Before determining if a data point is an outlier, the normal data point value range must be determined. To do so, a random sample of a population must be taken, and the data points must be ordered from smallest to largest.
The currently recommended dose of naloxone is 0.1 mg/kg for infants and children from birth to 5 years of age or 20 kg of body weight. Children olden than 5 years of age or weighing more than 20 kg may be given 2.0 mg.
Naltrexone (Trexan) is also useful as a long term antagonistic. Laboratory detection of morphine and codeine is performed by immunoassay. Confirmation is by gas chromatography/mass spectrometry (GC/MS). The detection limit of the initial screen is 300 ng/ml, with a sensitivity of 20 ng/ml.