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High BUN indicates increased protein breakdown, which is associated with decreased immune function. A study shows that patients with elevated BUN (> 20 mg/dl) have an increased risk of infection (R). High BUN is associated with increased mortality in critically ill patients (R, R, R, R).
Quick Answer. A high BUN count usually indicates that the kidneys are not working properly, but there are other issues that can cause high results, as stated by Mayo Clinic. Some other causes for a high BUN count are a high protein diet, dehydration and congestive heart failure. BUN is an acronym for blood urea nitrogen, and results can vary depending on an individual's age as well as the lab that processes the test, as explained by Mayo Clinic. Shock, severe burns and some medications, such as certain antibiotics, can also cause higher-than-normal BUN results. Doctors consider a BUN test a standard type of blood test and use it to measure the amount of urea nitrogen in the blood. The liver breaks down proteins in the body, which causes ammonia production, according to Mayo Clinic.