Less serious side effects include: 1  Loss of appetite. 2  Weight loss. 3  Nausea. 4  Vomiting. 5  Diarrhea. 6  Frequent urination. 7  Muscle cramps, painful and swollen joints. 8  Excessive tiredness. 9  Difficulty falling asleep. 10  Headache, nervousness, dizziness. 11  Depression, mood swings. 12  Vivid dreams.
Nausea can occur in dogs for many reasons, particularly when the digestive tract and nervous systems are out of balance. Stress can certainly play a role in nausea.
Dogs with chronic leukemia may or may not require such intensive supportive care, although antibiotics are often part of their treatment protocol, as well. The classic treatment for canine leukemia is chemotherapy. Chemotherapy involves treating the disease with anti-cancer drugs that target rapidly dividing or growing cells. Unfortunately, the cells lining the gastrointestinal tract are normally rapidly dividing and growing, which is why chemotherapeutic treatment is often associated with nausea, vomiting, diarrhea and other forms of gastrointestinal distress.