Manufacturers have succeeded in selling this technology by emphasizing its energy efficiency and other benefits. The installed cost of VRF systems is about $18 per square foot of conditioned space, while a conventional air-source heat pump system costs about $12 to $15 per square foot.anufacturers have succeeded in selling this technology by emphasizing its energy efficiency and other benefits. The installed cost of VRF systems is about $18 per square foot of conditioned space, while a conventional air-source heat pump system costs about $12 to $15 per square foot.
Essential Thrombocythemia. Essential thrombocythemia (ET) is a type of blood cancer known as a myeloproliferative neoplasm. It involves the abnormal development and function of bone marrow cells that produce blood cells, and leads to the overproduction of blood cells known as platelets.
The exact cause of essential thrombocythemia and similar conditions, known as myeloproliferative disorders, isn't known. About 80 percent of people with the disorder have an acquired gene mutation contributing to the disease.This may involve the Janus kinase 2 (JAK2), calreticulin (CALR) or MPL gene mutation. normal platelet count ranges from 150,000 to 450,000 platelets per microliter of blood. If you have essential, or primary, thrombocythemia, your bone marrow makes too many platelet-forming cells (megakaryocytes).