Cases of severe hepatotoxicity, including hepatic necrosis, life-threatening hepatic failure, and fatal events, have been reported with Cipro XR. Acute liver injury is rapid in onset (range 1â39 days), and is often associated with hypersensitivity. The pattern of injury can be hepatocellular, cholestatic or mixed.
The Dolomites are a part of the mountain range of the Italian Alps. They are mostly spread in the province of Belluno and to a lesser degree in the provinces of Trento and Bolzano-Bozen, all of which are located in north eastern part of Italy.
The northern and southern borders are defined by the Puster Valley and the Sugana Valley (Italian: Valsugana). The Dolomites are nearly equally shared between the provinces of Belluno, South Tyrol and Trentino. number of long distance footpaths run across the Dolomites, which are called alte vie (i.e., high paths). Such long trails, which are numbered from 1 to 8, require at least a week to be walked through and are served by numerous Rifugi (huts).