On October 23, 2008, TNA aired its first Impact! filmed outside of the Impact Wrestling Zone in Orlando, Florida. It was broadcast from the The Joint in the Hard Rock Hotel and Casino in Las Vegas, Nevada.
Many mutations have no effect at all. These are called silent mutations. But the mutations we hear about most often are the ones that cause disease. Some well-known inherited genetic disorders include cystic fibrosis, sickle cell anemia, Tay-Sachs disease, phenylketonuria and color-blindness, among many others.All of these disorders are caused by the mutation of a single gene.Most inherited genetic diseases are recessive, which means that a person must inherit two copies of the mutated gene to inherit a disorder.ut the mutations we hear about most often are the ones that cause disease. Some well-known inherited genetic disorders include cystic fibrosis, sickle cell anemia, Tay-Sachs disease, phenylketonuria and color-blindness, among many others.
Genetic disorders can be caused by a mutation in one gene (monogenic disorder), by mutations in multiple genes (multifactorial inheritance disorder), by a combination of gene mutations and environmental factors, or by damage to chromosomes (changes in the number or structure of entire chromosomes, the structures that carry genes).