MAPK/ERK pathway. The MAPK/ERK pathway (also known as the Ras-Raf-MEK-ERK pathway) is a chain of proteins in the cell that communicates a signal from a receptor on the surface of the cell to the DNA in the nucleus of the cell.
Acclimatization or acclimatisation (also called acclimation or acclimatation) is the process in which an individual organism adjusts to a change in its environment (such as a change in altitude, temperature, humidity, photoperiod, or pH), allowing it to maintain performance across a range of environmental conditions.
When a person travels to a location that is greater than 8,000 feet, they must do so at a speed that allows their body to acclimatize to certain changes, such as decreased air pressure, low humidity, and greater exposure to ultraviolet rays. Typically, full acclimatization can take as much as five days. If a person does not fully acclimatize to the higher altitude, it may cause a condition known as altitude sickness. The three forms of altitude sickness are acute mountain sickness, high altitude pulmonary edema, and high-altitude cerebral edema.