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In Dupuytren's (say duh-pwee-TRAHNZ) disease, tissue under the skin in the palm of your hand, called the palmar fascia, gets thicker and shorter. This can cause your fingers to bend in toward your palm. It most often affects the ring and small fingers, usually of both hands.
The swelling makes it difficult for the affected tendon to slide through its membrane (tendon sheath), causing the pain and stiffness associated with trigger finger. The swelling can cause a section of the tendon to become bunched into a small lump (nodule) at the base of the affected finger or thumb. If a nodule forms, the tendon can get trapped in the tendon sheath, causing the affected finger or thumb to become temporarily stuck in a bent position.