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What Does Extended Release Mean in Medications? Over-the-counter pills come in many formulas, such as time release, controlled release, extended release, delayed release or sustained release. How does time release work, and what are the advantages and disadvantages to it? What should you know before choosing a standard or time release formula?
Immediate release formulations should be given two or three times a day to provide symptom coverage throughout the day. Extended release and long-acting medications that last for 8 to 12 hours should be taken once a day in the morning. The capsules with beads may be opened if a person has trouble swallowing, however, the beads should be swallowed whole without chewing.