Early modern period
In the early modern period, the Holy Roman Empire was a union of territories in Central Europe under a Holy Roman Emperor the first of which was Otto I. The last was Francis II, who abdicated and dissolved the Empire in 1806 during the Napoleonic Wars. Despite its name, for much of its history the Empire did not include Rome within its borders.
Antoninus Pius
Antoninus was the last Roman Emperor recognised by the Indian Kingdoms. Raoul McLaughlin quotes Aurelius Victor as saying "The Indians, the Bactrians and the Hyrcanians all sent ambassadors to Antoninus. They had all heard about the spirit of justice held by this great emperor, justice that was heightened by his handsome and grave countenance, and his slim and vigorous figure." Due to the outbreak of the Antonine epidemic and wars against northern Germanic tribes, the reign of Marcus Aurelius was forced to alter the focus of foreign policies, and matters relating to the Far East were increasingly abandoned in favour of those directly concerning the Empire's survival.