History of animal testing
In 1996 Dolly the sheep was born, the first mammal to be cloned from an adult cell. The process by which Dolly the sheep was cloned utilized a process known as nuclear transfer applied by lead scientist Ian Wilmut. Although other scientists were not immediately able to replicate the experiment, Wilmut argued that the experiment was indeed repeatable, given a timeframe of over a year.
Dolly Dimples (comic strip)
King Features' archivist dates the character's debut as March 22, 1903, although at that point she was called Toodles, as part of the strip "Naughty Toodles", which ran from 1903 to 1904. An analog character appeared in two non-Hearst strips, "The Adventures of Dolly Drake and Bobby Blake in Storyland" (Philadelphia Press, 1905–1906) and "The Turr’ble Tales of Kaptain Kiddo" (1909), both written by Drayton's sister Margaret G. Hays.