Enrico Fermi
Fermi wrote a paper "On the Origin of Cosmic Radiation" in which he proposed that cosmic rays arose through material being accelerated by magnetic fields in interstellar space, which led to a difference of opinion with Teller. Fermi examined the issues surrounding magnetic fields in the arms of a spiral galaxy. He mused about what is now referred to as the "Fermi paradox": the contradiction between the presumed probability of the existence of extraterrestrial life and the fact that contact has not been made.
Toward the end of his life, Fermi questioned his faith in society at large to make wise choices about nuclear technology. He said:
Accelerating change
Applying this vision to the search for extraterrestrial intelligence leads to the idea that advanced intelligent life reconfigures itself into a black hole. Such advanced life forms would be interested in inner space, rather than outer space and interstellar expansion. They would thus in some way transcend reality, not be observable and it would be a solution to Fermi's paradox called the "transcension hypothesis", Another solution is that the black holes we observe could actually be interpreted as intelligent super-civilizations feeding on stars, or "stellivores". 
This dynamics of evolution and development is an invitation to study the universe itself as evolving, developing. If the universe is a kind of superorganism, it may possibly tend to reproduce, naturally or artificially, with intelligent life playing a role.