Meaning to close by folding or bringing together is from mid-14c. Sense of to set (someone) free (from) (c.1500) is obsolete except in dialectal phrases such as to get shut of. Colloquial shut-eye for sleep is from 1899. To shut (one's) mouth desist from speaking is recorded from 1340.
Medical Device Regulation Act. Medical Device Amendments of 1976. An Act to amend the Federal Food, Drug, and Cosmetic Act to provide for the safety and effectiveness of medical devices intended for human use, and for other purposes. Enacted by.
After an untested toxic drug called Elixir Sulfanilamide killed 100 people in 15 states in 1937, Congress passed the 1938 Food, Drug and Cosmetic Act. The new act gave the FDA more authority to regulate drugs. Then, the Medical Device Amendments of 1976 gave the agency more regulatory power over medical devices. A common misconception about drug and device approval is that the FDA conducts its own tests before allowing products on the market.