Various conditions can lead to irritated, red skin. Causes can range from a temporary sensitivity to a chronic skin problem. Common culprits of red skin or red spots include: 1  Dry skin. 2  Sunburn. 3  Rosacea. 4  Acne. 5  Allergic contact dermatitis. 6  Eczema (atopic dermatitis).
Methylene blue is a component of a frequently prescribed urinary analgesic/anti-infective/anti-spasmodic known as Prosed, a combination of drugs which also contains phenyl salicylate, benzoic acid, hyoscyamine sulfate, and methenamine (aka hexamethylenetetramine and not to be confused with 'methanamine').
Together these studies demonstrate a consistent benefit of methylene blue administered at three different times (preoperative, intraoperative, and postoperative) during the perioperative period. The small sample size of the current study limits conclusions regarding the safety of methylene blue. However, our results in conjunction with other studies suggest that methylene blue can be administered with relatively few adverse effects.