Bilateral cingulotomy
Studies in patients that were a subject to bilateral cingulotomy, that involved fMRI analyses, showed that the anterior cingulate cortex has a key role in cognitive control and is highly likely to be involved in the control of attentional response, whereas the dorsal part of that region of the brain was not identified to be involved in such a process, although this is still under dispute. The function of the dorsal part of the cingulate cortex was connected to the sorting out and processing of conflicting information signals. In addition, neuroimaging studies also indicated that the anterior cingulate cortex participates in the modulation of cortical regions that are of higher order as well as sensory processing areas.
Hemoencephalography
Most research in HEG has focused on disorders of the prefrontal cortex (PFC), the cortical region directly behind the forehead that controls high level executive functions such as planning, judgment, emotional regulation, inhibition, organization, and cause and effect determination. The prefrontal cortex is thought essential for all goal-directed and socially-mediated behavior. The PFC is an ideal target for HEG due to both its location on the scalp (behind the forehead, where there is no hair to disrupt the scattering of the red and infrared light) and the susceptibility of its primary functions to learning.