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keratin filaments. Definitions: 1. a class of intermediate filaments that form a network within epithelial cells and anchor to desmosomes, thus imparting tensile strength to the tissue. Synonyms: cytokeratin filaments. The definition information for keratin filaments is provided by Stedman's.
The SC consists of layers of cornified keratinocytes (corneocytes) attached to each other by corneodesmosomes, with intercellular spaces sealed with lipids. The intracellular space of corneocytes is filled with keratin filaments, filaggrin, and their degradation products.