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1 Insulin sensitivity is increased, so your cells are better able to use any available insulin to take up glucose during and after activity. 2  When your muscles contract during activity, it stimulates another mechanism that is completely separate of insulin.
When to take insulin or another medication and how much to use depends on when, what, and how much food you eat. It also depends on your level of physical activity since the cells in your body use more sugar when you are active. Hypoglycemia is basically a reaction to too much insulin in your system. The insulin speeds up the lowering of the blood glucose level. Then without eating or with your body burning sugar faster because of physical activity, the level of sugar becomes dangerously low.