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Acinic cell carcinoma (ACC) is a low-grade malignant salivary neoplasm that constitutes approximately 17% of primary salivary gland malignancies. In the head and neck region, the parotid gland is the predominant site of origin and women are usually more frequently diagnosed than men.
Oral squamous cell carcinoma in the most common intraoral site manifesting as a chronic, indurated ulcer. Oral SCC (OSCC) is particularly common in the developing world, mostly in older males.There is concern about an ongoing increase in younger patients and in women.athophysiology. In oral squamous cell carcinoma (OSCC), modern DNA technology, especially allelic imbalance (loss of heterozygosity) studies, have identified chromosomal changes suggestive of the involvement of tumor suppressor genes (TSGs), particularly in chromosomes 3, 9, 11, and 17.