anything done or to be done; anything requiring action or effort; business; concern: an affair of great importance. 2. affairs, matters of commercial or public interest or concern; the transactions of public or private business or finance:
Hyperlactatemia is defined as a persistent, mild to moderate (2-4 mmol/L) increase in blood lactate concentration without metabolic acidosis, whereas lactic acidosis is characterized by persistently increased blood lactate levels (usually >5 mmol/L) in association with metabolic acidosis.
Has any of the following laboratory abnormalities when screened: Serum haptoglobin below the lower limit of normal; Lactate dehydrogenase (LDH) > 300 U/L; Low-Density Lipoprotein (LDL) > 190 mg/dL; Fasting (8 hours, water only) triglyceride level > 300 mg/dL; Serum phospholipid level > 500 mg/dL.