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Myopathy is a disease of muscle in which the muscle fibers do not function properly. This results in muscular weakness. Myopathy simply means muscle disease (Greek myo- muscle + patheia < -pathy suffering). This meaning implies that the primary defect is within the muscle, as opposed to the nerves (neuropathies or neurogenic disorders) or elsewhere (e.g., the brain).
Mitochondrial myopathy: A group of neuromuscular diseases caused by damage to the mitochondria, energy-producing structures in cells that serve as power plants. Nerve and muscle cells require a great deal of energy and are particularly impaired by mitochondrial dysfunction.