Manuel I of Portugal
Manuel's mother was the granddaughter of King John I of Portugal, whereas his father was the second surviving son of King Edward of Portugal and the younger brother of King Afonso V of Portugal. In 1495, Manuel succeeded his first cousin, King John II of Portugal, who was also his brother-in-law, as husband to Manuel's sister, Eleanor of Viseu.
House of Braganza
King Carlos I was assassinated in 1908 together with his eldest son, D. Luís Filipe, Prince Royal of Portugal and Duke of Braganza, by republicans. His younger son, D. Manuel, Duke of Beja, survived the attack on his father and elder brother and became king as Manuel II, but was toppled two years later in the 1910 republican revolution. After the revolution, Manuel was forced into exile in England by the Portuguese First Republic, but he would continue to support his fatherland until his death.