Variance. The Variance is defined as: The average of the squared differences from the Mean. To calculate the variance follow these steps: 1  Work out the Mean (the simple average of the numbers). 2  Then for each number: subtract the Mean and square the result (the squared difference).3  Then work out the average of those squared differences.o calculate the variance follow these steps: 1  Work out the Mean (the simple average of the numbers). 2  Then for each number: subtract the Mean and square the result (the squared difference).
Causes of Hormone Imbalance. Hormonal balance is vital to a healthy, cancer-free mind and body, but can be disrupted in many ways. Hormone fluctuations occur naturally, such as in puberty, menopause and perimenopause. Hormone imbalance may also be caused by toxins or an unbalanced lifestyle. Understanding the causes of hormone imbalance empowers us to prevent them, and at the same time, feel better, think better, and better prevent breast cancer.
Hormone diseases also occur if your body does not respond to hormones the way it is supposed to. Stress, infection and changes in your blood's fluid and electrolyte balance can also influence hormone levels. In the United States, the most common endocrine disease is diabetes. There are many others.