Arachne
It has also been suggested that Jeremias Gotthelf's nineteenth century novella, "The Black Spider", was heavily influenced by the Arachne story from Ovid's "Metamorphoses". In the novella, a woman is turned into a venomous spider having reneged on a deal with the devil.
Avengers Disassembled
The kiss transforms him into her spider-creature. However the kiss has an unexpected side-effect of making him "pregnant", which regressed him back into his human form. As a side-effect, Peter now finds himself able to produce organic spider-webbing from his wrists and has a psychic link with all insects. Peter thwarts the queen's plan of destroying all humans in New York, by disarming a neural bomb. The queen seemingly dies in the collapse of the underground subway.