A 130-pound golfer who golfs with the use of a power cart burns 207 calories per hour, according to the Wisconsin Department of Health and Family Services. As a person's body weight increases, so too does his caloric burn. In an hour, a 190-pound person burns 302 calories golfing with a power cart. Swapping your power cart in favor of pulling your clubs increases your caloric burn. A 130-pound person burns 295 calories per hour of golfing while pulling his or her clubs.
Mechanism of action: Cyclophosphamide is an inactive drug. With the help of cytochrome P-450 oxidase system in the liver, the inactive drug is converted into phosphoramide mustard and acrolein which are very active compounds. Phosphoramide mustard has an ability to introduces alkyl radicals into DNA strands with interferes DNA replication by forming DNA cross-linkage. Cross-linked cancer cell DNA is unable to complete normal cell division. Thus, it stops cancer cells from growing, causing them to die.
Cyclins go hand in hand with kinases. Cyclins do not cause a cell to progress in the cell cycle because cyclins are mere proteins that regulate the rate of the process, and how fast the cell progresses through this process. Cyclins also act by binding to various kinases, which are enzymes that transfer a phosphate group from ATP to other enzymes. The phosphate group activates these enzymes. The quantity of these kinases in the cell remains steady throughout the cell cycle; however they are active only when bound to cyclins.