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Fatigue Cause No. 8: Hidden UTI. If you've ever had a urinary tract infection (UTI), you're probably familiar with the burning pain and sense of urgency. But the infection does not always announce itself with such obvious symptoms. In some cases, fatigue may be the only sign. A urine test can quickly confirm a UTI.
From the WebMD Archives. Feb. 3, 2004 -- Low testosterone levels may cause clinical depression in older men, a new study shows. Age related decreases in the male sex hormone testosterone are common in older men; some 30% of men over age 55 have it. Low levels of the hormone can cause symptoms of fatigue, a decreased sex drive, and irritability.