Phosphorylation of signal transduction molecules is a major activating event that leads to dramatic changes in tumor growth. Some TKs, such as epidermal growth factor receptor (EGFR)-TK, can autophosphorylate when activated, as well as phosphorylating other signaling molecules [2].
Risk indexes Definition: Categories of risk used to calculate fundamental beta, including (1) market variability, (2) earnings variability, (3) low valuation, (4) immaturity and smallness, (5) growth orientation, and (6) financial risk.
University of Warwick Risk Initiative Briefing. Managing Risk and Innovation: the Challenge for Smaller Businesses. Successful innovation is in large measure an issue of identifying and controlling risk. The. smaller the business, the more likely it is that survival will depend on effective risk. management. Small and medium sized enterprises (SMEs) are caught in a double bind. As competitive. pressures mount and customers press for higher quality standards, tighter cost control and.