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Alanine aminotransferase (ALT): An enzyme that is normally present in liver and heart cells. ALT is released into blood when the liver or heart is damaged.The blood ALT levels are thus elevated with liver damage (for example, from viral hepatitis) or with an insult to the heart (for example, from a heart attack).Some medications can also raise ALT levels.LT is released into blood when the liver or heart is damaged. The blood ALT levels are thus elevated with liver damage (for example, from viral hepatitis) or with an insult to the heart (for example, from a heart attack).
Reference Range. Alanine aminotransferase (ALT) is an enzyme found primarily in the liver and kidney. It was originally referred to as serum glutamic pyruvic transaminase (SGPT). Normally, a low level of ALT exists in the serum. ALT is increased with liver damage and is used to screen for and/or monitor liver disease.