Arachne
It has also been suggested that Jeremias Gotthelf's nineteenth century novella, "The Black Spider", was heavily influenced by the Arachne story from Ovid's "Metamorphoses". In the novella, a woman is turned into a venomous spider having reneged on a deal with the devil.
Inheritors (comics)
Karn comes to Earth-3123 to kill the spider-totem of the reality where Aunt May was bitten by a radioactive spider and became Spider-Ma'am. She surrenders herself to keep her husband and nephew from harm. Karn is turned by Spider-Girl, Spider-UK, Spider-Punk, Spider-Man: India, and Spider-Woman of Earth-807128 against the Inheritors. After Black Widow of Earth-1610 and Kaine destroy the cloning facility on Earth-802, the Inheritors attack; Kaine arrives on Earth-001, transforms into a spider and impales Solus.