From this knowledge management definition we can see that it depends upon the management of the organization's knowledge creation and conversion mechanisms; organizational memory and retrieval facilities; organizational learning; and organizational culture.
A leaky mitral valve, or mitral regurgitation, can develop when the valve flaps (called leaflets) do not close effectively. This can happen either because the valve flaps are scarred or defective, or because the heart has become enlarged, stretching the valve opening so much that the flaps no longer meet in the center.
The most common causes for a leaky pulmonary valve is pulmonary hypertension or a congenital heart defect (most specifically, a defect called tetralogy of Fallot). Less common causes are: 1  Infective endocarditis. 2  Complications after surgery to repair tetralogy of Fallot. 3  Carcinoid syndrome.