Merbau (pronounced MER-boo), also known as kwila or ipil, is a tropical timber which inhabits mangrove forests. The wood is naturally oily with a high tannin content, making it highly durable and resistant to weathering, decay and termites.Its appearance is a deep reddish brown with occasional flecks of yellow which enhance its visual appeal.he wood is naturally oily with a high tannin content, making it highly durable and resistant to weathering, decay and termites. Its appearance is a deep reddish brown with occasional flecks of yellow which enhance its visual appeal.
Mechanism Of Action. The exact mechanism of action of NORTHERA in the treatment of neurogenic orthostatic hypotension is unknown. NORTHERA is a synthetic amino acid analog that is directly metabolized to norepinephrine by dopadecarboxylase, which is extensively distributed throughout the body.
Clinical studies (described below) examined the efficacy of NORTHERA in the short-term (1 to 2 weeks) and over longer-term periods (8 weeks; 3 months). Studies 301 and 306B showed a treatment effect of NORTHERA at Week 1, but none of the studies demonstrated continued efficacy beyond 2 weeks of treatment.