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Ethnicity â Although Crohnâs disease can affect any ethnic group, Caucasians and people of Eastern European (Ashkenazi) Jewish descent have the highest risk. American Jewish people of European descent are four to five times more likely to develop IBD than the general population.
Sephardi Jews, whose ancestry can be traced to North African and Mediterranean countries, including Spain and Greece, suffer from the same genetic diseases as other populations in these countries. Jews of Sephardi ancestry also have their own set of distinct carrier screening tests based on their country of origin.