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Causes. Ischemic cardiomyopathy is weakness in the muscle of the heart due to coronary artery disease. Individuals with ischemic cardiomyopathy typically have a history of myocardial infarction (heart attack). Nonischemic cardiomyopathy is weakness in the muscle of the heart that is not due to coronary artery disease.ndividuals with ischemic cardiomyopathy typically have a history of myocardial infarction (heart attack). Nonischemic cardiomyopathy is weakness in the muscle of the heart that is not due to coronary artery disease.
Ischemic heart disease, also known as myocardial ischemia, is a condition of the heart where the heart muscles are damaged or do not work as efficiently due to a reduced blood supply to the heart.The decreased blood flow is most often caused by narrowing of the coronary arteries, a condition called atherosclerosis.he symptoms of ischemic heart disease. The most serious symptom is chest pain, which can indicate a heart attack (also known as cardiac arrest). This is felt as a tightening or weighing down of the chest and upper body parts including the neck, jaws, and shoulders.