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A gyro sandwich consists of various rotisseried meats, salad vegetables such as tomatoes, lettuce and onions, along with a yogurt-based tzatziki sauce. These ingredients are placed on a hearty form of grilled pita bread and served as a wrap sandwich. In some countries, it may also contain french fries or mustard.
Best Answer: Gyro is a ground meat mixture, formed into a loaf, then grilled and thinly sliced. Souvlaki is cubes of meat (usually chicken, lamb or pork), usually skewered and grilled, like kababs (http://en.wikipedia.org/wiki/Souvlaki). I've made Alton Brown's gyro recipe, it's pretty good for a home made version: http://www.foodnetwork.com/recipes/alton-brown/gyro-meat-with-tzatziki-sauce-recipe/index.html.