Chromosome instability usually leads to tumorigenesis. Bloom syndrome (BS) is a genetic disease associated with chromosome instability. The BS gene product, BLM, has been reported to function in the spindle assembly checkpoint (SAC) to prevent chromosome instability.
Flight time from Detroit to Chicago is usually between 45 minutes to one hour.
Detroit Metropolitan International Airport (DTW) is only 20 miles from Ann Arbor, about a 45 minute drive (at the most). Remember though, the airlines suggest arriving at least 2 hours before your flight! Major hubs are: Delta, Spirit, and US Air among others.