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Catalog No.S4186. Domiphen bromide is a quaternary ammonium antiseptic with actions as a cationic surfactant.In vitro. Recombinant 4-diphosphocytidyl-2-C-methyl-d-erythritol synthase (IspD) is sensitive to Domiphen Bromide (DMB), as observed through an IspD activity assay.The inhibitory effect of DMB on IspD is confirmed by both the newly-established high-throughput screening system and traditional enzyme kinetic assays.omiphen bromide is a quaternary ammonium antiseptic with actions as a cationic surfactant. In vitro. Recombinant 4-diphosphocytidyl-2-C-methyl-d-erythritol synthase (IspD) is sensitive to Domiphen Bromide (DMB), as observed through an IspD activity assay.
Key points from the evidence. Aclidinium bromide (Eklira Genuair) is an inhaled long-acting muscarinic antagonist (LAMA) for maintenance bronchodilator treatment to relieve symptoms in adults with chronic obstructive pulmonary disease (COPD).It received a European marketing authorisation in July 2012 and was launched in the UK in September 2012.2012) Efficacy and safety of a 12-week treatment with twice-daily aclidinium bromide in COPD patients (ACCORD COPD I). COPD: Journal of Chronic Obstructive Pulmonary Disease 9: 90â101. Jones PW, Singh D, Bateman ED et al.