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Melanosis coli is a condition usually associated with chronic laxative use in which dark pigment is deposited in the lamina propria (one of the lining layers) of the large intestine (colon). The pigment deposition results in a characteristic dark brown to black discoloration of the lining of the large intestine.
The lining has changed from a light pink to a dark brown or black and is seen during the colonoscopy test. The change in color is due to deposits of dark pigment in the lining of the colon. The change in color may be slight or very distinct. Melanosis coli is usually caused by long term laxative use.Stopping the use of certain laxatives may lessen the change in color over time. Do not use laxatives with Senna or Cascara in them. In some severe cases melanosis coli may slow down your bowel function.he lining has changed from a light pink to a dark brown or black and is seen during the colonoscopy test. The change in color is due to deposits of dark pigment in the lining of the colon. The change in color may be slight or very distinct. Melanosis coli is usually caused by long term laxative use.