Being able to sleep in. All those port days kicked my butt after flying transatlantic last week and hopping from port to port, but it was a good intense. J. Our day started by checking out the Thrill Theater, this is Carnivalâs new 24-seat theater located on deck four. There is a cost to this but in my opinion itâs worth the $7.95 or the unlimited pass for $14.95. The whole area is set up like a box office; you pay and get a pair of 3D glasses and take a seat.
Timely results for microbial bioburden monitoring of in-process cell culture samples are critical to the production process for recombinant proteins and other biopharmaceutical products.
One approach for calculating an average bioburden estimate for the case described above is based upon the Poisson Distribution. The total number of CFU observed for aerobes for a given product batch was zero. The 95% upper confidence limit (UCL) for an observation of zero, using the Poisson Distribution, is 3. For each product batch, with a dilution factor of 3, the calculated average bioburden estimate would be (3/10)*3 or 0.9 CFU. If this approach were applied to all of the results for aerobes, taking into account all three batches of product, the calculation would be (3/30)*3 or 0.3 CFU.