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Brinzolamide is a carbonic anhydrase inhibitor which has been found to be effective in lowering the elevated intraocular pressure associated with ocular hypertension and glaucoma. The distribution coefficient, IC50 and Ki values for brinzolamide are 6.56, 3.19 nM and 0.13 nM respectively.
Various glaucoma eye drops are classified by the active ingredient chemical that helps make the drug work. Beta-blockers. Used in a variety of glaucoma eye drops, beta-blockers were at one time the drugs of first choice in treating glaucoma. These drugs work by decreasing fluid (aqueous) production in the eye and now are often prescribed as an adjunct to or in combination with prostaglandins.