The rate and extend in which the amount of drug substance dissolved over a period of time is called dissolution. It is expressed as percentage release of drug substances present dosage forms such Tablets, Capsules, oral suspensions and ointments. In our present study dissolution method development for various kinds of tablets such as immediate release or instant release, modified, Extended release and Enteric coated.
pKa Definition: pK a is the negative base-10 logarithm of the acid dissociation constant of a solution.
Unlike cell cycle-dependent protein kinase 2 and mitogen-activated protein kinase, the catalytic (C) subunit of cAMP-dependent protein kinase (PKA) normally is assembled as an active enzyme with a fully phosphorylated activation loop (9, 10).