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Research suggests that taking L-arginine by mouth or intravenously (by IV) for up to 8 weeks increases blood flow in people with peripheral arterial disease. However, long-term use (up to 6 months) does not improve walking speed or distance in people with peripheral arterial disease.
L-arginine for erectile dysfunction. Continual dosages of between 3,000 mg to 5,000 mg per day is recommended. In some cases the dosage may be increased to 10,000 mg.*. L-arginine to increase male fertility. If treating poor sperm mobility and/or poor quality sperm, 3,000 mg to 5,000 mg per day is recommended. Within two to three months, fertility should be substantially improved.