On December 20, 2017, the Food and Drug Administration granted regular approval to the anti-PD1 monoclonal antibody, nivolumab (OPDIVO, Bristol-Myers Squibb Company) for the adjuvant treatment of patients with melanoma with involvement of lymph nodes or in patients with metastatic disease who have undergone complete resection.
Given the right environment, the worms will go to work to digest the kitchen scraps and bedding faster than any other compost method. In about 3-4 months, the worms will have digested nearly all the garbage and bedding and the bin will be filled with a rich, black natural fertilizer and soil amendment.
After 3-5 months, when your bin is filled with compost (and very little bedding), it is time to harvest the bin. Harvesting means removing the finished compost from the bin. After several months, worms need to be separated from their castings which, at high concentrations, create an unhealthy environment for them.