A Baker's cyst is a swelling in the space behind the knee. Baker's cysts most commonly affect women over the age of 40. Symptoms of a Baker's cyst include joint locking, knee, and calf pain. Baker's cyst often resolves without medication.
The phosphatidylethanolamine N-methyltransferase (PEMT) 5465GâA (rs7946) genotype interacted (Pâ©½0.007) with the plasma betaine to choline ratio to modulate indicators of metabolic stress with stronger inverse associations observed among overweight men with the PEMT 5465GG genotype.
A gene is a locus (or region) of DNA which is made up of nucleotides and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be.