Changes with Age. In most cases, a person's normal respiratory rate will change with age; younger adults, children, and babies will typically have faster respiratory rates, because as people age, their breathing usually slows down.
Modic changes are pathological changes in the bones of the spine, the vertebrae. These changes are situated in both the body of the vertebrae and in the end plate of the neighboring disc.
The minimal detectable change (MDC) and the minimal clinically important changes (MCIC) have been explored for nonspecific low back pain patients and are similar across different cultural settings. No data on MDC and MCIC for pain severity are available for neck pain patients.