Buprenorphine has become both medication and dope: a treatment with considerable successes and also failures, as well as a street and prison drug bedeviling local authorities. It has attracted unscrupulous doctors and caused more health complications and deaths than its advocates acknowledge.
Psychosociological theory. In addition to theories of aging based on molecules and cells, there also exists a âpsychosociologicalâ theory of aging. As people grow older, their behaviour changes, their social interactions change, and the activities in which they engage change.
Comment in Aging Cell. 2003 Feb;2(1):9-10. The mitochondrial theory of aging is based around the idea of a vicious cycle, in which somatic mutation of mtDNA engenders respiratory chain dysfunction, enhancing the production of DNA-damaging oxygen radicals.In turn, this is proposed to result in the accumulation of further mtDNA mutations.omment in Aging Cell. 2003 Feb;2(1):9-10. The mitochondrial theory of aging is based around the idea of a vicious cycle, in which somatic mutation of mtDNA engenders respiratory chain dysfunction, enhancing the production of DNA-damaging oxygen radicals.