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Bone marrow, lymph nodes, spleen, tonsils, thymus and Peyer's patches in the small intestine, the liver, and the appendix are all parts of the lymphatic system.
Immune System. Organs of the Immune System: significance of the lymphatic and circulatory systems. Many organs are involved in the immune response like the lymphatic system, bone marrow, the spleen, and the thymus. Bone marrow, the spongy tissue inside of the bone, is the birthing ground for white blood cells. cells mature in the bone marrow, but T cells travel to the thymus to grow. Just like blood travels through veins and arteries, the cells of the immune system have their own transportation system where they perform many functions. This is called the lymphatic system.