medication interactions exist: (1) pharmacokinetic interactions, in which alcohol interferes. with the metabolism of the medication, and (2) pharmacodynamic interactions, in which. alcohol enhances the effects of the medication, particularly in the central nervous system. (e.g., sedation).
It is also known by its drug name, Celecoxib. Celebrex is used to treat pain, stiffness and discomfort caused by lupus in joints and other tissues. Unlike other drugs in its class, Celebrex does not interfere with blood clotting. Celebrex should not be used by people who are allergic to nonsteroidal anti-inflammatory drugs (NSAIDs) such as Aspirin or Ibuprofen.
Cardiovascular Thrombotic Events. 1  Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction, and stroke, which can be fatal.  CELEBREX is contraindicated in the setting of coronary artery bypass graft (CABG) surgery.