IPLEDGE program
Although the goal of the program is to prevent pregnancies of women who take the drug, male patients must also participate in anti-pregnancy restrictions, primarily due to fears that male isotretinoin users might share their prescriptions with females without their physicians' knowledge. There has been no link to birth defects from Accutane associated with males using the drug, though male sexual dysfunction has been suggested by one study. As this has not been conclusively proven, this is not acknowledged as a side effect in the official literature accompanying the medication.
Ceftazidime/avibactam
Ceftazidime/avibactam (CAZ-AVI) is a fixed-dose combination drug containing an antibiotic—3rd generation cephalosporin ceftazidime and a novel non-β-lactam β-lactamase inhibitor avibactam. It was approved for use in the United States in February 2015, and is sold under the brand name Avycaz, marketed by Allergan. In Europe, it was approved by the European Medicines Agency in 2016 and is sold as Zavicefta.