These problems can be mitigated through the process of design, which is an intellectual approach that emphasizes empathy, abductive reasoning, and rapid prototyping. Horst Rittel, one of the first to formalize a theory of wicked problems, cites ten characteristics of these complicated social issues Rittel, Horst. Dilemmas in a General Theory of Planning.. Policy Sciences, 1973: 155-169.
Increased ADH levels are often associated with SIADH, which may be due to a variety of cancers, including leukemia, lymphoma, and cancers of the lung, pancreas, bladder, and brain. Levels of ADH may be greatly increased with such cancers.
May experience synergistic effects on potassium elevation with the use of ACE inhibitors, cyclosporine, tacrolimus, and other potassium-sparing diuretics. Concomitant use of NSAIDS may result in decreased diuretic effectiveness and increased potassium levels secondary to decreased synthesis of renal prostaglandins.