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Spirillum. a genus of gram-negative, spiral, and curved bacteria, including one species, S. miÂ´nus, that is pathogenic for guinea pigs, rats, mice, and monkeys and is the cause of rat-bite fever in humans.piÂ·rilÂ·la. A member of the genus Spirillum. /SpiÂ·rilÂ·lum/ (spi-rilÂ´um) a genus of gram-negative bacteria. The species S. miÂ´nus is pathogenic for guinea pigs, rats, mice, and monkeys and is the cause of rat-bite fever (sodoku) in humans.
Description and Significance. Spirillum bacteria are thought to have been first described by van Leeuwenhoek in the 1670s and later by Muller. S. volutans is a large bacterium as well as an obligate microaerophile with a helical structure.ell Structure and Metabolism. Spirillum bacteria are large chemotrophic spirilla 1.4 to 1.7 micrometers in diameter and up to 60 micrometers in length, with anywhere from less than one to five helical turns.