Estradiol valerate
In addition to single-drug formulations, oral estradiol valerate is available in combination with the progestin dienogest as a combined oral contraceptive and intramuscular estradiol valerate is marketed in combination with the progestins hydroxyprogesterone caproate and norethisterone enantate as combined injectable contraceptives. Intramuscular estradiol valerate has also been marketed in combination with testosterone enantate, but this formulation has been discontinued. The availability of estradiol valerate-containing products varies throughout the world.
Estriol (medication)
Estetrol (E4), also known as 15α-hydroxyestriol, is a naturally occurring analogue of estriol with an additional hydroxyl group, at the C15α position. It is closely related to estriol and has similar but non-identical pharmacological properties. Like estriol, estetrol is a relatively weak and atypical estrogen. Estetrol is under development for potential clinical use for a variety of indications, such as menopausal hormone therapy and hormonal birth control.https://adisinsight.springer.com/drugs/800034634