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Brinzolamide is a carbonic anhydrase inhibitor which has been found to be effective in lowering the elevated intraocular pressure associated with ocular hypertension and glaucoma. The distribution coefficient, IC50 and Ki values for brinzolamide are 6.56, 3.19 nM and 0.13 nM respectively.
Furthermore, methylcobalamin is the only form of B12 that is used by the body in the nervous system. That makes it of great interest to anyone concerned about glaucoma. For those reasons I would not dismiss methylcobalamin in favor of dibencozide. The glaucoma-specific research I've seen uses methylcobalamin.