Widespread, or generalized, itching from liver disease can appear before other signs or symptoms of cholestasis develop. Itching is typically most severe on the palms and soles of the feet, and worse in the late evening and night. No rash or other lesions are present, except when the act of scratching itself damages the skin.
Barinholtz is married to Erica Hanson, with whom he has a daughter. He spent two years in Amsterdam with the famed comedy troupe Boom Chicago, along with Jordan Peele, Josh Meyers and Nicole Parker.
He had six children: sons Ike Jr. and Michael (with Lorraine Taylor), Ronald/Ronnie (with Tina Turner), and daughter Mia (with Margaret Ann Thomas). Mia Turner was conceived and born during Ike's marriage to Tina in the late 1960s.