Muhammad
Muhammad's life is traditionally defined into two periods: pre-hijra (emigration) in Mecca (from 570 to 622), and post-hijra in Medina (from 622 until 632). Muhammad is said to have had thirteen wives in total (although two have ambiguous accounts, Rayhana bint Zayd and Maria al-Qibtiyya, as wife or concubine.) Eleven of the thirteen marriages occurred after the migration to Medina.
Muhammad in Mecca
Muhammad consented to the marriage, which by all accounts was a happy one. Khadija was not only Muhammad's wife, but also his friend and confidante and later his moral support. After his wedding, Khadija gave Muhammad the slave boy Zayd ibn Harithah. Ibn Ishaq records that Khadijah bore Muhammad six children: a boy named Qasim, who lived only two years, then four girls Zaynab, Ruqayyah, Um Kulthum, Fatimah and finally a boy named Abdullah, who also died at two. According to some Shi'a scholars, Fatimah was Muhammad's only daughter. The combination of the death of Abdullah, and his desire to relieve his uncle Abu Talib of the burden of a large family, as Abu Talib was already in great financial difficulty, led Muhammad to take his uncle's son Ali into his own home. Muhammad also adopted Zayd, giving him the name "Zayd ibn Muhammad" (meaning Zayd son of Muhammad). However, owing to the adoption revelation from Allah, later verses were revealed stating clearly that a child, especially after adoption, could not be treated as a natural son by marriage or inheritance. Consequently, the adopted child had to retain the name of his or her biological father. Therefore, Zayd could not be known as the son of Muhammad, but the son of his father, Haritha, and be known as Zayd ibn Haritha. In Quran : 33:40 "40. Muhammad is not the father of any man among you, but he is the Messenger of Allâh and the last of the Prophets. And Allâh is Ever All-Aware of everything. "