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Brinzolamide is a carbonic anhydrase inhibitor which has been found to be effective in lowering the elevated intraocular pressure associated with ocular hypertension and glaucoma. The distribution coefficient, IC50 and Ki values for brinzolamide are 6.56, 3.19 nM and 0.13 nM respectively.
Acetazolamide is a medicine used to treat glaucoma. Glaucoma is increased pressure in the eye. Acetazolamide reduces this pressure. This medicine may also be used to treat seizures. It reduces the number of seizures. You may hear acetazolamide called by its brand name, Diamox.