duete; see due, ty 2 ]. syn: duty, obligation refer to something a person feels bound to do. A duty often applies to what a person performs in fulfillment of the permanent dictates of conscience, piety, right, or law: one's duty to tell the truth; a parent's duty to raise children properly.
Mutations in the RB1 gene are responsible for most cases of retinoblastoma. RB1 is a tumor suppressor gene, which means that it normally regulates cell growth and keeps cells from dividing too rapidly or in an uncontrolled way.
Symptoms of Retinoblastoma. In many cases, signs and symptoms of retinoblastoma include such things as crossed eyes, a condition called white eye, and pain or redness in the eye. Other symptoms sometimes seen with the cancer can include blurry vision and a pupil that appears enlarged.