Han–Xiongnu War
In 119 BC, when the Xiongnu suffered a catastrophic defeat by the Han armies, the Chanyu moved his court (located in present-day Inner Mongolia) to another location north. This had the desired result that the Xiongnu were separated the Wuhuan people, which also prevented the Xiongnu from exacting many resources from the Wuhuan. The Han court placed the Wuhuan in tributary protection and resettled them in five northeastern commandaries, namely Shanggu, Yuyang, Youbeiping (present-day Hebei), Liaoxi, and Liaodong (present-day Liaoning). A new office, the Colonel-Protector of the Wuhuan, was established (near present-day Beijing) in order to prevent contact between the Wuhuan with the Xiongnu and to use them to monitor the Xiongnu activities. Nevertheless, the effective Han control over the Wuhuan was lacking through much of the Western Han period, since the Xiongnu had considerable military and political influence over the Wuhuan while relations between the Wuhuan and Han often remained strained at best. This can be exemplified by a situation in 78 BC, when the Xiongnu led a punitive campaign against the Wuhuan, resulting in General Fan Mingyou (范明友) leading a Han army to impede further incursions. When they learned that the Xiongnu had left by the time the army arrived, the Han court ordered Fan to attack the Wuhuan instead, killing 6000 Wuhuan men and three chieftains, since the Wuhuan had recently raided Han territory. Only in 49 AD, when 922 Wuhuan chieftains submitted during Emperor Guangwu's reign, did many of the Wuhuan tribes come under tributary system of the Han empire. The Han court provided for the Wuhuan and in return the Wuhuan tribes guarded the Han frontier against the Xiongnu and other nomadic peoples.
Han–Xiongnu War
In 25 AD, Liu Xiu was established as Emperor Guangwu, restoring the Han throne after a usurpation by the Han official Wang Mang, thus initiating the Eastern Han period. During his reign, the Han empire began to abandon its offensive strategy against the Xiongnu, which allowed the latter to frequently raid the northern frontier. It resulted in large migrations southwards, which led to the depopulation of the frontier regions. During the Eastern Han period, various nomadic peoples were resettled in these frontier regions, serving the Han empire as cavalry against the Xiongnu. With his primary focus still towards the interior of the empire, Emperor Guangwu declined several requests from the western states to reestablish the office of Protector-General of the Western Regions. Early in Emperor Guangwu's reign, King Kang of Yarkand united neighboring kingdoms to resist the Xiongnu. At the same time, he protected the Han officials and people of the former Protector-General, who were still left behind after Wang Mang's reign. In 61 AD, Yarkand was conquered by Khotan and the western states fell in conflict with each other. Taking this opportunity, the Northern Xiongnu recovered their control over the Western Regions, which threatened the security of the Hexi Corridor. In 73 AD, General Dou Gu was sent on a punitive expedition to the Xiongnu and inflicted them a considerable defeat. Immediately, the fertile lands of Hami (Yiwu) was reoccupied and an agricultural garrison established. The next year (74 AD), he expelled the Xiongnu from Turfan and reoccupied the state. The recovery of Hami and Turfan facilitated the reestablishment of the Protector-General, since these important locations were key points to control the Western Regions.