Evidence for the use of low frequency ultrasound to treat wounds is limited and consists of studies that lack adequate. sample sizes and proper control groups. Additional research with larger trials is needed to demonstrate that low. frequency ultrasound is beneficial for health outcomes in patients with wounds.
The neurotransmitter, acetylcholine, once it has diffused into the synapse, binds to the nicotinic acetylcholine receptors, which are found in the motor end plate. These receptors are ligand-gated ion channels, and once acetylcholine has binded to the receptors, it causes the channels to open.
Now that we have described the structure of the neuromuscular junction, we are ready to examine what happens there. When the nerve impulse reaches the axon terminals, a chemical referred to as a neurotransmitter is released. The specific neurotransmitter that stimulates skeletal muscle cells is acetylcholine, or Ach. Acetylcholine diffuses across the synaptic cleft and attaches to receptors (membrane proteins) that are part of the sarcolemma. If enough acetylcholine is released, the sarcolemma at that point becomes temporarily more permeable to sodium ions (Na+), which rush into the muscle cell and to potassium ions (K +) which