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Take pain medication. Taking an over-the-counter medication is one of the most effective ways to make cramps go away. Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and Tylenol work quickly to take away the pain. You can find them in most drug stores.
1 Take a warm or a hot bath to help relax muscle. 2  You can also roll a hot water bottle. 3  Cover the bottle with a towel before using. 4  A deficiency of potassium can result in cramps; therefore step up your intake of potassium rich foods â especially fresh fruits. 2 bananas a day will definitely help to treat cramps.