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What does Lip twitching mean? This means that you are having a sudden involuntary contraction of your lip muscles. It is also called lip fasciculations. It is something that can happen to anyone regardless of age, race, or gender and is a very common occurrence. It can affect your top, bottom, or both lips.
Lip twitching, in most cases, may be a symptom of fatigue or stress. But the same may also indicate severe underlying medical conditions in the body. Advertisement. Twitching lip, also known as. is caused due to abnormal and irregular contractions of the muscle fibers present in the area around lips. This contraction is involuntary and can also occur due to irritation, injury or stimulation of the nerve endings present in the muscles of the lips.