Macular thickness, as measured by OCT, is one of the key outcome measures used in most clinical trials, especially those on diabetic macular edema and AMD. Because Stratus TD-OCT was the most common commercially available OCT instrument in the past decade, most trials are designed based on Stratus OCT.
A percentile (or a centile) is a measure used in statistics indicating the value below which a given percentage of observations in a group of observations fall. For example, the 20th percentile is the value (or score) below which 20% of the observations may be found. The term percentile and the related term percentile rank are often used in the reporting of scores from norm-referenced tests.
A percentile is the position of an observation in the data set relative to the other observations in the data set. Specifically the percentile represents the percentage of the sample that falls below this observation. 50th percentile because half of the data or 50% of the observations lie below the median.