Peripheral vascular disease is a manifestation of systemic atherosclerosis that leads to significant narrowing of arteries distal to the arch of the aorta. The most common symptom of peripheral vascular disease is intermittent claudication. At other times, peripheral vascular disease leads to acute or critical limb ischemia. Intermittent claudication manifests as pain in the muscles of the legs with exercise; it is experienced by 2 percent of persons older than 65 years.
Symptoms of GERD-related Cough. There are certain clues to suggest that a persistent cough may be actually due to GERD. A GERD-related cough usually occurs during the night or after a meal (when acid reflux often is at its worst). Coughing can also occur when you are lying down. If you do not find any X-ray reports to suggest that the reason might be something else or the cough happens without post-nasal drip or asthma, it could be related to GERD.
1 A productive cough could be a sign that a disease such as chronic obstructive pulmonary disease (COPD) is getting worse or that you have an infection.  Stomach acid backing up into the esophagus . This type of coughing may be a symptom of gastroesophageal reflux disease (GERD) and may awaken you from sleep.