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Assessment of Depression in Advanced Illness. What Symptoms to Look for and How to Assess. Somatic symptoms (e.g., changes in appetite, weight, energy level, libido, or sleeping) are almost invariably present in patients with advanced illness.
According to the DSM-5, a manual used to diagnose mental disorders, depression occurs when you have at least five of the following symptoms at the same time: 1  A depressed mood during most of the day, particularly in the morning. 2  Fatigue or loss of energy almost every day. 3  Feelings of worthlessness or guilt almost every day.