Macular thickness, as measured by OCT, is one of the key outcome measures used in most clinical trials, especially those on diabetic macular edema and AMD. Because Stratus TD-OCT was the most common commercially available OCT instrument in the past decade, most trials are designed based on Stratus OCT.
A percentile (or a centile) is a measure used in statistics indicating the value below which a given percentage of observations in a group of observations fall. For example, the 20th percentile is the value (or score) below which 20% of the observations may be found. The term percentile and the related term percentile rank are often used in the reporting of scores from norm-referenced tests.
One definition of percentile, often given in texts, is that the P-th percentile (< â¤) of a list of N ordered values (sorted from least to greatest) is the smallest value in the list such that no more than P percent of the data is strictly less than the value and at least P percent of the data is less than or equal to that value.