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The most common cause of intrauterine growth restriction is an abnormality in the placenta. A placental abnormality can cause intrauterine growth restriction because the fetus may become malnourished.Some other potential causes include: 1  Congenital or chromosomal abnormalities. 2  Heart disease.3  Diabetes.he most common cause of intrauterine growth restriction is an abnormality in the placenta. A placental abnormality can cause intrauterine growth restriction because the fetus may become malnourished. Some other potential causes include: 1  Congenital or chromosomal abnormalities. 2  Heart disease. 3  Diabetes.
See also: Birth weight. There is much variation in the growth of the human fetus. When fetal size is less than expected, that condition is known as intrauterine growth restriction (IUGR) also called fetal growth restriction (FGR); factors affecting fetal growth can be maternal, placental, or fetal.