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Natural killer cells or NK cells are a type of cytotoxic lymphocyte critical to the innate immune system.his role of NK cells is critical to immune success particularly because T cells are unable to recognize pathogens in the absence of surface antigens. Tumor cell detection results in activation of NK cells and consequent cytokine production and release.
T cells are named such because these lymphocytes mature in the thymus; B cells (named for the bursa of Fabricius in which they mature in bird species) are thought to mature in the bone marrow in humans. T and B lymphocytes differ from NK cells in that they are the principal cells involved in the adaptive immune system.he large granular lymphocytes are more commonly known as the natural killer cells (NK cells). The small lymphocytes are the T cells and B cells. Lymphocytes play an important and integral role in the body's defenses.