Side Effects and Warnings. CoQ10 is likely safe when up to 3,000 milligrams is taken by mouth daily for up to eight months in healthy people. Nanoparticular CoQ10 is safe at doses of 300 milligrams daily for up to three months.debenone is likely safe in doses of up to 60 milligrams per kilogram daily. Use cautiously in high doses over a long period of time. Use cautiously in high doses in people with liver problems. Doses of greater than 300 milligrams daily may affect levels of liver enzymes.
To stay adequately hydrated, you should drink approximately three quarts (96 ounces) of water a day. For weight loss, you should drink an additional 8 ounces of water for every 25 pounds you are over your ideal body weight. Also, water consumption should be increased in hot climates or during vigorous exercise. Please note; water will not cause you to lose weight alone.
In general, the best way to determine how much to drink (either water of a sports drink) is to: 1  Weigh yourself before and after exercise and replace fluid losses. 2  Drink 20-24 fl oz water for every 1 lb lost.