Sphere of influence. In the field of international relations, a sphere of influence (SOI) is a spatial region or concept division over which a state or organization has a level of cultural, economic, military, or political exclusivity, accommodating to the interests of powers outside the borders of the state that controls it.
Multiple myeloma is named for the clock face appearance of these cancer cells when seen under a microscope. They infiltrate virtually all of a patient's bone marrow. In x-ray images of multiple myeloma, it looks like holes have been punched out of the bone.
To do this they look at whether your myeloma is affecting your body tissue and organs and causing symptoms. The symptoms they check for are called CRAB which stands for. 1  Calcium (high levels). 2  Renal (kidney damage). 3  Anaemia (low levels of red blood cells).4  Bone damage.o do this they look at whether your myeloma is affecting your body tissue and organs and causing symptoms. The symptoms they check for are called CRAB which stands for. 1  Calcium (high levels). 2  Renal (kidney damage). 3  Anaemia (low levels of red blood cells). 4  Bone damage.