Cholera outbreaks and pandemics
That year, cholera was transmitted along the California, Mormon and Oregon Trails as 6,000 to 12,000 are believed to have died on their way to the California Gold Rush, Utah and Oregon in the cholera years of 1849–1855. It is believed more than 150,000 Americans died during the two pandemics between 1832 and 1849.
The Oregon Trail (1971 video game)
When hunting, or when attacked, the game prompts the player to type a word—"BANG" in the original version, or a randomly selected word like "BANG" or "POW" in later versions—with misspellings resulting in no effect. When hunting, the faster the word is typed, the more food is gathered. The game ends when the player reaches Oregon, or if they die along the trail; death can occur due to an attack or by running out of supplies. Running out of food results in starvation, while lack of clothing in cold weather, low levels of food, or random events such as snakebite or a hunting accident lead to illness; this results in death if the player does not have miscellaneous supplies for minor or regular illnesses, or cannot afford a doctor in the case of serious illnesses.