The company will, however, deduct the policy excess. Letâs say your car is worth Â£10,000 and is written-off in an accident. The insurance company might offer a settlement of Â£10,000, less the excess of Â£300, to give you Â£9,700.
It is now generally accepted that the demyelination seen in MS is caused by an abnormal immune process â that is, by activation of T cells (and perhaps B cells) against some component of central nervous system myelin (the fatty sheath that surrounds and insulates nerve fibers).
Primary Cell-Mediated IR. The initial activation of cytotoxic T cells due to. an intracellular pathogen occurs as follows: 1) a dendritic cell or macrophage ingests or is. infected by an intracellular pathogen. 2) peptides fr. pathogen presented on MHC class II. and MHC class I molecules. 3) specific T.