A backfire is when the ignition of fuel doesn't take place in the ignition/combustion chamber, it(a backfire) can take place in the intake or exhaust. It can â¦ be caused by a fuel to air ratio not being correct, also if the timing of the spark is not just right that could cause it to back fire.
Melanoma in the United States. From 2005 to 2009, the median age at diagnosis for melanoma of the skin was 61, and the median age at death was 68. The age-adjusted incidence rate was 21.0 per 100,000 men and women per year.
Being such a late stage melanoma, the metastatic stage has a 10-year survival rate of less than 10% (NIH 2009), with a life expectancy of 2-7 months, depending on the number of organs the cancer has spread to (Treatment Trials 2010).