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Causes of Cross-eyed. Some of the causes of Cross-eyed are included in the list below: 1  Weak eye muscles. 2  Eye muscle paralysis (see Paralysis symptoms). 3  Eye muscle disease. 4  Eye muscle nerve disorders. 5  Eye vision disorder-especially if the eyes are affected differently.
Commonly referred to as crossed eyes, esotropia is a common type of strabismus in which one or both eyes turn inward toward the nose. It is most often identified in children between the ages of 2 and 4, although it can occur at any age.