Raphael
By the end of 1508, Raphael had moved to Rome, where he lived for the rest of his life. He was invited by the new Pope Julius II, perhaps at the suggestion of his architect Donato Bramante, then engaged on St. Peter's Basilica, who came from just outside Urbino and was distantly related to Raphael. Unlike Michelangelo, who had been kept lingering in Rome for several months after his first summons, Raphael was immediately commissioned by Julius to fresco what was intended to become the Pope's private library at the Vatican Palace. This was a much larger and more important commission than any he had received before; he had only painted one altarpiece in Florence itself. Several other artists and their teams of assistants were already at work on different rooms, many painting over recently completed paintings commissioned by Julius's loathed predecessor, Alexander VI, whose contributions, and arms, Julius was determined to efface from the palace. Michelangelo, meanwhile, had been commissioned to paint the Sistine Chapel ceiling.
Raphaelle Peale
He married Martha (Patty) McGlathery at the age of twenty, and with her had eight children. For about two years beginning in 1803, Peale toured Virginia with the "physiognotrace", a profile making machine, with which he was briefly successful. By 1806 he had begun to suffer the symptoms of arsenic and mercury poisoning brought on by his work as a taxidermist in his father's museum. In August 1809 he was hospitalized with delirium, and for the rest of his life he suffered debilitating attacks almost yearly—which his father ascribed to "gout of the stomach" caused by consumption of pickles and excessive drinking. From 1810, Peale concentrated on still-life painting almost exclusively, becoming America's first professional still-life painter, and he exhibited frequently at the Pennsylvania Academy of the Fine Arts and elsewhere, especially from 1814–18. By 1813, he was unable to walk without crutches. After the downturn in his health, in an era when most artists considered still life a subject worthy only of amateurs, he devoted himself almost exclusively to still life painting. It is for these works he is best known. His work was on frequent exhibit at the Pennsylvania Academy of the Fine Arts between 1814 and 1818. After reportedly indulging in a night of heavy drinking, his health destroyed, he died on March 4, 1825, at age 51 at his home in Philadelphia.