Leroy Satchel Paige was the longtime Negro League star who eventually received his due in the majors. He reportedly got his nickname working as a baggage porter in Mobile, Ala., where he became a satchel tree by carrying several bags at once. Satchel, the man, was literally ageless.
The diagnosis of AML requires the identification of 20% or more leukemic blasts in the bone marrow. Further analysis then must separate AML from acute lymphoblastic leukemia by showing evidence for commitment to the myeloid lineage.
The treatment and prognosis of AML differ from those of chronic myelogenous leukemia (CML) in part because the cellular differentiation is not the same; AML involves higher percentages of dedifferentiated and undifferentiated cells, including more blasts (myeloblasts, monoblasts, and megakaryoblasts).