Lawrence, Kansas
Prior to Kansas Territory being established in May 1854, most of Douglas County was part of the Shawnee Indian Reservation (created in 1830). During this period, the Oregon Trail ran parallel to the Kansas River, roughly through the area where Lawrence would eventually be situated and a hill known then as "Hogback Ridge" (i.e., Mount Oread, which sits on the water divide separating the Kansas and Wakarusa River). This area was used as a landmark and an outlook by those on the trail. While this territory was technically unopened to settlement prior to 1854, there did exist a few "squatter settlements" in the area, especially just north of the Kansas River.
Kansas–Nebraska Act
The bill was reported to the main body of the Senate on January 4, 1854. It had been modified by Douglas, who had also authored the New Mexico Territory and Utah Territory Acts, to mirror the language from the Compromise of 1850. In the bill, a vast new Nebraska Territory was created to extend from Kansas north all the way to the 49th parallel, the US–Canada border. A large portion of Nebraska Territory would soon be split off into Dakota Territory (1861), and smaller portions transferred to Colorado Territory (1861) and Idaho Territory (1863) before the balance of the land became the State of Nebraska in 1867.