What are the side effects of alteplase (TPA, Activase, Cathflo Activase)? The most common and serious side effect of alteplase is bleeding. Minor bleeding is more common, but significant bleeding such as into the brain (intracranial hemorrhage) or fatal bleeding also occurs. Other important side effects include:
Overview. 1  Surgical treatment for vaginal prolapse involves supporting the vaginal defect that is causing the pelvic organ to prolapse into the vagina. For example, a cystocele is a weakness in the front wall of the vagina, near the bladder. A cystocele repair involves sewing the submucosal vaginal tissue back together where it has stretched.
Prolapse of the uterus is usually fixed with surgery, but you can also use a vaginal pessary to help keep the uterus in place. A pessary can help if you have a cystocele (when your bladder droops down into your vagina) or if you have a rectocele (when the wall of your rectum bulges into the bottom of your vagina).he pessary is most often used for prolapse of the uterus. Prolapse means that your uterus droops or sags into the vaginal canal because the muscles and ligaments that should support it are weak.