Rheumatology: 5. Diagnosis and management of inflammatory polyarthritis. Dr. Klinkhoff is Assistant Clinical Professor, University of British Columbia, Medical Director at the Mary Pack Arthritis Centre and is with the Arthritis Research Centre of Canada, Vancouver, BC.
How does transcription differ from DNA synthesis? The primary difference between transcription and DNA replication is that only a single strand of mRNA is produced during transcription. During DNA replication both strands need to be copied and DNA polymerase needs to work on both strands at the same time.Because DNA polymerase can only add new bases onto the free 3â end of a molecule the two strands cannot be synthesized in the same way.ow does transcription differ from DNA synthesis? The primary difference between transcription and DNA replication is that only a single strand of mRNA is produced during transcription. During DNA replication both strands need to be copied and DNA polymerase needs to work on both strands at the same time.
During transcription, a strand of mRNA is formed that is complementary to the sequence within the DNA. Transcription begins when RNA polymerase binds to the DNA promoter for a gene. The DNA helix is unwound and the primary mRNA strand is made by RNA polymerase.