SNAREs are integral membrane proteins (v-SNAREs on vesicles, t-SNAREs on the target organelles) and are thought to provide specificity to the fusion process1â5. It has been suggested that Sec17p and SeclSp bind to v-SNARE/t-SNARE complexes and mediate the membrane fusion event1â3.
In 2015, 4,976 people died in motorcycle crashes, up 8.3 percent from 4,594 in 2014, according to the National Highway Traffic Safety Administration (NHTSA). In 2014, motorcyclists were 27 times more likely than passenger car occupants to die in a crash per vehicle mile traveled, and almost five times more likely to be injured.
1 The average age of bicyclists killed in crashes with motor vehicles continues to increase, climbing to 45 years old in 2014, up from 39 in 2004, 32 in 1998, and 24 in 1988. 2  88 percent of those killed were male.  71 percent of bicyclist fatalities occurred in urban areas.