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Humans absorb xylitol slowly, and the sweetener when ingested orally is absorbed at from 50 to 95 percent. However, in dogs, xylitol is rapidly and totally absorbed within about 30 minutes. Just a small amount of xylitol can cause a dangerous insulin surge and a rapid drop in blood sugar. The toxicity of xylitol in dogs is dose-dependent. The dose required to trigger hypoglycemia (low blood glucose) is approximately 0.1 grams/kg, while the amount needed to cause liver failure is about 0.5 grams/kg.
Note: Dr. Bruhn's recommended use of xylitol to rinse the mouth or brush the teeth with, rather than chewing xylitol gum, of course has the additional advantage that one doesn't have to swallow the xylitol (in contrast to gum chewing) when simply rinsing or brushing one's teeth.lternatively, use the xylitol-saliva mix as if it were toothpaste and brush your teeth with it for 3 to 6 minutes. Do not rinse your mouth afterwards, washing out with water markedly reduces xylitol's positive effect.