1 Dagobert II, 679; he was one of the last kings of the Merovingian line, murdered by persons unknown in the Ardennes Forest on December 23.  Giovanni Borgia, 2nd Duke of Gandia, 1497; his body was recovered in the Tiber with his throat slit and about nine stab wounds on his torso.
Bottlenecks and Founder Effects. Genetic drift can cause big losses of genetic variation for small populations. Population bottlenecks occur when a populations size is reduced for at least one generation.ottlenecks and Founder Effects. Genetic drift can cause big losses of genetic variation for small populations. Population bottlenecks occur when a populations size is reduced for at least one generation.
After a few generations, the population may look very different from the original population. In rare cases, a bottleneck may even lead to speciation. This article has a great comparison between the Founder's effect and Genetic Drift. Here is an article relating Genetic Drift and Effective population size.