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L-arginine has unpredictable effects on insulin and cholesterol-lowering agents. L-arginine may increase the effects of isosorbide mononitrate and other nitric oxide donors, such as glyceryl trinitrate and sodium nitroprusside. Side Effects. L-arginine has few reported adverse reactions. Nausea and diarrhea have been reported infrequently.
The scientistsâ conclusion was that taking L-Arginine can help to prevent dangerous circulatory disturbances caused by blood sugar levels. This conclusion was also drawn for diabetes type 2 patients, as diabetesâ effects on blood vessels and metabolism are the same, even if the two types have different causes.