Guy Fieris Vegas Kitchen - This restaurant specializes in American cuisine and serves brunch, lunch, and dinner. Guests can enjoy drinks at the bar. Chayo Mexican Kitchen - This restaurant specializes in Mexican cuisine and serves lunch and dinner. Guests can enjoy drinks at the bar.
Genetics. 1  Achondroplasia is a single gene disorder caused by mutations in the FGFR3 gene on chromosome 4. 2  Two different mutations in the FGFR3 gene cause more than 99 per cent of cases of achondroplasia. 3  It is a dominant genetic disease so only one copy of the FGFR3 gene needs to be mutated for symptoms to develop.chondroplasia is a genetic disorder affecting bone development that results in short-limb dwarfism. 1  Achondroplasia is the most common form of short-limb dwarfism, a disorder in which bone tissue does not develop properly, especially the long bones of the arms and legs.
Alternatively, some genes may be in regions of chromosomes which are more susceptible to genetic damage/change or may contain sequences which are more likely to be altered by spontaneous mutations; the achondroplasia gene is known to contain a hot spot of the latter type (a CpG sequence, discussed below). third type of spontaneous DNA damage that occurs frequently is damage to the bases by free radicals of oxygen. These arise in cells as a result of oxidative metabolism and also are formed by physical agents such as radiation.