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THURSDAYS 8|7c. The Death of Derek Shepherd. Derek Shepherd (Patrick Dempsey) dies after a tragic car accident on Grey's Anatomy. Watch this scene from Season 11, Episode 21: How to Save a Life to see the heartbreaking moment Meredith Grey (Ellen Pompeo) says her final goodbye to her husband.
'Grey's Anatomy': Shonda Rhimes on Why She Had to Kill Off McDreamy. Fans were stunned last season when âGreyâs Anatomyâ killed off Dr. Derek Shepherd aka McDreamy, but show creator Shonda Rhimes says it could not have gone down any other way. Eonline.com posted an exclusive bonus clip from the Season 11 DVD, featuring Shondaâs explanation for why Derek (played by Patrick Dempsey) had to die.