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What Can I Do if my HDL Cholesterol Level Is Low? If your HDL is low, you can take several steps to boost your HDL level and reduce your heart disease risk: Exercise. Aerobic exercise for 30 to 60 minutes on most days of the week can help pump up HDL. Quit smoking. Tobacco smoke lowers HDL, and quitting can increase HDL levels. Keep a healthy weight.
Fibrates are mostly effective at lowering triglycerides and in heightening HDL levels, according to NHLBI. These drugs usually lower LDL by 10 to 20 percent, Eckel says. For those who take this type of medication, HDL increases are usually in the neighborhood of a modest 10 to 15 percent.