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Researchers do know from twin studies that genetics plays a role in personality disorders. Environmental factors, such as childhood abuse, neglect and separation from caregivers, as well as brain abnormalities, emotion regulation, impulsivity, aggression and serotonin levels all play a role.ecause many personality domains are heritable, borderline personality disorder may be a result of a genotype interacting with adverse environmental factors. This would in turn lead to the expression of borderline symptoms or other dysfunctional personality traits.
Gene and cell delivery with spatially distinct transgene distributions: in vitro and in silico. We used a simple in vitro model of cardiac syncytium (neonatal rat ventricular cardiomyocytes), in which cells were transduced by either viral gene delivery (GD) or cell delivery (CD) to express an opsin, ChR2, in three spatially distinct patterns.