Terminal illness is a disease that cannot be cured or adequately treated and that is reasonably expected to result in the death of the patient within a short period of time.he six-month standard is arbitrary, and best available estimates of longevity may be incorrect. Consequently, though a given patient may properly be considered terminal, this is not a guarantee that the patient will die within six months.
1 Stop metformin if the eGFR is below 30 ml/minute/1.73m2.  Prescribe metformin with caution for those at risk of a sudden deterioration in kidney function and those at risk of eGFR falling below 45ml/minute/1.73m2.
1 Glipizide and metformin should be taken at the same time(s) each day to maintain an even level of the drug in your blood. 2  For the medication to work properly, it must be taken as prescribed. 3  Glipizide and metformin will not work if you stop taking it. It is best to try to take glipizide and metformin with food in order to prevent stomach upset. 2  Glipizide and metformin should be taken at the same time(s) each day to maintain an even level of the drug in your blood.