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- this hormone targets the kidneys, hypothalamus, and adrenal gland function of atrial natriuretic peptide increase water and salt loss at kidneys; decrease thirst, suppress secretion of ADH and aldosterone what does the thymus release? thymosins, which targets lymphocytes
The system exerts its influence via release or inhibition of vasopressin (antidiuretic hormone, ADH) which acts on the kidney to decrease water excretion. Deficiency of ADH is usually due to hypothalamic-neurohypophyseal lesions (central diabetes insipidus) or insensitivity of the kidney to ADH (nephrogenic diabetes insipidus). These patients, if untreated, have the predictable result of dehydration, hyperosmolality, hypovolemia, and eventual death in severe cases.