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Humira costs approximately $3,100 per month, like the TNFÎ± inhibitor etanercept. From 2012 to US patent expiry in 2016, Humira led the list of top-selling pharmaceutical products, and in 2016, it had $16 billion of global sales. Also in 2014, in India, the first adalimumab biosimilar came to market at a price of $200.
As noted in an investment analysis: The annual WAC price of Otezla is $22,500 which is at a discount to the price of injectable biologics for PsA. By comparison, the annual WAC cost of Enbrel and Humira is around $30-$35k while the annual WAC cost of Stelara is $40k-$70k. Celgene has noted that the effective price of Otezla will be less than the WAC as they plan to offer rebates which will likely vary across payors.