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High triglyceride causes include a number of factors, some of which are controllable. A high triglyceride count is usually caused by obesity, poorly controlled diabetes, an underactive thyroid, kidney disease, unhealthy diet (eating more calories than are burned), and drinking a lot of alcohol.ne needs some triglycerides for good health, but high triglycerides can increase the risk of heart disease, diabetes and stroke. It may also be a sign of metabolic syndrome, which is the combination of high blood pressure, high blood sugar, too much fat around the waist, and high triglycerides.
With weight gain, repeatedly elevated cortisol can cause stored triglycerides to be relocated to the visceral fat cells, primarily the ones in the abdomen and under muscle. It also causes fat cells to mature, which may result in increased amounts of cortisol produced at the tissue level.