Cholera outbreaks and pandemics
That year, cholera was transmitted along the California, Mormon and Oregon Trails as 6,000 to 12,000 are believed to have died on their way to the California Gold Rush, Utah and Oregon in the cholera years of 1849–1855. It is believed more than 150,000 Americans died during the two pandemics between 1832 and 1849.
Oregon Desert Trail
The Oregon Desert Trail was envisioned by the nonprofit organization, Oregon Natural Desert Association (ONDA), as a way for people to connect to the landscape. 
The first thru-hike was made in the summer of 2013 by 33-year-old Bend resident Sage Clegg and took just under six weeks. During her hike Clegg reported trail conditions to ONDA, and gathered information to help make the route traversable for other trail users.