Definition of retraction. Examples of retraction in a sentence. His charges were false, and he was forced to make a retraction. Then, last spring, Gabriel Arana, an editor at The American Prospect who had undergone several years of reparative therapy in his teens, called on Spitzer at his home in Princeton, New Jersey.
2010]. Grapefruit juice inhibited the first-pass metabolism of oxycodone by CYP3A4 enzymes in the liver; consequently, oxycodone plasma concentrations were significantly increased by 50% and the half-life was extended by 20%.
Grapefruit's culprit chemical does not interact directly with your pills. Instead, it binds to an enzyme in your intestinal tract known as CYP3A4, which reduces the absorption of certain medications. When grapefruit juice blocks the enzyme, it's easier for the medication to pass from your gut to your bloodstream.