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Catalog No.S4186. Domiphen bromide is a quaternary ammonium antiseptic with actions as a cationic surfactant.In vitro. Recombinant 4-diphosphocytidyl-2-C-methyl-d-erythritol synthase (IspD) is sensitive to Domiphen Bromide (DMB), as observed through an IspD activity assay.The inhibitory effect of DMB on IspD is confirmed by both the newly-established high-throughput screening system and traditional enzyme kinetic assays.omiphen bromide is a quaternary ammonium antiseptic with actions as a cationic surfactant. In vitro. Recombinant 4-diphosphocytidyl-2-C-methyl-d-erythritol synthase (IspD) is sensitive to Domiphen Bromide (DMB), as observed through an IspD activity assay.
Medical uses. Pyridostigmine is used to treat muscle weakness in people with myasthenia gravis or forms of congenital myasthenic syndrome and to combat the effects of curariform drug toxicity. Pyridostigmine bromide has been FDA approved for military use during combat situations as an agent to be given prior to exposure to the nerve agent soman in order to increase survival.