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Polar molecules are hydrophylic. Because the inner portion of the phospholipid bilayer (plasma membrane) consists of hydrophobic interactions, generally polar molecules cannotâ¦ pass directly though. These molecules require protein channels to actively or passively move between the cytosol and the plasma membrane.
plasma membranes on human cells mainly consist of a phospholipid bilayer, this simply means its layered. The top outer layer contains hydrophilic heads that are polar and so are soluble in water. These are the parts that contain the phosphor atom. Then there is a hydrophobic layer made of fatty acid tales. This means no water soluble molecules can pass through it but lipid soluble molecules can.