1 Pour over Tuna Steaks and marinade 20 minutes, turning occasionally. 2  Make sure grill is hot â place steaks in hottest section and Sear steaks 1 to 2 minutes per side to seal in the juices. 3  Finish cooking just slightly away from the hottest area â 8 to 10 minutes per inch of thickness.
The FcRI complex forms a high-affinity cell-surface receptor for the Fc region of antigen-specific immunoglobulin E (IgE) molecules. FcRI is multimeric and is a member of a family of related antigen/Fc receptors which have conserved structural features and similar roles in initiating intracellular signalling cascades.
In T-Cell Independent B-Cell Activation free floating antigen binds directly to the antibodies (B-Cell Receptor) on the surface of the B-cell. This type of B-Cell activation is less potent and does not result in isotype switching. This means that only IgM is created against the antigen.