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Medicines and Drugs that can Destroy Your Teeth. There are some medications, such as the antibiotics tetracycline, that may result in internal staining of the teeth. The production and use of methamphetamines, which is a strong stimulant drug, is an increasing problem in the United States.
Speculation that oral consumption of the drug causes tooth decay by raising the acidity of users' mouths is also unsupported. Meth mouth is generally most severe in users who inject the drug, rather than those who smoke, ingest or inhale it.