Testicular immunology
Mumps is a viral disease which causes swelling of the salivary glands and testes. The mumps virus lives in the upper respiratory tract and spreads through direct contact with saliva. Prior to widespread vaccination programs, it was a common childhood disease. Mumps is generally not serious in children, but in adults, where sperm have matured in the testis, it can cause more severe complications, such as infertility.
Mumps
A physical examination confirms the presence of the swollen glands. Usually, the disease is diagnosed on clinical grounds, and no confirmatory laboratory testing is needed. If there is uncertainty about the diagnosis, a test of saliva or blood may be carried out; a newer diagnostic confirmation, using real-time nested polymerase chain reaction (PCR) technology, has also been developed. As with any inflammation of the salivary glands, the serum level of the enzyme amylase is often elevated.