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This is the third form of hypersensitivity in the Gell-Coombs classification, called Type III hypersensitivity. Immune complex deposition is a prominent feature of several autoimmune diseases, including systemic lupus erythematosus, cryoglobulinemia, rheumatoid arthritis, scleroderma and SjÃ¶gren's syndrome.
Rheumatoid arthritis symptoms may flare in response to specific proteins found in dairy products. Some people with rheumatoid arthritis who report intolerance to milk have antibodies to milk proteins, Dr. Michet said.