A Baker's cyst is a swelling in the space behind the knee. Baker's cysts most commonly affect women over the age of 40. Symptoms of a Baker's cyst include joint locking, knee, and calf pain. Baker's cyst often resolves without medication.
The phosphatidylethanolamine N-methyltransferase (PEMT) 5465GâA (rs7946) genotype interacted (Pâ©½0.007) with the plasma betaine to choline ratio to modulate indicators of metabolic stress with stronger inverse associations observed among overweight men with the PEMT 5465GG genotype.
The genotype â a term coined by Danish botanist, plant physiologist and geneticist Wilhelm Johannsen in 1903 â is the part (DNA sequence) of the genetic makeup of a cell, and therefore of an organism or individual, which determines a specific characteristic (phenotype) of that cell/organism/individual.