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The normal lipase level is 12-70 U/L. Normal values may vary from laboratory to laboratory. Causes of hyperlipasemia (high lipase levels) may include: Pancreatitis - also known as inflammation of the pancreas, can cause amylase and lipase levels to be increased up to 3 times normal. Both values should be increased, in order to carry the diagnosis of pancreatitis.
*A high lipase level usually indicates inflammation, injury, or blocked drainage of the pancreatic enzymes. Very high lipase levels usually indicate pancreatitis or blockage of the tube (duct) leading from the pancreas to the beginning of the small intestine (duodenum). * High lipase levels may indicate damage to the pancreas caused by a stomach ulcer that has eroded, or perforated, the wall of the stomach.