Providers may obtain provider enrollment forms by contacting the Out-of-State Provider Unit at (916) 636-1960 for forms to be mailed or by downloading the appropriate forms from the Medi-Cal website's Provider Enrollment webpage.
Humans carry one to two lethal recessive mutations on average, study estimates Posted on April 8, 2015 by Kevin Jiang Humans carry on average one to two mutations that, if inherited from both parents, can cause severe genetic disorders or death before reaching reproductive age, report scientists from the University of Chicago and Columbia University.
Mutation rates were calculated for a range of different human-chimpanzee divergence times and for two different ancestral population sizes. Mutation rate estimates vary from 1.3 x 10-8 (assuming T = 6 mya and Ne = 105) to 2.7 x 10-8 (assuming T = 4.5 mya and Ne = 104). divergence date of 6 million years gave rise to a human per-site mutation rate of 0.65 x 10 -9 per year (1.3 x 10 -8 per 20-year generation). A divergence date of 7 million years lowered the mutation rate to 0.57 x 10 -9 per year. Low mutation rates do not always result from these studies.