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In addition, some studies found that two or more cups of coffee a day can increase the risk of heart disease in people with a specific â and fairly common â genetic mutation that slows the breakdown of caffeine in the body. So, how quickly you metabolize coffee may affect your health risk.
Drinking large amounts of coffee can cause a spike in blood pressure and heart rate. Studies have suggested that coffee increases heart rate, thanks to caffeine's impact on hormones and neurotransmitters. But drinking coffee in moderationâone to three cups per dayâshouldn't have a noticeable impact on a healthy adult.