Additives used in the production of vaccines may include. 1  suspending fluid (e.g. sterile water, saline, or fluids containing protein); 2  preservatives and stabilizers to help the vaccine remain unchanged (e.g. albumin, phenols, and glycine); and. 3  adjuvants or enhancers to help the vaccine to be more effective.
The other element is a standard Yorkie that falls under or over the expected weight and/or size range. Breed standards have changed. The AKC used to list a minimum weight of 4 pounds (1.81 kg). Now, there is only a maximum weight of 7 pounds (3.17 kg) for a full grown, adult Yorkie. Even with this change on paper, most Yorkshire Terriers fit into the 3 to 7 lb. (1.36 kg to 3.17 kg) range. A dog smaller than this, fully grown, would be considered too small and may have size related health issues.
Bigger Than Normal Yorkies. On the other end of the spectrum are owners who are concerned that their dog may be too large. There are a couple of different elements to this as well. First, one may have assumed that their dog was going to fall on the lighter end of the scale and be closer to 4 pounds.