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Glycolysis is a series of reactions that and extract energy from glucose by splitting it into two three-carbon molecules called pyruvates. Glycolysis is an ancient metabolic pathway, meaning that it evolved long ago, and it is found in the great majority of organisms alive today2,3^{2,3}â2,3ââstart superscript, 2, comma, 3, end superscript. In organisms that perform cellular respiration, glycolysis is the first stage of this process. However, glycolysis doesnât require oxygen, and many anaerobic organismsâorganisms that do not use oxygenâalso have this pathway.
Glycolysis is an oxygen independent metabolic pathway, meaning that it does not use molecular oxygen (i.e. atmospheric oxygen) for any of its reactions. However the products of glycolysis (pyruvate and NADH + H +) are sometimes disposed of using atmospheric oxygen.