Medical Dictionary. arrhythmia. play. noun arÂ·rhythÂ·mia \Ä-Ërith-mÄ-É\. Medical Definition of arrhythmia. : an alteration in rhythm of the heartbeat either in time or force.
Central metabolism provides mechanisms for the generation of energy from carbon-energy source catabolism and the production of biosynthetic precursors and intermediates for the anabolic pathways essential to maintain cell structure and function.
Mitochondrial dysfunction produces syndromes involving muscle and the central nervous system. Although some energy can be obtained quickly from glucose or glycogen through anaerobic glycolysis, most of the energy derives from oxidation of carbohydrates and fatty acids in the mitochondria. The common metabolic product of sugars and fats is acetyl-CoA, which enters the Krebs cycle.