U.S. Route 101
The nearly highway's northern terminus is in Tumwater, Washington: the route remains along the Olympic Peninsula's coastal perimeter west, north, and east; the northernmost point on the highway is in Port Angeles. The southern terminus of US 101 is in Los Angeles at the East Los Angeles Interchange, the world's busiest freeway interchange.
Indiana State Road 101
The third portion of SR 101 is long and starts at US 52 and SR 1 in Brookville. SR 101 runs concurrent with SR 1 north and then SR 101 heads northeast, leaving SR 1. The highway curves around Brookville Lake and continues due north towards Liberty. The road crosses into Union County and turns northeast again, ending at an intersection with US 27 and SR 44 in Liberty.