Florida Territory
Beginning in late 1835, Osceola and the Seminole allies began a guerrilla war against the U.S. forces. Numerous generals fought and failed, succumbing to the heat and disease as well as lack of knowledge of the land. It was not until General Thomas Jesup captured many of the key Seminole chiefs, including Osceola who died in captivity of illness, that the battles began to die down. The Seminoles were eventually forced to migrate. Florida joined the Union as the 27th state on March 3, 1845. By this time, almost all of the Seminoles were gone, except for a small group living in the Everglades.
Micanopy
Following the American purchase of Florida from Spain in 1819 through the Adams–Onís Treaty, and the subsequent appointment of Andrew Jackson as territorial governor in 1821, large numbers of American settlers began colonizing northern Florida during the next decade. Micanopy opposed further American settlement of the region. As conflicts arose more frequently between the Seminole and settlers, the Seminole were driven away from the Florida coast and into the extensive wetlands of the interior. By the Treaty of Moultrie Creek in 1823, the Americans seized 24 million acres of Seminole land in northern Florida. The Seminole moved to central and southern territory.