Christianity in Turkey
Constantinople became established in the ecclesiastical hierarchy at the Council of Constantinople in 381. Second only to Rome, the legendary origins of the Patriarchate of Constantinople go back to St. Andrew, Metrophanes and Alexander of Constantinople. Constantinople's primacy over the Patriarchates of Alexandria and Antioch was reaffirmed at the Council of Chalcedon in 481, after which the papacy in Rome supported Constantinople in its dispute with Alexandria over monophysitism. Later, when Rome sought to assert its primacy over Byzantium, the Eastern Orthodox church developed the doctrine of pentarchy as a response.
Classical Anatolia
Roman control of Anatolia was strengthened by a 'hands off' approach by Rome, allowing local control to govern effectively and providing military protection. In the early 4th century, Constantine the Great established a new administrative centre at Constantinople, and by the end of the 4th century a new eastern empire was established with Constantinople as its capital, referred to by historians as the Byzantine Empire from the original name, Byzantium.