Signaling begins with the binding of a TGF beta superfamily ligand to a TGF beta type II receptor. The type II receptor is a serine/threonine receptor kinase, which catalyzes the phosphorylation of the Type I receptor. Each class of ligand binds to a specific type II receptor.
The Akabane virus is an insect-transmitted virus that causes congenital abnormalities of the central nervous systems in ruminants.wo viruses, both arthropod borne, have been implicated in the cause of these congenital defects: Akabane virus, named after the district in Japan where it was first found, and Aino virus. Generally, both these viruses are referred to as Akabane virus.
Akathisia or acathisia is a movement disorder that may be a side effect of certain drugs that are often prescribed for people with bipolar disorder. This side effect is often not properly recognized and is a kind of subtle response when taking certain kinds of drugs that are designed to treat psychiatric disorders.