Biochem/physiol Actions. DAPT is a Î³-secretase inhibitor and indirectly an inhibitor of Notch, a Î³-secretase substrate. Other Î³-secretase substrates include LDL receptor-related protein, E-cadherin and ErbB-4. As an inhibitor of Î³-secretase, DAPT may be useful in the study of Î²-amyloid (AÎ²) formation.
Four Types of Trash Trucks. Side Loader Refuse Trucks. These types of trucks can be loaded either manually or automatically from the side. An Automated Side Loader or ASL is a garbage truck that has a mechanical arm with an automated lift that reaches out to the side of the truck and grabs a residential garbage container.
Typical commercial US dump trucks are double-axle dually setups carrying about 10 cubic yards of material, which is about 10 short tons for typical materials like gravel or soil. A big, heavy-duty triple-axle model might reach 15 tons. A single-axle model based on a passenger truck might only hold 3 tons. A side-dump semi trailer might hold 30 tons.