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Venereal disease: A disease that is contracted and transmitted by sexual contact, caused by microorganisms that survive on the skin or mucus membranes, or that are transmitted via semen, vaginal secretions, or blood during intercourse.he genital areas provide a moist, warm environment that is especially conducive to the proliferation of bacteria, viruses, and yeasts, so a great many diseases can be transmitted this way, including AIDS, chlamydia, genital warts, gonorrhea, syphilis, yeast infections, and some forms of hepatitis.
Sexually transmitted infections (STIs) are also commonly referred to as venereal disease, and are some of the most common diseases that you can get from another person through sexual contact. With more than 20 STIs in existence, they affect more than 110 million men and women in the United States.