Chromosome instability usually leads to tumorigenesis. Bloom syndrome (BS) is a genetic disease associated with chromosome instability. The BS gene product, BLM, has been reported to function in the spindle assembly checkpoint (SAC) to prevent chromosome instability.
Flight time from Detroit to Chicago is usually between 45 minutes to one hour.
The approximate driving time and mileage information -    Between: Chicago, IL  and: Detroit, MI  Driving miles: 285  Driving time: 4 hrs 45 mins    - is based â¦ on traveling non-stop in good driving conditions.