First are dose-response studies. The dose of trazodone needed to induce and maintain sleep is not well understood. Thus, clinicians use anywhere from 25 mg to 150 mg taken at bedtime as a hypnotic dose. This is a critical question because it is recognized that at high doses these medications carry a high safety risk.
Ceruminous gland tumors arise in the external auditory canal (EAC) from specialized glands that are closely related to apocrine glands,which are found in the axillae, anogenital area, areolae, and eyelids (glands of Moll).
The spinal cord has a cone shaped end which is termed as conus medullaris. It is located between the end points of thoracic vertebrae or T-12 and at the starting of lumbar vertebrae or L-1. Very rarely, it is also located between L-1 and L-2.ometimes constriction or unwanted pressure affects the functioning of nerves located in the conus medullaris. This condition is termed as medullaris syndrome. This external pressure can originate from a tumor or hematoma.