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Thick blood is caused by a variety of conditions, such as heavy proteins in the blood, too much blood in circulation or a blood clot system imbalance, according to Southeastern Medical Oncology Center. Diseases such as cancer and lupus can also lead to thick blood. Continue Reading.
High blood pressure causes thickening of the walls of blood vessels and also makes them more likely to develop hardening of the arteries (atherosclerosis). People with thickened blood vessel walls and atherosclerosis are at higher risk of stroke, heart attack, and kidney failure.