Giant hutia
The giant hutias are an extinct group of large rodents known from fossil and subfossil material in the West Indies. One species, "Amblyrhiza inundata", is estimated to have weighed between , big specimens being as large as an American black bear. This is twice as large as the capybara, the largest rodent living today, but still much smaller than "Josephoartigasia monesi", the largest rodent known. These animals were probably used as a food source by aboriginal humans. All giant hutias are in a single family, Heptaxodontidae, which contains no living species; this grouping seems to be paraphyletic and artificial, however.
Muskrat
The muskrat is the largest species in the subfamily Arvicolinae, which includes 142 other species of rodents, mostly voles and lemmings. Muskrats are referred to as "rats" in a general sense because they are medium-sized rodents with an adaptable lifestyle and an omnivorous diet. They are not, however, members of the genus "Rattus".