Terminal illness is a disease that cannot be cured or adequately treated and that is reasonably expected to result in the death of the patient within a short period of time.he six-month standard is arbitrary, and best available estimates of longevity may be incorrect. Consequently, though a given patient may properly be considered terminal, this is not a guarantee that the patient will die within six months.
1 Stop metformin if the eGFR is below 30 ml/minute/1.73m2.  Prescribe metformin with caution for those at risk of a sudden deterioration in kidney function and those at risk of eGFR falling below 45ml/minute/1.73m2.
Instructions. 1  Reduce your dose, with the approval of a health-care professional. While diarrhea is most common in the initial weeks of taking metformin, reducing the dose may reduce the frequency, as it allows the body to adjust to the medication. 2  Consider switching to the extended-release version of metformin.