Chromosome instability usually leads to tumorigenesis. Bloom syndrome (BS) is a genetic disease associated with chromosome instability. The BS gene product, BLM, has been reported to function in the spindle assembly checkpoint (SAC) to prevent chromosome instability.
Flight time from Detroit to Chicago is usually between 45 minutes to one hour.
Interesting Facts About Flights from Berlin to Chicago (TXL to ORD) Question : How long does it take to get from TXL to ORD? Answer : Air Berlin currently holds the shortest travel time with nine hours and 35 minutes. For example, you would arrive in Chicago at 12:00 PM CDT if you left Berlin at 9:25 AM CET.