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Summary. 1  Ambien and Lunesta are both prescription drugs intended for the treatment of insomnia. 2  Both can be availed of in tablet form. 3  Ambien and Lunesta have an immediate sedative effect that last 7-8 hours per dosage.  Ambienâs efficacy last up to 35 days, while Lunesta remains effective up to 6 months.
Ambien is also much more widely available and easily accessible than rohypnol, the drug usually associated with date rape. Ambien is an effective sleep aid and a huge money maker for its manufacturer. Most people take it as prescribed and treat their insomnia successfully with no problems.