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Still, even if a woman tests negative, her baby will still be given a hepatitis B shot at birth in the hospital newborn nursery (unless you firmly request otherwise) as a 'catch all' of sorts. Newborns of HBsAg negative mothers should begin the hepatitis B vaccine series before hospital discharge.
When did vaccine first become available for diphthe-ria, tetanus, and pertussis? The first inactivated toxin, or toxoid, against diph-theria was developed around 1921, but it was not widely used until the 1930s.