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Greco-Roman Cultural Matrix: Greece and Rome together constitute a heritage from the beginning of the former to the end of the latter, and this total heritage preserved some aspects of the Ancient Mediterranean legacy while establishing and contributing unique innovations at the same time.
At the beginning of the above outline (around 285), the Greco-Roman culture of the Mediterranean world was still dominant. By the end (around 700), that world had changed in so many respects that we are clearly in a new civilization.