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1 A neurotoxin is a toxic agent or substance that inhibits, damages or destroys the tissues of the nervous system, especially neurons, the conducting cells of your body's central nervous system. 2  This is an example of a cytotoxin.
Medical Definition of Botulinum toxin. Botulinum toxin: A toxin produced by the bacterium Clostridium botulinum that is the most poisonous biological substance known. Botulinum toxin acts as a neurotoxin. It binds to the nerve ending at the point where the nerve joins a muscle, blocking the release by the nerve of the chemical acetylcholine (the principal neurotransmitter at the neuromuscular junction), preventing the muscle from contracting.