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Causes of Charcot foot. Causes of Charcot foot result from peripheral neuropathy, meaning the neuropathy is a result of another condition â like diabetes or leprosy. The bones weaken over time, increasing the risk of fractures and changing the physical shape of the foot.
Clinical findings in patients with an acute Charcot process include warmth, erythema and swelling 2 â 6 (Figures 1a and Figures 1b) . Pain and tenderness are usually absent because of sensory neuropathy, which is universal and is probably a component of the basic pathogenesis of the Charcot foot.