Astronaut
The first civilian in space was Valentina Tereshkova aboard Vostok 6 (she also became the first woman in space on that mission).
Tereshkova was only honorarily inducted into the USSR's Air Force, which did not accept female pilots at that time. A month later, Joseph Albert Walker became the first American civilian in space when his X-15 Flight 90 crossed the line, qualifying him by the international definition of spaceflight. Walker had joined the US Army Air Force but was not a member during his flight. 
The first people in space who had never been a member of any country's armed forces were both Konstantin Feoktistov and Boris Yegorov aboard Voskhod 1.
Ellen Ochoa
Ellen Ochoa (born May 10, 1958) is an American engineer, former astronaut and former Director of the Johnson Space Center. Ochoa became director of the center upon the retirement of the previous director, Michael Coats, on December 31, 2012. In 1993 Ochoa became the first Hispanic woman in the world to go to space when she served on a nine-day mission aboard the shuttle Discovery.