Anterior cingulate cortex
It appears to play a role in a wide variety of autonomic functions, such as regulating blood pressure and heart rate.
Bilateral cingulotomy
Functional MRI analyses of the anterior cingulate cortex have also led to the introduction of bilateral cingulotomy for the treatment of chronic pain. Such application was introduced since the anterior cingulate cortex has been found to be related to the processing nociceptive information input. In particular the role of the anterior cingulate cortex is in the interpretation of how a stimulus affects a person rather than its actual physical intensity.