Mass
In everyday usage, mass and "weight" are often used interchangeably. For instance, a person's weight may be stated as 75 kg. In a constant gravitational field, the weight of an object is proportional to its mass, and it is unproblematic to use the same unit for both concepts. But because of slight differences in the strength of the Earth's gravitational field at different places, the distinction becomes important for measurements with a precision better than a few percent, and for places far from the surface of the Earth, such as in space or on other planets. Conceptually, "mass" (measured in kilograms) refers to an intrinsic property of an object, whereas "weight" (measured in newtons) measures an object's resistance to deviating from its natural course of free fall, which can be influenced by the nearby gravitational field. No matter how strong the gravitational field, objects in free fall are weightless, though they still have mass.
Mass in special relativity
It is often convenient in calculation that the invariant mass of a system is the total energy of the system (divided by "c") in the COM frame (where, by definition, the momentum of the system is zero). However, since the invariant mass of any system is also the same quantity in all inertial frames, it is a quantity often calculated from the total energy in the COM frame, then used to calculate system energies and momenta in other frames where the momenta are not zero, and the system total energy will necessarily be a different quantity than in the COM frame. As with energy and momentum, the invariant mass of a system cannot be destroyed or changed, and it is thus conserved, so long as the system is closed to all influences. (The technical term is isolated system meaning that an idealized boundary is drawn around the system, and no mass/energy is allowed across it.)