What is Quad Screening? Quad Screening is a prenatal test to determine the likelihood that a fetus (unborn baby) is affected with trisomy 21 (Down syndrome), trisomy 18, and certain types of birth defects (open neural tube defect or abdominal wall defects). Chromosome abnormalities (e.g. trisomy 21, trisomy 18) occur more frequently as a woman ages.
(From bottom left to bottom right) Michael Fishman as D.J. Conner, Sara Gilbert as Darlene Conner, Roseanne Barr as Roseanne Conner, John Goodman as Dan Conner and Sarah Chalke as Becky Conner. The following is a list of major characters in the television series Roseanne.
Roseanne (Roseanne Barr) is a line worker at Wellman Plastics, along with her sister Jackie (Laurie Metcalf) and friend Crystal (Natalie West). Jackie has a brief relationship with Booker (George Clooney), the foreman at Wellman.