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Cowden syndrome is a disorder characterized by multiple noncancerous, tumor-like growths called hamartomas and an increased risk of developing certain cancers. Almost everyone with Cowden syndrome develops hamartomas.
The cancerous development starts at 30 to 40 years of age. Cowden syndrome is also cause cancer in kidney and skin. Some typical health related risk factors, like a specific brain tumor clinically termed as Lhermitte-Duclos disease is associated with Cowden syndrome. Lhermitte-Duclos disease is non-cancerous in nature.