5-FU injection and topical even in small doses cause both acute central nervous system (CNS) damage and progressively worsening delayed degeneration of the CNS in mice. This latter effect is caused by 5-FU-induced damage to the oligodendrocytes that produce the insulating myelin sheaths.
Home > Sexually transmitted infections > Syphilis > After treatment for syphilis. It is strongly advised that you do not have any sexual intercourse; including vaginal; anal or oral sex until you and your partner(s) have both finished the treatment and any follow-up treatment.
If syphilis is not treated during the primary stage, it often progresses to later stages. In the secondary stage of syphilis, a skin rash will usually develop about 2 to 12 weeks after the chancre appears. The symptoms usually disappear without treatment within 2 months. After the rash clears, a person may have a period with no symptoms. This symptom-free period is called the latent (hidden) stage.