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When you crack your knuckles, you're actually doing more bursting than cracking. The popping noise you hear is caused by small bubbles bursting in your synovial fluid, a yolk-like substance that lubricates the areas between bones and reduces friction for ease of movement.
In orthopedic medicine and sports medicine, crepitus describes a popping, clicking or crackling sound in a joint. Joint popping sounds may mean that air is moving in the joint, which is usually harmless. People most often notice crepitus in their knees, but it can also happen in other joints like the shoulder, elbow or neck. Crepitus with pain can be a sign of wear and tear or injury. If crepitus is painful, you should consult a doctor.