Orientia tsutsugamushi
"O. tsutsugamushi" causes a complex and dangerous infection scrub typhus. Infection starts when chiggers bite on the skin during their feeding. The bacteria are deposited at the site of feeding (inoculation), where they multiply. They cause progressive tissue damage (necrosis). Necrosis progresses to inflammation of the blood vessels called vasculitis. This in turn causes inflammation of the lymph nodes, called lymphadenopathy. Within a few days, vasculitis extends to various organs including liver, brain, kidney, meninges and the lung. The disease is responsible for nearly a quarter of all the febrile (high fever) illness in endemic areas. Mortality in severe case or due to improper treatment or misdiagnosis may be as high as 30-70%. About 6% of infected people die untreated, and 1.4% of the patients die even with medical treatment. Moreover, death rate can be as high as 13% where medical treatment is not properly handled. In cases of misdiagnosis and failure of treatment, systemic complications rapidly develop including acute respiratory distress syndrome, acute kidney failure, encephalitis, gastrointestinal bleeding, hepatitis, meningitis, myocarditis, pancreatitis, pneumonia, septic shock, sub-acute thyroiditis, and multi-organ dysfunctions. Harmful symptoms involving multiple organ failure and neurological impairment are difficult to treat, and can be lifelong debilitation or directly fatal. The central nervous system is often affected and result in various complications including cerebellitis, cranial nerve palsies, meningoencephalitis, plexopathy, transverse myelitis, neuroleptic malignant syndrome, and Guillan-Barré syndrome. Death rates due to complications can be up to 14% in brain infections, and 24% with multiple organ failure. It is the major cause of acute encephalitis syndrome in India, where viral infection Japanese encephalitis has been regarded as the main factor.
Maraka (Hindu astrology)
The manner of death can be known from the yoga-formations occurring at the time of birth, e.g. if the Sun combines with Saturn and Rahu in the 7th house the person will be bitten by a cobra or if the Sun and Mars are in the 4th house aspected by or in conjunction with the lord of the 4th and the 10th, the person will be stoned to death or die by falling on a stone or by a falling stone. Death from punishment by ruler can occur if the Sun is in the 3rd or is influencing the lord of the 3rd house or by fire if it in the 8th or influencing the 8th house; similarly the Moon can cause death either by Tuberculosis or from excess fluids (or drowning); Mars from either a surgical operation, burns, injuries or from weapon or surgery; Mercury from either Febrile, illness, or from fever; Jupiter from either Tumours, swelling or from prolonged illness; Venus from either Diabetes or renal disease or from starvation; and Saturn and Rahu from poison, drowning, fall from height, injury, incarceration or from thirst or dehydration. Natural malefics cause illness or death in their dasha or antradasha; disease is possible in the body that is susceptible to diseases; a strong lagna and the strong lord of the lagna, and the natural benefics in the kendras prevent early or pre-mature death caused by illness or disease.