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30 E653 (Morphine sulfate SR 30 mg). Pill imprint 30 E653 has been identified as Morphine sulfate SR 30 mg. Morphine is used in the treatment of chronic pain; pain and belongs to the drug class narcotic analgesics.
Step 1. Calculate the 24 hr morphine dose: 3 mg x 24 = 72 mg IV morphine/24 hrs; Step 2. Convert IV to oral morphine: at a ratio of 1 mg IV = 3 mg oral; thus 72 mg IV = 216 mg po/24 hours; Step 3. Convert the oral morphine dose to Duragesic - there are two methods: METHOD 1. Look in the PDR, find the morphine conversion table, it says that 135-224 mg of morphine = 50 mcg patch. Note, this range of morphine is very broad; 50% of patients will be under-dosed when this conversion table is used. METHOD 2. Use a ratio of MS:fentanyl of 100:1; 216mg/100/24hrs = 90 mcg/hr, can rounded to 75 mcg or 100 mcg patch.