KHII-TV
On March 7, 2006, Raycom Media announced that KFVE would affiliate with MyNetworkTV as part of a group deal involving many of Raycom-owned affiliates of The WB and UPN (whose consolidation and shutdowns the following September resulted in the creation of The CW Television Network, which would affiliate in Hawaii with a digital subchannel of KHON-TV). KFVE officially joined MyNetworkTV on September 5, 2006 and did not air The WB's final two weeks of prime-time programming (though it continued to air WB daytime and Saturday morning programming until the end of the network's existence).
KIAH
On January 24, 2006, UPN parent company CBS Corporation (which split from Viacom in December 2005) and WB network parent Time Warner (through its Warner Bros. Entertainment division) announced that they would dissolve the two networks to create The CW, a joint network venture that initially featured a mix of original first-run series and programs that originated on The WB and UPN. The network signed a ten-year affiliation agreement with Tribune Broadcasting for 16 of the 19 WB affiliates that the company owned at the time, including KIAH, to serve as charter outlets of the network.
Nearly one month after the CW launch announcement, on February 22, 2006, News Corporation subsidiaries Fox Television Stations and Twentieth Television announced the launch of MyNetworkTV, a network created primarily to serve as a network programming option for UPN and WB stations that were left out of The CW's affiliation deals. That service committed all nine UPN-affiliated stations that corporate sister Fox Television Stations owned at the time, including KTXH, to serve as MyNetworkTV's charter affiliates. A few months later, the Federal Communications Commission approved a callsign change from KHWB to KHCW (standing for "Houston's CW"), which became official on April 27, 2006. On September 13, 2006, KHCW changed its on-air branding from "Houston's WB" to "CW 39", restoring the channel number to its branding. KHCW remained a WB affiliate until the network ceased operations on September 17, 2006; the station affiliated with The CW upon that network's debut on September 18. (KTXH joined MyNetworkTV upon that network's launch on September 5.)