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The most common treatment for CLL is the chemotherapy drug fludarabine. This is given intravenously (through an IV) five days a week once a month, for four to six months. Although the schedule for fludarabine is rather inconvenient, it causes only modest side effects, such as fatigue.
1 Thrombolytics, known as blood-clot-busting drugs, are the standard medications used to open the arteries. 2  A thrombolytic drug needs to be given within 3 hours after the onset of symptoms. 3  Coronary artery bypass graft (CABG) surgery is sometimes used as an alternative to angioplasty.