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Most people who have piriformis syndrome get better with treatment and lifestyle changes. Failure to treat this condition can lead to permanent nerve damage, so be sure to follow your doctorâs instructions.
The piriformis is a muscle that lies deep within the buttocks, covered by the gluteal muscles. It originates on the front surface of the sacrum, passes through the greater sciatic foramen, and inserts into the greater trochanter of the femur (see figure 1).hile athletes are usually symptomatic in only one leg, the pain-free leg should be treated as well. In the New York study, investigators determined the most common causes of piriformis syndrome are overuse (43% of 876 patients) and trauma (18% of 892 patients).