Ridley (Metroid)
Often considered one of the most memorable Nintendo villains, Ridley has been a mainstay of the series, having appeared (through various incarnations) in almost every "Metroid" game to date (all but "", "Metroid Prime Hunters" and ""). He has also appeared in the "Super Smash Bros." series, however, he had not been made a playable character until "Super Smash Bros. Ultimate" in 2018, making it also the first game overall to have Ridley as a playable character.
Copperhead (DC Comics)
Real name unknown, Copperhead is a crime boss in Central City, as well as a former mercenary. She is an antagonist of both Batman and the Flash.
Two-Face placed a large bounty on Batman's head that many super-villains and mercenaries intended to collect, including Copperhead. Alongside several other villains Copperhead tracked down the Bat to a active train. Climbing on board the train Copperhead attempted to kill Batman but he was able to escape by jumping into a flowing stream.
After a brief stint of assassinations and other mercenary jobs, Copperhead was called up to lead her families' crime business in Central City. After a mysterious rival boss started muscling in on her territory she decided to hire several mercenaries to enforce her rule, two of these mercenaries were Shrapnel and Black Spider. However Black Spider was arrested by the Flash for robbing a diamond exchange, and Shrapnel was arrested after murdering the Road Reapers. Soon after this another pair of mercenaries were apprehended by the Flash- Trigger Twins, this prompted Copperhead to open negotiations with the mysterious crimelord whom she discovered was Captain Cold of the Rogues, in order to find away to defeat the Flash. Copperhead followed Cold's plan to eliminate the Flash, but Cold turned on her when he planted a cold bomb in a weapons delivery. The Flash was able to save her after he apprehended Cold, but without any evidence of her involvement she was allowed to walk free.