Tell your doctor if any of the following side effects become severe or don't go away: 1  Mild itching, burning, stinging, or tingling skin. 2  Redness or soreness. 3  Increased sensitivity to hot or cold temperatures. 4  Acne. 5  Muscle or back pain. 6  Headache. 7  Flu-like symptoms. 8  Runny or stuffy nose. 9  Nausea.
The Krebs cycle, which is also known as the citric acid cycle or tricarboxylic acid cycle, is part of a series of chemical reactions that organisms use to break food down into a form of energy that cells can use.
The cycle consumes acetate (in the form of acetyl-CoA) and water, reduces NAD+ to NADH, and produces carbon dioxide as a waste byproduct. The NADH generated by the citric acid cycle is fed into the oxidative phosphorylation (electron transport) pathway. The net result of these two closely linked pathways is the oxidation of nutrients to produce usable chemical energy in the form of ATP. In eukaryotic cells, the citric acid cycle occurs in the matrix of the mitochondrion. In prokaryotic cells, such as bacteria which lack mitochondria, the citric acid cycle reaction sequence is performed in the cytosol with the proton gradient for ATP production being across the cell's surface (plasma membrane) rather than the inner membrane of the mitochondrion