Pergamon
Pergamon lies on the north edge of the Caicus plain in the historic region of Mysia in the northwest of Turkey. The Caicus river breaks through the surrounding mountains and hills at this point and flows in a wide arc to the southwest. At the foot of the mountain range to the north, between the rivers Selinus and Cetius, there is the massif of Pergamon which rises 335 metres above sea level. The site is only 26 km from the sea, but the Caicus plain is not open to the sea, since the way is blocked by the Karadağ massif. As a result, the area has a strongly inland character. In Hellenistic times, the town of Elaia at the mouth of the Caicus served as the port of Pergamon. The climate is Mediterranean with a dry period from May to August, as is common along the west coast of Asia Minor.
Pergamon
Yet it was only under Trajan and his successors that a comprehensive redesign and remodelling of the city took place, with the construction a Roman 'new city' at the base of the Acropolis. The city was the first in the province to receive a second neocorate, from Trajan in AD 113/4. Hadrian raised the city to the rank of metropolis in 123 and thereby elevated it above its local rivals, Ephesus and Smyrna. An ambitious building programme was carried out: massive temples, a stadium, a theatre, a huge forum and an amphitheatre were constructed. In addition, at the city limits the shrine to Asclepius (the god of healing) was expanded into a lavish spa. This sanctuary grew in fame and was considered one of the most famous therapeutic and healing centers of the Roman world. In the middle of the 2nd century, Pergamon was one of the largest cities in the province, along with these two, and had around 200,000 inhabitants. Galen, the most famous physician of antiquity aside from Hippocrates, was born at Pergamon and received his early training at the Asclepeion. At the beginning of the third century, Caracalla granted the city a third neocorate, but the decline had already set in. During the crisis of the Third Century, the economic strength of Pergamon finally collapsed, as the city was badly damaged in an earthquake in 262 and was sacked by the Goths shortly thereafter. In late antiquity, it experienced a limited economic recovery.