Tell your doctor if any of the following side effects become severe or don't go away: 1  Mild itching, burning, stinging, or tingling skin. 2  Redness or soreness. 3  Increased sensitivity to hot or cold temperatures. 4  Acne. 5  Muscle or back pain. 6  Headache. 7  Flu-like symptoms. 8  Runny or stuffy nose. 9  Nausea.
The Krebs cycle, which is also known as the citric acid cycle or tricarboxylic acid cycle, is part of a series of chemical reactions that organisms use to break food down into a form of energy that cells can use.
This is the most important link to the electron transport chain where most of the ATP needed for energy reactions is produced. The initiating step of the citric acid cycle occurs when a four carbon compound (oxaloacetic acid) condenses with acetyl CoA (2 carbons) to form citric acid (6 carbons). The source of acetyl CoA is glycolysis or the fatty acid spiral. As the cycle proceeds, 2 carbons are converted into two CO2 molecules at steps 5 and 6. Another important aspect is the series of oxidation reactions which are accompanied by the loss of hydrogen and electrons at four specific places.