Mitochondria under the microscope. Microscopes have been crucial for our understanding of mitochondrial structure and function. Mitochondria are visible under the light microscope although little detail can be seen.Transmission electron microscopy (left) shows the complex internal membrane structure of mitochondria, and electron tomography (right) gives a three-dimensional view.itochondria under the microscope. Microscopes have been crucial for our understanding of mitochondrial structure and function. Mitochondria are visible under the light microscope although little detail can be seen.
Splenomegaly: Abnormal enlargement of the spleen. Splenomegaly is a sign of an underlying condition, such as severe liver disease, leukemia, or mononucleosis. Patients with splenomegaly should avoid activities that risk trauma to the abdomen, including contact sports, because of risk of bleeding from the injured spleen.
Causes of splenomegaly include: 1  Myeloproliferative diseases such as chronic lymphocytic leukemia, chronic myelogenous leukemia, large granular cell leukemia, polycythemia vera. 2  Lymphoproliferative diseases such as lymphoma especially of the hairy cell variety. 3  Lipid storage disorders such as Gaucherâs or Niemann-Pick disease.