Some molecules or particles are too large or too hydrophilic to pass through a lipid bilayer. Other molecules could pass through the bilayer but must be transported rapidly in such large numbers that channel-type transport is impractical.
Vanna White Has the World's Most G-Rated Wardrobe Malfunction on 'Wheel of Fortune'. by 11:56 AM PST, December 11, 2015. Playing Vanna White Has the World's Most G-Rated Wardrobe Malfunction on 'Wheel of Fortune'. Vanna White found herself in a sticky situation during Thursday's Wheel of Fortune. While walking across the stage, the hostess, unbeknownst to her, brought part of the set with her when a prop gift got caught on the bottom of her dress.
The original host of Wheel of Fortune was Chuck Woolery, who hosted the series from its 1975 premiere until December 25, 1981, save for one week in August 1980 when Alex Trebek hosted in his place. Woolery's departure came over a salary dispute with show creator Merv Griffin, and his contract was not renewed.