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Freebase(0.00 / 0 votes)Rate this definition: OSIsoft. OSIsoft, LLC is a worldwide manufacturer of Application software for real-time data infrastructure solutions, called the PI System. Founded in 1980, OSIsoft, LLC is privately held and headquartered in San Leandro, CA, with operations worldwide.
The Open System Interconnection (OSI) protocol suite is comprised of numerous standard protocols that are based on the OSI reference model. These protocols are part of an international program to develop data-networking protocols and other standards that facilitate multivendor equipment interoperability. The OSI program grew out of a need for international networking standards and is designed to facilitate communication between hardware and software systems despite differences in underlying architectures.