Synonyms: Freiberg's infraction. This is a rare disease characterised by osteonecrosis of the second metatarsal head, most commonly seen in teenage girls. It was first described in 1914 by Alfred H. Freiberg.It is difficult to ascertain the true incidence of Freiberg's disease, as many cases may resolve spontaneously before treatment has been sought.his is a rare disease characterised by osteonecrosis of the second metatarsal head, most commonly seen in teenage girls. It was first described in 1914 by Alfred H. Freiberg. It is difficult to ascertain the true incidence of Freiberg's disease, as many cases may resolve spontaneously before treatment has been sought.
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