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Take Synthroid with water only on an empty stomach. Take Synthroid 4 hours before or after. taking iron or calcium supplements, or antacids. Soy, cottonseed meal, walnuts, fiber, and. grapefuit juice can affect the absorption of Synthroid.
Best Answer: Generally it takes 6 weeks for your thyroid levels to stabilize. That is because medications such as synthroid are a type of thyroid hormone that your body must convert to another form in order to be used by your body. This process takes 6 weeks.