Its analgesic effects are only partially reversed by naloxone, hence indicating that its opioid action is unlikely the sole factor; tramadol's analgesic effects are also partially reversed by Î±2 adrenergic receptor antagonists like yohimbine and the 5-HT3 receptor antagonist, ondansetron.
Array formulas in versions before Excel 2007 cannot handle whole-column references. In Excel 2007, array formulas can handle whole-column references, but this forces calculation for all the cells in the column, including empty cells. This can be slow to calculate, especially for 1 million rows.
Starting in Excel 2007, you should always use the SUMIFS, COUNTIFS, and AVERAGEIFS functions instead of array formulas where you can because they are much faster to calculate. In versions before Excel 2007, array formulas are often used to calculate a sum with multiple conditions.