Much research has also been conducted on everolimus and other mTOR inhibitors as targeted therapy for use in a number of cancers. It is marketed by Novartis under the tradenames Zortress (USA) and Certican (Europe and other countries) in transplantation medicine, and Afinitor in oncology. Everolimus also available with Biocon with the brand name of Evertor.
Female fox and gray squirrels that are at least two years old have two litters per year, younger females have only one litter per year. Average litter size is two to four (southern flying squirrels may have litters of up to seven young), with young weaned around eight weeks of age.
Cottontails can raise as many as 6 litters in a year. Typically, there are 2 to 3 litters per year in northern parts of the cottontail range and up to 5 to 6 in southern areas. In the north (Wisconsin), first litters are born as early as late March or April. In the south (Texas), litters may be born year-round. Litter size also varies with latitude; rabbits produce 5 to 6 young per litter in the north, 2 to 3 in the south. The rabbit's gestation period is only 28 or 29 days, and a female is usually bred again within a few hours of giving birth. Rabbits give birth in a shallow nest depression in the ground.