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This condition can be caused by certain medications and by infections. In some cases, it is caused by a cancer or precancerous condition. Myelofibrosis, bone marrow scarring that can result from various hematologic cancers, typically leads to low blood counts. Pancytopenia can also be caused by aplastic anemia, a bone marrow failure disorder that affects blood cell production.
The normal range of low to high WBC counts also varies by age and gender. A low WBC count is often linked to problems with the bone marrow and the inability to make enough white blood cells. Autoimmune diseases that attack your white blood cells can also lead to a low WBC count.Several different prescribed drugs, including chemotherapy, are known to decrease WBC production or destroy WBCs.A low WBC count can be serious because it increases your risk of developing a potentially life-threatening infection. normal WBC count is approximately 4,500 to 10,000 WBCs per microliter of blood. A low WBC count is generally below 3,500 WBCs per microliter of blood, but this number varies depending on the medical laboratory, the particular test used, and the individual medical practice.