Patients with renal failure, usually end-stage renal disease (ESRD), commonly are afflicted by severe pruritus. The pathogenesis of ESRD pruritus is unknown, but improving the quality of dialysis can reduce the prevalence and severity of ESRD pruritus.
The earlier generation of Buick Park Avenue ran from 1991 through 1996, with substantial updates for the 1994 model year. It shared its underpinnings with the Oldsmobile 98, that make's largest sedan, as well as a number of Cadillac front-wheel-drive sedans.
Notable changes during the original Buick LaCrosse's run began in 2006, when head-protecting side curtain airbags and antilock brakes became standard on all models. The Super joined the lineup for 2008, while Bluetooth was added (and the CXS model dropped) for 2009, the last year of production.