An argument for a mathematics program that is more compatible with the nature of the learner is therefore an argument for a greater degree of involvement with manipulative materials and exploitation of appropriate mathematical applications.
The Germ theory of disease, developed in the 1860s and 1870s by Louis Pasteur, states that tiny living beings are the cause of infectious diseases. The theory was developed to explain puerperal fever, or Child bed fever.
Although Pasteur was not the first to propose the germ theory, he developed it and conducted experiments that clearly indicated its correctness and managed to convince most of Europe that it was true.