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Alliance, Nebraska. Alliance is a city in Box Butte County, in the northwestern part of the state of Nebraska, in the Great Plains region of the United States. Its population was 8,491 at the 2010 census. It is the county seat of Box Butte County.
Alliance was founded in 1854 by the merger of three smaller communities called Williamsport (formed in 1827), Freedom (formed in 1838), and Liberty (formed in 1850). A fourth community, Mount Union, was added in 1888. Alliance was incorporated as a city in 1889.