Widespread, or generalized, itching from liver disease can appear before other signs or symptoms of cholestasis develop. Itching is typically most severe on the palms and soles of the feet, and worse in the late evening and night. No rash or other lesions are present, except when the act of scratching itself damages the skin.
Barinholtz is married to Erica Hanson, with whom he has a daughter. He spent two years in Amsterdam with the famed comedy troupe Boom Chicago, along with Jordan Peele, Josh Meyers and Nicole Parker.
Rock 'n' roll pioneer Ike Turner, former husband of singer Tina Turner, attends ceremonies unveiling director John Singleton's star on the Hollywood Walk of Fame in Hollywood in this August 26, 2003 file photo.