One common cause of SLUDGE is exposure to organophosphorus insecticides (including parathion, malathion, and diazinon) or nerve gas, such as sarin. These agents phosphorylate acetylcholinesterase, thereby irreversibly deactivating acetylcholinesterase and raising acetylcholine levels and causing SLUDGE.
Every stone grants different abilities to its owner. The Infinity Gems (previously known as Soul Gems) are some of the most powerful artifacts in the Universe. Each one allows its owner complete omnipotence over one aspect of the universe: time, space, reality, mind, power, and soul. When all six are directly wielded together, nothing is impossible for their bearer.
Loki eventually won the wager by using the Reality Gem and was granted the seventh gem, which was linked to the Eternal Sersi. When she came into contact with Loki the two of them merge together reuniting all the gems and recreating Nemesis.