Organophosphate poisoning
Organophosphate pesticides are one of the top causes of poisoning worldwide, with an annual incidence of poisonings among agricultural workers varying from 3-10% per country.
Organobromine compound
Organobromine compounds are the most common organohalides in nature. Even though the concentration of bromide is only 0.3% of that for chloride in sea water, organobromine compounds are more prevalent in marine organisms than organochlorine derivatives. Their abundance reflects the easy oxidation of bromide to the equivalent of Br, a potent electrophile. The enzyme vanadium bromoperoxidase, one of a larger family of bromoperoxidases, catalyzes this reaction in the marine environment. The oceans are estimated to release 1–2 million tons of bromoform and 56,000 tons of bromomethane annually. Red algae, such as the edible "Asparagopsis taxiformis", eaten in Hawaii as "limu kohu", concentrate organobromine and organoiodine compounds in "vesicle cells"; 95% of the essential volatile oil of "Asparagopsis", prepared by drying the seaweed in a vacuum and condensing using dry ice, is organohalogen compounds, of which bromoform comprises 80% by weight. Bromoform, produced by several algae, is a known toxin, though the small amounts present in edible algae do not appear to pose human harm.