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Mayonnaise is a popular treatment for getting rid of head lice. It is affordable and safe. However, mayonnaise does not remove nits, the eggs laid by head lice. If you use mayonnaise to kill head lice, you will have to use another method, such as combing with a fine-toothed comb, to remove nits.
If it doesn't work, get out the mayo, and rub the  mayo thoroughly in all of the places on your scalp.  Rub extra behind the ears and at the neck because lice like warm  places. After rubbing mayo, leave it in several hours, then comb  out the eggs. Rinse hair thoroughly with warm water, then wash.   Note: You MUST wash all bedding, hats, etc. at the same time. Use  the hottest water possible given the type of fabric. Dry in the  dryer on the hottest setting, depending on type of fabric.