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White matter is located at the base of the brain between the cerebellum and the brainstem. It is made of long nerve fibers called axons. The axons are insulated by myelin, sheaths of fat that give the region the white color for which it is named. The myelin helps speed up the transmission of signals along the axons.
The largest and most obvious parts of the human brain are the cerebral hemispheres. The cerebrum has an outer layer - the cortex, which is composed of neurons and their supporting cells, and in living brain, has a gray color thus called the gray matter.