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Alanine aminotransferase (ALT): An enzyme that is normally present in liver and heart cells. ALT is released into blood when the liver or heart is damaged.The blood ALT levels are thus elevated with liver damage (for example, from viral hepatitis) or with an insult to the heart (for example, from a heart attack).Some medications can also raise ALT levels.LT is released into blood when the liver or heart is damaged. The blood ALT levels are thus elevated with liver damage (for example, from viral hepatitis) or with an insult to the heart (for example, from a heart attack).
Test Overview. An alanine aminotransferase (ALT) test measures the amount of this enzyme in the blood. ALT is found mainly in the liver, but also in smaller amounts in the kidneys , heart, muscles, and pancreas . ALT was formerly called serum glutamic pyruvic transaminase (SGPT). ALT is measured to see if the liver is damaged or diseased.