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1 Artificial Sweeteners Artificial sweeteners and sugar alcohols, particularly mannitol and sorbitol, can cause diarrhea in some people. 2  Mannitol and sorbitol linger in the stomach, Schiller says, which can result in bloating and diarrhea.
It has been suggested that the use of artificial sweeteners may have a stimulating effect on appetite and, therefore, may play a role in weight gain and obesity. However, research into sweeteners and appetite stimulation is inconsistent.ietitian Emma Carder states: âResearch into sweeteners shows they are perfectly safe to eat or drink on a daily basis as part of a healthy diet.â. She also says they are a really useful alternative for people with diabetes who need to watch their blood sugar levels while still enjoying their favourite foods.