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Key points. 1  Intestinal epithelial cells (IECs) provide a physical and biochemical barrier that segregates host tissue and commensal bacteria to maintain intestinal homeostasis. 2  Secretory IECs support this function through the secretion of mucins and antimicrobial peptides.ey points. 1  Intestinal epithelial cells (IECs) provide a physical and biochemical barrier that segregates host tissue and commensal bacteria to maintain intestinal homeostasis. 2  Secretory IECs support this function through the secretion of mucins and antimicrobial peptides.
The epithelium is a layer of cells-epithelial cells. They are highly specialised for selective secretion and absorption of ions and molecules. Epithelial cells line any surface that comes into contact with the external environment. So-the airways, the gut, the urinary tract, the cornea etc.Together with an underlying layer of connective tissue, they form mucous membranes. Epithelium may also line the surface of internal organs. An epithelial cells is said to be polarised as either side of the cell differs in terms of structure and function.o-the airways, the gut, the urinary tract, the cornea etc. Together with an underlying layer of connective tissue, they form mucous membranes. Epithelium may also line the surface of internal organs. An epithelial cells is said to be polarised as either side of the cell differs in terms of structure and function.