Florida Territory
Beginning in late 1835, Osceola and the Seminole allies began a guerrilla war against the U.S. forces. Numerous generals fought and failed, succumbing to the heat and disease as well as lack of knowledge of the land. It was not until General Thomas Jesup captured many of the key Seminole chiefs, including Osceola who died in captivity of illness, that the battles began to die down. The Seminoles were eventually forced to migrate. Florida joined the Union as the 27th state on March 3, 1845. By this time, almost all of the Seminoles were gone, except for a small group living in the Everglades.
Territorial evolution of the United States
Desires for expansion into Spanish territories like Cuba led to the Spanish–American War in 1898, in which the United States gained Guam, Puerto Rico, and the Philippines, and occupied Cuba for several years. American Samoa was acquired by the United States in 1900 after the end of the Second Samoan Civil War. The United States purchased the U.S. Virgin Islands from Denmark in 1917. Guam and Puerto Rico remain territories; the Philippines became independent in 1946, after being a major theater of World War II. Following the war, many islands were entrusted to the U.S. by the United Nations, and while the Northern Mariana Islands remain a U.S. territory, the Marshall Islands, Federated States of Micronesia, and Palau emerged from the trust territory as independent nations. The last major international change was the acquisition in 1904, and return to Panama in 1979, of the Panama Canal Zone, a region of American sovereignty to build and run the Panama Canal. The final cession of power over the region was made to Panama in 1999.