medication interactions exist: (1) pharmacokinetic interactions, in which alcohol interferes. with the metabolism of the medication, and (2) pharmacodynamic interactions, in which. alcohol enhances the effects of the medication, particularly in the central nervous system. (e.g., sedation).
It is also known by its drug name, Celecoxib. Celebrex is used to treat pain, stiffness and discomfort caused by lupus in joints and other tissues. Unlike other drugs in its class, Celebrex does not interfere with blood clotting. Celebrex should not be used by people who are allergic to nonsteroidal anti-inflammatory drugs (NSAIDs) such as Aspirin or Ibuprofen.
Both aspirin and nonsteroidal anti-inflammatory medications (NSAIDs), such as ibuprofen (Motrin IB, Advil, others) and naproxen sodium (Aleve), reduce the clotting action of blood platelets. Regular use of nonsteroidal anti-inflammatory medications can increase your bleeding risk. Some NSAIDs can increase the risk of heart attacks on their own. Additionally, some NSAIDs can adversely interact with aspirin, increasing the risk of bleeding even more. If you need only a single dose of ibuprofen, take it two hours after the aspirin.