Terminal illness is a disease that cannot be cured or adequately treated and that is reasonably expected to result in the death of the patient within a short period of time.he six-month standard is arbitrary, and best available estimates of longevity may be incorrect. Consequently, though a given patient may properly be considered terminal, this is not a guarantee that the patient will die within six months.
1 Stop metformin if the eGFR is below 30 ml/minute/1.73m2.  Prescribe metformin with caution for those at risk of a sudden deterioration in kidney function and those at risk of eGFR falling below 45ml/minute/1.73m2.
Prior to taking metformin (GlucophageÂ®) or metformin ER (Glucophage XRÂ®), you should talk with your healthcare provider if you have: 1  Kidney problems, including kidney failure (renal failure) 2  Liver problems, including liver failure or cirrhosis. 3  Low vitamin B12 levels (pernicious anemia)  Congestive heart failure (CHF)