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Researchers say consumption of artificial sweeteners such as saccharin, sucralose and aspartame led to increased risk of glucose intolerance, a condition linked to diabetes. Sweet âN Low contains saccharin. Equal original contains aspartame. Splenda contains sucralose.
Still unclear is whether itâs healthier to swap sugar for sugar substitutes. Recent research shows that artificial sweeteners are not inert â they alter human metabolism and gut bacteria and may be linked to Type-2 diabetes. Itâs helpful to understand how the body processes diet drinks and Splenda-sweetened lattes.