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The dose (volume of injection in mL) per month = patient weight (kg) x 15 mg per kg Ã· 100 mg per mL of Synagis. Injection volumes over 1 mL should be. given as a divided dose. â¢ Synagis is supplied as a single-dose vial and does not contain preservatives.
Determine maintenance dose using the following. Each maintenance dose (approx. 15-20 mg/kg of actual body weight, rounded to the nearest 250 mg) should be. administered at the dosing interval recommended for a patien tâs CrCL. Maximum initial dose is 1750 mg every 12 hours until. serum concentration monitoring indicates the need for higher dosing.