U.S. Route 20
U.S. Highway 20 (US 20) is an east–west United States highway that stretches from the Pacific Northwest all the way to New England. The "0" in its route number indicates that US 20 is a coast-to-coast route. Spanning , it is the longest road in the United States, and particularly from Newport, Oregon to Boston, Massachusetts, the route is roughly parallel to that of the newer Interstate 90 (I-90), which is in turn the longest Interstate Highway in the U.S. There is a discontinuity in the official designation of US 20 through Yellowstone National Park, with unnumbered roads used to traverse the park.
U.S. Route 64
Overall, US 64 runs from the Western edge of the state to the Outer Banks. It is the longest highway in North Carolina. In North Carolina, the common way to express coverage of the entire state is to say, "from Manteo to Murphy." US 64 runs through both.