2008 Orange Bowl
In the wake of the Hokies's defeat, Virginia Tech chose to start a new quarterback and a new offensive plan. Behind freshman Tyrod Taylor, the Hokies rolled to five straight victories, including a win over No. 22 Clemson by 18 points. During the winning streak, Sean Glennon, who had started at quarterback for the Hokies during the first two games of the season, returned to alternate possessions with Taylor in an unusual two-quarterback system. On October 25, the Hokies had a chance to make up for their early-season loss to LSU when they faced No. 2 Boston College on a Thursday night in Blacksburg, Virginia. Though the Hokies dominated for most of the game, Boston College quarterback Matt Ryan managed a late-game comeback to win the game 14–10 with 11 seconds remaining.
2008 Orange Bowl
After the Kansas kickoff, Virginia Tech took over at its 33-yard line. Needing a score, the Hokies committed a five-yard false start penalty before quarterback Sean Glennon was sacked by Kansas' Mike Rivera. The two plays pushed the Virginia Tech offense back, preventing them from gaining a first down. Forced to punt the ball away, Virginia Tech had to play defense as Kansas took over at its 28-yard line. Secure in their lead, Kansas elected to run the ball in an effort to keep the clock moving and bring the game to an end more quickly. Brandon McAnderson broke free for 28 yards on the first play of the drive, and Jake Sharp contributed another first down on the ground before the Hokie defense stopped Kansas on an attempt to earn a first down on a fourth-and-two deep inside Virginia Tech territory.