If you had a pulmonary embolism (a blood clot in your lungs [PE]), in the past and still have shortness of breath, even after at least 3 months of anticoagulants (blood thinners), you could develop CTEPH.
But that seemed harder when Lip started dating rich girl Amanda (Nichole Bloom), and it got even more complicated when Mandy moved away from Chicago with her abusive boyfriend. But the entrance of Helene (Sasha Alexander), Lip's professor-turned-lover may just be the biggest complication of them all.
The season mainly focuses on the up's and down's of Fiona Gallagher's new relationship with Jimmy Lishman. Their relationship begins when Fiona has her purse snatched at a nightclub and Steve attempts to retreive it from a mugger. The season also follows Kev and Veronica, the Gallagher's neighbours, as they are forced to become foster parents due to fertility problems. The Gallagher patriarch, Frank meets Sheila Jackson, the mother of Lip's girlfriend Karen and the two become a couple.