TEM-1 is the most commonly encountered beta-lactamase in Gram-negative bacteria. Up to 90% of ampicillin resistance in E. coli is due to the production of TEM-1. Also responsible for the ampicillin and penicillin resistance that is seen in H. influenzae and N. gonorrhoeae in increasing numbers.
The Game Plan (film) The Game Plan is a 2007 American family comedy film directed by Andy Fickman and written by Nichole Millard, Kathryn Price and Audrey Wells and starring Dwayne The Rock Johnson (marking the last film in which Johnson uses his ring name The Rock in billing).
The film was directed and written by Peter Landesman, based on the 2009 GQ expose Game Brain by Jeanne Marie Laskas. The film also stars Alec Baldwin, Gugu Mbatha-Raw and Albert Brooks. Columbia Pictures will release the film December 25, 2015.