Problem solving is the act of defining a problem; determining the cause of the problem; identifying, prioritizing and selecting alternatives for a solution; and implementing a solution.
Ipilimumab costs $120,000 for four treatments, and nivolumab is priced at $12,500 a month, the Wall Street Journal reported. Serious Side Effects. However, the ipilimumab with nivolumab combination comes with serious side effects, such as colitis (swelling of the colon), diarrhea and problems with the endocrine glands (which produce hormones).
While the Committee found that the evidence showed a significant improvement in overall survival rates in the short term after treatment with Opdivo (nivolumab), it concluded that its value for money âwas considerably aboveâ that which is usually considered to be a cost-effective use of NHS resources.