Florida Territory
Beginning in late 1835, Osceola and the Seminole allies began a guerrilla war against the U.S. forces. Numerous generals fought and failed, succumbing to the heat and disease as well as lack of knowledge of the land. It was not until General Thomas Jesup captured many of the key Seminole chiefs, including Osceola who died in captivity of illness, that the battles began to die down. The Seminoles were eventually forced to migrate. Florida joined the Union as the 27th state on March 3, 1845. By this time, almost all of the Seminoles were gone, except for a small group living in the Everglades.
Florida
On January 10, 1861, nearly all delegates in the Florida Legislature approved an ordinance of secession, declaring Florida to be "a sovereign and independent nation"—an apparent reassertion to the preamble in Florida's Constitution of 1838, in which Florida agreed with Congress to be a "Free and Independent State." Although not directly related to the issue of slavery, the ordinance declared Florida's secession from the Union, allowing it to become one of the founding members of the Confederate States, a looser union of states.