From Wikipedia, the free encyclopedia. An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells. conformational epitope is composed of discontinuous sections of the antigen's amino acid sequence. These epitopes interact with the paratope based on the 3-D surface features and shape or tertiary structure of the antigen. The proportion of epitopes that are conformational is unknown.
Dear fortysomething: Yes, we do get questions about itchy nipples or burning nipples. The least common causes, but the most serious, would be inflammatory breast cancer or Paget's Disease (another type of breast cancer).
Jogger's nipple is a common condition experienced by runners, caused when the nipples chafe against clothing during physical activity. The symptoms of jogger's nipple are irritation, soreness, redness of the skin and dryness. If the condition persists the nipples may crack and bleed. It can be treated by using some antiseptic cream to treat the irritation and prevent infection.