morphine). Since diffusion across a lipid bilayer requires that a drug be lipid-soluble, the ionized form of a drug cannot cross membranes. Thus, weak acids that are nonprotonated and weak bases that are protonated cannot diffuse across membranes. At a pH that is equal to a drugâs pKa, equal amounts of the protonated and nonprotonated forms are present. Assuming the pH is the same on both sides of a given membrane, the drug will be at equilibrium across the membrane.
Ledyba (Japanese: ã¬ãã£ã Rediba) is a Bug/Flying-type PokÃ©mon introduced in Generation II. Ledyba is a common Bug type PokÃ©mon that resembles a ladybug. It has six legs, that are all wearing gloves.
Trubbish (Japanese: ã¤ãã¯ã­ã³ Yabukuron) is a Poison-type PokÃ©mon introduced in Generation V. Trubbish is a bipedal PokÃ©mon that resembles a small garbage bag overflowing with trash. Its body is dark green and lumpy. It has two long ear-like appendages atop its head that resemble the knot at the top of a filled garbage bag. It has two small stubby feet.