Thienopyridines, a class of oral antiplatelet agents, permanently inhibit P2RY12 signaling, which is sufficient to block platelet activation. F2R, TBXA2R and P2RY1 couple to the Gq-PLC-IP3-Ca2+ pathway, inducing shape change and platelet aggregation.
On April 1, 2001, the Austrian Regulatory Authority for Broadcasting and Telecommunications (RTR) was established under Austrian law.
The recovery time objective (RTO) is the maximum tolerable length of time that a computer, system, network, or application can be down after a failure or disaster occurs. The RTO is a function of the extent to which the interruption disrupts normal operations and the amount of revenue lost per unit time as a result of the disaster. These factors in turn depend on the affected equipment and application(s).