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Brinzolamide is a carbonic anhydrase inhibitor which has been found to be effective in lowering the elevated intraocular pressure associated with ocular hypertension and glaucoma. The distribution coefficient, IC50 and Ki values for brinzolamide are 6.56, 3.19 nM and 0.13 nM respectively.
BRAND NAME: Alphagan P. DRUG CLASS AND MECHANISM: Brimonidine is is an ophthalmic solution used for the treatment of one type of glaucoma, open-angle glaucoma. In this type of glaucoma, too much fluid (aqueous humor) is made within the eye and causes high pressures within the eye.