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As Aching pointed out the beep test or shuttle test uses an estimated VO2 max value. This relationship between shuttle level and VO2 max test has backed up by many studies over many years. It is a test where athletes who are used to change of speed and direction will perform best due to the specific demands of the test.
The BNP test is a heart failure blood test. It measures the level of a hormone in your blood called B-type Natriuretic Peptide. Your heart's pumping chambers - the ventricles - produce extra BNP when they can't pump enough blood to meet your body's needs. So if your BNP level is high, you probably have heart failure.