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Summary Information: Valve Cusps Valve Cusps: Valve cusps are located in the valves of the heart and are flaps of tissue that open in one direction as blood is pumped through them. The valve cusps are made of thin fibrous tissue, covered with a smooth membrane (endocardium) and reinforced by connective tissue.
Full Heart Description. [Continued from above] . . . pulmonary arteries and veins, and the vena cava. The inferior tip of the heart, known as the apex, rests just superior to the diaphragm. The base of the heart is located along the bodyâs midline with the apex pointing toward the left side. Because the heart points to the left, about 2/3 of the heartâs mass is found on the left side of the body and the other 1/3 is on the right.