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The Fractionator Principle. The fractionator principle is one of the important concepts used in stereology. The importance of this principle cannot be overlooked. It appears in many different places. Although it looks different depending on how it is used, the principle is the same.
Fractionation. A laboratory test or process in which blood or another fluid is broken down into its components. Fractionation can be used to assess the proportions of the different types of cholesterol in a blood sample.ractionation. 1. in radiology, division of the total dose of radiation into small doses administered at intervals. 2. in chemistry, separation of a substance into components, as by distillation or crystallization. 3. in histology, isolation of components of living cells by differential centrifugation.