Background#R##N#Results of phylogenetic analysis are often visualized as phylogenetic trees. Such a tree can typically only include up to a few hundred sequences. When more than a few thousand sequences are to be included, analyzing the phylogenetic relationships among them becomes a challenging task. The recent frequent outbreaks of influenza A viruses have resulted in the rapid accumulation of corresponding genome sequences. Currently, there are more than 7500 influenza A virus genomes in the database. There are no efficient ways of representing this huge data set as a whole, thus preventing a further understanding of the diversity of the influenza A virus genome.
['Jiajie Zhang', 'Amir Madany Mamlouk', 'Thomas Martinetz', 'Suhua Chang', 'Jing Wang', 'Rolf Hilgenfeld']
PhyloMap: an algorithm for visualizing relationships of large sequence data sets and its application to the influenza A virus genome