In biology, the active site is the region of an enzyme where substrate molecules bind and undergo a chemical reaction. The active site consists of residues that form temporary bonds with the substrate (binding site) and residues that catalyse a reaction of that substrate (catalytic site).
Seattle is rolling out 11 rainbow crosswalks in Capitol Hill this week, adding a colorful bang to the annual Pride celebration. The crosswalks cost the city $66,000, said Seattle Department of Transportation spokesman Rick Sheridan, and are permanent.
[edit]. Many people drive to the border, park on the US side, and walk across. There are many lots available for this, which charge $4-$9 a day. While there are many taxis waiting to take you across, it's only about a five minute walk; follow the signs across.