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Iron deficiency anemia  causing blue skin under the eyes. If there is a shortage of iron in the body, oxygen cannot be properly transported by the blood. Hemoglobin is the oxygen transporting component in the blood, moving oxygen from the lungs to the cells where it is released for normal cell metabolism.
Symptoms of iron-deficiency anemia are related to decreased oxygen delivery to the entire body and may include: 1  Being pale or having yellow sallow skin. 2  Unexplained fatigue or lack of energy. 3  Shortness of breath or chest pain, especially with activity. 4  Unexplained generalized weakness. 5  Rapid heartbeat.