1 Make sure grill is hot â place steaks in hottest section and Sear steaks 1 to 2 minutes per side to seal in the juices. 2  Finish cooking just slightly away from the hottest area â 8 to 10 minutes per inch of thickness.
Too many antibodies. Immunoglobulin E (IgE) is a type of antibody that plays a role in the body's allergic response. People with eczema have higher-than-normal levels of it. Researchers are working to understand why people with the skin condition make too much IgE and what role this may play in the disease.
The binding of IgE to the allergen (pollen, food, metal, insect venom, or whatever else is causing it) stimulates mast cells into releasing histamines (hence the class of drugs, 'antihistamines'). This mast cell activation elicits further immune response, e.g. increased white blood cell proliferation.