Going forward, FDA has indicated a willingness to extend that accommodation further upstream in the process. Roughly 72% of the BTD denials relate at least in part to trial design or analysis problems, which suggests that sponsors must do more to engage with FDA prior to submitting their request.
Soave, from the Veneto in North East Italy, has a reputation for producing rather neutral, boring white wines. Its partly deserved. Pop into your local supermarket and buy their cheapest Soave. It will be a commodity wine, with some fresh acidity but rather neutral flavours.
Soave, mostly made from the Garganega grape, is a fruity white that often has an almond note. Verdicchio, made from the grape of the same name, has a lemony zestiness. Gavi, made from a grape called Cortese, is typically tart, with an aroma that suggests fresh limes. All pair well with herby pasta sauces like pesto, white fish or vegetable dishes. Anselmi San Vincenzo (Italy)