2. bow down-bend one's knee or body, or lower one's head; He bowed before the King; She bowed her head in shame. bow. conge, congee-perform a ceremonious bow. gesticulate, gesture, motion-show, express or direct through movement; He gestured his desire to leave.
Sections. Definition. Gene regulation refers to the mechanisms that act to induce or repress the expression of a gene. These include structural and chemical changes to the genetic material, binding of proteins to specific DNA elements to regulate transcription, or mechanisms that modulate translation of mRNA. News and Comment.
Gene expression is governed by complex mechanisms including transcription factor binding to DNA and coordinated changes in chromatin structure. The primary protein components of chromatin are the histones, which are assembled along with DNA into larger complexes known as nucleosomes.odifications of histone proteins constitute an important mechanism of gene regulation. Histone modifications are an early indicator of epigenetic regulation, and one way to study this phenomenon is via chromatin immunoprecipitation (ChIP).