Evidence for the use of low frequency ultrasound to treat wounds is limited and consists of studies that lack adequate. sample sizes and proper control groups. Additional research with larger trials is needed to demonstrate that low. frequency ultrasound is beneficial for health outcomes in patients with wounds.
The neurotransmitter, acetylcholine, once it has diffused into the synapse, binds to the nicotinic acetylcholine receptors, which are found in the motor end plate. These receptors are ligand-gated ion channels, and once acetylcholine has binded to the receptors, it causes the channels to open.
Figure 1: Left: Schematic representation of the muscle-type nicotinic acetylcholine receptor, view from the synaptic cleft (upper view) and laterally (membrane represented in blue). The ACh binding sites (red) and the ion channel (green arrow) are shown.he nicotinic acetylcholine receptor (nAChR), a key player in neuronal communication, converts neurotransmitter binding into membrane electrical depolarization. This protein combines binding sites for the neurotransmitter acetylcholine (ACh) and a cationic transmembrane ion channel.