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Primary Pathogens are the microorganisms that cause diseases in healthy individual. Opportunistic Pathogens are the microorganisms that are ordinarily in contact with the host and cause disease when the host's resistance is low. Primary Pathogens are the microorganisms that cause diseases in healthy individual.
In the bacterial pathogens, the most variable structures are those expressed in the cell surface. LPS is one of the principal antigenic structures of cell surface of gram-negative bacteria. A great variability in LPS has been demonstrated and principally in O antigen of gram-negative bacteria.