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This is termed the albumin/creatinine ratio (ACR) and microalbuminuria is defined as ACR â¥3.5 mg/mmol (female) or â¥2.5 mg/mmol (male), or, with both substances measured by mass, as an ACR between 30 and 300 Âµg albumin/mg creatinine.
For example if the spot urine protein is 300 mg / dl and spot urine creatinine is 150 mg / dl, the ratio will be 300 / 150 = 2 which means 24 hours urine protein excretion is 2 gram. Use of single voided urine prot/creat ratio as an alternative to 24 hours urine collection was suggested first in 1980s 6,7.