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Neutropenia is classified as mild, moderate, or severe, based on the ANC. Mild neutropenia is present when the ANC is 1000-1500 cells/ÂµL, moderate neutropenia is present with an ANC of 500-1000/ÂµL, and severe neutropenia refers to an ANC lower than 500 cells/ÂµL. The risk of bacterial infection is related to both the severity and duration of the neutropenia.
1 You are allergic to cyclophosphamide or any other component in the drug. 2  You have had radiation treatment in the past. 3  Your absolute neutrophil count (ANC) is less than 1,500.  Your platelet count (PLT) is less than 50,000.