Lithium hydride
Before the Castle Bravo nuclear weapons test in 1954, it was thought that only the less common isotope lithium-6 would breed tritium when struck with fast neutrons. The Castle Bravo test showed (accidentally) that the more plentiful lithium-7 also does so under extreme conditions, albeit by an endothermic reaction.
Downwinders
One of these many tests, the March 1, 1954, explosion of Castle Bravo, a U.S. thermonuclear device, was responsible for most of the radiation the Marshall Islanders were exposed to. The fallout-related doses of this single test are believed to be the highest recorded in the history of worldwide nuclear testing. Many of the Marshall Islands which were part of the Pacific Proving Grounds remain contaminated by nuclear fallout, and many of those downwinders who were living on the islands at the time of testing have suffered from a highly increased incidence of several types of cancers and birth defects.