Halloween (DÃ­a de las Brujas) is hailed mainly as a childrenâs festivity in Mexico on October 31. It is often overshadowed by the Day of the Dead (DÃ­a de los Muertos) celebrations on All Saintsâ Day and All Soulâs Day. Halloween coincides with Day of the Dead preparations in Mexico City, late October.Halloween coincides with Day of the Dead preparations in Mexico City, late October.Â©iStockphoto.com/abalcazar.
Colchicine is a medication most commonly used to treat gout. It is a toxic natural product and secondary metabolite, originally extracted from plants of the genus Colchicum (autumn crocus, Colchicum autumnale, also known as meadow saffron).Adverse effects are primarily gastrointestinal upset at high doses.vailability of tubulin is essential to mitosis, so colchicine effectively functions as a mitotic poison or spindle poison. The mitosis-inhibiting function of colchicine has been of great use in the study of cellular genetics.
Associate Professor, Case Western Reserve University School of Medicine; Clinical Specialist in Family Medicine, University Hospitals, Case Medical Center, Cleveland, Ohio. Colchicine is currently approved for prophylaxis and treatment of acute gout exacerbations. Colchicine is also approved for the treatment of familial Mediterranean fever.