First are dose-response studies. The dose of trazodone needed to induce and maintain sleep is not well understood. Thus, clinicians use anywhere from 25 mg to 150 mg taken at bedtime as a hypnotic dose. This is a critical question because it is recognized that at high doses these medications carry a high safety risk.
Ceruminous gland tumors arise in the external auditory canal (EAC) from specialized glands that are closely related to apocrine glands,which are found in the axillae, anogenital area, areolae, and eyelids (glands of Moll).
Pineal gland. Pineal gland or epiphysis (in red in back of the brain). The pineal gland, also known as the pineal body, conarium or epiphysis cerebri, is a small endocrine gland in the vertebrate brain. The shape of the gland resembles a pine cone, hence its name. The pineal gland is located in the epithalamus, near the center of the brain, between the two hemispheres, tucked in a groove where the two halves of the thalamus join. The pineal gland produces melatonin, a serotonin derived hormone which modulates sleep patterns in both circadian and seasonal cycles.