Tweet on Twitter. 1. Mucus from cystic fibrosis patients had a rope-like structure and high elasticity due to chemical cross-links between mucin proteins. 2. A compound designed to break down mucin cross-links was more effective in vitro than a currently available drug and was safe in mice.Evidence Rating Level: 2 (Good).Study Rundown: In lung diseases such as cystic fibrosis, pathological mucus is highly elastic and thus cannot be readily cleared from the airway. In this study, researchers identified the cause of the pathology and designed a chemical compound to improve mucus biophysical properties.weet on Twitter. 1. Mucus from cystic fibrosis patients had a rope-like structure and high elasticity due to chemical cross-links between mucin proteins. 2. A compound designed to break down mucin cross-links was more effective in vitro than a currently available drug and was safe in mice.
When a structural problem is suspected, a variety of imaging tests can be used to evaluate the kidneys. A sample of kidney tissue, a biopsy, is sometimes helpful in diagnosing the specific cause of a problem. Tests commonly used for screening and diagnosis. The National Kidney Foundation (NKF) and the National Kidney Disease Education Program (NKEDP) recommend that people who are at high risk be screened for kidney disease to detect it in its earliest stages.
IVP may be performed at the same time as a computed tomography (CT) scan of the kidneys (also called nephrotomography). This test, like the IVP, is performed after contrast dye has been injected, but unlike a standard X-ray, provides images of layers or slices of the kidney. As newer technologies are developed, other procedures such as CT, MRI, and ultrasound (high-frequency sound waves) are often used instead of IVP.