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Orchitis (or-KIE-tis) is an inflammation of one or both testicles. It is usually caused by a bacterial infection or by the mumps virus. Bacterial orchitis can be caused by sexually transmitted infections (STIs), particularly gonorrhea or chlamydia. Bacterial orchitis often results from epididymitis, an inflammation of the coiled tube (epididymis) at the back of the testicle that stores and carries sperm. In that case, it's called epididymo-orchitis.
Inflammation of the Testicle (Orchitis) Orchitis Facts. Orchitis is an inflammatory condition of one or both testicles in males, generally caused by a viral or bacterial infection. Most cases of orchitis in children are caused by infection with the mumps virus. Orchitis caused by a bacterial infection most commonly develops from the progression of epididymitis, an infection of the tube that carries semen out of the testicles. This is called epididymo-orchitis.