Radioactive contamination
Some organs concentrate certain elements and hence radionuclide variants of those elements. This action may lead to much lower removal rates. For instance, the thyroid gland takes up a large percentage of any iodine that enters the body. Large quantities of inhaled or ingested radioactive iodine may impair or destroy the thyroid, while other tissues are affected to a lesser extent. Radioactive iodine-131 is a common fission product; it was a major component of the radioactivity released from the Chernobyl disaster, leading to nine fatal cases of pediatric thyroid cancer and hypothyroidism. On the other hand, radioactive iodine is used in the diagnosis and treatment of many diseases of the thyroid precisely because of the thyroid's selective uptake of iodine.
Committed dose
The intake of radioactive material can occur through four pathways:Some artificial radioisotopes such as iodine-131 are chemically identical to natural isotopes needed by the body, and may be more readily absorbed if the individual has a deficit of that element. For instance, Potassium iodide (KI), administered orally immediately after exposure, may be used to protect the thyroid from ingested radioactive iodine in the event of an accident or attack at a nuclear power plant, or the detonation of a nuclear explosive which would release radioactive iodine.