Full Definition of TRANSCEND. transitive verb. 1. a: to rise above or go beyond the limits of b: to triumph over the negative or restrictive aspects of: overcome c: to be prior to, beyond, and above (the universe or material existence). 2.
Atherogenesis is the developmental process of atheromatous plaques. It is characterized by a remodeling of arteries leading to subendothelial accumulation of fatty substances called plaques.
Patients with chronic kidney disease (CKD) are at increased risk of atherosclerotic cardiovascular disease and loss of renal parenchyma accelerates atherosclerosis in animal models. Macrophages are central to atherogenesis because they regulate cholesterol traffic and inflammation in the arterial wall.