medication interactions exist: (1) pharmacokinetic interactions, in which alcohol interferes. with the metabolism of the medication, and (2) pharmacodynamic interactions, in which. alcohol enhances the effects of the medication, particularly in the central nervous system. (e.g., sedation).
It is also known by its drug name, Celecoxib. Celebrex is used to treat pain, stiffness and discomfort caused by lupus in joints and other tissues. Unlike other drugs in its class, Celebrex does not interfere with blood clotting. Celebrex should not be used by people who are allergic to nonsteroidal anti-inflammatory drugs (NSAIDs) such as Aspirin or Ibuprofen.
Selective inhibitors (Celebrex) do not affect platelets. If you already have blood pressure or kidney problems, NSAIDs may worsen kidney function. Fluid retention or further elevation in blood pressure may occur. Reduced kidney function can occur with either Cox-1 or Cox-2 inhibitors. If you have lupus nephritis, you and your doctor should closely supervise your use of NSAIDs to reduce the potential for further harm to your kidneys. Occasionally lupus patients may experience elevations in their liver enzyme blood tests, suggesting a mild liver inflammation (hepatitis). Usually this does not mean that the medication must be stopped, but liver tests should be performed on a regular basis. Worsening of symptoms in people with asthma or inflammatory bowel disease.