Some birth defects are caused by a mutation (change) in a single gene. In 1991, Stephen Warren, PhD, a March of Dimes grantee at Emory University in Atlanta, Georgia, identified the gene that causes fragile X syndrome, the most common inherited cause of intellectual disabilities.
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These symptoms are most prominent when individuals go from the lying or sitting position to the standing position (orthostatic hypotension). Low blood pressure that causes an inadequate flow of blood to the body's organs can cause strokes, heart attacks, and kidney failure. It's most severe form is shock. Common causes of low blood pressure include a reduced volume of blood, heart disease, and medications.