Social exclusion (or marginalization) is social disadvantage and relegation to the fringe of society.It is a term used widely in Europe, and was first used in France. It is used across disciplines including education, sociology, psychology, politics and economics.ocial exclusion (or marginalization) is social disadvantage and relegation to the fringe of society.
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is thought to be caused by trauma to dentoalveolar structures that have a limited capacity for bone healing due to the effects of bisphosphonate therapy. See the image below. Exposed, necrotic bone in the left anterior maxilla.
Fast Facts. 1  Osteonecrosis of the jaw (ONJ) may occur in patients taking strong antiresorptive medications such as bisphosphonates or RANKL inhibitors.  Most patients with ONJ who are taking antiresorptive therapy for osteoporosis can be healed with conservative treatment and often do not require surgery.