PRESCRIBER PROCEDURE  To initiate the prior authorization process, the prescriber must call the prior authorization phone line at 1-877-309-9493 and select Option â1â for Prescriber.  Select Option â2â to obtain a prior authorization for a brand-name drug.
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A ubiquitin ligase (also called an E3 ubiquitin ligase) is a protein that recruits an E2 ubiquitin-conjugating enzyme that has been loaded with ubiquitin, recognizes a protein substrate, and assists or directly catalyzes the transfer of ubiquitin from the E2 to the protein substrate.TP + ubiquitin + protein lysine AMP + diphosphate + protein N-ubiquityllysine. The 3 substrates of this enzyme are ATP, ubiquitin, and a lysine residue on a protein, whereas its 3 products are AMP, diphosphate, and protein N-ubiquityllysine.