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Antibiotics will stay in your system fro 7 to 10 days.... Antibiotics will stay in your system fro 7 to 10 days. The actual time will depend upon the type of antibiotic taken, the dosage of the antibiotic taken and individual human body as well. Some antibiotics may stay for shorter durations than this also. jack perry.
Best Answer: Depends on the antibiotic, doses, own's metabolism, etc. Most antibiotics are designed to stay in your system at a therapeutic level for 7 to 10 days. That means that they are actually killing bacteria. However, the effects on your body after finishing the full course of the drug, can last up to 6 months. What you need to understand is that you have bacteria in your intestines, called the normal flora, that are necessary to keep you healthy.