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A number of different diseases can result in glomerular disease. It may be the direct result of an infection or a drug toxic to the kidneys, or it may result from a disease that affects the entire body, like diabetes or lupus. Many different kinds of diseases can cause swelling or scarring of the nephron or glomerulus.he signs and symptoms of glomerular disease include. 1  proteinuria: large amounts of protein in the urine. 2  hematuria: blood in the urine. 3  reduced glomerular filtration rate: inefficient filtering of wastes from the blood. 4  hypoproteinemia: low blood protein. 5  edema: swelling in parts of the body.
IgA nephropathy, also known as Berger's disease, is caused by inflammation of the glomeruli. Blood and protein go into the urine due to waste filtration not functioning correctly. Symptoms include high blood pressure, blood in the urine, pain in the sides, edema and flu-like symptoms among other things.ver time, inflammation leads to scarring in the glomeruli, which can sometimes lead to chronic kidney disease (CKD) or end stage renal disease (ESRD) . Symptoms of MPGN include blood in the urine, swelling around the stomach, eyes, feet and legs and fluid retention.