Per general etiquette, the mother of the bride buys her wedding day outfit first, then notifies the mother of the groom about the color, length and overall formality of her choice. But if the groom's mom doesn't get word by the four-month mark, she should touch base with the bride-to-be about what to do.
Genetics. The two main types of hemophilia are caused by gene mutations that affect the levels of clotting factors in the blood. Mutation of the FVIII gene leads to hemophilia A, also called classic hemophilia, while a mutations in the FIX gene leads to hemophilia B, also called Christmas disease.
Causes. When you bleed, your body normally pools blood cells together to form a clot to stop the bleeding. The clotting process is encouraged by certain blood particles (platelets and plasma proteins). Hemophilia occurs when you have a deficiency in one of these clotting factors. Hemophilia is inherited.However, about 30 percent of people with hemophilia have no family history of the disorder. In these people hemophilia is caused by a genetic change (spontaneous mutation). Hemophilia A, the most common type, is caused by insufficient clotting factor VIII. 2  Hemophilia B, the second most common type, is caused by insufficient clotting factor IX. 3  Hemophilia C, in which signs and symptoms are often mild, is caused by insufficient clotting factor XI.