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Brinzolamide is a carbonic anhydrase inhibitor which has been found to be effective in lowering the elevated intraocular pressure associated with ocular hypertension and glaucoma. The distribution coefficient, IC50 and Ki values for brinzolamide are 6.56, 3.19 nM and 0.13 nM respectively.
13 FSM in the treatment of glaucoma is designed to help lower thepressure, improve blood flow to the optic nerve and to remove toxinsin the eye. The goal in traditional glaucoma treatment is to lower thepressure inside the eye thus enabling the optic nerve to have greaterblood flow.