Van Pelt in Jumanji: The Animated Series. Van Pelt returns as a recurring villain in the animated series based on the movie. He is revealed to be a part of the game, and when he actually dies in an episode, Peter starts to become him little by little, but is saved by Alan and Judy.
http://www.chacha.com/question/which-episode-of-grey's-anatomy-does-izzy-get-diagnosed-with-cancer. Izzie discovers she has metastatic melanoma (Stage IV) in season 5 episode 17 I Will Follow You Into the Dark of Grey's Anatomy.
The cancer then spread to Marley's brain, lungs, liver, and stomach. After playing two shows at Madison Square Garden as part of his fall 1980 Uprising Tour, he collapsed while jogging in NYC's Central Park. The remainder of the tour was subsequently cancelled.