Vorinostat
A recent study suggested that vorinostat also possesses some activity against recurrent glioblastoma multiforme, resulting in a median overall survival of 5.7 months (compared to 4–4.4 months in earlier studies). Further brain tumor trials are planned in which vorinostat will be combined with other drugs.
John McCain
McCain underwent a minimally invasive craniotomy at Mayo Clinic Hospital in Phoenix, Arizona, on July 14, 2017, in order to remove a blood clot above his left eye. His absence prompted Senate Majority Leader Mitch McConnell to delay a vote on the Better Care Reconciliation Act. Five days later, Mayo Clinic doctors announced that the laboratory results from the surgery confirmed the presence of a glioblastoma, which is a very aggressive brain tumor. Standard treatment options for this tumor include chemotherapy and radiation, although even with treatment, average survival time is approximately 14 months. McCain was a survivor of previous cancers, including melanoma.