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But the bottom line is that long-term, heavy cannabis use may impair the dopaminergic system, which could have a variety of negative effects on learning and behavior.. You might also like: Young Marijuana Users Show a Unique Response to Social Rejection, Study Finds.
Since we know that marijuana can disrupt memory, the likely target in the brain is the hippocampus, the region most linked to memory formation. When cannabinoid receptors in the hippocampus are activated, they interfere with a cellular process called long term potentiation, a long-lasting booster