A Baker's cyst is a swelling in the space behind the knee. Baker's cysts most commonly affect women over the age of 40. Symptoms of a Baker's cyst include joint locking, knee, and calf pain. Baker's cyst often resolves without medication.
The phosphatidylethanolamine N-methyltransferase (PEMT) 5465GâA (rs7946) genotype interacted (Pâ©½0.007) with the plasma betaine to choline ratio to modulate indicators of metabolic stress with stronger inverse associations observed among overweight men with the PEMT 5465GG genotype.
The genotype of an organism is the inherited instructions it carries within its genome. This genotype-phenotype distinction was proposed by Wilhelm Johannsen in 1911 to make clear the difference between an organism's heredity and what that heredity produces. The distinction is similar to that proposed by August Weismann, who distinguished between germ plasm (heredity) and somatic cells (the body).