A herniated disc in the lower back may be felt in the buttock and down the back of the leg to the ankle or foot. There may be low back pain, but usually not as severe as leg pain. Other symptoms of a herniated disc may include severe deep muscle pain and muscle spasms.
TsimTsum â In Kabbalah, the Tzimtzum (TsimTsum) meaning contraction, is the act by which the Creator removed His Limitlessness from the world so that Creation could occur. In the kabbalistic tradition, the Creator is referred to as Ein Sof (or Eyn Sof), meaning âwithout endâ. The Creator exists beyond all space, time, and limitation.
Tunicamycin (TM) is a chemical ER stress inducer that disrupts protein glycosylation and represents a high level of stress compared to metabolic stresses encountered during obesity. Treatment of mice with TM was shown to decrease expression of a number of genes involved in lipid metabolism.unicamycin (TM) is a chemical ER stress inducer that disrupts protein glycosylation and represents a high level of stress compared to metabolic stresses encountered during obesity. Treatment of mice with TM was shown to decrease expression of a number of genes involved in lipid metabolism.