Aerodynamics first: The altitude factor of $c_l \cdot Ma^2$ tells you how much lift can be produced at a given flight Mach number, and the wing loading then gives you the minimum density for sustained flight. 0.4 is a good value for $c_l \cdot Ma^2$, and 30 kg/m$^2$ is a feasible wing loading for flight at 30 km.
Get worse with activity and improve with rest. Myasthenia gravis (MG) can affect any of the muscles that you control voluntarily. It can affect muscles of the face, hands, eyes, arms and legs and those muscles involved in chewing, swallowing and talking. Muscles that control breathing and neck movement also can be affected.
The hallmark of myasthenia gravis is muscle weakness that increases during periods of activity and improves after periods of rest. Certain muscles such as those that control eye and eyelid movement, facial expression, chewing, talking, and swallowing are often, but not always, involved in the disorder.yasthenia gravis is caused by the body's antibodies impairing transmission of nerve impulses to muscles, resulting in fluctuating weakness and fatigue. Acute attacks can be life threatening because of swallowing or breathing difficulties.