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Suboxone is made of two drugs-buprenorphine and naloxone. The buprenorphine is what sticks around in your system and prevents withdrawl. It has a 36 hour half-life. So if yo â¦ u took 2mg of suboxone one time only, 36 hours later you'd have 1mg left in your system. 36 hours after that you'd have .5 mg in your system.
to find your necessary dose of suboxone, u really have to let yourself start to be in withdrawl, this means being off of fentanyl about 36 hours. the doctor generally will have you come in early so he can assess you- see how bad the withdrawal is and start you on an inital dose.