Another important site of histamine storage and release is the enterochromaffin-like (ECL) cell of the stomach. The most important pathophysiologic mechanism of mast cell and basophil histamine release is immunologic. These cells, if sensitized by IgE antibodies attached to their membranes, degranulate when exposed to the appropriate antigen.
Report Abuse. There are 4 seasons in America: Spring, Summer, Fall (Autumn), and Winter. In the Springtime, (February-May) the first season in the year, it is mildly warm and sometimes chilly. In the Summertime, (June-August) the second season of the year, it is hot and sunny.
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