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Cri-du-chat syndrome: Rare Disease Status. Cri-du-chat syndrome is listed as a rare disease by the Office of Rare Diseases (ORD)...more Â» Cri-du-chat syndrome: Rare Disease Status. Cri-du-chat syndrome is listed as a rare disease by Ophanet, a consortium of European partners ...more Â» About statistics: This page presents a variety of statistics about Cri-du-chat syndrome.
Background. CREST (calcinosis, Raynaud phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia) syndrome is a member of the heterogeneous group of sclerodermas, and its name is an acronym for the cardinal clinical features of the syndrome.n 1910, Thibierge and Weissenbach described the first case report of what was later called CRST (calcinosis cutis, Raynaud phenomenon, sclerodactyly, and telangiectasia) syndrome in English by Winterbauer who, in 1964, described a series of 8 patients with the features that make up the abbreviation CRST.