Terminal illness is a disease that cannot be cured or adequately treated and that is reasonably expected to result in the death of the patient within a short period of time.he six-month standard is arbitrary, and best available estimates of longevity may be incorrect. Consequently, though a given patient may properly be considered terminal, this is not a guarantee that the patient will die within six months.
1 Stop metformin if the eGFR is below 30 ml/minute/1.73m2.  Prescribe metformin with caution for those at risk of a sudden deterioration in kidney function and those at risk of eGFR falling below 45ml/minute/1.73m2.
Metformin is a safe and effective medicine thatâs used to treat type 2 diabetes. In general, metformin is very well tolerated, but some people do experience gastrointestinal side effects, such as nausea, cramps, gassiness and diarrhea. These side effects usually go away over time, but if they do occur, they can be minimized by taking the metformin with food, rather than on an empty stomach.