Delphi
In 356 BC the Phocians under Philomelos captured and sacked Delphi, leading to the Third Sacred War (356–346 BC), which ended with the defeat of the former and the rise of Macedon under the reign of Philip II. This led to the Fourth Sacred War (339 BC), which culminated in the Battle of Chaeronea (338 BC) and the establishment of Macedonian rule over Greece.
In Delphi, Macedonian rule was superseded by the Aetolians in 279 BC, when a Gallic invasion was repelled, and by the Romans in 191 BC. The site was sacked by Lucius Cornelius Sulla in 86 BC, during the Mithridatic Wars, and by Nero in 66 AD. Although subsequent Roman emperors of the Flavian dynasty contributed towards to the restoration of the site, it gradually lost importance. In the course of the 3rd century mystery cults became more popular than the traditional Greek pantheon. Christianity, which started as yet one more mystery cult, soon gained ground, and this eventually resulted in the persecution of pagans in the late Roman Empire. The anti-pagan legislation of the Flavian dynasty deprived ancient sanctuaries of their assets. The emperor Julian attempted to reverse this religious climate, yet his "pagan revival" was particularly short-lived. When the doctor Oreibasius visited the oracle of Delphi, in order to question the fate of paganism,he received a pessimistic answer:
European balance of power
The papacy launched the Catholic revival in an attempt to halt the growth of Protestantism and put an end to the Ottoman wars in Europe. Despite some successes, such as the Battle of Lepanto (1571) and the Siege of Paris (1590), the Anglo-Spanish War and the Long Turkish War questioned the Catholic ambitions. Ultimately, the Papacy lost its status and influence with the Thirty Years' War and many Protestant states experienced a golden age: the Netherlands (now independent of the Holy Roman Empire) formed the Dutch East India Company in Indonesia; Sweden formed an empire in northern Europe; and England began the colonization of North America. By the Treaty of Westphalia at the end of the Thirty Years War, the Holy Roman Empire became a more decentralized entity in which constituent states, such as Prussia, were allowed to pursue their own foreign policy independent of that of the House of Hapsburg of Austria which continued to rule as Holy Roman Emperor. Hapsburg Austria did directly control some states outside of the Holy Roman Empire. It was France who took the status of dominant continental power from the Habsburgs thanks to the Treaty of Westphalia and the Treaty of the Pyrenees.