Maraviroc is an entry inhibitor. Specifically, maraviroc is a negative allosteric modulator of the CCR5 receptor, which is found on the surface of certain human cells. The chemokine receptor CCR5 is an essential co-receptor for most HIV strains and necessary for the entry process of the virus into the host cell.
January 14, 1742. Greenwich, England. Edmond Halley, Edmond also spelled Edmund (born Nov. 8, 1656, Haggerston, Shoreditch, near Londonâdied Jan. 14, 1742, Greenwich, near London) English astronomer and mathematician who was the first to calculate the orbit of a comet later named after him.
The next predicted perihelion of Halley's Comet is 28 July 2061, when it is expected to be better positioned for observation than during the 1985â1986 apparition, as it will be on the same side of the Sun as Earth. It is expected to have an apparent magnitude of â0.3, compared with only +2.1 for the 1986 apparition.