By Carolyn L. Driedger and William E. Scott, USGS -- Republished from USGS fact sheet 2008-3062. 1  Mount Rainier: The flat floor of the Puyallup River valley near Orting, Washington, is formed by deposits of the 500-year-old Electron lahar, which surged down from Mount Rainier (in background).
Substitution mutation. Definition. A type of point mutation in which a single nucleotide is substituted with (or exchanged for) a different nucleotide that may result in an altered sequence of amino acid during translation, which may render the newly synthesized protein ineffective.Supplement.n transversion, purine is substituted with pyrimidine or a pyrimidine with a purine. See also: point mutation. Please contribute to this project, if you have more information about this term feel free to edit this page. This page was last modified on 16 October 2008, at 00:53.This page has been accessed 109,894 times.
Thus the amino acid sequence encoded by the gene is not changed and the mutation is said to be silent. Missence: When base substitution results in the generation of a codon that specifies a different amino acid and hence leads to a different polypeptide sequence.Depending on the type of amino acid substitution the missense mutation is either conservative or nonconservative.ypes of Mutations. There are three types of DNA Mutations: base substitutions, deletions and insertions. 1. Base Substitutions. Transition: this occurs when a purine is substituted with another purine or when a pyrimidine is substituted with another pyrimidine.