An inverse agonist is an agent that binds to the same receptor binding-site as an agonist for that receptor and inhibits the constitutive activity of the receptor. Inverse agonists exert the opposite pharmacological effect of a receptor agonist, not merely an absence of the agonist effect as seen with antagonist.An example is the cannabinoid inverse agonist rimonabant. A co-agonist works with other co-agonists to produce the desired effect together.ull agonists bind (have affinity for) and activate a receptor, producing full efficacy at that receptor. One example of a drug that acts as a full agonist is isoproterenol, which mimics the action of adrenaline at Î² adrenoreceptors.
The Last Supper is the final meal that, in the Gospel accounts, Jesus shared with his Apostles in Jerusalem before his crucifixion.The Last Supper is commemorated by Christians especially on Maundy Thursday.n the Gospel of John, after the departure of Judas from the Last Supper, Jesus tells his remaining eleven disciples that he will be with them for only a short time, then gives them a New Commandment, stating: âA new command I give you: Love one another.
Easter was celebrated at the same time as Passover until 325 A.D (Council of Nicaea), making it effectively an annual last supper event commemorating Passover through crucifixion and resurrection. The reasons for change were on the surface calendar based. Dipping in the bowl ' is referred to in Matthew 26.23 and in Mark 14.20 this is specifically 'dipping the bread'. Jesus' last supper concluded with the singing of hymns (Matthew 26.30; Mark 14.26), possibly the second half of the Hallel (Psalms 113-118) traditionally associated with Passover.