Gabapentin enacarbil extended release tablets are available under the trade name HORIZANT (R): -The recommended dosage is 600 mg orally 2 times a day. Therapy should be initiated at a dose of 600 mg orally in the morning for 3 days of therapy, then increased to 600 mg 2 times a day (1200 mg/day) on day four.
Philadelphia's central city was created in the 17th century following the plan by William Penn's surveyor Thomas Holme.
Penn made a treaty of friendship with Lenape chief Tammany under an elm tree at Shackamaxon, in what is now the city's Fishtown section. Penn named the city Philadelphia, which is Greek for brotherly love (from philos, love or friendship, and adelphos, brother).