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A purified protein derivative (PPD) skin test is a test that determines if you suffer from tuberculosis (TB). Tuberculosis is a serious infection, usually of the lungs, caused by the bacteria Mycobacterium tuberculosis. This bacteria spreads by breathing in the air exhaled by an infected person.
The Mantoux skin test consists of an intradermal injection of one-tenth of a milliliter (ml) of PPD tuberculin. The size of induration is measured 48â72 hours later. Erythema (redness) should not be measured. The Mantoux test or Mendel-Mantoux test (also known as the Mantoux screening test, tuberculin sensitivity test, Pirquet test, or PPD test for purified protein derivative) is a screening tool for tuberculosis (TB).