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Malignant hypertension is a serious condition caused by very high blood pressure. It can quickly cause serious damage to eyes, kidneys and brain. Some of the changes can be reversed by treatment but some permanent damage may occur. Malignant means bad or evil.
This can be caused by: 1  Increased hydrostatic pressure as a result of congestive heart failure (CHF), overhydration, or a tumor within the chest cavity. 2  Hypoalbuminemia (low levels of protein in the blood) secondary to liver kidney or intestinal disease. 3  Changes in permeability of blood vessels (i.e. they become leaky )