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anion gap The Anion Gap is an approximate measurement of ions, that is molecules with a charge, either negative or positive. Sodium and potassium are positively charged and therefore called cations; this is why they are often represented as Na + and K + respectively.
As a consequence, the mean serum anion gap in many clinical laboratories that use ion selective electrodes is lower than reported previously, averaging 6 Â± 3 mEq/L (13,15). Indeed, in one study, two separate laboratories that used these methods reported that 62 and 79% of healthy individuals had a serum anion gap of 6 mEq/L or less .