About H2 blockers. H2 blockers â also known as histamine 2 receptor antagonists â are medications that decrease the amount of acid the stomach produces. These drugs are used to treat various gastrointestinal disorders.2 blockers work by preventing the action of histamine, a substance released by the human immune system during allergic reactions. Histamine normally interacts with gastric H2 receptors to produce stomach acid. The H2 blockers inhibit this response and help reduce gastric acid output.
How long does it take to cook a 2.5-pound meatloaf? Recipes vary, but a meatloaf is generally baked for between 1 to 1 1/2 hours in a 350 to 400 degree oven. The type of meat and fillers used affect the cooking time.
1 Increase oven temperature to 400 degrees F (200 degrees C), and continue baking 15 minutes, to an internal temperature of 160 degrees F (70 degrees C). 2  In a small bowl, mix the remaining tomato sauce and ketchup. 3  Pour over the top of the meatloaf, and continue baking 10 minutes. Increase oven temperature to 400 degrees F (200 degrees C), and continue baking 15 minutes, to an internal temperature of 160 degrees F (70 degrees C). 2  In a small bowl, mix the remaining tomato sauce and ketchup. 3  Pour over the top of the meatloaf, and continue baking 10 minutes.