Sertraline should not be taken with or within two weeks of taking monoamine oxidase inhibitors (MAOIs). These include phenelzine (NardilÂ®), tranylcypromine (ParnateÂ®), isocarboxazid (MarplanÂ®), rasagiline (AzilectÂ®), and selegiline (EmsamÂ®).
Pure caffeine is a white, tasteless substance that makes up as much as 5% of. the weight of tea leaves. By structure, caffeine is closely related to the purine bases, guanine and adenine, found in deoxyribonucleic acids (DNA).
Caffeine was discovered in 1819 by Friedlieb Runge. Runge was given a box of Arabian mocha beans by Johann Wolfgang von Goethe. Goethe asked Runge to analyze the beans. It was from this sample that Runge isolated the world's first sample of pure caffeine.