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High TSH - High levels of TSH are typically caused by an underactive thyroid or hypothyroidism. This is typically caused by Hashimoto's thyroiditis. If you are already being treated for a thyroid disorder this can be a sign that you need to increase your medication.
In the absence of sufficient iodine, TSH levels remain elevated, leading to goiter, an enlargement of the thyroid gland that reflects the body's attempt to trap more iodine from the circulation and produce thyroid hormones.