William I of Württemberg
On 24 January 1816, in Saint Petersburg, he married his first cousin, Grand Duchess Catherine Pavlovna of Russia (1788–1819), daughter of Emperor Paul I of Russia (1754–1801) and Princess Sophie Dorothea of Württemberg (1759–1828). The couple had two children:
Countess Palatine Dorothea Sophie of Neuburg
This marriage was decided by Francesco himself, because he didn't want to give up Dorothea's dowry should she marry someone else. Nevertheless, this marriage remained childless.