1 Examples are morphine and heroin. 2  Worldwide, an estimated 69 000 people die from opioid overdose each year.  There are an estimated 15 million people who suffer from opioid dependence (i.e. an addiction to opioids).
Berberine is a natural alkaloid found in a wide variety of traditional herbs including goldenseal, barberry and Oregon grape. Many herbalists credit this unique alkaloid for the benefits of ancient herbal tonics used by native populations throughout the world.
Oregon Grape: The Poor Manâs Goldenseal is a Rich Source of Berberine. Springtime: daffodils nod on the hillsides, chickadees launch their three-note arias from the underbrush, overflying Canada geese honk into the chilly wind, and orchard mason bees vibrate within the goblet-shaped, lemon-yellow blossoms of Oregon grape.