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Effect of prednisone on thyroid gland morphology and plasma thyroxine and triiodothyronine concentrations in the dog. Woltz HH, Thompson FN, Kemppainen RJ, Munnell JF, Lorenz MD.
Common side effects of both prednisone and dexamethasone include retention of sodium (salt) and fluid, weight gain, high blood pressure (hypertension), potassium loss, headache, muscle weakness, nausea, vomiting, acne, thinning skin, restlessness, and psychiatric disturbances (depression, euphoria, insomnia, mood swings, personality changes, and psychotic behavior).