Traumatic Brain Injury Reauthorization Act of 2013
The Traumatic Brain Injury Reauthorization Act of 2013 would amend the Public Health Service Act to reauthorize appropriations for FY2014-FY2018 for: (1) Centers for Disease Control and Prevention (CDC) projects to reduce the incidence of traumatic brain injury, and (2) traumatic brain injury surveillance systems or registries.
Glutamate carboxypeptidase II
Severe head injury (SHI) and traumatic brain injury (TBI) are widespread and have a tremendous impact. “They are the leading cause of death in children and young adults (<25 years) and account for a quarter of all deaths in the five to 15 years age group”. Following initial impact, glutamate levels rise and cause excitotoxic damage in a process that has been well characterized. With its ability to reduce glutamate levels, NAAG inhibition has shown promise in preventing neurological damage associated with SHI and TBI.