One common cause of SLUDGE is exposure to organophosphorus insecticides (including parathion, malathion, and diazinon) or nerve gas, such as sarin. These agents phosphorylate acetylcholinesterase, thereby irreversibly deactivating acetylcholinesterase and raising acetylcholine levels and causing SLUDGE.
Every stone grants different abilities to its owner. The Infinity Gems (previously known as Soul Gems) are some of the most powerful artifacts in the Universe. Each one allows its owner complete omnipotence over one aspect of the universe: time, space, reality, mind, power, and soul. When all six are directly wielded together, nothing is impossible for their bearer.
An aspect of Skyrim's game play is the use of soul gems, and item enchantment. The game does explain how enchanting and soul gems work, but not in great depth. Contents (use the Control+F command to quickly find the info you need!) :: 1. General Soul Gem Info. 2. Black Soul Gems and Azura's Star.