Phosphorylation of signal transduction molecules is a major activating event that leads to dramatic changes in tumor growth. Some TKs, such as epidermal growth factor receptor (EGFR)-TK, can autophosphorylate when activated, as well as phosphorylating other signaling molecules [2].
Risk indexes Definition: Categories of risk used to calculate fundamental beta, including (1) market variability, (2) earnings variability, (3) low valuation, (4) immaturity and smallness, (5) growth orientation, and (6) financial risk.
Called the Hematuria Risk Index, the model assigns points for specific cancer risk factors. Higher risk factors, such as a history of gross hematuria and patient age of 50 years or over, are assigned four points, while lower risk factors, such as a history of smoking, and patients who are male, are given one point.