6. Copper cookware. Copper leaches into food when heated, prompting the FDA to caution against using unlined copper for general use. Accordingly, the cooking surfaces are usually lined with tin, nickel or stainless steel. Coated copper cookware can lose its protective layer if damaged or scoured.
Liver disorders that causes Hepatosplenomegaly. The major liver disorders that cause hepatosplenomegaly are; Hepatitis Câ Hepatitis C is a viral liver disease that is transmitted through blood. There are many symptoms for Hepatitis C, most of which directly affect the liver and spleen.
Back to Top Causes. Tay-Sachs disease occurs when the body lacks hexosaminidase A, a protein that helps break down a chemical found in nerve tissue called gangliosides. Without this protein, gangliosides, particularly ganglioside GM2, build up in cells, especially nerve cells in the brain.Tay-Sachs disease is caused by a defective gene on chromosome 15. When both parents carry the defective Tay-Sachs gene, a child has a 25% chance of developing the disease.The child must receive two copies of the defective gene -- one from each parent -- in order to become sick.ithout this protein, gangliosides, particularly ganglioside GM2, build up in cells, especially nerve cells in the brain. Tay-Sachs disease is caused by a defective gene on chromosome 15. When both parents carry the defective Tay-Sachs gene, a child has a 25% chance of developing the disease.