1 For example, the disorder sickle cell anaemia is caused by a mutation in the gene that instructs the building of a protein called haemoglobin. 2  This causes the red blood cells to become an abnormal, rigid, sickle shape. 3  However, in African populations, having this mutation also protects against malaria.
Optimistic time - generally the shortest time in which the activity can be completed. It is common practice to specify optimistic times to be three standard deviations from the mean so that there is approximately a 1% chance that the activity will be completed within the optimistic time.
How it works. A typical session lasts for around 30 minutes though there are many variations that can extend this to a 1 hour teambuilding session or it can be used as a 5 minute ice breaker. The basic teambuilding activity is simply completing 10 steps in a row without anyone touching the ground.