A backfire is when the ignition of fuel doesn't take place in the ignition/combustion chamber, it(a backfire) can take place in the intake or exhaust. It can â¦ be caused by a fuel to air ratio not being correct, also if the timing of the spark is not just right that could cause it to back fire.
Melanoma in the United States. From 2005 to 2009, the median age at diagnosis for melanoma of the skin was 61, and the median age at death was 68. The age-adjusted incidence rate was 21.0 per 100,000 men and women per year.
This melanoma usually appears as a flat or barely raised , often with irregular borders and variations in color. These melanoma lesions most commonly appear on the trunks of men, the legs of women, and the upper back of both sexes. These lesions are diagnosed most frequently in patients between the ages of 30 and 50.