Thursday, January 24, 2013. Saltillo Violence: Mother Killed With Daughter, Baby Found With Bodies, 3 Sicarios Killed. in Coahuila, from Torreon (la Laguna) east to Saltillo, north to Piedras and AcuÃ±a, the once relatively peaceful state seems to have become the stage of violence and crime. Above is Perla she is the mother of the baby.
Splice site mutation. A splice site mutation is a genetic mutation that inserts, deletes or changes a number of nucleotides in the specific site at which splicing takes place during the processing of precursor messenger RNA into mature messenger RNA.
Splicing of mRNA is performed by an RNA and protein complex known as the spliceosome, containing snRNPs designated U1, U2, U4, U5, and U6 (U3 is not involved in mRNA splicing). U1 binds to the 5' GU and U2, with the assistance of the U2AF protein factors, binds to the branchpoint A within the branch site.he Sxl protein is a splicing repressor that binds to an ISS in the RNA of the Tra transcript near the upstream acceptor site, preventing U2AF protein from binding to the polypyrimidine tract. This prevents the use of this junction, shifting the spliceosome binding to the downstream acceptor site.