Muhammad
Muhammad's life is traditionally defined into two periods: pre-hijra (emigration) in Mecca (from 570 to 622), and post-hijra in Medina (from 622 until 632). Muhammad is said to have had thirteen wives in total (although two have ambiguous accounts, Rayhana bint Zayd and Maria al-Qibtiyya, as wife or concubine.) Eleven of the thirteen marriages occurred after the migration to Medina.
Women in the Quran
Sura 33:32-34 declare that women of prophet are not like other women and so specifies special ettiquettes for them. 
The Prophet, Muhammad, had four daughters with his wife, Khadija bint Khuwaylid: Zainab, Umm Kulthum, Ruqayyah, and Fatimah; however, Shias believe Fatima was the only daughter of Khadija and Zainab, Ruqayya and Umm Kulthum were the daughters of Khadija's sister, Hala. Fatima is held on the same level as Mary in the Shia tradition, and is referred to as the "mistress of sorrows."