1 To establish the maximum tolerable dose of betahistine dihydrochloride (betahistine) within the range of 50 mg to 300 mg/day that appears to be effective for atypical depression. Are at significant risk of suicide as indicated by a score of 3 or greater on item number 11 on the HAM-D 28. 2  Have received any investigational product within 28 days of Screening. 3  Have used any antidepressant within 7 days of Screening (14 days for MAOIs; 21 days for fluoxetine).
Boulder Creek, California. Boulder Creek is a census-designated place (CDP) in Santa Cruz County, California, with a population of 4,923 as of the 2010 census.
Fossil Creek is within the Verde River Watershed. Its headwaters are fed by Fossil Springs, which are located about 5 miles west of Strawberry, Arizona. From the springs, on floor of the remote and ruggedly scenic Fossil Creek Canyon, you look nearly straight up about 1,600 feet to the top of the Mogollon Rim.