Duloxetine is also sometimes used to treat stress urinary incontinence (leakage of urine during physical activity such as coughing, sneezing, laughing, and exercise) in women. Talk to your doctor about using this medication to treat your condition.
Water's density maximum is a product of the same phenomenon. Close to the freezing point, the water molecules start to arrange locally into ice-like structures. This creates some openness in the liquid water, which tends to decrease its density.
1 For other liquids, solidification when the temperature drops includes the lowering of kinetic energy, which allows molecules to pack more tightly and makes the solid denser than its liquid form.  Because ice is less dense than water, it is able to float at the surface of water.