DNA polymerases need a primer oligonucleotide (RNA or DNA) - their substrates are an existing 3'-OH group and a dNTP. The primase however is a typical RNA polymerase, capable of initiating polynucleotide synthesis de novo by positioning a complementary ribonucleoside 5'-triphosphate opposite its complementary DNA base.
Alison Schapker. Alison Schapker is an American television writer and producer. She is well known for her work on the ABC espionage series Alias and for the FOX science-fiction series Fringe.
A Little House on the Prairie Star's Family Secret. When Alison Arngrim was 12 years old, she landed the role of Nellie Oleson on Little House on the Prairie. Alison's villainous character was known for her brazen attitude and fearlessness, but in her personal life, Alison says, she was hiding a secret from her loved ones and castmates.