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Often the cause of keratoconus is unknown. Some studies have found that keratoconus runs in families and that it happens more often in people with certain medical problems such as certain allergic conditions. Some think that chronic eye rubbing can cause keratoconus.eratoconus changes vision in two ways: 1  As the cornea changes from a ball shape to a cone shape, the smooth surface also becomes slightly wavy. 2  As the front of the cornea expands, the eye becomes more short-sighted so that only nearby objects can be seen clearly.
The normal cornea is clear, and any alteration in clarity signifies pathology. Pathologic changes included corneal vessels, edema, pigment, lipid or calcium deposits, inflammatory cell infiltrates, destruction from degradative enzymes, and scarring. Such changes are usually non-specific and incited by numerous causes. Pathologic responses can occur singularly, but more often several occur simultaneously. Because corneal pathologic responses are usually secondary rather than primary, resolution is best achieved by identification and treatment of the primary cause. Chronic superficial keratitis Chronic superficial keratitis (or pannus) is an immune-mediated keratitis with genetic and environmental influencing factors. High altitude and ultraviolet radiation are the greatest environmental risk factors, and the most severe cases in this country occur in states such as Utah and Colorado.