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This supports the idea that in embryos from wild-type mothers, dpp H~- mutations cause the transformation of dorsal into ven-tral epidermis. If tissue determined to become dorsal epidermis dies in the dpp rim-null embryos, then one should not see ventral or lateral tissue formed in the double-mutant combination.
D. melanogaster is one of the most widely used model organisms in genetic research. This is mainly due to its being very easy to breed in a laboratory and its short generation time (around 2 weeks under good conditions). It also has only four pairs of chromosomes. Fruit flies were first used in genetic research over 100 years ago by scientists Charles W. Woodworth and W. E. Castle. In the early 20th century Thomas Hunt Morgan conducted several important genetic studies using Drosophila.