When a reaction occurs at the site of a vesicant injection (e.g., in patients receiving cancer chemotherapy), close monitoring by a physician or the injection of local antidotes may be required. Reactions that result in infection or necrosis may need to be treated with antibiotics or with surgical dÃ©bridement.
Cream that contains cortisone might help with inflammation. Cortisone cream can be used to treat poison ivy rashes. Cortisone is the primary ingredient in over-the-counter hemorrhoid creams. Cortisone cream can be used to provide relief from itchy hives.
A cortisone injection can also be used to give short-term pain relief and reduce the swelling from inflammation of a joint, tendon, or bursa in, for example, the joints of the knee, elbow, and shoulder and into a broken coccyx.n the peripheral tissues, cortisol is converted to cortisone by the enzyme 11-beta-steroid dehydrogenase. Cortisol has much greater glucocorticoid activity than cortisone, and, thus, cortisone can be considered an inactive metabolite of cortisol.