duete; see due, ty 2 ]. syn: duty, obligation refer to something a person feels bound to do. A duty often applies to what a person performs in fulfillment of the permanent dictates of conscience, piety, right, or law: one's duty to tell the truth; a parent's duty to raise children properly.
Mutations in the RB1 gene are responsible for most cases of retinoblastoma. RB1 is a tumor suppressor gene, which means that it normally regulates cell growth and keeps cells from dividing too rapidly or in an uncontrolled way.
Symptoms of Retinoblastoma in Children. The most common form of pediatric eye cancer is retinoblastoma, a disease whch affects around 300 children in the U.S. every year. While it is predominately diagnosed in children two years of age and under, it can strike in other age groups, as well..