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Summary. 1  Ambien and Lunesta are both prescription drugs intended for the treatment of insomnia. 2  Both can be availed of in tablet form. 3  Ambien and Lunesta have an immediate sedative effect that last 7-8 hours per dosage.  Ambienâs efficacy last up to 35 days, while Lunesta remains effective up to 6 months.
Lunesta is a sleep medicine that is commonly prescribed for the treatment of insomnia in adults. The medication is available in three different strengths. While Lunesta has proven to be effective in helping people fall asleep faster and stay asleep longer, it should be taken with caution because it is a controlled substance that can be abused.