Indigenous peoples of the Caribbean
The Classic Taíno lived in eastern Cuba, Hispaniola, and Puerto Rico. They spoke a dialect called Classic Taíno. Compared to their neighbors, the Classic Taíno had substantially developed agricultural societies. Puerto Rico was divided into twenty chiefdoms which were organized into one united kingdom or confederation, Borinquen. Hispaniola was divided into roughly 45 chiefdoms, which were organized into five kingdoms under the leadership of the chief of each area's premier chiefdom. Beginning around 1450, Classic Taíno from Hispaniola began migrating to eastern Cuba; they are conventionally known as the Cuban Taíno. The Cuban Taíno gained power over some of Cuba's earlier Western Taíno inhabitants, the Ciboney, but no regional or island-wide political structure had developed on the island at the time of Spanish colonization of the Americas.
Hispaniola
Under Nicolás de Ovando y Cáceres' governorship, the Indians were made to work in the gold mines. By 1503, the Spanish Crown legalized the distribution of Indians to work the mines as part of the encomienda system. Once the Indians entered the mines, they were often wiped out by hunger and difficult conditions. By 1508, the Taíno population of about 400,000 was reduced to 60,000, and by 1514, only 26,334 remained. About half resided in the mining towns of Concepcion, Santiago, Santo Domingo, and Buenaventura. The repartimiento of 1514 accelerated emigration of the Spanish colonists, coupled with the exhaustion of the mines. The first documented outbreak of smallpox, previously an Eastern hemisphere disease, occurred on Hispaniola in December 1518 among enslaved African miners. Some scholars speculate that European diseases arrived before this date, but there is no compelling evidence for an outbreak. The natives had no immunity to European diseases, including smallpox. By May 1519, as many as one-third of the remaining Taínos had died.