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Caffeine withdrawal symptoms typically appear 12 to 24 hours after abstaining from coffee, and peak within 24 to 48 hours. They include: headache; lethargy and drowsiness; depressed mood; anxiety; nausea; vomiting; muscle pain and stiffness; and inability to concentrate.
Top 15 Caffeine Withdrawal Symptoms. 1  Headache. A caffeine headache usually starts behind the eyes and then moves up the front of the head. 2  Sleepiness. This just isnât your normal tiredness, this is sitting up straight but still canât keep your eyes open tiredness. 3  Irritability. Everyone and everything gets on your last nerve.  Lethargy.