Raynaud's is a fairly rare disorder of the blood vessels supplying the skin. During a Raynaud's attack, the blood vessels narrow, limiting blood circulation to affected areas. It makes parts of your body (usually fingers, toes, nose and ears) feel numb and cool in cold temperatures or under stress.
PPROM is associated with 30-40% of preterm deliveries and is the leading identifiable cause of preterm delivery. PPROM complicates 3% of all pregnancies and occurs in approximately 150,000 pregnancies yearly in the United States.
Preterm PROM predisposes to preterm delivery. PROM at any time increases risk of infection in the woman (chorioamnionitis), neonate (sepsis), or both, as well as risk of abnormal fetal presentation and abruptio placentae. Group B streptococci and Escherichia coli are common causes of infection. Other organisms in the vagina may also cause infection.