The insulin receptor (IR) is a transmembrane receptor that is activated by insulin, IGF-I, IGF-II and belongs to the large class of tyrosine kinase receptors.ffect of insulin on glucose uptake and metabolism. Insulin binds to its receptor (1), which, in turn, starts many protein activation cascades (2). These include: translocation of Glut-4 transporter to the plasma membrane and influx of glucose (3), glycogen synthesis (4), glycolysis (5), and fatty acid synthesis (6).
Litchfield, Illinois. For other places with the same name, see Litchfield (disambiguation). Litchfield is a city in Montgomery County, Illinois, United States. The population was 6,939 at the 2010 census, and 6,588 in 2009 and 7,012 in 2015. It is located in south central Illinois, south of Springfield and northeast of Metro-East.
Litchfield County was created on October 9, 1751, by an act of the Connecticut General Court from land belonging to Fairfield, New Haven, and Hartford counties.