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Total iron binding capacity (TIBC) is a blood test to see if you have too much or too little iron in the blood. Iron moves through the blood attached to a protein called transferrin. This test helps your doctor know how well that protein can carry iron in the blood.
Iron is bound to transferrin in the plasma. Total iron binding capacity. (TIBC) is a direct measure of level of transferrin.Transferrin levels are. reduced in inflammation. Level of transferrin saturation is particularly helpful if assessment of. early stages of iron overload with levels > 55% for males and > 50%.