All cells require folic acid and it can diffuse easily into human cells. But the vitamin cannot enter bacterial cells and thus bacteria must make their own. The sulfa drugs such as sulfonamides inhibit a critical enzyme--dihydropteroate synthase--in this process. Once the process is stopped, the bacteria can no longer grow.
Sonoma Countyâs natural beauty and moderate temperatures seldom dip below freezing, even in the winter. The areaâs 25- to 30-inch annual rainfall happens primarily from November through April. January â Average high /low. Inland: 58 F (14 C) / 36 F (2 C) Coast: 56 F (13 C) / 35 F (2 C)
Climate for San Francisco County, California. San Francisco County's coldest month is January when the average temperature overnight is 46.4Â°F. In September, the warmest month, the average day time temperature rises to 71.3Â°F. The driest month in San Francisco County is July with 0.04 inches of precipitation, and with 4.72 inches January is the wettest month.