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Certain heart diseases. Heart diseases, including aortic valve disease, left heart failure, mitral valve disease, and congenital heart disease, can also cause pulmonary hypertension. Thromboembolic disease. A blood clot in a large pulmonary artery can result in the development of pulmonary hypertension.
Pulmonary embolism occurs when there is a deep vein thrombosis in which there is a blood clot. The blood clot travels up into the lungs. Symptoms include shortness of breath, chest pain, and cough. Treatment for pulmonary embolism includes surgery and medication. A common drug class used to treat pulmonary embolism is the anticoagulants drug class.