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2. in oncology, the change that a normal cell undergoes as it becomes malignant. bacterial transformation the exchange of genetic material between strains of bacteria by the transfer of a fragment of naked DNA from a donor cell to a recipient cell, followed by recombination in the recipient chromosome. (trÄnsâ²fÉr-mÄâ²shÉn).
Lecture 7. Genetic Transformation (using bacteria and the pGLO plasmid). Genetic transformation is the process by which an organism acquires and expresses a new gene. 1  Genetic engineering is the directed transfer of a gene, or piece of DNA, into a cell (typically a bacteria).