The cause of Tay-Sachs disease is a genetic defect (mutation) that is passed from parent to child. This genetic defect is located in the HEXA gene, which is found on chromosome 15.The HEXA gene makes part of an enzyme called beta-hexosaminidase A, which plays a critical role in the nervous system.he cause of Tay-Sachs disease is a genetic defect (mutation) that is passed from parent to child. This genetic defect is located in the HEXA gene, which is found on chromosome 15.
A more common cause of bladder pain is urinary tract infection (UTI), which can also produce changes in urine color, difficulty urinating, and a feeling of fullness in the bladder. Sometimes these infections are âsilentâ and donât have any symptoms until they worsen significantly.
A UTI often causes the bladder and urethra to be sensitive resulting in pain with urination, frequency of urination, and the feeling of an urgent need to urinate (even though only a small amount of urine may be passed). There is sometimes blood in the urine. UTIs can also be symptom-free. Men may also have a discharge from the tip of the penis.