The rate and extend in which the amount of drug substance dissolved over a period of time is called dissolution. It is expressed as percentage release of drug substances present dosage forms such Tablets, Capsules, oral suspensions and ointments. In our present study dissolution method development for various kinds of tablets such as immediate release or instant release, modified, Extended release and Enteric coated.
pKa Definition: pK a is the negative base-10 logarithm of the acid dissociation constant of a solution.
Updated February 09, 2017. Ka is the equilibrium constant for the dissociation reaction of a weak acid. A weak acid is one which only partially dissociates in water or an aqueous solution. The value of Ka is used to calculate pH of weak acids. The pKa value is used to choose a buffer when needed.