Chalcedon
The site of Chalcedon is located on a small peninsula on the north coast of the Sea of Marmara, near the mouth of the Bosphorus. A stream, called the Chalcis or Chalcedon in antiquity and now known as the Kurbağalıdere (Turkish: "stream with frogs"), flows into Fenerbahçe bay. There Greek colonists from Megara in Attica founded the settlement of Chalcedon in 685 BC, some seventeen years before Byzantium.
Non-Chalcedonianism
Within the Patriarchates of Alexandria and Antioch, the rejection of the Chalcedonian definition became a cause of schism. While the common people of Egypt and Syria mostly objected to the Council, the Byzantine-Greek minority that formed the ruling class mostly accepted the Council. These two parties vied for possession of the ancient sees of Alexandria and Antioch that formed, at the time, the third and fourth most prestigious sees in Christendom, respectively. Ultimately, neither group absolutely dominated either church. The end result was the existence of two distinct patriarchates of Alexandria and Antioch for almost 1500 years, continuing in the present time. What is now known as the Coptic Orthodox Church of Alexandria is the native Egyptian patriarchal faction of Alexandria that rejected Chalcedon, whereas the Greek Orthodox Church of Alexandria is composed of those who accepted Chalcedon. For Syrians, the Syriac Orthodox Church forms the patriarchal faction of the native Syrian-Semitic population whereas the Greek Orthodox Church of Antioch is composed of those who accepted Chalcedon.