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Other things that may lead to vitamin K deficiency include: 1  Health problems that can prevent your body from absorbing vitamin K, such as gallbladder or biliary disease, cystic fibrosis, celiac disease, and Crohn's disease. 2  Liver disease. 3  Taking blood thinners, such as warfarin (Coumadin). 4  Long-term hemodialysis. 5  Serious burns.
Vitamin K (VK) deficiency can occur in any age group but is encountered most often in infancy. VK, an essential, lipid-soluble vitamin that plays a vital role in the production of coagulation proteins, is found in green, leafy vegetables and in oils, such as soybean, cottonseed, canola, and olive oils.VK is also synthesized by colonic bacteria.(See Etiology and Epidemiology.).arious drugs, such as cholestyramine, bind to bile acids, thus preventing fat-soluble vitamin absorption. Coumadin blocks the effect of VK epoxide reductase and VK reductase, thereby inducing an intracellular deficiency.