Marketed as Aclasta (in Australia) or Reclast (in the US), zoledronic acid may be given as a 5 mg infusion once per year for treatment of osteoporosis in men and post-menopausal women at increased risk of fracture.
Portsmouth was part of the Triangle Trade, which made significant profits from slavery. At the town's incorporation in 1653, it was named Portsmouth in honor of the colony's founder, John Mason. He had been captain of the port of Portsmouth, England, in the county of Hampshire, for which New Hampshire is named.
New Hampshire's state motto is Live Free or Die. The motto comes from a statement written by the Revolutionary General John Stark, hero of the Battle of Bennington. As leaders in the revolutionary cause, New Hampshire delegates received the honor of being the first to vote for the Declaration of Independence on July 4, 1776.