All cells require folic acid and it can diffuse easily into human cells. But the vitamin cannot enter bacterial cells and thus bacteria must make their own. The sulfa drugs such as sulfonamides inhibit a critical enzyme--dihydropteroate synthase--in this process. Once the process is stopped, the bacteria can no longer grow.
Sonoma Countyâs natural beauty and moderate temperatures seldom dip below freezing, even in the winter. The areaâs 25- to 30-inch annual rainfall happens primarily from November through April. January â Average high /low. Inland: 58 F (14 C) / 36 F (2 C) Coast: 56 F (13 C) / 35 F (2 C)
CLIMATE OVERVIEW : Marin County, California, gets 37 inches of rain per year. The US average is 39. Snowfall is 0 inches. The average US city gets 26 inches of snow per year. The number of days with any measurable precipitation is 44. On average, there are 260 sunny days per year in Marin County, California. The July high is around 76 degrees. The January low is 42. Sperling's comfort index for Marin County is a 84 out of 100, where a higher score indicates a more comfortable year-around climate. The US average for the comfort index is 54. Our index is based on the total number of days annually within the comfort range of 70-80 degrees, and we also applied a penalty for days of excessive humidity.