Maraviroc is an entry inhibitor. Specifically, maraviroc is a negative allosteric modulator of the CCR5 receptor, which is found on the surface of certain human cells. The chemokine receptor CCR5 is an essential co-receptor for most HIV strains and necessary for the entry process of the virus into the host cell.
January 14, 1742. Greenwich, England. Edmond Halley, Edmond also spelled Edmund (born Nov. 8, 1656, Haggerston, Shoreditch, near Londonâdied Jan. 14, 1742, Greenwich, near London) English astronomer and mathematician who was the first to calculate the orbit of a comet later named after him.
This image of Comet Halley's nucleus was taken by the Giotto spacecraft during a flyby on March 13, 1986. Scientists estimate that about 10% of the surface was boiling off into space. The stuff that boiled off Halley in 1986 may one day be seen again during an Orionid meteor shower.