Cutaneous respiration
The skin of amphibians is a major site of respiration in all species for which measurements are available. Cutaneous respiration is the sole respiratory mode of lungless salamanders (family Plethodontidae) which lack lungs entirely yet constitute the largest family of salamanders. Cutaneous respiration in frogs and other amphibians may be the primary respiratory mode during colder temperatures.
Epicauta vittata
Frogs are apparently not affected by Meloidae beetle toxin, and "consume meloids with impunity". After eating blister beetles, frogs retain the toxin in their tissues and secrete it in their mucus for a short time, and predators that consume the frogs can be poisoned. This includes humans who consume foods such as frog legs. Northern leopard frogs fed striped blister beetles in studies accumulated cantharidin in their thigh muscles, among other tissues. It is estimated that as little as 200 grams of frog legs from beetle-fed frogs could contain a potentially fatal dose of toxin.