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Here are all the possible meanings and translations of the word hamstring. Princeton's WordNet(0.00 / 0 votes)Rate this definition: hamstring, hamstring tendon(verb) one of the tendons at the back of the knee. hamstring(verb) make ineffective or powerless. The teachers were hamstrung by the overly rigid schedules. hamstring(verb) cripple by cutting the hamstring.
0. A hamstring injury is a strain or tear to one or more of the three large muscles at the back of the thigh (or their tendons at the back of the knee).