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The narcotic in both medications is the oxycodone, the only difference between the two is the additiâ¦on of Tylenol (aka acetaminophen). The addition of Tylenol does not necessarily make the combo drug more powerful than the straight oxycodone, but is an adjunctive therapy so to speak.
Oxycodone and hydrocodone are both opioid pain relievers. They are both extremely potent and are used for moderate to severe pain. Oxycodone is stronger than hydrocodone. Oxycodone is a C-II controlled substance, while hydrocodone is a C-III controlled substance. A C-II medication typically has more addictive potential than a C-III medication.