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FOLFOX is a chemotherapy regimen for treatment of colorectal cancer, made up of the drugs.
In the stage II subgroup of the MosaÃ¯c trial, the benefit for stage II is 3.5% with FOLFOX, reaching 5.2% in high-risk stage II as compared to 5-FU/LV. According to Moertel et al., IMPACT and QUASAR1, 73â77% of stage II patients are cured with surgery alone at 3.5â5 years.