Cholesterol, particularly one type of cholesterol called LDL (bad) cholesterol, seeps into the inner walls of the arteries, creating plaque. Like sores on your skin, plaques are raw, sensitive to infection, which means they make the inside skin of the arteries a breeding ground for inflammation.
Frasier Crane. Frasier Winslow Crane is a fictional character on the American television sitcoms Cheers and Frasier, portrayed by Kelsey Grammer. Grammer received award recognitions for portraying this character in these two shows, in addition to a 1992 one-time appearance in Wings.
Since 2007 she has appeared in many episodes of The Big Bang Theory on CBS as Leslie Winkle, a scientist friend (with benefits) to the character played by Johnny Galecki, who also portrayed her longtime boyfriend and husband David Healy on Roseanne.