Raymond Damadian
Damadian received a National Medal of Technology in 1988 and was inducted into the National Inventors Hall of Fame in 1989. His original MRI full-body scanner was given to the Smithsonian Institution in the 1980s and is now on loan and on display at the National Inventors Hall of Fame in Ohio. In 2001, the Lemelson-MIT Prize Program bestowed its $100,000 Lifetime Achievement Award on Damadian as "the man who invented the MRI scanner."
Mass spectrometry imaging
More than 50 years ago, IMS was introduced using secondary ion mass spectrometry (SIMS) to study semiconductor surfaces by Castaing and Slodzian. However, it was the pioneering work of Richard Caprioli and colleagues in the late 1990s, demostrating how matrix-assisted laser desorption/ionization (MALDI) could be applied to visualize large biomolecules (as proteins and lipids) in cells and tissue to reveal the function of these molecules and how function is changed by diseases like cancer, which led to the widespread use of IMS. Nowadays, different ionization techniques have been used, including SIMS, MALDI and desorption electrospray ionization (DESI), as well as other technologies. Still, MALDI is the current dominant technology with regard to clinical and biological applications of MSI.