Chromosome instability usually leads to tumorigenesis. Bloom syndrome (BS) is a genetic disease associated with chromosome instability. The BS gene product, BLM, has been reported to function in the spindle assembly checkpoint (SAC) to prevent chromosome instability.
Flight time from Detroit to Chicago is usually between 45 minutes to one hour.
Travel thoughts for your from Toledo to Chicago. Driving By Car: If you were in a car and maintained an average speed of 60mph (96 kmh) over the course of your it would take you around 4.17 hours to get from Toledo to Chicago. We've included a few additional estimates below based on different average speeds.