Social exclusion (or marginalization) is social disadvantage and relegation to the fringe of society.It is a term used widely in Europe, and was first used in France. It is used across disciplines including education, sociology, psychology, politics and economics.ocial exclusion (or marginalization) is social disadvantage and relegation to the fringe of society.
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is thought to be caused by trauma to dentoalveolar structures that have a limited capacity for bone healing due to the effects of bisphosphonate therapy. See the image below. Exposed, necrotic bone in the left anterior maxilla.
Bisphosphonates appear to slow the natural process of removal and replacement of bone, which for the repair process of bone in the jaws is vital; this change in rate of healing of the jaw appears to be related to jaw bone death.