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keratin filaments. Definitions: 1. a class of intermediate filaments that form a network within epithelial cells and anchor to desmosomes, thus imparting tensile strength to the tissue. Synonyms: cytokeratin filaments. The definition information for keratin filaments is provided by Stedman's.
Alpha-keratins, which are found in the hair, the skin, and the wool of mammals, are primarily fibrous and helical in structure. By contrast, beta-keratins, which occur in birds and reptiles, consist of parallel sheets of polypeptide chains.