Theoretically, it is possible that diphenhydramine could affect a woman's milk supply, since the medication can suppress prolactin (a hormone important for breast milk production). However, this is probably not an issue for women who are well-established with breastfeeding.
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pl. prodÂ·iÂ·gies. noun. 1  A person with exceptional talents or powers: a math prodigy. 2  An act or event so extraordinary or rare as to inspire wonder: âThe Spies performed prodigies of activity in clambering over the rooftops and cutting the streamers that fluttered from the chimneysâ (George Orwell).