Big Apple
Although the history of "Big Apple " was once thought a mystery, a clearer picture of the term's history has emerged due to the work of amateur etymologist Barry Popik, and Gerald Cohen of Missouri University of Science and Technology. A number of false theories had previously existed, including a claim that the term derived from a woman named Eve who ran a brothel in the city. This was subsequently exposed as a hoax.
List of cities nicknamed by Americans after fruits
Ostensibly, the first was Big Apple, from which the others have been deemed in popular culture. (American) Note for international cities, these terms are English language exonyms, and may not jibe with locals if referring to a foreign city, but often associated with backpackers, and/or expats and tourists.