Nuclear triad
Israel is known to have nuclear-capable aircraft and land-base missiles, with the addition of nuclear-armed submarines this would mean that they now have a full triad of land-, air-, and sea-based nuclear delivery systems some of which would be invulnerable to a first strike by an enemy for the first time in their country's history. No other nation in the Middle East in known to be in possession of nuclear weapons, even though Iran, Iraq, Syria and Libya have started development programs that were never completed.
Nuclear famine
While the total number of global nuclear weapons had declined by two thirds following the U.S.-Soviet Strategic Arms Reduction Treaty (START) compared to the early 80s, some experts feel that the risk of nuclear conflict has not decreased, but has instead risen. This is due to nuclear proliferation as more countries such as India, Pakistan, and North Korea now have nuclear arsenals, increasing the risk of regional nuclear conflicts. Growing military tensions, accidents, sabotages and cyber-attacks are all potential trigger points of massive nuclear disruption and regional, if not global famine.