From Wikipedia, the free encyclopedia. An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells. conformational epitope is composed of discontinuous sections of the antigen's amino acid sequence. These epitopes interact with the paratope based on the 3-D surface features and shape or tertiary structure of the antigen. The proportion of epitopes that are conformational is unknown.
Dear fortysomething: Yes, we do get questions about itchy nipples or burning nipples. The least common causes, but the most serious, would be inflammatory breast cancer or Paget's Disease (another type of breast cancer).
You will know right away if you have a nipple problem. You might see discharge, such as pus or a white, watery fluid. You may also feel pain, itchiness, or swelling in your nipples. See your doctor right away if you have any discharge at all or discomfort that lasts for more than a few days. You may also notice changes in the shape of your nipple(s) or in the areola (the skin around your nipple), such as puckering or dimpling of the skin. Always discuss changes like this with your doctor. Monthly discomfort that lasts just a few days could be related to hormone fluctuations during your menstrual cycle.