Members of the DEWS Definition and Classification. Subcommittee developed a contemporary definition of dry eye disease and a three-. part classification system based on etiology, causative mechanisms and disease. severity.
Metaplasia. Definition: Metaplasia is the reversible replacement of one differentiated cell type with another differentiated cell type. Metaplasia causes precursor cells to change their cell fate, and do not change existing differentiated cells.he most common epithelial metaplasia is columnar to squamous (squamous metaplasia), as occurs in the respiratory tract in response to chronic irritation.
myeloid metaplasia a syndrome characterized by myeloid tissue in extramedullary sites with nucleated erythrocytes and immature granulocytes in the circulating blood and extramedullary hematopoiesis in the liver and spleen, as well as anemia and splenomegaly.