Inland taipan
The inland taipan is the most venomous snake in the world. Based on the median lethal dose value in mice, its venom, drop for drop, is by far the most toxic of any snake – much more so than even sea snakes – and it has the most toxic venom of any reptile when tested on human heart cell culture. Unlike most snakes, the inland taipan is a specialist mammal hunter so its venom is specially adapted to kill warm-blooded species. It is estimated that one bite possesses enough lethality to kill at least 100 fully grown men, and, depending on the nature of the bite, it has the potential to kill someone in as little as 30 to 45 minutes if left untreated. It is an extremely fast and agile snake that can strike instantly with extreme accuracy, often striking multiple times in the same attack, and it envenoms in almost every case.
List of dangerous snakes
The Puff adder ("Bitis arietans") is responsible for more fatalities than any other African snake. This is due to a combination of factors, including its wide distribution, common occurrence, large size, potent venom that is produced in large amounts, long fangs, their habit of basking by footpaths and sitting quietly when approached. The venom has cytotoxic effects and is one of the most toxic of any vipers based on LD50 studies. The values in mice vary: 0.4–2.0 mg/kg IV, 0.9–3.7 mg/kg IP, 4.4–7.7 mg/kg SC. Mallow et al. (2003) gives a LD range of 1.0–7.75 mg/kg SC. Venom yield is typically between 100–350 mg, with a maximum of 750 mg. Brown (1973) mentions a venom yield of 180–750 mg. About 100 mg is thought to be enough to kill a healthy adult human male, with death occurring after 25 hours. In humans, bites from this species can produce severe local and systemic symptoms. Based on the degree and type of local effect, bites can be divided into two symptomatic categories: those with little or no surface extravasation, and those with hemorrhages evident as ecchymosis, bleeding and swelling. In both cases there is severe pain and tenderness, but in the latter there is widespread superficial or deep necrosis and compartment syndrome. Serious bites cause limbs to become immovably flexed as a result of significant hemorrhage or coagulation in the affected muscles. Residual induration, however, is rare and usually these areas completely resolve. The fatality rate depends on the severity of the bites and some other factors. Deaths are rare and occur in less than 10% of all untreated cases (usually in 2–4 days from complications following blood volume deficit and a disseminated intravascular coagulopathy), although some reports show that very severe envenomations have a 52% mortality rate. Most fatalities are associated with bad clinical management and neglect.