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Lymph is present throughout the body, and circulates through lymphatic vessels. These drain into and from lymph nodes â afferent vessels drain into nodes, and efferent vessels from nodes. When lymph fluid enters a node, it drains into the node just beneath the capsule in a space called the subcapsular sinus. The subcapsular sinus drains into trabecular sinuses and finally into medullary sinuses.
In this article, we discuss and illustrate the use of lymphoscintigraphy in the detection of lymphatic drainage patterns and localization of the sentinel nodes (ie, the first draining lymph nodes in each draining lymphatic basin) in patients with intermediate thickness malignant melanomatous lesions.