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Place the pan in the microwave oven and cook the meatloaf at medium-high temperature for five minutes. Change the heat setting to high after five minutes and continue cooking for 15 minutes. Remove the meatloaf from the microwave oven after 15 minutes, and cover it with a lid or aluminum foil. After five minutes, use a meat thermometer to check the temperature. You can safely serve meatloaf if it is at least 160 degrees F.
Smooth mixture into regular sized bread pan. If you like having a sauce on top, smooth some extra ketchup over the top of the uncooked meatloaf (this step is optional). Place in oven for 35 to 40 minutes, or until meat is cooked all the way through. Let sit for 5-10 minutes before serving.