Sections. By Mark Flood, D.O. Annular tear symptoms can arise when the annulus fibrosus (the tough exterior) of an intervertebral disc rips. The outer layers of the annulus fibrosus near the vertebral endplates are replete with nerve fibers that are very sensitive to pain.ections. By Mark Flood, D.O. Annular tear symptoms can arise when the annulus fibrosus (the tough exterior) of an intervertebral disc rips. The outer layers of the annulus fibrosus near the vertebral endplates are replete with nerve fibers that are very sensitive to pain.
Those of us who are deficient and start on a vitamin D supplement usually take five to six weeks to reach the recommended level of vitamin D. If you're in doubt, it's always best to have a chat with your GP who might arrange a blood test. The B vitamins and vitamin C are all water soluble.
Those who report two or more leg cramps in each week will continue in the study and will be randomized to vitamin D or placebo. After a two-week wash-in, subjects will take a vitamin D capsule (50,000 units) once daily for 10 days, followed by a once weekly vitamin D (50,000 units) maintenance dose for 7 weeks.