Osteoblastoma
When diagnosing osteoblastoma, the preliminary radiologic workup should consist of radiography of the site of the patient's pain. However, computed tomography (CT) is often necessary to support clinical and plain radiographic findings suggestive of osteoblastoma and to better define the margins of the lesion for potential surgery. CT scans are best used for the further characterization of the lesion with regard to the presence of a nidus and matrix mineralization. MRI aids in detection of nonspecific reactive marrow and soft tissue edema, and MRI best defines soft tissue extension, although this finding is not typical of osteoblastoma. Bone scintigraphy (bone scan) demonstrates abnormal radiotracer accumulation at the affected site, substantiating clinical suspicion, but this finding is not specific for osteoblastoma. In many patients, biopsy is necessary for confirmation.
Ultrasound computer tomography
USCT systems designed for medical imaging of soft tissue typically aim for resolution in order of centimeters to millimeters and require therefore ultrasound waves in the order of mega-hertz frequency. This requires typically water as low-attenuating transmission medium between ultrasound transducers and object to retain suitable sound pressures.