Hedges against a white fence. noun. The definition of a hedge is a boundary or fence formed by closely planted bushes or trees. An example of hedge is a line of bushes planted close together creating a border. Hedge is defined as something you do to minimize loss.
Drugs do not enter the breast milk directly from the motherâs blood. It enters the milk indirectly through the mothersâ breast tissue. During the first two weeks postpartum, medications may reach their highest concentration in the milk.
The amount of drug excreted into milk depends on a number of kinetic factors: 1) the lipid solubility of the drug, 2) the molecular size of the drug, 3) the blood level attained in the maternal circulation, 4) protein binding in the maternal circulation, 5) oral bioavailability in the infant, and the mother, and.