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Neuropathic arthropathy (or neuropathic osteoarthropathy), also known as Charcot joint (often Charcot foot), refers to progressive degeneration of a weight bearing joint, a process marked by bony destruction, bone resorption, and eventual deformity.Onset is usually insidious.europathic arthropathy (or neuropathic osteoarthropathy), also known as Charcot joint (often Charcot foot), refers to progressive degeneration of a weight bearing joint, a process marked by bony destruction, bone resorption, and eventual deformity.
Inflammation plays a key role in the pathophysiology of the Charcot foot and is the earliest clinical finding. The occurrence of acute foot/ankle fractures or dislocations in neuropathic individuals is considered active CN because of the inflammatory process of bone healing, even in the absence of deformity.