Chameleon (comics)
Following the "Dying Wish" storyline, Chameleon later fights Superior Spider-Man (Otto Octavius's mind in Spider-Man's body) and the Secret Avengers on the S.H.I.E.L.D. Helicarrier. Chameleon ends up knocked unconscious and Superior Spider-Man transports him to his hidden underwater lab where he ends up imprisoned. Chameleon, Electro, Sandman, Mysterion, and the Vulture are later seen as part of a team led by Superior Spider-Man called the "Superior Six". Superior Spider-Man has been temporarily controlling their minds in order to redeem them for their crimes. He does this by forcing them do heroic deeds against their will which almost get some of them killed. Every time he is done controlling them, he puts them back in their containment cells. They eventually break free of Superior Spider-Man's control and attempt to exact revenge on the wall-crawler, while nearly destroying New York in order to do so. With the help of Sun Girl, Superior Spider-Man is barely able to stop the Superior Six.
Chameleon (comics)
The Chameleon's most ambitious play against Spider-Man happened when he formed an alliance with Harry Osborn as the Green Goblin. Before Harry's death, he told Chameleon Spider-Man's secret identity could be found through Peter Parker, to construct androids of Peter's parents; Chameleon later admitted that he went through with the plot to confirm once and for all that Peter was Spider-Man. The plan led to a psychotic breakdown for both Spider-Man and Chameleon, Spider-Man briefly renouncing his civilian identity while Chameleon is sent to Ravencroft Asylum. However, when Doctor Ashley Kafka sneaks him into a basement to try to continue treating him in the belief that he was close to a breakthrough when the court were preparing to put him on trial, Chameleon escaped and attempted to convince Spider-Man that he was actually a hallucinating writer who had suffered a mental breakdown after his daughter's death in a car accident, but Peter managed to break through this deception due to his own strength of will. Chameleon's confirmation of Spider-Man's secret identity led him to try to attack Spider-Man through his family and friends, but this effort met with rather dismal results when Mary Jane Watson subdued him with a baseball bat. Somewhere in between this and subsequent appearances, he appeared to have been destroyed by his nephew Alyosha Kravinoff; Alyosha later threw a Chameleon mask at Spider-Man's feet, referring to it as 'That weakling Dmitri' but apparently recovered, waking in a hospital.