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Definition. Protein characteristic of the postsynaptic membrane. In a chemical synapse, the postsynaptic membrane is the membrane that receives a signal (binds neurotransmitter) from the presynaptic cell and responds via depolarisation or hyperpolarisation. The postsynaptic membrane is separated from the presynaptic membrane by the synaptic cleft.
exÂ·ciÂ·taÂ·toÂ·ry postsynaptic potential. n. A local change in the depolarization produced in the postsynaptic neuronal membrane in response to an excitatory impulse; summation of these depolarizations can lead to discharge of an impulse by the neuron. (ek-sÄ«'tÄ-tÅr-Ä pÅst'si-nap'tik pÅ-ten'shÄl).