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What causes heavy periods. Diagnosing what causes heavy periods can sometimes be difficult. However, some physical condition affecting the uterus, such as fibroids and polyps, may cause heavy menstrual bleeding. The more common reasons for heavy periods are: fibroids. polyps. endometrial hyperplasia. endometrial cancer. adenomyosis.
Common causes of ovulatory bleeding (heavy or prolonged menstrual bleeding) include: 1  Structural problems, such as uterine fibroids or polyps. 2  Bleeding disorders, such as leukemia, platelet disorders, the various factor deficiencies, or von Willebrand disease. 3  Hypothyroidism. Advanced liver disease.