1 10. 2  Mechanism of Polymer Degradation and Erosion: ï The difference between polymer âdegradationâ and âerosionâ is not clear in many cases. 3  Biodegradable polymers undergo hydrolytic bond cleavage to form water soluble degradation products that can dissolve in an aqueous environment, resulting in polymer erosion. Mechanism of Hydrolytic Degradation ï Hydrolytic degradation of members of the polylactide/glycolide family proceeds through four stages as represented in Figure 2: First stage of water diffusion followed by second stage, in which oligomers with acidic endgroups autocatalyze the hydrolysis reaction.
Each 5 mg SALAGENÂ® Tablet for oral administration contains 5 mg of pilocarpine hydrochloride. Inactive ingredients in the tablet, the tablet's film coating, and polishing are: carnauba wax, hypromellose, microcrystalline cellulose, stearic acid, titanium dioxide and other ingredients. Each 7.5 mg SALAGENÂ® Tablet for oral administration contains 7.5 mg of pilocarpine hydrochloride. Inactive ingredients in the tablet, the tablet's film coating, and polishing are: carnauba wax, hypromellose, microcrystalline cellulose, stearic acid, titanium dioxide, FD&C blue#2 aluminum lake, and other ingredients.
Renagel is the tablet form of sevelamer hydrochloride launched by Genzyme Corporation in 1998. Renagel has been approved by the FDA for the reduction of serum phosphorus in hemodialysis patients with end-stage renal disease. Renagel is administered in tablet form. Eligibility Renagel Medicare Part D Assistance Program, a patient assistance program provided by Genzyme Corporation, offers Renagel at no cost for up to 1 year to those who are eligible for the program.