Akt Signaling. Akt (v-Akt Murine Thymoma Viral Oncogene)/ PKB (Protein Kinase-B) is a Serine/threonine Kinase that is involved in mediating various biological responses, such as inhibition of Apoptosis and stimulation of cell proliferation. Three mammalian isoforms are currently known: Akt1/PKB- Alpha, Akt2/PKB-Beta and Akt3/PKB-Gamma.
Vascular: Relating to blood vessels. For example, the vascular system in the body includes all of the veins and arteries. And, a vascular surgeon is an expert at evaluating and treating problems of the veins and arteries.
Vascular disease is disease of the blood vessels (arteries. and veins). A common and serious form of vascular. disease (coronary artery disease) affects the arteries that. give oxygen to the heart muscle. Peripheral vascular. disease (PVD) affects the areas that are âperipheralâ. (outside) your heart.