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You and your doctor have to decide this. Most people take the medicine for 12 weeks or more. Naltrexone only has to be taken once a day. Be sure to take naltrexone just the way your doctor tells you to. Don't take extra pills, don't skip pills and don't stop taking pills until you talk to your doctor.
Antagonist Pharmacotherapy. Naltrexone is an opioid antagonist that blocks the effects of heroin and most other opioids. It does not have addictive properties or produce physical dependence, and tolerance does not develop. It has a long half-life, and its therapeutic effects can last up to 3 days.Naltrexone is not a stigmatized treatment.he antagonist blocks the receptor and prevemts activation by neurotransmitters or other drugs. So in the case of opiates, lets look at the opiate agonist, morphine. When morphine enters the brain, it binds to opiate receptors and activates them. This binding is what produces the effects of Morphine.