Providers may obtain provider enrollment forms by contacting the Out-of-State Provider Unit at (916) 636-1960 for forms to be mailed or by downloading the appropriate forms from the Medi-Cal website's Provider Enrollment webpage.
Humans carry one to two lethal recessive mutations on average, study estimates Posted on April 8, 2015 by Kevin Jiang Humans carry on average one to two mutations that, if inherited from both parents, can cause severe genetic disorders or death before reaching reproductive age, report scientists from the University of Chicago and Columbia University.
Previous work had suggested a human mutation rate around 2.5 x 10 -8 per site per generation. The new study found less than half the expected number of mutations between these parents and offspring, an estimated rate of only 1.1 x 10 -8 per site. divergence date of 6 million years gave rise to a human per-site mutation rate of 0.65 x 10 -9 per year (1.3 x 10 -8 per 20-year generation). A divergence date of 7 million years lowered the mutation rate to 0.57 x 10 -9 per year. Low mutation rates do not always result from these studies.