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Another option is to mix small amounts of apple cider vinegar with the animal's drinking water; consuming this solution is known to change the blood pH of the horse, thus keeping horseflies away. Cider vinegar, coupled with essential oils, is also used in home sprays as the sharp odor may repeal horseflies.
Spray the horse. Spray the pyrethrin mixture all over the horse's body, being careful to avoid the eyes, ears, and nose. 1  Although lice are found primarily in horses' manes, tails, fetlocks and along their backs, the lice may also be hiding anywhere within the coat.