These studies are now being done by GWAS in 2 patient groups, examining both baseline HbF and the HbF response to hydroxyurea. Genetic modulation of sickle cell disease: Homozygosity for a single Î²-globin gene mutation (HBB; glu6val) causes sickle cell anemia.hese studies are now being done by GWAS in 2 patient groups, examining both baseline HbF and the HbF response to hydroxyurea. Genetic modulation of sickle cell disease: Homozygosity for a single Î²-globin gene mutation (HBB; glu6val) causes sickle cell anemia.
Spiral Galaxies. Spiral galaxy M100. Spiral galaxies have three main components: a bulge, disk, and halo (see right). The bulge is a spherical structure found in the center of the galaxy. This feature mostly contains older stars. The disk is made up of dust, gas, and younger stars. The disk forms arm structures.
Studies of the rotation of the Milky Way show that the halo dominates the mass of the galaxy, but the material is not visible, now called dark matter. The Disk The disk of the Galaxy is a flattened, rotating system which contains the Sun and other intermediate-to-young stars. The sun sits about 2/3 of the way from the center to the edge of the disk (about 25,000l.y. by the most modern estimates).