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Causes of Cross-eyed. Some of the causes of Cross-eyed are included in the list below: 1  Weak eye muscles. 2  Eye muscle paralysis (see Paralysis symptoms). 3  Eye muscle disease. 4  Eye muscle nerve disorders. 5  Eye vision disorder-especially if the eyes are affected differently.
Strabismus (crossed eyes) is the most common cause of amblyopia. There is often a family history of this condition. The term lazy eye refers to amblyopia, which often occurs along with strabismus. However, amblyopia can occur without strabismus. Also, people can have strabismus without amblyopia.