Changes with Age. In most cases, a person's normal respiratory rate will change with age; younger adults, children, and babies will typically have faster respiratory rates, because as people age, their breathing usually slows down.
Modic changes are pathological changes in the bones of the spine, the vertebrae. These changes are situated in both the body of the vertebrae and in the end plate of the neighboring disc.
Modic type I changes are seen much more frequently in patients with low back pain (46%) compared to asymptomatic general population (6%) 1. They are believed to be the result of fissuring of the endplates with the development of vascular granulation tissue adjacent to the endplates, resulting in bone marrow oedema 2.