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MDRO definition. For epidemiologic purposes, MDROs are defined as microorganisms, predominantly bacteria, that are resistant to one or more classes of antimicrobial agents (1).imilarly, therapeutic options are limited for ESBL-producing isolates of gram-negative bacilli, strains of A. baumannii resistant to all antimicrobial agents except imipenem(8-11, 38) and intrinsically resistant Stenotrophomonas sp.(12-14, 39).
Multidrug-resistant organisms are bacteria that have become resistant to certain antibiotics, and these antibiotics can no longer be used to control or kill the bacteria. Antibiotics are important medicines. They help fight infections that are caused by bacteria. Bacteria that resist treatment with more than one antibiotic are called multidrug-resistant organisms (MDROs for short). Multidrug-resistant organisms are found mainly in hospitals and long-term care facilities. They often affect people who are older or very ill and can cause bad infections.