FDAâs Breakthrough Therapy Designation. The Breakthrough Therapy Designation (BTD) came into force in July 2012 after the Food and Drug Administration Safety and Innovation Act (FDASIA) was approved by Congress.
SoBe (stylized as SoBE) is an American brand of teas, fruit-juice blends and enhanced water beverages owned by PepsiCo. The name SoBe is an abbreviation of South Beach, named after the upscale area located in Miami Beach, Florida. In the past, the SoBe name has also been licensed for gum and chocolate products. SoBe switched from glass bottles to plastic bottles for all of its beverages in 2010.
In Okinawa, soba usually refers to Okinawa soba, a completely different dish of noodles made out of flour, not buckwheat. Okinawa soba is also quite popular in the city of Campo Grande (Brazil), due to influence of Japanese (Okinawan) immigrants. It is eaten at street markets or in special restaurants called sobarias.he most famous Japanese soba noodles come from Nagano. Soba from Nagano is called Shinano Soba or Shinshu soba. Ni-hachi (äºå«, two-eight) soba, consists of two parts of wheat and eight of buckwheat; Juwari (åå², 100%) soba, the finest (and usually most expensive) variety, consists entirely of buckwheat.