22q11.2 deletion syndrome is caused by the deletion of a small section of chromosome 22. It results in a cleft palate, heart defects, autoimmune disorders, and more. The symptoms vary wildly and can be accompanied by learning disabilities and mental illness. Cystic fibrosis is caused by a point deletion.
The melody of Happy Birthday to You comes from the song  Good Morning to All , which has been attributed to American siblings Patty Hill and Mildred J. Hill in 1893, although the claim that the sisters composed the tune is disputed.
Happy is a song written, produced and performed by American singer and producer Pharrell Williams, from the Despicable Me 2 soundtrack album. It also served as the lead single from Williams' second studio album, Girl (2014). It was first released on November 21, 2013, alongside a long-form music video.