Cutaneous respiration
The skin of amphibians is a major site of respiration in all species for which measurements are available. Cutaneous respiration is the sole respiratory mode of lungless salamanders (family Plethodontidae) which lack lungs entirely yet constitute the largest family of salamanders. Cutaneous respiration in frogs and other amphibians may be the primary respiratory mode during colder temperatures.
Green-eyed tree frog
Peptides found within the skin of frogs, including the green-eyed species, are now being looked to for HIV virus prevention. The chemicals found within their skin aren't pleasant for their predators, but can be very useful when fighting against bacteria, viruses, and fungus. When in dendritic cells, it has been found that the virus can still be killed by these peptides, showing a promise for mucosal preventatives. What is needed now, is the identification of which peptides can exactly prevent HIV in order to put this to work.