Researchers use animal studies to better understand human diseases. In recent years, large-scale phenotype studies such as Phenoscape and EuroPhenome have been initiated to identify genetic causes of a species' phenome. Species-specific phenotype ontologies are required to capture and report about all findings and to automatically infer results relevant to human diseases. The integration of the different phenotype ontologies into a coherent framework is necessary to achieve interoperability for cross-species research.
['Anika Oellrich', 'Georgios V. Gkoutos', 'Robert Hoehndorf', 'Dietrich Rebholz-Schuhmann']
Quantitative comparison of mapping methods between Human and Mammalian Phenotype Ontology