In other words: A Permutation is an ordered Combination. There are basically two types of permutation: 1  Repetition is Allowed: such as the lock above. It could be 333.  No Repetition: for example the first three people in a running race. You can't be first and second.
For this reason, the idea that collagen supplementation can be an effective treatment for joint pain, osteoarthritis, or any other condition, is highly implausible, if not impossible in principle.
Glucosamine is a supplement derived from shellfish. Glucosamine is primarily sold as a joint health supplement. Studies show that supplementing glucosamine sulfate will reduce the rate of collagen (joint tissue) degradation and symptoms of osteoarthritis.