1 Blockage in a coronary artery during or after a heart attack. 2  Blockage or narrowing of one or more coronary arteries that puts you at risk for a heart attack.  Narrowings that reduce blood flow and cause persistent chest pain (angina) that medicines do not control.
Harold Frederick Shipman (14 January 1946 â 13 January 2004) was a British doctor and one of the most prolific serial killers in recorded history.
Herman Mudgett, byname H.H. Holmes (born May 16, 1861?, Gilmanton, N.H., U.S.âdied May 7, 1896, Philadelphia, Pa.), American swindler and confidence trickster who is widely considered the countryâs first known serial killer. 1  Mudgett was born into a wealthy family and showed signs of high intelligence from an early age. Always interested in medicine, he allegedly trapped animals and performed surgery on them; some accounts of his life even suggest that he killed a childhood playmate.