Structure of intermediate filament. Intermediate filaments (IFs) are cytoskeletal components found in the cells of vertebrate animal species, and perhaps also in other animals, fungi, plants, and unicellular organisms. They are composed of a family of related proteins sharing common structural and sequence features.
The United States Constitution was ratified by New Hampshire on June 21, 1788, when New Hampshire became the ninth state to do so. New Hampshire was a Jacksonian stronghold; the state sent Franklin Pierce to the White House in the election of 1852.
In December 1787, Delaware became the first state to ratify the document. On June 21, 1788, New Hampshire ratified the constitution, giving it the theoretically sufficient endorsement of nine states, but New York and Virginia had yet to agree. Without them, the federal government couldn't function. Four days later, Virginia signed on and after another month, so did New York.