Once released, BNP binds to and activates the atrial natriuretic factor receptor NPRA, and to a lesser extent NPRB, in a fashion similar to atrial natriuretic peptide (ANP) but with 10-fold lower affinity.
The GTP layer for the control plane (GTP-C) tunnels signaling messages between GSNs in the GPRS backbone network.The GTP-C enables several procedures to be performed through the GPRS backbone network, including path management, tunnel management, location management, and mobility management.he GTP layer for the control plane (GTP-C) tunnels signaling messages between GSNs in the GPRS backbone network.
Modulators of the Notch signal, e.g., the Numb protein are able to antagonize Notch effects, resulting in the halting of cell cycle and differentiation of NPCs. In this way, Notch signaling controls NPC self-renewal as well as cell fate specification.odulators of the Notch signal, e.g., the Numb protein are able to antagonize Notch effects, resulting in the halting of cell cycle and differentiation of NPCs. In this way, Notch signaling controls NPC self-renewal as well as cell fate specification.