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Summary Information: Valve Cusps Valve Cusps: Valve cusps are located in the valves of the heart and are flaps of tissue that open in one direction as blood is pumped through them. The valve cusps are made of thin fibrous tissue, covered with a smooth membrane (endocardium) and reinforced by connective tissue.
Healthy valves open and close in coordination with the pumping action of your heart's atria and ventricles. Each valve has a set of flaps called leaflets or cusps that seal or open the valve. The cusps allow pumped blood to pass through the chambers and into your blood vessels without backing up or flowing backward.