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Prednisone is prescribed for a client with diabetes mellitus who is taking Humulin NPH insulin daily. Which prescription change does the nurse anticipate during therapy with the prednisone? a) An additional dose of prednisone daily b) A decreased amount of daily Humulin NPH insulin c) An increased amount of daily Humulin NPH insulin d) The addition of an oral hypoglycemic medication daily Pharmacology NCLEX Practice Questions Answers and Rationale 31) C
NPH insulin is an insulin with an intermediate-duration of action. It has an onset of action about 2 hours following administration and a duration of action of 18 to 26 hours. Its maximal effect is 4 to 12 hours after administration. person with this type of diabetes must inject exogenous insulin (insulin from sources outside the body). In type II diabetes, the beta cells produce insulin, but cells throughout the body do not respond normally to it.