A collection of particular persons or items, formed into one body; as a corporation aggregate, which is one formed of a number of natural persons; the union of individual charges make an aggregate charge.
Pleiotropy describes the genetic effect of a single gene on multiple phenotypic traits. The underlying mechanism is that the gene codes for a product that is, for example, used by various cells, or has a signaling function on various targets.A classic example of pleiotropy is the human disease phenylketonuria (PKU).nsourced material may be challenged and removed. (September 2013). Pleiotropy occurs when one gene influences two or more seemingly unrelated phenotypic traits, an example being phenylketonuria, which is a human disease that affects multiple systems but is caused by one gene defect.
Citation: Lobo, I. (2008) Pleiotropy: One Gene Can Affect Multiple Traits. Nature Education 1(1):10. How can a mutation in one single gene cause a disease with a wide range of symptoms? This situation is referred to as pleiotropy, and it has been identified in a wide range of species, even humans.