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nodule - (mineralogy) a small rounded lump of mineral substance (usually harder than the surrounding rock or sediment) mineralogy - the branch of geology that studies minerals: their structure and properties and the ways of distinguishing them.
A thyroid nodule is an unusual growth (lump) of thyroid cells in the thyroid gland. The thyroid is part of the endocrine system, which is made up of glands that secrete various hormones into the bloodstream.