Definition of sociopolitical. : of, relating to, or involving a combination of social and political factors.
Beta-1 receptors are found in the heart, and when stimulated will increase herat rate and cardiac contractility. Beta-2 receptors are found on vascular smooth muscle located in the heart and skeletal muscle, and when they are activated, they dilate and decrease SVR.
The pathogenesis of vasomotor symptoms such as hot flashes is unknown, but serotonin receptors are felt to play a role, and serotonin inhibitors such as fluoxetine and paroxetine and the bi-cyclic antidepressant, venlafaxine, have been demonstrated to improve hot flashes in survivors of breast cancer.