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slide 2 of 4. Causes of Lipomas One common cause of lipomas is genetic. A patient may have several close relatives with histories of fatty tumors. Also, minor injuries may cause lipomas to develop, so it is important to monitor your body when you experience an injury.
Lipomas are soft, fatty lumps that grow under the skin. They're harmless and can usually be left alone if they're small and painless. Lipomas are non-cancerous (benign) and are caused by an overgrowth of fat cells.They can grow anywhere in the body where there are fat cells, but are usually seen on the:1  shoulders.ipomas are soft, fatty lumps that grow under the skin. They're harmless and can usually be left alone if they're small and painless. Lipomas are non-cancerous (benign) and are caused by an overgrowth of fat cells. They can grow anywhere in the body where there are fat cells, but are usually seen on the: 1  shoulders.