In mammals, the corresponding gene is SIRT1, a principal modulator of pathways, also activated by CR, that improve control of glucose homeostasis, insulin sensitivity and vascular function; boost endurance; and inhibit tumor formation.
Durian Perangin Waterfall is located in northeastern Langkawi, surrounded by lush greenery and natural rocks formations. This 14-tier waterfall tumbles down Mount Raya, the highest mountain on the island, into a crystal clear lake at the bottom.
Off the coast of Kedah is a cluster of 99 islands offering the best of many worlds: beautiful beaches, world- class infrastructure, mangroves rich in flora and fauna, ultra- cheap duty-free shopping and fascinating legends. Langkawi has a lingering legend woven into its history.