Structure [edit]. The gluteus maximus is the largest of the gluteal muscles and one of the strongest muscles in the human body. It inserts at the iliotibial band and the gluteal tuberosity of the femur.
Causes. Toxic megacolon occurs as a complication of inflammatory bowel disease, such as. and, and infections of the colon. The term toxic means that this complication occurs with infection or inflammation, and is very dangerous.1  ulcerative colitis.2  Crohn's disease.oxic megacolon occurs as a complication of inflammatory bowel disease, such as. and, and infections of the colon. The term toxic means that this complication occurs with infection or inflammation, and is very dangerous. 1  ulcerative colitis.
Causes of acquired mega-colon are frequently considered neurologic, metabolic or systemic diseases as well as pharmacologic causes. However, chronic constipation is thought to contribute to the development of mega-colon in children and there are reports of its role in adult pathophysiology. There are no studies demonstrating the prevalence or incidence of mega-colon currently.