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Consequently, the incidence of VTE in the absence of. prophylaxis ranges from 40% to 60% (venographic rates) 7 to 14 days after major orthopedic surgery.1,11 The rate of. DVT during the same period is approximately 50% (Table.
If surgery must be performed within 1 month of an acute VTE, intravenous UFH should be administered while the INR is less than 2. If surgery must be performed within 2 weeks after an acute episode, intravenous heparin may be withheld 6 hours preoperatively and 12 hours postoperatively, if the surgery is short.