Trench foot
The mainstay of treatment, like the treatment of gangrene, is surgical debridement, and often includes amputation. Self-treatment consists of changing socks two or three times a day and usage of plenty of talcum powder. Wherever possible, shoes and socks should be taken off, feet bathed for five minutes, patted dry, talcum powder applied and feet elevated to let air get to them.
Stem-cell therapy
Stem cells have been used to treat degenerative bone diseases. The normally recommended treatment for dogs that have Legg–Calve–Perthes disease is to remove the head of the femur after the degeneration has progressed. Recently, mesenchymal stem cells have been injected directly in to the head of the femur, with success not only in bone regeneration, but also in pain reduction.