Basal-cell carcinoma
In the United States approximately 3 out of 10 caucasians develop a basal-cell carcinoma during their lifetime. This tumor accounts for approximately 70% of non-melanoma skin cancers. In 80 percent of all cases, basal-cell carcinoma affects the skin of head and neck. Furthermore, there appears to be an increase in the incidence of basal-cell cancer of the trunk in recent years.
Basaloid squamous cell lung carcinoma
Both basaloid and squamous cell carcinomas have been shown to arise from pre-malignant lesions of dysplasia in the airways of the lung. After continued exposure to tobacco smoke or other carcinogenic stimuli, cells in areas of severe dysplasia can suffer additional genetic damage that results in progression to a basaloid or squamous cell carcinoma "in situ" (CIS). CIS is a fully malignant lesion, but by definition, the cancer cells have not yet invaded beyond the tissue delimiting their original site of genesis.