Scrapie
The name scrapie is derived from one of the clinical signs of the condition, wherein affected animals will compulsively scrape off their fleeces against rocks, trees, or fences. The disease apparently causes an itching sensation in the animals. Other clinical signs include excessive lip smacking, altered gaits, and convulsive collapse.
Scrappy Carroll
John E. Carroll was born in Buffalo, New York, in 1860. He was nicknamed "Scrappy", likely due to him having a "pugnacious disposition", and he may have been the first player to have had that nickname.