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Sudafed (pseudoephedrine) and other decongestants can cause erectile dysfunction (ED) in some men. If you are having trouble getting or maintaining an erection while taking Sudafed, your doctor or pharmacist can recommend a different medication.
Best Answer: Pseudoephedrine is typically used in non-drowsy medicines, and the Sudafed with this ingredient is supposed to not put you to sleep. BUT everyone reacts differently and even medicine designed to be non-drowsy can adversely affect you.