ESTRING (estradiol vaginal ring) PLACEMENT. The exact position of ESTRING (estradiol vaginal ring) is not critical, as long as it is placed in the upper third of the vagina. When ESTRING (estradiol vaginal ring) is in place, you should not feel anything.he soft, flexible ring is placed in the upper third of the vagina (by the physician or the patient). ESTRING (estradiol vaginal ring) should be removed after90 days of continuous use. If continuation of therapy is indicated, the flexible ring should be replaced.
Fertilization takes place in the fallopian tube, more specifically the juncture of the ampulla and isthmus (ampullary-isthmic junction). The ovaries will ovulate and expel a mature ovum due to a surge in the Leutenizing Hormone.
  fallopian tubes In the human body, fertilization of egg cells occur in the oviduct (also called the fallopian tube) of the female's reproductive system.s the egg travels travel down,  the sperm cells are released from the oviduct wall and continue  their journey to the egg. The long and short of it is that  fertilization finally occurs in the ampula or wider section of the  oviduct closer to the ovary.