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Madison is located in Southeastern Indiana on the north bank of the Ohio River at mile 557.6, 46 miles upstream from Louisville Ky, and 88 miles downstream from Cincinnati, Ohio. By highway, Madison is 90 miles from Indianapolis the state capitol, 55 miles from Louisville, KY.
Sponsored Topics. Evansville is the third-largest city in the U.S. state of Indiana and the largest city in Southern Indiana. As of the 2010 census, the city had a total population of 117,429. It is the county seat of Vanderburgh County and the regional hub for both Southwestern Indiana and the Illinois-Indiana-Kentucky Tri-State Area.