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Spirillum. a genus of gram-negative, spiral, and curved bacteria, including one species, S. miÂ´nus, that is pathogenic for guinea pigs, rats, mice, and monkeys and is the cause of rat-bite fever in humans.piÂ·rilÂ·la. A member of the genus Spirillum. /SpiÂ·rilÂ·lum/ (spi-rilÂ´um) a genus of gram-negative bacteria. The species S. miÂ´nus is pathogenic for guinea pigs, rats, mice, and monkeys and is the cause of rat-bite fever (sodoku) in humans.
Although most bacteria are harmless or often beneficial, several are pathogenic. One of the bacterial diseases with the highest disease burden is tuberculosis, caused by the bacterium Mycobacterium tuberculosis, which kills about 2 million people a year, mostly in sub-Saharan Africa.hese pathogens can cause pneumonia or urinary tract infection and may be involved in coronary heart disease. Other groups of intacellular bacterial pathogens include: Salmonella, Neisseria, Brucella, Mycobacterium, Listeria, Francisella, Legionella, and Yersinia pestis.