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Acute limb ischemia is a sudden decrease in limb perfusion that threatens limb viability and requires urgent evaluation and management. Causes of acute limb ischemia include acute thrombosis of a limb artery or bypass graft, embolism from the heart or a diseased artery, dissection, and trauma.
The most prominent features of critical limb ischemia (CLI) are called ischemic rest pain â severe pain in the legs and feet while a person is not moving, or non-healing sores on the feet or legs. 1  Pain or numbness in the feet.  Shiny, smooth, dry skin of the legs or feet.