Duloxetine is also sometimes used to treat stress urinary incontinence (leakage of urine during physical activity such as coughing, sneezing, laughing, and exercise) in women. Talk to your doctor about using this medication to treat your condition.
Water's density maximum is a product of the same phenomenon. Close to the freezing point, the water molecules start to arrange locally into ice-like structures. This creates some openness in the liquid water, which tends to decrease its density.
A solution of 76.7% water and 23.3% salt will freeze at -21.1 degrees Celsius, which is why adding salt to ice will melt it when the temperature is below freezing. The boiling point increases by the same principle of disturbing the homogeneous fluid.