Malignancy is one of the most common causes and must be excluded. Hyperparathyroidism and other causes of hypercalcemia can coexist with malignancy. If calcium levels have been mildly elevated for months or years, malignancy is an unlikely cause. Hypercalcemia from malignancy usually is rapidly progressive; thus, rapidly rising calcium levels should increase suspicion of malignancy.
Kailua-Kona on Hawaiiâs Big Island is the site of Kona Brewing Companyâs brewery and first restaurant. The brewpub opened in November 1998. Prominently featured ohia wood found throughout the pub came from South Kona.
For most people, traveling to the Grand Aleutian Hotel, located in Dutch Harbor on Unalaska Island midway down the Aleutian Island chain, is a bit out of the way even with the appeal of great seafood.