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The most common treatment for CLL is the chemotherapy drug fludarabine. This is given intravenously (through an IV) five days a week once a month, for four to six months. Although the schedule for fludarabine is rather inconvenient, it causes only modest side effects, such as fatigue.
The Bottom Line: What You Really Need to Know. Clomipramine (Anafranil) is not usually used to treat depression. It is most often used to treat OCD, panic attacks, chronic pain, bedwetting and many other problems. The usual initial dose of clomipramine is 25 mg/day divided into three doses. The dose is gradually increased to 150 mg/day or higher.