The maximum dose is 320 mg daily. Maximum blood pressure reduction occurs within 4 weeks. For congestive heart failure, the usual dose is 40 mg twice daily. The doses may be increased to 80-160 mg twice daily.
OIG will be responsive to the needs of the TDCJ, the TBCJ, governmental agencies, and the people of Texas, by demonstrating a willingness and ability to impartially investigate administrative and criminal complaints, while protecting the rights of all concerned.
1 The Fc portion of IgG enables it to cross the placenta. (IgG is the only class of antibody that can cross the placenta and enter the fetal circulation.)  Feedback inhibition of B-lymphocyte activation. High levels of IgG feedback to B-lymphocytes to prevent their activation in order to turn off antibody production.