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Biochemistry of Dog Coat Color. The color of a dogâs coat is determined by relative levels of two pigments: eumelanin, which can be either brown or black, and pheomelanin, which is yellow to orange or red. Both pigments are generated by metabolism of tyrosine. A schematic diagram of the pathway is below. Schematic of the melanin synthesis pathways.
All dogs exhibiting the Brindle striping pattern on a base color of any yellow-red-black (which may appear shaded) pigment are identifiable as this color. The base color descriptor is not significant from a genetic identification viewpoint and is not necessary as an AKC coat color identifier. The Brindle and White (059) color identifier should be circled on the blue slip. When appropriate, a Markings identifier is used on the blue slip.