Missouri
Located in Tornado Alley, Missouri also receives extreme weather in the form of severe thunderstorms and tornadoes. The most recent tornado in the state to cause damage and casualties was the 2011 Joplin tornado, which destroyed roughly one-third of the city of Joplin. The tornado caused an estimated $1–3 billion in damages, killed 159 (+1 non-tornadic), and injured over 1,000 people. It was the first EF5 to hit the state since 1957 and the deadliest in the U.S. since 1947, making it the seventh deadliest tornado in American history and 27th deadliest in the world. St. Louis and its suburbs also have a history of experiencing particularly severe tornadoes, the most recent memorable one being an EF4 tornado that damaged Lambert-St. Louis International Airport on April 22, 2011. One of the worst tornadoes in American history struck St. Louis on May 27, 1896, killing at least 255 and causing $10 mil. damage ($3.9 bil. damage in 2009) or $ in today's dollars.
Tornado outbreak sequence of May 21–26, 2011
A moderate risk of severe weather was issued for much of the Midwest, as well as further south to Oklahoma for May 22. The first tornadic supercell developed in the mid-afternoon hours over the western Twin Cities in Minnesota, and caused moderate damage in the Minneapolis area. Shortly thereafter, an intense tornado crept towards Harmony, Minnesota, prompting the National Weather Service to issue the first tornado emergency of the outbreak. Late that afternoon, a large, intense EF5 multiple-vortex tornado left catastrophic destruction in Joplin, Missouri. Causing 158 fatalities, it was the deadliest single tornado in the U.S. since at least 1947.