In biology, the active site is the region of an enzyme where substrate molecules bind and undergo a chemical reaction. The active site consists of residues that form temporary bonds with the substrate (binding site) and residues that catalyse a reaction of that substrate (catalytic site).
Seattle is rolling out 11 rainbow crosswalks in Capitol Hill this week, adding a colorful bang to the annual Pride celebration. The crosswalks cost the city $66,000, said Seattle Department of Transportation spokesman Rick Sheridan, and are permanent.
In 2009, the U.S. Government Accountability Office pegged pedestrian fencing costs at $400,000-$15.1 million per mile, averaging $3.9 million per mile. Vehicle fencing â barriers set in remote areas to prevent vehicles from crossing the borderâ ranged from $200,000 to $1.8 million per mile, the office reported.