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Botox is remarkably safe, especially considering it's a powerful toxin. Occasionally, a mild headache that lasts a few hours may occur after an injection in muscles of the forehead. Very rarely, though, that headache may become excruciating and can last as long as a month.
The side effects of Botox for Migraine arenât widespread (less than 10% of patients are affected), but theyâre painfully real. According to Allerganâs own Botox for Migraine website, the most common side effect seen in Chronic Migraine clinical trials was neck pain, experienced by approximately 9% of people.