The looping of the template for the lagging strand enables a dimeric DNA polymerase III holoenzyme at the replication fork to synthesize both daughter strands. (Courtesy of A. Kornberg. From L. Stryer, Biochemistry, 4th ed.he 3â²âââ5â² exonuclease action of DNA polymerase III. Note that this exonuclease activity takes place at the 3â² end of the growing strand (and is therefore 3â²âââ5â²). The coordination of exonuclease activity with strand growth helps to explain why replication is in the 5â²âââ3â² direction.
McAllen is the twenty-first most populous city in Texas and the largest city in Hidalgo County, Texas. It is located at the southern tip of Texas in the Rio Grande Valley (not a geographical valley) and is part of the Southern United States.
Part of this purchase was given to his daughter, Donna Hooks Fletcher, a divorcee. In 1904, The St. Louis, Brownsville, and Mexico Railway reached the area, and a town was formed that July. In 1907, the town was given a depot station that was named Donna in Hooks' honor. Donna is off Interstate 2/U.S. Highway 83 and State Spur 374, fourteen miles (21 km) southeast of McAllen in southeastern Hidalgo County.