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Research suggests that taking L-arginine by mouth or intravenously (by IV) for up to 8 weeks increases blood flow in people with peripheral arterial disease. However, long-term use (up to 6 months) does not improve walking speed or distance in people with peripheral arterial disease.
Following a 3-minute rest period, 60% of 1RM was placed on the chest press, and each subject completed as many repetitions as possible until failure occurred. L-arginine [alpha]-ketoglutarate does not increase muscular force output or endurance in untrained or resistance-exercise trained young females