article Head motion (HM) is a critical confounding factor in functional MRI. Here we investigate whether HM during resting state functional MRI (RS-fMRI) is influenced by genetic factors in a sample of 462 twins (65% female; 101 MZ (monozygotic) and 130 DZ (dizygotic) twin pairs; mean age: 21 (SD = 3.16), range 16-29). Heritability estimates for three HM components—mean translation (MT), maximum translation (MAXT) and mean rotation (MR)—rangedfrom 37 to51%.Wedetecteda significantcommon geneticinfluenceonHMvariability,with about two-thirds (genetic correlations range 0.76-1.00) of the variance shared betweenMR, MTand MAXT. A compos- ite metric (HM-PC1), which aggregated these three, was also moderately heritable (h 2
['B. Couvy-Duchesne', 'Gabriëlla A.M. Blokland', 'Ian B. Hickie', 'Paul M. Thompson', 'Nicholas G. Martin', 'Greig I. de Zubicaray', 'Katie L. McMahon', 'Margaret J. Wright']
Heritability of head motion during resting state functional MRI in 462 healthy twins.