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But, this was not the case for US dancer, Whitney Thore, who gained around 90 kilograms in just a year thanks to a disorder that affects womenâs hormones and ovaries. Polycystic ovary syndrome (PCOS) is an endocrine disorder that creates a hormonal imbalance in woman.
Characteristics of the Disease. Limb-girdle muscular dystrophy type 2B (LGMD2B) is a degenerative myopathy characterized by weakness and atrophy. Individuals with LGMD generally show weakness and wasting restricted to the limb musculature, proximal greater than distal.Proximal weakness refers to weakness of the muscles closer to the center of the body, including the shoulder, pelvic girdle, upper thighs, and upper arms.ndividuals with LGMD generally show weakness and wasting restricted to the limb musculature, proximal greater than distal. Proximal weakness refers to weakness of the muscles closer to the center of the body, including the shoulder, pelvic girdle, upper thighs, and upper arms.