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Main areas affected by nodular acne are the face and back, but it can also occur on other parts of the body such as the neck, chest, upper arms, shoulders, and buttocks, ranging from just a few breakouts to more widespread blemishes.
But nodules happen deeper in the skin, and are more serious form of blemish than a papule. They happen when their is a deep break in the follicle wall and the infected material spills into the dermis. Acne nodules take a lot longer to heal than papules, too. Even the largest papules heal within just a few weeks.