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The proximal tubules make up a significant portion of the kidneys; proximal tubule epithelial cells are the most populous cell type in the kidney, and carry out diverse regulatory and endocrine functions where numerous transporters are located.he proximal tubules make up a significant portion of the kidneys; proximal tubule epithelial cells are the most populous cell type in the kidney, and carry out diverse regulatory and endocrine functions where numerous transporters are located.
Proximal vs Distal Convoluted Tubule. Human kidneys are important organs located in the lower back and are responsible for many crucial functions including filtration, reabsorption and secretion. These functions basically carryout by a small unit called nephron; the functional and structural unit of the kidney.