Demyelination is often secondary to an infectious, ischemic, metabolic, or hereditary disorder or to a toxin (eg, alcohol, ethambutol). In primary demyelinating disorders, cause is unknown, but an autoimmune mechanism is suspected because the disorder sometimes follows a viral infection or viral vaccination.
For other uses, see Realm (disambiguation). A realm /ËrÉlm/ is a community or territory over which a sovereign rules; it is commonly used to describe a kingdom or other monarchical or dynastic state. The Old French word reaume, modern French royaume, was the word first adopted in English; the fixed modern spelling does not appear until the beginning of the 17th century.
1. (Government, Politics & Diplomacy) a royal domain; kingdom (now chiefly in such phrases as Peer of the Realm) 2. a field of interest, study, etc: the realm of the occult. [C13: from Old French reialme, from Latin regimen rule, influenced by Old French reial royal, from Latin rÄgÄlis regal1]