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Silver sulfadiazine (INN, or silvadene) is a topical sulfonamide / silver antibacterial used as a topical cream on burns.Evidence regarding its usefulness in burns is poor.Tentative evidence has found that silver sulfadiazine may increase healing times â wounds may take longer to heal if treated with this drug, so it is not recommended by the authors of a Cochrane review.Silver sulfadiazine is typically delivered in a cream or aqueous suspension.entative evidence has found that silver sulfadiazine may increase healing times â wounds may take longer to heal if treated with this drug, so it is not recommended by the authors of a Cochrane review.
PRESCRIBED FOR: Silver sulfadiazine is applied to the skin to treat and prevent wound infections associated with second or third degree burns. SIDE EFFECTS: Since silver sulfadiazine is applied to the surface of the skin, it rarely affects other areas of the body or causes long term side effects. Most of the side effects reported with use are short lived and limited to the areas being treated.