Hydroxide
Hydroxide is a diatomic anion with chemical formula OH. It consists of an oxygen and hydrogen atom held together by a covalent bond, and carries a negative electric charge. It is an important but usually minor constituent of water. It functions as a base, a ligand, a nucleophile, and a catalyst. The hydroxide ion forms salts, some of which dissociate in aqueous solution, liberating solvated hydroxide ions. Sodium hydroxide is a multi-million-ton per annum commodity chemical. A hydroxide attached to a strongly electropositive center may itself ionize, liberating a hydrogen cation (H), making the parent compound an acid.
Hydroxide
The hydroxide ion may act as a base catalyst. The base abstracts a proton from a weak acid to give an intermediate that goes on to react with another reagent. Common substrates for proton abstraction are alcohols, phenols, amines, and carbon acids. The p"K" value for dissociation of a C–H bond is extremely high, but the pK alpha hydrogens of a carbonyl compound are about 3 log units lower. Typical p"K" values are 16.7 for acetaldehyde and 19 for acetone. Dissociation can occur in the presence of a suitable base.
The base should have a p"K" value not less than about 4 log units smaller or the equilibrium will lie almost completely to the left.