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Long-term treatment with ibuprofen at a dose of 1200 mg/day does not increase the risk of renal impairment in elderly people (Griffin et al, 2000). Ibuprofen is associated with a low risk of renal toxicity in overdose (Jenkinson et al, 1988; Volans and Fitzpatrick, 1999).
Ibuprofen is used to reduce fever and treat pain or inflammation caused by many conditions such as headache, toothache, back pain, arthritis, menstrual cramps, or minor injury. The dose of ibuprofen can range from 200 mg every 4 to 6 hours up to 800 mg every 6 hours. The maximum daily dose anyone should ever take is 800 mg every 6 hours or a total of 3200 mg per day. However, anything over the recommended over-the-counter dose of 200 mg should only be taken on the advise of your doctor.