Figure 3: Vasodilation produced by the direct effects of caffeine on the VSMC. Caffeine inhibits the voltage-dependent Ca2+ channels and the entrance of calcium to the cytoplasm. In addition, it inhibits the IP3 receptor and increases the ânon-contractile Ca2+.
Instructions. 1. Fill the bottom of the pan with a layer of water. 2. Add the vinegar. 3. Bring the pan to the boil. It should be looking a bit cleaner already. 4. Remove the pan from the heat and add the baking soda. Expect fizz! 5.Empty the pan and scour as normal; if necessary add an extra bit of dry baking soda.6. If there are any super stubborn marks that don't come off with scouring, make a paste of baking soda and a couple of drops of water.. Remove the pan from the heat and add the baking soda. Expect fizz! 5. Empty the pan and scour as normal; if necessary add an extra bit of dry baking soda. 6. If there are any super stubborn marks that don't come off with scouring, make a paste of baking soda and a couple of drops of water.
Instructions. 1  Bring water to a boil: Pour the water into the pot, then bring it to a boil over medium heat. 2  Add baking soda: When the water begins to boil, add the baking soda, stir with a wooden spoon, and let simmer for a few minutes.3  Scrape: Use the wooden spoon to scrape the burned-on bits off of the pot. Rinse: Pour the baking soda and water solution down the drain, rinse the pot with hot water, then wipe it dry. 2  If you have a very large pot to clean (or the burned on bits go far up the sides of the pot), just use more of the cleaning solution. 3  For every quart of water, use two tablespoons of soda.