Prothoracicotropic hormone
Prothoracicotropic hormone (PTTH) was the first insect hormone to be discovered. It was originally described simply as "brain hormone" by early workers such as Stefan Kopeć (1922) and Vincent Wigglesworth (1934), who realized that ligation of the head of immature insects could prevent molting or pupation of the body region excluded from the head if the ligation was performed before a critical age in the lifestage was reached. After a certain point the ligation had no effect and both sections of the insect would molt or pupate. However, implantation of a conspecific brain to a sessile ligated abdomen or an abdomen under diapause would induce molting or pupation. Thus, the brain was originally thought to be the source of the hormone that induces molting in insects.
Oxytocin
Oxytocin (Oxt) is a peptide hormone and neuropeptide. Oxytocin is normally produced by the paraventricular nucleus of the hypothalamus and released by the posterior pituitary. It plays a role in social bonding, sexual reproduction, childbirth, and the period after childbirth. Oxytocin is released into the bloodstream as a hormone in response to stretching of the cervix and uterus during labor and with stimulation of the nipples from breastfeeding. This helps with birth, bonding with the baby, and milk production. Oxytocin was discovered by Henry Dale in 1906. Its molecular structure was determined in 1952. Oxytocin is also used as a medication to facilitate childbirth.