Nuclear triad
Israel is known to have nuclear-capable aircraft and land-base missiles, with the addition of nuclear-armed submarines this would mean that they now have a full triad of land-, air-, and sea-based nuclear delivery systems some of which would be invulnerable to a first strike by an enemy for the first time in their country's history. No other nation in the Middle East in known to be in possession of nuclear weapons, even though Iran, Iraq, Syria and Libya have started development programs that were never completed.
Nuclear weapon
In 2013, Mark Diesendorf said that governments of France, India, North Korea, Pakistan, UK, and South Africa have used nuclear power and/or research reactors to assist nuclear weapons development or to contribute to their supplies of nuclear explosives from military reactors.