Structure [edit]. The gluteus maximus is the largest of the gluteal muscles and one of the strongest muscles in the human body. It inserts at the iliotibial band and the gluteal tuberosity of the femur.
Causes. Toxic megacolon occurs as a complication of inflammatory bowel disease, such as. and, and infections of the colon. The term toxic means that this complication occurs with infection or inflammation, and is very dangerous.1  ulcerative colitis.2  Crohn's disease.oxic megacolon occurs as a complication of inflammatory bowel disease, such as. and, and infections of the colon. The term toxic means that this complication occurs with infection or inflammation, and is very dangerous. 1  ulcerative colitis.
Common side effects include abdominal pain, constipation, sleepiness, vomiting, and a dry mouth. It may increase the risk of toxic megacolon. Loperamide's safety in pregnancy is unclear, but there is no evidence of harm. It appears to be safe in breastfeeding.