Duloxetine is also sometimes used to treat stress urinary incontinence (leakage of urine during physical activity such as coughing, sneezing, laughing, and exercise) in women. Talk to your doctor about using this medication to treat your condition.
Water's density maximum is a product of the same phenomenon. Close to the freezing point, the water molecules start to arrange locally into ice-like structures. This creates some openness in the liquid water, which tends to decrease its density.
At some point, the amount of heat removed is great enough that the attractive forces between molecules draw the molecules close together, and the liquid freezes to a solid. The temperature of a freezing liquid remains constant, even when more heat is removed.