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Consequently, the incidence of VTE in the absence of. prophylaxis ranges from 40% to 60% (venographic rates) 7 to 14 days after major orthopedic surgery.1,11 The rate of. DVT during the same period is approximately 50% (Table.
2 Initial Prophylaxis hospital phase: In the multicentre study 307, Lovenox 30 mg q12h SC for 7 -10 days, initiated within 12. 24 hours postoperatively; in the single-centre study PK537, Lovenox 40 mg qd SC initiated 12. Â± 2 hours before surgery, repeated on the day of the surgery and continued for 9 Â± 2 days.