<s>[INST] What effect does turning on the Yamanka factors have in human cells? [/INST] Turning on the Yamanka factors in human cells has been found to modulate the expression of genes related to nutrient sensing and metabolism. This can lead to increased production of proteins that are involved in energy production, cellular growth, and repair. Additionally, it has been shown to increase the efficiency of energy production in mitochondria, which can lead to improved cell survival in stressful conditions.</s>\ <s>[INST] How are they involved with stem cells? [/INST] 