The field is familiar with the five conditions of collective impact, but what are the... Update: The Spanish-language version of this article, Encauzamiento del cambio: cÃ³mo lograr que el impacto colectivo funcione, is now added to this page for download.
The tetanus toxin affects the site of interaction between the nerve and the muscle that it stimulates.This region is called the neuromuscular junction.The tetanus toxin amplifies the chemical signal from the nerve to the muscle, which causes the muscles to tighten up in a continuous (tetanic or tonic) contraction or spasm.This results in either localized or generalized muscle spasms.he tetanus toxin amplifies the chemical signal from the nerve to the muscle, which causes the muscles to tighten up in a continuous (tetanic or tonic) contraction or spasm. This results in either localized or generalized muscle spasms.
Local tetanus manifests with muscle spasms at or near the wound that has been infected with the bacteria. Cephalic tetanus primarily affects one or several muscles in the face rapidly (in one to two days) after a head injury or ear infection. Trismus (lockjaw) may occur. The disease can easily progress to generalized tetanus. Neonatal tetanus is similar to generalized tetanus except that it affects a baby that is less than 1 month old (called a neonate).