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Chronic kidney disease (CKD) is a long-term condition where the kidneys do not work effectively. CKD does not usually cause symptoms until it reaches an advanced stage. It is usually detected at earlier stages by blood and urine tests. Main symptoms of advanced kidney disease include: 1  tiredness. 2  swollen ankles, feet or hands (due to water retention).
Coding Chronic Kidney Disease. Chronic kidney disease (CKD) affects 20 million Americans, or one in every nine adults, and another 20 million Americans are at risk of developing CKD, according to the National Kidney Foundation.