Grahame Hardie, David Carling and Alastair T.R. Sim. The A MP-activated protein kinase is a component of a protein-kinase cascade that. is activated by lipid metabolites, and which has recently been found to regulate. several key enzymes of lipid metabolism.
That said, the key difference between rheumatoid arthritis and osteoarthritis is the cause behind how the joints are affected. Osteoarthritis is a slow and progressive degenerative joint disease, that is, it will slowly develop over years of wear-and-tear on the joints and cartilage.
Arthritis is an umbrella term used to describe inflammation of the joints. However, there are different kinds of arthritis, including rheumatoid arthritis (RA) and osteoarthritis (OA). Although RA and OA both affect the joints, theyâre very different forms of the same broader condition.