In mammals, the corresponding gene is SIRT1, a principal modulator of pathways, also activated by CR, that improve control of glucose homeostasis, insulin sensitivity and vascular function; boost endurance; and inhibit tumor formation.
Durian Perangin Waterfall is located in northeastern Langkawi, surrounded by lush greenery and natural rocks formations. This 14-tier waterfall tumbles down Mount Raya, the highest mountain on the island, into a crystal clear lake at the bottom.
3. Kukenan/Cuquenan Falls. Kukenan/Cuquenan Falls (Photo: Wikipedia). This is the second tallest waterfall in Venezuala (next to Angel Falls) and is ranked as one of the highest waterfalls in the world. This plunge waterfall has a single drop of 674 meters and trickles down towards Kukenan Tepui mesa.