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Yes. In relation to Theodore, Franklin Roosevelt was a distant cousin who later become a nephew-in-law, when he married Teddy's niece, Anna Eleanor Roosevelt. Franklin and Theodore Roosevelt were both descendants from Dutch colonists, who settled in the New York area in the mid-17th century. According to any Franklin Roosevelt biography, the two were fifth cousins, having a paternal relative in common (Nicholas Roosevelt, 1658-1742).
James Roosevelt met his wife at a Roosevelt family gathering in the home of Theodore's mother, and James' son Franklin married Theodore's niece Eleanor. The Roosevelt Family is generally associated with the state of New York. Harvard University educations have been common among many members of the Roosevelt Family.