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Statistical Parametric Mapping. SPM (Statistical Parametric Mapping) refers to the construction and assessment of spatially extended statistical processes used to test hypotheses about functional imaging data. These ideas have been instantiated in software that is called SPM.
The software represents the implementation of the theoretical concepts of Statistical Parametric Mapping in a complete analysis package, as a suite of MATLAB (The MathWorks, Inc) functions and subroutines with some externally compiled C routines. 1  SPM website at the Wellcome Trust Centre for Neuroimaging, UCL, UK.