Indications for mitochondrial DNA whole genome sequencing in the following clinical scenarios: 1  Confirmation of a suspected clinical diagnosis of a mitochondrial DNA disorder. 2  Mitochondrial DNA disorders caused by specific point mutation(s) are detected by this testing: 3  Leber hereditary optic neuropathy (LHON).
Androgen antagonists are compounds which inhibit or antagonize the biosynthesis or actions of androgens. Abbot Mcintosh 0 7 years ago Insulin lowers the level of glucose in the blood, whereas glucagon raises it; therefore, glucagon is an antagonist of insulin.
Antagonists of the 5-HT2A receptor are sometimes used as atypical antipsychotics (contrast with typical antipsychotics, which are purely dopamine antagonists). They include: 1  Cyproheptadine blocks 5-HT 2A, H1 and is a mild anticholinergic.2  Methysergide is a 5-HT 2A antagonist and nonselective 5-HT1 receptor blocker. Methysergide is a 5-HT 2A antagonist and nonselective 5-HT1 receptor blocker. 2  It causes retroperitoneal fibrosis and mediastinal fibrosis. 3  Quetiapine blocks 5-HT 2A, 5-HT1A, dopamine receptors D1 and D2, histamine receptor H1, and A1 adrenoreceptors.