Causes. The most common causes of megaloblastic anemia are deficiency of either cobalamin (vitamin B12) or folate (vitamin B9). These two vitamins serve as building blocks and are essential for the production of healthy cells such as the precursors to red blood cells.olate, which is also known as folic acid, is a B vitamin that is normally found in green leafy vegetables, citrus fruits, and certain grains and nuts. Folate deficiency can occur in diets that supply insufficient amounts of these foods.
After ten to fifteen years, large branches on a Bradford pear begin to split and fall if the tree has been left unpruned. The best time to prune a Bradford pear is in the first few years of its life in your landscape. If you wait much longer, limbs will grow too large and their removal could ruin the shape of the tree. This is an excellent time to grab your pruning tools and help your Bradford pear live long and prosper.
I have a Bartlett pear tree. As rule of thump I pick the large one in Mid to late August.I don't allow them to drop from the tree unless they are out of 15 feet ladder reach. I live in zone 7. As for refrigeration I never do that, leaving the bears on the kitchen counter for 7 to 10 days it gets ripen and delicious.