Signaling begins with the binding of a TGF beta superfamily ligand to a TGF beta type II receptor. The type II receptor is a serine/threonine receptor kinase, which catalyzes the phosphorylation of the Type I receptor. Each class of ligand binds to a specific type II receptor.
The Akabane virus is an insect-transmitted virus that causes congenital abnormalities of the central nervous systems in ruminants.wo viruses, both arthropod borne, have been implicated in the cause of these congenital defects: Akabane virus, named after the district in Japan where it was first found, and Aino virus. Generally, both these viruses are referred to as Akabane virus.
Aka Island (é¿åå³¶, Aka-jima) is an island in the Pacific Ocean and is part of the Kerama Islands group in Okinawa Prefecture, Japan. The island is commonly known as Aka or Aka-shima and is located some 15 miles to the southwest of Okinawa Island. It has a subtropical climate and a population of approximately 330 people.