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Largest study to date of rare genetic variants and asthma risk finds few associations. Despite a strong suspected link between genetics and asthma, commonly found genetic mutations account for only a small part of the risk for developing the disease -- a problem known as missing heritability.
For some people with severe asthma, no specific triggers can be identified. Asthma can develop early, often before age 5. But its symptoms can begin at any age. The condition has a genetic (inherited) component.