Any disease that causes extensive damage to the pancreas may lead to diabetes (for example, chronic pancreatitis and cystic fibrosis). Diseases associated with excessive secretion of insulin-antagonistic hormones can cause diabetes (which is typically resolved once the hormone excess is removed). This form was previously referred to as insulin-dependent diabetes mellitus (IDDM) or juvenile diabetes. 2  The cause is unknown. 3  Type 2 DM begins with insulin resistance, a condition in which cells fail to respond to insulin properly. 4  As the disease progresses a lack of insulin may also develop.
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A total of 1068 adults hospitalized with cUTI including pyelonephritis received Zerbaxa 1.5 g (1 g/0.5 g IV) every 8 hours or levofloxacin (750 mg IV) once daily for 7 days. Zerbaxa 375 mg IV every 8 hours for patients with CrCl 15 to 29 ml/min. 2  End-stage renal disease (ESRD) patients on hemodialysis: A loading dose of Zerbaxa 750 mg IV with a maintenance dose of 150 mg, every 8 hours.