Cases of severe hepatotoxicity, including hepatic necrosis, life-threatening hepatic failure, and fatal events, have been reported with Cipro XR. Acute liver injury is rapid in onset (range 1â39 days), and is often associated with hypersensitivity. The pattern of injury can be hepatocellular, cholestatic or mixed.
The Dolomites are a part of the mountain range of the Italian Alps. They are mostly spread in the province of Belluno and to a lesser degree in the provinces of Trento and Bolzano-Bozen, all of which are located in north eastern part of Italy.
Lastly, the Eastern Alps run west to east from the Brenner Pass to Trieste and include the Dolomites (Dolomiti; see ) and Mount Marmolada (10,968 ft [3,343 m]). The Italian foothills of the Alps, which reach no higher than 8,200 ft (2,500 m), lie between these great ranges and the Po valley.