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In general, whenever the diagnosis of meningitis is strongly considered, a lumbar puncture should be promptly performed. Examination of the cerebrospinal fluid (CSF) is the cornerstone of the diagnosis. The diagnosis of bacterial meningitis is made by culture of the CSF sample.
Lumbar puncture is the most important lab test for meningitis. It is also called a spinal tap. A sample of fluid is removed from around the spine and tested to see if it contains organisms that cause the illness. Your doctor may also order other tests, such as blood tests, a CT scan, or an MRI.