In enzymes, some of these amino acids form a site in the structure that catalyzes the enzymatic reaction. This site, called the active site of the enzyme, has amino acids that bind specifically to the substrate molecule, also called a ligand (Fig. 2). In a similar manner, certain sites in cell receptor proteins bind to specific ligand molecules that the receptor recognizes.
When did France's second empire end? The Second Empire ended with the swift and catastrophic defeat of  France in the Franco-Prussian war of 1870. The war was engineered  by Bismarck with the idea that Germany â¦would be united.This  included the capture by the Prussians of the Napoleon III. Then the  proclamation at Versailles of the German Empire, the loss to France  of Alsace and Lorraine, and the proclamation of the Third Republic.
First Reich was the Holy Roman Empire from 800 to 1648 (formally ended in 1806). Second Reich was Hohenzollern Germany under Bismarck, from 1870 to the fall of Wilhelm II in 1919. So Nazi Germany was the third reich (regime) in Germany.eich can be translated as nation, realm or empire. For example, France is Frankreich or Realm of the Franks in German. In this usage, the first reich was the Holy Roman Empire, destroyed by Napoleon, and the second reich was Imperial Germany unitl the end of World War I.