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Born Alessandro di Mariano Filipepi in Florence in 1445, Botticelli was apprenticed to a goldsmith. Later he was a pupil of the painter Fra Filippo Lippi. He spent all his life in Florence except for a visit to Rome in 1481-82. There he painted wall frescoes in the Sistine Chapel of the Vatican. In Florence, Botticelli was a protege of several members of the powerful Medici family.
Sandro Botticelli's painting of the Adoration of the Magi has an inserted self-portrait at the far right: the position in the corner and the gaze out to the viewer are very typical of such self-portraits.