Sarcoidosis leads to organ damage in about one-third of the people diagnosed with the disease. Damage may occur over many years and involve more than one organ. Rarely, sarcoidosis can be fatal. Death usually is the result of problems with the lungs, heart, or brain.Poor outcomes are more likely in people who have advanced disease and show little improvement from treatment.owever, it's more likely to affect some organs than others. The disease usually starts in the lungs, skin, and/or lymph nodes (especially the lymph nodes in your chest). Also, the disease often affects the eyes and liver.
The church of Santa Croce in Florence is most known for the famous Italians buried there (which is why it is referred to as the church of 'Italian Glories'). This basilica is the final resting place of many renowned Italians such as Michelangelo, Machiavelli and composer Gioacchino Rossini just to name a few.
Florence's cathedral stands tall over the city with its magnificent Renaissance dome designed by Filippo Brunelleschi, with the baptistery right across. The cathedral named in honor of Santa Maria del Fiore is a vast Gothic structure built on the site of the 7th century church of Santa Reparata, the remains of which can be seen in the crypt. The cathedral was begun at the end of the 13th century by Arnolfo di Cambio, and the dome, which dominates the exterior, was added in the 15th century on a design of Filippo Brunelleschi. A statue to each of these important architects can be found outside to the right of the cathedral, both admiring their work for the rest of eternity.