Basal-cell carcinoma
Basal-cell cancer is a very common skin cancer. It is much more common in fair-skinned individuals with a family history of basal-cell cancer and increases in incidence closer to the equator or at higher altitude. There are approximately 800,000 new cases yearly in the United States alone. Up to 30% of Caucasians develop basal-cell carcinomas in their lifetime. In Canada, the most common skin cancer is basal-cell carcinoma (as much as one third of all cancer diagnoses), affecting 1 in 7 individuals over a lifetime.
Squamous-cell carcinoma of the lung
Currently, four variants (papillary, small-cell, clear-cell, and basaloid) of squamous-cell carcinoma of the lung are recognized. Of these variants, there is some evidence that the basaloid and poorly differentiated small-cell variants may have worse prognoses than "conventional" squamous-cell carcinomas. The papillary variant occurs more frequently as a primarily superficial, endobronchial lesion, with a modestly better prognosis Very little data is currently available on the clear-cell variant of squamous-cell carcinoma, and no consensus has been reached on the prognostic implications of clear-cell changes in lung cancer.