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Finally, with further decreases in the levels of CD4 cells, the person develops AIDS. According to the CDC, for an HIV-infected person, some signs that AIDS has developed (known as AIDS-defining conditions) are: The CD4 cell count has decreased to fewer than 200 cells per cubic milliliter of blood.
Aging and HIV/AIDS have drastic effects on the immune system; each lower the production of T cells needed to defend the body against infection. Furthermore, evidence suggests that HIV may accelerate the aging process, and reduce an individual's T-cell count in a similar way to someone who is 20 to 30 years older.