Origin of GLIRIDAE. New Latin, from Glir-, Glis, type genus + -idae. This word doesn't usually appear in our free dictionary, but the definition from our premium Unabridged Dictionary is offered here on a limited basis.Note that some information is displayed differently in the Unabridged.rigin of GLIRIDAE. New Latin, from Glir-, Glis, type genus + -idae. This word doesn't usually appear in our free dictionary, but the definition from our premium Unabridged Dictionary is offered here on a limited basis.
knockout mouse(Noun) Any of several forms of mice that have been genetically engineered by inactivating specific genes. Knockout mouse. A knockout mouse is a genetically engineered mouse in which researchers have inactivated, or knocked out, an existing gene by replacing it or disrupting it with an artificial piece of DNA.
Knockouts are used to define the overall requirement for a gene and to model loss of function mutations. Knockins introduce heterologous coding sequences such as reporters or DNA recombinases, or to incorporate changes in DNA sequence to humanize a mouse gene or to generate point mutations.lternatively, DNA from C57BL/6J BAC genomic clones can be used to construct targeting vectors for a 129 ES cell line if there are no polymorphisms in the region of the gene between C57BL/6J and 129S1/SvImJ strains of mice.