Chromosome instability usually leads to tumorigenesis. Bloom syndrome (BS) is a genetic disease associated with chromosome instability. The BS gene product, BLM, has been reported to function in the spindle assembly checkpoint (SAC) to prevent chromosome instability.
Flight time from Detroit to Chicago is usually between 45 minutes to one hour.
Flight time from Chicago, Il to Berlin via Amsterdam â¢ ORD to TXL via AMS. 1  Flight duration from Chicago O'hare International Airport to Berlin-tegel / Otto Lilienthal Airport via Amsterdam-Schiphol Airport, Netherlands on Delta Air Lines flight is 9 hours 55 minutes.