In winter, the weather outside is cold and people are dressed warmly, so a much lower indoor temperature such as 62 feels warm enough. In summer when wearing light clothes, cold AC is absolutely miserable! Summer indoor temperatures should be between 80 and 86 degrees.
The pinprick pupils are caused by mu receptor activation, and reversed (as we all know) during mu receptor antagonism or withdrawal. The pupil size is a good indicator of the subjective experience. If a person has low or no opiate tolerance, buprenorphine will cause the person to feel an opiate 'high', and will constrict the pupils. If a person is taking buprenorphine every day, appropriately, there is no high, and the pupils are not affected. If a person is using high doses of oxycodone or heroin and takes buprenorphine, the person will feel lousy, i.e.precipitated withdrawal, and the pupils will be very large.
Buprenorphine effects on the heart and heart rate. Other than a predicted slowdown of the heart beat, buprenorphine users are not exposed to any major heart related dangers. Buprenorphine effects on blood pressure. Decreased blood pressure, dizziness and fainting are reported as a possible side effects of using buprenorphine. Also, hypertension has been reported as a serious side effect which requires urgent medical assistance.