1 The vast majority of people will never have an anaphylactic reaction. 2  The most common causes of anaphylaxis include drugs, such as penicillin, insect stings, foods (peanuts, shellfish), X-ray dye, and latex. 3  The symptoms of anaphylaxis may vary and can include hives, tongue swelling, vomiting, and even shock.
The recommended starting dose for prolonged-release venlafaxine is 75 mg given once daily. Patients not responding to the initial 75 mg/day dose may benefit from dose increases up to a maximum dose of 375 mg/day. Dosage increases can be made at intervals of 2 weeks or more.
In this study, 80 postmenopausal women with hot flushes (more than 14 per week) were randomized to receive either treatment with venlafaxine XR (n=40) or placebo (n=40). Venlafaxine was initiated at 37.5 mg daily for 1 week and then increased to 75 mg daily for the remainder of the study period. Subjects kept daily hot flush diaries indicating frequency and severity of their hot flushes.