One common cause of SLUDGE is exposure to organophosphorus insecticides (including parathion, malathion, and diazinon) or nerve gas, such as sarin. These agents phosphorylate acetylcholinesterase, thereby irreversibly deactivating acetylcholinesterase and raising acetylcholine levels and causing SLUDGE.
Every stone grants different abilities to its owner. The Infinity Gems (previously known as Soul Gems) are some of the most powerful artifacts in the Universe. Each one allows its owner complete omnipotence over one aspect of the universe: time, space, reality, mind, power, and soul. When all six are directly wielded together, nothing is impossible for their bearer.
The gems boost by the most, but only last for one use. The plates, items, and the incenses boost by 20%. So, for example, the Mind plate, Twisted spoon and Odd incense would boost the power of psychic moves by the same amount. Then there's life orb, which boosts the holders attacking stat by 1.3x. Life orb would be superior to all the plates, items, and incenses, but has the drawback of costing 10% HP per shot. Muscle band and Wise glasses boost the power of all physical or special attacks by 10% respectively.