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De Quervain's tenosynovitis is inflammation of tendons on the side of the wrist at the base of the thumb. These tendons include the extensor pollicis brevis and the abductor pollicis longus tendons, which extend the joints of the thumb. De Quervain's tenosynovitis can be brought on by simple strain injury to the extensor pollicis longus and abductor pollicis tendons (tendinitis). Often this form of tendinitis is a result of repetitive motion injury.
This is also known as de Quervain's tendinosis. It causes pain on the thumb side of the wrist. The pain may develop gradually or suddenly. It can travel the length of the thumb and up the forearm. If you have de Quervain's tendinitis, movements that can be painful include: 1  Making a fist. 2  Grasping or holding objects. 3  Turning the wrist.