History of the East–West Schism
Disunion in the Roman Empire further contributed to disunion in the Church. The Emperor Diocletian famously divided the administration of the eastern and western portions of the Empire in the early 4th century, though subsequent leaders (including Constantine) aspired to and sometimes gained control of both regions. Theodosius the Great, who established Nicene Christianity as the official religion of the Roman Empire (see Edict of Thessalonica), was the last Emperor to rule over a united Roman Empire. Following his death in 395, the division into western and eastern halves, each for a few decades still under its own Emperor, was never reunited.
Roman emperor
The last of the Good Emperors, Marcus Aurelius, chose his natural son Commodus as his successor rather than adopting an heir. Commodus's misrule led to his murder on 31 December 192, following which a brief period of instability quickly gave way to Septimius Severus, who established the Severan dynasty which, except for an interruption in 217–218 when Macrinus was emperor, held the purple until 235.