One common cause of SLUDGE is exposure to organophosphorus insecticides (including parathion, malathion, and diazinon) or nerve gas, such as sarin. These agents phosphorylate acetylcholinesterase, thereby irreversibly deactivating acetylcholinesterase and raising acetylcholine levels and causing SLUDGE.
Every stone grants different abilities to its owner. The Infinity Gems (previously known as Soul Gems) are some of the most powerful artifacts in the Universe. Each one allows its owner complete omnipotence over one aspect of the universe: time, space, reality, mind, power, and soul. When all six are directly wielded together, nothing is impossible for their bearer.
The gem can fit a grand soul and while you can not remove it from your inventory and it's not capable for use in enchanting, it can be used to recharge enchanted weapons, removing it as if it was a normal soul gem. Found in Wylandriah's Satchel, under the stairs to the first floor on top of a barrel.