Federal direct subsidized loans are based on financial need. The federal government pays the interest during in-school, grace and deferment periods. Federal direct unsubsidized loans are not based on financial need, and the federal government does not pay the interest for these loans. Students may choose to defer interest payments until repayment begins; however, the student is responsible for all interest that accrues.
1 Outdoor air pollution can cause ongoing throat irritation. Indoor pollution â tobacco smoke or chemicals â also can cause a chronic sore throat. Chewing tobacco, drinking alcohol and eating spicy foods also can irritate your throat.  Muscle strain.
1 Users also may be at risk for cancer of the voice box, esophagus, colon and bladder, because they swallow some of the toxins in the juice created by using smokeless tobacco. 2  Smokeless tobacco can irritate your gums, causing gum (periodontal) disease.