The company will, however, deduct the policy excess. Letâs say your car is worth Â£10,000 and is written-off in an accident. The insurance company might offer a settlement of Â£10,000, less the excess of Â£300, to give you Â£9,700.
It is now generally accepted that the demyelination seen in MS is caused by an abnormal immune process â that is, by activation of T cells (and perhaps B cells) against some component of central nervous system myelin (the fatty sheath that surrounds and insulates nerve fibers).
However, magnetic resonance imaging has shown that when a person is undergoing an MS attack, the bloodâbrain barrier has broken down in a section of the brain or spinal cord, allowing white blood cells called T lymphocytes to cross over and attack the myelin.t is believed that latent HIV can cross the bloodâbrain barrier inside circulating monocytes in the bloodstream ( Trojan horse theory) within the first 14 days of infection. Once inside, these monocytes become activated and are transformed into macrophages.