SNAREs are integral membrane proteins (v-SNAREs on vesicles, t-SNAREs on the target organelles) and are thought to provide specificity to the fusion process1â5. It has been suggested that Sec17p and SeclSp bind to v-SNARE/t-SNARE complexes and mediate the membrane fusion event1â3.
In 2015, 4,976 people died in motorcycle crashes, up 8.3 percent from 4,594 in 2014, according to the National Highway Traffic Safety Administration (NHTSA). In 2014, motorcyclists were 27 times more likely than passenger car occupants to die in a crash per vehicle mile traveled, and almost five times more likely to be injured.
Cycling has often been dismissed as something that cannot possibly be safe, however looking at the numbers disproves that claim. According to the US Department of Transportation, only 741 cyclists were killed in traffic accidents in 2013. In that same year, 32,719 people were killed in car accidents. There are two things to take away from this. First, cycling is a safe and efficient alternative to traveling by car locally.