When the wheel bearing goes bad, you will notice several symptoms. 1  Listen carefully. 2  The most common and often most-identifiable symptom associated with a bad wheel bearing is noise coming from the wheel or tire area of the moving vehicle.
Rare Disease Day takes place on the last day of February each year. The main objective of Rare Disease Day is to raise awareness amongst the general public and decision-makers about rare diseases and their impact on patients' lives. The campaign targets primarily the general public and also serarediseaseday.org.
A rare disease is generally considered to be a disease that affects fewer than 200,000 people in the United States at any given time. Rare diseases are also sometimes called orphan diseases. How many rare diseases are there? There are more than 6,800 rare diseases. Altogether, rare diseases affect an estimated 25 million to 30 million Americans. Top of page. What causes rare diseases? The exact cause for many rare diseases remains unknown. Still, for a significant portion, the problem can be traced to mutations (changes) in a single gene. Such diseases are referred to as rare, genetic diseases. Many of these genetic mutations can be passed on from one generation to the next, explaining why certain rare diseases run in families. It is important to keep in mind that genetics are just one piece of the puzzle.