Details of delusional parasitosis vary among sufferers, but it is most commonly described as involving perceived parasites crawling upon or burrowing into the skin, sometimes accompanied by an actual physical sensation (known as formication). Sufferers may injure themselves in attempts to be rid of the parasites.
Perhaps one of the earliest trials in 1982, gave participants a dose of THC (1 mg/kg), followed by either a dose of valium or of CBD (0.5 mg/kg). The results suggested that CBD had a counteractive effect on THC stimulated anxiety.
Cannabis plant extracts containing 2.5-120 milligrams of a THC-CBD combination have been taken by mouth daily for 2-15 weeks. A mouth spray (SativexÂ®, containing 2.7 milligrams of THC and 2.5 milligrams of CBD) has been used at a dose of 2.5-120 milligrams in divided doses for up to eight weeks. Eight sprays within any three hours, up to 48 sprays in a 24-hour period, have been used. SativexÂ® has been sprayed into the mouth for 6-14 weeks.