Dolly (sheep)
Dolly was born on 5 July 1996 and had three mothers: one provided the egg, another the DNA, and a third carried the cloned embryo to term. She was created using the technique of somatic cell nuclear transfer, where the cell nucleus from an adult cell is transferred into an unfertilized oocyte (developing egg cell) that has had its cell nucleus removed. The hybrid cell is then stimulated to divide by an electric shock, and when it develops into a blastocyst it is implanted in a surrogate mother. Dolly was the first clone produced from a cell taken from an adult mammal. The production of Dolly showed that genes in the nucleus of such a mature differentiated somatic cell are still capable of reverting to an embryonic totipotent state, creating a cell that can then go on to develop into any part of an animal. Dolly's existence was announced to the public on 22 February 1997. It gained much attention in the media. A commercial with Scottish scientists playing with sheep was aired on TV, and a special report in "Time" magazine featured Dolly the sheep. "Science" featured Dolly as the breakthrough of the year. Even though Dolly was not the first animal cloned, she received media attention because she was the first cloned from an adult cell.
Patty Duke
Anna Marie "Patty" Duke (December 14, 1946 – March 29, 2016) was an American actress, appearing on stage, film, and television. Her first big break came from her Academy Award winning performance at age 16 for portraying Helen Keller in "The Miracle Worker" (1962), a role that she had originated on Broadway. The following year she was given her own show, "The Patty Duke Show," in which she played "identical cousins" Cathy and Patty Lane. She later progressed to more mature roles such as that of Neely O'Hara in the film "Valley of the Dolls" (1967). Over the course of her career, she received ten Emmy Award nominations and three Emmy Awards, and two Golden Globe Awards. Duke also served as president of the Screen Actors Guild from 1985 to 1988.