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The Replicated Man holotapes are a series of holotapes in Fallout 3, all simply called Holotape in the game. They are directly related to the quest The Replicated Man and can be found all over the Capital Wasteland.
Man is a eukaryotic organism. This means that the genetic material of human cells is present in a delimited nucleus and in the mitochondria (specialised organites). Like humans, yeast is a eukaryotic organism, as opposed to procaryotic organisms such as bacteria. But contrary to humans, made up of billions of cells, yeast is unicellular! That is why it is easier to study and handle.