What are the side effects of alteplase (TPA, Activase, Cathflo Activase)? The most common and serious side effect of alteplase is bleeding. Minor bleeding is more common, but significant bleeding such as into the brain (intracranial hemorrhage) or fatal bleeding also occurs. Other important side effects include:
Overview. 1  Surgical treatment for vaginal prolapse involves supporting the vaginal defect that is causing the pelvic organ to prolapse into the vagina. For example, a cystocele is a weakness in the front wall of the vagina, near the bladder. A cystocele repair involves sewing the submucosal vaginal tissue back together where it has stretched.
Options include: 1  Hysterectomy âThis is the removal of the uterus through the vagina. This will permanently resolve uterine prolapse, but it also results in infertility. 2  Vaginal repairâThis is usually done with a hysterectomy. The repair can be done with sutures and with sutures alone or with insertion of mesh and slings.