Biochem/physiol Actions. DAPT is a Î³-secretase inhibitor and indirectly an inhibitor of Notch, a Î³-secretase substrate. Other Î³-secretase substrates include LDL receptor-related protein, E-cadherin and ErbB-4. As an inhibitor of Î³-secretase, DAPT may be useful in the study of Î²-amyloid (AÎ²) formation.
Four Types of Trash Trucks. Side Loader Refuse Trucks. These types of trucks can be loaded either manually or automatically from the side. An Automated Side Loader or ASL is a garbage truck that has a mechanical arm with an automated lift that reaches out to the side of the truck and grabs a residential garbage container.
An internal packer blade periodically compresses the trash and moves it to the rear of the body. Front loaders are generally used to pick up trash at commercial businesses, and the containers are commonly called dumpsters, although that is a proprietary name for one manufacturer's design. Front loaders have capacities of about 30-40 cu yds (23.0-30.6 cu m) and can be operated with a crew of one.