In switching from immediate-release to extended-release, same total daily dose of metoprolol should be used In switching between oral and IV dosage forms, equivalent beta-blocking effect is achieved in 2.5:1 (oral-to-IV) ratio Take with or immediately following meals metoprolol tartrate: Take with or immediately after meals
Nucleic acids are polymers of individual nucleotide monomers. Each nucleotide is composed of three parts: a 5-carbon sugar, a phosphate group, and a nitrogenous base. Only two 5-carbon sugars are found in nature: ribose and deoxyribose. Deoxyribose is a ribose derivative in which an oxygen atom is missing from one carbon; the carbon was deoxygenated.
The sugar is the 3' end, and the phosphate is the 5' end of each nucleiotide. The phosphate group attached to the 5' carbon of the sugar on one nucleotide forms an ester bond with the free hydroxyl on the 3' carbon of the next nucleotide.