Crema, Lombardy
By the 1859 Treaty of Zurich which ended the Austro-Sardinian War, Austria ceded Lombardy, including Crema, to France, who then immediately ceded it to Sardinia. This formed part of the "Risorgimento", which saw Sardinia become the Kingdom of Italy in 1861. In 1946, the Kingdom became the modern Italian Republic.
Grand Duchy of Tuscany
In December 1859, the Grand Duchy effectively ceased to exist, being joined to the Duchies of Modena and Parma to form the United Provinces of Central Italy, which were annexed by the Kingdom of Sardinia a few months later. On 22 March 1860, after a referendum that voted overwhelmingly (95%) in favour of a union with Sardinia; Tuscany was formally annexed to Sardinia. Italy was unified in 1870, when the remains of the Papal States were annexed in that September, deposing Pope Pius IX.