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Biochemistry of Dog Coat Color. The color of a dogâs coat is determined by relative levels of two pigments: eumelanin, which can be either brown or black, and pheomelanin, which is yellow to orange or red. Both pigments are generated by metabolism of tyrosine. A schematic diagram of the pathway is below. Schematic of the melanin synthesis pathways.
Collie Color: The two base colors in collies are sable and black & tan. Most of us know, that in collies, sable is dominant and tri-color recessive. A puppy inherits one color allele from each parent. An allele is an alternate form of a gene. Therefore, if a collie inherits a dominant sable allele from each parent, he/she is a pure for sable (homozygous for sable). On the other hand, if a recessive black & tan color allele is contributed by each parent, the collie will be a tri-color (homozygous for black & tan).