The skin involvement of dermatomyositis is absent in polymyositis. Dysphagia (difficulty swallowing) or other problems with esophageal motility occur in as many as 1/3 of patients. Low grade fever and peripheral adenopathy may be present.
In 1524, Michelangelo was commissioned by the Medici pope to design the library for the San Lorenzoâs Church in Florence, Italy. Michelangelo designed both the interior of the library itself and its vestibule. He pioneered the Mannerist style in his design of the library which became renowned for its architecture. The Laurentian Library is one of Michelangeloâs most important architectural achievements and his innovations and use of space in the library were revolutionary.
The Sistine Chapel ceiling, painted by Michelangelo between 1508 and 1512, is a cornerstone work of High Renaissance art. The ceiling is that of the Sistine Chapel, the large papal chapel built within the Vatican between 1477 and 1480 by Pope Sixtus IV, for whom the chapel is named. It was painted at the commission of Pope Julius II. The chapel is the location for papal conclaves and many other important services.