Patients with renal failure, usually end-stage renal disease (ESRD), commonly are afflicted by severe pruritus. The pathogenesis of ESRD pruritus is unknown, but improving the quality of dialysis can reduce the prevalence and severity of ESRD pruritus.
The earlier generation of Buick Park Avenue ran from 1991 through 1996, with substantial updates for the 1994 model year. It shared its underpinnings with the Oldsmobile 98, that make's largest sedan, as well as a number of Cadillac front-wheel-drive sedans.
After a series of 3,000 Park Avenue Special Edition models in 2005--300 of which had a subtle black-on-platinum two-tone paint job--both the Park Avenue and the slightly smaller Buick LeSabre were replaced by the 2006 Buick Lucerne, which shared components with the Cadillac DTS, new the same year.