The hallmark of increased platelet destruction is increased marrow megakaryocytes or, when available, high reticulated platelet count. 1  Platelet destruction results from various immune conditions, including the following: 2  Immune thrombocytopenic purpura (ITP) 3  Thrombotic microangiopathies. 4  Post-transfusion purpura (PTP)
DRUG CLASS AND MECHANISM: Methadone is a strong, synthetic (man-made) narcotic that acts on the central nervous system (brain) in a manner similar to other narcotics. It is used in the management of narcotic addiction and for pain control.RUG CLASS AND MECHANISM: Methadone is a strong, synthetic (man-made) narcotic that acts on the central nervous system (brain) in a manner similar to other narcotics. It is used in the management of narcotic addiction and for pain control.
Methadone hydrochloride is an opioid (a completely synthetic molecule), as opposed to an opiate, which is the name given to drugs which derive directly or indirectly from the opium poppy, such as morphine and heroin.