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Calculating the Injection Dosages. According to Dr. Simeons the HCG Diet Protocol calls for daily doses of 125 IU's. Other sources have suggested higher concentrations, particularly for higher weight loss goals, but generally 125 IUs is considered the minimum dosage and 200 IUs is the maximum.
Give by IM inj slowly (1â2 mins/injection). 500mg (as two 5mL injections, one in each buttock) on Days 1, 15, 29, then once per month thereafter. For combination therapy: give with palbociclib 125mg daily with food for 21 days, followed by 7 days off; in pre/perimenopausal women: also treat with LHRH agonists. Moderate hepatic impairment: 250mg (as one 5mL injection) on Days 1, 15, 29, then once per month thereafter. Other dose modification: see full labeling.