Duloxetine is also sometimes used to treat stress urinary incontinence (leakage of urine during physical activity such as coughing, sneezing, laughing, and exercise) in women. Talk to your doctor about using this medication to treat your condition.
Water's density maximum is a product of the same phenomenon. Close to the freezing point, the water molecules start to arrange locally into ice-like structures. This creates some openness in the liquid water, which tends to decrease its density.
Why does sweetness of coke change after freezing completely. Substances in solution have the effect of decreasing the temperature of the freezing point of the liquid they are dissolved in. This is called freezing-point depression. This is one of the reasons why adding salt to ice helps it melt.