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A larger peak in activity at around 6 hours is usually associated with a shorter action time, and vice versa. Anyone who does not take their long-acting insulin at about the same time each day can also experience gaps and stacking of insulin with a single injection a day. Smaller doses are also often associated with greater insulin activity at 6 hours with less at 18 hours and beyond.
They digest and absorb into the bloodstream quickly, resulting in a blood sugar peak in 30-60 minutes. For these types of foods, it is best to give your mealtime insulin bolus 15-30 minutes prior to eating. This will allow the insulin peak to coincide as closely as possible with the blood sugar peak. And that, of course, will produce the best possible after-meal control.