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Q: Why is there a need to focus on breakthrough seizures? A: When an epilepsy patient experiences a sustained period of freedom from seizures (seizure control), then suddenly experiences a seizure, such an event is commonly referred to as a breakthrough seizure. When these breakthrough seizures occur, there can be severe clinical consequences for the patient.
1 A seizure is defined as a sudden, electrical discharge in the brain causing alterations in behavior, sensation or consciousness. 2  Seizures that appear to begin everywhere in the brain at once are classified as generalized seizures, while those beginning in one location of the brain are classified as partial seizures.