In biology, the active site is the region of an enzyme where substrate molecules bind and undergo a chemical reaction. The active site consists of residues that form temporary bonds with the substrate (binding site) and residues that catalyse a reaction of that substrate (catalytic site).
Seattle is rolling out 11 rainbow crosswalks in Capitol Hill this week, adding a colorful bang to the annual Pride celebration. The crosswalks cost the city $66,000, said Seattle Department of Transportation spokesman Rick Sheridan, and are permanent.
Professional installation of a flagstone walkway can cost $10-$25 or more a square foot for dry-set (on a bed of sand or gravel) and $20-$40 or more a square foot for wet-set one (mortared on a slab of reinforced concrete) , depending on local rates and the complexity of the project, or about $1,000-$2,500 for a dry-laid walkway and $2,000-$6,000 or ...