By Carolyn L. Driedger and William E. Scott, USGS -- Republished from USGS fact sheet 2008-3062. 1  Mount Rainier: The flat floor of the Puyallup River valley near Orting, Washington, is formed by deposits of the 500-year-old Electron lahar, which surged down from Mount Rainier (in background).
Substitution mutation. Definition. A type of point mutation in which a single nucleotide is substituted with (or exchanged for) a different nucleotide that may result in an altered sequence of amino acid during translation, which may render the newly synthesized protein ineffective.Supplement.n transversion, purine is substituted with pyrimidine or a pyrimidine with a purine. See also: point mutation. Please contribute to this project, if you have more information about this term feel free to edit this page. This page was last modified on 16 October 2008, at 00:53.This page has been accessed 109,894 times.
Mutations commonly are substitutions, in which a single nucleotide is changed into a different nucleotide. Other mutations result in the loss (deletion) or addition (insertion) of one or more nucleotides. These insertions or deletions can range from one to tens of thousands of nucleotides.ometimes the template strand can loop out and form a secondary structure that the DNA polymerase does not read. In this case, a deletion in the nascent strand will result. The ability of intercalating agents to increase the frequency of such deletions is illustrated in Fig. 7.10.B. (see below).