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Symptoms of primary coccidioidomycosis, in decreasing order of frequency, include fever, cough, chest pain, chills, sputum production, sore throat, and hemoptysis. Physical signs may be absent or limited to scattered rales with or without areas of dullness to percussion over lung fields.
Human coccidiosis is produced by species of Isospora; in its severe form it is characterized by diarrhea (sometimes alternating with constipation), fever, abdominal pain, nausea, headache, loss of appetite, and loss of weight.