Background#R##N#Proteomics of bacterial pathogens is a developing field exploring microbial physiology, gene expression and the complex interactions between bacteria and their hosts. One of the complications in proteomic approach is micro- and macro-heterogeneity of bacterial species, which makes it impossible to build a comprehensive database of bacterial genomes for identification, while most of the existing algorithms rely largely on genomic data.
['Dmitry S. Ischenko', 'Dmitry G. Alexeev', 'Egor A. Shitikov', 'Alexandra Kanygina', 'Maja V. Malakhova', 'Elena S. Kostryukova', 'Andrey K. Larin', 'Sergey Kovalchuk', 'Olga Pobeguts', 'Ivan Butenko', 'Nikolay A. Anikanov', 'Ilya A. Altukhov', 'Elena N. Ilina', 'Vadim M. Govorun']
Large scale analysis of amino acid substitutions in bacterial proteomics