Seikilos epitaph
The Seikilos epitaph is the oldest surviving complete musical composition, including musical notation, from anywhere in the world. The epitaph has been variously dated, but seems to be either from the 1st or the 2nd century AD. The song, the melody of which is recorded, alongside its lyrics, in the ancient Greek musical notation, was found engraved on a tombstone (a stele) from the Hellenistic town Tralles near present-day Aydın, Turkey, not far from Ephesus. It is a Hellenistic Ionic song in either the Phrygian octave species or Iastian tonos. While older music with notation exists (for example the Hurrian songs), all of it is in fragments; the Seikilos epitaph is unique in that it is a complete, though short, composition.
Claudio Veggio
Of greatest significance to musicologists is a manuscript by Veggio which survived in the archives of Castell'Arquato. It appears to be a rough copy of his draft compositions, containing numerous sketches, strikeouts and revisions; it is one of the earliest such music manuscripts to survive, and provides a rare window into compositional procedures of the time. Many of the compositions are transcriptions for keyboard of vocal compositions, now lost, probably by other composers.