Background#R##N#Scaffolding is an essential step in the genome assembly process. Current methods based on large fragment paired-end reads or long reads allow an increase in contiguity but often lack consistency in repetitive regions, resulting in fragmented assemblies. Here, we describe a novel tool to link assemblies to a genome map to aid complex genome reconstruction by detecting assembly errors and allowing scaffold ordering and anchoring.
['Mohammed-Amin Madoui', 'C. Dossat', 'Léo d’Agata', 'Jan van Oeveren', 'Edwin A. G. van der Vossen', 'Jean-Marc Aury']
MaGuS: a tool for quality assessment and scaffolding of genome assemblies with Whole Genome Profiling™ Data