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Caffeine withdrawal symptoms typically appear 12 to 24 hours after abstaining from coffee, and peak within 24 to 48 hours. They include: headache; lethargy and drowsiness; depressed mood; anxiety; nausea; vomiting; muscle pain and stiffness; and inability to concentrate.
The primary symptom of this condition is the presence of blood in the vomit, which may appear as fresh blood, formed clots, or digested blood which resembles coffee grounds. Other symptoms include lack of appetite (anorexia), abdominal pain, and blackish, tar-like feces (melena).