In project management, a change order is a component of the change management process whereby changes in the Scope of Work agreed to by the Owner, Contractor and Architect/Engineer are implemented.
Oligodendrocytes is located in the central nervous system. It is a type of neuroglia (group of cells that support neurons). Its function is to produce myelin sheaths around CNS nerve fibers. Oligodendrocytes are types of cells that make up the supportive or glial tissue of the brain.ligodendrocytes are found in the central nervous system, primarily in the brain but also in smaller numbers in the spinal cord. Oligodendrocytes are small, rounded cells with one or a few processes, or extensions.
Each oligodendrocyte can supply myelin for several axons and each axon can be supplied by several oligodendrocytes. Oligodendrocytes wrap the myelin around the axons in thin sheets like rolled up paper. Schwann cells, another kind of glial cell, makes a slightly different kind of myelin in the peripheral nervous system.When parts of the myelin sheath is lost, oligodendrocytes attempt to replace it. In acute MS lesions, typical of very aggressive disease courses, oligodendrocytes are found in large numbers and there is evidence of abortive remyelination-probably the new myelin is being destroyed faster than the oligodendrocytes can lay it down.