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Cleft lip and palate is due to tissues of the face not properly joining together during development. They are a type of birth defect. The cause in most cases is unknown. Risk factors include smoking during pregnancy, diabetes, an older mother, obesity, and certain medications such as some used to treat seizures.
Although I do believe it can be hereditary....I think a lot of these different anomalies/deformities are just the luck of the draw! It can also not be hereditary, u can get it from the mom taking drugs and other substances. I am a 52 year old male who was born with a unilateral cleft lip and palate.