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Typically, the withdrawal duration for a drug like Oxycodone is somewhere between 4 and 14 days. This is true for most opiates except for in the instance when an opiate such as Methadone is being eliminated from the equation in which case the withdrawal symptoms can, and often do, last for weeks.
On average, the oxycodone will take about 19.31 hours to clear from the system. The elimination of another ingredient, acetaminophen is shorter and the half-life usually lasts about 3.1 hours, which means that the acetaminophen will leave the system in about 17 hours. It can be shorter in some individuals where it is estimated about 11 hours where the half-life is approximately 2 hours. The full clearance of Percocet will leave the system in 24 hours which can be sometimes longer, up to 48 hours for some people.