The following are additional Purdue OWL resources to help you write your cover letter: 1  Cover Letter Workshop- Formatting and Organization. 2  Example Employment Documents. 3  Cover Letters 1: Quick Tips. 4  Cover Letters 2: Preparing to Write a Cover Letter. 5  Cover Letter Presentation. 6  Job Search Documents for Working Class Positions.
1 IgG deficiency with hyper-IgM is a disease that results when the B-cell fails to switch from making IgM to IgG. 2  This produces an increase in the amount of IgM antibodies present and a decrease in the amount of IgG antibodies. 3  This disease is the result of a genetic mutation.
Signs and symptoms. Infections that commonly affect people with IgG deficiency include: Sinus infections and other respiratory infections. Ear infections. Pneumonia.Bronchitis. Infections that result in sore throat. blood test that measures immunoglobulin can show abnormally low levels of the antibodies and diagnose IgG deficiency. It's possible to have a normal level of total IgG, so the testing of the IgG subclasses is important.