Twenty-second Amendment to the United States Constitution
As worded, the primary focus of the 22nd Amendment is on limiting individuals twice elected to the presidency from being elected again. Due to this, several issues could be raised regarding the amendment's meaning and application, especially in relation to the 12th Amendment, ratified in 1804, which states, "But no person constitutionally ineligible to the office of President shall be eligible to that of Vice-President of the United States". While it is clear that under the 12th Amendment the original constitutional qualifications of age, citizenship, and residency apply to both the president and vice president, it is unclear whether someone who is ineligible to be elected president could be elected vice president. Because of this apparent ambiguity, there may be a loophole in the 22nd Amendment whereby a two-term former-president could be elected vice president and then succeed to the presidency as a result of the incumbent's death, resignation, or removal from office (or even succeed to the presidency from some other stated office in the presidential line of succession).
2008 United States presidential election
Incumbent Republican President George W. Bush was ineligible to pursue a third term due to the term limits established by the 22nd Amendment. As neither Bush nor Vice President Dick Cheney sought the presidency, the 2008 election was the first election since 1952 in which neither major party's presidential nominee was the incumbent president or the incumbent vice president. McCain secured the Republican nomination by March 2008, defeating Mitt Romney, Mike Huckabee, and other challengers. The Democratic primaries were marked by a sharp contest between Obama and the initial front-runner, Senator Hillary Clinton. Clinton's victory in the New Hampshire primary made her the first woman to win a major party's presidential primary. After a long primary season, Obama clinched the Democratic nomination in June 2008.