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You can alternate Tylenol and Ibuprofen as a pain medicine or anti inflammatory because Ibuprofen is metabolized by the kidneys and Acetamenophen is metabolized by the liver.So neither of the organs is overtaxed by overuse. You can take 2800mg of Tylenol daily and 3200mg of Advil daily, so do not exceed those doses.Do not take Advil and Aleve because both of those meds are metabolized by the kidneys. Advil contains Ibuprofen and Aleve contains Naproxen sodium.Both considered NSAID's (non-steroidal anti inflammatory drugs) as well as Acetamenophen (tylenol) .ou can take 2800mg of Tylenol daily and 3200mg of Advil daily, so do not exceed those doses. Do not take Advil and Aleve because both of those meds are metabolized by the kidneys. Advil contains Ibuprofen and Aleve contains Naproxen sodium.
Two of the most common over the counter NSAIDs are Ibuprofen (Advil, Brufen, or Motrin) and Naproxen (Aleve). Letâs take a look at the pros and cons of the two: Ibuprofen vs. Naproxen To begin, both ibuprofen and naproxen are NSAIDs, and they will both offer some relief to whatever is causing you pain. One difference is mainly within the speed in which they act. Ibuprofen is a fast acting drug, and will bring you relief much quicker than naproxen will.