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You need to wait a minimum of 18 to 24 hours, until you are in full withdrawal from the hydrocodone. Otherwise, the Suboxone on top of the hydrocodone will produce the worst withdrawal symptoms you have ever felt.
Posts: 95. Joined: November 18, 2005. Hi chels, the protocol for switching these days goes something like this...the patient should taper down to below 40mg/daily methadone, and then wait approximately 48-72 hours after the last dose of methadone to be inducted on suboxone.