What are the side effects of alteplase (TPA, Activase, Cathflo Activase)? The most common and serious side effect of alteplase is bleeding. Minor bleeding is more common, but significant bleeding such as into the brain (intracranial hemorrhage) or fatal bleeding also occurs. Other important side effects include:
Overview. 1  Surgical treatment for vaginal prolapse involves supporting the vaginal defect that is causing the pelvic organ to prolapse into the vagina. For example, a cystocele is a weakness in the front wall of the vagina, near the bladder. A cystocele repair involves sewing the submucosal vaginal tissue back together where it has stretched.
Women with moderate to severe symptoms may opt for surgery or a pessary, a vaginal support device thatâs inserted into the vagina. Surgical options differ based on the nature of the prolapse, a womanâs goals for treatment and any coexisting bladder or bowel dysfunction requiring treatment.