The carrier frequency and incidence of alpha thalassemia vary by the type and population. Carrier frequency of this condition is reported to be the highest in individuals of Southeast Asian, African, West Indian, and Mediterranean descent.
Clitheroe Castle Museum is adjacent to the castle. The castle was listed as a Scheduled Monument on 10 April 1915 (and later, under the Ancient Monuments and Archaeological Areas Act 1979 law).It was Grade I listed on 19 May 1950.t has been suggested that Clitheroe Castle may have been first built before 1086 as there is reference to the  castellatu Rogerii pictaviensis  in the Domesday Book entry for nearby Barnoldswick. However, it is likely the passage refers to another castle.
A motte and bailey castle, often spelled as motte-and-bailey, is an early type of castle. They were the first type of castle to be built in England. The castle is made up of two parts.The motte is a raised mound or earthwork which would have a stone or wooden keep on top. A keep is a kind fortified tower. The bailey is an enclosed courtyard that was protected by a ditch and a palisade â which is a wall made from wooden stakes. motte and bailey castle, often spelled as motte-and-bailey, is an early type of castle. They were the first type of castle to be built in England. The castle is made up of two parts.