Structure [edit]. The gluteus maximus is the largest of the gluteal muscles and one of the strongest muscles in the human body. It inserts at the iliotibial band and the gluteal tuberosity of the femur.
Causes. Toxic megacolon occurs as a complication of inflammatory bowel disease, such as. and, and infections of the colon. The term toxic means that this complication occurs with infection or inflammation, and is very dangerous.1  ulcerative colitis.2  Crohn's disease.oxic megacolon occurs as a complication of inflammatory bowel disease, such as. and, and infections of the colon. The term toxic means that this complication occurs with infection or inflammation, and is very dangerous. 1  ulcerative colitis.
The management of toxic megacolon is discussed separately. (See Toxic megacolon, section on 'Diagnosis' and Toxic megacolon, section on 'Treatment'.) A multidisciplinary approach is fundamental to the successful management of all patients with severe ulcerative colitis.