In mammals, the corresponding gene is SIRT1, a principal modulator of pathways, also activated by CR, that improve control of glucose homeostasis, insulin sensitivity and vascular function; boost endurance; and inhibit tumor formation.
Durian Perangin Waterfall is located in northeastern Langkawi, surrounded by lush greenery and natural rocks formations. This 14-tier waterfall tumbles down Mount Raya, the highest mountain on the island, into a crystal clear lake at the bottom.
Langkawi Island. Geopark Langkawi is the most Northern archipelago located on the Westside of Peninsular Malaysia; located 30 km off the mainland. The archipelago consists of the main island Langkawi and almost 100 small surrounding islands; only four of them are inhabited.