Social exclusion (or marginalization) is social disadvantage and relegation to the fringe of society.It is a term used widely in Europe, and was first used in France. It is used across disciplines including education, sociology, psychology, politics and economics.ocial exclusion (or marginalization) is social disadvantage and relegation to the fringe of society.
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is thought to be caused by trauma to dentoalveolar structures that have a limited capacity for bone healing due to the effects of bisphosphonate therapy. See the image below. Exposed, necrotic bone in the left anterior maxilla.
Additional approved indications for bisphosphonates currently include other forms of osteoporosis (such as that which occurs in men or is associated with glucocorticoid therapy), Paget disease of bone, hypercalcemia of malignancy, and metastatic bone disease.