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How It Works. Leflunomide (Arava) is a disease-modifying antirheumatic drug (DMARD) that is used to treat rheumatoid arthritis. It interferes with the progression of the disease by blocking the production of white blood cells that cause the joint inflammation in rheumatoid arthritis.
The recommended dose of Remicade for the treatment of rheumatoid arthritis is 3 mg/kg as a single dose. This means that the amount of each dose is based on the weight of the patient. Therefore, infusions can be more expensive for heavier persons because more Remicade is used. The initial dose should be followed by additional 3 mg/kg doses two and six weeks after the first dose. Thereafter, the maintenance dose is 3 mg/kg every eight weeks.