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Trypophobia Definition. There are thousands of people who claim they have the Trypophobia (fear of holes in the skin). However, It is not recognized in the American Psychiatric Associationâs Diagnostic and Statistical Manual of Mental Disorders (DSM) or other scientific literature.
Facies in autoimmune disease. 1  Face in scleroderma: Scleroderma patients has the following characteristic facies.Skin over the face is taut and shiny. Patient finds it difficult to in open his mouth or to smile (microstomia). 2  Face in SLE: SLE is a disease predominantly in women.