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Genital skin irritation in preschool-aged girls usually is caused by poor hygiene. Irritation of the skin around the vagina or the urethra may cause a burning pain when urine touches the irritated skin.Pain from genital skin irritation occurs more frequently in women and girls than it does in men and boys.enital skin irritation in preschool-aged girls usually is caused by poor hygiene. Irritation of the skin around the vagina or the urethra may cause a burning pain when urine touches the irritated skin.
Yellowing of the skin and eyes, dark urine and light stools appear as the bile levels climb, often accompanied by widespread itching. Bile flow obstruction can occur inside the liver -- for example, due to hepatitis, cirrhosis, drug use or pregnancy; or it can occur outside the liver, due to gallstones, tumors or inflammation of the pancreas.