Structure [edit]. The gluteus maximus is the largest of the gluteal muscles and one of the strongest muscles in the human body. It inserts at the iliotibial band and the gluteal tuberosity of the femur.
Causes. Toxic megacolon occurs as a complication of inflammatory bowel disease, such as. and, and infections of the colon. The term toxic means that this complication occurs with infection or inflammation, and is very dangerous.1  ulcerative colitis.2  Crohn's disease.oxic megacolon occurs as a complication of inflammatory bowel disease, such as. and, and infections of the colon. The term toxic means that this complication occurs with infection or inflammation, and is very dangerous. 1  ulcerative colitis.
Hirschsprung's disease or Hirschsprung disease (HD), also called congenital megacolon or congenital aganglionic megacolon, is a form of megacolon that occurs when part or all of the large intestine or antecedent parts of the gastrointestinal tract have no ganglion cells and therefore cannot function.ypically, Hirschsprung's disease is diagnosed shortly after birth, although it may develop well into adulthood, because of the presence of megacolon, or because the baby fails to pass the first stool (meconium) within 48 hours of delivery.