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How to Take PRISTIQ. Most people start with a once-daily 50-mg dose of PRISTIQ (taken with or without food). Your doctor may keep you on your starting dose throughout your treatment.Talk to your doctor about any health conditions you may have, as your dose might be affected.PRISTIQ should be taken at the same time each day and always swallowed whole, since the tablets are time released.our doctor may keep you on your starting dose throughout your treatment. Talk to your doctor about any health conditions you may have, as your dose might be affected. PRISTIQ should be taken at the same time each day and always swallowed whole, since the tablets are time released.
I am also seeing a lessening of the sexual side effects. I did not have any of the sweating or dry mouth, but that may be because I have been on an SNRI for awhile and my body was used to it. Read More. My only complaint with Pristiq is that at 100Mgs a day dosage I have sexual side effects from it.I am male and it has reduced my sex drive by about 50% which I hate. The side effects of stopping Pristiq are much the same as with Effexor.They can be rough as I once ran out for two days and had withdrawls.ead More. My only complaint with Pristiq is that at 100Mgs a day dosage I have sexual side effects from it. I am male and it has reduced my sex drive by about 50% which I hate. The side effects of stopping Pristiq are much the same as with Effexor. They can be rough as I once ran out for two days and had withdrawls.