Phosphorylation of signal transduction molecules is a major activating event that leads to dramatic changes in tumor growth. Some TKs, such as epidermal growth factor receptor (EGFR)-TK, can autophosphorylate when activated, as well as phosphorylating other signaling molecules [2].
Risk indexes Definition: Categories of risk used to calculate fundamental beta, including (1) market variability, (2) earnings variability, (3) low valuation, (4) immaturity and smallness, (5) growth orientation, and (6) financial risk.
Risk Score is used to rank a risk's priority relative to the other identified risks. The risk with the highest risk score is ranked first in priority, the risk with the next highest risk score is ranked second in priority and so forth. The closer the risk score is to one the higher the priority; the closer a risk score is to zero the lesser the priority.