The signs and symptoms of acute inflammation: Redness; Swelling; Heat; Pain; Loss of function; All the above signs may be observed in specific instances, but no single sign must, as a matter of course, be present. These are the original, or cardinal signs of inflammation. Functio laesa is an apocryphal notion, as it is not unique to inflammation and is a characteristic of many disease states. *Full article available from Wikipedia
This information is just provided to give you piece of mind, as it is best to avoid the topical-use of retinol-containing products during pregnancy. It is the oral-administration of retinol that has been proven to cause severe birth defects. Please let us know what the company and your doctor says!
Ranitidine has been assigned to pregnancy category B by the FDA. Animal studies have failed to reveal evidence of fetal harm. There are no controlled data in human pregnancy. Ranitidine is known to cross the placenta, although it has been used safely during labor and delivery for the prevention of Mendelson's syndrome. Ranitidine is only recommended for use during pregnancy when benefit outweighs risk. In one study, ranitidine 50 mg was administered by slow intravenous injection to 20 women at 38 weeks gestation or more for the prevention of Mendelson's syndrome.