Christopher Columbus
Since the late 20th century, historians have criticized Columbus for initiating colonization and for abuse of natives. Among reasons for this criticism is the poor treatment of the native Taíno people of Hispaniola, whose population declined rapidly after contact with the Spanish. Columbus required the natives to pay tribute in gold and cotton. Modern estimates for the pre-Columbian population of Hispaniola are around 250,000–300,000. According to the historian Gonzalo Fernandez de Oviedo y Valdes, by 1548, 56 years after Columbus landed, and 42 years after he died, fewer than 500 Taíno were living on the island. The indigenous population declined rapidly, due primarily to the first pandemic of European endemic diseases, which struck Hispaniola after 1519. The natives had no acquired immunity to these new diseases and suffered high fatalities. There is also documentation that they were overworked.
Patagonia
The indigenous peoples of the region included the Tehuelches, whose numbers and society were reduced to near extinction not long after the first contacts with Europeans. Tehuelches included the Gununa'kena to the north, Mecharnuekenk in south central Patagonia and the Aonikenk or Southern Tehuelche in the far South, north of the Magellan strait. On Isla Grande de Tierra del Fuego, the Selk'nam (Ona) and Haush (Manek'enk) lived in the north and south east respectively. In the archipelagos to the south of Tierra del Fuego were Yámana, with the Kawéskar (Alakaluf) in the coastal areas and islands in western Tierra del Fuego and the south west of the mainland. In the Patagonian archipelagoes north of Taitao Peninsula lived the Chonos. These groups were encountered in the first periods of European contact with different lifestyles, body decoration and language, although it is unclear when this configuration emerged.