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Prostaglandin F2-alpha(PGF-2 alpha) is a stable prostaglandin that stimulates the contraction of uterine and bronchial smooth muscle and produces vasoconstriction (tightening) in some blood vessels. As a pharmaceutical, the generic name of PGF-2 alpha is dinoprost.rostaglandin F2-alpha(PGF-2 alpha) is a stable prostaglandin that stimulates the contraction of uterine and bronchial smooth muscle and produces vasoconstriction (tightening) in some blood vessels. As a pharmaceutical, the generic name of PGF-2 alpha is dinoprost.
Alpha-2A adrenergic receptor activates Phospholipase C beta 3 or 2 (PLC-beta3 or PLC-beta2) when complex Guanine nucleotide binding protein (G protein) beta and gamma (G-protein beta/gamma) is released from the trimeric complex with G-protein alpha-i family (presumably by G-protein alpha-i2) [ 2 ], [ 3 ].n addition, Alpha-2A and Alpha-2C-1 adrenergic receptors, after activation of c-Src, can activate Shc / GRB2 / SOS without EGFR-transactivation [ 1 ]. Also, all three Alpha-2 adrenergic receptors stimulate v-akt murine thymoma viral oncogene homolog (AKT(PKB)) that is thought to activate ERK2 and ERK1.