The first term determines the nature of the drug's effect and how much drug is needed at the site of action to engage that site to a clinically meaningful extent in the usual patient. The second term in the equation determines the magnitude of the drug's effect by determining how much drug reaches the site of action.
Tsuki (çªã) , is the Japanese word for thrust, coming from the verb tsuku (çªã) , meaning to thrust. The second syllable is accented, with Japanese's unvoiced vowels making it pronounced almost like  ski  (but preceded by a t sound).
In Japan, the crane or tsuru, is a national treasure. It is the symbol of longevity and good luck because it was thought to have a life span of a thousand years. Tsuru are also monogamous, therefore, often used for wedding decor.lthough there are many species of cranes, in Asia itâs usually the red crown crane that is depicted. The long white neck and torso, contrasting black legs and head is topped with a red crown. Their physical beauty is undeniable.. According to Wikipedia, the crane is the worldâs tallest flying bird.