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Tobacco would be the salvation not only of Jamestown but of the  state of Virginia. Tobacco remain a profitable case crop in the  region until the negative campaign against â¦the tobacco industry  decreased the demand.
Because Jamestown was built on traditional hunting grounds of the Algonkin Indians, trouble arose soon after their arrival. By the winter of 1607, only 38 out of the original 104 settlers were still alive. Food shortages were making unbearable situations even worse. Jamestown was on the brink of collapse until JOHN SMITH formulated plans to procure Indian corn and other foods via trade.