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Brinzolamide is a carbonic anhydrase inhibitor which has been found to be effective in lowering the elevated intraocular pressure associated with ocular hypertension and glaucoma. The distribution coefficient, IC50 and Ki values for brinzolamide are 6.56, 3.19 nM and 0.13 nM respectively.
It is of special concern to people older than 40 years of age. Although glaucoma is sometimes treated surgically, pressure in the eye can usually be reduced, and blindness prevented, through use of eyedrops. Frequently prescribed drugs for this purpose are timolol, betaxolol, dorzolamide, and latanoprost.