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An anticholinergic agent is a substance that blocks the neurotransmitter acetylcholine in the central and the peripheral nervous system.Anticholinergics inhibit parasympathetic nerve impulses by selectively blocking the binding of the neurotransmitter acetylcholine to its receptor in nerve cells.nticholinergic drugs are used to treat a variety of conditions: 1  Gastrointestinal disorders (e.g., gastritis, diarrhea, pylorospasm, diverticulitis, ulcerative colitis, nausea, and vomiting). 2  Genitourinary disorders (e.g., cystitis, urethritis, and prostatitis). 3  Respiratory disorders (e.g., asthma, chronic bronchitis, and chronic obstructive 4  .... S
Noun. 1. anticholinergic-a substance that opposes or blocks the action of acetylcholine. anticholinergic drug. medicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease.