The first term determines the nature of the drug's effect and how much drug is needed at the site of action to engage that site to a clinically meaningful extent in the usual patient. The second term in the equation determines the magnitude of the drug's effect by determining how much drug reaches the site of action.
Tsuki (çªã) , is the Japanese word for thrust, coming from the verb tsuku (çªã) , meaning to thrust. The second syllable is accented, with Japanese's unvoiced vowels making it pronounced almost like  ski  (but preceded by a t sound).
 Tanuki  is often mistakenly translated into English as  badger  or  raccoon  (as used in the US version of the movie Pom Poko, and outlined in Tom Robbins ' book Villa Incognito), two unrelated types of animals with a superficially similar appearance.he Japanese Raccoon Dog (Nyctereutes procyonoides viverrinus), also known as tanuki (ç¸ or ãã¬ã) in Japanese, is a subspecies of the Asian raccoon dog.