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2. in oncology, the change that a normal cell undergoes as it becomes malignant. bacterial transformation the exchange of genetic material between strains of bacteria by the transfer of a fragment of naked DNA from a donor cell to a recipient cell, followed by recombination in the recipient chromosome. (trÄnsâ²fÉr-mÄâ²shÉn).
DNA can be exchanged among bacteria by three methods: transformation, transduction and conjugation. Transformation is one of the most popular techniques of molecular genetics because it is often the best way to reintroduce experimentally altered DNA into cells. This technique was first discovered in bacteria, but other ways have been designed to transform many types of animal and plant cell as well.