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What areas did the Lewis and Clark expedition and the Pike expedition explore? Lewis and Clark explored the Northern part of the Louisiana Purchase, traveling up the Missouri River, and Pike explored the southern half, looking for the start of the Red River. Why were Meriwether Lewis and William Clark chosen to lead the exploration of the Louisiana Purchase? Lewis was chosen because of his experience as a leader, and Clark was chosen for his mapmaking skills.
A Shoshone woman who joined the Lewis and Clark expedition as a guide and interpreter Meriwether Lewis (1774-1809) Army captain appointed by President Jefferson to explore the Louisiana Territory and lands west to the Pacific Ocean William Clark (1770-1838) American soldier and friend of Meriwether Lewis, he was invited to explore the Louisiana Purchase and joined what became known as the Lewis and Clark expedition. Aaron Burr 3rd Vice President of the United States who served under President Thomas Jefferson; tied Jefferson for electoral votes in the election of 1800