a distressing emotion aroused by impending danger, evil, pain, etc., whether the threat is real or imagined; the feeling or condition of being afraid. 1  Synonyms: foreboding, apprehension, consternation, dismay, dread, terror, fright, panic, horror, trepidation, qualm. 2  Antonyms: courage, security, calm, intrepidity.
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Reprint Requests: Christopher A. Walsh, MD, PhD, Division of Neurogenetics and Howard Hughes Medical Institute, Department of Neurology, Beth Israel Deaconess Medical Center, NRB 2, 77 Avenue Louis Pasteur, Boston, MA 02115, Tel: 617-667-0813, Fax: 617-667-0815 E-mail: