Co-translational folding of a nascent protein and refolding of a denatured protein are fundamentally different processes. Refolding involves the rearrangement of segments of full-length proteins, the conformation of which is in a state of disarray that is dependent on the denaturant and conditions.efore proceeding, it is necessary to define ânascentâ and âco-translationalâ in the sense that these terms will be used. We use the term nascent peptide or nascent protein to mean peptidyl-tRNA bound to the peptidyl transferase center of a ribosome.
reposition - depositing in a warehouse; they decided to reposition their furniture in a recommended repository in Brooklyn; my car is in storage; publishers reduced print runs to cut down the cost of warehousing
Once an old idea is overturned, selling the new idea is often ludicrously simple. As a matter of fact, people will often actively search for a new idea to fill the void. Never be afraid of conflict either. The crux of a repositioning program is undercutting an existing concept, product, or person. Conflict, even personal conflict, can build a reputation overnight.