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Chargaffs rule. in dna the number of adenine units equals the number of thymine units; likewise, the number of guanine units equals the number of cytosine units.
Chargaff's ratios, 3D animation with narration. Description: Transcript: The DNA molecule is made up of very long chains of the 4 bases: A, C, G and T. In 1950, Erwin Chargaff published a paper stating that in DNA of any given species, the ratio of adenine to thymine is equal, as is the ratio of cytosine to guanine.his is known as Chargaff's ratios and it was a crucial clue that helped solve the structure of DNA. Chargaff's ratios are universal: all forms of life obey this rule. Only the balance of A-T pairs and C-G pairs varies between species.