Biochem/physiol Actions. DAPT is a Î³-secretase inhibitor and indirectly an inhibitor of Notch, a Î³-secretase substrate. Other Î³-secretase substrates include LDL receptor-related protein, E-cadherin and ErbB-4. As an inhibitor of Î³-secretase, DAPT may be useful in the study of Î²-amyloid (AÎ²) formation.
Types of Garbage Trucks There are generally five basic truck models: 1. Front loader. The truck is equipped with two automated lifting forks on the front of the vehicle. The driver positions the forks to align with the waste bin (or dumpster in the US), then the container is lifted and emptied in the back of the truck.
Front loaders, graders, dump trucks and other vehicles have been made with articulated joints to greatly reduce their turning radius. The most common models of articulated haulers are Caterpillar, Volvo, and Terex trucks ranging in tonnage from 25 to 40 ton.