Twenty-second Amendment to the United States Constitution
As worded, the primary focus of the 22nd Amendment is on limiting individuals twice elected to the presidency from being elected again. Due to this, several issues could be raised regarding the amendment's meaning and application, especially in relation to the 12th Amendment, ratified in 1804, which states, "But no person constitutionally ineligible to the office of President shall be eligible to that of Vice-President of the United States". While it is clear that under the 12th Amendment the original constitutional qualifications of age, citizenship, and residency apply to both the president and vice president, it is unclear whether someone who is ineligible to be elected president could be elected vice president. Because of this apparent ambiguity, there may be a loophole in the 22nd Amendment whereby a two-term former-president could be elected vice president and then succeed to the presidency as a result of the incumbent's death, resignation, or removal from office (or even succeed to the presidency from some other stated office in the presidential line of succession).
Rob Portman
In March 2014, Larry Sabato of the University of Virginia Center for Politics speculated that Portman might run for president in 2016. Sabato forecasted: "[Portman] might have an edge in 2016. Americans tire of their incumbent presidents, and often choose a very different successor with dissimilar characteristics. Portman is all steak and no sizzle." In October 2014, students from the College of William and Mary formed the Draft Rob Portman PAC to encourage Portman to run for president in 2016. However, Portman announced in December 2014 that he would not run for president and would instead seek a second term in the United States Senate.
Portman and Senator Ben Cardin (D-Maryland) proposed the Israel Anti-Boycott Act in late 2018 which would make it illegal for companies to engage in boycotts against Israel. Cardin and Portman have been strongly in promotion of the bill, working to integrate it into larger spending legislation to be signed by President Trump.