In turn, its influence on the reward circuit can lead a user to bypass survival activities and repeat drug use. Chronic cocaine use can lead to a cocaine addiction and in some cases damage the brain and other organs. An addict will continue to use cocaine even when faced with adverse consequences.
vasodilator (vÄÂ´zÅdÄ«Â´lÄtur), n 1. an agent that causes dilation of the blood vessels. n 2. a drug that relaxes the smooth muscle walls of the blood vessels and increases their diameter.
a nerve or agent that causes dilation of blood vessels by promoting the relaxation of vascular smooth muscle. Chemical vasodilators include hydralazine, nitroglycerin, nitroprusside, nesiritide, and trimethaphan. They have been useful in the treatment of acute heart failure in myocardial infarction, in cases associated with severe mitral regurgitation, and in failure resulting from myocardial disease.