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Definition of node 1 a: a pathological swelling or enlargement (as of a rheumatic joint) b: a discrete mass of one kind of tissue enclosed in tissue of a different kind
Virchowâs Node. Virchowâs node (or signal node) is a lymph node in the left supraclavicular fossa (the area above the left clavicle). It takes its supply from lymph vessels in the abdominal cavity. Virchowâs node is also sometimes coined âthe seat of the devilâ given its ominous association with malignant disease. The finding of an enlarged, hard node (also referred to as Troisierâs sign) has long been regarded as strongly indicative of the presence of cancer in the abdomen, specifically gastric cancer, that has spread through the lymph vessels.