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1 Surrounding the mucosa is the submucosa layer of the stomach. 2  The submucosa is made up of various connective tissues, blood vessels, and nerves. 3  Connective tissues support the tissues of the mucosa and connect it to the muscularis layer.
The stomach has an internal lining, or mucous membrane, called the gastric mucosa. The mucosa must create hydrochloric acid to break down food, but also protect itself from the acidic contents that it creates. This delicate balance is controlled by three different glands in the lining of the stomach.