22q11.2 deletion syndrome is caused by the deletion of a small section of chromosome 22. It results in a cleft palate, heart defects, autoimmune disorders, and more. The symptoms vary wildly and can be accompanied by learning disabilities and mental illness. Cystic fibrosis is caused by a point deletion.
The melody of Happy Birthday to You comes from the song  Good Morning to All , which has been attributed to American siblings Patty Hill and Mildred J. Hill in 1893, although the claim that the sisters composed the tune is disputed.
 Birthday  is a song by American recording artist Selena Gomez for her solo debut album Stars Dance (2013). It was written and produced by Mike Del Rio, with additional writing by Crista Russo and Jacob Kasher Hindlin. Matt Beckley also provided additional vocal production for the song.