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Lack of evidence: There is little evidence to suggest that low dose Seroquel is an effective treatment for insomnia. Despite the drugâs perception of being an effective treatment for insomnia, there is minimal evidence in support of these claims.
Skip page links. How long does it take seroquel xr to make you drowsy? I've been on regular seroquel 100 mg every night for bipolar and to help me with my insomnia, now my doctor switched me to seroquel xr 300 mg to be taken at night...and I took it for the first time tonight at 11:30pm and it's now 1:16am and I'm still not sleepy at all.