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Prednisone is prescribed for a client with diabetes mellitus who is taking Humulin NPH insulin daily. Which prescription change does the nurse anticipate during therapy with the prednisone? a) An additional dose of prednisone daily b) A decreased amount of daily Humulin NPH insulin c) An increased amount of daily Humulin NPH insulin d) The addition of an oral hypoglycemic medication daily Pharmacology NCLEX Practice Questions Answers and Rationale 31) C
NPH insulin (Neutral Protamine Hagedorn also known as Humulin N, Novolin N among others) is an intermediate-acting insulin given to help control the blood sugar level of those with diabetes. NPH was created in 1936 when Nordisk formulated isophane porcine insulin by adding neutral protamine to regular insulin.NPH stands for neutral protamine Hagedorn. This is a suspension of crystalline zinc insulin combined with the positively charged polypeptide, protamine.PH was created in 1936 when Nordisk formulated isophane porcine insulin by adding neutral protamine to regular insulin.