One of the most controversial forms of depression treatment is electroconvulsive therapy or ECT. These treatments for depression have been around for several decades but have improved significantly over the years in terms of both safety and effectiveness.
(Redirected from Diphacinone). Diphenadione is a vitamin K antagonist which has anticoagulant effects and is used as a rodenticide against rats, mice, voles, ground squirrels and other rodents.This chemical compound is an anti-coagulant with longer activity than warfarin and other synthetic indandione anticoagulants.iphenadione is highly toxic for human skin by all means of contact. Consumption of the drug may cause major blood clotting abnormalities and irregular heartbeats. An online pesticide database gives more information about the safety of diphenadione.
The oral LD50 for technical diphacinone in rats is 0.3 to 7 mg/kg, 3.0 to 7.5 mg/kg in dogs, 14.7 mg/kg in cats, 150 mg/kg in pigs, 50 to 300 mg/kg in mice, and 35 mg/kg in rabbits (2, 3, 4).The dermal LD50 in rats is 200 mg/kg (4), and in rabbits is greater than 3.6 mg/kg.iphacinone does not irritate the skin and it is not a skin sensitizer (2). It is a mild eye irritant. The amount of a chemical that is lethal to one-half (50%) of experimental animals fed the material is referred to as its acute oral lethal dose fifty, or LD50.