Castle Bravo
Castle Bravo was the first in a series of high-yield thermonuclear weapon design tests conducted by the United States at Bikini Atoll, Marshall Islands, as part of "Operation Castle". Detonated on March 1, 1954, the device was the most powerful nuclear device detonated by the United States and its first lithium deuteride fueled thermonuclear weapon. Castle Bravo's yield was 15 megatons of TNT, 2.5 times the predicted 6.0 megatons, due to unforeseen additional reactions involving Li, which led to the unexpected radioactive contamination of areas to the east of Bikini Atoll.
Duck and cover
A notable comparison to underline this is found when one compares the 50 megaton air-burst Tsar Bomba, which produced no concentrated local/early fallout, and thus no known deaths from radiation, with the surface burst of the 15 megaton Castle Bravo, which in comparison, due to the local fallout produced, was implicated in the death of 1 of 23 crew on the Lucky Dragon and made the entire Bikini Atoll unfit for further nuclear testing until enough time elapsed and the intensity of the radiation field had decayed to acceptable levels.
Furthermore, regardless of if a nuclear attack on a city is of the surface or air-burst variety or a mixture of both, the advice to shelter in place, in the interior of well-built homes, or if available, fallout shelters, as suggested in the film "Duck and Cover", will drastically reduce one's chance of absorbing a hazardous dose of radiation. A real-world example of this occurred after the Castle Bravo test where, in contrast to the crew of the Lucky Dragon, the firing crew that triggered the explosion safely sheltered in their firing station until after a number of hours had passed and the radiation levels outside fell to dose rate levels safe enough for an evacuation to be considered. The comparative safety experienced by the Castle Bravo firing crew served as a proof of concept to civil defense personnel that shelter in place (or "buttoning up" as it was known then) is an effective strategy in mitigating the potentially serious health effects of local fallout.