Nuclear triad
Israel is known to have nuclear-capable aircraft and land-base missiles, with the addition of nuclear-armed submarines this would mean that they now have a full triad of land-, air-, and sea-based nuclear delivery systems some of which would be invulnerable to a first strike by an enemy for the first time in their country's history. No other nation in the Middle East in known to be in possession of nuclear weapons, even though Iran, Iraq, Syria and Libya have started development programs that were never completed.
Nuclear-weapon-free zone
The UK, France, and the USA share a nuclear umbrella with the 25 other members of NATO, and the 6 European Union states not part of NATO (Austria, Cyprus, Ireland, Malta, Sweden, Finland) are part of the EU's Common Security and Defence Policy.