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Singulair side-effects do not include direct weight loss or weight gain. Side effects that may occur include headache, weakness, tiredness, trouble sleeping, cough, dizziness, indigestion, nausea or stomach upset and a stuffy nose.
Actos can cause other serious side effects including: Weight gain. Pioglitazone, the medicine in Actos can cause weight gain that may be due to fluid retention or extra body fat. Weight gain due to fluid retention can be a serious problem for people with certain conditions, including heart problems. Liver problems.