Tumor growth induces angiogenesis that results in immature/dysfunctional vessels. The purpose of this study is to demonstrate feature extraction and analysis of tumor vascular structure based on non-fluorescent microscopic images for long-term investigation. The averages of angle, and radius of microvasculature on the surface of the tumor were measured and analyzed at different weeks for each tumor. In the t-test results, we report statistical analyses which confirm at different significance levels, radius have significant effects in growing a tumor's vascular network. No difference in average angle between parent vessel and children vessel by t-test was found.
['Wen-Chen Lin', 'Wen-Chi Lin', 'Cheng-Lun Tsai', 'Kang-Ping Lin']
Feature analysis and extraction of tumor vascular structure on microscopic images