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Grierson-Gopalan syndrome (better known as burning feet syndrome). Consists of severe burning and aching of the feet, hyperaesthesia, pain, elevated skin temperature, and vasomotor changes of the feet, associated with excessive sweating and general body wasting. Ocular complications may include scotoma and amblyopia. Prevalent in women; onset between 20 and 40 years of age.
Uhthoff's phenomenon is the worsening of neurologic symptoms in multiple sclerosis and other neurological, demyelinating conditions when the body gets overheated from hot weather, exercise, fever, or saunas and hot tubs. It is possibly due to the effect of increased temperature on nerve conduction. With an increased body temperature, nerve impulses are either blocked or slowed down in a damaged nerve but once the body temperature is normalized, signs and symptoms may disappear or improve.