First are dose-response studies. The dose of trazodone needed to induce and maintain sleep is not well understood. Thus, clinicians use anywhere from 25 mg to 150 mg taken at bedtime as a hypnotic dose. This is a critical question because it is recognized that at high doses these medications carry a high safety risk.
Ceruminous gland tumors arise in the external auditory canal (EAC) from specialized glands that are closely related to apocrine glands,which are found in the axillae, anogenital area, areolae, and eyelids (glands of Moll).
1 Adenocarcinomas are most frequently found in the minor salivary glands of the nose and paranasal sinuses. 2  They do, however, account for 15 percent of malignancies of the parotid and 10% of malignancies of the submandibular glands.