Several reports demonstrate unexplained consequences of mutations on the expression of the different dystrophin isoforms and their balance. The most prominent example is found in some cases of X-linked dilated cardiomyopathy (XLDC).
In particular, calcitonin has the ability to decrease blood calcium levels at least in part by effects on two well-studied target organs: 1  Bone: Calcitonin suppresses resorption of bone by inhibiting the activity of osteoclasts, a cell type that digests bone matrix, releasing calcium and phosphorus into blood.
Calcitonin levels may be ordered when someone is suspected of having C-cell hyperplasia or medullary thyroid cancer. A person may experience signs and symptoms, such as: 1  A lump or swelling at the front of the neck. 2  Pain at the throat or front of the neck.