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Side Effects of L-arginine Hydrochloride For most people, taking L-arginine hydrochloride is thought to be relatively safe. Possible side effects of using L-arginine HCL capsules or powder include bloating, diarrhea, abdominal pain, gout, abnormalities in blood circulation, low blood pressure, inflammation of the lungs and airways, allergies and worsening of asthma symptoms. High-doses of L-arginine may be potentially fatal in children.
Medline Plus also notes that L-arginine is possibly effective for the chest pain associated with coronary artery disease -- although it does not improve heart disease itself -- erectile dysfunction, cramping in the legs associated with atherosclerosis, heart attack and increased gestational blood pressure.nce in the body, L-arginine is converted into another chemical, known as nitric oxide, which can improve blood flow and stimulate the release of certain hormones, including insulin and growth hormone.