Strange quark
The first strange particle (a particle containing a strange quark) was discovered in 1947 (kaons), but the existence of the strange quark itself (and that of the up and down quarks) was only postulated in 1964 by Murray Gell-Mann and George Zweig to explain the Eightfold Way classification scheme of hadrons. The first evidence for the existence of quarks came in 1968, in deep inelastic scattering experiments at the Stanford Linear Accelerator Center. These experiments confirmed the existence of up and down quarks, and by extension, strange quarks, as they were required to explain the Eightfold Way.
Quark
In less than a year, extensions to the Gell-Mann–Zweig model were proposed. Sheldon Lee Glashow and James Bjorken predicted the existence of a fourth flavor of quark, which they called "charm". The addition was proposed because it allowed for a better description of the weak interaction (the mechanism that allows quarks to decay), equalized the number of known quarks with the number of known leptons, and implied a mass formula that correctly reproduced the masses of the known mesons.