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Skin, mouth, genital symptoms â One characteristic feature of acute HIV infection is open sores or ulcers. These sores or ulcers can develop in the mouth, the esophagus (the tube that extends from the mouth to the stomach), the anus, or the penis. The ulcers are usually painful.
Common symptoms that occur in approximately 50 percent or more of people with acute HIV syndrome include: 1  Fever (100.4 to 104 F), possibly with night sweats, in at least 80 percent of people; 2  Swollen, sore âglandsâ (i.e., lymph nodes); 3  Achy joints and/or muscles;  Rash, especially on your upper body, neck and/or face;