Interstate 80
I-80 is the Interstate Highway that most closely approximates the route of the historic Lincoln Highway, the first road across the United States. The highway roughly traces other historically significant travel routes in the Western United States: the Oregon Trail across Wyoming and Nebraska, the California Trail across most of Nevada and California, the first transcontinental airmail route, and except in the Great Salt Lake area, the entire route of the First Transcontinental Railroad. From near Chicago east to near Youngstown, Ohio, I-80 is a toll road, containing the majority of both the Indiana Toll Road and the Ohio Turnpike. I-80 runs concurrently with I-90 from near Portage, Indiana, to Elyria, Ohio. In Pennsylvania, I-80 is known as the Keystone Shortway, a non-tolled freeway that crosses rural north-central portions of the state on the way to New Jersey and New York City.
U.S. Route 53
U.S. Route 53, or U.S. Highway 53 (U.S. 53), is a north–south U.S. highway that runs for 403 miles (649 km) from La Crosse, Wisconsin to International Falls, Minnesota. It is the primary north–south route in northwestern Wisconsin, serving as a vital link between I-94 at Eau Claire, Wisconsin and the city of Duluth, Minnesota. The entire route from Eau Claire to the city limits of Superior, Wisconsin is a four lane divided highway. The highway's northern terminus is at the Fort Frances-International Falls Bridge in International Falls, Minnesota, at the Canada–US border. Its southern terminus is in La Crosse, Wisconsin, at U.S. Highway 14.