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Brinzolamide is a carbonic anhydrase inhibitor which has been found to be effective in lowering the elevated intraocular pressure associated with ocular hypertension and glaucoma. The distribution coefficient, IC50 and Ki values for brinzolamide are 6.56, 3.19 nM and 0.13 nM respectively.
For the treatment and management of all of these types of glaucoma, medical marijuana can be effective. Medical marijuana's primary benefit for glaucoma patients is its effect on intraocular pressure (IOP). In one study, more than 80% of patients who smoked marijuana using an ice-cooled water pipe experienced a reduction in IOP of 16-45%.