Medical ultrasound
A contrast medium for medical ultrasonography is a formulation of encapsulated gaseous microbubbles to increase echogenicity of blood, discovered by Dr Raymond Gramiak in 1968 and named contrast-enhanced ultrasound. This contrast medical imaging modality is clinically used throughout the world, in particular for echocardiography in the United States and for ultrasound radiology in Europe and Asia.
Lars Leksell
Two other examples of Leksell's innovation deserve to be mentioned. He was the first to apply ultrasound in neurosurgical diagnosis by the development of echoencephalography as early as 1955. Moreover, his double action rongeur has become an indispensable tool in the hands of most neurosurgeons.