Nicotinic receptor activation causes the opening of the channel formed by the receptor. This increases the Na+ movement into the target cell, leading to depolarization and generation of the action potential. This rapidly developing change, termed a fast EPSP, is illustrated in Figures 4.3, and 6.2.
Just like red pepper, black pepper has a thermogenic effect when ingested. The spice stimulates your metabolism and thus temporarily increases body heat. A higher basal metabolic rate means higher energy expenditure or more calories burned.
Many people enjoy the spicy flavor of hot peppers, but eating them may trigger indigestion. Indigestion, also known as dyspepsia, can cause stomach upset or an uncomfortable feeling of fullness. Your physician may recommend antacids to relieve pain, but avoiding the consumption of hot peppers also helps you keep indigestion from occurring.