âº They act as a framework along which motor proteins can move structures in the cell. Microtubules are assembled from molecules of the protein tubulin. Tubulin is a dimerâa molecule made up of two monomers. The polypeptide monomers that make up this protein are known as a-tubulin and b-tubulin.
Prior to initiation of cefuroxime therapy, careful inquiry should be made concerning previous hypersensitivity reactions to cephalosporins, penicillins, or other drugs. Cefuroxime axetil /is/ contraindicated in patients who are hypersensitive to cefuroxime or other cephalosporins and should be used with caution in patients with a history of hypersensitivity to penicillins.
Clinical Case for Discussion: You are attending to a healthy 72-year-old female for open reduction and internal fixation of a hip fracture. She is allergic to penicillin â she developed hives from a dose when she was a child. The orthopedic surgeon orders 1 gram of cefazolin IV before incision.