In other words: A Permutation is an ordered Combination. There are basically two types of permutation: 1  Repetition is Allowed: such as the lock above. It could be 333.  No Repetition: for example the first three people in a running race. You can't be first and second.
For this reason, the idea that collagen supplementation can be an effective treatment for joint pain, osteoarthritis, or any other condition, is highly implausible, if not impossible in principle.
Collagen supplements help with healing and repairing damaged bones and cartilages. Collagen is a family of fibrous proteins that act as the building blocks for skin, bones, teeth, cartilage, tendons and other connective tissues, according to the National Institute of Arthritis and Musculoskeletal and Skin Diseases.