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The normal lipase level is 12-70 U/L. Normal values may vary from laboratory to laboratory. Causes of hyperlipasemia (high lipase levels) may include: Pancreatitis - also known as inflammation of the pancreas, can cause amylase and lipase levels to be increased up to 3 times normal. Both values should be increased, in order to carry the diagnosis of pancreatitis.
A high lipase level in the blood may indicate the presence of a condition affecting the pancreas. In acute pancreatitis, lipase levels are frequently very high, often 5 to 10 times higher than the highest reference value (often called the upper limit of normal). low level of lipase in the blood may indicate permanent damage to the lipase-producing cells in the pancreas. This can occur in chronic diseases that affect the pancreas such as cystic fibrosis.