In other words: A Permutation is an ordered Combination. There are basically two types of permutation: 1  Repetition is Allowed: such as the lock above. It could be 333.  No Repetition: for example the first three people in a running race. You can't be first and second.
For this reason, the idea that collagen supplementation can be an effective treatment for joint pain, osteoarthritis, or any other condition, is highly implausible, if not impossible in principle.
Vitamin C, an antioxidant that often works with glutathione, may inhibit the bone destroying osteoclasts and sustain the growth of the bone building osteoblasts, by mechanisms such as upregulating collagen type I synthesis. Collagen synthesis is also essential for bone fracture healing in and of itself.