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Function. Because the lumen of the gastrointestinal tract is exposed to the external environment, much of it is populated with potentially pathogenic microorganisms. Peyer's patches thus establish their importance in the immune surveillance of the intestinal lumen and in facilitating the generation of the immune response within the mucosa.
Peyerâs patches are round or oval and are located in the mucous membrane lining of the intestine. They can be seen by the naked eye as elongated thickened areas, and their surface is free of the projections (villi) and depressions (LieberkÃ¼hn glands) that characterize the intestinal wall.