Hydroxyzine HCl is a first-generation (sedating) antihistamine and works for itching by blocking histamine receptors.Its anti-anxiety activity is probably due to its effects in certain parts of the brain. This medicine can also cause relaxation of skeletal muscles.ydroxyzine HCl is a first-generation (sedating) antihistamine and works for itching by blocking histamine receptors.
The P. falciparum 3D7 nuclear genome is composed of 22.8 megabases (Mb) distributed among 14 chromosomes ranging in size from approximately 0.643 to 3.29 Mb (Fig. 1, and Supplementary Figs AâN). Thus the P. falciparum genome is almost twice the size of the genome of the fission yeast Schizosaccharomyces pombe.
Plasmodium falciparum is the deadliest of five human malaria species and responsible for the majority of malaria related deaths. There are around 300 million clinical cases occur each year resulting in at least one million deaths annually, predominantly in sub-saharan Africa. An estimated 3,000 children, under the age of five, fall victim to malaria each day and around 40% of the worlds population are at risk of infection. The canonical reference P. falciparum clone 3D7 was first published by Gardner et al. in 2002. The nuclear genome was described as 22.9 Mb and essentially complete, with 14 chromosomes, a G+C content of approximately 19%, 5268 genes and approximately 80 gaps.