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In 1881, Carl Wernicke first described an illness that consisted of paralysis of eye movements, ataxia, and mental confusion, in 3 patients. The patients, 2 males with alcoholism and a female with persistent vomiting following sulfuric acid ingestion, exhibited these findings, developed coma, and eventually died.
When this area of the brain is damaged, a disorder known as Wernicke's aphasia can result. 1  This invovles being able to speak in phrases that sound fluent yet lack meaning. 2  When Leborgne died, Broca conducted a postmortem exam on the man's brain and found a lesion in an area of the frontal lobe.