Thatâs what would be happening if the earth was flat. The fact that the sun rises and goes up to a zenith and then goes down into the horizon, shows that the earth is spherical in shape. You can travel a thousand miles around the earth and still see this exact same thing, because the earth is spherical in shape.
Immunoprecipitation (IP) is the technique of precipitating a protein antigen out of solution using an antibody that specifically binds to that particular protein.ne of the major technical hurdles with immunoprecipitation is the great difficulty in generating an antibody that specifically targets a single known protein. To get around this obstacle, many groups will engineer tags onto either the C-or N-terminal end of the protein of interest.
Step 4: Immunoprecipitation. To isolate a specific modified histone, transcription factor or co-factor of interest, ChIP validated antibodies are used to immunoprecipitate and isolate the target from other nuclear components.