Side Effects. Side effects are rare; still symptoms like ear irritation, acute inflammation of the ear canal and pinna are reported. In some cases the pet might experience lack of appetite, vomiting, diarrhea, or hearing loss during the course of treatment, which might require immediate medical aid.
Furthermore, if the median age of a marathon participant is about 40, then the average maximum heart rate of a U.S. marathoner is about 180. Seventy percent of 180 is 126, while 80 percent is 144. Therefore, the heart rate of a mid-pack runner during a marathon is near the middle of the range -- between 126 and 144, or 135 beats per minute.
Among women runners, the median finishing time was 4:42:53. Not surprisingly, the average time it takes to run a marathon increases as you get older. For example, the average for males between 30 and 34 years of age is 4:00:11, while the average for those 50 to 54 years old is 4:23:0.