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Epididymitis is usually caused by a bacterial infection that starts in the urethra, bladder, or prostate and ultimately spreads to the epididymis. Depending on the patientâs age, the most common causes of epididymitis are sexually transmitted infection, an enlarged prostate gland, or urinary tract infections.
Epididymitis Overview. The epididymis is a long, tightly coiled tube located behind each testicle that connects the testicle to the ductus deferens and stores sperm. Acute epididymitis is inflammation of the epididymis, causing pain and swelling of the scrotum. Most cases are caused by sexually transmitted bacterial infections occurring in men age 19 to 35 years old. Chronic epididymitis refers to inflammation characterized by persistent testicular pain in the absence of scrotal swelling.