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As a general rule, antibiotics do not cause a decrease of white blood cells (WBCs). WBCs are one of the main ways the body fights infection. Because your son had a recent illness the WBC count most likely increased during that period in order to fight his infection.
Side effects of long-term antibiotic use linked to oxidative stress. Mitochondria in healthy cells (left). Mitochondria in cells damaged by oxidative stress after treatment with the antibiotic ciprofloxacin (right).