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On 12 April 1961, Russian cosmonaut Yuri Gagarin became the first human to travel into space when he launched into orbit on the Vostok 3KA-3 spacecraft (Vostok 1).
Space Shuttle Columbia (Orbiter Vehicle Designation: OV-102) was the first space-rated orbiter in NASA's Space Shuttle fleet. It launched for the first time on mission STS-1 on April 12, 1981, the first flight of the Space Shuttle program.