Sphere of influence. In the field of international relations, a sphere of influence (SOI) is a spatial region or concept division over which a state or organization has a level of cultural, economic, military, or political exclusivity, accommodating to the interests of powers outside the borders of the state that controls it.
Multiple myeloma is named for the clock face appearance of these cancer cells when seen under a microscope. They infiltrate virtually all of a patient's bone marrow. In x-ray images of multiple myeloma, it looks like holes have been punched out of the bone.
1 Well-differentiated liposarcoma is the most common subtype and usually starts as a low grade tumor. Low grade tumor cells look much like normal fat cells under the microscope and tend to grow and change slowly.  Myxoid liposarcoma is an intermediate to high grade tumor.