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This medication also is frequently used to administer general anesthesia for surgery. Propofol requires different patient monitoring during the procedure and, depending upon circumstances, may require anesthesia personnel, and so involve additional patient cost. Most of the time, the medicine is given through a vein.
Remifentanil is a potent, short-acting synthetic opioid analgesic drug. It is given to patients during surgery to relieve pain and as an adjunct to an anaesthetic. Remifentanil is used for sedation as well as combined with other medications for use in general anesthesia. The use of remifentanil has made possible the use of high-dose opioid and low-dose hypnotic anesthesia, due to synergism between remifentanil and various hypnotic drugs and volatile anesthetics.