Umeclidinium and vilanterol is for use only in people with chronic obstructive pulmonary disease (COPD) and should not be used to treat asthma. Vilanterol may increase the risk of death in people with asthma, but the risk in people with COPD is not known.
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Wikipedia:Manual of Style/Lead section. The lead section (also known as the lead or introduction) of a Wikipedia article is the section before the table of contents and the first heading. The lead serves as an introduction to the article and a summary of its most important contents. It is not a news-style lead or lede paragraph. The lead is the first part of the article that most people will read. For many, it may be the only section that they read.