The cause of irritable bowel syndrome is unknown. Antibiotic-associated colitis usually occurs in people receiving antibiotics. Inflammatory bowel diseases is a common cause of bowel inflammation and low back pain. There are two major forms: Crohns disease and ulcerative colitis. The causes are unknown. â¢Genetic: There is a high similarity of symptoms among identical twins, particularly with Crohn disease.
An effective dose (ED) in pharmacology is the dose or amount of drug that produces a therapeutic response or desired effect in some fraction of the subjects taking it.D50 [edit]. The median effective dose is the dose that produces a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). It is also sometimes abbreviated as the ED50, meaning effective dose, for 50% of people receiving the drug.
Describe a typical dose-response curve for a drug, and label the positions on the curve that are used to define drug potency vs efficacy. Explain the difference between selectivity and specificity of drug effect, and which is more commonly observed.