An argument for a mathematics program that is more compatible with the nature of the learner is therefore an argument for a greater degree of involvement with manipulative materials and exploitation of appropriate mathematical applications.
The Germ theory of disease, developed in the 1860s and 1870s by Louis Pasteur, states that tiny living beings are the cause of infectious diseases. The theory was developed to explain puerperal fever, or Child bed fever.
However, at the root of all of this, there are the theories that we base our medical knowledge on. These theories, the humoral concept of disease, the anatomical theory of disease, and germ theory are what has lead us to modern medicine, and changed not only how we see and treat disease, but also the human body. The humoral concept can be traced back to Hippocrates (490 to 377 B.C.) of ancient Greece.