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Effect of prednisone on thyroid gland morphology and plasma thyroxine and triiodothyronine concentrations in the dog. Woltz HH, Thompson FN, Kemppainen RJ, Munnell JF, Lorenz MD.
Prednisone is a drug that is commonly used to treat many inflammatory conditions. It is often prescribed to treat the two major forms of inflammatory bowel disease (IBD)âCrohn's disease and ulcerative colitis. The chief barrier to use of prednisone is its long list of potential side effects, many of which are visible or especially bothersome. Some of these prednisone effects include: insomnia, mood swings, increased hair growth, facial swelling or mooning, increased appetite, night sweats, acne, headaches, and weight gain. In more extreme cases, the long-term use of prednisone can lead to steroid dependency, bone density loss, and other permanent adverse effects.