Unethical human experimentation in the United States
In 1953, the AEC ran several studies at the University of Iowa on the health effects of radioactive iodine in newborns and pregnant women. In one study, researchers gave pregnant women from of iodine-131, in order to study the women's aborted embryos in an attempt to discover at what stage, and to what extent, radioactive iodine crosses the placental barrier. In another study, they gave 25 newborn babies (who were under 36 hours old and weighed from ) iodine-131, either by oral administration or through an injection, so that they could measure the amount of iodine in their thyroid glands, as iodine would go to that gland.
Iodane
Iodane generally refers to any organic derivative of iodine. Without modifier, "iodane" is the systematic name for the parent hydride of iodine, HI. Thus, any organoiodine compound with general formula RI (e.g., CHI or CHI) is a substituted iodane. However, as used in the context of organic synthesis, the term "iodane" more specifically refers to organoiodine compounds with nonstandard bond number (i.e., bond number greater than one), making this term a synonym for hypervalent iodine. These iodine compounds are hypervalent because the iodine atom formally contains more than the 8 electrons in the valence shell required for the octet rule. When iodine is ligated to an organic residue and electronegative ligands (e.g. halides or carboxylates), hypervalent iodine compounds occur with a +3 oxidation number as iodine(III) or λ-iodanes or as a +5 oxidation number as iodine(V) or λ-iodanes. (Here, lambda convention is used to give the nonstandard bond number.)