As folate is vital in the first trimester of pregnancy for healthy fetal development, the use of antifolates is strongly contraindicated in pregnancy and carries significant teratogenic risk. Low doses of methotrexate can deplete folate stores and cause side-effects that are similar to folate deficiency.
Cause of Adult Mumps. Adult mumps is caused by an infection with the mumps virus, which is found worldwide. The mumps virus is an RNA (ribonucleic acid) virus from the family Paramyxovirus of the genus Rubulavirus. The mumps virus only infects humans.
Mumps is a contagious viral infection spread by bodily fluids that causes uncomfortable symptoms like swelling of the salivary glands, fever, body aches, and fatigue. In some cases, people who contract mumps have no symptoms. Rarely, people will develop serious complications with mumps, including inflammation of the brain and spinal cord. The Centers for Disease Control and Prevention report less than 1000 cases annually, thanks to widespread vaccination.