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Description of Trazodone. Trazodone: oral antidepressant (trade name Desyrel) that is a nontricyclic drug used as a sedative. Trazodone: A synthetic triazolopyridine derivative, antidepressant and sedative Trazodone acts as a serotonin uptake inhibitor, chemically unrelated to tricyclic, tetracyclic, or other antidepressants.
SSRI antidepressants. It is prescribed at lower dosages when used for sleep than for depression, and the brand. name âDesyrelâ is hardly ever used. It is better known to patients by its generic name, trazodone, and this. handout refers to it by its generic name. Besides its use for treatment of insomnia, trazodone was reported to be effective for reducing agitation and. aggression in patients with Alzheimerâs disease and other brain disorders. Also, at low doses, trazodone has an-. tianxiety effects and may be effective in treating generalized anxiety disorder.