Nuclear triad
Israel is known to have nuclear-capable aircraft and land-base missiles, with the addition of nuclear-armed submarines this would mean that they now have a full triad of land-, air-, and sea-based nuclear delivery systems some of which would be invulnerable to a first strike by an enemy for the first time in their country's history. No other nation in the Middle East in known to be in possession of nuclear weapons, even though Iran, Iraq, Syria and Libya have started development programs that were never completed.
Nuclear weapon
Nuclear weapons have also been opposed by agreements between countries. Many nations have been declared Nuclear-Weapon-Free Zones, areas where nuclear weapons production and deployment are prohibited, through the use of treaties. The Treaty of Tlatelolco (1967) prohibited any production or deployment of nuclear weapons in Latin America and the Caribbean, and the Treaty of Pelindaba (1964) prohibits nuclear weapons in many African countries. As recently as 2006 a Central Asian Nuclear Weapon Free Zone was established among the former Soviet republics of Central Asia prohibiting nuclear weapons.