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gist - the central meaning or theme of a speech or literary work. 2. gist - the choicest or most essential or most vital part of some idea or experience; the gist of the prosecutor's argument; the heart and soul of the Republican Party; the nub of the story.
: the general or basic meaning of something said or written â usually + of. 1  The gist of her argument was that the law was unfair. 2  I didn't read the whole article, but I got the gist of it. [=I understood the main points of it]