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1 Metaplastic cells (immature squamous cells) New squamous cells at the squamocolumnar junction are continuously replacing columnar cells. 2  These new squamous cells are called metaplastic cells.3  The area of cell replacement is called the transformation zone. The normal cervix has two types of cells on the surfaceâsquamous cells and columnar (glandular or mucus producing) cells. 2  Additionally, new squamous cells are identified as metaplastic cells.
Medical Definition of Squamous cells. Squamous cells: Flat cells that look like fish scales. The word squamous came from the Latin squama meaning the scale of a fish or serpent.. We have a lot of squamous cells. They make up most of the cells in the outer layer of the skin (the epidermis), the passages of the respiratory and digestive tracts, and the linings of the hollow organs of the body.