In 1841 and 1842, the first two years of the Trail's use by emigrant parties, the overland route ended at Fort Walla Walla, at the mouth of the Walla Walla River. From there, emigrants rafted their wagons down the Columbia River to the Willamette River Valley.
I have been an insulin dependent diabetic for 20 years. I had my first ever cortison injection for a worn out knee. For 5 days after the injection my blood sugar levels ran between 450 and 600. No matter how much fast acting insulin I took, it would not go down.
A normal response to Dexamethasone is still suppression of Cortisol to less than 50 nmol/L. Synacthen tests: normal response is cortisol above 420 nmol/L on 30-minute sample. Consider pituitary failure if low baseline cortisol, especially if below 170 nmol/L in morning.