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Hemosiderin collects throughout the body in hemochromatosis. Hemosiderin deposition in the liver is a common feature of hemochromatosis and is the cause of liver failure in the disease. Deposition in the pancreas leads to diabetes and in the skin leads to hyperpigmentation.
Hemosiderin is a pigment that is a byproduct of hemoglobin that has spread into the tissues following injury with bleeding and bruising of the tissues. It contains iron pgiment and may take along time (years) for the body to metaoblize the iron and pigment that has spread into the tissues. Otto Joseph Placik, MD.