In enzymes, some of these amino acids form a site in the structure that catalyzes the enzymatic reaction. This site, called the active site of the enzyme, has amino acids that bind specifically to the substrate molecule, also called a ligand (Fig. 2). In a similar manner, certain sites in cell receptor proteins bind to specific ligand molecules that the receptor recognizes.
When did France's second empire end? The Second Empire ended with the swift and catastrophic defeat of  France in the Franco-Prussian war of 1870. The war was engineered  by Bismarck with the idea that Germany â¦would be united.This  included the capture by the Prussians of the Napoleon III. Then the  proclamation at Versailles of the German Empire, the loss to France  of Alsace and Lorraine, and the proclamation of the Third Republic.
Best Answer: Hitler was referring to the Autocratic German empire ruled by Otto Von Bismark during the first world war, which was commonly known as the Second Reich. The Holy Roman Empire was considered the First Reich. Well, it was a reference to Germans trying to get back their Glory Days when Germany was a strong country (the Weimar Republic really hurt for a lot of Germans). The first reich was the Holy Roman Empire (I know, but I didn't make the reichs). The second was the German Empire of 1871â1918. Presumably the Third Reich was going to follow in these two Empires. The history of modern German is often summarised as being 'three reichs and three democracies'.