In our practice, we discontinue progesterone supplementation between 9 and 12 weeks of gestation. Available evidence suggests that the most common forms of progesterone supplementation are safe in early pregnancy.
Insulinoma in Dogs. Insulinomas are malignant neoplasms -- fast growing cancer cells -- of the beta cells in the pancreas. The beta cells primarily secrete insulin, among other hormones. Insulin produces a variety of effects in the body -- the primary one being to regulate glucose levels throughout the body's cells.
If a tumor grows slowly, this is not necessarily a problem for a dog, especially in older animals. Such a tumor may take so long to reach a point where it is a problem, the animal may eventually pass from other age-related complications before cancer even presents health issues.