In turn, its influence on the reward circuit can lead a user to bypass survival activities and repeat drug use. Chronic cocaine use can lead to a cocaine addiction and in some cases damage the brain and other organs. An addict will continue to use cocaine even when faced with adverse consequences.
vasodilator (vÄÂ´zÅdÄ«Â´lÄtur), n 1. an agent that causes dilation of the blood vessels. n 2. a drug that relaxes the smooth muscle walls of the blood vessels and increases their diameter.
From Wikipedia, the free encyclopedia. Vasodilation (or vasodilatation) refers to the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles.asodilation directly affects the relationship between mean arterial pressure, cardiac output, and total peripheral resistance (TPR). Vasodilation occurs in the time phase of cardiac systole, whereas vasoconstriction follows in the opposite time phase of cardiac diastole.