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Lack of evidence: There is little evidence to suggest that low dose Seroquel is an effective treatment for insomnia. Despite the drugâs perception of being an effective treatment for insomnia, there is minimal evidence in support of these claims.
The Nonbenzodiazepines: Overview. Nonbenzodiazepines for insomnia include zolpidem (Ambien, Ambien CR, Edluar, Zolpimist, Intermezzo), eszopiclone (Lunesta), and zaleplon (Sonata). These drugs should be taken only if needed for insomnia; they do not need to be taken every night if you can get to sleep without them.