Doyle is first seen in a conference room with Dr. John Brand. He is also the first person in the mission who docks Ranger 1 & 2 to the Endurance. Later, he, Cooper, Amelia, and CASE go down to the water planet Miller.
Structure and function of the yeast URA3 gene: expression in Escherichia coli. Rose M, Grisafi P, Botstein D. The expression of the cloned Saccharomyces cerevisiae URA3 gene in Escherichia coli on both plasmid and phage vectors was studied.Isolates of the gene from two different laboratory strains of yeast differ in their ability to be expressed in E. coli in the absence of external adjacent promoters of transcription.The DNA sequence of the two genes was determined and revealed several differences in the DNA flanking the structural gene.One base change alters the Pribnow-box of an E. coli promoter present in the yeast sequences.solates of the gene from two different laboratory strains of yeast differ in their ability to be expressed in E. coli in the absence of external adjacent promoters of transcription. The DNA sequence of the two genes was determined and revealed several differences in the DNA flanking the structural gene.
CYP3A4 is a member of the cytochrome P450 family of oxidizing enzymes. Several other members of this family are also involved in drug metabolism, but CYP3A4 is the most common and the most versatile one. Like all members of this family, it is a hemoprotein, i.e. a protein containing a heme group with an iron atom. In humans, the CYP3A4 protein is encoded by the CYP3A4 gene. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1.