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This condition can be caused by certain medications and by infections. In some cases, it is caused by a cancer or precancerous condition. Myelofibrosis, bone marrow scarring that can result from various hematologic cancers, typically leads to low blood counts. Pancytopenia can also be caused by aplastic anemia, a bone marrow failure disorder that affects blood cell production.
Low white blood cell counts (WBC) can be particularly problematic, because your white blood cell count is so closely tied to your immune systemâs ability to protect you from infection. Because a low white blood count can be life threatening, itâs a good idea to familiarize yourself with the symptoms and terminology. When you get your blood work, the lab will be looking for: Leukopenia â A decrease in the total number of white blood cells, which can lead to a lowered white blood cell count. Neutropenia â A decrease in the number of neutrophils, also creating a lower WBC. Granulocytopenia â Another term that may be used for Neutropenia.