Nuclear triad
Israel is known to have nuclear-capable aircraft and land-base missiles, with the addition of nuclear-armed submarines this would mean that they now have a full triad of land-, air-, and sea-based nuclear delivery systems some of which would be invulnerable to a first strike by an enemy for the first time in their country's history. No other nation in the Middle East in known to be in possession of nuclear weapons, even though Iran, Iraq, Syria and Libya have started development programs that were never completed.
India and weapons of mass destruction
The Republic of India has developed and possesses weapons of mass destruction in the form of nuclear weapons. Though India has not made any official statements about the size of its nuclear arsenal, recent estimates suggest that India has 110 nuclear weapons — consistent with earlier estimates that it had produced enough weapons-grade plutonium for up to 75–110 nuclear weapons. In 1999, India was estimated to have 800 kg of separated reactor-grade plutonium, with a total amount of 8,300 kg of civilian plutonium, enough for approximately 1,000 nuclear weapons.