Ono Pharmaceuticals, Opdivo âs originator, has negotiated a price of Â¥150,200 ($1,459) per 20mg vial of Opvido, and Â¥729,849 for 100mg.pplying a similar mark-up to Opdivo, as well as accounting for the higher average body weight of 75kg in the US, gives a price for Opdivo of $118,000 per patient per year, if the same assumption is made about time on therapy.
*Philosophes did not support democracy. -George III of England (r. 1760-1820) and Louis XV of France (r. 1715-1774) had no interest in enlightened monarchy. -Catherine the Great of Russia, Frederick the Great of Prussia, and Joseph II of Austria were Europe's best-known enlightened despots.
1. What were the defining aspects of neoclassical arts? 2. What new form of literature emerged during the 18th century and what were its main characteristics? 3. Why were several rulers in the 18th century Europe known as enlightened despots? 4. What advantages did salons have over earlier ways of spreading ideas? 5. In what way were the enlightened despots less than true reformers? (did they truly change their governments) 6. How did the encyclopedia reflect the Age of Enlightenment? 7. Yellow book 1.