Related articles: Deck, Landscape Design, Sod. 1  Prices for underground sprinkler systems vary considerably by region and climate, but for an average 2,500-square-foot (50-x-50-foot) front yard, it's about $1,500-$2,500, while a sprinkler system for 5,000 square feet (front and back yards) costs about $2,500-$3,500.
Mitochondrial DNA depletion syndrome. Mitochondrial DNA depletion syndrome (MDS) refers to a group of autosomal recessive disorders which cause the affected tissues to suffer from a significant drop in mitochondrial DNA. Symptoms may manifest as myopathic, hepatopathic, and/or encephalomyopathic.
Pyruvate dehydrogenase deficiency (also known as pyruvate dehydrogenase complex deficiency or PDCD) is one of the most common neurodegenerative disorders associated with abnormal mitochondrial metabolism.he most commonly seen form of PDCD is caused by mutations in the X-linked E1 alpha gene and is approximately equally prevalent in both males and females. However, a greater severity of symptoms tends to affect males more often than heterozygous females.