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The main target organs where parathyroid hormone exerts its effects are the bones and the kidneys. When needed, parathyroid hormone is released by the parathyroid glands into the blood and causes the bones to release calcium and increase levels in the bloodstream.
The parathyroid glands help control calcium use and removal by the body. They do this by producing parathyroid hormone (PTH). PTH helps control calcium, phosphorus, and vitamin D levels in the blood and bone. Hypoparathyroidism occurs when the glands produce too little PTH.