Warfarin (Coumadin) is sometimes prescribed as a blood thinner because it is an effective vitamin K antagonist (blocks the formation of vitamin K). The activated partial thromboplastin time (PTT) measures the function of several other clotting factors, found in the intrinsic and common blood clotting pathways.
Etruscans and the early Roman monarchy made several contributions to the Roman republic. The establishment of Rome was through Romulus and Remus. Through legends, they were thought to be abandoned by their uncle, and raised up by a she wolf.
For a time, they were under the control of their neighbours, the Etruscans. Rome became a rich city, ruled by kings. In 509 BC, the Romans drove out their last king, Tarquin the Proud. Rome then became a republic. The republic was ruled by a Senate.