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Carboxylic derivatives are described as compounds that can be converted to carboxylic acids via simple acidic or. basic hydrolysis. The most important acid derivatives are esters, amides and nitriles, although acid halides and anhydrides are also. derivatives (really activated forms of a carboxylic acid).
As amino acids have both a primary amine group and a primary carboxyl group, these chemicals can undergo most of the reactions associated with these functional groups. These include nucleophilic addition, amide bond formation, and imine formation for the amine group, and esterification, amide bond formation, and decarboxylation for the carboxylic acid group.