Several reports demonstrate unexplained consequences of mutations on the expression of the different dystrophin isoforms and their balance. The most prominent example is found in some cases of X-linked dilated cardiomyopathy (XLDC).
In particular, calcitonin has the ability to decrease blood calcium levels at least in part by effects on two well-studied target organs: 1  Bone: Calcitonin suppresses resorption of bone by inhibiting the activity of osteoclasts, a cell type that digests bone matrix, releasing calcium and phosphorus into blood.
Calcitonin is a hormone produced in C cells of the thyroid gland. The thyroid gland is located inside the front of your lower neck. Calcitonin helps control the breakdown and rebuilding of bone. Your health care provider may order a calcitonin test when you have symptoms of medullary cancer of the thyroid or multiple endocrine neoplasia (MEN) syndrome, or a family history of these conditions.