Changes with Age. In most cases, a person's normal respiratory rate will change with age; younger adults, children, and babies will typically have faster respiratory rates, because as people age, their breathing usually slows down.
Modic changes are pathological changes in the bones of the spine, the vertebrae. These changes are situated in both the body of the vertebrae and in the end plate of the neighboring disc.
Eventually, the term MODS was proposed as a more appropriate description. MODS is defined as a clinical syndrome characterized by the development of progressive and potentially reversible physiologic dysfunction in 2 or more organs or organ systems that is induced by a variety of acute insults, including sepsis.