Oxytocin
It has been shown that oxytocin differentially affects males and females. Females who are administered oxytocin are overall faster in responding to socially relevant stimuli than males who received oxytocin. Additionally, after the administration of oxytocin, females show increased amygdala activity in response to threatening scenes; however, males do not show increased amygdala activation. This phenomenon can be explained by looking at the role of gonadal hormones, specifically estrogen, which modulate the enhanced threat processing seen in females. Estrogen has been shown to stimulate the release of oxytocin from the hypothalamus and promote receptor binding in the amygdala.
Oxymoron (album)
In February 2014, during a Q&A session for the album, at SONOS Studios in Los Angeles, California, Schoolboy Q described the song "Prescription/Oxymoron", as the most personal: "I came up selling OxyContin," he said. "The karma behind it was that I never took an OxyContin before but I did get addicted to Percocets, Xanax, Codeine—shit like that. When my daughter was one and two [years old], I used to get into sleep comas, like 'Xan comas'—just dead to the world and I put it into the music." Schoolboy Q said he arranged the song to juxtapose the process of selling prescription pills and addiction: "I put the OxyContin and selling it at the end of the relapse or the addiction," he said. "I sold OxyContin and then I got addicted [to pills]. This way, I showed that I got addicted then I sold it. That was a crazy record. That's true shit—the first part of it when my daughter tried to wake me up and I was dead to the world. That was my little secret. I always had the cup with me. They just never knew I had a gang of pills in the other bottle. That was a little story about me and how I was addicted, too."