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Physiological or biological stress is an organism's response to a stressor such as an environmental condition. Stress is a body's method of reacting to a challenge. According to the stressful event, the body's way to respond to stress is by sympathetic nervous system activation which results in the fight-or-flight response.
Blood is sent to muscles, away from organs, blood pressure rises as vessels tighten, digestion slows, and immune responses weaken as the body prepares for action. This feeling of stress, often referred to as the fight-or-flight response, is directed by the sympathetic nervous system.