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dobutamine hydrochloride. A synthetic beta-agonist whose primary effect is to increase cardiac contractility, with little effect on systemic vascular resistance. It produces less tachycardia than dopamine and has no effect on renal blood flow. It is of use in congestive heart failure and cardiogenic shock.
Medical Definition of DOBUTAMINE. : a strongly inotropic catecholamine administered intravenously in the form of its hydrochloride C18H23NO3Â·HCl especially to increase cardiac output and lower wedge pressure in heart failure and after cardiopulmonary bypass surgery.edical Definition of DOBUTAMINE. : a strongly inotropic catecholamine administered intravenously in the form of its hydrochloride C18H23NO3Â·HCl especially to increase cardiac output and lower wedge pressure in heart failure and after cardiopulmonary bypass surgery.