One common cause of SLUDGE is exposure to organophosphorus insecticides (including parathion, malathion, and diazinon) or nerve gas, such as sarin. These agents phosphorylate acetylcholinesterase, thereby irreversibly deactivating acetylcholinesterase and raising acetylcholine levels and causing SLUDGE.
Every stone grants different abilities to its owner. The Infinity Gems (previously known as Soul Gems) are some of the most powerful artifacts in the Universe. Each one allows its owner complete omnipotence over one aspect of the universe: time, space, reality, mind, power, and soul. When all six are directly wielded together, nothing is impossible for their bearer.
Additionally, magic anomalies drop black soul gems filled with grand souls. They are also available for purchase from Enthir, a mage of the College of Winterhold, as well as from Falion in Morthal. Each gem is priced at about 1300 . Black soul gems can also be obtained by mining geode veins, found only in Blackreach.