NSAIDs work by reducing the production of prostaglandins, chemicals that cause pain, fever and inflammation. NSAIDs block the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower production of prostaglandins. As a consequence, inflammation, pain and fever are reduced.
Medical Definition of BILIRUBIN. : a reddish yellow pigment C33H36N4O6 that occurs especially in bile and blood and causes jaundice if accumulated in excess.
THE LIVER CHANGES IT INTO A WATER-SOLUBLE SUBSTANCE CALLED BILIRUBIN. WHEN THERE IS A BLOCKAGE OR DISORDER WITH THE LIVER OR GALL BLADDER DUCTS BILIRUBIN MAY NOT BE ABLE TO GET TO THE SMALL INTESTINE AND CAN CAUSE JAUNDICE. THE BODY WILL TRY TO GET RID OF THE EXTRA BILIRUBIN THROUGH URINE.