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Mission, Texas. Mission is a city in Hidalgo County, Texas. The population was 80,452 in 2012. Mission is part of the McAllenâEdinburgâMission and ReynosaâMcAllen metropolitan areas.
Mission San Juan The history of Mission San Juan began in the woods of East Texas. In 1716, Mission San JosÃ© de los Nazonis was established to serve the Nazonis Indians. However, the mission was not successful, and whatever was transportable was moved here. On March 5, 1731, the mission was reestablished on the east bank of the San Antonio River and renamed San Juan Capistrano. Despite the new location, the mission still had to contend with adversity. Epidemics of smallpox, measles, and other European disease swept through the mission, causing much suffering and death among the native inhabitants.