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[edit on Wikidata] Cardiorenal syndrome (CRS) is an umbrella term used in the medical field that defines disorders of the heart and kidneys whereby âacute or chronic dysfunction in one organ may induce acute or chronic dysfunction of the otherâ.
Chronic renal failure (CRF) or kidney failure is the progressive loss of kidney function. The kidneys attempt to compensate for renal damage by hyperfiltration (excessive straining of the blood) within the remaining functional nephrons (filtering units that consist of a glomerulus and corresponding tubule). Over time, hyperfiltration causes further loss of function.