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The most common treatment for CLL is the chemotherapy drug fludarabine. This is given intravenously (through an IV) five days a week once a month, for four to six months. Although the schedule for fludarabine is rather inconvenient, it causes only modest side effects, such as fatigue.
Naltrexone comes in pill form and is taken orally, although it is also available in the form of a 30 day implant known as Vivitrol. The normal way of prescribing naltrexone for the treatment of Alcohol Dependence in the US is to tell people to abstain from alcohol and to take naltrexone daily.