Background#R##N#Next Generation Sequencing (NGS) technology generates tens of millions of short reads for each DNA/RNA sample. A key step in NGS data analysis is the short read alignment of the generated sequences to a reference genome. Although storing alignment information in the Sequence Alignment/Map (SAM) or Binary SAM (BAM) format is now standard, biomedical researchers still have difficulty accessing this information.
['Guorong Xu', 'Nan Deng', 'Zhiyu Zhao', 'Thair Judeh', 'Erik K. Flemington', 'Dongxiao Zhu']
SAMMate: a GUI tool for processing short read alignments in SAM/BAM format