Angel (season 1)
At the end of the third season of "Buffy", the 242-year-old, re-ensouled vampire Angel left Sunnydale to give teenage Slayer Buffy Summers the chance to live a normal life. Angel is now living in the big city of Los Angeles. With Buffy gone Angel is now completely cut off from society, every day getting closer and closer to giving in to his vampiric hunger. It's not until he befriends the half demon and fellow Irishman Doyle, who is sent visions of people in trouble by The Powers That Be, and fellow Sunnydale resident Cordelia Chase, who grounds Angel's life in the humanity around him, that he truly begins to take charge of his life and seek atonement for his past sins. He sets up his own detective agency, Angel Investigations and begins to "help the helpless".
Spike (Buffy the Vampire Slayer)
When Fred is killed by Illyria, Spike mourns her death and decides to join Team Angel in her honor. Upon learning that Buffy is now dating The Immortal, Spike and Angel travel to Rome on the pretext of business but spend most of the time there trying to find Buffy. In the end, they fail to catch up with her. (The blonde glimpsed in Rome is later revealed to be a decoy Buffy, set up by Andrew Wells, who had researched the history between Angel, Spike and The Immortal, and thought the idea would be "hilarious".) During the final episodes of "Angel", Spike is the first to vote for Angel's plan to wound the Senior Partners by massacring the Circle of the Black Thorn. He then spends what might be his last hours on Earth returning to his mortal roots as a frustrated poet, triumphantly knocking them dead (figuratively) in an open mic poetry slam at a bar. After single-handedly (literally, he held the baby in one hand and a sword in the other) rescuing an infant and destroying the Fell Brethren, Spike joins Angel, Illyria, and a badly wounded Charles Gunn in the alley behind the Hyperion as the series draws to an end, preparing to incur the apocalyptic wrath of the Senior Partners, as a way of going out in a blaze of glory that will probably cost their lives.