Phytophthora ramorum
Trials of silvicultural methods for treating "P. ramorum" began in Humboldt County in northwest coastal California in 2006. The trials have taken place on a variety of infested properties both private and public and have generally focused on varying levels and kinds of host removal. The largest () and most replicated trials have involved removal of tanoak and bay laurel by chainsaw throughout the infested stand, both with and without subsequent underburning designed to eliminate small seedlings and infested leaf litter. Other treatments included host removal in a modified “shaded fuelbreak” design in which all bay laurel is removed, but not all tanoaks; bay and tanoak removal using herbicides; and removal of bay laurel alone. The results of these treatments are still being monitored, but repeated sampling has so far detected only very small amounts of "P. ramorum" in the soil or on vegetation in the treated sites.
Podophyllotoxin
Podophyllotoxin (PPT), also known as podofilox, is a medical cream that is used to treat genital warts and molluscum contagiosum. It is not recommended in HPV infections without external warts. It can be applied either by a healthcare provider or the person themselves.
It is a non-alkaloid toxin lignan extracted from the roots and rhizomes of "Podophyllum" species. A less refined form known as podophyllum resin is also available, but has greater side effects.
Podophyllotoxin was isolated in 1880. In the United Kingdom the price for the NHS of 3.5 ml of medication is about 14.49 pounds. In the United States the price of a course of treatment is more than $200.