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hypokinetic disease meaning, hypokinetic disease definition | English Cobuild dictionary. adj. n. a substance containing a harmless form of the germs that cause a particular disease.
Hyperkalemic periodic paralysis, also known as HYPP, is a genetically-linked muscle disease that is passed from a parent horse to a foal offspring. This disease is caused by a mutation in the sodium-channel gene which regulates muscle contractions. In horses with HYPP, the sodium channel is particularly sensitive to variations in serum potassium levels. This sensitivity can cause muscle excitability and excessive contraction of the muscle fibers leading to muscle twitching and weakness and unpredictable episodes of paralysis.