Medical ultrasound
A contrast medium for medical ultrasonography is a formulation of encapsulated gaseous microbubbles to increase echogenicity of blood, discovered by Dr Raymond Gramiak in 1968 and named contrast-enhanced ultrasound. This contrast medical imaging modality is clinically used throughout the world, in particular for echocardiography in the United States and for ultrasound radiology in Europe and Asia.
Ultrasonic toothbrush
Ultrasound has been used in Medicine for close to half a century and its safety has been studied for almost the same period of time. In 1992, the US FDA first allowed the use of ultrasound at a frequency of 1.6 MHz in a toothbrush. In 1993, the American Institute of Ultrasound in Medicine (AIUM), in conjunction with the National Electrical Manufacturers Association (NEMA) developed the Output Display Standard (ODS), including the thermal index and mechanical index which have been incorporated into the FDA’s new regulations. These regulations limit the power output of these devices to a level low enough to avoid raising surrounding tissue temperature by more than 1 °C.