We proposed on-chip spatiotemporal fluorescence sensing for monitoring interactions between cells and environment. As a demonstration, Spatiotemporal variation of Calcium ion was measured and during transformation of octacalcium phosphate (OCP) to hydroxyl apatite (HA) in the microfluidic chip.
['Keisuke Takagi', 'Hisataka Maruyama', 'Taisuke Masuda', 'Osamu Suzuki', 'Fumihito Arai']
Multi fluorescence microsensors for spatiotemporal measurement of culture environment in a microfluidic chip