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You can alternate Tylenol and Ibuprofen as a pain medicine or anti inflammatory because Ibuprofen is metabolized by the kidneys and Acetamenophen is metabolized by the liver.So neither of the organs is overtaxed by overuse. You can take 2800mg of Tylenol daily and 3200mg of Advil daily, so do not exceed those doses.Do not take Advil and Aleve because both of those meds are metabolized by the kidneys. Advil contains Ibuprofen and Aleve contains Naproxen sodium.Both considered NSAID's (non-steroidal anti inflammatory drugs) as well as Acetamenophen (tylenol) .ou can take 2800mg of Tylenol daily and 3200mg of Advil daily, so do not exceed those doses. Do not take Advil and Aleve because both of those meds are metabolized by the kidneys. Advil contains Ibuprofen and Aleve contains Naproxen sodium.
I'm wondering if I can take ibuprofen while on omeprazole, I get killer headaches a lot. Update: Oh, i'm not even prescribed for ibuprofen, only the omeprazole.I wonder if that matters.est Answer: I have acid reflux and get killer headaches, too, and yes, you can take them both at the same time. I have been doing so for a while now, they are both prescribed by my doctor. Source(s): The Queen Â· 7 years ago.