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Freebase(0.00 / 0 votes)Rate this definition: OSIsoft. OSIsoft, LLC is a worldwide manufacturer of Application software for real-time data infrastructure solutions, called the PI System. Founded in 1980, OSIsoft, LLC is privately held and headquartered in San Leandro, CA, with operations worldwide.
OSI reference model (Open Systems Interconnection) OSI (Open Systems Interconnection) is reference model for how applications can communicate over a network. A reference model is a conceptual framework for understanding relationships. The purpose of the OSI reference model is to guide vendors and developers so the digital communication products and software programs they create will interoperate, and to facilitate clear comparisons among communications tools.