Astronaut
The first civilian in space was Valentina Tereshkova aboard Vostok 6 (she also became the first woman in space on that mission).
Tereshkova was only honorarily inducted into the USSR's Air Force, which did not accept female pilots at that time. A month later, Joseph Albert Walker became the first American civilian in space when his X-15 Flight 90 crossed the line, qualifying him by the international definition of spaceflight. Walker had joined the US Army Air Force but was not a member during his flight. 
The first people in space who had never been a member of any country's armed forces were both Konstantin Feoktistov and Boris Yegorov aboard Voskhod 1.
Kalpana Chawla
Kalpana Chawla (March 17, 1962 – February 1, 2003) was an American astronaut, engineer and the first female of Indian origin to go to space. She first flew on Space Shuttle "Columbia" in 1997 as a mission specialist and primary robotic arm operator. In 2003, Chawla was one of the seven crew members who died in the Space Shuttle "Columbia" disaster when the aircraft disintegrated during its re-entry into the Earth's atmosphere. Chawla was posthumously awarded the Congressional Space Medal of Honor, and several streets, universities and institutions have been named in her honor.