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When our skin suffers the affects of dehydration, skin problems occur. If you have chronic fatigue syndrome and skin problems, you may be suffering from dehydration. Pain and Joint Swelling. The pain and joint swelling that is so often associated with chronic fatigue syndrome can also be the result of joint dehydration.
Many conditions may cause rapid and continued fluid losses and lead to dehydration: 1  Fever, heat exposure, and too much exercise. 2  Vomiting, diarrhea, and increased urination due to infection. 3  Diseases such as diabetes.  The inability to seek appropriate water and food (as in the case of a disabled person)