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Irritant contact dermatitis. Irritant contact dermatitis occurs when your skin comes into direct contact with a substance that damages the outer layer of your skin, causing redness, itching, and a burning or stinging sensation.
One of the most common side effects is a skin condition called radiation dermatitis, which can range from a mild, red rash (erythema) and itchy, peeling or flaking skin (dry desquamation) to a more severe reaction with blisters and wet, peeling skin (moist desquamation).