Greco-Turkish War (1919–1922)
The Greek campaign was launched primarily because the western Allies, particularly British Prime Minister David Lloyd George, had promised Greece territorial gains at the expense of the Ottoman Empire, recently defeated in World War I. The armed conflict started when the Greek forces landed in Smyrna (now Izmir), on 15 May 1919. They advanced inland and took control of the western and northwestern part of Anatolia, including the cities of Manisa, Balıkesir, Aydın, Kütahya, Bursa and Eskişehir. Their advance was checked at the Battle of Sakarya in 1921 by forces of the Turkish national movement. The Greek front collapsed with the Turkish counter-attack in August 1922, and the war effectively ended with the recapture of Smyrna by the Turkish forces and the Great Fire of Smyrna.
Classical Anatolia
For the next 200 years, all of Anatolia came under Achaemenid Persian rule. Their system of local government divided in satrapies in Anatolia allowed many port cities to grow and to become wealthy. Their governors revolted periodically but did not pose a serious threat. In the aftermath of the Greco-Persian Wars, all of Anatolia still remained under Persian control. The Greek Alexander the Great finally wrested control of the whole region from Persia in successive battles, proving victorious over the Persian Darius III. After Alexander's death, his conquests were split amongst several of his trusted generals, but were under constant threat of invasion from both the Gauls and other powerful rulers in Pergamon, Pontus, and Egypt. The Seleucid Empire, the largest of Alexander's territories, and which included Anatolia, became involved in a disastrous war with Rome culminating in the battles of Thermopylae and Magnesia. The resulting Treaty of Apamea in (188 BC) saw the Seleucids retreat from Anatolia. The Kingdom of Pergamum and the Republic of Rhodes, Rome's allies in the war, were granted the former Seleucid lands in Anatolia. Anatolia subsequently became contested between the neighboring rivalling Romans and the Parthian Empire, which frequently culminated in the Roman-Parthian Wars