In enzymes, some of these amino acids form a site in the structure that catalyzes the enzymatic reaction. This site, called the active site of the enzyme, has amino acids that bind specifically to the substrate molecule, also called a ligand (Fig. 2). In a similar manner, certain sites in cell receptor proteins bind to specific ligand molecules that the receptor recognizes.
When did France's second empire end? The Second Empire ended with the swift and catastrophic defeat of  France in the Franco-Prussian war of 1870. The war was engineered  by Bismarck with the idea that Germany â¦would be united.This  included the capture by the Prussians of the Napoleon III. Then the  proclamation at Versailles of the German Empire, the loss to France  of Alsace and Lorraine, and the proclamation of the Third Republic.
The Third Reich would be the third german empire in history. The first was the Holy Roman Empire. The second was the Second Empire of 1871-1918. However, the term Third Reich was more popular in other countries. In Germany, it was merely called The Reich. The Nazis called their empire the Greater German Reich. Hitler led Nazi Germany until it was defeated in World War Two in 1945 and Battle of Berlin#Berlin fell, when he killed himself. The Nazi Party was destroyed in the same year as its lead