Myalgia is not a medical disorder or disease but more of a symptom of an existing underlying condition. Myalgia is known as a muscle ache or muscle pain. It is a common condition that almost everyone has had at one time or another. The pain in the muscle can last a just a few days or for much longer.
H2 receptors are positively coupled to adenylate cyclase via Gs. It is a potent stimulant of cAMP production, which leads to activation of Protein Kinase A. PKA functions to phosphorylate certain proteins, affecting their activity.The drug betazole is an example of a Histamine H 2 receptor agonist.he histamine receptor H 2 belongs to the rhodopsin-like family of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation.
Purinergic receptors are divided into P2 receptors which are activated by a variety of nucleotides and can be further subdivided into ionotropic P2X receptors activated by ATP and the metabotropic G-protein-coupled receptors (P2Y) which are stimulated by nucleotides, di-or triphosphates, purines or pyrimidines.he role of P1 receptors in MSC proliferation is not well studied. There is some evidence suggesting that adenosine and the adenosine A2A receptor are important mediators in stimulating proliferation and differentiation of mouse BM-MSCs [96] .