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Am Fam Physician. 2011 Feb 15;83(4):468-475. Guanfacine (Intuniv) is an extended-release, nonâcentral nervous system stimulant approved for the treatment of attention-deficit/hyperactivity disorder (ADHD) in children six to 17 years of age; however, it appears to be most effective in children 12 years or younger.
Uses. This medication is used alone or with other medications to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Guanfacine acts in the brain. It decreases certain nerve signals from the brain to the blood vessels and the heart. This causes the blood vessels to relax so that blood can flow more easily and also slows the heart rate. These effects help to lower blood pressure.