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Freebase(0.00 / 0 votes)Rate this definition: OSIsoft. OSIsoft, LLC is a worldwide manufacturer of Application software for real-time data infrastructure solutions, called the PI System. Founded in 1980, OSIsoft, LLC is privately held and headquartered in San Leandro, CA, with operations worldwide.
OSI model. The Open Systems Interconnection model (OSI model) is a conceptual model that characterizes and standardizes the communication functions of a telecommunication or computing system without regard to their underlying internal structure and technology. Its goal is the interoperability of diverse communication systems with standard protocols.