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1. stoichiometry - (chemistry) the relation between the quantities of substances that take part in a reaction or form a compound (typically a ratio of whole integers).
also stoiâ¢cheiâ¢omâ¢eâ¢try. 1. the calculation of the quantities of chemical elements or compounds involved in chemical reactions. 2. the branch of chemistry dealing with relationships of combining elements, esp. quantitatively. stoicheio(stoicheÃ®o) n (element derivative of stoichos, stoÃ®chos; row file akin to) + -stichos ]. stÃ­chos stich metry