Eternal sin
Thomas Aquinas lists, or has responded to, six sins that supposedly go against the Holy Spirit:
Thomas Aquinas explains that the unforgivability of blasphemy against the Holy Spirit means that it removes the entrance to these means of salvation; however, it cannot hinder God in taking away this obstacle by way of a miracle.
LGBT rights opposition
Passages in the Old Testament that prohibit man "lie with mankind as with womankind" and the story of Sodom and Gomorrah have historically been interpreted as condemning sodomy. Several Pauline passages have also been cited against male and female homosexuality. Christians who take a conservative position on homosexuality endorse this reading of these passages in the belief that God is against same-sex sexual activity, while Christians who take a liberal position believe that these same passages refer to more specific situations, such as rape or abuse, and not homosexuality. The largest Christian body, the Catholic Church, condemns homosexual acts as "gravely sinful" and "intrinsically disordered". The second-largest Christian body, the Eastern Orthodox Church, also condemns homosexual behaviour, as do most denominations of Protestantism.