Lithium hydride
Before the Castle Bravo nuclear weapons test in 1954, it was thought that only the less common isotope lithium-6 would breed tritium when struck with fast neutrons. The Castle Bravo test showed (accidentally) that the more plentiful lithium-7 also does so under extreme conditions, albeit by an endothermic reaction.
British hydrogen bomb programme
The successful test of an atomic bomb represented an extraordinary scientific and technological achievement. Britain became the world's third nuclear power, reaffirming its status as a great power, but hopes that the United States would be sufficiently impressed to restore the Special Relationship were soon dashed. On 1 November 1952, the United States conducted Ivy Mike, the first successful test of a true thermonuclear device (also known as a hydrogen bomb). Due to its physical size and use of cryogenic liquid deuterium, it was not suitable for use as a deliverable weapon, but the Castle Bravo test on 1 March 1954 used a much smaller device with solid lithium deuteride. Boosted by the nuclear fusion reaction in lithium-7, the yield of was more than twice what had been expected, and indeed was the largest detonation the Americans would ever carry out. This resulted in widespread radioactive fallout that affected 28 Americans, 236 Marshall Islanders, and the 23 crewmen of a Japanese fishing boat, the "Daigo Fukuryū Maru" ("Lucky Dragon No. 5"). Meanwhile, the Soviet Union tested Joe 4, a boosted fission weapon with a yield of on 12 August 1953. This was followed by Joe 19, a true two-stage thermonuclear weapon on 20 November 1954.