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High HDL. High levels of good, or HDL, cholesterol can significantly decrease a person's risk for heart disease. According to the latest guidelines, a level of 60 mg/dL and above is considered high.. In most cases, the cause is unknown, but it does seem to run in families. High HDL levels can also be caused by certain cholesterol medications, aerobic exercise, and regular alcohol consumption.
People who have high blood cholesterol have a greater chance of getting coronary heart disease, also called coronary artery disease. (In this article, the term âheart diseaseâ refers to coronary heart disease.). The higher the level of LDL cholesterol in your blood, the GREATER your chance is of getting heart disease. high LDL level leads to a buildup of cholesterol in your arteries. (Arteries are blood vessels that carry blood from your heart to your body.). HDL cholesterol sometimes is called âgoodâ cholesterol.