Cutaneous respiration
The skin of amphibians is a major site of respiration in all species for which measurements are available. Cutaneous respiration is the sole respiratory mode of lungless salamanders (family Plethodontidae) which lack lungs entirely yet constitute the largest family of salamanders. Cutaneous respiration in frogs and other amphibians may be the primary respiratory mode during colder temperatures.
Excretory system
In mammals. the skin excretes sweat through sweat glands throughout the body. The sweat, helped by salt, evaporates and helps to keep the body cool when it is warm. In amphibians, the lungs are very simple, and they lack the necessary means to the exhale like other tetrapods can. The moist, scale-less skin is therefore essential in helping to rid the blood of carbon dioxide, and also allows for urea to be expelled through diffusion when submerged.