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The cause of simple liver cysts isn't known, but they may be the result of a malformation present at birth. Rarely, liver cysts may indicate a serious, underlying condition such as: 1  Polycystic liver disease, an inherited disorder.  Echinococcus infection, a parasitic infection.
Liver cysts (also called hepatic cysts) are fluid-filled sacs that occur in the liver of roughly 5% of the population. They are usually asymptomatic and often discovered by chance during an abdominal imaging procedure, like computed tomography (CT) or magnetic resonance imaging (MRI).iver cysts generally do not affect liver function and may remain asymptomatic for years. When cysts become enlarged, they can rupture or push against other organs, causing bloating, a feeling of fullness, and a sudden pain in the upper right abdominal region.