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PRESCRIBED FOR: Extended release guanfacine (Intuniv) is used alone or in combination with other medications for the treatment of ADHD. Immediate release guanfacine (Tenex) is used alone or in combination with other medications for the treatment of high blood pressure.enex is used alone or in combination with other medications for the treatment of hypertension (high blood pressure). Guanfacine reduces blood pressure by reducing the resistance of blood flow in the blood vessels, and by decreasing heart rate.