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By inhibiting the dopamine transporter, a dopamine reuptake inhibitor increases the body's extracellular concentrations of dopamine, which in turn increases dopaminergic neurotransmission and creates feelings of pleasure or even euphoria. A dopamine reuptake inhibitor has a number of medical applications.
Re-uptake is something that happens soon after a neuron transmits the dopamine meaning it actually sucks it all back. This is to prevent too much dopamine being transmitted from one neuron to another. Reuptake (by the neuron giving the dopamine) reduces the amount of dopamine in the brain.So if reuptake is inhibited then there is likely to be MORE dopamine transmitted through the neurons in the brain because the giving neuron doesn't suck excess dopamine back. Re-uptake means there's less transmitted in the brain.euptake (by the neuron giving the dopamine) reduces the amount of dopamine in the brain. So if reuptake is inhibited then there is likely to be MORE dopamine transmitted through the neurons in the brain because the giving neuron doesn't suck excess dopamine back.