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Patients with acute brachial plexus neuritis are often misdiagnosed as having cervical radiculopathy. Acute brachial plexus neuritis is an uncommon disorder characterized by severe shoulder and upper arm pain followed by marked upper arm weakness. The temporal profile of pain preceding weakness is important in establishing a prompt diagnosis and differentiating acute brachial plexus neuritis from cervical radiculopathy.
Muscle strain. There are several muscles of the chest and arms that could cause armpit pain from overuse or injury. The pectoralis major is a large chest muscle that runs up into the shoulder. It can be injured playing sports or lifting weights.