Microglia
Research has discovered dystrophic (defective development) human microglia. "These cells are characterized by abnormalities in their cytoplasmic structure, such as deramified, atrophic, fragmented or unusually tortuous processes, frequently bearing spheroidal or bulbous swellings." The incidence of dystrophic microglia increases with aging. Microglial degeneration and death have been reported in research on Prion disease, Schizophrenia and Alzheimer's disease, indicating that microglial deterioration might be involved in neurodegenerative diseases. A complication of this theory is the fact that it is difficult to distinguish between "activated" and "dystrophic" microglia in the human brain.
Micrography
Micrography (from Greek, literally small-writing – "Μικρογραφία"), also called microcalligraphy, is a Jewish form of calligrams developed in the 9th century, with parallels in Christianity and Islam, utilizing minute Hebrew letters to form representational, geometric and abstract designs. Colored micrography is especially distinctive because these rare artworks are customarily rendered in black and white.