Myalgia is not a medical disorder or disease but more of a symptom of an existing underlying condition. Myalgia is known as a muscle ache or muscle pain. It is a common condition that almost everyone has had at one time or another. The pain in the muscle can last a just a few days or for much longer.
H2 receptors are positively coupled to adenylate cyclase via Gs. It is a potent stimulant of cAMP production, which leads to activation of Protein Kinase A. PKA functions to phosphorylate certain proteins, affecting their activity.The drug betazole is an example of a Histamine H 2 receptor agonist.he histamine receptor H 2 belongs to the rhodopsin-like family of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation.
The discovery of H2-receptors by Black and coworkers opened a new era in the history of histaminology.Their importance became apparent when, soon after their discovery, the physiological role of histamine in the regulation of gastric secretion was clarified.he discovery of H2-receptors by Black and coworkers opened a new era in the history of histaminology.