From Wikipedia, the free encyclopedia. An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells. conformational epitope is composed of discontinuous sections of the antigen's amino acid sequence. These epitopes interact with the paratope based on the 3-D surface features and shape or tertiary structure of the antigen. The proportion of epitopes that are conformational is unknown.
Dear fortysomething: Yes, we do get questions about itchy nipples or burning nipples. The least common causes, but the most serious, would be inflammatory breast cancer or Paget's Disease (another type of breast cancer).
new nipple inversion is usually evaluated with a breast examination and mammogram as a first step breast skin changes skin problems can develop on or near the breast some of which cause itching scaling or crusting dimpling swelling redness or changes in skin coloroncyclical breast pain is usually caused by a problem outside the breast such as muscle or connective tissue strain skin injury spinal conditions or problems in another organ system eg heart burn chest pain noncyclical breast pain is caused by breast cancer in only a very small percentage of women