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Function. Because the lumen of the gastrointestinal tract is exposed to the external environment, much of it is populated with potentially pathogenic microorganisms. Peyer's patches thus establish their importance in the immune surveillance of the intestinal lumen and in facilitating the generation of the immune response within the mucosa.
The ileum also provides a place for the absorption of vitamin B12 and bile salts. One interesting modification that we see as we move into the ileum is the presence of local collections of lymphatic tissues called Peyer's patches.