Fonar Corp. v. General Electric Co.
"Fonar" was a dispute between medical device manufacturer Fonar Corporation and General Electric over Fonar's patent on MRI technology. Fonar's founder, Raymond Damadian, was issued U.S. Patent 3,789,832 (priority date 1972-03-17) for an "apparatus and method for detecting cancer in tissue" using the magnetic resonance of atoms. Damadian's patent was the first patent on an MRI machine issued in the United States. Also at issue was a later patent, U.S. Patent 4,871,966 issued in 1989, covering a method for obtaining MRI images of multiple planes at different orientations in a single scan. GE is a major manufacturer of MRI scanners, and Fonar sued GE for infringing these patents by producing its scanners as well as inducing others to infringe.
Vasilis Ntziachristos
Another focus of Ntziachristos' research is developing optoacoustic techniques for breaking thought the penetration barriers of conventional optical imaging methods. His group develops hardware, image reconstruction, spectral unmixing and information processing techniques as well as applications in biology and medicine. Among many other inventions, he is the inventor of multispectral optoacoustic tomography (MSOT) and raster scan optoacoustic mesoscopy (RSOM), which are non-invasive imaging methods that simultaneously measure different parameters of tissue physiology and pathology non-invasively, allowing new ways to diagnose disease and monitor treatment. MSOT and RSOM are now used in a range of preclinical and clinical studies, including advancing characterization of psoriasis, breast tumors, metastatic melanoma and inflammation in Crohn's disease. MSOT has also been used to visualize metabolism within brown fat, suggesting it may be effective for analyzing muscle energetics and lipid metabolism in a much simpler and more accessible way than with other techniques such as magnetic resonance imaging. Ntziachristos is a founder of iThera Medical GmbH, which currently commercializes optoacoustic technology and has placed systems around the world.Ntziachristos is author or co-author of more than 400 publications in peer reviewed journals and a holder of more than 25 patents. His work has been cited more than 33,000 times (as at October 2018). His h-index is 88.