Early modern period
In the early modern period, the Holy Roman Empire was a union of territories in Central Europe under a Holy Roman Emperor the first of which was Otto I. The last was Francis II, who abdicated and dissolved the Empire in 1806 during the Napoleonic Wars. Despite its name, for much of its history the Empire did not include Rome within its borders.
Maria Theresa of Naples and Sicily
Maria Theresa of Naples and Sicily (6 June 1772 – 13 April 1807) was the last Holy Roman Empress and the first Empress of Austria by marriage to Francis II, Holy Roman Emperor. She was the eldest daughter of Ferdinand IV & III of Naples and Sicily (later Ferdinand I of the Two Sicilies) (1751–1825) and Marie Caroline of Austria (1752–1814).