Liver cancer
Globally, , liver cancer resulted in 754,000 deaths, up from 460,000 in 1990, making it the third leading cause of cancer death after lung and stomach. In 2012, it represented 7% of cancer diagnoses in men, the 5th most diagnosed cancer that year. Of these deaths 340,000 were secondary to hepatitis B, 196,000 were secondary to hepatitis C, and 150,000 were secondary to alcohol. HCC, the most common form of liver cancer, shows a striking geographical distribution. China has 50% of HCC cases globally, and more than 80% of total cases occur in sub-Saharan Africa or in East-Asia due to hepatitis B virus. Cholangiocarcinoma also has a significant geographical distribution, with Thailand showing the highest rates worldwide due to the presence of liver fluke.
Sirtex
Primary liver cancer, or hepatocellular carcinoma (HCC) is the most common form of liver cancer, responsible for about 90% of the primary malignant liver tumours in adults. Liver cancer is the sixth most common cancer in the world and the third leading cause of cancer-related deaths globally. More than 600,000 cases of liver cancer are diagnosed worldwide each year. This comprises approximately 19,000 in the US, 54,000 in Europe and 390,000 in China, Korea and Japan. The incidence of HCC is increasing due to increased rates of chronic infection with Hepatitis B and Hepatitis C in Asia. Other risk factors include iron overload, alcoholic cirrhosis and some congenital disorders. Five year survival rates for liver cancer patients are low relative to other cancers.