morphine). Since diffusion across a lipid bilayer requires that a drug be lipid-soluble, the ionized form of a drug cannot cross membranes. Thus, weak acids that are nonprotonated and weak bases that are protonated cannot diffuse across membranes. At a pH that is equal to a drugâs pKa, equal amounts of the protonated and nonprotonated forms are present. Assuming the pH is the same on both sides of a given membrane, the drug will be at equilibrium across the membrane.
Ledyba (Japanese: ã¬ãã£ã Rediba) is a Bug/Flying-type PokÃ©mon introduced in Generation II. Ledyba is a common Bug type PokÃ©mon that resembles a ladybug. It has six legs, that are all wearing gloves.
Bird Wyverns (Japanese é³¥ç«ç¨®) are a class of monsters introduced in the first generation. They are a small to medium sized class that includes Flying Wyverns with slender bodies that are bipedal and, in some cases, either have wings or lack wings. There are two distinct types of Bird Wyverns: Flying Bird Wyverns and Theropod Bird Wyverns.