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Sudafed (pseudoephedrine) and other decongestants can cause erectile dysfunction (ED) in some men. If you are having trouble getting or maintaining an erection while taking Sudafed, your doctor or pharmacist can recommend a different medication.
NPLEx Answers Site. In 2005 Kentucky and dozens of other states passed laws restricting the sale of products containing pseudoephedrine (PSE), the key ingredient for meth production. These laws closely followed similar legislation enacted in Oklahoma in 2004. States that restricted PSE began seeing immediate declines in meth-lab responses.