Enrico Fermi
Fermi wrote a paper "On the Origin of Cosmic Radiation" in which he proposed that cosmic rays arose through material being accelerated by magnetic fields in interstellar space, which led to a difference of opinion with Teller. Fermi examined the issues surrounding magnetic fields in the arms of a spiral galaxy. He mused about what is now referred to as the "Fermi paradox": the contradiction between the presumed probability of the existence of extraterrestrial life and the fact that contact has not been made.
Toward the end of his life, Fermi questioned his faith in society at large to make wise choices about nuclear technology. He said:
Fermi paradox
This is the argument that technological civilizations may usually or invariably destroy themselves before or shortly after developing radio or spaceflight technology. Possible means of annihilation are many, including war, accidental environmental contamination or damage, resource depletion, climate change, or poorly designed artificial intelligence. This general theme is explored both in fiction and in scientific hypothesizing. In 1966, Sagan and Shklovskii speculated that technological civilizations will either tend to destroy themselves within a century of developing interstellar communicative capability or master their self-destructive tendencies and survive for billion-year timescales. Self-annihilation may also be viewed in terms of thermodynamics: insofar as life is an ordered system that can sustain itself against the tendency to disorder, the "external transmission" or interstellar communicative phase may be the point at which the system becomes unstable and self-destructs.