FDAâs Breakthrough Therapy Designation. The Breakthrough Therapy Designation (BTD) came into force in July 2012 after the Food and Drug Administration Safety and Innovation Act (FDASIA) was approved by Congress.
SoBe (stylized as SoBE) is an American brand of teas, fruit-juice blends and enhanced water beverages owned by PepsiCo. The name SoBe is an abbreviation of South Beach, named after the upscale area located in Miami Beach, Florida. In the past, the SoBe name has also been licensed for gum and chocolate products. SoBe switched from glass bottles to plastic bottles for all of its beverages in 2010.
El Sobrante. El Sobrante is a community of about 12,670 people located in the northeast section of District 1. The greater El Sobrante Valley includes portions that are within the City of Richmond. Primary government service providers: El Sobrante Municipal Advisory Council (ESMAC) A volunteer board of residents, appointed by Supervisor Gioia, that advises the Board of Supervisors on local issues. County Sheriff's Department.