The leading modifiable risk factors worldwide are: 1  tobacco smoking, which is strongly associated with lung cancer, mouth, and throat cancer; 2  drinking alcohol, which is associated with a small increase in oral, esophageal, breast, liver and other cancers; 3  a diet low in fruit and vegetables,
Trier Tourism: Best of Trier. Trier, Germany. Trier, which lies in the Moselle wine region along the banks of the Moselle River, is the oldest city in Germany. The city is home to the University of Trier.
Rhineland, German Rheinland, French RhÃ©nanie, historically controversial area of western Europe lying in western Germany along both banks of the middle Rhine River. It lies east of Germanyâs border with France, Luxembourg, Belgium, and the Netherlands.