Once released, BNP binds to and activates the atrial natriuretic factor receptor NPRA, and to a lesser extent NPRB, in a fashion similar to atrial natriuretic peptide (ANP) but with 10-fold lower affinity.
The GTP layer for the control plane (GTP-C) tunnels signaling messages between GSNs in the GPRS backbone network.The GTP-C enables several procedures to be performed through the GPRS backbone network, including path management, tunnel management, location management, and mobility management.he GTP layer for the control plane (GTP-C) tunnels signaling messages between GSNs in the GPRS backbone network.
The notch signaling mechanism is an example of juxtacrine signaling (also known as contact-dependent signaling) in which two adjacent cells must make physical contact in order to communicate. This requirement for direct contact allows for very precise control of cell differentiation during embryonic development.uch networks are complex systems in their organization and may exhibit a number of emergent properties including bistability and ultrasensitivity. Analysis of cell signaling networks requires a combination of experimental and theoretical approaches including the development and analysis of simulations and modeling.