Another important site of histamine storage and release is the enterochromaffin-like (ECL) cell of the stomach. The most important pathophysiologic mechanism of mast cell and basophil histamine release is immunologic. These cells, if sensitized by IgE antibodies attached to their membranes, degranulate when exposed to the appropriate antigen.
Report Abuse. There are 4 seasons in America: Spring, Summer, Fall (Autumn), and Winter. In the Springtime, (February-May) the first season in the year, it is mildly warm and sometimes chilly. In the Summertime, (June-August) the second season of the year, it is hot and sunny.
This is why we have seasons. How exactly do seasons work? In most cultures, including all western countries, the year is commonly divided into four seasons: Spring; Summer; Fall or Autumn; Winter; Since the year has 12 months, each season lasts about three months. However, the dates when the seasons begin and end vary depending on whom you ask. Two methods are most commonly used to define the dates of the seasons: the astronomical definition and the meteorological definition.