The signs and symptoms of acute inflammation: Redness; Swelling; Heat; Pain; Loss of function; All the above signs may be observed in specific instances, but no single sign must, as a matter of course, be present. These are the original, or cardinal signs of inflammation. Functio laesa is an apocryphal notion, as it is not unique to inflammation and is a characteristic of many disease states. *Full article available from Wikipedia
This information is just provided to give you piece of mind, as it is best to avoid the topical-use of retinol-containing products during pregnancy. It is the oral-administration of retinol that has been proven to cause severe birth defects. Please let us know what the company and your doctor says!
It should not be used during pregnancy. It is best to use 5-fluorouracil during the winter months, generally for two to eight weeks. Sometimes 5-fluorouracil is prescribed with tretinoin cream. This combination works best if the tretinoin has been used for at least two weeks prior to starting 5-fluorouracil. Tretinoin cream enhances the effect of 5-fluorouracil by peeling off the top layer of skin.