Organophosphate poisoning
Organophosphate pesticides are one of the top causes of poisoning worldwide, with an annual incidence of poisonings among agricultural workers varying from 3-10% per country.
Folate
When the U.S. Food and Drug Administration set the folic acid fortification regulation in 1996, the projected increase in folic acid intake was 100 µg/d. Mandatory fortification began 1 January 1998. The U.S. National Center for Health Statistics conducts biannual National Health and Nutrition Examination Survey (NHANES) to assess the health and nutritional status of adults and children in the United States. Some results are reported as What We Eat In America. The 2013–2014 survey reported that for adults ages 20 years and older, men consumed on average of 249 μg/d folate from food plus 207/d μg of folic acid from consumption of fortified foods, for a combined total of 601 μg/d of dietary folate equivalents (DFEs; because each microgram of folic acid counts as 1.7 μg of food folate). For women, the values are 199, 153 and 459 μg/d, respectively. This means that fortification led to a bigger increase in folic acid intake than first projected, and that more than half the adults are consuming more than the RDA of 400 μg (as DFEs), but even so, fewer than half of pregnant women are exceeding the pregnancy RDA of 600 μg/d.