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Antidepressants and anti-psychotic medications can disrupt your cycle and cause you to skip periods or get them more frequently. âMany of these medications elevate a pituitary hormone called prolactin, which can alter other hormones in your body that regulate your cycle,â Minkin says.
Periods also lighten when girls start to ovulate more regularly, and make more progesterone. Here are some simple ways to reduce heavy menstrual flow in teenagers: 1  A conventional anti-inflammatory like ibuprofen (Advil or Nurofen) blocks prostaglandins and reduces menstrual flow by half.