In contrast to proteins, which can have either a net positive or net negative charge, nucleic acids have a consistent negative charge imparted by their phosphate backbone, and migrate toward the anode. Proteins and nucleic acids are electrophoresed within a matrix or gel.
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Multinational Design Evaluation Programme (MDEP) MDEP was established in 2006 as a multinational initiative to develop innovative approaches to leverage the resources and knowledge of the national regulatory authorities that are currently or will be tasked with the review of new nuclear power reactor designs.