1 A person may or may not have any symptoms previously, but all of the sudden a plaque ruptures, triggering a chain of events and a sudden heart attack.  The other is a more gradual progression of coronary disease. In these patients, an artery is getting narrower over time.
Knee pain at night causes. Common causes of knee pain at night include sprains and strains, anterior knee pain, menisci or cartilage damage, osteoarthritis tendonitis, bursitis, torn ligaments or tendons, bleeding into the joint, Osgood Shatlerâs disease, gout, septic arthritis, overuse, and obesity.
The risk of ankle cramps increases with age. An injury to the ankle can also cause cramping at night. People with metabolic problems experience ankle and leg cramps as well, according to Mayo Clinic.