1 Examples are morphine and heroin. 2  Worldwide, an estimated 69 000 people die from opioid overdose each year.  There are an estimated 15 million people who suffer from opioid dependence (i.e. an addiction to opioids).
Berberine is a natural alkaloid found in a wide variety of traditional herbs including goldenseal, barberry and Oregon grape. Many herbalists credit this unique alkaloid for the benefits of ancient herbal tonics used by native populations throughout the world.
Berbere (Amharic: á á­á á¬ berberÄ, Tigrinya: á á­á á¨ berbere) is a spice mixture whose constituent elements usually include chili peppers, garlic, ginger, basil, korarima, rue, ajwain or radhuni, nigella, and fenugreek.erbere sometimes encompasses herbs and spices that are less well known internationally. The latter include both cultivated plants and those that grow wild in Ethiopia, such as korarima (Aframomum corrorima) and long pepper.