Chromosome instability usually leads to tumorigenesis. Bloom syndrome (BS) is a genetic disease associated with chromosome instability. The BS gene product, BLM, has been reported to function in the spindle assembly checkpoint (SAC) to prevent chromosome instability.
Flight time from Detroit to Chicago is usually between 45 minutes to one hour.
If you include this extra time on the tarmac, the average total elapsed time from gate to gate flying from Chicago, IL to Tampa Bay is 2 hours, 26 minutes.