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1. stoichiometry - (chemistry) the relation between the quantities of substances that take part in a reaction or form a compound (typically a ratio of whole integers).
An equivalent statement is the law of constant composition, which states that all samples of a given chemical compound have the same elemental composition by mass. For example, oxygen makes up about 8 / 9 of the mass of any sample of pure water, while hydrogen makes up the remaining 1 / 9 of the mass. Along with the law of multiple proportions, the law of definite proportions forms the basis of stoichiometry.