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1 Taussig Bing syndrome: A very rare birth defect where the aorta and the pulmonary artery both exit from the right ventricle and thus blood is unable to be pumped to the lungs.
Tauopathies are a class of neurodegenerative diseases associated with the pathological aggregation of tau protein in the human brain. The best-known of these illnesses is Alzheimer's disease (AD), wherein tau protein is deposited within neurons in the form of neurofibrillary tangles (NFTs).They were first described by the eponymous Alois Alzheimer in one of his patients suffering from the disorder.These aggregations of hyperphosphorylated tau protein are also referred to as PHF, or  paired helical filaments ). The precise mechanism of tangle formation is not completely understood, and it is still controversial as to whether tangles are a primary causative factor in the disease or play a more peripheral role.