Disk encryption software
Disk encryption generally refers to wholesale encryption that operates on an entire volume mostly transparently to the user, the system, and applications. This is generally distinguished from file-level encryption that operates by user invocation on a single file or group of files, and which requires the user to decide which specific files should be encrypted. Disk encryption usually includes all aspects of the disk, including directories, so that an adversary cannot determine content, name or size of any file. It is well suited to portable devices such as laptop computers and thumb drives which are particularly susceptible to being lost or stolen. If used properly, someone finding a lost device cannot penetrate actual data, or even know what files might be present.
Email encryption
The encrypted message is revealed to, and can be altered by, intermediate email relays. In other words, the encryption takes place between individual SMTP relays, not between the sender and the recipient. This has both good and bad consequences. A key positive trait of transport layer encryption is that users do not need to do or change anything; the encryption automatically occurs when they send email. In addition, since receiving organizations can decrypt the email without cooperation of the end user, receiving organizations can run virus scanners and spam filters before delivering the email to the recipient. However, it also means that the receiving organization and anyone who breaks into that organization's email system (unless further steps are taken) can easily read or modify the email. If the receiving organization is considered a threat, then end-to-end encryption is necessary.