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Research suggests that taking L-arginine by mouth or intravenously (by IV) for up to 8 weeks increases blood flow in people with peripheral arterial disease. However, long-term use (up to 6 months) does not improve walking speed or distance in people with peripheral arterial disease.
The effects of LSD are unpredictable and depend on the amount taken; the person's personality, mood, and expectation; and the situation in which the drug is used. Effects are usually felt within 30 to 40 minutes after taking the drug. The LSD experience is often called a trip and can last up to 12 hours.