Anterior cingulate cortex
It appears to play a role in a wide variety of autonomic functions, such as regulating blood pressure and heart rate.
Psychosurgery
Anterior cingulotomy was first used by Hugh Cairns in the UK, and developed in the US by H.T. Ballantine jnr. In recent decades it has been the most commonly used psychosurgical procedure in the US. The target site is the anterior cingulate cortex; the operation disconnects the thalamic and posterior frontal regions and damages the anterior cingulate region.