In turn, its influence on the reward circuit can lead a user to bypass survival activities and repeat drug use. Chronic cocaine use can lead to a cocaine addiction and in some cases damage the brain and other organs. An addict will continue to use cocaine even when faced with adverse consequences.
vasodilator (vÄÂ´zÅdÄ«Â´lÄtur), n 1. an agent that causes dilation of the blood vessels. n 2. a drug that relaxes the smooth muscle walls of the blood vessels and increases their diameter.
They may act by activation of the vasomotor center in the brain, which brings about relaxation of the smooth muscle in the blood vessel walls or they can act locally on blood vessel smooth muscle cells. Vasodilators are used to treat hypertension, angina and congestive heart failure.