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Assessment of Depression in Advanced Illness. What Symptoms to Look for and How to Assess. Somatic symptoms (e.g., changes in appetite, weight, energy level, libido, or sleeping) are almost invariably present in patients with advanced illness.
Some of these symptoms -- fatigue, irritability, weight changes, and sleep problems -- are symptoms that may also indicate depression. Your doctor may order blood tests to determine levels of certain hormones, including: 1  thyroid stimulating hormone (TSH, which is released by the pituitary gland)  triiodothyronine (T3)