The following resources for comparative protein structure modeling and analysis are described (http://salilab.org): MODELLER, a program for comparative modeling by satisfaction of spatial restraints; MODWEB, a web server for automated comparative modeling that relies on PSI-BLAST, IMPALA and MODELLER; MODLOOP, a web server for automated loop modeling that relies on MODELLER; MOULDER, a CPU intensive protocol of MODWEB for building comparative models based on distant known structures; MODBASE, a comprehensive database of annotated comparative models for all sequences detectably related to a known structure; MODVIEW, a Netscape plugin for Linux that integrates viewing of multiple sequences and structures; and SNPWEB, a web server for structure-based prediction of the functional impact of a single amino acid substitution.
['Narayanan Eswar', 'Bino John', 'Nebojsa Mirkovic', 'Andras Fiser', 'Valentin A. Ilyin', 'Ursula Pieper', 'Ashley C. Stuart', 'Marc A. Marti-Renom', 'Mallur S. Madhusudhan', 'Bozidar Yerkovich', 'Andrej Sali']
Tools for comparative protein structure modeling and analysis.