It is also closely related to the European Red Raspberry (Rubus idaeus), sharing the distinctively white underside of the leaves and fruit that readily detaches from the carpel, but differing in the ripe fruit being black, and in the stems being more thorny.
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Puffer fish contain the potent neurotoxin tetrodotoxin. TTX is thought to be synthesized by a bacterial or dinoflagellate species associated with the puffer fish. The toxin is concentrated in the liver, gonads, and skin. The level of toxicity is seasonal, and, in Japan, fugu is served only from October through March.