DNA polymerases need a primer oligonucleotide (RNA or DNA) - their substrates are an existing 3'-OH group and a dNTP. The primase however is a typical RNA polymerase, capable of initiating polynucleotide synthesis de novo by positioning a complementary ribonucleoside 5'-triphosphate opposite its complementary DNA base.
Alison Schapker. Alison Schapker is an American television writer and producer. She is well known for her work on the ABC espionage series Alias and for the FOX science-fiction series Fringe.
In 2006, Schapker was brought on to develop the first season of the ABC drama Brothers & Sisters as a writer and supervising producer. 1  She then went on to become co-executive producer at the start of season two, and then held the position of executive producer throughout seasons three and four.