Adrenal insufficiency. Adrenal insufficiency is a condition in which the adrenal glands do not produce adequate amounts of steroid hormones, primarily cortisol; but may also include impaired production of aldosterone (a mineralocorticoid), which regulates sodium conservation, potassium secretion, and water retention.
(Cocaine Toxicity or Overdose) An overdose may cause severe anxiety, panic, agitation, aggression, sleeplessness, hallucinations, paranoid delusions, impaired judgment, tremors, seizures, and delirium. Mydriasis and diaphoresis are apparent, and heart rate and BP are increased. Death may result from MI or arrhythmias.
Though alcohol, sedatives, or a mix of opioids (either prescription or illicit) are frequently involved in many opioid-related overdose deaths, opioid overdoses do sometimes occur after a person accidentally takes too much of their prescription medication.