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The numerical aperture of a microscope objective defines the objective's resolution. Each microscope objective has a minimum and maximum magnification necessary for the details in an image to be resolved. A simple formula for the minimum value is (500 x NA). And for the maximum magnification (1000 x NA).
For a single-mode fiber, the NA is typically of the order of 0.1, but can vary roughly between 0.05 and 0.4. Multimode fibers typically have a higher numerical aperture of e.g. 0.3. Very high values are possible for photonic crystal fibers.