Definition of sociopolitical. : of, relating to, or involving a combination of social and political factors.
Beta-1 receptors are found in the heart, and when stimulated will increase herat rate and cardiac contractility. Beta-2 receptors are found on vascular smooth muscle located in the heart and skeletal muscle, and when they are activated, they dilate and decrease SVR.
*NOTE: The MC2-R receptor system looks and works similarly to the beta-2 adrenergic receptor system, which initiates relaxation of the bronchiole muscle cells (seen later in the movie) when epinephrine binds to it. When it binds, ACTH stimulates the receptor to change shape. This conformational change causes the G protein complex to become activated and uncoupled. When the G protein stimulates it, Adenylate cyclase converts ATP (the cell's energy molecule) into cAMP (a signaling molecule).