Indications for mitochondrial DNA whole genome sequencing in the following clinical scenarios: 1  Confirmation of a suspected clinical diagnosis of a mitochondrial DNA disorder. 2  Mitochondrial DNA disorders caused by specific point mutation(s) are detected by this testing: 3  Leber hereditary optic neuropathy (LHON).
Androgen antagonists are compounds which inhibit or antagonize the biosynthesis or actions of androgens. Abbot Mcintosh 0 7 years ago Insulin lowers the level of glucose in the blood, whereas glucagon raises it; therefore, glucagon is an antagonist of insulin.
A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist. They are sometimes called blockers; examples include alpha blockers, beta blockers, and calcium channel blockers. In pharmacology, antagonists have affinity but no efficacy for their cognate receptors, and binding will disrupt the interaction and inhibit the function of an agonist or inverse agonist at receptors.