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The half-life of the Metoprolol is between 3 to 7 hours... Read More. Metoprolol side effects usually include dry mouth, constipation, heartburn, vomiting, diarrhea, decreased sex drive, impotence, or difficulty having an orgasm, headache, drowsiness, tired feeling, sleep problems or anxiety and nervousness.
The recommended starting dose of metoprolol succinate extended-release tablets is 25 mg once daily for two weeks in patients with NYHA Class II heart failure and 12.5 mg once daily in patients with more severe heart failure.