Eternal sin
Thomas Aquinas lists, or has responded to, six sins that supposedly go against the Holy Spirit:
Thomas Aquinas explains that the unforgivability of blasphemy against the Holy Spirit means that it removes the entrance to these means of salvation; however, it cannot hinder God in taking away this obstacle by way of a miracle.
Seven deadly sins
Pope Gregory combined this with "tristitia" into sloth for his list. When Thomas Aquinas described "acedia" in his interpretation of the list, he described it as an "uneasiness of the mind", being a progenitor for lesser sins such as restlessness and instability. Dante refined this definition further, describing acedia as the "failure to love God with all one's heart, all one's mind and all one's soul"; to him it was the "middle sin", the only one characterised by an absence or insufficiency of love. Some scholars have said that the ultimate form of acedia was despair which leads to suicide.