Members of the DEWS Definition and Classification. Subcommittee developed a contemporary definition of dry eye disease and a three-. part classification system based on etiology, causative mechanisms and disease. severity.
Metaplasia. Definition: Metaplasia is the reversible replacement of one differentiated cell type with another differentiated cell type. Metaplasia causes precursor cells to change their cell fate, and do not change existing differentiated cells.he most common epithelial metaplasia is columnar to squamous (squamous metaplasia), as occurs in the respiratory tract in response to chronic irritation.
Focal intestinal metaplasia is the potentially reversible change from a fully differentiated stomach cell type to an intestinal cell type. It is associated with significantly increased risk of cancer. . Metaplasia is the potentially reversible change from a fully differentiated cell type to another cell type. Metaplasia is associated with significantly increased risk of cancer. Therefore, it is defined as a precancerous condition. Metaplasia can occur in a variety of the bodyâs tissues. However, it is most commonly found in the stomach or intestines.