Chromosome instability usually leads to tumorigenesis. Bloom syndrome (BS) is a genetic disease associated with chromosome instability. The BS gene product, BLM, has been reported to function in the spindle assembly checkpoint (SAC) to prevent chromosome instability.
Flight time from Detroit to Chicago is usually between 45 minutes to one hour.
Non-stop flight time from Chicago, Il to Dallas, TX is between 2 hrs to 2 hrs 45 mins depending on the aircraft's cruising speed, technical condition and weather/wind speed..