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Typhoid fever is treated with antibiotics which kill the Salmonella bacteria. Prior to the use of antibiotics, the fatality rate was 20%. Death occurred from overwhelming infection, pneumonia, intestinal bleeding, or intestinal perforation. With antibiotics and supportive care, mortality has been reduced to 1%-2%.
Treatment of typhoid feverâ  (enteric fever) or septicemia caused by Salmonella typhi or S. paratyphiâ , including multidrug-resistant strains.188 267 292 406 407 408 409 410 419 A drug of choice for empiric treatment of enteric fever pending results of in vitro susceptibility tests.292.