Meaning to close by folding or bringing together is from mid-14c. Sense of to set (someone) free (from) (c.1500) is obsolete except in dialectal phrases such as to get shut of. Colloquial shut-eye for sleep is from 1899. To shut (one's) mouth desist from speaking is recorded from 1340.
Medical Device Regulation Act. Medical Device Amendments of 1976. An Act to amend the Federal Food, Drug, and Cosmetic Act to provide for the safety and effectiveness of medical devices intended for human use, and for other purposes. Enacted by.
medical devices and, at the same time, prevent devices that are not safe and effective from. entering or remaining on the market. Medical device regulation is complex, in part, because of the. wide variety of items that are categorized as medical devices; examples range from a simple. tongue depressor to a life-sustaining heart valve. The regulation of medical devices can affect. their cost, quality, and availability in the health care system.