The cause of Tay-Sachs disease is a genetic defect (mutation) that is passed from parent to child. This genetic defect is located in the HEXA gene, which is found on chromosome 15.The HEXA gene makes part of an enzyme called beta-hexosaminidase A, which plays a critical role in the nervous system.he cause of Tay-Sachs disease is a genetic defect (mutation) that is passed from parent to child. This genetic defect is located in the HEXA gene, which is found on chromosome 15.
A more common cause of bladder pain is urinary tract infection (UTI), which can also produce changes in urine color, difficulty urinating, and a feeling of fullness in the bladder. Sometimes these infections are âsilentâ and donât have any symptoms until they worsen significantly.
Bladder infections are caused by bacteria in the bladder. Escherichia coli (E. coli) is usually the bacteria that causes a bladder infection. Bladders normally have a small amount of bacteria in them and urinating helps flush out the bacteria, but sometimes the bacteria grows so fast it causes a bladder infection. Effects Bladder infections can cause a frequent or urgent need to urinate. They can also cause pain, itchiness or a burning sensation during urination. Urine can smell and look different when the bladder is infected. Like other bacterial infections, a bladder infection can also cause fever, chills and fatigue.