Margherita Colonna
She was born in Palestrina about 1255. Her father, Oddone Colonna, died when she was about two years old. Her mother, who was also named Margherita and who was the sister of Matteo Rosso Orsini and a pious woman, died when Margherita was probably a little over ten years old. Margherita was left in the care of her older brothers.
Palestine (region)
In the 330s BCE, Macedonian ruler Alexander the Great conquered the region, which changed hands several times during the wars of the Diadochi and later Syrian Wars. It ultimately fell to the Seleucid Empire between 219–200 BCE. In 116 BCE, a Seleucid civil war resulted in the independence of certain regions including the Hasmonean principality in the Judaean Mountains. From 110 BCE, the Hasmoneans extended their authority over much of Palestine, creating a Judaean–Samaritan–Idumaean–Ituraean–Galilean alliance. The Judaean (Jewish, see Ioudaioi) control over the wider region resulted in it also becoming known as Judaea, a term that had previously only referred to the smaller region of the Judaean Mountains. Between 73–63 BCE, the Roman Republic extended its influence into the region in the Third Mithridatic War, conquering Judea in 63 BCE, and splitting the former Hasmonean Kingdom into five districts. In around 40 BCE, the Parthians conquered Palestine, deposed the Roman ally Hyrcanus II, and installed a puppet ruler of the Hasmonean line known as Antigonus II. By 37 BCE, the Parthians withdrew from Palestine. The three-year Ministry of Jesus, culminating in his crucifixion, is estimated to have occurred from 28–30 CE, although the historicity of Jesus is disputed by a minority of scholars. In 70 CE, Titus sacked Jerusalem, resulting in the dispersal of the city's Jews and Christians to Yavne and Pella. In 132 CE, Hadrian joined the province of Iudaea with Galilee and the Paralia to form new province of Syria Palaestina, and Jerusalem was renamed "Aelia Capitolina". Between 259–272, the region fell under the rule of Odaenathus as King of the Palmyrene Empire. Following the victory of Christian emperor Constantine in the Civil wars of the Tetrarchy, the Christianization of the Roman Empire began, and in 326, Constantine's mother Saint Helena visited Jerusalem and began the construction of churches and shrines. Palestine became a center of Christianity, attracting numerous monks and religious scholars. The Samaritan Revolts during this period caused their near extinction. In 614 CE, Palestine was annexed by another Persian dynasty; the Sassanids, until returning to Byzantine control in 628 CE.