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Full Definition of DIPHTHERIA. : an acute febrile contagious disease typically marked by the formation of a false membrane especially in the throat and caused by a gram-positive bacterium (Corynebacterium diphtheriae) that produces a toxin causing inflammation of the heart and nervous system.
Diphtheria is an infection caused by the bacterium Corynebacterium diphtheriae. Diphtheria causes a thick covering in the back of the throat. It can lead to difficulty breathing, heart failure, paralysis, and even death. Vaccines are recommended for infants, children, teens and adults to prevent diphtheria.