When incompatible blood is given, antibodies and complement in the recipient plasma attack the antigens on the donor RBC. Hemolysis ensues The antigen-antibody complex activate the Hageman factor (factor XII), which acts on the kinin system to produce bradykinin
Three years. The month and year of expiration is reflected on the individual packets and the outside of the box directly under the âDrug Factsâ section. Due to the high demand, all of our saline has been purchased long before it approaches expiration. more.
No. It does not really expire. Over time some substances tend to degrade, separate, or change due to many different conditions. Some things are very stable, however, like salt. The only thing an expiration date really means is that the packager will not vouch for its quality after that date.