Twenty-second Amendment to the United States Constitution
Some argue that the 22nd Amendment and 12th Amendment bar any two-term president from later serving as vice president as well as from succeeding to the presidency from any point in the presidential line of succession. Others contend that the original intent of the 12th Amendment concerns qualification for "service" (age, residence, and citizenship), while the 22nd Amendment, concerns qualifications for "election", and thus (strictly applying the text) a former two-term president is still eligible to "serve" as vice president (neither amendment restricts the number of times an individual can be elected to the vice presidency), and then succeed to the presidency to serve out the balance of the term (though prohibited from running for election to an additional term).
Michelle Obama
Over the course of the Obama presidency, particularly during the second term, Michelle Obama was subject to speculation over whether she would run for the presidency herself, similarly to predecessor Hillary Clinton. A potential Michelle Obama candidacy was supported by both Samuel L. Jackson and James Clyburn. On April 6, 2009, CNN did a poll on whether she should run for the presidency in 2020, 83% of responders being opposed to the idea. A May 2015 Rasmussen poll found Obama had 22% of support to Clinton's 56% of winning the Democratic nomination, higher than that of potential candidates Elizabeth Warren, Martin O'Malley and Bernie Sanders. Another poll from that month found 71% of Americans believed that Obama should not run for the presidency, only 14% approving. On January 14, 2016, during a town-hall meeting, President Obama was asked if the First Lady could be talked into running. He responded, "There are three things that are certain in life: death, taxes, and Michelle is not running for president. That I can tell you." On March 16, 2016, while speaking in Austin, Texas, Obama denied that she would ever run for the office, citing a desire to "impact as many people as possible in an unbiased way". In the Epilogue to her November 13, 2018 Becoming (book) Obama writes "I have no intention of running for office, ever" recognizing that "politics can be a means for positive change, but this arena is just not for me."