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Non-Hodgkin Lymphoma and the Environment. Non-Hodgkin's lymphomas are a group of cancers that start in lymphoid tissue, also called lymph or lymphatic tissue. The causes of Non-Hodgkin lymphomas are mostly unknown. Specific viruses, immune deficiency, and specific autoimmune conditions have been implicated in increased risk. However, some environmental issues, including exposures to pesticides and solvents, are also being investigated.
Some long-term infections may increase a personâs risk of lymphoma by forcing their immune system to be constantly active. As more lymphocytes are made to fight the infection, there is a greater chance for mutations in key genes to occur, which might eventually lead to lymphoma.