ESTRING (estradiol vaginal ring) PLACEMENT. The exact position of ESTRING (estradiol vaginal ring) is not critical, as long as it is placed in the upper third of the vagina. When ESTRING (estradiol vaginal ring) is in place, you should not feel anything.he soft, flexible ring is placed in the upper third of the vagina (by the physician or the patient). ESTRING (estradiol vaginal ring) should be removed after90 days of continuous use. If continuation of therapy is indicated, the flexible ring should be replaced.
Fertilization takes place in the fallopian tube, more specifically the juncture of the ampulla and isthmus (ampullary-isthmic junction). The ovaries will ovulate and expel a mature ovum due to a surge in the Leutenizing Hormone.
(biology) Fertilization may be internal, when it occurs within the female body, or external, when it occurs outside. The process includes plasmogamy (the union of the cytoplasm of the gametes) followed by karyogamy (the union of the nuclei of two gametes).