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As a general rule, antibiotics do not cause a decrease of white blood cells (WBCs). WBCs are one of the main ways the body fights infection. Because your son had a recent illness the WBC count most likely increased during that period in order to fight his infection.
Side effects of long-term antibiotic use linked to oxidative stress. Holly MacCormick on July 5, 2013. Mitochondria in healthy cells (left). Mitochondria in cells damaged by oxidative stress after treatment with the antibiotic ciprofloxacin (right). Antibiotics may stamp out bacterial infections, but when taken for long periods of time these drugs stamp like bulls in a china shop kicking up side effects varying in severity from headache to hearing loss.