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â¦â¦..Perfectly Natural. Pyroluria is a genetic disorder that causes anxiety, depression and other mood disorders affecting children right through to adulthood. The onset of Pyroluria usually occurs with a traumatic incident such as moving interstate or becoming unemployed, parental divorce or death of a loved one.yroluria is a blood disorder affecting the way our red blood cells are broken down. In a person with Pyroluria certain by-products from our red blood cells accumulate in the body. These by-products aren't cleared from the body fast enough and end up binding to our nutrients.
Phenylketonuria (PKU) (phenyl + ketone + -uria; /ËfinÉlËkitÉµnËjÊÉriÉ/) is an inborn error of metabolism involving impaired metabolism of phenylalanine, one of the amino acids.Phenylketonuria is caused by absent or virtually absent phenylalanine hydroxylase (PAH) enzyme activity.n people without PKU, the PAH enzyme breaks down any excess phenylalanine from these sources beyond what is needed by the body. However, if there is not enough of the PAH enzyme or its cofactor, then phenylalanine can build up in the blood and brain to toxic levels, affecting brain development and function.