Endocrine gland
The adrenal glands are located above the kidneys in humans and in front of the kidneys in other animals. The adrenal glands produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol. It controls the behaviour during crisis and emotional situations. It stimulates the heart and its conducting tissues and metabolic processes.
Beta-3 adrenergic receptor
It is located mainly in adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Some β agonists have demonstrated antistress effects in animal studies, suggesting it also has a role in the central nervous system (CNS). β receptors are found in the gallbladder, urinary bladder, and in brown adipose tissue. Their role in gallbladder physiology is unknown, but they are thought to play a role in lipolysis and thermogenesis in brown fat. In the urinary bladder it is thought to cause relaxation of the bladder and prevention of urination.