Furthermore, the protestant John Knox and Mary of Guise's half-brother James Stuart were stirring Scotland up against the Church of Rome, a situation which the King of France could not allow to continue. Thus Henry I gave his consent and the public marriage document was signed on 19th April 1558.
Critical Limb Ischemia (CLI) Critical Limb Ischemia (CLI) is a severe obstruction of the arteries which markedly reduces blood flow to the extremities (hands, feet and legs) and has progressed to the point of severe pain and even skin ulcers or sores. The pain caused by CLI can wake up an individual at night.
Surgical methods of revascularization for claudication and chronic limb ischemia are, traditionally, profundoplasty and femorodistal bypass grafting. springer Seventy patients with limb-threatening ischemia because of multilevel, lower extremity arterial occlusive disease were treated with aortofemoral reconstruction and extended profundoplasty.