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Side Effects of L-arginine Hydrochloride For most people, taking L-arginine hydrochloride is thought to be relatively safe. Possible side effects of using L-arginine HCL capsules or powder include bloating, diarrhea, abdominal pain, gout, abnormalities in blood circulation, low blood pressure, inflammation of the lungs and airways, allergies and worsening of asthma symptoms. High-doses of L-arginine may be potentially fatal in children.
L-arginine isn't recommended after a heart attack due to concerns that the supplement might increase the risk of death. L-arginine can worsen allergies or asthma. Use the supplement with caution if you have these conditions. Be careful about taking L-arginine if you've had cold sores or genital herpes.