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Cause (including risk factors) Charcot foot occurs in patients with peripheral neuropathy resulting from diverse conditions including diabetes mellitus, leprosy, syphilis, poliomyelitis, chronic alcoholism or syringomyelia. Repetitive microtrauma that exceeds the rate of healing may cause fractures and dislocations.
All these are located in the forefoot and midfoot. Charcot foot is a very serious condition that can lead to foot deformities, disability, or even amputation. Charcot foot usually affects only one foot, but 20 percent of patients develop it in both feet.