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Individuals most impacted by the rising cost of insulin are the uninsured and the under-insured. These patients are forced to pay the ever-increasing retail sale price (which is increasing due to a variety of factors, including increased wholesale price) or a percentage of this price when buying insulin.
But prices of U-500 and regular human insulin weren't always equal. In 2007, regular Humulin cost $0.04 per unit of insulin -- twice that of the $0.02 price tag on each unit of insulin in U-500.Realizing Potential. Demand for U-500 began escalating about 5 years ago, in lock-step with a worsening epidemic of obesity and diabetes.n 2007, regular Humulin cost $0.04 per unit of insulin -- twice that of the $0.02 price tag on each unit of insulin in U-500. Realizing Potential. Demand for U-500 began escalating about 5 years ago, in lock-step with a worsening epidemic of obesity and diabetes.