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Eczema is a disease in a form of dermatitis,or inflammation of the epidermis. In rare cases someone vaccinated against smallpox can develop eczema vaccinatum, which can cause organ failure. Ordinary eczema is not deadly.
If you have eczema and get the HSV-1 infection on an eczematous area of your skin, you may experience a blistery rash that can spread quickly. If left untreated, the infection can affect vital organs and, though rare, can be deadly. Because of these consequences, eczema herpeticum is considered a dermatologic emergency.