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Non-Hodgkin Lymphoma and the Environment. Non-Hodgkin's lymphomas are a group of cancers that start in lymphoid tissue, also called lymph or lymphatic tissue. The causes of Non-Hodgkin lymphomas are mostly unknown. Specific viruses, immune deficiency, and specific autoimmune conditions have been implicated in increased risk. However, some environmental issues, including exposures to pesticides and solvents, are also being investigated.
1 The FeLV virus has been shown to cause lymphoma and the FIV virus can predispose infected animals to develop lymphoma. 2  Second hand smoke is also known to cause gastrointestinal lymphoma in cats--the carcinogens from the smoke are thought to settle on cat's fur, and when the cat grooms itself, get ingested. Because lymphoma is a systemic disease, chemotherapy is the preferred treatment modality. 2  In selected cases, prior to the administration of chemotherapy, radiation therapy or surgery may be used to treat lymphoma localized to a defined site. 3  It is important to understand that lymphoma is not curable.