Asim Shahmalak
He is a frequent media spokesman, and has written about the importance placed in hair over the centuries and the fact that baldness until recently was not recognised as a social or medical issue, despite the sometimes catastrophic impact it can have on confidence and mental well-being. He wrote: "Male pattern baldness (MPB), the main cause of hair loss, affects an estimated quarter of men by the age of 30 and two thirds by the age of 60. Until recently, the impact baldness might have on confidence and well-being was little understood or recognised by the medical profession at large."
5α-Reductase deficiency
In adulthood, individuals do not experience male-pattern baldness. As dihydrotestosterone (DHT) is a far more potent androgen than testosterone alone, virilization in those lacking DHT may be absent or reduced compared to males with functional 5-AR. It is hypothesized that rising testosterone levels at the start of puberty are able to generate sufficient levels of DHT either by the action of 5α-reductase type I (active in the adult liver, non-genital skin and some brain areas) or through the expression of low levels of 5α-reductase type II in the testes.