The field is familiar with the five conditions of collective impact, but what are the... Update: The Spanish-language version of this article, Encauzamiento del cambio: cÃ³mo lograr que el impacto colectivo funcione, is now added to this page for download.
The tetanus toxin affects the site of interaction between the nerve and the muscle that it stimulates.This region is called the neuromuscular junction.The tetanus toxin amplifies the chemical signal from the nerve to the muscle, which causes the muscles to tighten up in a continuous (tetanic or tonic) contraction or spasm.This results in either localized or generalized muscle spasms.he tetanus toxin amplifies the chemical signal from the nerve to the muscle, which causes the muscles to tighten up in a continuous (tetanic or tonic) contraction or spasm. This results in either localized or generalized muscle spasms.
Tetanus is caused by an infection with the bacterium Clostridium tetani, which is commonly found in soil, dust and manure.The bacteria generally enter through a break in the skin such as a cut or puncture wound by a contaminated object.etanus often begins with mild spasms in the jaw muscles âalso known as lockjaw or trismus. The spasms can also affect the facial muscles resulting in an appearance called risus sardonicus. Chest, neck, back, abdominal muscles, and buttocks may be affected. Back muscle spasms often cause arching, called opisthotonos.