Manuel I of Portugal
Manuel's mother was the granddaughter of King John I of Portugal, whereas his father was the second surviving son of King Edward of Portugal and the younger brother of King Afonso V of Portugal. In 1495, Manuel succeeded his first cousin, King John II of Portugal, who was also his brother-in-law, as husband to Manuel's sister, Eleanor of Viseu.
Manuel de Moura Corte Real, 2nd Marquis of Castelo Rodrigo
Manuel entered the service of the Habsburg crown in 1615 as Gentleman of the Chamber of the future Philip III of Portugal. When the prince succeeded to the throne as Philip IV in 1621, Castelo Rodrigo was kept on the sidelines by his jealous rival Gaspar de Guzmán, Count-Duke of Olivares, still insecure in his position as favorite.