Several reports demonstrate unexplained consequences of mutations on the expression of the different dystrophin isoforms and their balance. The most prominent example is found in some cases of X-linked dilated cardiomyopathy (XLDC).
In particular, calcitonin has the ability to decrease blood calcium levels at least in part by effects on two well-studied target organs: 1  Bone: Calcitonin suppresses resorption of bone by inhibiting the activity of osteoclasts, a cell type that digests bone matrix, releasing calcium and phosphorus into blood.
Yes, but in a totally different context. Because it inhibits bone breakdown (resorption) when given in very large doses, calcitonin is sometimes given as a drug to people who have osteoporosis. It helps maintain bone density and has a pain-relieving effect on bone. The supplement is usually administered as an injection or nasal spray.