Plasma half-life (T1/2) of unchanged lorazepam in the patient group (11.3 +/- 0.6 h) was not different from that obtained in normals (11.1 +/- 0.9 h).rinary excretion of lorazepam-glucuronide was found to be considerably decreased in chronic renal failure associated with accumulation of high concentrations of this conjugate in plasma during days after a single oral dose. The plasma T1/2 of this conjugate in normals was 20.7 +/- 2.1 h.
A: Microfilaments are the thinnest filament of a eukaryotic cell's cytoskeleton. The linear microfilament chains are composed of actin proteins, which are flexible and relatively strong. A cell's cytoskeleton is a cellular scaffolding consisting of these actin microfilaments, along with intermediate filaments and microtubules. Continue Reading
Microfilaments function to keep cell shape. They also play a crucial role in muscle cell contraction, essential to the ability of your skeleton and muscle systems to work together and throw and catch a football.