About H2 blockers. H2 blockers â also known as histamine 2 receptor antagonists â are medications that decrease the amount of acid the stomach produces. These drugs are used to treat various gastrointestinal disorders.2 blockers work by preventing the action of histamine, a substance released by the human immune system during allergic reactions. Histamine normally interacts with gastric H2 receptors to produce stomach acid. The H2 blockers inhibit this response and help reduce gastric acid output.
How long does it take to cook a 2.5-pound meatloaf? Recipes vary, but a meatloaf is generally baked for between 1 to 1 1/2 hours in a 350 to 400 degree oven. The type of meat and fillers used affect the cooking time.
If for any reason, you still insist at baking your meatloaf at 400 degrees, then you should probably make it rather thin, to avoid the above-mentioned issues. If you make it about 1 â 1 and 1/2 inches thick, it should bake fairly even on the outside and the inside. Suggested time ranges from 30 to 45 minutes.