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Skin, mouth, genital symptoms â One characteristic feature of acute HIV infection is open sores or ulcers. These sores or ulcers can develop in the mouth, the esophagus (the tube that extends from the mouth to the stomach), the anus, or the penis. The ulcers are usually painful.
If you have HIV and you are not on ART, eventually the virus will weaken your bodyâs immune system and you will progress to AIDS (acquired immunodeficiency syndrome), the late stage of HIV infection. Symptoms can include: 1  Rapid weight loss. 2  Recurring fever or profuse night sweats. 3  Extreme and unexplained tiredness. 4  Prolonged swelling of the lymph glands in the armpits, groin, or neck. 5  Diarrhea that lasts for more than a week. 6  Sores of the mouth, anus, or genitals. 7  Pneumonia.