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Largest study to date of rare genetic variants and asthma risk finds few associations. Despite a strong suspected link between genetics and asthma, commonly found genetic mutations account for only a small part of the risk for developing the disease -- a problem known as missing heritability.
In addition to confirming the previously identified asthma gene located on chromosome 17, researchers found another gene located on chromosome 1q31 was associated with an increased risk of childhood asthma in both children of European and African ancestry.