1 The first bomb dropped on Hiroshima was made from uranium. 2  The bomb dropped on Nagasaki was made from plutonium, which was even more powerful than uranium. 3  It is thought that at least 135,000 people died from the Hiroshima explosion and another 70,000 in Nagasaki.
Pharmacokinetic parameters of paclitaxel following 3- and 24-hour infusions of TAXOL at dose levels of 135 and 175 mg/m2 were determined in a Phase 3 randomized study in ovarian cancer patients and are summarized in the following table.
It is not known whether olaratumab passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine. How is olaratumab given? Olaratumab is injected into a vein through an IV. A healthcare provider will give you this injection. Olaratumab is given in a 21-day treatment cycle. You may receive the medicine only during the first 2 weeks of each cycle, on Day 1 and Day 8 of the full cycle. The day before you receive olaratumab, you may be given other IV medications to prevent certain side effects. Olaratumab must be given slowly, and the IV infusion can take at least 60 minutes to complete. For the first 8 treatment cycles, you will also be treated with doxorubicin.