KHII-TV
On March 7, 2006, Raycom Media announced that KFVE would affiliate with MyNetworkTV as part of a group deal involving many of Raycom-owned affiliates of The WB and UPN (whose consolidation and shutdowns the following September resulted in the creation of The CW Television Network, which would affiliate in Hawaii with a digital subchannel of KHON-TV). KFVE officially joined MyNetworkTV on September 5, 2006 and did not air The WB's final two weeks of prime-time programming (though it continued to air WB daytime and Saturday morning programming until the end of the network's existence).
The CW
On May 23, 2016, The CW and Tribune announced they had come to a new affiliation agreement. As part of the deal, Tribune's Chicago flagship WGN-TV would leave the network and revert to being an independent station after nearly 21 years of being affiliated with The CW and its predecessor network, The WB. A major factor in this decision is WGN-TV's large use of local sports programming, which led to many pre-emptions of the CW while WGN-TV has had to move as many as 30 games a year to another local station in Chicago. The CW affiliation moved to WPWR-TV, a Fox Television Stations-owned MyNetworkTV station.