6. Stay on schedule. Try going to sleep at the same time every night, as well as waking up at the same time every morning. This trains your body to want to go to bed when it's time for you to go to bed, helping you get to sleep easier.
Prostaglandins provide a protective barrier that prevent the stomach from digesting itself. If there is a break in the protective barrier, mucosal injury occurs. Injury worsen by histamine release and vagal nerve stimulation. Hydrochloric acid diffuse back into the mucosa and injure small vessels. This causes edema, hemorrhage, and erosion of the stomach's lining.
So while it blocks prostaglandins that cause pain or cause clotting and narrowing of the blood vessels and inflammation, it also blocks prostaglandins that protect the stomach lining. Thatâs where stomach bleeding comes from when you take aspirin or other drugs in the aspirin family. Theyâre known as nonsteroidal anti-inflammatory drugs, or NSAIDs. Drugs in this family include ibuprofen (Motrin, Advil), naproxen (Aleve) and ketoprofen (Orudis). Aspirin causes the most irritation.