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List of 34 causes of Mucus buildup. This section shows a full list of all the diseases and conditions listed as a possible cause of Mucus buildup in our database from various sources. 1  Adenovirus. 2  Allergic rhinitis. 3  Allergies. 4  Antrochoanal polyp. 5  Asthma. 6  Atrophic rhinitis. 7  Bronchitis.
Sinus disease stops the normal flow of mucus from the sinuses to the back of the throat. The tiny hair-like sweepers become blocked when infections or allergies cause tiny nasal tissues to swell. The swelling traps mucus in the sinuses. Some people have bodily defects that contribute to sinus disease.