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MDRO definition. For epidemiologic purposes, MDROs are defined as microorganisms, predominantly bacteria, that are resistant to one or more classes of antimicrobial agents (1).imilarly, therapeutic options are limited for ESBL-producing isolates of gram-negative bacilli, strains of A. baumannii resistant to all antimicrobial agents except imipenem(8-11, 38) and intrinsically resistant Stenotrophomonas sp.(12-14, 39).
Infection means that bacteria are in or on your body and causing an illness or other medical condition. Infection with a MDRO occurs most often in young children, the elderly, or in people who have an existing severe illness or a health condition such as chronic lung, heart, or kidney disease.ultidrug-resistant organism infections are hard to treat because they do not respond to many common antibiotics, even the most powerful ones. But certain antibiotics can still help control MDROs in most people. The doctor will try to find the type of MDRO causing the illness.