Muhammad
Muhammad's life is traditionally defined into two periods: pre-hijra (emigration) in Mecca (from 570 to 622), and post-hijra in Medina (from 622 until 632). Muhammad is said to have had thirteen wives in total (although two have ambiguous accounts, Rayhana bint Zayd and Maria al-Qibtiyya, as wife or concubine.) Eleven of the thirteen marriages occurred after the migration to Medina.
Khadija bint Khuwaylid
Khadijah was the closest to Muhammad and he confided in her the most out of all his following wives. It is narrated in many hadiths that Khadijah was Muhammad's most trusted and favorite among all his marriages. It is narrated in Sahih Muslim: The messenger of Allah said: "God Almighty never granted me anyone better in this life than her. She accepted me when people rejected me; she believed in me when people doubted me; she shared her wealth with me when people deprived me; and Allah granted me children only through her." ‘A’ishah narrated of Muhammed and Khadijah in Sahih Bukhari: "I did not feel jealous of any of the wives of the Prophet as much as I did of Khadijah though I did not see her, but the Prophet used to mention her very often, and when ever he slaughtered a sheep, he would cut its parts and send them to the women friends of Khadijah. When I sometimes said to him, "(You treat Khadijah in such a way) as if there is no woman on Earth except Khadijah," he would say, "Khadijah was such-and-such, and from her I had children." It is also narrated: The Messenger of Allah said: "The best of its women is Khadijah bint Khuwailid, and the best of its women is Maryam bint ‘Imran." Muhammad said about her "She believed in me when the whole world refuted me and she attested to my veracity when the whole world accused me of falsehood. She offered me compassion and loyalty with her wealth when everyone else had forsaken me." Khadeeja was the daughter of Khuwaylid ibn Asad, who was the great grandson of Qusai ibn Kilab.