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endothelial cell. (histology). A type of squamous epithelial cell composing the endothelium. 1  Facebook. 2  Twitter.
Endothelial cells are epithelial cells that form a thin layer of simple squamous epithelium known as endothelium. Endothelium makes up the inner layer of vessels such as arteries, veins, and lymphatic vessels. In the smallest blood vessels, capillaries and sinusoids, endothelium comprises the majority of the vessel.