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Brinzolamide is a carbonic anhydrase inhibitor which has been found to be effective in lowering the elevated intraocular pressure associated with ocular hypertension and glaucoma. The distribution coefficient, IC50 and Ki values for brinzolamide are 6.56, 3.19 nM and 0.13 nM respectively.
It is the first drug of its class to be used for glaucoma. Brimonidine was approved by the FDA in 1996. PRESCRIBED FOR: Brimonidine is used for the reduction of intraocular pressure in patients with open-angle glaucoma. SIDE EFFECTS: Common side effects include: 1  dry eyes, 2  red eyes,  irritation of the eyes,