Demyelination is often secondary to an infectious, ischemic, metabolic, or hereditary disorder or to a toxin (eg, alcohol, ethambutol). In primary demyelinating disorders, cause is unknown, but an autoimmune mechanism is suspected because the disorder sometimes follows a viral infection or viral vaccination.
For other uses, see Realm (disambiguation). A realm /ËrÉlm/ is a community or territory over which a sovereign rules; it is commonly used to describe a kingdom or other monarchical or dynastic state. The Old French word reaume, modern French royaume, was the word first adopted in English; the fixed modern spelling does not appear until the beginning of the 17th century.
A realm is an instance of the World of Warcraft (0100) game world. Realms are hosted on physical devices called servers (for this reason, the terms realm and server are often used interchangeably). To play 0100, you must first choose a server (realm) to play on. You then connect to this realm over the Internet. Blizzard has servers in the US, Australia, Europe, China, Brazil and Korea (see Localization).