âº They act as a framework along which motor proteins can move structures in the cell. Microtubules are assembled from molecules of the protein tubulin. Tubulin is a dimerâa molecule made up of two monomers. The polypeptide monomers that make up this protein are known as a-tubulin and b-tubulin.
Prior to initiation of cefuroxime therapy, careful inquiry should be made concerning previous hypersensitivity reactions to cephalosporins, penicillins, or other drugs. Cefuroxime axetil /is/ contraindicated in patients who are hypersensitive to cefuroxime or other cephalosporins and should be used with caution in patients with a history of hypersensitivity to penicillins.
In the penicillin allergic individual, cefaclor (Ceclor), loracarbef (Lorabid), clarithromycin (Biaxin), azithromycin (Zithromax), sulfamethoxazole (Gantanol), trimethoprim (Bactrim, Septra) and other antibiotics may be used as first choices.