Estradiol valerate
In addition to single-drug formulations, oral estradiol valerate is available in combination with the progestin dienogest as a combined oral contraceptive and intramuscular estradiol valerate is marketed in combination with the progestins hydroxyprogesterone caproate and norethisterone enantate as combined injectable contraceptives. Intramuscular estradiol valerate has also been marketed in combination with testosterone enantate, but this formulation has been discontinued. The availability of estradiol valerate-containing products varies throughout the world.
Estradiol monopropionate
Estradiol monopropionate (brand names Acrofollin, Agofollin, Akrofollin, Di-Ovahormon Depot, Follhormon, Ovocylin), also known as estradiol 17β-propionate or estradiol 17β-propanoate, as well as estra-1,3,5(10)-trien-3,17β-diol 17β-propionate, is a synthetic, steroidal estrogen and an estrogen ester – specifically, the C17β propionate ester of estradiol – which was first marketed in the late 1930s or early 1940s.