Fluid exchange between capillaries and the interstitial fluid. takes place between the blood and interstitial fluid across the thin endothelial walls of the capillaries. blood pressure drives fluid out of the capillaries, blood proteins pull fluid back in the capillaries by osmotic pressure. Difference in osmotic pressure and blood pressure drives fluids out of capillaries at the arteriole end and into capillaries at the venule end.
Premarket approval (PMA) is the FDA process of scientific and regulatory review to evaluate the safety and effectiveness of Class III medical devices.remarket approval (PMA) is the FDA process of scientific and regulatory review to evaluate the safety and effectiveness of Class III medical devices.
Because the FDA medical device premarket approval application is the most demanding FDA submission, medical device companies may find it especially difficult to collect, manage, and process the information it comprises for submission and approval. Watch Related Videos.View ISO 3-Minute Demo (3:00).ecause the FDA medical device premarket approval application is the most demanding FDA submission, medical device companies may find it especially difficult to collect, manage, and process the information it comprises for submission and approval. Watch Related Videos. View ISO 3-Minute Demo (3:00).