Botulinum toxin
In 1895 (seventy-five years later), Émile van Ermengem, professor of bacteriology and a student of Robert Koch, correctly described "Clostridium botulinum" as the bacterial source of the toxin. Thirty-four attendees at a funeral were poisoned by eating partially salted ham, an extract of which was found to cause botulism-like paralysis in laboratory animals. Van Ermengem isolated and grew the bacterium, and described its toxin, which was later purified by P Tessmer Snipe and Hermann Sommer.
AB5 toxin
This family is also known as Ptx and contains the toxin responsible for whooping cough. Pertussis toxin is secreted by the gram-negative bacterium, "Bordetella pertussis". Whooping cough is very contagious and cases are slowly increasing in the United States despite vaccination. Symptoms include paroxysmal cough with whooping and even vomiting. The bacterium "Bordetella pertussis" was first identified as the cause of whooping cough and isolated by Jules Bordet and Octave Gengou in France in 1900.