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Q: How often do doctors give cortisone injections to a patient? A: We try to limit the injection to one every three months for any single joint, but also we like to limit it to a total of six injections a year for the whole body. We know that the cortisone can sometimes weaken or suppress the immune system and, in diabetics, it raises blood sugar.
Since the relief is just temporary patients should be even more cautious with their knee so as to not injure it further. Long term and repeated use of cortisone will cause bone loss, weakening of tendons, and cartilage loss in the knee joint. This is why doctors only allow a maximum of three injections per year.