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1. stoichiometry - (chemistry) the relation between the quantities of substances that take part in a reaction or form a compound (typically a ratio of whole integers).
Stoichiometry is the method by which we calculate how many grams of these reactants are needed to form a given amount of product in a chemical reaction. Stoichiometry is basically the same as a recipe for cooking enchiladas. How many moles of O2 are required to burn 0.5 moles of CH4? 1 CH4 + 2 O2  CO2 + 2 H2O. The 1 in front of the CH4 is for clarity in the solution of this problem and is not normally shown.