The rate for the last 1/3 of the taper should be reduced to  of that for the first 2/3. Clonazepam is one of the nitro-benzodiazepines series, i.e. nitrazepam, flunitrazepam, clonazepam, and nimetazepam. It has a half-life of 20-50 hours and accumulates from 1.5 to 3 times the daily dose level.
Noun. 1. myeloma-a tumor of the bone marrow (usually malignant) composed of cells normally found in bone marrow. malignant neoplasm, malignant tumor, metastatic tumor-a tumor that is malignant and tends to spread to other parts of the body.
Multiple myeloma is a cancer that affects a type of white blood cell called a plasma cell. Plasma cells produce antibodies to help fight infection and disease. In multiple myeloma, cancerous plasma cells (myeloma cells) are found in the bone marrow, the spongy tissue inside bones that manufactures blood cells.When myeloma cells accumulate in the bones, they can crowd out normal cells and invade bone tissue, damaging and weakening bones.ommon symptoms of multiple myeloma include bone pain in the back and ribs; broken bones, usually in the spine; feeling weak or tired; excessive thirst; frequent infections and fevers; weight loss; nausea or constipation; and frequent urination.