1 A person may or may not have any symptoms previously, but all of the sudden a plaque ruptures, triggering a chain of events and a sudden heart attack.  The other is a more gradual progression of coronary disease. In these patients, an artery is getting narrower over time.
Knee pain at night causes. Common causes of knee pain at night include sprains and strains, anterior knee pain, menisci or cartilage damage, osteoarthritis tendonitis, bursitis, torn ligaments or tendons, bleeding into the joint, Osgood Shatlerâs disease, gout, septic arthritis, overuse, and obesity.
Leg pain can occur in the foot, ankle, knee, behind the knee, thigh, down the back of the leg, or in any part of the leg. It can occur at night, while lying down, or while running or exercising, depending upon the cause. Depending on the cause, leg pain can occur in one leg only or in both legs. Typically, the leg pain is a result of tissue inflammation that is caused by injury or disease. Either injury or chronic disease can cause inflammation to any of the tissues of the leg and lead to leg pain. Since the leg contains a number of different structures and tissue types, a wide variety of conditions and injuries can cause leg pain. Depending on the cause of the pain, other symptoms, like. weakness, numbness, throbbing, cramps, aching, or; a tingling sensation, may accompany leg pain.