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Physical symptoms of neurological problems may include the following: 1  Partial or complete paralysis. 2  Muscle weakness. 3  Partial or complete loss of sensation. 4  Seizures. Difficulty reading and writing.  Poor cognitive 1  abilities. Unexplained 2  pain. Decreased alertness.
Early symptoms of motor neurone disease are often mild. They may include: 1  stumbling due to weakness of the leg muscles. 2  difficulty holding objects due to weakness of the hand muscles. 3  slurring of speech or swallowing difficulties due to weakness of the tongue and throat muscles.hey may include: 1  stumbling due to weakness of the leg muscles. 2  difficulty holding objects due to weakness of the hand muscles. 3  slurring of speech or swallowing difficulties due to weakness of the tongue and throat muscles.