SNAREs are integral membrane proteins (v-SNAREs on vesicles, t-SNAREs on the target organelles) and are thought to provide specificity to the fusion process1â5. It has been suggested that Sec17p and SeclSp bind to v-SNARE/t-SNARE complexes and mediate the membrane fusion event1â3.
In 2015, 4,976 people died in motorcycle crashes, up 8.3 percent from 4,594 in 2014, according to the National Highway Traffic Safety Administration (NHTSA). In 2014, motorcyclists were 27 times more likely than passenger car occupants to die in a crash per vehicle mile traveled, and almost five times more likely to be injured.
1 Alcohol related fatalities account for 39% of all traffic fatalities. 2  The average BAC among fatally injured drunk drivers is .16%, or twice the legal limit.  The risk of death for drivers in single vehicle crashes with an elevated blood alcohol concentration is 385 times that of a zero BAC driver.