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In genetics, a biomarker (identified as genetic marker) is a DNA sequence that causes disease or is associated with susceptibility to disease. They can be used to create genetic maps of whatever organism is being studied.ne example of a commonly used biomarker in medicine is prostate-specific antigen (PSA). This marker can be measured as a proxy of prostate size with rapid changes potentially indicating cancer.
A. Genomic Biomarker (2.1) 1. Definition (2.1.1) A genomic biomarker is defined as follows: A measurable DNA and/or RNA characteristic that is an indicator of normal. biologic processes, pathogenic processes, and/or response to therapeutic or other. 2.iomarker is key to understanding the definitions of pharmacogenomics and pharmacogenetics. and is therefore introduced in this guidance first. Additional information useful to an. understanding of aspects covered by each of the definitions is also provided.