The wart is frozen until it and 1 to 2 mm of surrounding skin have turned white (Figure 15) . A repeat freeze after thawing causes more effective tissue destruction than a single freeze. The affected tissue turns red or blisters over the next one to two days, then gradually sloughs off over the following weeks.
Hermana is in Spanish. It is the Spanish word for sister..
Hermansky-Pudlak syndrome is another rare pigmentation disorder. It is an inherited autosomal recessive disease that results from the abnormal formation of intracellular vesicles and is linked to defects in 8 different genes. Its manifestations include a form of albinism that often presents as freckles or lentigines.