Meaning to close by folding or bringing together is from mid-14c. Sense of to set (someone) free (from) (c.1500) is obsolete except in dialectal phrases such as to get shut of. Colloquial shut-eye for sleep is from 1899. To shut (one's) mouth desist from speaking is recorded from 1340.
Medical Device Regulation Act. Medical Device Amendments of 1976. An Act to amend the Federal Food, Drug, and Cosmetic Act to provide for the safety and effectiveness of medical devices intended for human use, and for other purposes. Enacted by.
FDA Panel Torn on Watchman Device. Calls the device safe, but splits on its efficacy. GAITHERSBURG, Md. -- An FDA advisory committee struggling with limits of the regulatory process delivered a split vote Wednesday along with a nuanced recommendation -- once again leaving the Watchman left atrial appendage closure device's future in serious doubt.