The looping of the template for the lagging strand enables a dimeric DNA polymerase III holoenzyme at the replication fork to synthesize both daughter strands. (Courtesy of A. Kornberg. From L. Stryer, Biochemistry, 4th ed.he 3â²âââ5â² exonuclease action of DNA polymerase III. Note that this exonuclease activity takes place at the 3â² end of the growing strand (and is therefore 3â²âââ5â²). The coordination of exonuclease activity with strand growth helps to explain why replication is in the 5â²âââ3â² direction.
McAllen is the twenty-first most populous city in Texas and the largest city in Hidalgo County, Texas. It is located at the southern tip of Texas in the Rio Grande Valley (not a geographical valley) and is part of the Southern United States.
McAllen, TX has a population of 135,048 and is the 191st largest city in the United States. The population density is 2,739 per sq mi which is 2744% higher than the Texas average and 2923% higher than the national average. The median age in McAllen is 33 which is approximately 4% lower than the Texas average of 34. In McAllen, 58% of the population over 15 years of age are married, 20% speak English and 77% speak Spanish. 59% of McAllen residents were born in Texas, 11% were born out of state, 1% were born outside of the United States and 29% were foreign born.