Prewrath
According to prewrath, this passage clearly indicates that the coming of the Lord and the Day of the Lord are part and parcel of the same event, the coming of the Lord. First, Jesus arrives in the sky at His Second Coming, at which time He raptures all Christian believers, then His judgment during the Day of the Lord falls upon those who have disbelieved and rejected His lordship.
This is justified, according to prewrath, by the fact that Jesus places His return (Matthew 24:30–31) after the abomination of desolation (Matthew 24:15), which occurs at the midpoint of the 70th Week (cf. Daniel 9:27, Daniel 11:31). Thus, if the Second Coming and rapture occur after the sixth seal, this places this event after the midpoint but before the end (seventh trumpet).
Antichrist
Origen (185–254) refuted Celsus's view of the Antichrist. Origen utilized Scriptural citations from Daniel, Paul, and the Gospels. He argued:
Cyril of Jerusalem, in the mid-4th century, delivered his 15th Catechetical lecture about the Second Coming of Jesus Christ, in which he also lectures about the Antichrist, who will reign as the ruler of the world for three and a half years, before he is killed by Jesus Christ right at the end of his three-and-a-half-year reign, shortly after which the Second Coming of Jesus Christ will happen.