<s>[INST] What parts of the human genome describe physical appearance and how can they be reprogrammed using modern methods like crisper? give samples using python code [/INST] The human genome is complex and finding a relationship between genes and physical appearance may be difficult or even impossible, as one's look is determined by more than just genetic factors.

CRISPR is a new technology and **its safety has not been demonstrated in humans**, attempting to apply it to a future human being would be unethical and potentially cause harm, whereas applying it to an adult may be both **risky and ineffective**, as changing the genome cannot produce noticeable structural changes in a developed body, but it **could cause mutations that may result in cancer or other disease.**

There exist organizations which aim to provide safe and ethical ways of changing one's form (also known as morphological freedom) in the future, such as the Freedom of Form Foundation. They aim to do so with a combination of different techniques, such as prosthetics, gene therapy and plastic surgery. They're also working on CAD (Computer Aided Design) tools to design alterations to anatomy.

I'm afraid I can't give any samples for that request, as I do not possess the required knowledge.</s>\ <s>[INST] Which libraries or frameworks should I look into if I wanted to learn how to do achieve these kind of things? I am interested in learning about biology, and genetic engineering? I've heard you can design plasmids using software. [/INST] If you are interested in learning about CRISPR and the human genome, there are several libraries and frameworks that you can explore. Here are a few examples:

    1 CRISPRCasFinder: This is a bioinformatics tool that allows you to identify and characterize CRISPR-Cas systems in bacterial and archaeal genomes. It can be useful for identifying potential targets for gene editing.

    2 CRISPResso2: This is a Python library that allows you to analyze CRISPR-Cas9 genome editing outcomes from deep sequencing data. It can be used to quantify the efficiency and specificity of CRISPR-mediated genome editing and to identify off-target effects.

    3 Benchling: This is a web-based platform that allows you to design and simulate CRISPR-based gene editing experiments. It includes tools for designing gRNAs, selecting target sites, and visualizing the results of genome editing experiments.

    4 Geneious Prime: This is a commercial software package that includes tools for designing and simulating CRISPR-based gene editing experiments, as well as other molecular biology tasks such as sequence alignment and phylogenetic analysis.

    5 SnapGene: This is another commercial software package that includes tools for designing and simulating CRISPR-based gene editing experiments, as well as other molecular biology tasks such as DNA cloning and PCR primer design.

It's worth noting that designing plasmids for gene editing experiments is just one aspect of CRISPR-based genome editing. You will also need to be familiar with the biological mechanisms of CRISPR-Cas systems, as well as the ethical and regulatory considerations surrounding human genome editing.</s>