HHNKC is also known as diabetic hyperglycemic hyperosmolar coma (HHOC), hyperosmolar nonketotic coma (HONK), hyperosmolar hyperglycemic state (HHS) or hyperosmolar hyperglycemic nonketotic syndrome (HHNS). In HHNKC, blood sugar levels rise, and your body tries to get rid of the excess sugar by passing it into your urine.
Pressures sores result from the death (necrosis) of tissues due to local deprivation of blood supply, and thus of oxygen (ischemic necrosis). This is why tissue compression is the first clinical sign of pressure sores; it blocks the small blood vessels supplying tissues.
Coagulative necrosis is the most common type of necrosis in which cells death happen after exogenous or endogenous stimuli, occurring after such stresses as ischemia, virus toxin, physical and chemical injury. It is manifested by severe cell rupture, denaturation and coagulation of cytoplasmic proteins.