Quark
The quark model was independently proposed by physicists Murray Gell-Mann and George Zweig in 1964. Quarks were introduced as parts of an ordering scheme for hadrons, and there was little evidence for their physical existence until deep inelastic scattering experiments at the Stanford Linear Accelerator Center in 1968. Accelerator experiments have provided evidence for all six flavors. The top quark, first observed at Fermilab in 1995, was the last to be discovered.
Quark (Star Trek)
When the Bajoran wormhole was discovered, Quark helped broker deals between several Gamma Quadrant races and the Ferengi. The Alpha Quadrant's first knowledge of the Dominion came through business dealings that Quark and the Ferengi had in the Gamma Quadrant with the Karemma of the Dominion. Quark's role in these dealings came about as a result of the interference of Grand Nagus Zek. Quark became Grand Nagus for a brief period when it appeared that Zek had died; however, Zek's death turned out to be a ruse and Quark was promptly deposed. Along with Commander Sisko, Quark was also among the first to encounter the genetically engineered soldiers of the Dominion, the Jem'Hadar.