Definition of legend for English Language Learners. : 1  a story from the past that is believed by many people but cannot be proved to be true. : 2  a famous or important person who is known for doing something extremely well. : 3  a list that explains the symbols on a map.
glaÂ·cis. n. pl. glacis. 1. a. A gentle slope; an incline. b. A slope extending down from a fortification.
Fabry disease is a rare genetic disease caused by mutations in the GLA gene, which result in a deficiency of a metabolic enzyme, alpha-galactosidase A. When this enzyme is absent or in low abundance, glycosphingolipid (a type of fat) accumulates within the blood vessels and a number of tissues and organs, leading to impaired function.