Chromosome instability usually leads to tumorigenesis. Bloom syndrome (BS) is a genetic disease associated with chromosome instability. The BS gene product, BLM, has been reported to function in the spindle assembly checkpoint (SAC) to prevent chromosome instability.
Flight time from Detroit to Chicago is usually between 45 minutes to one hour.
Consider your self lucky. We did a 3.5 hour flight from Phoenix to Chicago and then did a 9.5 hour flight into Frankfurt and finally did the last leg from Frankfurt to Barcelona, another 2.0 hour flight. By the time we made it to the Barcelona Airport we were pretty tired. I really am jelous that you only have that 1.5 hour flight from Geneva, you got it made. Have a nice trip. Tim and Cathy.