Sphere of influence. In the field of international relations, a sphere of influence (SOI) is a spatial region or concept division over which a state or organization has a level of cultural, economic, military, or political exclusivity, accommodating to the interests of powers outside the borders of the state that controls it.
Multiple myeloma is named for the clock face appearance of these cancer cells when seen under a microscope. They infiltrate virtually all of a patient's bone marrow. In x-ray images of multiple myeloma, it looks like holes have been punched out of the bone.
Myeloma and multiple myeloma refer to the same disease. There are different types of myeloma, and classifications are made by the activity of the disease, as well as by the types of antibodies, or immunoglobulin proteins, that are being abnormally produced. A person who is first diagnosed with myeloma may or may not have any symptoms.