Mickey Mouse universe
In "Plane Crazy" (1929), the first produced Mickey Mouse story, Mickey is seen at a farm. In all of his early films Mickey is in a rural setting, but most commonly at a farm. This setting was succinctly presented in the first sentences of one of Mickey's first storybooks:
Live-action animated film
During the popularity of the silent film in 1920s and 1930s, the popular animated cartoons of Max Fleischer included a series where his cartoon character Koko the Clown interacted with the live world; for example, having a boxing match with a live kitten. In a variation from this and inspired by Fleischer, Walt Disney's first directorial efforts, years before Oswald the Lucky Rabbit was born in 1927 and Mickey Mouse in 1928, were the live-action animated "Alice Comedies" cartoons, in which a young live-action girl named Alice interacted with animated cartoon characters.