A Baker's cyst is a swelling in the space behind the knee. Baker's cysts most commonly affect women over the age of 40. Symptoms of a Baker's cyst include joint locking, knee, and calf pain. Baker's cyst often resolves without medication.
The phosphatidylethanolamine N-methyltransferase (PEMT) 5465GâA (rs7946) genotype interacted (Pâ©½0.007) with the plasma betaine to choline ratio to modulate indicators of metabolic stress with stronger inverse associations observed among overweight men with the PEMT 5465GG genotype.
An individualâs genotype includes their full hereditary information, even if it is not expressed. This information is determined by the genes passed on by the parents at conception. An individualâs phenotype only includes expressed genes.