Arachne
It has also been suggested that Jeremias Gotthelf's nineteenth century novella, "The Black Spider", was heavily influenced by the Arachne story from Ovid's "Metamorphoses". In the novella, a woman is turned into a venomous spider having reneged on a deal with the devil.
Spider-Gwen
Prior to the beginning of Spider-Gwen, high school student Gwen Stacy was bitten by a radioactive spider. This granted her all of the quintessential Spider-Man powers, and Stacy began her career as Spider-Woman. In her regular life, she began a relationship with Peter Parker and formed a friend group with Parker and ostracized new student Harry Osborn, who is later revealed to have had a crush on her. Meanwhile, Peter began his infatuation with Spider-Woman — without knowing that she is secretly his best friend Gwen Stacy. The bullied Peter's suffering worsens, and eventually, he creates a formula that turns him into a lizard mutant.