According to The Hollywood Reporter, the four voice actors who make up the Family Guy cast -- Alex Borstein, Mila Kunis, Seth Green and Mike Henry -- has collectively negotiated a new salary between $175,000 and $225,000 per episode.
Hence, a patient with first degree heart block will typically have a soft first heart sound. For the same reasons a patient with variable PR interval (Mobitz I second degree AV block or third degree heart block) can have changing intensity of the first heart sound. Lyme carditis, anatomically corrected transposition and maternal lupus can all cause complete heart block.
First Heart Sound. The first heart sound (S 1) is produced by vibrations generated by closure of the mitral (M 1) and tricuspid valves (T 1). It corresponds to the end of diastole and beginning of ventricular systole and precedes the upstroke of carotid pulsation. Refer to the audio example below.