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During the first appointment at the clinic you receive the mifepristone pill to take orally. Then 24 to 72 hours later, in the privacy of your own home, you take the the second medication, misoprostol. Misoprostol causes contractions resulting in a miscarriage.
Misoprostol, when given in full doses (800 mcg/day) is very effective in preventing ulcers, and ulcer complications in patients taking NSAIDs. Unfortunately, its usefulness is limited by its GI side effects. When given in lower doses its side-effect profile is the same as that of PPIs, and it is equally effective.