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Because bioidentical hormones are an exact structural replica of endogenous hormones, side effects are rarely observed, and in the event you do experience side effects, talk with your doctorâthe dosage may simply need to be adjusted.
Most of the endogenous causes are a consequence of one or more of the following processes 1  : growth of the adrenal cortex causing the secretion of more cortisol. 2  growth of the anterior pituitary causing a greater secretion of ACTH which stimulate cortisol secretion.