SR 20 is closed in both directions from the Loup Loup Pass summit at milepost 215 to Rock Creek at milepost 223 due to water over the roadway and mud slides. Currently there is no estimated time for reopening and no local detour available.
Warfarin and Digoxin Toxicity. Medication Toxicity Signs and Symptoms. Warfarin Â­. CoumadinÂ®. Bleeding â¢ headache, dizziness, or weakness. â¢ bleeding from shaving or other cuts that does not. stop. â¢ nosebleeds.
The effects of digoxin in heart failure are mediated by its. positive inotropic and neurohormonal deactivating effects, whereas the effects of the drug in. atrial arrhythmias are related to its vagomimetic actions. In high doses, digoxin increases. sympathetic outflow from the central nervous system (CNS).