The signs and symptoms of acute inflammation: Redness; Swelling; Heat; Pain; Loss of function; All the above signs may be observed in specific instances, but no single sign must, as a matter of course, be present. These are the original, or cardinal signs of inflammation. Functio laesa is an apocryphal notion, as it is not unique to inflammation and is a characteristic of many disease states. *Full article available from Wikipedia
This information is just provided to give you piece of mind, as it is best to avoid the topical-use of retinol-containing products during pregnancy. It is the oral-administration of retinol that has been proven to cause severe birth defects. Please let us know what the company and your doctor says!
Entresto can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. If you have diabetes, do not use Entresto together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo, Valturna). Before taking this medicine