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Take Synthroid with water only on an empty stomach. Take Synthroid 4 hours before or after. taking iron or calcium supplements, or antacids. Soy, cottonseed meal, walnuts, fiber, and. grapefuit juice can affect the absorption of Synthroid.
Synthroid and chronic cough. I am 52 years old, have been taking Synthroid (0.075) daily for many years, and have developed a progressively worsening cough. The cough is productive and becomes progressively worse in the morning approx. an hour after taking the Synthroid, subsiding in the late afternoon. (I drink approx. 3 cups of coffee in the mornings as well.) I have been tested for asthma and was found to be borderline.