Hangouts is integrated with Googleâs cloud-based office suite, which is known as Google Apps for Work. While most Google Apps are free, businesses with paid accounts get additional features with services such as Gmail and Google Drive.
Melanosis coli is a condition usually associated with chronic laxative use in which dark pigment is deposited in the lamina propria (one of the lining layers) of the large intestine (colon). The pigment deposition results in a characteristic dark brown to black discoloration of the lining of the large intestine.
Anthraquinones have a direct toxic effect on the epithelial cells of the colon that results in the production of lipofuscin, the dark pigment seen in macrophages in melanosis coli (Panel C, arrow). The cecum and rectum are the most common sites of melanosis coli, but it can affect the entire large bowel.