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Over-the-counter oral antihistamines, such as diphenhydramine (Benadryl), cetirizine (Zyrtec), fexofenadine (Allegra) and loratadine (Claritin), typically don't work nearly as well for nonallergic rhinitis as they do for allergic rhinitis.
Allergic Rhinitis: these patients should have significant nasal symptoms: This of course is treated with antihistamines, decongestants, nasal steroids, avoiding the offending material or taking allergy shots. 1  If the patient does not have significant sinonasal symptoms this is probably not the cause.