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Definition: Disorders caused by abnormal or absent immunologic mechanisms, whether humoral, cell-mediated, or both. Synonym(s): Immune Disorders / Immunologic Diseases / Diseases of Immune System / Immune Diseases /.
In autoimmune diseases, such as multiple sclerosis (MS), type 1 diabetes, Graves' disease and systemic lupus erythematosus (SLE), the immune system is unable to distinguish between healthy tissues and harmful antigens. The result is destruction of tissue, abnormal growth, or changes in organ function.ith antigen-specific immunotherapy, scientists were able to selectively target the cells that cause autoimmunity and reverse their role. The aggressive cells were converted to cells capable of protecting against disease. This method of converting cells has been used earlier in allergy treatment.