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The usual dose of naproxen is 250 mg, 375 mg, or 500 mgâtwice a day in the morning and evening for conditions like rheumatoid arthritis, osteoarthritis, or ankylosing spondylitis. Enteric-coated naproxen is usually taken in doses of 375 or 500 mg twice a day.
I like Naproxen (OTC) for antiinflammatory relief. I think it works better than Ibuprofen and is only twice a day. The OTC dose is 220 mg twice a day. It comes in prescription strength of 500mg twice a day.