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Finally, with further decreases in the levels of CD4 cells, the person develops AIDS. According to the CDC, for an HIV-infected person, some signs that AIDS has developed (known as AIDS-defining conditions) are: The CD4 cell count has decreased to fewer than 200 cells per cubic milliliter of blood.
HIV affects specific cells of the immune system, called CD4 cells, or T cells. Over time, HIV can destroy so many of these cells that the body canât fight off infections and disease. When this happens, HIV infection leads to AIDS.