A collection of particular persons or items, formed into one body; as a corporation aggregate, which is one formed of a number of natural persons; the union of individual charges make an aggregate charge.
Pleiotropy describes the genetic effect of a single gene on multiple phenotypic traits. The underlying mechanism is that the gene codes for a product that is, for example, used by various cells, or has a signaling function on various targets.A classic example of pleiotropy is the human disease phenylketonuria (PKU).nsourced material may be challenged and removed. (September 2013). Pleiotropy occurs when one gene influences two or more seemingly unrelated phenotypic traits, an example being phenylketonuria, which is a human disease that affects multiple systems but is caused by one gene defect.
Pleiotropy should not be confused with polygenic traits, in which multiple genes converge to result in a single phenotype. In some instances of pleiotropy, the influence of the single gene may be direct. For example, if a mouse is born blind due to any number of single-gene traits (Chang et al., 2002), it is not surprising that this mouse would also do poorly in visual learning tasks.leiotropy should not be confused with polygenic traits, in which multiple genes converge to result in a single phenotype. In some instances of pleiotropy, the influence of the single gene may be direct. For example, if a mouse is born blind due to any number of single-gene traits (Chang et al.