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What is PUVA? PUVA or photochemotherapy is a type of ultraviolet radiation treatment (phototherapy) used for severe skin diseases. PUVA is a combination treatment which consists of Psoralens (P) and then exposing the skin to UVA (long wave ultraviolet radiation). It has been available in its present form since 1976.
The combination of psoralen and UVA light that is utilized in PUVA therapy causes skin cells to divide less rapidly. This is an effective treatment for skin disorders such as psoriasis, vitiligo and eczema because part of the pathogenic process of these disorders is an increase in the rate of cell division.UVA therapy may be used to treat psoriasis. PUVA therapy can be used to treat skin conditions like vitiligo. Psoriasis typically appears as scaly, reddish colored patches of skin.