The rate for the last 1/3 of the taper should be reduced to  of that for the first 2/3. Clonazepam is one of the nitro-benzodiazepines series, i.e. nitrazepam, flunitrazepam, clonazepam, and nimetazepam. It has a half-life of 20-50 hours and accumulates from 1.5 to 3 times the daily dose level.
Noun. 1. myeloma-a tumor of the bone marrow (usually malignant) composed of cells normally found in bone marrow. malignant neoplasm, malignant tumor, metastatic tumor-a tumor that is malignant and tends to spread to other parts of the body.
Multiple myeloma is a disseminated malignancy of monoclonal plasma cells that accounts for 1.3% of all malignancies and 15% of hematologic cancers. The incidence has been increasing by 0.7% each year for the last 10 years while mortality has come down by 1.7% each year over the same period.