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Lack of evidence: There is little evidence to suggest that low dose Seroquel is an effective treatment for insomnia. Despite the drugâs perception of being an effective treatment for insomnia, there is minimal evidence in support of these claims.
Seroquel for Anxiety. Seroquel is an atypical antipsychotic drug approved to treat schizophrenia and bipolar disorder, but it is increasingly being prescribed off-label to treat anxiety disorders. Seroquel XR (extended release tablets) is also FDA approved to treat major depressive disorder as add-on therapy in people taking an antidepressant medication.