Testicular immunology
Mumps is a viral disease which causes swelling of the salivary glands and testes. The mumps virus lives in the upper respiratory tract and spreads through direct contact with saliva. Prior to widespread vaccination programs, it was a common childhood disease. Mumps is generally not serious in children, but in adults, where sperm have matured in the testis, it can cause more severe complications, such as infertility.
Prenatal development
If a mother is infected with a disease, the placenta cannot always filter out pathogens. Viruses such as rubella, chicken pox, mumps, herpes, and human immunodeficiency (HIV) are associated with increased risk of miscarriage, low birth weight, and prematurity, physical malformations, and intellectual disabilities. The human immunodeficiency virus can lead to acquired immune deficiency syndrome (AIDS). Untreated HIV infected expectant mothers pass the virus to their developing offspring between 10 and 20 percent of the time. . Expectant mothers infected with bacterial or parasitic diseases may also pass the diseases on to the fetus. Examples of diseases include chlamydia, syphilis, tuberculosis, malaria, and toxoplasmosis. One of the most common of these diseases is toxoplasmosis. A pregnant female may become infected through contact with contaminated soil, such as through gardening, eating raw or undercooked meat or unwashed vegetables or fruits, or contact with the feces of infected cats. If the exposure occurs during the first trimester, eye and brain damage may result. Exposure later in pregnancy may result in mild visual and cognitive impairments.