Bismuth subsalicylate may cause ringing in the ears, but that side effect is rare. Possible side effects from loperamide include skin rash, constipation, drowsiness, dizziness, tiredness, dry mouth, nausea, vomiting, and swelling, pain, and discomfort in the abdomen.
In the United States, the annual cost of soil erosion for both on-site and off-site effects has been estimated at 44 billion dollars a year (Pimentel et al., 1995). In the European Union, the figure is 38 billion Euros a year (Montanarella, 2007).
Research indicates that effects on ecosystem services costs (i.e. those processes that the natural world provides to humanity)has reached over $250 million per year in the U.S. Each well pad (in average 10 wells per pad) needs during preparatory and hydraulic fracturing process about 800 to 2,500 days of noisy activity, which affect both residents and local wildlife.