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Gluconeogenesis is a pivotal biochemical pathway in which glucose is synthesised from nonâcarbohydrate precursors, that is, lactate, alanine, glutamine and glycerol, during prolonged starvation.
Glucagon is secreted when blood sugar is low. It triggers gluconeogenesis in the liver, which means that fats and proteins are converted into glucose and released into the blood. It also is responsible for mobilizing glycogen stores, suppresses insulin, and mobilizes fat stores.