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Tobacco would be the salvation not only of Jamestown but of the  state of Virginia. Tobacco remain a profitable case crop in the  region until the negative campaign against â¦the tobacco industry  decreased the demand.
Jamestown served as the Colony of Virginia's capital from 1616 to 1699. Between 1609 and 1610 approximately 80% of the colonists at Jamestown died from starvation and disease. Although Jamestown was the first successful permanent English settlement in the United States, it wasn't the first permanent settlement. The Spanish founded St. Augustine in Florida in 1565.