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1 Squalene is a component of some adjuvants that are added to vaccines to enhance the immune response. 2  MF59, an adjuvant produced by Novartis and added to the FLUAD flu vaccine, is such an example. 3  Squalene by itself is not an adjuvant, but emulsions of squalene with surfactants do enhance the immune response.hat is squalene? 1  Squalene is a naturally occurring substance found in plants, animals, and humans. 2  Squalene is also found in a variety of foods, cosmetics, over-the-counter medications, and health supplements. 3  Squalene is commercially extracted from fish oil, and in particular shark liver oil.
Although cholesterol is synthesized from squalene in human body, dietary intake of squalene does not elevate serum cholesterol level. Amounts of squalene present in human tissues vary, being rich in areas which have high sebaceous glands (face, forehead) and low in areas having poor sebaceous glands.