Nuclear reactor physics
Modern deposits of uranium contain only up to ~0.7% U (and ~99.3% U), which is not enough to sustain a chain reaction moderated by ordinary water. But U has a much shorter half-life (700 million years) than U (4.5 billion years), so in the distant past the percentage of U was much higher. About two billion years ago, a water-saturated uranium deposit (in what is now the Oklo mine in Gabon, West Africa) underwent a naturally occurring chain reaction that was moderated by groundwater and, presumably, controlled by the negative void coefficient as the water boiled from the heat of the reaction. Uranium from the Oklo mine is about 50% depleted compared to other locations: it is only about 0.3% to 0.7% U; and the ore contains traces of stable daughters of long-decayed fission products.Fermi age theory
Uranium tile
Not long after Henri Becquerel discovered radioactivity in uranium salts, Madame Curie discovered both polonium and radium as two new radioactive elements also present with uranium.
The relatively high specific activity and moderate half-life of 1,600 years of Ra-226, the main radioisotope of radium found in uranium ore, made for a material which when mixed with a phosphor allowed for a glow-in-the-dark substance.