The cost per page is calculated based on the cost per ink cartridge and the average number of pages per cartridge, based on the 20% coverage model.
It is named after John Langdon Down, the British doctor who fully described the syndrome in 1866. Some aspects of the condition were described earlier by Jean-Ãtienne Dominique Esquirol in 1838 and Ãdouard SÃ©guin in 1844. In 1957, the genetic cause of Down syndrome, an extra copy of chromosome 21, was discovered.
âThese were really exciting finds.â. Sir John Franklin set out from England on May 19, 1845, on a mission to find the Northwest Passage through the Arctic. He had two Royal Navy ships â the HMS Erebus and the HMS Terror â a crew of 135, and provisions for what was expected to be a three-year journey.