Manuel I of Portugal
Manuel's mother was the granddaughter of King John I of Portugal, whereas his father was the second surviving son of King Edward of Portugal and the younger brother of King Afonso V of Portugal. In 1495, Manuel succeeded his first cousin, King John II of Portugal, who was also his brother-in-law, as husband to Manuel's sister, Eleanor of Viseu.
António, Prior of Crato
António, Prior of Crato (; 153126 August 1595; sometimes called "The Determined", "The Fighter" or "The Independentist"), was a grandson of King Manuel I of Portugal and claimant of the Portuguese throne during the 1580 dynastic crisis. According to some historians, he was King of Portugal as António I of Portugal for 33 days in 1580. After the crowning of Philip II of Spain as King of Portugal, António claimed the throne until 1583. He was a disciple of Bartholomew of Braga.