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What do I need to know about Vitamin K, if I am taking warfarin (Coumadin)? Changes in the amount of vitamin K in the diet can alter the metabolism of warfarin (Coumadin Â®). However, vitamin K does not influence the action of other blood thinners, such as heparin or low molecular weight heparins (Lovenox Â®. Fragmin Â®, or Innohep Â®).
Vitamin K helps in the activation of seven blood-clotting-factor proteins that participate in a series of reactions to form a clot that eventually stops the flow of blood. Vitamin K also participates in the activation of bone proteins, which greatly enhances their calcium-binding properties.oxicity. High doses of vitamin K can reduce the effectiveness of anticoagulant drugs such as warfarin (Coumadin), which is used to prevent blood clotting. People taking these drugs should maintain a consistent daily intake of vitamin K. Megadose supplements of vitamin A and E can pose a risk to vitamin-K status.