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Key points. 1  Intestinal epithelial cells (IECs) provide a physical and biochemical barrier that segregates host tissue and commensal bacteria to maintain intestinal homeostasis. 2  Secretory IECs support this function through the secretion of mucins and antimicrobial peptides.ey points. 1  Intestinal epithelial cells (IECs) provide a physical and biochemical barrier that segregates host tissue and commensal bacteria to maintain intestinal homeostasis. 2  Secretory IECs support this function through the secretion of mucins and antimicrobial peptides.
The epithelial tissue functions in secretion, excretion, absorption and protection. The stratified squamous epithelium, also known as epidermis, makes up the outer layer of skin, and it serves an important protective function. As these cells age, they create a layer of keratinized epithelium.eratinized epithelium may cause hardening of the cells of the stomach lining. The tissue that lines the esophagus is a type of non-keratinized epithelium. View slideshow of images above. Watch the Did-You-Know slideshow.