Slemp then bequeathed the house and collection to the Commonwealth of Virginia for a museum. It was officially dedicated as a museum on May 30, 1948. Wax Avenue was named for Don Wax. Don was born April 21, 1927 and grew up in Big Stone Gap.
Bosentan is a dual endothelin receptor antagonist used in the treatment of pulmonary artery hypertension (PAH). It is licensed in the United States, the European Union and other countries by Actelion Pharmaceuticals for the management of PAH under the trade name Tracleer. 1 Medical uses.
Bosentan works by blocking a hormone (a naturally occurring substance), that is found in the blood and lungs in large quantities of the people with pulmonary arterial hypertension. Bosentan helps by increasing the supply of blood to the lungs and reducing the workload of the heart.