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Addisonâs disease most commonly affects female dogs around four or five years old. This condition is typically caused by injury to the adrenal glandsâ tissue from infection, hemorrhaging, or autoimmune disorders. If your pet is coming off of steroid treatment, the steroid withdrawal may also be causing an imbalance.
Story at-a-glance 1  +. Addisonâs disease, also known as hypoadrenocorticism, is a condition in which the adrenal glands donât produce the amount of hormones a dogâs body requires. 2  The adrenal glands secrete the hormones responsible for the âfight-or-flightâ response in animals.