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Ethnicity â Although Crohnâs disease can affect any ethnic group, Caucasians and people of Eastern European (Ashkenazi) Jewish descent have the highest risk. American Jewish people of European descent are four to five times more likely to develop IBD than the general population.
1 Age: Although colorectal cancer can occur at any age, the chances of developing the disease dramatically increase after the age of 50.  Racial and ethnic background: African Americans have the highest incidence of this disease in the United States. Ashkenazi Jews also have a higher risk of developing colorectal cancer.