2011 Tōhoku earthquake and tsunami
It was reported that radioactive iodine was detected in the tap water in Fukushima, Tochigi, Gunma, Tokyo, Chiba, Saitama, and Niigata, and radioactive caesium in the tap water in Fukushima, Tochigi and Gunma. Radioactive caesium, iodine, and strontium were also detected in the soil in some places in Fukushima. There may be a need to replace the contaminated soil. Many radioactive hotspots were found outside the evacuation zone, including Tokyo. Food products were also found contaminated by radioactive matter in several places in Japan. On 5 April 2011, the government of the Ibaraki Prefecture banned the fishing of sand lance after discovering that this species was contaminated by radioactive caesium above legal limits. As late as July 2013 slightly elevated levels of radioactivity were found in beef on sale at Tokyo markets.
Nuclear fission product
The administration of known goitrogen substances can also be used as a prophylaxis in reducing the bio-uptake of iodine, (whether it be the nutritional non-radioactive iodine-127 or radioactive iodine, radioiodine - most commonly iodine-131, as the body cannot discern between different iodine isotopes).
Perchlorate ions, a common water contaminant in the USA due to the aerospace industry, has been shown to reduce iodine uptake and thus is classified as a goitrogen. Perchlorate ions are a competitive inhibitor of the process by which iodide is actively deposited into thyroid follicular cells. Studies involving healthy adult volunteers determined that at levels above 0.007 milligrams per kilogram per day (mg/(kg·d)), perchlorate begins to temporarily inhibit the thyroid gland’s ability to absorb iodine from the bloodstream ("iodide uptake inhibition", thus perchlorate is a known goitrogen).
The reduction of the iodide pool by perchlorate has dual effects – reduction of excess hormone synthesis and hyperthyroidism, on the one hand, and reduction of thyroid inhibitor synthesis and hypothyroidism on the other. Perchlorate remains very useful as a single dose application in tests measuring the discharge of radioiodide accumulated in the thyroid as a result of many different disruptions in the further metabolism of iodide in the thyroid gland.