Clinical Effects on the Peripheral Nervous System Due to Excessive Stimulation of Muscarinic Receptors. Excessive Stimulation of muscarinic receptors due to cholinesterase inhibitor poisoning results in increased parasympathetic: (Erdman 2004). 1  Cardiac effects.
A myofibril (also known as a muscle fibril) is a basic rod-like unit of a muscle cell. Muscles are composed of tubular cells called myocytes, known as muscle fibers in striated muscle, and these cells in turn contain many chains of myofibrils.he filaments of myofibrils, myofilaments, consist of two types, thick and thin: 1  Thin filaments consist primarily of the protein actin, coiled with nebulin filaments.
Looking at one muscle fiber, you will see that almost the entire cross section of the muscle fiber is taken up by long, cylindrical strands of contractile proteins called myofibrils. Typically there are hundreds of these in one cross section of a muscle fiber.ooking at one myofibril, we see that it is divided into segments called sarcomeres. These are the contractile units of a muscle. A dark stripe called a Z disc marks the ends of one sarcomere and the beginning of the next. Sarcomeres are composed of thick filaments and thin filaments.