In sickle cell disease, red blood cells are produced but then become deformed into the sickle shape, which causes red blood cells to lose their oxygen carrying capacity. The body subsequently becomes dehydrated, or with a fever.
some bipolar depression symptoms are the same as major depression symptoms persistent sadness feelings of hopelessness worthlessness and helplessness loss of interest in activities or hobbies once pleasurable including sex
Signs and symptoms of bipolar disorder. Bipolar disorder can look very different in different people. The symptoms vary widely in their pattern, severity, and frequency. Some people are more prone to either mania or depression, while others alternate equally between the two types of episodes.