In other words: A Permutation is an ordered Combination. There are basically two types of permutation: 1  Repetition is Allowed: such as the lock above. It could be 333.  No Repetition: for example the first three people in a running race. You can't be first and second.
For this reason, the idea that collagen supplementation can be an effective treatment for joint pain, osteoarthritis, or any other condition, is highly implausible, if not impossible in principle.
Good nutrition and a balanced, low-fat diet rich in fresh vegetables and fruit are a must! Look for foods that are high in vitamin C like broccoli, bell peppers, citrus fruits, cabbage, cauliflower, spinach, and strawberries, to reduce the risk of osteoarthritis. Foods like fortified dairy products and fish such as salmon, halibut, sea bass, tuna, cod, and herring are rich in Vitamin D which helps preserve cartilage. Calcium, found in milk and other dairy products as well as in broccoli, salmon and kale, will help strengthen bones.