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What are quinolones? Quinolones are antimicrobial agents effective in the treatment of selected community-acquired and nosocomial infections. They are usually administered orally, but some can be given intravenously for treatment of serious infections. Quinolones are bactericidal and exhibit concentration-dependent killing.
Quinolone antibiotics (including ofloxacin) may cause serious and possibly permanent tendon damage (such as tendonitis, tendon rupture), nerve problems in the arms and legs (peripheral neuropathy), and nervous system problems.