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Qui tam action. Definition. In a qui tam action, a private party called a relator brings an action on the government's behalf. The government, not the relator, is considered the real plaintiff. If the government succeeds, the relator receives a share of the award. Also called a popular action.
Mechanism [edit]. Like all other class I antiarrhythmic agents, quinidine primarily works by blocking the fast inward sodium current (I Na). Quinidine's effect on I Na is known as a 'use dependent block'. This means at higher heart rates, the block increases, while at lower heart rates, the block decreases. The effect of blocking the fast inward sodium current causes the phase 0 depolarization of the cardiac action potential to decrease (decreased V max).