If you had a pulmonary embolism (a blood clot in your lungs [PE]), in the past and still have shortness of breath, even after at least 3 months of anticoagulants (blood thinners), you could develop CTEPH.
But that seemed harder when Lip started dating rich girl Amanda (Nichole Bloom), and it got even more complicated when Mandy moved away from Chicago with her abusive boyfriend. But the entrance of Helene (Sasha Alexander), Lip's professor-turned-lover may just be the biggest complication of them all.
Joey is upset at his recent dating dry spell. When he can't find a date for New Year's Eve, he volunteers to babysit the girls, which seems to be the final nail in the coffin. Danny and Jesse try to help him by secretly taping him for a video dating service. Despite being upset initially, Joey appreciates the gesture when he meets his dream girl.