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Signs of physical and emotional exhaustion: 1  Chronic fatigue. 2  Insomnia. 3  Forgetfulness/impaired concentration and attention. 4  Physical symptoms. 5  Increased illness. 6  Loss of appetite. 7  Anxiety. 8  Depression. 9  Anger.
Other associated symptoms with fatigue include: 1  weight loss, 2  chest pain and shortness of breath, 3  vomiting and diarrhea, 4  fevers and chills, 5  muscle weakness or pain, and/or.  anxiety and depression.