Most often, the more lymph nodes with cancer, the larger the number assigned. However, for some tumors, the location of the lymph nodes with cancer may determine the âNâ stage category. Metastasis (M). The letter M indicates whether the cancer has metastasized, or spread, to other parts of the body. If the cancer has not spread, it is labeled M0. If the cancer has spread, it is considered M1.
Chondroitin is a molecule that occurs naturally in the body. It is a major component of cartilage, the tough, connective tissue that cushions the joints. Commercial chondroitin comes from natural sources, such as shark and bovine cartilage, or synthetic production.
Chondroitin sulfate and glucosamine are popular supplements used to treat the pain and loss of function associated with osteoarthritis (OA). However, most studies assessing their effectiveness show modest to no improvement compared with placebo in either pain relief or joint damage.