2008 Orange Bowl
In the wake of the Hokies's defeat, Virginia Tech chose to start a new quarterback and a new offensive plan. Behind freshman Tyrod Taylor, the Hokies rolled to five straight victories, including a win over No. 22 Clemson by 18 points. During the winning streak, Sean Glennon, who had started at quarterback for the Hokies during the first two games of the season, returned to alternate possessions with Taylor in an unusual two-quarterback system. On October 25, the Hokies had a chance to make up for their early-season loss to LSU when they faced No. 2 Boston College on a Thursday night in Blacksburg, Virginia. Though the Hokies dominated for most of the game, Boston College quarterback Matt Ryan managed a late-game comeback to win the game 14–10 with 11 seconds remaining.
2006–07 NCAA football bowl games
The third BCS game, the FedEx Orange Bowl, was played at Dolphin Stadium in Miami Gardens, Florida on January 2, 2007. The Big East Conference champions, the University of Louisville Cardinals, beat the Wake Forest University Demon Deacons, winners of the ACC, 24–13. Louisville entered the game as heavy favorites, but their offense sputtered early and the game was tied 10–10 at halftime. Wake Forest took a 13–10 lead in the fourth quarter but Louisville scored two unanswered touchdowns on drives of 81 and 72 yards to take an 11-point lead, after which Wake Forest was unable to score. Brian Brohm completed 24 of 34 passes and was named the game's MVP. Brohm's 311 passing yards were the third most in Orange Bowl history, behind only Tom Brady (in 2000 for Michigan against Alabama) and Matt Leinart (in 2005 for Southern California against Oklahoma). In addition, the Cardinals' win clinched the ESPN-sponsored Bowl Challenge Cup as the much-maligned Big East, who were in their second year of their new football alignment, had a 4–0 record with one game remaining passing the Mountain West and Western Athletic Conferences, who had 3–1 records and completed their games.