Sphere of influence. In the field of international relations, a sphere of influence (SOI) is a spatial region or concept division over which a state or organization has a level of cultural, economic, military, or political exclusivity, accommodating to the interests of powers outside the borders of the state that controls it.
Multiple myeloma is named for the clock face appearance of these cancer cells when seen under a microscope. They infiltrate virtually all of a patient's bone marrow. In x-ray images of multiple myeloma, it looks like holes have been punched out of the bone.
Multiple myeloma symptoms. Multiple myeloma is a relatively rare cancer that develops in the bone marrow. As the cancerous plasma cells accumulate in the marrow, other healthy blood cells are crowded out. This can cause several different symptoms, such as infection, anemia and problems with bruising and bleeding.