Endocrine gland
The adrenal glands are located above the kidneys in humans and in front of the kidneys in other animals. The adrenal glands produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol. It controls the behaviour during crisis and emotional situations. It stimulates the heart and its conducting tissues and metabolic processes.
Discovery and development of angiotensin receptor blockers
AT receptors are mainly found in the heart, adrenal glands, brain, liver and kidneys. Their main role is to regulate blood pressure as well as fluid and electrolyte balance. 
AT receptors are highly expressed in the developing fetus but they decline rapidly after birth. In the adult, AT receptors are present only at low levels and are mostly found in the heart, adrenal glands, uterus, ovaries, kidneys and brain.