In biology, the active site is the region of an enzyme where substrate molecules bind and undergo a chemical reaction. The active site consists of residues that form temporary bonds with the substrate (binding site) and residues that catalyse a reaction of that substrate (catalytic site).
Seattle is rolling out 11 rainbow crosswalks in Capitol Hill this week, adding a colorful bang to the annual Pride celebration. The crosswalks cost the city $66,000, said Seattle Department of Transportation spokesman Rick Sheridan, and are permanent.
The idea to create rainbow crosswalks appears to have first emerged in West Hollywood as part of the 2012 Gay Pride Month celebrations, initially proposed by the LA based artist Martin Duvander with the crosswalks at the intersection of San Vicente Boulevard and Santa Monica Boulevard painted rainbow colors for the month of June.