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You need to wait a minimum of 18 to 24 hours, until you are in full withdrawal from the hydrocodone. Otherwise, the Suboxone on top of the hydrocodone will produce the worst withdrawal symptoms you have ever felt.
Thereâs no exact science stating that withdrawal will last a specific number of days. The drug itself has a half life of 4 to 6 hours, meaning that hydrocodone stays in your system for less than 24 hours after your last dose. However, just because the drug is clear from your system does not mean that withdrawal is over. Once the drug has finished clearing your system is typically when withdrawal begins.