Sphere of influence. In the field of international relations, a sphere of influence (SOI) is a spatial region or concept division over which a state or organization has a level of cultural, economic, military, or political exclusivity, accommodating to the interests of powers outside the borders of the state that controls it.
Multiple myeloma is named for the clock face appearance of these cancer cells when seen under a microscope. They infiltrate virtually all of a patient's bone marrow. In x-ray images of multiple myeloma, it looks like holes have been punched out of the bone.
Multiple myeloma is a malignant tumour of a type of white blood cell (the plasma cell). Blood cells of all types are made in the bone marrow, which in adults occupies the central position of bones â such as the vertebrae, ribs, pelvis and skull.