Actinic keratoses that develop on the lips are referred to as actinic cheilitis. The clinical appearance of an actinic keratosis is that of a small (several millimeters), red scaly papule or plaque, with induration and thickening of the epidermis.
1 Location: Ideally, the probe should be in close proximity to the forward or reverse primer, but should not overlap with a primer-binding site on the same strand. 2  Probes can be designed to bind to either strand of the target. 3  Melting temperature (Tm): Preferably, probes should have a Tm 6â8Â°C higher than the primers.
It could take as long as 120 days. Most space probes do not accelerate constantly, but use planetary gravity effects to speed up or slow down, which involves long, complex orbits taking a year or more. In this case, a spacecraft actually has to decelerate from the Earth's orbital speed (about 107,000 km/hr) to reach Venus or Mercury.