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Prostaglandin F2-alpha(PGF-2 alpha) is a stable prostaglandin that stimulates the contraction of uterine and bronchial smooth muscle and produces vasoconstriction (tightening) in some blood vessels. As a pharmaceutical, the generic name of PGF-2 alpha is dinoprost.rostaglandin F2-alpha(PGF-2 alpha) is a stable prostaglandin that stimulates the contraction of uterine and bronchial smooth muscle and produces vasoconstriction (tightening) in some blood vessels. As a pharmaceutical, the generic name of PGF-2 alpha is dinoprost.
Two 5-alpha-reductase inhibitors are used to treat BPH: finasteride (Proscar) and dutasteride (Avodart). They inhibit the enzyme 5-alphareductase, which converts testosterone to dihydrotestosterone (DHT), the major male sex hormone within the cells of the prostate.