Background#R##N#Repositioning approved drug and small molecules in novel therapeutic areas is of key interest to the pharmaceutical industry. A number of promising computational techniques have been developed to aid in repositioning, however, the majority of available methodologies require highly specific data inputs that preclude the use of many datasets and databases. There is a clear unmet need for a generalized methodology that enables the integration of multiple types of both gene expression data and database schema.
['Adam S. Brown', 'Sek Won Kong', 'Isaac S. Kohane', 'Chirag J. Patel']
ksRepo: a generalized platform for computational drug repositioning