In mammals, the corresponding gene is SIRT1, a principal modulator of pathways, also activated by CR, that improve control of glucose homeostasis, insulin sensitivity and vascular function; boost endurance; and inhibit tumor formation.
Durian Perangin Waterfall is located in northeastern Langkawi, surrounded by lush greenery and natural rocks formations. This 14-tier waterfall tumbles down Mount Raya, the highest mountain on the island, into a crystal clear lake at the bottom.
Kuah Town on Langkawi Island. Kuah is the most important town on Langkawi Island. Though it is not an actual city, local people from Langkawi refer to it as a city. Kuah is a nice and small town with a relaxed atmosphere. There are no big malls, no heavy traffic and also no places to eat on every corner.