Some molecules or particles are too large or too hydrophilic to pass through a lipid bilayer. Other molecules could pass through the bilayer but must be transported rapidly in such large numbers that channel-type transport is impractical.
Vanna White Has the World's Most G-Rated Wardrobe Malfunction on 'Wheel of Fortune'. by 11:56 AM PST, December 11, 2015. Playing Vanna White Has the World's Most G-Rated Wardrobe Malfunction on 'Wheel of Fortune'. Vanna White found herself in a sticky situation during Thursday's Wheel of Fortune. While walking across the stage, the hostess, unbeknownst to her, brought part of the set with her when a prop gift got caught on the bottom of her dress.
The object was to spin a wheel to win money to spend on great prizes! Notwithstanding the pilot, the original host of Wheel of Fortune was Chuck Woolery, and the original letter turner was Susan Stafford. Charlie O'Donnell was the original announcer. Pat Sajak and Vanna White were nowhere to be found.