Aminoglycosides are excreted by glomerular filtration and have a serum half-life of 2 to 3 h; the half-life increases exponentially as the GFR falls (eg, in renal insufficiency, in the elderly).
Madagascar is the world's major natural vanilla producer, accounting for about 75% of production. Cloves are the third main export crop, grown mostly by smallholders. Production follows a 4-year cycle with 2â3 years of high output followed by one year of low production.
Madagascar cuisine also has specialty dishes, such as romazava, sesika, khimo and kabaro. Romazava is a beef stew, and sesika is a blood sausage made from poultry. khimo is curried ground beef and kabaro is lima beans with curry. The people of Madagascar like to serve food that is not very spicy, but they do have a hot chili relish called sakay.