Atolla jellyfish
The body of "Atolla wyvillei" is a bell shape and it has several moderately long tentacles along the bell. The bell is around 20–174 mm in diameter. It also has a single long tentacle called a hypertrophied tentacle. This hypertrophied tentacle has several purposes, including aid in predation and aid in reproduction. These jellyfish do not have a digestive system, a respiratory system, a circulatory system or a central nervous system. Not having a central nervous system means that it lacks a brain.
Pain in fish
Microarray analysis of gene expression shows the brain is active at the molecular level in the forebrain, midbrain and hindbrain of common carp and rainbow trout. Several genes involved in mammalian nociception, such as brain-derived neurotrophic factor (BDNF) and the cannabinoid CB1 receptor are regulated in the fish brain after a nociceptive event.