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Figuring out how many calories you burn when running is, on a simple level, a fairly straightforward calculation. Most experts (and lots of studies) suggest that a person of average weight burns about 100 calories in a mile of running.
Distance for 10 Pounds. Knowing the weight-loss basics, you can calculate the milage necessary to lose 10 pounds with some simple math. Walking at 4 mph, a very brisk pace, a 155-pound person burns about 334 calories per hour, which works out to 83.5 calories per mile.