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This supports the idea that in embryos from wild-type mothers, dpp H~- mutations cause the transformation of dorsal into ven-tral epidermis. If tissue determined to become dorsal epidermis dies in the dpp rim-null embryos, then one should not see ventral or lateral tissue formed in the double-mutant combination.
Background. The term pruritic urticarial papules and plaques of pregnancy (PUPPP) refers to a benign dermatosis that usually arises late in the third trimester of a first pregnancy.The entity previously had been reported as toxemic rash of pregnancy, toxemic erythema of pregnancy, and late-onset prurigo of pregnancy.he prognoses for the affected woman and her newborn are excellent in pruritic urticarial papules and plaques of pregnancy (PUPPP). PUPPP typically resolves within 4-6 weeks, independent of delivery, and the condition does not tend to recur in subsequent pregnancies.