Actinic keratoses that develop on the lips are referred to as actinic cheilitis. The clinical appearance of an actinic keratosis is that of a small (several millimeters), red scaly papule or plaque, with induration and thickening of the epidermis.
1 Location: Ideally, the probe should be in close proximity to the forward or reverse primer, but should not overlap with a primer-binding site on the same strand. 2  Probes can be designed to bind to either strand of the target. 3  Melting temperature (Tm): Preferably, probes should have a Tm 6â8Â°C higher than the primers.
Transverse probes, most often rectangular in shape, measure fields normal to their stem width. They are useful for most general purpose field measurements and are essential for work in magnet gaps. Several standard stem lengths and diameters are available, as well as flexible, cryogenic, tangential and brass stem probes. Tangential probes are transverse probes designed to measure fields parallel to and near a surface. The active area is very close to the stem tip.