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Erythrocyte deformability refers to the ability of erythrocytes (red blood cells, RBC) to change shape under a given level of applied stress, without hemolysing (rupturing).rythrocyte deformability is an important determinant of blood viscosity, hence blood flow resistance in the vascular system. It affects blood flow in large blood vessels, due to the increased frictional resistance between fluid laminae under laminar flow conditions.
Abstract. The biconcave shape and corresponding deformability of the human red blood cell (RBC) is an essential feature of its biological function. This feature of RBCs can be critically affected by genetic or acquired pathological conditions.eformability of the healthy and spherocyte red blood cells (RBCs) as a function of spectrin concentration at a fixed osmolality of 300 mOs mol/kg. The lower the spectrin density, the smaller the deformability index (DI) values, surface-to-volume ratio, ...