Continue cooking about 50-80 minutes or until the meat registers 145 degrees on a meat thermometer. Some roasts are long and thin and others are short and fat, consequently the cooking times will vary depending on the shape of your roast. The meat thermometer is the best way to judge the right amount of cooking time.
Endophthalmitis is an inflammation of the inside of the eye. Inflammation affects the vitreous fluid in center of the eye. Vitreous fluid is a clear, gel-like substance. The inflammation can extend to surrounding tissues responsible for vision. Endophthalmitis is rare. In most cases, an infection triggers this inflammation.
Most cases of endophthalmitis are exogenous, resulting from inoculation of organisms from the outside, via trauma, eye surgery, or as an extension of keratitis (corneal infection). In such cases, the aqueous humor may be seeded first before extension into the vitreous. The remaining cases are endogenous, resulting from bacteremic or fungemic seeding of the eye. In endogenous endophthalmitis, organisms usually seed the highly vascular choroid first then extend anteriorly into the vitreous. Most cases of endophthalmitis are due to bacteria and present acutely.