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Lexapro has a half-life of 27-32 hours and I think is totally out of your system in about 6 days.
Best Answer: I called the pharmacy about this when I was put on Lexapro. He said that I may want to take it at night instead of in the mornings.It will take about two weeks to fully get into your system. If I forget to take it at night, I will take it in the morning, and now it doesn't make me tired.kay, my dr told me to take lexapro in the morning but it makes me so tired and end up taking a nap to feel rested, i thought about just taking it at night around 7 or 8 is it better to take at night what do you think!