The hallmark of increased platelet destruction is increased marrow megakaryocytes or, when available, high reticulated platelet count. 1  Platelet destruction results from various immune conditions, including the following: 2  Immune thrombocytopenic purpura (ITP) 3  Thrombotic microangiopathies. 4  Post-transfusion purpura (PTP)
DRUG CLASS AND MECHANISM: Methadone is a strong, synthetic (man-made) narcotic that acts on the central nervous system (brain) in a manner similar to other narcotics. It is used in the management of narcotic addiction and for pain control.RUG CLASS AND MECHANISM: Methadone is a strong, synthetic (man-made) narcotic that acts on the central nervous system (brain) in a manner similar to other narcotics. It is used in the management of narcotic addiction and for pain control.
Methadone is a medication used in medication-assisted treatment (MAT) to help people reduce or quit their use of heroin or other opiates. Methadone has been used for decades to treat people who are addicted to heroin and narcotic pain medicines. When taken as prescribed, it is safe and effective.