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This medication also is frequently used to administer general anesthesia for surgery. Propofol requires different patient monitoring during the procedure and, depending upon circumstances, may require anesthesia personnel, and so involve additional patient cost. Most of the time, the medicine is given through a vein.
When a sedative is called for, the most commonly used drug is midazolam, which is a short-acting sedative in the same class of drugs as lorazepam, said Abenstein, who is also an associate professor of anesthesiology at the Mayo Clinic in Rochester, Minn. Most patients, however, are not sedated before an operation.