In mammals, the corresponding gene is SIRT1, a principal modulator of pathways, also activated by CR, that improve control of glucose homeostasis, insulin sensitivity and vascular function; boost endurance; and inhibit tumor formation.
Durian Perangin Waterfall is located in northeastern Langkawi, surrounded by lush greenery and natural rocks formations. This 14-tier waterfall tumbles down Mount Raya, the highest mountain on the island, into a crystal clear lake at the bottom.
Head up the thrilling new cable car to the summit of Mount Mat Cincang - Langkawi's second highest mountain - for an unrivalled view of the entire main island and beyond. Other popular destinations are the Field of Burnt Rice, Hot Springs, Telaga Tujuh (The Seven Wells) and the Beach of Black Sand.