If youâre using B vitamins to help prevent hot flashes, be sure to use the form of niacin called niacinamide. Other forms of niacin dilate the blood vessels, which can cause flushing and worsen hot flashes, rather than relieve them. Folic acid helps the body manufacture and use estrogen.
Soliris wins the prize as the most expensive drug in the United States. Unlike many of the drugs on this list, at least Soliris can claim to be a very effective drug, treating paroxysmal nocturnal hemoglobinuria, a disorder affecting about 8,000 Americans.
The yearly cost per patient of as much as $700,000 is even more than the manufacturer, Alexion Pharmaceutical, charges in the United States, which typically has the steepest prices globally, says the Patented Medicines Price Review Board (PMPRB).