In addition to the purchase price of a property in France, and the various expenses, commissions, and taxes that that purchase entails, there is a further series of outlays that will arise out of your purchase.
When an enzyme binds its substrate, it forms an enzyme-substrate complex. This complex lowers the activation energy of the reaction and promotes its rapid progression by providing certain ions or chemical groups that actually form covalent bonds with molecules as a necessary step of the reaction process.
The place where the substance fits into the enzyme is called the active site and the substance that fits into the active site is called the substrate. Enzyme action occurs when the enzyme and substrate collide. During the collision the substrate slots into the active site of the enzyme.