Exhaust system affects fuel efficiency. If you notice you have to fill up your gas tank more often than normal, have your exhaust system checked out by a muffler repair shop. Similar to the vibrations, increased fuel use is a sign something is wrong with your car. When the exhaust leaks, your engine works harder.
Temporal summation is the linear addition of graded potentials that overlap in time; that is, a second potential arrives before the first one from that source has finished. Spatial summation occurs when there is simultaneous arrival of graded potentials originating from more than one synaptic input. Summation occurs at the trigger zone. Typically a multipolar neuron has many active synapses at a given time, with multiple potentials being produced at each.
Visceral hemangiosarcoma most commonly occurs in the dog's spleen and the right atrium of the heart. The characteristics of this type of hemangiosarcoma is that it is locally invasive and prone to spread to other locations. Many of the warning signs of visceral hemangiosarcoma are non-specific, for example, the dog may have: