Recent experiments in hippocampus show that a cholinergic drive can induce gammafrequency oscillations. At present, it is unclear what is the speci"c role of interneurons in producing these oscillations. Here we compare two possible mechanisms that can generate this type of rhythmogenesis in the hippocampus: (i) Recurrent excitatory, non-NMDA, coupling between pyramidal neurons in combination with fast feed-forward inhibition, versus (ii) pyramidal neurons stochastically entrained to the rhythm of interneurons that are synchronized by mutual inhibition. ( 2000 Elsevier Science B.V. All rights reserved.
['S. Zhang', 'Jorge V. José', 'Paul H. E. Tiesinga']
Model of carbachol-induced gamma-frequency oscillations in hippocampus ☆