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Causes of Cross-eyed. Some of the causes of Cross-eyed are included in the list below: 1  Weak eye muscles. 2  Eye muscle paralysis (see Paralysis symptoms). 3  Eye muscle disease. 4  Eye muscle nerve disorders. 5  Eye vision disorder-especially if the eyes are affected differently.
An irregularity in the curvature of the cornea or lens can cause the impaired vision of astigmatism. strabismus (or squint or crossed eyes) is usually caused by weakness in muscles that control movement of the eyeball.