Below is the chemical reaction for the formation of calcium chloride: Calcium chloride salts can also form crystals based on these same ionic properties. Positive calcium ions can orient themselves so that they are close to the negative chloride ions in another molecule.
Neurofibrillary Tangles (NFTs) are aggregates of hyperphosphorylated tau protein that are most commonly known as a primary marker of Alzheimer's Disease.Their presence is also found in numerous other diseases known as tauopathies.ormation [edit]. Neurofibrillary tangles are formed by hyperphosphorylation of a microtubule-associated protein known as tau, causing it to aggregate, or group, in an insoluble form.
Tauopathies are a class of neurodegenerative diseases associated with the pathological aggregation of tau protein in the human brain. The best-known of these illnesses is Alzheimer's disease (AD), wherein tau protein is deposited within neurons in the form of neurofibrillary tangles (NFTs).They were first described by the eponymous Alois Alzheimer in one of his patients suffering from the disorder.These aggregations of hyperphosphorylated tau protein are also referred to as PHF, or  paired helical filaments ). The precise mechanism of tangle formation is not completely understood, and it is still controversial as to whether tangles are a primary causative factor in the disease or play a more peripheral role.