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Chargaffs rule. in dna the number of adenine units equals the number of thymine units; likewise, the number of guanine units equals the number of cytosine units.
Launch This Resource. In 1950, Erwin Chargaff published a paper stating that in the DNA of any given species, the ratio of adenine to thymine is equal, as is the ratio of cytosine to guanine. This became known as Chargaff's ratio, and it was an important clue for solving the structure of DNA. Downloads. Downloads.