DNA polymerases need a primer oligonucleotide (RNA or DNA) - their substrates are an existing 3'-OH group and a dNTP. The primase however is a typical RNA polymerase, capable of initiating polynucleotide synthesis de novo by positioning a complementary ribonucleoside 5'-triphosphate opposite its complementary DNA base.
Alison Schapker. Alison Schapker is an American television writer and producer. She is well known for her work on the ABC espionage series Alias and for the FOX science-fiction series Fringe.
'Nasty Nellie' Alison Arngrim talks 'Little House on the Prairie' days, reveals what she's up to now. After decades of best being recognized the bratty Nellie Oleson from Little House on the Prairie, Alison Arngrim is having fun playing Bewitched star Erin Murphyâs wife.