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1 A neurotoxin is a toxic agent or substance that inhibits, damages or destroys the tissues of the nervous system, especially neurons, the conducting cells of your body's central nervous system. 2  This is an example of a cytotoxin.
Orexin, also called hypocretin, is a neurotransmitter that regulates arousal, wakefulness, and appetite. [1] The most common form of narcolepsy, in which the sufferer briefly loses muscle tone , is caused by a lack of orexin in the brain due to destruction of the cells that produce it. [2]