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1 Squalene is a component of some adjuvants that are added to vaccines to enhance the immune response. 2  MF59, an adjuvant produced by Novartis and added to the FLUAD flu vaccine, is such an example. 3  Squalene by itself is not an adjuvant, but emulsions of squalene with surfactants do enhance the immune response.hat is squalene? 1  Squalene is a naturally occurring substance found in plants, animals, and humans. 2  Squalene is also found in a variety of foods, cosmetics, over-the-counter medications, and health supplements. 3  Squalene is commercially extracted from fish oil, and in particular shark liver oil.
Squalene is a natural 30-carbon organic compound originally obtained for commercial purposes primarily from shark liver oil (hence its name), although plant sources (primarily vegetable oils) are now used as well, including amaranth seed, rice bran, wheat germ, and olives.qualene is used in cosmetics, and more recently as an immunologic adjuvant in vaccines. Squalene has been proposed to be an important part of the Mediterranean diet as it may be a chemopreventive substance that protects people from cancer.