Introduction [edit]. A carboxyl group consists of a carbon double-bonded to an oxygen and also bonded to a-OH group. Compounds with carboxyl groups are called carboxylic acids or organic acids. The carboxyl group can act as an acid when by donating a proton (H +) to a solution and becoming ionized.
It therefore makes perfect sense to use the bronchodilator first, wait a few minutes, and then to use the steroid inhaler, after the airways have been opened up and are more relaxed. This way, the steroid can penetrate the lungs more effectively, and get down to decrease inflammation in your smaller airways.
1 If more puffs are prescribed, the ideal is to wait between doses.  For bronchodilators that are short-acting beta agonists, it is best to wait 3 to 5 minutes. These fast-acting inhalers begin to open your airways quickly. When you wait after your first dose, the next doses can go deeper into your lungs. See âHow to Sequence Inhalersâ .