I enjoy teaching. I enjoy teaching my patients about their disease process and informing them of the options they have. I explain to patients about their options, and the procedures in as much detail as a patient wants to hear. I hope to treat every patient as I want to be treated.
What is the drug for? ENTRESTO is a drug to be taken in conjunction with other heart failure therapies for the long-term treatment of chronic heart failure. This is a condition in which the heart is weak and cannot pump enough blood to meet the bodyâs needs.
Mechanism of Action. Entresto is a combination of sacubitril, a neprilysin inhibitor, and valsartan, an angiotensin II receptor blocker. Entresto inhibits neprilysin (neutral endopeptidase; NEP) via LBQ657, the active metabolite of the prodrug sacubitril, and blocks the angiotensin II type-1 (AT1) receptor via valsartan.