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The forms of human malaria caused by other Plasmodium species cause significant morbidity but are rarely life-threatening. Cases of severe P. vivax malaria have recently been reported among populations living in (sub)tropical countries or areas at risk. P. vivax and P. ovale can remain dormant in the liver. Relapses caused by these persistent liver forms (âhypnozoitesâ) may appear months, and rarely several years, after exposure.
P. malariae is the only human malaria parasite that causes fevers that recur at approximately three-day intervals (therefore occurring evey fourth day, a quartan fever), longer than the two-day (tertian) intervals of the other malarial parasites.he ring stages that are formed by the invasion of merozoites released by rupturing liver stage schizonts are the first stages that appear in the blood. The ring stages grow slowly but soon fill one-fourth to one-third of the parasitized cell.