Also, be sure to see the Game of Thrones Characters chart, here. Below is a simpler chart focusing only on the four main families. It primarily shows the royal bloodline with all the claimants and possible claimants, including popular fan theories (SPOILERS!). Click it to enlarge.
Contact with blood proteins â about 98%. Excretion of plasma takes place in two phases, with a finite half-life 19-22 hours, allowing to take the drug once daily. Doxazosin is side effects of tamoxifen extensively metabolized in the liver by demethylation of hydroxylation and, in patients with impaired liver function, as well as the reception drugs that can alter hepatic metabolism, the process can break down the drug biotransformation.
Tamoxifen is a selective estrogen receptor modulator. Even though it is an antagonist in breast tissue it acts as partial agonist on the endometrium and has been linked to endometrial cancer in some women. Therefore endometrial changes, including cancer, are among tamoxifen's side effects. With time, risk of endometrial cancer may be doubled to quadrupled, which is a reason tamoxifen is typically only used for 5 years.