Signs and symptoms of peripheral neuropathy might include: 1  Gradual onset of numbness, prickling or tingling in your feet or hands, which can spread upward into your legs and arms.  Sharp, jabbing, throbbing, freezing or burning pain.
Case Study of Adjacent Segment Disease. A patient with a 2-year-old anterior cervical discectomy and fusion at the c5-c6 level presents with pain in the neck, or cervical spine, increased with movement. MRI findings indicate clinically significant disc disease in the levels adjacent to the cervical fusion at C4-C5 and C6-C7.
These cases of parkinsonism may be difficult to distinguish from idiopathic Parkinsonâs disease especially early in the course the disease. Arguably the most prominent of type of atypical parkinsonismâor Parkinson plus conditionsâis multiple system atrophy (MSA), whose subtypes include: MSA-A, MSA-C, and MSA-P. As they present similar to Parkinsonâs disease, it is important to differentiate them from Parkinsonâs disease as well as from each other. On a histological level, MSA exhibits glial cytoplasmic inclusions on biopsy rather than the Lewy bodies seen in Parkinsonâs disease.