It is unusual to find systemic failure in the absence of liver metastases,[1] although the portosystemic shunting that exists at the anorectal junction does permit hematogenous spread outside the portal circulation to the internal iliac vessels and the cava.
A flexible-fuel vehicle (FFV) or dual-fuel vehicle (colloquially called a flex-fuel vehicle) is an alternative fuel vehicle with an internal combustion engine designed to run on more than one fuel, usually gasoline blended with either ethanol or methanol fuel, and both fuels are stored in the same common tank.
Flex engines aren't wildly different from gasoline engines, nor are they space-age technology. The Ford Model T car, for instance, was a flex engine that burned either gas or ethanol. FFVs don't cost more to build, and they aren't more expensive in terms of sticker price, either.