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The origin of replication (also called the replication origin) is a particular sequence in a genome at which replication is initiated.This can either involve the replication of DNA in living organisms such as prokaryotes and eukaryotes, or that of DNA or RNA in viruses, such as double-stranded RNA viruses.he origin of replication (also called the replication origin) is a particular sequence in a genome at which replication is initiated. This can either involve the replication of DNA in living organisms such as prokaryotes and eukaryotes, or that of DNA or RNA in viruses, such as double-stranded RNA viruses.
DNA Synthesis Begins at Replication Origins. The process of DNA replication is begun by initiator proteins that bind to the DNA. and pry the two strands apart, breaking the hydrogen bonds between the bases. The positions at which the DNA is first opened are called replication origin. They. usually marked by a particular sequence of nucleotides.