Sertraline should not be taken with or within two weeks of taking monoamine oxidase inhibitors (MAOIs). These include phenelzine (NardilÂ®), tranylcypromine (ParnateÂ®), isocarboxazid (MarplanÂ®), rasagiline (AzilectÂ®), and selegiline (EmsamÂ®).
Pure caffeine is a white, tasteless substance that makes up as much as 5% of. the weight of tea leaves. By structure, caffeine is closely related to the purine bases, guanine and adenine, found in deoxyribonucleic acids (DNA).
Caffeine can be classified as an alkaloid, a term used for substances produced as end products of nitrogen metabolism in some plants. The chemical formula is C 8 H 10 N 4 O 2. Caffeine has a molar mass of 194.19 grams (6.85 ounces).It is soluble in water and in many organic solvents, and it appears in pure form as white crystals. Caffeine can be prepared by extraction from natural sources or by synthesis from uric acid. therapeutic dose of caffeine is about the same as the amount found in an average cup of coffee, between 100 and 200 milligrams (0.0071 ounces). Decaffeinated coffee can be prepared through extraction with a solvent (such as methylene chloride), water extraction, or steam extraction.