a recognition that genres are situated within discourse communities, wherein the beliefs and naming practices of members have relevance an emphasis on communicative purpose and social action an interest in generic structure (and its rationale)
Because of the potential implication of circulation disorders, darkened skin around the ankles that is not immediately explainable by simple environmental factors should be promptly called to the attention of a medical doctor for appropriate diagnosis and treatment.
Excess homogentisic acid and related compounds are deposited in connective tissues, which causes cartilage and skin to darken. Over time, a buildup of this substance in the joints leads to arthritis. Homogentisic acid is also excreted in urine, making the urine turn dark when exposed to air.