In advance of the Monday release of his book, Steve Jobs: A Biography, Isaacson told the CBS News program  60 Minutes  that Jobs said he initially felt the surgery would be too invasive.
The HandiHaler device is an inhalation device used to inhale the dry powder contained in the SPIRIVA capsule. The dry powder is delivered from the HandiHaler device at flow rates as low as 20 L/min. Under standardized in vitro testing, the HandiHaler device delivers a mean of 10.4 mcg tiotropium when tested at a flow rate of 39 L/min for 3.1 seconds (2L total).
Read the Patient Information and the step-by-step Instructions for Use for SPIRIVA HandiHaler before you use your inhaler. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.PIRIVA RESPIMAT has the same active ingredient as Spiriva Â® HandiHaler Â® (tiotropium bromide inhalation powder), which is the number one branded prescription medication for COPD maintenance in the United States.