Arachne
It has also been suggested that Jeremias Gotthelf's nineteenth century novella, "The Black Spider", was heavily influenced by the Arachne story from Ovid's "Metamorphoses". In the novella, a woman is turned into a venomous spider having reneged on a deal with the devil.
Medusa (DC Comics)
During the second contest to become Wonder Woman, Diana of Themyscira encountered a serpent-bodied gorgon she believed to be Medusa. This gorgon turned several amazons to stone before being thrown off a cliff by Princess Diana.