Marfan syndrome (also called Marfan's syndrome) is a genetic disorder of connective tissue. It has a variable clinical presentation, ranging from mild to severe systemic disease. The most serious manifestations involve defects of the heart valves and aorta, which may lead to early death if not properly managed.
noun. 1  a big deal. 2  See more words with the same meaning: exclamations (list of) . 3  See more words with the same meaning: unimportant, useless.
matters or things that are very unimportant, inconsequential, or nonessential; trifles; trivialities. [1900â05; pseudo-Latin trivia (neuter pl.), taken as the base of trivial] 1  factlet - A piece of trivia.  inconsequentia - Trifling facts or trivia.