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A low RDW (below 10.2%) means that the red blood cells vary very little in size. One reason for a low RDW level is macrocytic anemia. Another cause of a low RDW level is microcytic anemia. In these two disorders the red blood cells do not vary much in size because they are either all small or all large.
If both the RDW and MCV levels are increased, there are several possible causes. One possible cause is liver disease. The liver is the largest organ in the body and is responsible for filtering (removing) harmful chemical substances, producing important chemicals for the body, and other important functions. Another cause of high RDW & MCV levels is hemolytic anemia.