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How to Take PRISTIQ. Most people start with a once-daily 50-mg dose of PRISTIQ (taken with or without food). Your doctor may keep you on your starting dose throughout your treatment.Talk to your doctor about any health conditions you may have, as your dose might be affected.PRISTIQ should be taken at the same time each day and always swallowed whole, since the tablets are time released.our doctor may keep you on your starting dose throughout your treatment. Talk to your doctor about any health conditions you may have, as your dose might be affected. PRISTIQ should be taken at the same time each day and always swallowed whole, since the tablets are time released.
While taking Pristiq 100mg, I lost my sex drive and ability to ejaculate. Buspar completely brought back my libido/sex drive when increased from 15mg twice a day to 25mg twice a day. No more orgasm/ejaculation problems. Feel like a teenager all over again. I can now have sex everyday without any problems.