If antibody binds to normal tissues it can cause damage to the body or create other disease symptoms. Rheumatoid arthritis is a good example of an autoimmune disease. Antibodies that react with body tissues are felt to contribute to joint swelling and pain.
In eukaryotic cells the pyruvate decarboxylation occurs inside the mitochondria, after transport of the substrate, pyruvate, from the cytosol. The transport of pyruvate into the mitochondria is via a transport protein and is active, consuming energy. Passive diffusion of pyruvate into the mitochondria is impossible because it is a polar molecule. On entry to the mitochondria the pyruvate decarboxylation occurs, producing acetyl CoA.
Making the world better, one answer at a time. In eukaryotic cells, in the cytoplasm and in the mitochondria. A small amount (2 ATP molecules per molecule of glucose) is formed in the cytoplasm.The process is called glycolysis, and does not require oxygen. If oxygen is available, pyruvate formed during glycolysis enters the mitochondria and is there oxidized to carbon dioxide and water.The yield of ATP varies, but is probably a little below 30 molecules of ATP per glucose molecule.aking the world better, one answer at a time. In eukaryotic cells, in the cytoplasm and in the mitochondria. A small amount (2 ATP molecules per molecule of glucose) is formed in the cytoplasm.