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carbonic anhydrase an enzyme that catalyzes the decomposition of carbonic acid into carbon dioxide and water, facilitating transfer of carbon dioxide from tissues to blood and from blood to alveolar air.
Zinc's role in carbonic anhydrase is to facilitate the water to create a proton H+ and a nucleophilic hydroxide ion. The nucleophilic water molecules attack the carbonyl group of carbon dioxide to convert it into bicarbonate.