Arachne
It has also been suggested that Jeremias Gotthelf's nineteenth century novella, "The Black Spider", was heavily influenced by the Arachne story from Ovid's "Metamorphoses". In the novella, a woman is turned into a venomous spider having reneged on a deal with the devil.
White Tiger (Heroes for Hire)
When the High Evolutionary mutated a wolf into a powerful creature called the Man-Beast, his creation turned evil, and escaped. High Evolutionary created a second altered animal to catch his rogue wolf. He mutated a white Bengal tigress into a woman, whom he named the White Tiger. White Tiger's bestial origins gave her cat-like speed and reflexes, and she was highly skilled in martial arts. On her quest to find Man-Beast, White Tiger joined a team of villains called the U-Foes, and fell in love with their leader, Vector. When the U-Foes attacked a supervillain prison, White Tiger left the team, and searching for heroes to help her, found Iron Fist. She was intrigued by him, and joined his team Heroes for Hire. White Tiger tried to keep her origins a secret, but during a training session with Iron Fist, he defeated her several times in mock combat. Her anger overwhelmed her, and she lost control and reverted to her tiger form. She feared that the others would shun her for her animal-nature, but they accepted her as part of the team.