Combination therapies with agents such as indoleamine 2,3-dioxygenase (IDO) inhibitors may have the potential to synergize with immunotherapeutic approaches to improve immune function against tumor cells.ombination therapies, such as with IDO inhibitors, have the potential to synergize with immunotherapeutic approaches.â Completion of the study is anticipated for November 2017. Alex A. Adjei, MD, PhD, FACP.
The symptoms of a dental cavity depend on the type of cavity and the severity of tooth decay. When a cavity first develops, you likely wonât even know itâs there. When a cavity gets larger, you may experience: toothache.
However, inflammation caused by lupus can also cause a build-up of fluids in the abdominal cavity called ascites (pronounced ah-SAHY-teez). The symptoms you may experience can include severe abdominal pain, tenderness when your belly is touched, nausea and vomiting, fever, and/or lack of bowel movements.