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Junior Member. It takes approximately 5.5 half lives before the drug is completely out of your system. As the half life is 2 hours it would take about 11 hours (2 hours x 5.5 half lives) before diclofenac would have been out of your system,so theoretically you would have been diclofenac free by 4.30 am. So it was safe for you to take Zoloft at 9.30 am.
Many antimicrobials have been used to treat C. difficile colitis. Oral vancomycin and metronidazole used for 7 to 10 days are considered the first line of therapy by most clinicians and current guidelines. Multiple studies have reported initial response rates greater than 90% and comparable failure rates of 15% to 20%.