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They are most numerous in the palms and soles of feet. Sweat glands are more numerous & more widely distributed then Sudoriferous Glands. They open to the surface of the skin through sweat pores and secrete perspiration in response to nerve stimulation & heat.
Fortunately, most of the time having constantly sweaty hands is not a sign of a serious medical problem or illness. Rather, it just means that you have over active sweat glands, which is largely determined by your genetics. Over active sweat glands most often can occur in the feet, the palms of the hands, or the armpits. The medical term for over active sweat glands is hyperhidrosis.