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Also, another important concept is that acute lung injury. temporally associated with multiple transfusions can be TRALI, be-. cause each unit of blood or blood component can carry one or more. of the possible causative agents: antileukocyte antibody, biologically. active substances, and other yet unidentiï¬ed agents.
An ideal ratio of ventilation to perfusion (also known as V/Q ratio) is approximately one. If this ratio is less than one (but not zero), hypoxemia caused by this mechanism can develop. Abnormal V/Q ratio in various regions of the lung is the most common cause of hypoxemia in all types of patients. This type of hypoxemia is also common in advanced liver disease due to cirrhosis and hepatic hydrothorax. It responds beneficially to oxygen supplementation given either by face mask or nasal prongs.