The leading modifiable risk factors worldwide are: 1  tobacco smoking, which is strongly associated with lung cancer, mouth, and throat cancer; 2  drinking alcohol, which is associated with a small increase in oral, esophageal, breast, liver and other cancers; 3  a diet low in fruit and vegetables,
Trier Tourism: Best of Trier. Trier, Germany. Trier, which lies in the Moselle wine region along the banks of the Moselle River, is the oldest city in Germany. The city is home to the University of Trier.
The Lower or Rhenish Palatinate which was also called the Pfalz was located in southwest Germany east of Luxembourg along both sides of the Middle Rhine River. The Pfalz included the present German States of Mainz, Treves, Lorraine, Alsace, Baden and Wurtemberg.Heidelberg was its capital.he Lower or Rhenish Palatinate which was also called the Pfalz was located in southwest Germany east of Luxembourg along both sides of the Middle Rhine River. The Pfalz included the present German States of Mainz, Treves, Lorraine, Alsace, Baden and Wurtemberg. Heidelberg was its capital.