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Medicines and Drugs that can Destroy Your Teeth. There are some medications, such as the antibiotics tetracycline, that may result in internal staining of the teeth. The production and use of methamphetamines, which is a strong stimulant drug, is an increasing problem in the United States.
As dry mouth is also a common side effect of other stimulants, which are not known to contribute severe tooth decay, many researchers suggest that methamphetamine associated tooth decay is more due to users' other choices.