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Search form. Causes. The cause or causes of lymphoma are largely a mystery. There may be some genetic predisposition, or it may be caused by an environmental trigger such as pollution. There is not, however, sufficient evidence to provide a definitive answer.
This page links to information about possible environmental causes of childhood cancer and organizations that attempt to study environmental causes. Note that leukemia causes is in a separate section, linked to at the right. (Some childhood cancers, such as Wilms tumor and retinoblastoma, have a strong hereditary predilection. Genetic causes of childhood cancer are not in the scope of the links on this page.) 1  1/2002 Press Release on trends and causes: National Cancer Institute Research on Childhood Cancers.  SEER Program NCI's Surveillance, Epidemiology, and End Results (SEER) Program published in 1999.