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Freebase(0.00 / 0 votes)Rate this definition: OSIsoft. OSIsoft, LLC is a worldwide manufacturer of Application software for real-time data infrastructure solutions, called the PI System. Founded in 1980, OSIsoft, LLC is privately held and headquartered in San Leandro, CA, with operations worldwide.
OSI (Open Systems Interconnection) is a standard description or reference model for how messages should be transmitted between any two points in a telecommunicationnetwork. â¦Its purpose is to guide product implementers so that their products will consistently work with other products.