Nicotinic receptor activation causes the opening of the channel formed by the receptor. This increases the Na+ movement into the target cell, leading to depolarization and generation of the action potential. This rapidly developing change, termed a fast EPSP, is illustrated in Figures 4.3, and 6.2.
Just like red pepper, black pepper has a thermogenic effect when ingested. The spice stimulates your metabolism and thus temporarily increases body heat. A higher basal metabolic rate means higher energy expenditure or more calories burned.
What Happens If You Eat The Worldâs Hottest Pepper? Although chilies are found in many dishes throughout the world, capsaicin is actually a neurotoxin and in large enough concentrations can cause seizures, heart attacks, and even death.