The rate and extend in which the amount of drug substance dissolved over a period of time is called dissolution. It is expressed as percentage release of drug substances present dosage forms such Tablets, Capsules, oral suspensions and ointments. In our present study dissolution method development for various kinds of tablets such as immediate release or instant release, modified, Extended release and Enteric coated.
pKa Definition: pK a is the negative base-10 logarithm of the acid dissociation constant of a solution.
Boric acid is a weak acid, with pKa (the pH at which buffering is strongest because the free acid and borate ion are in equal concentrations) of 9.24 in pure water at 25 Â°C. But apparent pKa is substantially lower in swimming pool or ocean waters because of interactions with various other molecules in solution.