Afro-Panamanian
In 1904 when the construction of the Panama Canal was taken over by the United States for the failure of the French company, will again resort to the West Indian worker. Although between 1904 and 1914 the vast majority of Afro-West Indians who arrived in Panama did a one-year contract with the idea of returning to their home islands once the offshore project, after construction of the canal many Afro-Antillean stayed in Panama. Afro-West Indians who remained in Panama many got jobs in the Canal Zone and became the largest immigrant group in Panama. On the subject of Afro-Antillean Panama, Leslie B. Rout said that when the canal was opened in 1914, some 20,000 African-West Indians remained in Panama.
Hay–Bunau-Varilla Treaty
Bunau-Varilla was originally involved in the building of the Panama Canal under Ferdinand de Lesseps, who had built the Suez Canal. After the collapse of the de Lesseps efforts to build the Panama Canal, Bunau-Varilla became an important shareholder of the "Compagnie Nouvelle du Canal de Panama", which still had the concession, as well as certain valuable assets, for the building of a canal in Panama. Although not Panamanian himself, Bunau-Varilla had provided financial assistance to the rebel side in Panama's independence from Colombia, which occurred two weeks prior to the signing of the treaty. He had not, however, been in Panama for seventeen years, nor had he ever returned. As part of the Hay–Bunau-Varilla negotiations, the U.S. bought the shares and assets of the "Compagnie Nouvelle du Canal de Panama" for US$40 million.