Members of the DEWS Definition and Classification. Subcommittee developed a contemporary definition of dry eye disease and a three-. part classification system based on etiology, causative mechanisms and disease. severity.
Metaplasia. Definition: Metaplasia is the reversible replacement of one differentiated cell type with another differentiated cell type. Metaplasia causes precursor cells to change their cell fate, and do not change existing differentiated cells.he most common epithelial metaplasia is columnar to squamous (squamous metaplasia), as occurs in the respiratory tract in response to chronic irritation.
(April 2014). Metaplasia (Greek : change in form) is the reversible replacement of one differentiated cell type with another mature differentiated cell type.The change from one type of cell to another may generally be a part of normal maturation process or caused by some sort of abnormal stimulus.ormal physiological metaplasia-such as that of the endocervix is highly desirable. The medical significance of metaplasia is that in some sites where pathological irritation is present cells may progress from metaplasia, to develop dysplasia, and then malignant neoplasia (cancer).