FDAâs Breakthrough Therapy Designation. The Breakthrough Therapy Designation (BTD) came into force in July 2012 after the Food and Drug Administration Safety and Innovation Act (FDASIA) was approved by Congress.
SoBe (stylized as SoBE) is an American brand of teas, fruit-juice blends and enhanced water beverages owned by PepsiCo. The name SoBe is an abbreviation of South Beach, named after the upscale area located in Miami Beach, Florida. In the past, the SoBe name has also been licensed for gum and chocolate products. SoBe switched from glass bottles to plastic bottles for all of its beverages in 2010.
South Beach (also known as SoBe, or simply the Beach), the area from Biscayne Street (also known as South Pointe Drive) one block south of 1st Street to about 23rd Street, is one of the more popular areas of Miami Beach. Topless sunbathing by women is illegal, but is officially tolerated on South Beach.