Embedding active sensing microelectronic substrates in microfluidic devices is a challenging feature in functional integration of complex bioanalytical protocols in lab-on-a-chip platforms. This paper reviews the design trade-offs of optical and impedance sensing techniques for cell biology imaging in view of their SNR limits. Results are discussed on the basis of experimental data of two prototypes.
['Aldo Romani', 'Roberto Guerrieri', 'Marco Tartagni', 'N. Manaresi', 'Gianni Medoro']
Beyond the microscope: embedded detectors for cell biology applications