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Lack of evidence: There is little evidence to suggest that low dose Seroquel is an effective treatment for insomnia. Despite the drugâs perception of being an effective treatment for insomnia, there is minimal evidence in support of these claims.
Supplements that contain melatonin precursors, such as L-tryptophan and 5-HTP, have not been proven effective in treating insomnia, and there are safety concerns that they may be linked to debilitating condition called eosinophilia-myalgia syndrome (EMS).