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Famous People with Cystic Fibrosis. 7 Famous People with Cystic Fibrosis. Lisa Bentley is a world-renowned Canadian triathlon athlete and was diagnosed with a cystic fibrosis in her 20s. She has 20 Ironman titles under her belt, and continues to work hard despite her condition.
Abstract. The most common cystic fibrosis transmembrane conductance regulator (CFTR) mutant in cystic fibrosis patients, Î´F508 CFTR, is retained in the endoplasmic reticulum (ER) and is consequently degraded by the ubiquitin-proteasome pathway known as ER-associated degradation (ERAD).