In mammals, the corresponding gene is SIRT1, a principal modulator of pathways, also activated by CR, that improve control of glucose homeostasis, insulin sensitivity and vascular function; boost endurance; and inhibit tumor formation.
Durian Perangin Waterfall is located in northeastern Langkawi, surrounded by lush greenery and natural rocks formations. This 14-tier waterfall tumbles down Mount Raya, the highest mountain on the island, into a crystal clear lake at the bottom.
Sun, sand and sea on the beach. Langkawi,(Jawi:ÙØ§ÙÙØ§ÙÙ ) officially known as Langkawi, the Jewel of Kedah (Malay: Langkawi Permata Kedah) is an archipelago of 99 islands (an extra 5 temporary islands are revealed at low tide) in the Andaman Sea, some 30 km off the mainland coast of northwestern Malaysia.