Vacuum cleaner
The vacuum cleaner evolved from the carpet sweeper via manual vacuum cleaners. The first manual models, using bellows, were developed in the 1860s, and the first motorized designs appeared at the turn of the 20th century, with the first decade being the boom decade.
Ultracentrifuge
The vacuum ultracentrifuge was invented by Edward Greydon Pickels in the Physics Department at the University of Virginia. It was his contribution of the vacuum which allowed a reduction in friction generated at high speeds. Vacuum systems also enabled the maintenance of constant temperature across the sample, eliminating convection currents that interfered with the interpretation of sedimentation results.