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The most common form of glycine encephalopathy, called the classical type, appears shortly after birth. Affected infants experience a progressive lack of energy (lethargy), feeding difficulties, weak muscle tone (hypotonia), abnormal jerking movements, and life-threatening problems with breathing.
The deficiency symptoms of Vitamin B6 are seen in the form of fatigue, loss of appetite, emergence of dry skin, hair loss, the appearance of cracks around the lips, insomnia, and swelling in the mouth and tongue.