WUTV
On December 6, 2017, it was reported that Sinclair and Fox were working on a deal that would see its Fox affiliates renew their affiliation agreement in exchange for Sinclair selling some of its Fox affiliates directly to Fox Television Stations. The deal would see between six and ten Fox affiliates owned by Sinclair and Tribune (all in markets with an NFL team) become Fox owned-and-operated stations. It is not known if WUTV will be one of the stations sold, although the stations being sold to Fox are expected to be from Tribune Media (notably KCPQ in Seattle, where Sinclair already owns KOMO-TV), many of which were previously owned by Fox. A sale to Fox would make WUTV Buffalo's first Big Four network O&O since WBUF-TV (channel 17, now PBS member WNED-TV), which was owned by NBC from 1955 until its sign-off in 1958. On May 9, 2018, Sinclair announced that seven Fox affiliates would be sold to FTS, but WUTV was not included and an affiliation renewal was announced for that station instead, keeping WUTV with Sinclair.
WTHI-TV
On August 25, 2011, it was announced that WTHI had signed affiliation agreements with Fox and MyNetworkTV, which both began broadcasting on WTHI's second digital subchannel on September 1, 2011; WFXW (now WAWV-TV), which had been the market's original Fox affiliate since it switched to the network from ABC in January 1995, rejoined ABC on that date in concurrence with a dispute between management partner Nexstar Broadcasting Group and Fox as well as an affiliation renewal deal with ABC for the company's other affiliates of that network. WTHI-TV became the third LIN Media station to carry major network affiliations on both the main channel and a digital subchannel (LIN-owned NBC affiliate WOOD-TV in Grand Rapids, Michigan and Fox affiliate WNAC-TV in Providence, Rhode Island, the latter of which is owned by Super Towers, Inc. and operated by LIN, both carry MyNetworkTV on a second digital subchannel).