The signs and symptoms of acute inflammation: Redness; Swelling; Heat; Pain; Loss of function; All the above signs may be observed in specific instances, but no single sign must, as a matter of course, be present. These are the original, or cardinal signs of inflammation. Functio laesa is an apocryphal notion, as it is not unique to inflammation and is a characteristic of many disease states. *Full article available from Wikipedia
This information is just provided to give you piece of mind, as it is best to avoid the topical-use of retinol-containing products during pregnancy. It is the oral-administration of retinol that has been proven to cause severe birth defects. Please let us know what the company and your doctor says!
If you take Depakote for seizures or manic episodes: Do not start or stop taking the medicine during pregnancy without your doctor's advice. Divalproex sodium may cause harm to an unborn baby, but having a seizure during pregnancy could harm both the mother and the baby.