Compar-ison of extrapyramidal signs in dementia with Lewy bodies andParkinsonâs disease. J Neuropsychiatry Clin Neurosci 2001;13:374â379.45. Stern Y, Marder K, Tang MX, Mayeux R. Antecedent clinicalfeatures associated with dementia in Parkinsonâs disease. Neurol-ogy 1993;43:1690â1692.46.
Osteoarthritis is a joint disease that mostly affects cartilage. Cartilage is the slippery tissue that covers the ends of bones in a joint. Healthy cartilage allows bones to glide over each other. It also helps absorb shock of movement.
With aging, the water content of the cartilage increases, and the protein makeup of cartilage degenerates. Eventually, cartilage begins to degenerate by flaking or forming tiny crevasses. In advanced osteoarthritis, there is a total loss of the cartilage cushion between the bones of the joints.