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Definition of node 1 a: a pathological swelling or enlargement (as of a rheumatic joint) b: a discrete mass of one kind of tissue enclosed in tissue of a different kind
Lymph node: One of many small, bean-shaped organs located throughout the lymphatic system. The lymph nodes are important in the function of the immune response and also store special cells that can trap cancer cells or bacteria that are traveling through the body through the lymph. Also known as lymph gland.