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The serotonin transporter gene (5-HTT) is considered as a candidate gene for BPD as multiple lines of evidence have suggested that it plays an important role in suicide, impulsive behaviour, and emotional liability.ompared with healthy controls, patients with BPD showed higher frequencies of the 10 repeat of the VNTR marker and the S-10 haplotype, and fewer 12 repeat and L A -12 haplotype. These results suggest that the serotonin transporter gene may play a role in the aetiology of BPD.
The Discovery of the lac Operon. In 1961, Francois Jacob and Jacques Monod proposed the operon model of gene regulation in bacteria. The model was based on their study of the genes in E. coli that code for enzymes that affect the breakdown of lactose. Francois Jacob and Jacques Monod. Photo courtesy of Archive Photo. Because of the pioneering work of Jacob and Monod, the lac operon is typically used to illustrate gene regulation in bacteria.