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Short-Term Effects of Heroin. Often injected, the immediate effects of heroin are to modulate pain perception. As a street drug, dosing is impossible to fully control, and the side effects of decreased heart rate and breathing pose immense risk to users.
Long Term Effects. The most common long-term effect of abusing OxyContinÂ®, and perhaps the worst effect, is the addiction itself. Addiction ruins a personâs life bit by bit, becoming worse over time. In this way, OxyContinÂ® abuse is no different from heroin, cocaine, or alcohol abuse.ong-term physical effects of OxyContinÂ® abuse, or any opioid drug abuse, include: Painful Withdrawal that Maintains Addiction. 1  Restlessness. 2  Muscle and bone pain. 3  Muscle spasms. 4  Insomnia. 5  Diarrhea and vomiting. 6  Chills and goose bumps. 7  Intense anxiety.