we used experimental animal data to derive a human acute reference dose of 1.33 g/ kg body weight, which corresponds to maximum concentration of TTX in shellï¬sh of 200 g/kg.
Where & Why Nickel is Used. Nickel-containing materials play a major role in our everyday lives â food preparation equipment, mobile phones, medical equipment, transport, buildings, power generation â the list is almost endless.
Historically, this has led to its use for plating metals such as iron and brass, coating chemistry equipment, and manufacturing certain alloys that retain a high silvery polish, such as German silver. About 6% of world nickel production is still used for corrosion-resistant pure-nickel plating. Nickel-plated items are noted for provoking nickel allergy. Nickel has been widely used in coins, though its rising price has led to some replacement with cheaper metals in recent years.