2. Cholera exotoxin (choleragen), produced by Vibrio cholerae (inf). This exotoxin catalyzes the ADP-ribosylation of a host cell protein called Gs that turns the synthesis of a metabolic regulator molecule callec cyclic AMP (cAMP) on and off. In this case, synthesis stays turned on.
Question: What is end-stage glaucoma, and how serious is it? Answer: End-stage glaucoma is generally the term we apply when there is very advanced disease. It is a very serious situation because that means there's not very much healthy tissue left. In other words, there has been a lot of visual damage.
Glaucoma is a complicated disease in which damage to the optic nerve results in vision loss. There are several forms of glaucoma; the two most common forms are primary open-angle glaucoma (POAG) and angle-closure glaucoma (ACG). Open-angle glaucoma is often called the sneak thief of sight because it has no symptoms until significant vision loss has occurred.