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Nootropics ( /noÊ.ÉËtrÉpáµ»ks/ noh-É-TROP-iks)âalso called smart drugs or cognitive enhancersâare drugs, supplements, or other substances that improve cognitive function, particularly executive functions, memory, creativity, or motivation, in healthy individuals.[1][2] The use of cognition-enhancing drugs by healthy individuals in the absence of a ...