Akt Signaling. Akt (v-Akt Murine Thymoma Viral Oncogene)/ PKB (Protein Kinase-B) is a Serine/threonine Kinase that is involved in mediating various biological responses, such as inhibition of Apoptosis and stimulation of cell proliferation. Three mammalian isoforms are currently known: Akt1/PKB- Alpha, Akt2/PKB-Beta and Akt3/PKB-Gamma.
Vascular: Relating to blood vessels. For example, the vascular system in the body includes all of the veins and arteries. And, a vascular surgeon is an expert at evaluating and treating problems of the veins and arteries.
Historical Examples. 1  Vascular: relating to the blood-vessels or circulatory system. 2  These are successively injected into the circulatory system. 3  There is no circulatory system, nor are there any special organs of respiration. 4  A similar difference, quite on a par with this, exists in the circulatory system.