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Research suggests that taking L-arginine by mouth or intravenously (by IV) for up to 8 weeks increases blood flow in people with peripheral arterial disease. However, long-term use (up to 6 months) does not improve walking speed or distance in people with peripheral arterial disease.
LSD's effects generally begin within an hour of taking the drug and last for up to 12 hours. The drug is absorbed from the gastrointestinal tract, and circulated throughout the body and to the brain. It is metabolized in the liver and excreted in the urine about 24 hours after ingestion.