Prothoracicotropic hormone
Prothoracicotropic hormone (PTTH) was the first insect hormone to be discovered. It was originally described simply as "brain hormone" by early workers such as Stefan Kopeć (1922) and Vincent Wigglesworth (1934), who realized that ligation of the head of immature insects could prevent molting or pupation of the body region excluded from the head if the ligation was performed before a critical age in the lifestage was reached. After a certain point the ligation had no effect and both sections of the insect would molt or pupate. However, implantation of a conspecific brain to a sessile ligated abdomen or an abdomen under diapause would induce molting or pupation. Thus, the brain was originally thought to be the source of the hormone that induces molting in insects.
Florey Institute of Neuroscience and Mental Health
The Institute was formally established in 1971 by the Victorian Government and named in honour of Howard Florey, an Australian Laureate of the 1945 Nobel Prize in Medicine who helped to isolate the active principle of penicillin and developed the first manufacturing process for the antibiotic. The Institute conducted research into physiological control of body fluid and electrolyte balance, especially the regulation of the adrenal salt-retaining hormone, aldosterone; micro measurement of hormones; hybridization histochemistry; instincts that control ingestion; and the Relaxin hormone.