Clostridium difficile colitis or pseudomembranous colitis is colitis (inflammation of the large intestine) resulting from infection with Clostridium difficile, a spore-forming bacterium. It causes an infectious diarrhea called C. difficile associated diarrhea (CDAD).Latent symptoms of Clostridium difficile infection (CDI) often mimic some flu-like symptoms and may mimic disease flare-ups in people with inflammatory bowel disease âassociated colitis.C. difficile releases toxins that may cause bloating and diarrhea, with abdominal pain, which may become severe.atent symptoms of Clostridium difficile infection (CDI) often mimic some flu-like symptoms and may mimic disease flare-ups in people with inflammatory bowel disease âassociated colitis. C. difficile releases toxins that may cause bloating and diarrhea, with abdominal pain, which may become severe.
The initiation of DNA replication occurs in two steps. First, a so-called initiator protein unwinds a short stretch of the DNA double helix. Then, a protein known as helicase attaches to and breaks apart the hydrogen bonds between the bases on the DNA strands, thereby pulling apart the two strands.
Transcription is the first of overall two protein synthesis steps. During transcription, the information encoded in the DNA is copied to a RNA molecule as one strand of the DNA double helix is used as a template. The RNA molecule is sent to the cytoplasm, which helps to bring all components required for the actual protein synthesis together â amino acids, transport RNAs, ribosomes, etc.