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You need to wait a minimum of 18 to 24 hours, until you are in full withdrawal from the hydrocodone. Otherwise, the Suboxone on top of the hydrocodone will produce the worst withdrawal symptoms you have ever felt.
The waiting times will vary depending on the drug of abuse. As a rough guideline, you can expect to have to abstain from: Heroin â 12- 24 hours. Percocet, Vicodin, or Oxycodone â 12-24 hours. Crushed Oxycontin â 12 â 24 hours. Oxycontin 24 hours +. Methadone (must be at low dose) 36 hours (at least)