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1 Squalene is a component of some adjuvants that are added to vaccines to enhance the immune response. 2  MF59, an adjuvant produced by Novartis and added to the FLUAD flu vaccine, is such an example. 3  Squalene by itself is not an adjuvant, but emulsions of squalene with surfactants do enhance the immune response.hat is squalene? 1  Squalene is a naturally occurring substance found in plants, animals, and humans. 2  Squalene is also found in a variety of foods, cosmetics, over-the-counter medications, and health supplements. 3  Squalene is commercially extracted from fish oil, and in particular shark liver oil.
Squalamine is a chemical produced from the stomach and the liver of the spiny dogfish shark. Squalamine can also be made in the laboratory. People take squalamine as an antibiotic to fight bacterial infections. The lab-made version of squalamine is sometimes applied directly to the skin as an antibiotic. Some researchers are studying squalamine to see if it might be effective against solid tumors in children.