HHNKC is also known as diabetic hyperglycemic hyperosmolar coma (HHOC), hyperosmolar nonketotic coma (HONK), hyperosmolar hyperglycemic state (HHS) or hyperosmolar hyperglycemic nonketotic syndrome (HHNS). In HHNKC, blood sugar levels rise, and your body tries to get rid of the excess sugar by passing it into your urine.
Pressures sores result from the death (necrosis) of tissues due to local deprivation of blood supply, and thus of oxygen (ischemic necrosis). This is why tissue compression is the first clinical sign of pressure sores; it blocks the small blood vessels supplying tissues.
necrosis. Death of some or all cells in an organ or tissue. The process involves swelling of the nucleus (pyknosis), fragmentation of the nucleus (karyorrhexis) and complete dissolution of the nuclear chromatin (karyolysis).Necrosis is caused by disease, trauma or interference with blood supply.he death of cells, a portion of tissue, or a portion of an organ due to permanent damage of some sort, such as a lack of oxygen supply to the tissues.