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keratin filaments. Definitions: 1. a class of intermediate filaments that form a network within epithelial cells and anchor to desmosomes, thus imparting tensile strength to the tissue. Synonyms: cytokeratin filaments. The definition information for keratin filaments is provided by Stedman's.
Keratin is a fibrous structural protein of hair, nails, horn, hoofs, wool, feathers, and of the epithelial cells in the outermost layers of the skin. Keratin serves important structural and protective functions, particularly in the epithelium.