Chameleon (comics)
Created by writer Stan Lee and artist Steve Ditko, the character first appeared in "The Amazing Spider-Man" #1 (March 1963), making him the first member of Spider-Man's rogues' gallery, based on issue publication date, excluding the burglar who murdered Ben Parker (Supercharger was the first Spider-Man supervillain chronologically). He is also well known to be related to Kraven the Hunter. That revealed relationship helped evolve him as a major villain compared to his original depiction of being just a solo villain in the original issue of "The Amazing Spider-Man".
Chameleon (comics)
After Spider-Man and the Black Widow escape with the help of Silver Sable, Chameleon suggest that since the remaining members of the Sinister Six had each received their $2 billion and their criminal records expunged, they should just leave Doctor Octopus and his scheme. However, they stay on board as that would make an enemy out of Doctor Octopus. The Chameleon later gets involved with Mysterio in tricking Spider-Man and his allies into thinking they were destroying Symkaria, in order to give Doctor Octopus more time to complete his 200 satellites. However, the Chameleon is captured and the Black Widow threatens to reveal the secret behind his real face.