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Take pain medication. Taking an over-the-counter medication is one of the most effective ways to make cramps go away. Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and Tylenol work quickly to take away the pain. You can find them in most drug stores.
Dietary changes, such as eating fresh and healthy food, may help reduce cramps as well. Try eating more: 1  calcium-rich foods, such as dried figs, ricotta cheese, and canned sardines.  foods high in antioxidants, such as berries, tomatoes, and bell pepper.