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The drugâs initial approval noted mild side effects such as vomiting, itching, lethargy and diarrhea. Some 70 million doses of Trifexis have been distributed through 15,000 veterinary clinics, said Elanco spokeswoman Julie Lawless.
Heartworm infection can make dogs very sick and can even be fatal. This parasite is spread to dogs by mosquitoes. Trifexis can prevent flea infestations from becoming established, and can also remove any fleas that are on your dog at the time of treatment.