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Wernicke-Korsakoff syndrome (WKS) is a type of brain disorder caused by a lack of vitamin B1. The syndrome is actually two separate conditions that can occur at the same time.Usually youâll experience symptoms of Wernickeâs encephalopathy first.igns of Korsakoff psychosis tend to follow as the Wernickeâs symptoms wane. If Wernickeâs disease is treated quickly and effectively, Korsakoff syndrome may not develop (Mayo Clinic). Korsakoff psychosis is the result of chronic brain damage. Korsakoff syndrome affects the areas of your brain that control memory.
Because the chronic memory loss of Korsakoff syndrome often follows an episode of Wernicke encephalopathy, the chronic disorder is sometimes known as Wernicke-Korsakoff syndrome. But Korsakoff syndrome can also develop in individuals who have not had a prior episode of Wernicke encephalopathy.