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Take pain medication. Taking an over-the-counter medication is one of the most effective ways to make cramps go away. Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and Tylenol work quickly to take away the pain. You can find them in most drug stores.
1 If you get cramps rest and stretch them out. 2  Restore potassium, magnesium and calcium concentration in your blood. 3  For example, eat more bananas, peaches, cheese like cheddar, dried apricots, chocolates, cod liver, seafood, etc.ress this spot with your thumb, the heel of your hand, or a loosely clenched fist. Hold the pressure for 10 seconds, ease off for about 10 seconds, then press again. You should feel some discomfort but not excruciating pain.