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How It Works. Leflunomide (Arava) is a disease-modifying antirheumatic drug (DMARD) that is used to treat rheumatoid arthritis. It interferes with the progression of the disease by blocking the production of white blood cells that cause the joint inflammation in rheumatoid arthritis.
Take the minimum amount. Use the smallest possible dose to start, and only increase it if you need more relief. If the recommended amount doesnât do enough to ease your arthritis, ask your doctor for other pain relief options. Increasing your daily dose even a little beyond the 4,000 mg maximum may cause liver damage.