When incompatible blood is given, antibodies and complement in the recipient plasma attack the antigens on the donor RBC. Hemolysis ensues The antigen-antibody complex activate the Hageman factor (factor XII), which acts on the kinin system to produce bradykinin
Three years. The month and year of expiration is reflected on the individual packets and the outside of the box directly under the âDrug Factsâ section. Due to the high demand, all of our saline has been purchased long before it approaches expiration. more.
There will always be an expiration date on the package and this typically will be around 2 years. Once the Botox has been mixed with saline, it is generally recommended to use it within 4 hours. However it is thought that it will probably maintain its potency for up to about 2 weeks following mixing.