Vitamin D has a number of important functions, and one of which is regulating the amount of calcium we have in the body. When you donât have enough vitamin D, you can end up with bone deformities. The combination of vitamin D and calcium is therefore essential to keep your bones and muscles healthy, and when you donât have enough of it, youâll experience bone pain and conditions like osteomalacia.
Ibrutinib is freely soluble in dimethyl sulfoxide, soluble in methanol and practically insoluble in water. IMBRUVICA (ibrutinib) capsules for oral administration are supplied as white opaque capsules that contain 140 mg ibrutinib as the active ingredient.
Total revenue for the quarter ended December 31, 2014 increased to $290 million from $124 million in the same period in the prior year, primarily due to a $172 million increase in IMBRUVICA net product revenue year over year.