Chromosome instability usually leads to tumorigenesis. Bloom syndrome (BS) is a genetic disease associated with chromosome instability. The BS gene product, BLM, has been reported to function in the spindle assembly checkpoint (SAC) to prevent chromosome instability.
Flight time from Detroit to Chicago is usually between 45 minutes to one hour.
US Airways has 410 connecting flights between Chicago, IL and Detroit. 19,038 seats are available per week to fly direct from Chicago, IL to Detroit. 4 airlines operate between Chicago, IL and Detroit.