Cholera outbreaks and pandemics
That year, cholera was transmitted along the California, Mormon and Oregon Trails as 6,000 to 12,000 are believed to have died on their way to the California Gold Rush, Utah and Oregon in the cholera years of 1849–1855. It is believed more than 150,000 Americans died during the two pandemics between 1832 and 1849.
The Oregon Trail (1971 video game)
The game is the first entry in "The Oregon Trail" series; games in the series have since been released in many editions by various developers and publishers, many titled "The Oregon Trail". The multiple games in the series are often considered to be iterations on the same title, and have collectively sold over 65 million copies and have been inducted into the World Video Game Hall of Fame. The series has also inspired a number of spinoffs such as "The Yukon Trail" and "The Amazon Trail".