<a href="https://en.wikipedia.org/wiki/Great_New_York_City_Fire_of_1845" id="mwfw" rel="mw:WikiLink" title="Great New York City Fire of 1845">Great New York City Fire of 1845</a>: The last great fire to affect <a href="https://en.wikipedia.org/wiki/Manhattan" id="mwgA" rel="mw:WikiLink" title="Manhattan">Manhattan</a> begins early in the morning and is subdued that afternoon. The fire kills four firefighters and 26 civilians and destroys 345 buildings.