Sinus infections usually begin with the symptoms of a cold (for example, a runny nose, occasional cough and/or mild fever), and then develop into pain and pressure in the sinus cavities. About 7 to 10 days after initial cold-like symptoms other symptoms develop that suggest you may have a sinus infection.
The Ruins of Sescheron. The Ruins of Sescheron are available in the Adventure Mode of Diablo III. Specifically in Act III, near the Arreat Crater. They were released as part of patch 2.3. The area is designed to have a melancholy feel to it, with elements such as funerary art and pyres.
The Crumbling Ruins are located outside of Mistral City, and are filled with zombies and skeletons. Karpath Antioch went there to close a Hellgate that Xephos and Honeydew later discovered next to another portal in a room filled with The Sands when they were on a quest to save Granny Bacon, who had been afflicted.