Asia
The coastal periphery was home to some of the world's earliest known civilizations, each of them developing around fertile river valleys. The civilizations in Mesopotamia, the Indus Valley and the Yellow River shared many similarities. These civilizations may well have exchanged technologies and ideas such as mathematics and the wheel. Other innovations, such as writing, seem to have been developed individually in each area. Cities, states and empires developed in these lowlands.
Balkans
The Balkan region was the first area in Europe to experience the arrival of farming cultures in the Neolithic era. The Balkans have been inhabited since the Paleolithic and are the route by which farming from the Middle East spread to Europe during the Neolithic (7th millennium BC). The practices of growing grain and raising livestock arrived in the Balkans from the Fertile Crescent by way of Anatolia and spread west and north into Central Europe, particularly through Pannonia. Two early culture-complexes have developed in the region, Starčevo culture and Vinča culture. The Balkans are also the location of the first advanced civilizations. Vinča culture developed a form of proto-writing before the Sumerians and Minoans, known as the Old European script, while the bulk of the symbols had been created in the period between 4500 and 4000 BC, with the ones on the Tărtăria clay tablets even dating back to around 5300 BC.