Quark
The quark model was independently proposed by physicists Murray Gell-Mann and George Zweig in 1964. Quarks were introduced as parts of an ordering scheme for hadrons, and there was little evidence for their physical existence until deep inelastic scattering experiments at the Stanford Linear Accelerator Center in 1968. Accelerator experiments have provided evidence for all six flavors. The top quark, first observed at Fermilab in 1995, was the last to be discovered.
Exotic hadron
When the quark model was first postulated by Murray Gell-Mann and others in the 1960s, it was to organize the states known then to be in existence in a meaningful way. As quantum chromodynamics (QCD) developed over the next decade, it became apparent that there was no reason why only three-quark and quark-antiquark combinations could exist. Indeed, Gell-Mann's original 1964 paper alludes to the possibility of exotic hadrons and classifies hadrons into baryons and mesons depending upon whether they have an odd (baryon) or even (meson) number of valence quarks. In addition, it seemed that gluons, the mediator particles of the strong interaction, could also form bound states by themselves (glueballs) and with quarks (hybrid hadrons). Several decades have passed without conclusive evidence of an exotic hadron that could be associated with the S-matrix pole.