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The dose (volume of injection in mL) per month = patient weight (kg) x 15 mg per kg Ã· 100 mg per mL of Synagis. Injection volumes over 1 mL should be. given as a divided dose. â¢ Synagis is supplied as a single-dose vial and does not contain preservatives.
In pediatric patients less than 24 months of age, the mean half-life of SynagisÂ®. (palivizumab) was 20 days and monthly intramuscular doses of 15 mg/kg achieved mean Â±SD 30. day trough serum drug concentrations of 37 Â±21 Âµg/mL after the first injection, 57 Â±41 Âµg/mL after.