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Consequently, the incidence of VTE in the absence of. prophylaxis ranges from 40% to 60% (venographic rates) 7 to 14 days after major orthopedic surgery.1,11 The rate of. DVT during the same period is approximately 50% (Table.
prophylaxis for children and adolescents from 6 months to <16 years of age within Princess Margaret Hospital. Background: While the need for prophylaxis of VTE in adult medical and surgical patients is well established and risk factors for VTE in children and adolescents are known (Table 1), the indications for prophylaxis in children are less well defined.1,2 This is largely because there are 10-fold fewer episodes of VTE in children and the relative contribution of many risk factors is small (Table 1), making the benefit/risk of routine pharmacologic prophylaxis marginal and expensive.3-6