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Ibuprofen is not safe for continuous, daily, long-term use due to its affect on the liver, kidneys and blood pressure.Watch pain management expert Devi Nampiaparampil, MD, explain how too much ibuprofen can have a negative impact over time.t can also increase the risk of bleeding in the stomach. Your doctor will need to regularly test your urine and blood if you are taking ibuprofen long-term. Over-the-counter ibuprofen should not be used for more than 10 days to treat body aches, unless directed to do so by your doctor.
A: Taking 800 mg three times a day of ibuprofen is okay for a short period of time, a month or two, or even longer if under supervision of a physician. The only issue is if there is a history of heart disease, the patient should not take it over six weeks.