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1 Artificial Sweeteners Artificial sweeteners and sugar alcohols, particularly mannitol and sorbitol, can cause diarrhea in some people. 2  Mannitol and sorbitol linger in the stomach, Schiller says, which can result in bloating and diarrhea.
The high-fructose corn syrup in coke can cause diarrhea. Photo Credit tiverylucky/iStock/Getty Images. If you frequently suffer from diarrhea within a few hours of drinking Coke or other types of soft drinks, it may be due to one of the ingredients these beverages contain.