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The serotonin transporter gene (5-HTT) is considered as a candidate gene for BPD as multiple lines of evidence have suggested that it plays an important role in suicide, impulsive behaviour, and emotional liability.ompared with healthy controls, patients with BPD showed higher frequencies of the 10 repeat of the VNTR marker and the S-10 haplotype, and fewer 12 repeat and L A -12 haplotype. These results suggest that the serotonin transporter gene may play a role in the aetiology of BPD.
They found, in addition to the 10 previously known gene regions for CAD, 13 new gene regions. The findings were unexpected. âThe majority reside in gene regions that were not previously suspected in the pathogenesis of CAD,â the researchers write. Genetics play a major role in the development of heart disease.Identifying genes that put people at increased risk could aid in the development of both prevention strategies and new treatments.he discoveries more than double the number of genes previously associated with heart disease, the No. 1 one killer in Western countries and a major health threat in China and other parts of Asia.