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Non-Hodgkin Lymphoma and the Environment. Non-Hodgkin's lymphomas are a group of cancers that start in lymphoid tissue, also called lymph or lymphatic tissue. The causes of Non-Hodgkin lymphomas are mostly unknown. Specific viruses, immune deficiency, and specific autoimmune conditions have been implicated in increased risk. However, some environmental issues, including exposures to pesticides and solvents, are also being investigated.
In most studies, however, lung carcinoma has been the most common neoplasm, accounting for approximately one-third of all malignant effusions. Breast carcinoma is the second most common. Lymphomas, including both Hodgkin's disease and non-Hodgkin's lymphoma, are also an important cause of malignant pleural effusions.pproximately 10% of malignant pleural effusions are due to lymphoma. According to reports in the early 1940s, in Hodgkin's disease, pleural effusions develop in 16% of patients, pleural thickening in 7%; the figures were, respectively, 15 and 11% in non-Hodgkin's lymphoma and 2 and 4% in leukemia (11).