Kansas City, Missouri
Kansas City is the largest city in the U.S. state of Missouri. According to the U.S. Census Bureau, the city had an estimated population of 488,943 in 2017, making it the 37th most-populous city in the United States. It is the central city of the Kansas City metropolitan area, which straddles the Kansas–Missouri state line. Kansas City was founded in the 1830s as a Missouri River port at its confluence with the Kansas River coming in from the west. On June 1, 1850 the town of Kansas was incorporated; shortly after came the establishment of the Kansas Territory. Confusion between the two ensued and the name Kansas City was assigned to distinguish them soon after.
Isaac McCoy
McCoy, his son John, his daughter Delilah and her missionary husband Johnston Lykins, worked together as missionaries to the Shawnee and Lenape (Delaware), following them to what is now Kansas City, Missouri, on the border of Indian Territory and near their reservations. The younger McCoy established a trading post at Westport, Missouri. He was among the first organizers of Kansas City. His brother-in-law Lykins was elected as one of the city's first mayors.