The gross monthly average income is based on data supplied by Statistics New Zealand to the International Labour Organization [9]. The average income includes the salaries and wages of paid employees. Employees include both men and women unless otherwise noted.
The Posterior Reversible Encephalopathy Syndrome (PRES) is a serious complication of treatment with cyclosporine with an incidence of 8% in patients with bone marrow transplantation. PRES is a hypertensive encephalopathy with a various clinical presentations (twitching, convulsions, blindness and coma). Cyclosporine is an immunosuppressant used in the prevention of graft rejection in solid organ transplantation and prevention of Graft Versus Host Disease
Cyclosporine is a Calcineurin Inhibitor Immunosuppressant. The mechanism of action of cyclosporine is as a Calcineurin Inhibitor, and Cytochrome P450 3A4 Inhibitor, and P-Glycoprotein Inhibitor. Cyclosporine is a natural cyclic polypeptide immunosuppressant isolated from the fungus Beauveria nivea. The exact mechanism of action of cyclosporine is not known but may involve binding to the cellular protein cytophilin, resulting in inhibition of the enzyme calcineurin. This agent appears to specifically and reversibly inhibit immunocompetent lymphocytes in the G0-or G1-phase of the cell cycle.