In other words: A Permutation is an ordered Combination. There are basically two types of permutation: 1  Repetition is Allowed: such as the lock above. It could be 333.  No Repetition: for example the first three people in a running race. You can't be first and second.
For this reason, the idea that collagen supplementation can be an effective treatment for joint pain, osteoarthritis, or any other condition, is highly implausible, if not impossible in principle.
A trial on the effects of the oral combination product AR7 , which includes sternum collagen II, methylsulfonylmethane, cetyl myristoleate, lipase, vitamin C, and bromelain, was published. 9 In 89 patients with osteoarthritis, a decrease in the percentage of patients reported to have pain, stiffness, and tenderness in the treatment group was found after 3 months.