Chromosome instability usually leads to tumorigenesis. Bloom syndrome (BS) is a genetic disease associated with chromosome instability. The BS gene product, BLM, has been reported to function in the spindle assembly checkpoint (SAC) to prevent chromosome instability.
Flight time from Detroit to Chicago is usually between 45 minutes to one hour.
For those of you who are curious but don't have the patience for such a flight, we sent USATODAY.com air travel reporter Ben Mutzabaugh to give you a first-hand recap on a 15-hour non-stop flight from Chicago to New Delhi.