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Q: How often do doctors give cortisone injections to a patient? A: We try to limit the injection to one every three months for any single joint, but also we like to limit it to a total of six injections a year for the whole body. We know that the cortisone can sometimes weaken or suppress the immune system and, in diabetics, it raises blood sugar.
The cortisone flare usually only lasts a day or two after the shot is administered and can be treated by icing the area of the shot. It is also common for the area around the shot to whiten in appearance. More serious side effects are rare, but do occasionally occur.