Nicholas II of Russia
On 1 March 1881, following the assassination of his grandfather, Tsar Alexander II, Nicholas became heir apparent upon his father's ascension as Alexander III. Nicholas and his other family members bore witness to Alexander II's death, having been present at the Winter Palace in Saint Petersburg, where he was brought after the attack. For security reasons, the new tsar and his family relocated their primary residence to the Gatchina Palace outside the city, only entering the capital for various ceremonial functions. On such occasions, Alexander III and his family occupied the nearby Anichkov Palace.
Death of Alexander the Great
Proposed causes of Alexander's death included alcoholic liver disease, fever, and strychnine poisoning, but little data support those versions. According to the University of Maryland School of Medicine report of 1998, Alexander probably died of typhoid fever (which, along with malaria, was common in ancient Babylon). In the week before Alexander's death, historical accounts mention chills, sweats, exhaustion and high fever, typical symptoms of infectious diseases, including typhoid fever. According to David W. Oldach from the University of Maryland Medical Center, Alexander also had "severe abdominal pain, causing him to cry out in agony". The associated account, however, comes from the unreliable "Alexander romance". According to Andrew N. Williams and Robert Arnott, in Alexander the Great's last days he became mute. He became mute because of a previous injury to his neck from the Siege of Cyropolis.