Leroy Satchel Paige was the longtime Negro League star who eventually received his due in the majors. He reportedly got his nickname working as a baggage porter in Mobile, Ala., where he became a satchel tree by carrying several bags at once. Satchel, the man, was literally ageless.
The diagnosis of AML requires the identification of 20% or more leukemic blasts in the bone marrow. Further analysis then must separate AML from acute lymphoblastic leukemia by showing evidence for commitment to the myeloid lineage.
This definition is not supported by biological evidence and is therefore arbitrary. The more recent WHO definition proposes a blast count of 20% in analogy to the definition of AML. This is, however, also arbitrary without any biological evidence. It has been shown that a change of definition, e.g. to a blast count of 20%, would regroup up to 10% of patients.