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According to experts, it takes 15- 20 min for Ibuprofen to kick in and close to 2 hours to take effect. It also depends on the form of Ibuprofen, like; if you are taking ibuprofen in liquid form it will take lesser time as the body doesnât need to break down the capsule/Tablet. It quickly goes to the bloodstream and relieves the pain. If you are taking it tablet form it might take more time.
Best Answer: Ibuprofen and aleve are both anti inflammatory medicine...very similar. It would be the same as taking the next dose of ibuprofen.I think that is six hours, but you would be safe to take some tylenol in four hours.If it is for a headache I use Excedrin extra strength. It seems to work wonders on my headaches.