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Q: Why is there a need to focus on breakthrough seizures? A: When an epilepsy patient experiences a sustained period of freedom from seizures (seizure control), then suddenly experiences a seizure, such an event is commonly referred to as a breakthrough seizure. When these breakthrough seizures occur, there can be severe clinical consequences for the patient.
Pediatric Epilepsy: Medical Intractability. Medical management with AEDs remains the treatment of choice for epilepsy in adults and children. Medically intractable epilepsy has been defined as persistent seizure activity, which, despite maximal medical treatment, remains sufficiently debilitating to warrant the risks of surgery. This definition has different meanings in the pediatric and adult epilepsy populations.