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An underactive thyroid gland, a disorder called hypothyroidism, would cause a sensation of lump in the throat. General enlargement, nodules and inflammation in the thyroid gland can be caused by both hypo as well as hyperthyroidism. These nodules can cause a feeling of lump in the throat. Diagnosis usually rests on physical examination, blood tests, a needle biopsy and possibly an ultra sound examination.
Lump in the Neck: Not all thyroid nodules are big enough to cause a noticeable lump. Some people, though, may notice a lump in the front of their neck. You may be able to see it, or perhaps you can't see it but you can feel it. Other people may notice a lump in your neck when you swallow.