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Best Answer: unduplicated chromosomes are single linear strands, whereas duplicated chromosomes (copied during synthesis phase) contain two copies joined by a centromere.(centromere is a region of DNA t found near the middle of a chromosome where two identical sister chromatids come in contact).
A chromosome is a single large macromolecule of DNA, and is the basic 'unit' of DNA in a cell. It is a very long, continuous piece of DNA (a single DNA molecule), which contains many genes, regulatory elements and other intervening nucleotide sequences. In some circumstances chromosome also refers to the DNA bound proteins which package and manage the DNA.