For example the median expected annual pay for a typical Psychologist in the United States is $88,776, so 50% of the people who perform the job of Psychologist in the United States are expected to make less than $88,776.Source: HR Reported data as of October 2015. 1  Salary. 2  Salary + Bonus.3  Benefits. 4  Purchase Full Report.or example the median expected annual pay for a typical Psychologist in the United States is $88,776, so 50% of the people who perform the job of Psychologist in the United States are expected to make less than $88,776. Source: HR Reported data as of October 2015.
Pyrazinamide was first discovered and patented in 1936 but not used against tuberculosis until 1952. [19] Its discovery as an anti-tubercular agent was remarkable since it has no activity against tuberculosis in-vitro, due to not being active at a neutral pH, so would ordinarily not be expected to work in-vivo. [27]
Although evidence based on an experiment done with 5-chloropyrazinamide, a close analog of pyrazinamide, on M. smegmatis suggested that fatty acid biosynthesis I (FAS-I) is the potential target of pyrazinoic acid, 62 this hypothesis was later questioned. 63 Recently, a new mechanism of action for pyrazinamide was proposed, suggesting that disruption of the proton motive force and energy production is the basis of its antibacterial activity. 64 According to this hypothesis, pyrazinoic anion ...