The cause of irritable bowel syndrome is unknown. Antibiotic-associated colitis usually occurs in people receiving antibiotics. Inflammatory bowel diseases is a common cause of bowel inflammation and low back pain. There are two major forms: Crohns disease and ulcerative colitis. The causes are unknown. â¢Genetic: There is a high similarity of symptoms among identical twins, particularly with Crohn disease.
An effective dose (ED) in pharmacology is the dose or amount of drug that produces a therapeutic response or desired effect in some fraction of the subjects taking it.D50 [edit]. The median effective dose is the dose that produces a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). It is also sometimes abbreviated as the ED50, meaning effective dose, for 50% of people receiving the drug.
In functional antagonist assays, a dose-response curve measures the effect of the ability of a range of concentrations of antagonists to reverse the activity of an agonist. The potency of an antagonist is usually defined by its EC50 value.