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- this hormone targets the kidneys, hypothalamus, and adrenal gland function of atrial natriuretic peptide increase water and salt loss at kidneys; decrease thirst, suppress secretion of ADH and aldosterone what does the thymus release? thymosins, which targets lymphocytes
1 If the body is becoming fluid-deficient, this will be sensed by osmoreceptors, which results in increased secretion of ADH, causing fluid to be retained by the kidneys and urine output to be reduced.  The hormones ADH (Anti-diuretic Hormone, also known as vasopressin) and aldosterone play a major role in this.