Best Answer: A contract can be oral or in writing. Some contracts must be in writing such as a contract for the sale of land. An IOU is legal even on the back of a bubblegum wrapper if it is signed by both parties and dated but it does not have to be in writing.eport Abuse. Yes, it is legally binding, providing that other statutes weren't broken in obtaining the IOU or in the agreement itself. If you threatened someone to get them to sign it, it's not legal. If it's for an illegal enterprise, it is not legal. If you are charging excessive interest, again, not legal.
For the purposes of clarity, in this review we define acquired keratoderma as a non-hereditary, non-frictional hyperkeratosis of the palms and/or soles that involves â¥50% of the surface of involved acral areas and that may or may not be associated with clinical and histologic inflammation.
Systemic sclerosis (systemic scleroderma) is a chronic connective tissue disease of unknown etiology that causes widespread microvascular damage and excessive deposition of collagen in the skin and internal organs. Raynaud phenomenon and scleroderma (hardening of the skin) are hallmarks of the disease.The typical patient is a young or middle-age woman with a history of Raynaud phenomenon who presents with skin induration and internal organ dysfunction.aynaud phenomenon and scleroderma (hardening of the skin) are hallmarks of the disease. The typical patient is a young or middle-age woman with a history of Raynaud phenomenon who presents with skin induration and internal organ dysfunction.