In the US, codeine is a controlled substance that can only be administered by prescription. Actually your answer is not correct. Cough â¦syrup containing codeine can be purchased from a pharmacist and siging a log book. I am a Pharmacist and at least in Tennessee this is legal.
Aromatase inhibitor: A drug that inhibits the enzyme aromatase and by that means lowers the level of the estrogen estradiol. Aromatase inhibitors represent a class of antiestrogens. Aromatase catalyzes the conversion of testosterone (an androgen) to estradiol (an estrogen) in many tissues including the adrenal glands, ovaries, placenta, testicles, adipose (fat) tissue, and brain. Estrogen is produced directly by the ovaries and is also made by the body using aromatase. Aromatase inhibitors cannot do anything about estrogen produced by the ovaries, but they do interfere with the body's use of aromatase. The growth of many breast cancers is promoted by estrogens.
The new non-steroidal and steroidal aromatase inhibitors are at least as effective as megestrol acetate (MA) as second-line hormonal agents in postmenopausal women with breast cancer.However, they are superior to MA in terms of tolerability and adverse effects.he Type I inhibitors have a steroidal structure similar to androgens and inactivate the enzyme irreversibly by blocking the substrate-binding site, and are therefore known as aromatase inactivators. Examples of such drugs include formestane and exemestane (Aromasin).