries do not have these layers. Tunica intima is the innermost layer of endothelium and associated connective tissue. It varies in thickness and in specific vessels.Its surface is non-thrombogenic and it secretes materials to regulate blood fluidity.erminal capillaries do not have these layers. Tunica intima is the innermost layer of endothelium and associated connective tissue. It varies in thickness and in specific vessels. Its surface is non-thrombogenic and it secretes materials to regulate blood fluidity.