Eternal sin
Thomas Aquinas lists, or has responded to, six sins that supposedly go against the Holy Spirit:
Thomas Aquinas explains that the unforgivability of blasphemy against the Holy Spirit means that it removes the entrance to these means of salvation; however, it cannot hinder God in taking away this obstacle by way of a miracle.
Christianity and Judaism
Catholicism categorizes sins into various groups. A wounding of the relationship with God is often called venial sin; a complete rupture of the relationship with God is often called mortal sin. Without salvation from sin (see below), a person's separation from God is permanent, causing such a person to enter Hell in the afterlife. Both the Catholic Church and the Orthodox Church define sin more or less as a "macula", a spiritual stain or uncleanliness that constitutes damage to man's image and likeness of God.