Per general etiquette, the mother of the bride buys her wedding day outfit first, then notifies the mother of the groom about the color, length and overall formality of her choice. But if the groom's mom doesn't get word by the four-month mark, she should touch base with the bride-to-be about what to do.
Genetics. The two main types of hemophilia are caused by gene mutations that affect the levels of clotting factors in the blood. Mutation of the FVIII gene leads to hemophilia A, also called classic hemophilia, while a mutations in the FIX gene leads to hemophilia B, also called Christmas disease.
1 Hemophilia A, a blood clotting disorder caused by a mutation of the Factor VIII gene and leading to a deficiency of Factor VIII. 2  It was once thought to be the royal disease found in the descendants of Queen Victoria. 3  This is now known to have been Hemophilia B (see below).he most common X-linked recessive disorders are: 1  Red-green color blindness, a very common trait in humans and frequently used to explain X-linked disorders. 2  Between seven and ten percent of men and 0.49% to 1% of women are affected.