2. Cholera exotoxin (choleragen), produced by Vibrio cholerae (inf). This exotoxin catalyzes the ADP-ribosylation of a host cell protein called Gs that turns the synthesis of a metabolic regulator molecule callec cyclic AMP (cAMP) on and off. In this case, synthesis stays turned on.
Question: What is end-stage glaucoma, and how serious is it? Answer: End-stage glaucoma is generally the term we apply when there is very advanced disease. It is a very serious situation because that means there's not very much healthy tissue left. In other words, there has been a lot of visual damage.
GLAUCOMA STAGE DEFINITIONS. Mild or Early Stage Glaucoma. ICD-9 365.71; ICD-10 7th digit â1â. â¢ Optic Nerve abnormalities consistent with glaucoma. â¢ but NO visual field abnormalities on any visual field. test. â¢ OR abnormalities present only on short-wave-. length automated perimetry or frequency doubling.