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When the liver becomes inflamed, conditions such as blood congestion, cell swelling (liver), increased secretion and retention of bile, and liver cell necrosis all increase the pressure to the liver membrane. This in turn causes the dull pain or discomfort in the liver area. During palpation, this area will also feel tender. The gallbladder is actually the more frequent the cause of this symptom since anatomically, gallbladder is literally buried in the lower surface of the liver.
These diseases cause liver pain with the symptoms varying depending on the condition. Liver pain location and symptoms. Liver pain is often confused with kidney pain, abdominal pain, or back pain because of its location. Liver pain is felt in the upper-right quadrant beneath your rib cage. It is usually felt as an ache that is dull, or the pains can be sharp and can sometimes be accompanied by back/shoulder pain. When to see a doctor