Enrico Fermi
Fermi wrote a paper "On the Origin of Cosmic Radiation" in which he proposed that cosmic rays arose through material being accelerated by magnetic fields in interstellar space, which led to a difference of opinion with Teller. Fermi examined the issues surrounding magnetic fields in the arms of a spiral galaxy. He mused about what is now referred to as the "Fermi paradox": the contradiction between the presumed probability of the existence of extraterrestrial life and the fact that contact has not been made.
Toward the end of his life, Fermi questioned his faith in society at large to make wise choices about nuclear technology. He said:
Noogenesis
Therefore, generalizing and summarizing: 
The term "noogenesis" can be used in a variety of fields i.e. medicine, biophysics, semiotics, mathematics, information technology, psychology, theory of global evolution etc. thus making it a truly cross-disciplinary one. In astrobiology noogenesis concerns the origin of intelligent life and more specifically technological civilizations capable of communicating with humans and or traveling to Earth. The lack of evidence for the existence of such extraterrestrial life creates the Fermi paradox.