Do not take more than your recommended dose. An Advil overdose can damage your stomach or intestines. The maximum amount of ibuprofen for adults is 800 milligrams per dose or 3200 mg per day (4 maximum doses). Use only the smallest amount of ibuprofen needed to get relief from your pain, swelling, or fever. A child's dose of ibuprofen is based on the age and weight of the child.
High doses of common pain drugs NSAIDs can cause heart attack: study. NSAIDs increase blood pressure and likelihood of clotting, which can wreak havoc for your heart, the authors of a new study note. High doses of some commonly used pain drugs like ibuprofen can increase heart attacks, strokes and related deaths by about a third, a study warned on Thursday. The drugs, known as non-steroidal anti-inflammatory drugs (NSAIDs), are widely used to manage pain caused by inflammatory disorders.
The terrible consequences of this trend include overdose deaths, which have more than quadrupled in the past decade and a half. The causes are complex, but they include overprescription of pain medications. In 2013, 207 million prescriptions were written for prescription opioid pain medications. Stimulants can have strong effects on the cardiovascular system. Taking high doses of a stimulant can dangerously raise body temperature and cause irregular heartbeat or even heart failure or seizures. Also, taking some stimulants in high doses or repeatedly can lead to hostility or feelings of paranoia.