Wicked Witch of the West
The Wicked Witch appears as the main antagonist of the second half of Season Three of "Once Upon a Time" played by Rebecca Mader. This version goes by the name of Zelena (which means "green" in some Slavic languages). Zelena is discovered to be the daughter of the Queen of Hearts/the Miller's Daughter/Cora (Barbara Hershey/Rose McGowan), making her the older, long-lost half-sister of Regina the Evil Queen (Lana Parrilla). Zelena visited Rumplestiltskin (Robert Carlyle) and learned from him how to control her own powerful magic. Her storyline revolves around her efforts to create a time-travel spell that will allow her to go back and prevent the birth of Snow White's mother, Ava, who informed Prince Leopold (Cora's fiancé) that Cora was with child to sabotage Cora's attempts to infiltrate the royal family (before she can ruin Zelena's life, and thus Zelena would be raised as royalty. But despite Zelena's efforts to create the deadly time portal Emma Swan (supposedly the only wielder of light magic powerful enough to oppose her) her plans are halted when the Evil Queen masters light magic in time to oppose her (although her time-travel spell is completed, it takes effect after her presumed death, transporting Emma and Captain Hook (Colin O'Donoghue) back to before the original curse was cast). She was later thought to have been killed by Rumpelstiltskin.
Portrayals of Alice in Wonderland
Alice is the central character in the 2013 fantasy series "Once Upon a Time in Wonderland" (a spin-off to "Once Upon a Time") portrayed by Sophie Lowe. The story is set in a fictional Victorian England-theme world and takes place after Alice has returned from Wonderland. Due to the stories she tells about the hookah-smoking caterpillar and Cyrus, played by Peter Gadiot, the genie she fell in love with and believed to be dead, she is declared insane and placed in London’s Bethlem Asylum. The doctors decide that the best treatment for Alice is a procedure that will make her forget Wonderland and all of the events that happened there. Alice, wanting to forget her painful past, agrees to the procedure. The night before the procedure, the White Rabbit, voiced by John Lithgow, and the Knave of Hearts, played by Michael Socha arrive in the asylum and tell Alice that Cyrus is not dead but may be in danger. Hearing this, Alice agrees to go back to Wonderland and help find her true love. It is later revealed that Cyrus is being held prisoner by Jafar (played by Naveen Andrews) who wants to use Cyrus’ magic to take over Wonderland and who is also working with the evil Red Queen (played by Emma Rigby). 
Throughout the series, Alice and the Knave of Hearts work together to try and rescue Cyrus and stop the Red Queen and Jafar from wrecking more havoc in Wonderland.