Inbreeding depression is the reduced biological fitness in a given population as a result of inbreeding, or breeding of related individuals. Population biological fitness refers to an organism's ability to survive and perpetuate its genetic material.
A âmicro entity,â as defined in 35 U.S.C. Â§ 123, is a patent applicant who meets the definition of a âsmall entityâ in addition to: (1) not being named on more than four previously-filed, U.S. non-provisional applications; and (2) not having gross income exceeding three times the median U.S. household income for the preceding calendar year in which the applicable fee is being paid.
Microglia. Microglia are the immune effector cells of the CNS and are present in abundance in the brain parenchyma. They constitute approximately 10-20% of the total population of glial cells in the adult (Vaughan and Peters 1974; Banati 2003). These cells are derived from blood-borne macrophages, which migrate into the CNS during development.