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However, sadness, depression, grief, or anxiety are a common cause of weight loss that is not explained by other factors, especially among the elderly. Cancer may also cause decreased appetite. You may lose weight without trying. Cancers that may cause you to lose your appetite include: 1  Colon cancer. 2  Ovarian cancer. 3  Stomach cancer. 4  Pancreatic cancer.
Loss of appetite is a loss of the desire to eat. Not eating can lead to weight loss. Weight loss can cause weakness and fatigue, which affect your ability to perform normal activities.Proper nutrition also helps your body prevent and fight infection. Weight loss or lack of appetite may be due to the cancer or sometimes to treatments for the cancer.ot eating can lead to weight loss. Weight loss can cause weakness and fatigue, which affect your ability to perform normal activities. Proper nutrition also helps your body prevent and fight infection. Weight loss or lack of appetite may be due to the cancer or sometimes to treatments for the cancer.