Cell Wall & Gram classification â¢ Most bacteria fall into one of two groups: Gram-positive or Gram-negative â¢ Based on results of a differential staining test (the Gramâs stain) â¢ Primary basis for this distinction is differences in their cell walls Cell Wall: structure & composition Peptidoglycan (murein) â¢ Most importantcomponent
Chlorhexidine is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque. The physiologic effect of chlorhexidine is by means of Decreased Cell Wall Integrity. Chlorhexidine is a biguanide compound used as an antiseptic agent with topical antibacterial activity.
Chlorhexidine has good substantivity (the ability of a mouthwash to bind to hard and soft tissues in the mouth). However, chlorhexidine binds to tannins, meaning that prolonged use in persons who consume coffee, tea or red wine is associated with extrinsic staining (i.e. removable staining) of teeth.