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Anatomy and Physiology. Internal derangement of the knee is a mechanical disorder of the knee which interferes with normal joint motion and/or mobility. A fragment of soft tissue or bone that suddenly becomes interposed between the articular surfaces is the classic cause of internal derangement.natomy and Physiology. Internal derangement of the knee is a mechanical disorder of the knee which interferes with normal joint motion and/or mobility. A fragment of soft tissue or bone that suddenly becomes interposed between the articular surfaces is the classic cause of internal derangement.
Internal derangement of the knee may involve injury to muscle, ligament, tendon, meniscus, or bone. Rehabilitation will depend on the nature of the underlying pathology, the extent of injury, type of treatment (i.e., surgical, nonsurgical), and the functional goals of the individual.he knee has four major ligaments and each is vulnerable to injury: the anterior cruciate ligament (ACL), the medial collateral ligament (MCL) the posterior cruciate ligament (PCL) and the lateral collateral ligament (LCL). Each ligament restricts certain abnormal movement of the knee.