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Mitochondrial DNA and Diseases. Abstract. The mitochondrial genome (mtDNA, mitochondrial deoxyribonucleic acid) is an essential source of extranuclear DNA in mammalian cells, located in the matrix of the organelle.
Plants and Animals. In plants and animals DNA is also found in the cell nucleus. The DNA of all animals is very similar. The major differences are in the number of chromosomes and genes, and the arrangement of base pairs within these genes.