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Dihydroergotamine is used to treat migraine headaches and cluster headaches. It is not recommended for migraines that affect only one side of the brain (hemiplegic migraine) or the base of the brain /neck area (basilar migraine), or to prevent migraines from occurring.
In 1943 came the next step for ergot treatment â DHE, the long name being dihydroergotamine. It was first used at the Mayo Clinic. Yes, 1943. Since then, our understanding of migraine has been completely transformed. And yet, some people are still using DHE to stop migraine attacks.