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Researchers say consumption of artificial sweeteners such as saccharin, sucralose and aspartame led to increased risk of glucose intolerance, a condition linked to diabetes. Sweet âN Low contains saccharin. Equal original contains aspartame. Splenda contains sucralose.
1 Diabetes. 2  Unlike artificial sweeteners, sugar alcohols can raise blood sugar levels because they're carbohydrates. 3  But because your body doesn't completely absorb sugar alcohols, their effect on blood sugar is less than that of other sugars. 4  Different sugar alcohols can affect blood sugar differently.s with artificial sweeteners, the FDA regulates sugar alcohols as food additives. Sugar alcohols used in U.S. manufactured food generally have GRAS status. There are few health concerns associated with sugar alcohols.