Problem solving is the act of defining a problem; determining the cause of the problem; identifying, prioritizing and selecting alternatives for a solution; and implementing a solution.
Ipilimumab costs $120,000 for four treatments, and nivolumab is priced at $12,500 a month, the Wall Street Journal reported. Serious Side Effects. However, the ipilimumab with nivolumab combination comes with serious side effects, such as colitis (swelling of the colon), diarrhea and problems with the endocrine glands (which produce hormones).
The comparison of previous melanoma therapies to Opdivo/nivolumab is the key here- mean overall survival for Opdivo? 17 months. Mean overall survival for older melanoma chemotherapies? Less than a year. Your $29k will buy you an increase in overall survival of about six months. 90 second video by IMS Health Informatics- listen for â2-6 monthsâ¦â