Chromosome instability usually leads to tumorigenesis. Bloom syndrome (BS) is a genetic disease associated with chromosome instability. The BS gene product, BLM, has been reported to function in the spindle assembly checkpoint (SAC) to prevent chromosome instability.
Flight time from Detroit to Chicago is usually between 45 minutes to one hour.
Flight time from Chicago, Il to Berlin via London â¢ ORD to TXL via LHR. Flight duration from Chicago O'hare International Airport to Berlin-tegel / Otto Lilienthal Airport via London Heathrow Airport, United Kingdom on Finnair flight is 13 hours 25 minutes.