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The serotonin transporter gene (5-HTT) is considered as a candidate gene for BPD as multiple lines of evidence have suggested that it plays an important role in suicide, impulsive behaviour, and emotional liability.ompared with healthy controls, patients with BPD showed higher frequencies of the 10 repeat of the VNTR marker and the S-10 haplotype, and fewer 12 repeat and L A -12 haplotype. These results suggest that the serotonin transporter gene may play a role in the aetiology of BPD.
Genetics and Family History. When members of a family pass traits from one generation to another through genes, that process is called heredity. Genetic factors likely play some role in high blood pressure, heart disease, and other related conditions.However, it is also likely that people with a family history of high blood pressure share common environments and other potential factors that increase their risk.he risk for high blood pressure can increase even more when heredity combines with unhealthy lifestyle choices, such as smoking cigarettes and eating an unhealthy diet.