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Answer by DRS (621) Typically, a bulls eye rash is caused by the bite of a Lyme disease carrying deer tick. This rash has a red spot in the center, with a larger red area circling it. A circular rash, however, could also be ringworm. Ringworm is a fungal infection of the skin.
Bullous pemphigoid occurs when the immune system attacks the skin and causes blistering. People develop large, itchy blisters with areas of inflamed skin. Doctors can diagnose bullous pemphigoid by examining skin samples under a microscope and checking for certain antibody deposits.