The next âSilent Sundays at South Mountain Park is April 23. On this special access day the roadways are exclusively available to non-motorized traffic. Visitors are encouraged to hike, bicycle, take strollers, or otherwise enjoy the park without the noise and congestion of traffic on the park roads.
The term sickle cell disease (SCD) describes a group of inherited red blood cell disorders. People with SCD have abnormal hemoglobin, called hemoglobin S or sickle hemoglobin, in their red blood cells. Hemoglobin is a protein in red blood cells that carries oxygen throughout the body.âInheritedâ means that the disease is passed by genes from parents to their children.ormally, hemoglobin in red blood cells takes up oxygen in the lungs and carries it to all the tissues of the body. Red blood cells that contain normal hemoglobin are disc shaped (like a doughnut without a hole).
The globin genes encode the globin chains that make up hemoglobin (Hb). More than 1000 polymorphic variants of the globin genes have been characterized, consisting of single nucleotide substitutions through to complex gene rearrangements.