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- this hormone targets the kidneys, hypothalamus, and adrenal gland function of atrial natriuretic peptide increase water and salt loss at kidneys; decrease thirst, suppress secretion of ADH and aldosterone what does the thymus release? thymosins, which targets lymphocytes
1 The hormones ADH (antidiuretic hormone, also known as vasopressin) and aldosterone play a major role in this.  If the body is becoming fluid-deficient, this will be sensed by osmoreceptors, which results in increased secretion of ADH, causing fluid to be retained by the kidneys and urine output to be reduced.