Pulmonary surfactant, secreted via exocytosis of lamellar bodies (LB) by alveolar type II (AT II) cells, maintains low alveolar surface tension and is therefore essential for normal lung function.
This in turn causes abnormalities in the levels of the other hormones, Estrogen and Progesterone, thus adding to the chemical turmoil in the body. The common causes of Anovulatory Cycles include: Polycystic Ovarian Disease (PCOD). Hyperprolactinaemia (increased blood levels of the hormone Prolactin).
Pathophysiology. To understand anovulation, one must first understand what occurs during a normal ovulatory cycle. In normal physiology, ovulation is dependent on the presence of a functioning hypothalamic-pituitary-ovarian (HPO) axis.