When the wheel bearing goes bad, you will notice several symptoms. 1  Listen carefully. 2  The most common and often most-identifiable symptom associated with a bad wheel bearing is noise coming from the wheel or tire area of the moving vehicle.
Rare Disease Day takes place on the last day of February each year. The main objective of Rare Disease Day is to raise awareness amongst the general public and decision-makers about rare diseases and their impact on patients' lives. The campaign targets primarily the general public and also serarediseaseday.org.
Most rare diseases are genetic, and thus are present throughout the person's entire life, even if symptoms do not immediately appear. Many rare diseases appear early in life, and about 30 percent of children with rare diseases will die before reaching their fifth birthday. With a single diagnosed patient only, ribose-5-phosphate isomerase deficiency is considered the rarest genetic disease.