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An underactive thyroid gland, a disorder called hypothyroidism, would cause a sensation of lump in the throat. General enlargement, nodules and inflammation in the thyroid gland can be caused by both hypo as well as hyperthyroidism. These nodules can cause a feeling of lump in the throat. Diagnosis usually rests on physical examination, blood tests, a needle biopsy and possibly an ultra sound examination.
1 Lump in the Neck: Not all thyroid nodules are big enough to cause a noticeable lump. 2  Some people, though, may notice a lump in the front of their neck. 3  You may be able to see it, or perhaps you can't see it but you can feel it.4  Other people may notice a lump in your neck when you swallow.he above symptoms are associated with thyroid nodules of all types, not just cancerous nodules. Since most thyroid cancers develop in thyroid nodules, it's essential to be aware of these symptoms and signs that may point to thyroid cancer.