Long known as the âsunshine vitaminâ because the body makes it when skin is exposed to sunlight, vitamin D might now be dubbed the âsuperstar vitamin,â judging by the amount of attention it has garnered of late from researchers and the general public.
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test. Vitamin B12 deficiency can be caused by many factors, one of which is pernicious anemia, a condition resulting in deficient production of intrinsic factor in the parietal cells of the stomach. Intrinsic factor is a protein that is needed to assist in the absorption of vitamin B12 into the small intestine.
Definition. Pernicious anemia is a disease in which the red blood cells are abnormally formed, due to an inability to absorb vitamin B 12. True pernicious anemia refers specifically to a disorder of atrophied parietal cells leading to absent intrinsic factor, resulting in an inability to absorb B 12.s noted, true pernicious anemia refers specifically to a disorder of atrophied parietal cells leading to absent intrinsic factor, resulting in an inability to absorb B 12. However, there are other related conditions that result in decreased absorption of B 12.