1 Pour over Tuna Steaks and marinade 20 minutes, turning occasionally. 2  Make sure grill is hot â place steaks in hottest section and Sear steaks 1 to 2 minutes per side to seal in the juices. 3  Finish cooking just slightly away from the hottest area â 8 to 10 minutes per inch of thickness.
The FcRI complex forms a high-affinity cell-surface receptor for the Fc region of antigen-specific immunoglobulin E (IgE) molecules. FcRI is multimeric and is a member of a family of related antigen/Fc receptors which have conserved structural features and similar roles in initiating intracellular signalling cascades.
The antigen-binding site is the area of the antibody that recognizes the specific antigenic determinant and binds to the antigen. Since different antibodies recognize different antigens, antigen-binding sites are different for different antibodies. This area of the molecule is known as the variable region. IgD molecules are located on the surface membranes of mature B cells. 2  The heavy chain type in IgD is a delta chain. 3  IgE: Found mostly in saliva and mucus, these antibodies are involved in allergic responses to antigens. 4  The heavy chain type in IgE is an epsilon chain.