Chromosome instability usually leads to tumorigenesis. Bloom syndrome (BS) is a genetic disease associated with chromosome instability. The BS gene product, BLM, has been reported to function in the spindle assembly checkpoint (SAC) to prevent chromosome instability.
Flight time from Detroit to Chicago is usually between 45 minutes to one hour.
The total flight duration from Chicago, IL to Mumbai, India is 16 hours, 37 minutes. This assumes an average flight speed for a commercial airliner of 500 mph, which is equivalent to 805 km/h or 434 knots.