Early rheumatoid arthritis tends to affect your smaller joints first â particularly the joints that attach your fingers to your hands and your toes to your feet. As the disease progresses, symptoms often spread to the wrists, knees, ankles, elbows, hips and shoulders. In most cases, symptoms occur in the same joints on both sides of your body.
The Arabian Peninsula plays a critical geopolitical role in the Middle East and the Arab world due to its vast reserves of oil and natural gas. Before the modern era, it was divided into four distinct regions: Hejaz, Najd, Southern Arabia and Eastern Arabia.
Prophet Muhammad and the rapid rise and spread of Islam within the Arabian Peninsula. Prophet Muhammad introduced Islam in the Arabian Peninsula from 622 to 632 CE. The religion expanded further throughout the seventh and eight centuries under the Rashidun Caliphate and the Ummayad Caliphate.