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There was also a second physician named Bernard Sachs who recognized the familial nature of the disorder and also observed numerous cases. He witnessed that Tay Sachs disease was most common in the European, Jewish origin. Â· When was Tay Sachs disease discovered?Tay Sachs disease was discovered in the year of 1880.
Tay-Sachs disease and resistance to tuberculosis. Tay-Sachs is a rare genetic disease that results in an abnormal accumulation of neuronal lipids caused by a defective lysosomal enzyme, Î±-hexosaminidase. Alleles for this disease are more prevalent in certain populations, the most well-known being the Ashkenazi Jews.t is of note that a particular genetic disorder leads to infectious disease hypersusceptibility, and this relationship has provided the basis for a preventative. Specifically, the relationship between hemosiderosis and typhoid fever has led to the development of a vaccine that intervenes in this relationship.