1 A person may or may not have any symptoms previously, but all of the sudden a plaque ruptures, triggering a chain of events and a sudden heart attack.  The other is a more gradual progression of coronary disease. In these patients, an artery is getting narrower over time.
Knee pain at night causes. Common causes of knee pain at night include sprains and strains, anterior knee pain, menisci or cartilage damage, osteoarthritis tendonitis, bursitis, torn ligaments or tendons, bleeding into the joint, Osgood Shatlerâs disease, gout, septic arthritis, overuse, and obesity.
As atherosclerosis progresses and blockage becomes more severe, pain may occur in the feet even when at rest. This pain, known as rest pain, occurs because the arteries of the leg can no longer deliver adequate blood flow to the feet, even at rest. Rest pain generally worsens when the legs are elevated, such as when lying in bed at night.