Orientia tsutsugamushi
"O. tsutsugamushi" causes a complex and dangerous infection scrub typhus. Infection starts when chiggers bite on the skin during their feeding. The bacteria are deposited at the site of feeding (inoculation), where they multiply. They cause progressive tissue damage (necrosis). Necrosis progresses to inflammation of the blood vessels called vasculitis. This in turn causes inflammation of the lymph nodes, called lymphadenopathy. Within a few days, vasculitis extends to various organs including liver, brain, kidney, meninges and the lung. The disease is responsible for nearly a quarter of all the febrile (high fever) illness in endemic areas. Mortality in severe case or due to improper treatment or misdiagnosis may be as high as 30-70%. About 6% of infected people die untreated, and 1.4% of the patients die even with medical treatment. Moreover, death rate can be as high as 13% where medical treatment is not properly handled. In cases of misdiagnosis and failure of treatment, systemic complications rapidly develop including acute respiratory distress syndrome, acute kidney failure, encephalitis, gastrointestinal bleeding, hepatitis, meningitis, myocarditis, pancreatitis, pneumonia, septic shock, sub-acute thyroiditis, and multi-organ dysfunctions. Harmful symptoms involving multiple organ failure and neurological impairment are difficult to treat, and can be lifelong debilitation or directly fatal. The central nervous system is often affected and result in various complications including cerebellitis, cranial nerve palsies, meningoencephalitis, plexopathy, transverse myelitis, neuroleptic malignant syndrome, and Guillan-Barré syndrome. Death rates due to complications can be up to 14% in brain infections, and 24% with multiple organ failure. It is the major cause of acute encephalitis syndrome in India, where viral infection Japanese encephalitis has been regarded as the main factor.
Last Rites of the Dead
The Commandant, who appears to be suffering from a nervous breakdown, disguises herself by chopping off her hair and dying it blonde. She shoots herself in the head, turning herself into one of the undead and poses as a victim of her own anti-zombie group. She is eventually taken into Solstice's compound where she wreaks havoc. Josh follows her there, and sets off to kill Angela. As the Commandant fights her way through Solstice's zombie army, and Josh struggles to fight his way into the compound, Angela escapes from her bonds and battles with the Good Mother Solstice eventually injecting her with a full dose of her liquid flesh concoction, causing an overdose with messy results. Commandant ultimately kills most of Solstice's army, but not before being disemboweled and left partially paralyzed. Josh and Angela battle, and Angela blows Josh's leg off with a shotgun and castrates him. Angela leaves, with Josh still professing his love for her. The Commandant turns up and blows Josh's head off with her shotgun, and then turns the gun on herself.