An argument for a mathematics program that is more compatible with the nature of the learner is therefore an argument for a greater degree of involvement with manipulative materials and exploitation of appropriate mathematical applications.
The Germ theory of disease, developed in the 1860s and 1870s by Louis Pasteur, states that tiny living beings are the cause of infectious diseases. The theory was developed to explain puerperal fever, or Child bed fever.
(1821-1902).One of the most prominent physicians of the 19th century, German scientist and statesman Rudolf Virchow pioneered the modern concept of the pathological processes of disease. He emphasized that diseases arose, not in organs or tissues in general, but primarily in individual cells.