Indigenous peoples of the Caribbean
The Classic Taíno lived in eastern Cuba, Hispaniola, and Puerto Rico. They spoke a dialect called Classic Taíno. Compared to their neighbors, the Classic Taíno had substantially developed agricultural societies. Puerto Rico was divided into twenty chiefdoms which were organized into one united kingdom or confederation, Borinquen. Hispaniola was divided into roughly 45 chiefdoms, which were organized into five kingdoms under the leadership of the chief of each area's premier chiefdom. Beginning around 1450, Classic Taíno from Hispaniola began migrating to eastern Cuba; they are conventionally known as the Cuban Taíno. The Cuban Taíno gained power over some of Cuba's earlier Western Taíno inhabitants, the Ciboney, but no regional or island-wide political structure had developed on the island at the time of Spanish colonization of the Americas.
Dominican Republic–Spain relations
The first Europeans to arrive to what is now present day Dominican Republic was in December 1492 when explorer Christopher Columbus arrived to the island of Hispaniola. In 1493, Columbus built one of the first European settlements in the Americas and called it "La Isabela", named after Spanish Queen Isabella I of Castile. Soon after Columbus's arrival to Hispaniola, most of the native Taíno people of the island were wiped out by either diseases brought over from Europe or from direct slaughter by the Spanish. In 1493, the island of Hispaniola was governed under the Captaincy General of Santo Domingo and in 1521, it came under the greater Viceroyalty of New Spain based in Mexico City.