Siouan languages
Siouan or Siouan–Catawban is a language family of North America that is located primarily in the Great Plains, Ohio and Mississippi valleys and southeastern North America with a few other languages in the east.
Ohio Valley Siouan languages
They are called "Ohio Valley Siouan" languages because of a speculative origin along the Ohio River, but only the Tutelo and the Saponi historically dwelled near there; they possibly migrated to the Roanoke River from the region of the Big Sandy River just prior to European contact. The Biloxi and the Ofo lived far to the south, along the Mississippi River.