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Definition of node 1 a: a pathological swelling or enlargement (as of a rheumatic joint) b: a discrete mass of one kind of tissue enclosed in tissue of a different kind
Biology. an unattached cell, especially of a kind that floats freely, as a blood or lymph cell. Anatomy. a small mass or body forming a more or less distinct part, as the sensory receptors at nerve terminals. Physical Chemistry. a minute or elementary particle of matter, as an electron, proton, or atom.