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Psychologically disturbed children who bite and suck their fingers cause thickenings that resemble knuckle pads to occur in the skin in the traumatized areas. Patients with bulimia who use their knuckles or fingers to induce emesis sometimes develop fibrotic papules resembling knuckle pads. [8] Some cases of knuckle pads are familial.
PAD is a circulatory condition that causes narrowing of the blood vessels and arteries. In an associated condition called atherosclerosis, arteries stiffen due to plaque buildup in the arteries and blood vessels. Both conditions decrease blood flow to your extremities and can result in pain. Over time, reduced blood flow in your extremities can cause: numbness; tingling; nerve damage; tissue damage; If left untreated, reduced blood flow and plaque in your carotid arteries may result in a stroke. Your carotid arteries are the major blood vessels that deliver blood to your brain. If plaque buildup takes place in the arteries in your heart, youâre at risk of having a heart attack.