Persecution of Muslims
The Philippines is predominantly a Christian society with a complicated history of relations between Islam and Christianity. Despite historic evidence of Islamization spreading throughout the islands in the 13th–16th centuries, the archipelago came under Spanish rule in the 16th century. The Spanish proselytized many natives, and labelled those who remained Muslims as "Moro", a derogatory term recalling the Moors, an Islamic people of North Africa who occupied parts of Spain for several centuries. Today, this term "Moro" is used to refer to the indigenous Muslim tribes and ethnic groups of the country. When the Spanish came to the Philippine islands, most of the natives in Luzon and Visayas were pagans with Muslim minorities, and while Spanish proselytized many natives, many Muslims in Luzon and Visayas were not exempted by the Spaniards from the Spanish Inquisition, wherein Muslims to become Catholics or die for their faith. Those who remained Muslims are only the natives of Mindanao and Sulu which the Spaniards did not invade or had control of only briefly and partially.
Spanish East Indies
Seeking to develop trade between the East Indies and the Americas across the Pacific Ocean, Antonio de Mendoza encouraged the exploration of these Asian territories and commissioned the expedition of Ruy López de Villalobos to the Philippines in 1542–1543. Miguel López de Legazpi set out from Mexico, and established the first Spanish settlement in the Philippines in 1565, which became the town of San Miguel in present-day Cebu. That same year, another member of the expedition, Andrés de Urdaneta discovered a maritime route from the Philippines to Mexico, across the Pacific, leading to the important transpacific trade link of the Manila-Acapulco Galleons. In 1571, Manila was captured from the Sultanate of Brunei and then Manila was made the seat of the Spanish Captaincy General of the Philippines. These and other Asian territories claimed by the Spanish crown were to be governed from the Viceroyalty of New Spain in Mexico City.