Now available at the Mac App Store for free, Mac OS X 10.10 Yosemite was first announced at the Worldwide Developers Conference in June, and is the second update to be named after a place in Apple's home state of California, after last year's Mavericks.
Gaucher disease is the most common of the lipid storage diseases. It is caused by a deficiency of the enzyme glucocerebrosidase. Fatty material can collect in the spleen, liver, kidneys, lungs, brain, and bone marrow.ipids are fat-like substances that are important parts of the membranes found within and between each cell and in the myelin sheath that coats and protects the nerves. Lipids include oils, fatty acids, waxes, steroids (such as cholesterol and estrogen), and other related compounds.
Jim Yeadon, Ph.D. Should I use Apoe- or Ldlr-deficient mice for atherosclerosis studies? Mice deficient in either Apolipoprotein E (Apoe) or Low density lipoprotein (Ldl) receptor (Ldlr) almost certainly are the two most commonly used mouse models for hyperlipidemia and atherosclerosis research. Both APOE and LDLR are important for the clearance of cholesterol and triglyceride-rich lipoprotein particles from the blood.