Meth and the Brain. 1  Meth releases a surge of dopamine, causing an intense rush of pleasure or prolonged sense of euphoria. 2  Over time, meth destroys dopamine receptors, making it impossible to feel pleasure. 3  Although these pleasure centers can heal over time, research suggests that damage to users' cognitive abilities may be permanent.
stabilizing. 1  transitive verb. 2  1 : to make stable, steadfast, or firm. 3  2 : to hold steady: such asa : to maintain the stability of (as an airplane) by means of a stabilizerb : to limit fluctuations of (as prices)c : to establish a minimum price for.  intransitive 1  verb. : to become stable, firm, or steadfast.
There is increasing evidence that stress and the resulting depression may involve structural changes in the brain. The good news is that these changes, known as remodeling, can be prevented and potentially reversed with the right treatment, such as antidepressant and mood-stabilizing medications.