1 To establish the maximum tolerable dose of betahistine dihydrochloride (betahistine) within the range of 50 mg to 300 mg/day that appears to be effective for atypical depression. Are at significant risk of suicide as indicated by a score of 3 or greater on item number 11 on the HAM-D 28. 2  Have received any investigational product within 28 days of Screening. 3  Have used any antidepressant within 7 days of Screening (14 days for MAOIs; 21 days for fluoxetine).
Boulder Creek, California. Boulder Creek is a census-designated place (CDP) in Santa Cruz County, California, with a population of 4,923 as of the 2010 census.
The Boulder Creek, CA air quality index is a median value which considers the most hazardous air pollutants. The Boulder Creek, CA air quality index is 34.8% less than the California average and 27.6% less than the national average. The Boulder Creek, CA pollution index is the sum of the most hazardous air pollutants displayed in pounds. The Boulder Creek, CA pollution index is 70.1% less than the California average and 7% greater than the national average.