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Causes of Muscle weakness (Weak muscles): See detailed list of causes below. Muscle weakness (medical symptom): Weakness of the muscles or loss of tone. The list of medical condition causes of Muscle weakness (Weak muscles) includes: Muscle overuse.
Diseases of the neuromuscular system, injuries, metabolic diseases, and toxins can all cause of measurable muscle weakness. Signs and symptoms of weakness can include trouble doing daily tasks, such as grooming or writing or problems with gait and loss of balance.