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Concerns. Having high blood calcium levels and taking multiple calcium or vitamin D supplements can result in hypercalcemia over time. High calcium levels can interfere with muscle contractions, hormone levels and brain functioning.Consult with your physician if you think you have taken too much calcium.alcium tablets can cause headaches if taken in excess. Photo Credit Thinkstock/Comstock/Getty Images. Even though vitamins are important to your health, multivitamins and vitamin supplements can cause side effects. Some supplements cause side effects in normal doses, and others cause side effects in excessive doses.
Hypercalcemia. Hypercalcemia is an elevated calcium level in the blood. Hypercalcemia can be asymptomatic in laboratory results, but high calcium levels are often an indicator of multiple myeloma. Hypercalcemia related to multiple myeloma is caused by the breakdown of bone which leads to the release of calcium into the blood. This can be a serious problem if appropriate treatment is not given immediately. Severe hypercalcemia can result in coma or cardiac arrest. Symptoms of hypercalcemia include the following: â¢ Loss of appetite