Simpson explores the history and issues surrounding the Hetch Hetchy dam at Yosemite National Park, which was built to supply San Francisco with water and power even though the site was already protected within the national park.
Dapsone, also known as diaminodiphenyl sulfone (DDS), is an antibiotic commonly used in combination with rifampicin and clofazimine for the treatment of leprosy.ral dapsone was one of the first medications used to treat moderate to severe acne vulgaris, and is still occasionally prescribed for the treatment of severe cases. A topical form of dapsone is also effective with potentially less side effects.
agents have been associated with aplastic anemia, but it is difficult to prove whether there is a causal relationship, given the absence of conï¬rmatory cases. [3] Dapsone is a drug that is known to be associated with serious hematological ADR, including agranulocytosis, [4] hemolytic anemia and, [6, 7] more rarely, aplastic anemia. [8, 9] Aplastic anemia seen with dapsone may be either of two types; early or late. Early onset bone marrow toxicity is usually detected during or shortly after drug exposure, may be dose-related, and is usually reversible. Late onset aplastic anemia does not depend on the dose and duration of exposure, and is irreversible.