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Cowden syndrome is a disorder characterized by multiple noncancerous, tumor-like growths called hamartomas and an increased risk of developing certain cancers. Almost everyone with Cowden syndrome develops hamartomas.
Leaky gut syndrome (also known as intestinal hyperpermeability), is the result of a compromise to the intestinal lining. During the normal digestion process the tight junctions (think of them as protective gates) stay closed, forcing all molecules to effectively be screened and only pass into the blood stream through the mucosal cells.