A sprain is an injury to a ligament. Ligaments are the connective tissues that connect bones to bones across a joint. The most common thumb sprain involves the collateral ligaments of the Metacarpophalangeal (MCP) joint. These types of injuries are common in sports and falls on to an outstretched hand.
Nicotinamide is a water-soluble component of the vitamin B complex group. In vivo, Nicotinamide is incorporated into nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP). NAD and NADP function as coenzymes in a wide variety of enzymatic oxidation-reduction reactions essential for tissue respiration, lipid metabolism, and glycogenolysis.
Those who took nicotinamide had 1.77 non-melanoma skin cancers. Thatâs a 23% reduction in risk with a p value of 0.02. There was a comparable effect on basal cell skin cancer and squamous cell skin cancer. Unlike niacin, another form of B3, the supplement did not cause headaches, flushing, or low blood pressure.