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Mission, Texas. Mission is a city in Hidalgo County, Texas. The population was 80,452 in 2012. Mission is part of the McAllenâEdinburgâMission and ReynosaâMcAllen metropolitan areas.
In 1684, a second mission in the area of San Angelo existed from March to May. Its location was near the juncture of the Colorado (San Clemente) River and the Concho River of Texas (then called the Nueces), most sources say. Others have placed the mission farther east, on the South Llano River and the San Saba River.