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Because anencephaly is caused by abnormalities of the neural tube, it is classified as a neural tube defect. Because the neural tube fails to close properly, the developing brain and spinal cord are exposed to the amniotic fluid that surrounds the fetus in the womb.
A Honor Society of Nursing (STTI) answered. In the United States, neural tube defects occur in about one out of every 1,000 pregnancies. That means a baby in the United States has about a one tenth of 1 percent chance of being born with a neural tube defect.