In humans (n = 10) infused with 1.0â1.3 mmol sodium dl-lactate/(kg Â· h), â¼90% of d-lactate was metabolized, and 10% excreted in the urine (12). At higher infusion rates of 3.0â4.6 mmol/(kg Â· h), metabolism decreased to â¼75% of overall clearance (12).
Deaths from alcohol poisoning as a contributing cause peaked for those between ages 35 and 44 (average age at death was 39.9 years). When the age-specific rate was calculated using deaths with any mention of alcohol poisoning, the rate was highest at ages 35 to 44 (1.33 deaths per 100,000 population).
Approximately 2.5 million people die each year from alcohol related causes, the WHO said in its Global Status Report on Alcohol and Health.. The harmful use of alcohol is especially fatal for younger age groups and alcohol is the world's leading risk factor for death among males aged 15-59, the report found. In Russia and the Commonwealth of Independent States (CIS), every fifth death is due to harmful drinking, the highest rate.