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Research suggests that taking L-arginine by mouth or intravenously (by IV) for up to 8 weeks increases blood flow in people with peripheral arterial disease. However, long-term use (up to 6 months) does not improve walking speed or distance in people with peripheral arterial disease.
Recommended dosages for oral L-arginine range from 400 mg to 6,000 mg per day, depending on the reason it is being supplemented. Dosages are typically split into two or three administrations per day. This compound is also used as a pre- or post-workout supplement.