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Many people report upset stomach and diarrhea after consuming normal amounts of erythritol in food or beverages. If consumption is high (50 grams or more per day) then digestive troubles, including gas, cramping, bloating, stomachache and diarrhea, become even more likely. One study specifically showed that the intake of 50 grams of erythritol causes stomach rumbling and nausea.
Viruses (e.g., adenovirus, astrovirus, rotavirus, Norwalk virus) are the most common cause of diarrhea in the United States. The most common ones in children are rotavirus and in adults are norovirus. Escherichia coli, Clostridium difficile, and Campylobacter, Salmonella, and Shigella spp. are common bacterial causes.