Plasmodium falciparum
Plasmodium falciparum is a unicellular protozoan parasite of humans, and the deadliest species of "Plasmodium" that cause malaria in humans. It is transmitted through the bite of a female "Anopheles" mosquito. It is responsible for roughly 50% of all malaria cases. It causes the disease's most dangerous form called falciparum malaria. It is therefore regarded as the deadliest parasite in humans, causing 435,000 deaths in 2017. It is also associated with the development of blood cancer (Burkitt's lymphoma) and is classified as Group 2A carcinogen.
Culex quinquefasciatus
The southern house mosquito transmits zoonotic diseases that affect humans and wild and domestic animals, such as lymphatic filariasis, avian malaria, St. Louis encephalitis, Western equine encephalitis, and West Nile fever, and may be a vector of the Zika virus. It causes infection through biting during blood meal. In the southern U.S., it is the primary vector of St. Louis encephalitis virus. In India and Southeast Asia, it is the primary vector of "Wuchereria bancrofti", a nematode that causes lymphatic filariasis. It acts as an intermediate host for the helminth parasite by harbouring the larval stages. It also transmits "Plasmodium relictum", a malarial parasite of birds, and is its principal vector in Hawaii. It is the definitive host for the malarial parasite as it harbours the sexual cycle.