Rose DeVore with and 4 others at Violet Township, Fairfield County, Ohio. 1  Jimmy Lee Frazier II at Violet Township, Fairfield County, Ohio. 1  Carey Frazier was watching Game of Thrones at  2  Jimmy Lee Frazier II at  3  Bunny Rickenbacker at
1 Understand that hepatitis B vaccination-induced protective antibodies can last for up to 15 years, but appear to fall off over time.2  Patients who were vaccinated 10 to 15 years ago, especially those who were vaccinated as children, may not be adequately protected. Patients who were vaccinated 10 to 15 years ago, especially those who were vaccinated as children, may not be adequately protected. 2  For patients with this history who are at moderate to high risk of hepatitis B infection consider quantitative hepatitis B antibody measurement to determine protective immunity.
The first dose protects your body (for the short-term) in an estimated two to four weeks. Once you receive the second dose (about six to 12 months after the first), the vaccine should work for at least 20 years. Studies estimate, however, that the vaccine may last over the course of your lifetime.