Do not take more than your recommended dose. An Advil overdose can damage your stomach or intestines. The maximum amount of ibuprofen for adults is 800 milligrams per dose or 3200 mg per day (4 maximum doses). Use only the smallest amount of ibuprofen needed to get relief from your pain, swelling, or fever. A child's dose of ibuprofen is based on the age and weight of the child.
High doses of common pain drugs NSAIDs can cause heart attack: study. NSAIDs increase blood pressure and likelihood of clotting, which can wreak havoc for your heart, the authors of a new study note. High doses of some commonly used pain drugs like ibuprofen can increase heart attacks, strokes and related deaths by about a third, a study warned on Thursday. The drugs, known as non-steroidal anti-inflammatory drugs (NSAIDs), are widely used to manage pain caused by inflammatory disorders.
Illegal Drugs. Most street drugs, including heroin, cocaine and ecstasy can cause high blood pressure, stroke, heart failure and even death, in some cases from only one use. Cocaine, heroin and amphetamines also can cause kidney damage.