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slide 2 of 4. Causes of Lipomas One common cause of lipomas is genetic. A patient may have several close relatives with histories of fatty tumors. Also, minor injuries may cause lipomas to develop, so it is important to monitor your body when you experience an injury.
Image Source: rheumatologynetwork.com. 1  Spinal neoplasms or tumors: The can cause spinal cord compression that impinges on the thecal sac and crowds the. 2  caudal nerve roots, resulting to cauda equina syndrome [ 2 3  ]. Epidural lipomatosis: This refers to the abnormal build-up of epidural fat.he thecal sac is a covering of the spinal canal that is filled with cerebrospinal fluid (CSF). It houses the spinal cord and nerve roots. It is made up of outer arachnoid membrane and inner dura. It is wider in females. The length is approximately until S1 to S3 vertebral levels.