Patients with renal failure, usually end-stage renal disease (ESRD), commonly are afflicted by severe pruritus. The pathogenesis of ESRD pruritus is unknown, but improving the quality of dialysis can reduce the prevalence and severity of ESRD pruritus.
The earlier generation of Buick Park Avenue ran from 1991 through 1996, with substantial updates for the 1994 model year. It shared its underpinnings with the Oldsmobile 98, that make's largest sedan, as well as a number of Cadillac front-wheel-drive sedans.
The first-generation Buick LaCrosse was produced for the 2005-'09 model years. Its basic platform was similar to that of a few other General Motors products, including the Pontiac Grand Prix. Its highlights were available six-passenger seating (with a front bench seat), a large trunk and a soft, isolated and quiet ride.