Patients with renal failure, usually end-stage renal disease (ESRD), commonly are afflicted by severe pruritus. The pathogenesis of ESRD pruritus is unknown, but improving the quality of dialysis can reduce the prevalence and severity of ESRD pruritus.
The earlier generation of Buick Park Avenue ran from 1991 through 1996, with substantial updates for the 1994 model year. It shared its underpinnings with the Oldsmobile 98, that make's largest sedan, as well as a number of Cadillac front-wheel-drive sedans.
William Durant creates General Motors. On September 16, 1908, Buick Motor Company head William Crapo Durant spends $2,000 to incorporate General Motors in New Jersey. Durant, a high-school dropout, had made his fortune building horse-drawn carriages, and in fact he hated carsâhe thought they were noisy, smelly, and dangerous.