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Description of Trazodone. Trazodone: oral antidepressant (trade name Desyrel) that is a nontricyclic drug used as a sedative. Trazodone: A synthetic triazolopyridine derivative, antidepressant and sedative Trazodone acts as a serotonin uptake inhibitor, chemically unrelated to tricyclic, tetracyclic, or other antidepressants.
Trazodone is a popular medication in the substance using patient because it is non-addictive, available as a generic, is not scheduled as a controlled substance, has little risk for overdose and has low risk for life-threatening withdrawal syndromes.