2. Cholera exotoxin (choleragen), produced by Vibrio cholerae (inf). This exotoxin catalyzes the ADP-ribosylation of a host cell protein called Gs that turns the synthesis of a metabolic regulator molecule callec cyclic AMP (cAMP) on and off. In this case, synthesis stays turned on.
Question: What is end-stage glaucoma, and how serious is it? Answer: End-stage glaucoma is generally the term we apply when there is very advanced disease. It is a very serious situation because that means there's not very much healthy tissue left. In other words, there has been a lot of visual damage.
Glaucoma (ICD-9-CM category 365) is a group of conditions resulting in optic nerve damage caused by increased intraocular pressure. It can cause a gradual progression of vision loss if left untreated. Unless patients are having regular eye exams, glaucoma may go undetected because they may not experience any symptoms.