manifest. 1  readily perceived by the eye or the understanding; evident; obvious; apparent; plain: a manifest error. 2  Psychoanalysis. of or relating to conscious feelings, ideas, and impulses that contain repressed psychic material: the manifest content of a dream as opposed to the latent content that it conceals.
In medicine, an adverse effect is an undesired harmful effect resulting from a medication or other intervention such as surgery. An adverse effect may be termed a  side effect , when judged to be secondary to a main or therapeutic effect.
There are three main types of antiepileptic medication side effects. Some mild side effects are common when starting antiepileptic medications, particularly if the dose is increased rapidly. These include nausea, abdominal pain, dizziness, sleepiness, irritability, anxiety or mood changes.