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Genital skin irritation in preschool-aged girls usually is caused by poor hygiene. Irritation of the skin around the vagina or the urethra may cause a burning pain when urine touches the irritated skin.Pain from genital skin irritation occurs more frequently in women and girls than it does in men and boys.enital skin irritation in preschool-aged girls usually is caused by poor hygiene. Irritation of the skin around the vagina or the urethra may cause a burning pain when urine touches the irritated skin.
However, dark brown urine can also be a sign of rare side effects (liver problems or anemia). Therefore, seek immediate medical attention if you notice dark urine along with any of the following symptoms: persistent nausea/ vomiting, stomach / abdominal pain, yellowing eyes / skin, tiredness, fast/pounding heartbeat. very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching /swelling (especially of the face/ tongue /throat), severe dizziness, trouble breathing.