Andean natural region
The Andes mountains form the most populated region of Colombia and contain the majority of the country's urban centers. They were also the location of the most significant pre-Columbian indigenous settlements. Beyond the Colombian Massif in the south-western departments of Cauca and Nariño, the Colombian Andes divide into three branches known as "cordilleras" (from the Spanish for "mountain range"): the West Andes run adjacent to the Pacific coast and is home to the city of Cali. The Central Andes run up the center of the country between the Cauca and Magdalena river valleys (to the west and east respectively) and includes the cities of Medellín, Manizales and Pereira. The East Andes extend northeast towards the Guajira Peninsula, and includes the cities of Bogotá, Bucaramanga and Cúcuta.
Plateau
The parallel Sierra of Andes delimit one of the world highest plateaux: the Altiplano, (Spanish for "high plain"), Andean Plateau or Bolivian Plateau. It lies in west-central South America, where the Andes are at their widest, is the most extensive area of high plateau on Earth outside of Tibet. The bulk of the Altiplano lies within Bolivian and Peruvian territory while its southern parts lie in Chile. The Altiplano plateau hosts several cities like Puno, Oruro, El Alto and La Paz the administrative seat of Bolivia. Northeastern Altiplano is more humid than the Southwestern, the latter of which hosts several salares, or salt flats, due to its aridity. At the Bolivia-Peru border lies Lake Titicaca, the largest lake in South America.