Ridley (Metroid)
Ridley returns in his Meta form once again in "", where he, along with the Space Pirate legion under his command, are corrupted by Dark Samus. He encounters and battles Samus on Norion, a Galactic Federation-occupied world, and the two fight while free-falling down an air shaft. Ridley is later supercharged with Phazon, becoming "Omega Ridley", and is charged with guarding the Leviathan Seed on the Space Pirate homeworld. He is confronted once again by Samus, and despite being defeated, he survives the fight and is later cured of his corruption after Dark Samus' defeat later on. Between the "Prime" trilogy and "", the Space Pirates reorganize on Zebes and hatch another plan to clone and weaponize the Metroids, while Ridley gradually begins to regenerate from his past injuries, gradually shedding his cybernetics. In the remake of the second game, "", Ridley, in his semi-regenerated form of "Proteus Ridley", attacks Samus on SR388 to steal the last remaining Metroid. Samus and the baby Metroid work together to defeat Ridley.
Mother Brain
The Boston Phoenix editors Ryan Stewart and Mitch Krpata named Mother Brain the fourth greatest boss in video game history, stating that while she had triumphant roles in "Metroid" and "Captain N", she didn't come into her own until "Super Metroid". They cited the overall quality of the ending for why she was so notable in this role. GameDaily listed Mother Brain as the 12th best evil mastermind in video games. GamesRadar editor David Houghton listed Mother Brain as one gaming's most hideous mums, describing her as looking like a "turd on a stick jammed into the top of a long-dead chicken." In explaining why "Metroid" was among gaming's greatest games, GameSpot editor Avery Score cited the battles with Mother Brain and Kraid, describing the battles as epic. Fellow GameSpot editor Giancarlo Varanini described Mother Brain as "appropriately disgusting". GamePro listed Mother Brain as the sixth most diabolical video game villain, describing the battle with her as one of the most notorious and epic assaults in gaming history. UGO.com listed Mother Brain as one of the runners-up for the "Miss Entertainment", commenting that she has sadly diminished in her attempts to thwart Samus, though they hope that she returns. Mother Brain is also featured in the ongoing GameSpot's All-time greatest game villain. In 2011, "Complex" ranked her as sixth on the list of "most diabolical video game she-villains".