Patients with renal failure, usually end-stage renal disease (ESRD), commonly are afflicted by severe pruritus. The pathogenesis of ESRD pruritus is unknown, but improving the quality of dialysis can reduce the prevalence and severity of ESRD pruritus.
The earlier generation of Buick Park Avenue ran from 1991 through 1996, with substantial updates for the 1994 model year. It shared its underpinnings with the Oldsmobile 98, that make's largest sedan, as well as a number of Cadillac front-wheel-drive sedans.
The North American version of the Mokka was unveiled as the Buick Encore at Detroit's 2012 North American International Auto Show and officially went on sale for the 2013 model year in January 2013. It is Buick's first subcompact crossover SUV and is available in front or all-wheel drive.