Old Isisford District Hospital
Starting in 1948 and continuing into the 1950s, extensions were made to Isisford Hospital including: a kitchen, operating theatre and an extension to one of the 1892 buildings. Blackall Hospitals Board was advised by the Department of Health and Home Affairs that its plan for remodelling the Isisford Hospital had been approved; there was also approval for installation of an X-ray plant at Isisford.
Old Isisford District Hospital
In the twenty-first century, a further reduction of services to the region occurred with the closure of the Jericho-Yaraka railway line and its replacement with sealed road from Blackall to Windorah. Queensland Rail ceased operations on the Yaraka line in November of the same year. In 2006 Isisford's population was 262 - its level in the 1960s and 1970s.