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Trypophobia Definition. There are thousands of people who claim they have the Trypophobia (fear of holes in the skin). However, It is not recognized in the American Psychiatric Associationâs Diagnostic and Statistical Manual of Mental Disorders (DSM) or other scientific literature.
Photos: Trypophobia: A fear of holes Others believe that it could be a built-in reaction to mold, parasites and contagious diseases. For example, mold on bread or vegetables have certain visual cues and characteristics that are similar to trypophobic stimuli,  said researcher An Lee.