Episteme
"Episteme" is a philosophical term derived from the Ancient Greek word ἐπιστήμη "epistēmē", which can refer to knowledge, science or understanding, and which comes from the verb , meaning "to know, to understand, or to be acquainted with".
Encyclopedia
In the sixteenth century there was a level of ambiguity as to how to use this new word. As several titles illustrate, there was not a settled notion about its spelling nor its status as a noun. For example: Jacobus Philomusus's ' (1508); Johannes Aventinus's '; Joachimus Fortius Ringelbergius's ' (1538, 1541); Paul Skalich's ' (1559); Gregor Reisch's ' (1503, retitled Encyclopaedia in 1583); and Samuel Eisenmenger's ' (1585). It is only with Pavao Skalić and his "" (Encyclopaedia, or Knowledge of the World of Disciplines, Basel, 1559) that the term became first recognized as a noun.