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Latanoprost was the first prostaglandin to be approved as first-line treatment for elevated eye pressure. Three newer prostaglandins are travoprost (Travatan), bimatoprost (Lumigan),and tafluprost (Zioptan). These drugs are used to reduce eye pressure in patients with open-angle glaucoma and high ocular pressure. Side effects include itching, redness, and burning during administration. Muscle and joint pain may also occur.
Combigan treats glaucoma and high blood pressure in the eye. Allow at least 5 minutes between administering Combigan and any other eye drop products. Combigan Overview. Combigan is a prescription medication used to reduce elevated pressure in patients with glaucoma or ocular hypertension (higher than normal blood pressure inside the eye). It is a single product containing two medications: brimonidine and timolol. Brimonidine belongs to a group of drugs called alpha-adrenergic agonists.