Negative Numbers to Zero. A clever Excel trick to change negative numbers to zero but leave positive numbers unchanged. Below you can find two columns with numbers. To subtract the numbers in column B from the numbers in column A, execute the following steps. 1. Select cell C1. 2. Enter the formula =A1-B1. 3. Click the lower right corner of cell C1 and drag the formula down. Result: 4. To change the negative numbers to zero but leave the positive numbers unchanged, instead of =A1-B1, use =MAX(0,A1-B1) and drag the function down. Result: Explanation: the MAX function returns the maximum of two values. If the result of the formula is negative, the function returns 0.
Dystrophin is a rod-shaped cytoplasmic protein, and a vital part of a protein complex that connects the cytoskeleton of a muscle fiber to the surrounding extracellular matrix through the cell membrane. This complex is variously known as the costamere or the dystrophin-associated protein complex.he dystrophin gene is one of the longest human genes known, covering 2.5 megabases (0.08% of the human genome) at locus Xp21.
DMD is caused by a mutation in the dystrophin gene -- usually a large, out-of-frame deletion. Dystrophin is a structural protein associated with the support scaffolding of plasma membrane in muscle cells. Absent dystrophin causes a weakening of muscles, particularly skeletal and cardiac muscle.