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It is named after John Langdon Down, the British doctor who fully described the syndrome in 1866. Some aspects of the condition were described earlier by Jean-Ãtienne Dominique Esquirol in 1838 and Ãdouard SÃ©guin in 1844. In 1957, the genetic cause of Down syndrome, an extra copy of chromosome 21, was discovered.
The Strait of Juan de Fuca explored by John Meares On Sunday, June 29, 1788, Captain John Meares sighted an inlet that he named the Strait of Juan de Fuca. Meares was most likely the first European explorer to reach the Strait since Juan de Fuca's claim to have been there in 1592 was never documented.