Several reports demonstrate unexplained consequences of mutations on the expression of the different dystrophin isoforms and their balance. The most prominent example is found in some cases of X-linked dilated cardiomyopathy (XLDC).
In particular, calcitonin has the ability to decrease blood calcium levels at least in part by effects on two well-studied target organs: 1  Bone: Calcitonin suppresses resorption of bone by inhibiting the activity of osteoclasts, a cell type that digests bone matrix, releasing calcium and phosphorus into blood.
What is Calcitonin? Calcitonin is a hormone used to treat symptoms of Paget's disease of the bone, hypercalcemia (high levels of calcium in the blood) and postmenopausal osteoporosis (bone weakening). This medicine is often ordered for cancer patients experiencing bone pain due to metastasis. This medication reduces the breakdown of bone.