Marfan syndrome (also called Marfan's syndrome) is a genetic disorder of connective tissue. It has a variable clinical presentation, ranging from mild to severe systemic disease. The most serious manifestations involve defects of the heart valves and aorta, which may lead to early death if not properly managed.
noun. 1  a big deal. 2  See more words with the same meaning: exclamations (list of) . 3  See more words with the same meaning: unimportant, useless.
Slang terms with the same meaning. Other terms relating to 'uncool person, jerk, asshole (general insults - list of)': Definitions include: An acronym has been invented for the term, but long after the term entered use: Beautiful Intellectuals That Cause Hard-ons.. Definitions include: head or haircut.