History of the East–West Schism
Disunion in the Roman Empire further contributed to disunion in the Church. The Emperor Diocletian famously divided the administration of the eastern and western portions of the Empire in the early 4th century, though subsequent leaders (including Constantine) aspired to and sometimes gained control of both regions. Theodosius the Great, who established Nicene Christianity as the official religion of the Roman Empire (see Edict of Thessalonica), was the last Emperor to rule over a united Roman Empire. Following his death in 395, the division into western and eastern halves, each for a few decades still under its own Emperor, was never reunited.
Culture of ancient Rome
The Roman Empire, at its height (c. 117 CE), was the most extensive political and social structure in western civilization. By 285 CE the empire had grown too vast to be ruled from the central government at Rome and so was divided by Emperor Diocletian into a Western and an Eastern Empire. The Roman Empire began when Augustus Caesar became the first emperor of Rome (31 BCE) and ended, in the west, when the last Roman emperor, Romulus Augustulus, was deposed by the Germanic King Odoacer (476 CE). In the east, it continued as the Byzantine Empire until the death of Constantine XI and the fall of Constantinople to the Ottoman Turks in 1453 CE. The influence of the Roman Empire on western civilization was profound in its lasting contributions to virtually every aspect of western culture.