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Iron deficiency anemia  causing blue skin under the eyes. If there is a shortage of iron in the body, oxygen cannot be properly transported by the blood. Hemoglobin is the oxygen transporting component in the blood, moving oxygen from the lungs to the cells where it is released for normal cell metabolism.
Symptoms of Iron-Deficiency Anemia. Inadequate supply of oxygen to the cells due to iron deficiency causes symptoms such as pale skin, cold hands and feet, extreme fatigue, weakness, increased heart rate, breathlessness, dizziness, headaches, irritability, inflammation of the tongue and brittle nails. heme group at the end of each polypeptide chain contains an iron atom, which binds with oxygen and transports it throughout the body. Oxygenated hemoglobin molecules in red blood cells give blood its bright red color.