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Brinzolamide is a carbonic anhydrase inhibitor which has been found to be effective in lowering the elevated intraocular pressure associated with ocular hypertension and glaucoma. The distribution coefficient, IC50 and Ki values for brinzolamide are 6.56, 3.19 nM and 0.13 nM respectively.
These glaucoma drugs also reduce the production of aqueous humor. Examples of such glaucoma drugs include Dorzolamide (Brand name: Trusopt) and Brinzolamide (Brand name: Azopt). Some of the side-effects of these glaucoma drugs include frequent urination and a tingling sensation in the fingers and toes.