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AstraZeneca produced revolutionary oncology drugs and expanded its diabetes treatments with the purchase of its partner Bristol-Myers Squibbsâ entire diabetes division in 2014. The buyout brought drugs like Byetta (exenatide injection) and Bydureon to AstraZeneca.
SGLT2 Inhibitors, Farxiga, Invokana, Jardiance. Dangerous New Drugs The FDA recently gave its approval to several new drugs that are part of a new class of diabetes drugs, the SGLT2 inhibitors. All have very troubling side effects. More are awaiting approval. The first of these was Johnson & Johnson's drug canagliflozin, which is marketed in the U.S. as Invokana. It is also sold in a combination pill containing metformin as Invokamet. These sodium-glucose co-transporter-2 (SGLT-2) inhibitors lower blood sugar by blocking reabsorption of glucose by the kidney and increasing its excretion in urine.