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You need to wait a minimum of 18 to 24 hours, until you are in full withdrawal from the hydrocodone. Otherwise, the Suboxone on top of the hydrocodone will produce the worst withdrawal symptoms you have ever felt.
How long after taking Tylenol 3 is it safe to take suboxone? 4 to 6 hours call a pharm that knows about saboxen as well as shot acting opiates. I have made myself wait longer and also have done it in 6 hours Tylenol 3 usally is out of yâ¦our system 4 to 6 hours afterwards no big deal.