These mutations range from being non-harmful all the way up to causing death. Point Mutations. A point mutation is usually the least harmful of the types of DNA mutations. It is the change of a single nitrogen base in a DNA sequence. Depending on the placement of that nitrogen base in the codon, it can cause no affect to the protein.
1. hoagie-a large sandwich made of a long crusty roll split lengthwise and filled with meats and cheese (and tomato and onion and lettuce and condiments); different names are used in different sections of the United States.
Wawa Hoagiefest is a time for celebration, for joy and for, dare I say, Brotherly Love. If Hoagiesfest cannot unite the city of Philadelphia, what can? The summer celebration of Philly's signature sandwich (not the cheesesteak) begins Monday, June 22. When it does, patrons can grab 10-inch Classic Hoagies for just $4.99, rather than the usual $6.49. Hot, cold, breakfast, whatever -- each variety is part of Hoagiefest. If you have a Wawa Rewards card (essentially, a registered gift card that gives you points) you can get the Hoagiefest deal ahead of time through Sunday, June 21. Lucky you.