Can you cure orientia tsutsugamushi?
Orientia tsutsugamushi
"O. tsutsugamushi" is naturally maintained in the mite population by transmission from female to its eggs (transovarial transmission), and from the eggs to larvae and then to adults (transtadial transmission). The mite larvae, called chiggers, are natural ectoparasites of rodents. Humans get infected upon accidental contact with infected chiggers. A scar-like scab called eschar is a good indicator of infection, but is not ubiquitous. The bacterium is endemic to the so-called Tsutsugamushi Triangle, a region covering the Russian Far East in the north, Japan in the east, northern Australia in the south, and Afghanistan in the west. One million infections are estimated to occur annually. Antibiotics such as azithromycin and doxycycline are the main prescription drugs; chloramphenicol and tetracyclin are also effective. Diagnosis of the infection is difficult and requires laborious techniques such as Weil–Felix test, rapid immunochromatographic test, immunofluorescence assays, and polymerase chain reaction. There is no working vaccine.
Pustulosis palmaris et plantaris
Several treatments are used to improve the symptoms of palmoplantar pustulosis. Oral acitretin is found to be effective especially in combination with psoralens and ultraviolet radiation (PUVA) treatment. Other treatments include oral ciclosporin and tetracycline antibiotics.