Ridley (Metroid)
Ridley returns in his Meta form once again in "", where he, along with the Space Pirate legion under his command, are corrupted by Dark Samus. He encounters and battles Samus on Norion, a Galactic Federation-occupied world, and the two fight while free-falling down an air shaft. Ridley is later supercharged with Phazon, becoming "Omega Ridley", and is charged with guarding the Leviathan Seed on the Space Pirate homeworld. He is confronted once again by Samus, and despite being defeated, he survives the fight and is later cured of his corruption after Dark Samus' defeat later on. Between the "Prime" trilogy and "", the Space Pirates reorganize on Zebes and hatch another plan to clone and weaponize the Metroids, while Ridley gradually begins to regenerate from his past injuries, gradually shedding his cybernetics. In the remake of the second game, "", Ridley, in his semi-regenerated form of "Proteus Ridley", attacks Samus on SR388 to steal the last remaining Metroid. Samus and the baby Metroid work together to defeat Ridley.
Spider (pulp fiction)
Despite The Spider's tendency to kill his enemies, he encounters several foes more than once, such as The Fly and MUNRO, a master of disguise. Some storylines featuring a struggle against a single villain lasted for several consecutive issues, such as The Spider's four-part battle against The Living Pharaoh and The Spider's three-part battle against The Master and his Black Police. Among the enemies he encountered just once were predecessors of the costumed super villains of comic books, such as Judge Torture, Red Feather, The Bloody Serpent, The Brain, The Emperor of Vermin, The Red Mandarin, The Silencer, and The Wreck. The names of two Spider villains, The Bat Man and The Iron Man, were later adopted for DC and Marvel comic book superheroes.