A Baker's cyst is a swelling in the space behind the knee. Baker's cysts most commonly affect women over the age of 40. Symptoms of a Baker's cyst include joint locking, knee, and calf pain. Baker's cyst often resolves without medication.
The phosphatidylethanolamine N-methyltransferase (PEMT) 5465GâA (rs7946) genotype interacted (Pâ©½0.007) with the plasma betaine to choline ratio to modulate indicators of metabolic stress with stronger inverse associations observed among overweight men with the PEMT 5465GG genotype.
It may seem that anything dependent on the genotype is a phenotype, including molecules such as RNA and proteins. Most molecules and structures coded by the genetic material are not visible in the appearance of an organism, yet they are observable (for example by Western blotting) and are thus part of the phenotype.