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In most cases, people with vastly elevated liver enzymes should stop taking Crestor or other statin drugs.The normal starting dose of Crestor is 10mg per day. The maximum dose of Crestor is 40 mg per day. Crestor therapy usually starts with a 10mg dose.Sometimes the doctor willstart with a 20mg dose. The 40mg dose is reserved for people who are on 20mg but still are not meeting their cholesterol goals.Crestor's labeling contains comparisons to Lipitor.he maximum dose of Crestor is 40 mg per day. Crestor therapy usually starts with a 10mg dose. Sometimes the doctor willstart with a 20mg dose. The 40mg dose is reserved for people who are on 20mg but still are not meeting their cholesterol goals.Crestor's labeling contains comparisons to Lipitor.
Crestor Dosage for High Cholesterol. The recommended starting dose for most people with high cholesterol is Crestor 10 mg once a day (although a starting dose of 20 mg daily can be used if you have very high cholesterol).After several weeks, your healthcare provider will recommend that you return to recheck your cholesterol levels.he dose can also be decreased if side effects occur. The average daily dose is Crestor 20 mg to Crestor 40 mg once a day. Your healthcare provider may recommend a lower Crestor dose (5 or 10 mg per day, depending on the particular circumstances) if you: 1  Are 65 years of age or older.