Madelyne Pryor
Madelyne Pryor was introduced during the acclaimed 1983 "Uncanny X-Men" run that saw long-time writer Chris Claremont pair with artist Paul Smith for a series of issues that would see the Jean Grey look-alike marry the retired X-Men leader Scott Summers (Cyclops).
Aunt May
The character has appeared in most other media adaptations of the comics, often playing a prominent role. She has been adapted for other media numerous times, including: Jeff Donnell in 1977, Irene Tedrow in the weekly Amazing Spider-Man television series, Rosemary Harris in Sam Raimi's "Spider-Man" trilogy, Sally Field in Marc Webb's "The Amazing Spider-Man" duology, Marisa Tomei in the Marvel Cinematic Universe, and Lily Tomlin in "".