Strange quark
The first strange particle (a particle containing a strange quark) was discovered in 1947 (kaons), but the existence of the strange quark itself (and that of the up and down quarks) was only postulated in 1964 by Murray Gell-Mann and George Zweig to explain the Eightfold Way classification scheme of hadrons. The first evidence for the existence of quarks came in 1968, in deep inelastic scattering experiments at the Stanford Linear Accelerator Center. These experiments confirmed the existence of up and down quarks, and by extension, strange quarks, as they were required to explain the Eightfold Way.
Flavour (particle physics)
The terms "strange" and "strangeness" predate the discovery of the quark, but continued to be used after its discovery for the sake of continuity (i.e. the strangeness of each type of hadron remained the same); strangeness of anti-particles being referred to as +1, and particles as −1 as per the original definition. Strangeness was introduced to explain the rate of decay of newly discovered particles, such as the kaon, and was used in the Eightfold Way classification of hadrons and in subsequent quark models. These quantum numbers are preserved under strong and electromagnetic interactions, but not under weak interactions.