i love The Backstreet Boys soooo much, especially Nick Carter. i also love Nick's little brother - AAron Carter, love his rock !!! So this book is helpful to me and BSB,Aaron's fan !!!!
Lipogenesis is the process by which acetyl-CoA is converted to fatty acids.The former is an intermediate stage in metabolism of simple sugars, such as glucose, a source of energy of living organisms. Through lipogenesis and subsequent triglyceride synthesis, the energy can be efficiently stored in the form of fats.nsulin stimulates lipogenesis primarily by activating two enzymatic pathways. Pyruvate dehydrogenase (PDH), converts pyruvate into acetyl-CoA. Acetyl-CoA carboxylase (ACC), converts acetyl-CoA produced by PDH into malonyl-CoA.
Regulation of Acetyl-CoA Carboxylase: Acetyl-CoA Carboxylase, which converts acetyl-CoA to malonyl-CoA, is the committed step of the fatty acid synthesis pathway. The mammalian enzyme is regulated by phosphorylation, and there is allosteric control via local metabolites.Conformational changes associated with regulation:egulation of Acetyl-CoA Carboxylase by local metabolites: 1  Palmitoyl-CoA, the product of Fatty Acid Synthase, promotes the inactive conformation of Acetyl-CoA Carboxylase (diagram above), diminishing production of malonyl-CoA, the precursor of fatty acid synthesis. 2  This is an example of feedback inhibition.