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Researchers say consumption of artificial sweeteners such as saccharin, sucralose and aspartame led to increased risk of glucose intolerance, a condition linked to diabetes. Sweet âN Low contains saccharin. Equal original contains aspartame. Splenda contains sucralose.
One concern about artificial sweeteners is that they affect the bodyâs ability to gauge how many calories are being consumed. Some studies show that sugar and artificial sweeteners affect the brain in different ways. The human brain responds to sweetness with signals to eat more.