When was the last smallpox outbreak?
1972 Yugoslav smallpox outbreak
The 1972 Yugoslav smallpox outbreak was the last major outbreak of smallpox in Europe. It was centred in Kosovo and Belgrade (both then part of the Socialist Federal Republic of Yugoslavia). A Muslim pilgrim had contracted the smallpox virus in the Middle East. Upon returning to his home in Kosovo, he started the epidemic in which 175 people were infected, 35 of whom died. The epidemic was efficiently contained by enforced quarantine and mass vaccination. The 1982 film "Variola Vera" is based on the event.
History of smallpox in Mexico
There were sporadic outbreaks until 1826 when smallpox appeared in Yucatán, Tabasco and Veracruz brought by North American ships. In 1828, there were reported cases in Hidalgo, Oaxaca, State of Mexico, Guerrero, Chiapas, Chihuahua and Mexico City.