Background#R##N#An increasing number of genetic components are available in several depositories of such components to facilitate synthetic biology research, but picking out those that will allow a designed circuit to achieve the specified function still requires multiple cycles of testing. Here, we addressed this problem by developing a computational pipeline to mathematically simulate a gene circuit for a comprehensive range and combination of the kinetic parameters of the biological components that constitute the gene circuit.
['Austin W. T. Chiang', 'Ming-Jing Hwang']
A computational pipeline for identifying kinetic motifs to aid in the design and improvement of synthetic gene circuits