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For example, a human cell has 46 chromosomes. In the karyotype, 23 pairs of chromosomes will be shown (23 x 2 = 46). A karyotype can show different types of mutations, depending on which chromosome it affects.For example, Down Syndrome is a trisomy in chromosome 21, so there will be THREE instead of two chromosome 21s. You can research more mutations shown by chromosomes in a karyotype.or example, a human cell has 46 chromosomes. In the karyotype, 23 pairs of chromosomes will be shown (23 x 2 = 46). A karyotype can show different types of mutations, depending on which chromosome it affects.
Make a Karyotype. A karyotype is an organized profile of a person's chromosomes. Two chromosomes specify gender  XX for female and XY for male. The rest are arranged in pairs, numbered 1 through 22, from largest to smallest. This arrangement helps scientists quickly identify chromosomal alterations that may result in a genetic disorder.