Patients with renal failure, usually end-stage renal disease (ESRD), commonly are afflicted by severe pruritus. The pathogenesis of ESRD pruritus is unknown, but improving the quality of dialysis can reduce the prevalence and severity of ESRD pruritus.
The earlier generation of Buick Park Avenue ran from 1991 through 1996, with substantial updates for the 1994 model year. It shared its underpinnings with the Oldsmobile 98, that make's largest sedan, as well as a number of Cadillac front-wheel-drive sedans.
The first-generation Buick Enclave three-row utility vehicle has served the entry-luxury brand impressively well over its 10 model years in production. But it has become an ancient thing, and with utility vehicles comprising the majority of Buickâs current sales, the fully redesigned 2018 version is hugely important as the brandâs grandest offering.