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Assessment of Depression in Advanced Illness. What Symptoms to Look for and How to Assess. Somatic symptoms (e.g., changes in appetite, weight, energy level, libido, or sleeping) are almost invariably present in patients with advanced illness.
1 In some cases, depression may be linked to an underlying physical health problem. 2  Lab tests. 3  For example, your doctor may do a blood test called a complete blood count or test your thyroid to make sure it's functioning properly.