Nuclear triad
Israel is known to have nuclear-capable aircraft and land-base missiles, with the addition of nuclear-armed submarines this would mean that they now have a full triad of land-, air-, and sea-based nuclear delivery systems some of which would be invulnerable to a first strike by an enemy for the first time in their country's history. No other nation in the Middle East in known to be in possession of nuclear weapons, even though Iran, Iraq, Syria and Libya have started development programs that were never completed.
Nuclear power
As of April 2012 there were thirty one countries that have civil nuclear power plants, of which nine have nuclear weapons, with the vast majority of these nuclear weapons states having first produced weapons, before commercial fission electricity stations.
Moreover, the re-purposing of civilian nuclear industries for military purposes would be a breach of the Non-proliferation treaty, of which 190 countries adhere to.