Each of the five types of conotoxins attacks a different target: 1  Î±-conotoxin attacks acetylcholine receptors at nerves and muscles. 2  Î´-conotoxin inhibits the inactivation of voltage-dependent sodium channels. 3  Îº-conotoxin inhibits potassium channels. 4  Î¼-conotoxin inhibits voltage-dependent sodium channels in muscles. Ï-conotoxin inhibits N-type voltage-dependent calcium channels. Because N-type voltage-dependent calcium channels are related to algesia (sensitivity to pain) in the nervous system, Ï-conotoxin has an analgesic effect: the effect of Ï-conotoxin M VII A is 100 to 1000 times that of morphine.
Master Sgt. Peter Andrew McKenna, a Green Beret, was killed in a Taliban attack at a US Special Forces base in Kabul, Afghanistan on Friday. Rhode Island Sen. Jack Reed, who met McKenna at the parade and presented him with the flag, called him a 'truly great citizen, soldier, person and patriot' in a tweet on Sunday.
Jonathan Crombie, Anne of Green Gables actor, dead at 48. Jonathan Crombie played Gilbert Blythe in the CBC productions of 'Anne of Green Gables.' He was born on Oct. 12, 1966 in Toronto. Jonathan Crombie, who played Gilbert Blythe in the Anne of Green Gables movies, has died at the age of 48. He was also the son of David Crombie, who was mayor of Toronto from 1972 to 1978 and served as a federal Progressive Conservative cabinet minister in the 1980s.