Dolly (sheep)
Dolly was born on 5 July 1996 and had three mothers: one provided the egg, another the DNA, and a third carried the cloned embryo to term. She was created using the technique of somatic cell nuclear transfer, where the cell nucleus from an adult cell is transferred into an unfertilized oocyte (developing egg cell) that has had its cell nucleus removed. The hybrid cell is then stimulated to divide by an electric shock, and when it develops into a blastocyst it is implanted in a surrogate mother. Dolly was the first clone produced from a cell taken from an adult mammal. The production of Dolly showed that genes in the nucleus of such a mature differentiated somatic cell are still capable of reverting to an embryonic totipotent state, creating a cell that can then go on to develop into any part of an animal. Dolly's existence was announced to the public on 22 February 1997. It gained much attention in the media. A commercial with Scottish scientists playing with sheep was aired on TV, and a special report in "Time" magazine featured Dolly the sheep. "Science" featured Dolly as the breakthrough of the year. Even though Dolly was not the first animal cloned, she received media attention because she was the first cloned from an adult cell.
Delightful Dolly
Delightful Dolly is a 1910 American silent short comedy produced by the Thanhouser Company. The film follows Marie Allen, an orphan girl who lives with her grandfather, who sees a large doll in the window of the shop. At night, she sneaks out to visit the shop with the doll, but finds it gone. She sneaks into the shop and ends up hiding in the box, to prevent from being discovered by the store clerk. She is taken to the home of the rich little girl, Daisy. After taking the doll's clothes, Marie hides in the box as Daisy approaches. When Daisy opens the box, Marie acts like a doll. When Daisy takes a break for food, Marie secretly takes the food and drink much to Daisy's bewilderment. Marie's grandfather arrives at the home and explains the situation and Marie receives the doll from the family. Little is known about the production or cast of the film, but Marie Eline played the role of Marie. The film was released on October 14, 1910 and was met with some praise in trade publications. The film is presumed lost.