Serous Membrane Serous Membrane is composed of a layer simple squamous epithelium resting on a thin layer of areolar connective tissue. The Serous membranes line body cavities that are closed to the exterior. Serous membrane occurs in pairs. The parietal layer lines a specific portion of the wall of the ventral body cavity. It folds in on itself to form the visceral layer, which then converts the outside of the organs in that cavity. These layers are separated by a scanty amount of thin, clear fluid, called serous fluid, which is secreted by both membranes.
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Lipophilic efficiency (LiPE), sometimes referred to as ligand-lipophilicity efficiency (LLE) is a parameter used in drug design and drug discovery to evaluate the quality of research compounds, linking potency and lipophilicity in an attempt to estimate druglikeness.igh potency (high value of pIC 50) is a desirable attribute in drug candidates, as it reduces the risk of non-specific, off-target pharmacology at a given concentration. When associated with low clearance, high potency also allows for low total dose, which lowers the risk of idiosyncratic drug reaction.