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Then there were the scary side effects. Though rare, some of Neulastaâs serious side effects include acute respiratory distress syndrome (ARDS), severe allergic reactions and fatal splenic rupture. The scariest one for me, however, was the more commonly reported reaction: bone pain.
Some of these side effects can be managed with palliative therapy, but others may require dose adjustments, temporary or permanent discontinuation of treatment. Rash: Nevirapine commonly causes a skin rash, though in some patients it can cause hepatitis and a life-threatening hypersensitivity reaction (see below).In developed countries, about 17% of the patients appear to develop a rash on nevirapine. The rash can be severe leading about 6-8% of patients to stop treatment.f treatment is interrupted for more than a week, restart with the lead-in dosing protocol (with one 200mg nevirapine tablet daily for the first 14 days in combination with AZT/3TC). If treatment was interrupted because of nevirapine-related side effects, watch for any signs of toxicity during lead-in treatment.