/day, 10 mg/day, 15 mg/day and 20 mg/day, the efficacy of Trintellix for the acute treatment of MDD was demonstrated in at least one of the clinical studies as measured by improvement in the primary efficacy endpoint.
Hydrogen bonding is important in many chemical processes. Hydrogen bonding is responsible for water's unique solvent capabilities. Hydrogen bonds hold complementary strands of DNA together, and they are responsible for determining the three-dimensional structure of folded proteins including enzymes and antibodies. simple way to explain hydrogen bonds is with water. The water molecule consists of two hydrogens covalently bound to an oxygen. Since oxygen is more electronegative than hydrogen, oxygen pulls the shared electrons more closely to itself.
Hydrogen bonds are primarily formed between molecules as an electrostatic attractions. Hydrogen bonding is the key to water's unique properties as a universal medium. Hydrogen bonds can also form between parts of the same molecule, giving it increase stability. The shape of DNA and large proteins, for example, is maintained by hydrogen bonds within the molecule. general equation for synthesis