i love The Backstreet Boys soooo much, especially Nick Carter. i also love Nick's little brother - AAron Carter, love his rock !!! So this book is helpful to me and BSB,Aaron's fan !!!!
Lipogenesis is the process by which acetyl-CoA is converted to fatty acids.The former is an intermediate stage in metabolism of simple sugars, such as glucose, a source of energy of living organisms. Through lipogenesis and subsequent triglyceride synthesis, the energy can be efficiently stored in the form of fats.nsulin stimulates lipogenesis primarily by activating two enzymatic pathways. Pyruvate dehydrogenase (PDH), converts pyruvate into acetyl-CoA. Acetyl-CoA carboxylase (ACC), converts acetyl-CoA produced by PDH into malonyl-CoA.
(Note the thick arrow in thediagram.)The most important regulator of phosphofructokinase is fructose-2,6-bisphosphate, which is produced by a separate enzyme. Fructose-2,6-bisphosphateincreases the affinity of phosphofructokinase for fructose-6-phosphate, and thusacts as a critically important stimulator.ATP inhibits phosphofructokinase,because high levels of ATP indicate that the cell has sufficient energy.Phosphofructokinase is also inhibited by citrate.hile glucose-6-phosphate can be used for a number of other pathways,and the phosphoglucoisomerase reaction is freely reversible, the compound fructose-1,6-bisphosphate is committed to glycolysis. Phosphofructokinase is the primarycontrol point for glycolysis, and is tightly regulated.