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1 Artificial Sweeteners Artificial sweeteners and sugar alcohols, particularly mannitol and sorbitol, can cause diarrhea in some people. 2  Mannitol and sorbitol linger in the stomach, Schiller says, which can result in bloating and diarrhea.
A 2005 study by the University of Texas Health Science Center at San Antonio showed that increased weight gain and obesity was associated with increased use of diet soda in a population based study. Animal studies have indicated that artificial sweeteners can cause body weight gain.