Melania Trump. Melania Trump (born Melanija Knavs [mÉËlaËnija ËknaËuÌ¯s], April 26, 1970; Germanized to Melania Knauss) is the First Lady of the United States, married to President Donald Trump.
Rectal administration uses the rectum as a route of administration for medication and other fluids, which are absorbed by the rectum's blood vessels, and flow into the body's circulatory system, which distributes the drug to the body's organs and bodily systems.n addition, the rectal route bypasses around two thirds of the first-pass metabolism as the rectum's venous drainage is two thirds systemic (middle and inferior rectal vein) and one third portal (superior rectal vein).
6.4 Administering Medications Rectally and Vaginally. Medication Administered Rectally. The rectal route (see Figure 6.1) is not as reliable in absorption and distribution as oral and parenteral routes. The rectal route is, however, relatively safe because there is less potential for adverse effects (Perry et al., 2014). Rectal medications are given for their local effects in the gastrointestinal system (e.g., laxatives) or their systemic effects (e.g., analgesics when oral route is contraindicated).