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Venereal disease: A disease that is contracted and transmitted by sexual contact, caused by microorganisms that survive on the skin or mucus membranes, or that are transmitted via semen, vaginal secretions, or blood during intercourse.he genital areas provide a moist, warm environment that is especially conducive to the proliferation of bacteria, viruses, and yeasts, so a great many diseases can be transmitted this way, including AIDS, chlamydia, genital warts, gonorrhea, syphilis, yeast infections, and some forms of hepatitis.
The term venereal disease is much less used today, while sexually transmitted diseases is slowly giving way to sexually transmitted infections, because the last term has a broader range of meaning-a person can pass on the infection without having a disease (they do not have to be ill to infect other people).