When I was first diagnosed with thyroid cancer, I didn't feel any odd lumps or nodules in my neck, but I was suffering from muscle weakness, tiredness and getting constant colds. After a particularly nasty bug I noticed that my lymph nodes never seemed to go down in size.
SIRS is nonspecific and can be caused by ischemia, inflammation, trauma, infection, or several insults combined. Thus, SIRS is not always related to infection. Venn diagram showing overlap of infection, bacteremia, sepsis, systemic inflammatory response syndrome (SIRS), and multiorgan dysfunction.
The introduction of SIRS was intended to define a clinical response to a non-specific insult, either infectious or non-infectious in origin (Table 2). SIRS is defined as 2 or more of the following: SIRS can be incited by ischemia, inflammation, trauma, infection or a combination of several âinsultsâ.