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The main target organs where parathyroid hormone exerts its effects are the bones and the kidneys. When needed, parathyroid hormone is released by the parathyroid glands into the blood and causes the bones to release calcium and increase levels in the bloodstream.
The key purpose of the parathyroid glands is to keep the calcium and phosphorus in the blood at a constant, normal level. If, for example, the blood calcium becomes low, the parathyroid gland will respond by secreting more PTH. This extra PTH then will pull calcium from the bones, correcting the low blood level.