Christopher Columbus
Since the late 20th century, historians have criticized Columbus for initiating colonization and for abuse of natives. Among reasons for this criticism is the poor treatment of the native Taíno people of Hispaniola, whose population declined rapidly after contact with the Spanish. Columbus required the natives to pay tribute in gold and cotton. Modern estimates for the pre-Columbian population of Hispaniola are around 250,000–300,000. According to the historian Gonzalo Fernandez de Oviedo y Valdes, by 1548, 56 years after Columbus landed, and 42 years after he died, fewer than 500 Taíno were living on the island. The indigenous population declined rapidly, due primarily to the first pandemic of European endemic diseases, which struck Hispaniola after 1519. The natives had no acquired immunity to these new diseases and suffered high fatalities. There is also documentation that they were overworked.
Indigenous people of the Everglades region
The first contact with Spanish explorers occurred in 1513 when Juan Ponce de León stopped at a bay he called "Chequescha", or Biscayne Bay. Finding the Tequesta unwelcoming, he left to make contact with the Calusa. Menéndez met the Tequesta in 1565 and maintained a friendly relationship with them, building some houses and setting up a mission. He also took the chief's nephew to Havana to be educated, and the chief's brother to Spain. After Menéndez visited, there are few records of the Tequesta: a reference to them in 1673, and further Spanish contact to convert them. The last reference to the Tequesta during their existence was written in 1743 by a Spanish priest named Father Alaña, who described their ongoing assault by another tribe. The survivors numbered only 30, and the Spanish transported them to Havana. In 1770 a British surveyor described multiple deserted villages in the region where the Tequesta had lived. Archeologist John Goggin suggested that by the time European Americans settled the area in 1820, any remaining Tequesta were assimilated into the Seminole people. Common descriptions of Native Americans in Florida by 1820 identified only the "Seminoles".