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Fabrication is the practice of inventing data or results and recording and/or reporting them in the research record. Both of these schemes are probably among the most serious offenses in scientific research as they challenge the credibility of everyone and everything involved in a research effort.
A fabrication is something made up, like a lie. Telling your boss that the subway broke down when in fact you just forgot to set your alarm is a fabrication. The word fabrication was originally used to talk about manufacturing or construction, and it referred to the act of assembling something. Tires and steering wheels are necessary materials for automobile fabrication.