Muhammad
Muhammad's life is traditionally defined into two periods: pre-hijra (emigration) in Mecca (from 570 to 622), and post-hijra in Medina (from 622 until 632). Muhammad is said to have had thirteen wives in total (although two have ambiguous accounts, Rayhana bint Zayd and Maria al-Qibtiyya, as wife or concubine.) Eleven of the thirteen marriages occurred after the migration to Medina.
Mecca
It has been reported that there are now fewer than 20 structures remaining in Mecca that date back to the time of Muhammad. Other buildings that have been destroyed include the house of Khadijah, the wife of Muhammad, demolished to make way for public lavatories; the house of Abu Bakr, Muhammad's companion, now the site of the local Hilton hotel; the house of Muhammad's grandson Ali-Oraid and the Mosque of abu-Qubais, now the location of the King's palace in Mecca; Muhammad's birthplace, demolished to make way for a library; and the Ottoman-era Ajyad Fortress, demolished for construction of the Abraj Al Bait Towers.