Tweet. There are no known adverse reactions between Plavix (Clopidogrel) and eating grapefruit, or drinking grapefruit juice. Furthermore, there is no sufficient evidence that illustrates grapefruit juice, or the fruit itself would interfere with the effectiveness of Plavix.
Other, more minor side effects include constipation, headache, dry mouth and insomnia (because the chemicals in these drugs also influence sleep patterns). Herbal diet pills, even though they're all natural, can have potentially dangerous side effects depending upon their ingredients.
Other antidepressants, like fluoxetine, sertraline and venlafaxine also may lead to weight gain, especially if used long term. Short-term use of most SSRIs and SNRIs is not associated with weight gain, Eisensen says, but if people are on them a year or longer, they can gain a few pounds or more..