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(However, for many people, eating lysine-rich foods may provide enough lysine that supplements may not be needed.) The typical dosages used range from a low of 500 mg (0.5 g) daily to 1,000 mg (1 g) three times daily. Some experts have even suggested dose as high as 3,000 mg (3 g) three times daily for severe outbreaks.
A Stacy Wiegman, PharmD , Pharmacy, answered. If you are taking lysine, follow your doctor's instructions or the directions on the package label regarding maximum daily dose. Since the US Food and Drug Administration (FDA) has not approved lysine to treat any condition, the maximum daily dose has not been described.