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Making the world better, one answer at a time. Thin air is caused by low oxygen pressure at high altitudes. The lack of oxygen makes the air less dense. Thin air is caused by low oxygen pressure at high altitudes. The lack of oxygen makes the air less dense.
The physical changes or causes are airway obstruction by thick mucus or by poor lung tissue compliance (the elasticity, or ability of the lung tissue to expand) that can either block air from entering the alveoli or by not permitting the alveoli to expel CO2 because the elastic tissue becomes nonfunctional.