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Dictionary entry overview: What does hopelessness mean? â¢ HOPELESSNESS (noun) The noun HOPELESSNESS has 1 sense: 1. the despair you feel when you have abandoned hope of comfort or success Familiarity information: HOPELESSNESS used as a noun is very rare.
Chronic pain in the adipose tissues, fatigue, weakness, joint and muscle aches, rapid heartbeat, sleep disturbances, diabetes. A mood disorder that causes a persistent feeling of sadness, hopelessness and and worthlessness; triggers vary but may include biological/genetic factors, hormones, life events etc.