Muhammad
Muhammad's life is traditionally defined into two periods: pre-hijra (emigration) in Mecca (from 570 to 622), and post-hijra in Medina (from 622 until 632). Muhammad is said to have had thirteen wives in total (although two have ambiguous accounts, Rayhana bint Zayd and Maria al-Qibtiyya, as wife or concubine.) Eleven of the thirteen marriages occurred after the migration to Medina.
Fatimah
Modern descendants of Muhammad trace their lineage exclusively through Fatimah, as she was the only surviving child of Muhammad (According to Shias. Sunni and some Shia believe Muhammad had 4 daughters). Muhammad had no sons who reached adulthood.