Enrico Fermi
Fermi wrote a paper "On the Origin of Cosmic Radiation" in which he proposed that cosmic rays arose through material being accelerated by magnetic fields in interstellar space, which led to a difference of opinion with Teller. Fermi examined the issues surrounding magnetic fields in the arms of a spiral galaxy. He mused about what is now referred to as the "Fermi paradox": the contradiction between the presumed probability of the existence of extraterrestrial life and the fact that contact has not been made.
Toward the end of his life, Fermi questioned his faith in society at large to make wise choices about nuclear technology. He said:
Great Filter
There are many alternative scenarios that might allow for the evolution of intelligent life to occur multiple times without either catastrophic self-destruction or glaringly visible evidence. These are possible resolutions to the Fermi paradox: "They do exist, but we see no evidence". Other ideas include: it is too expensive to spread physically throughout the galaxy, Earth is purposely isolated, it is dangerous to communicate and hence civilizations actively hide, among others.