2. Cholera exotoxin (choleragen), produced by Vibrio cholerae (inf). This exotoxin catalyzes the ADP-ribosylation of a host cell protein called Gs that turns the synthesis of a metabolic regulator molecule callec cyclic AMP (cAMP) on and off. In this case, synthesis stays turned on.
Question: What is end-stage glaucoma, and how serious is it? Answer: End-stage glaucoma is generally the term we apply when there is very advanced disease. It is a very serious situation because that means there's not very much healthy tissue left. In other words, there has been a lot of visual damage.
P: Please define each of the stages, according to the loss of visual field and cupping. Dr. Elliot Werner: Early glaucoma is a small visual field defect, such as a paracentral scotoma. Moderate glaucoma is a more extensive defect, on only one side of the horizontal midline of the field.