History of quantum field theory
The third thread in the development of quantum field theory was the need to handle the statistics of many-particle systems consistently and with ease. In 1927, Pascual Jordan tried to extend the canonical quantization of fields to the many-body wave functions of identical particles using a formalism which is known as statistical transformation theory; this procedure is now sometimes called second quantization. In 1928, Jordan and Eugene Wigner found that the quantum field describing electrons, or other fermions, had to be expanded using anti-commuting creation and annihilation operators due to the Pauli exclusion principle (see Jordan–Wigner transformation). This thread of development was incorporated into many-body theory and strongly influenced condensed matter physics and nuclear physics.
Cosmological constant problem
After the development of quantum field theory in the 1940s, the first to address contributions of quantum fluctuations to the cosmological constant was Zel’dovich (1967, 1968). In quantum mechanics, the vacuum itself should experience quantum fluctuations. In general relativity, those quantum fluctuations constitute energy that would add to the cosmological constant. However, this calculated vacuum energy density is many orders of magnitude bigger than the observed cosmological constant. Original estimates of the degree of mismatch were as high as 120 orders of magnitude; however, modern research suggests that, when Lorentz invariance is taken into account, the degree of mismatch is closer to 60 orders of magnitude.