Definition of sociopolitical. : of, relating to, or involving a combination of social and political factors.
Beta-1 receptors are found in the heart, and when stimulated will increase herat rate and cardiac contractility. Beta-2 receptors are found on vascular smooth muscle located in the heart and skeletal muscle, and when they are activated, they dilate and decrease SVR.
Like other metabotropic glutamate receptors, mGluR1 is a ligand-operated channel that, upon binding of L-glutamate, undergoes a conformational change leading to activation of its associated G protein, which in turn controls various second messenger systems.