text: Genotype SS AA AS AC Sickle Cells Heamoglobin Genotype Tests Genetic Constitution Blood Type Type A Type B Type AB Type O Blood Group Compatibility HB Electrophoresis Blood Disorder ABO/RH
  BloodtypeIn this blog post we will look at the definition of the words genotype and blood group and why it is important to know your genotype and your blood group compatibility. We will also look at the tests used to determine genotype and blood types and which tests are offered by Bridge Clinic.
  What is a Genotype?
  A genotype is the entire genetic constitution of an individual, i.e. the genetic makeup of an organism or group of organisms with reference to a single trait, set of traits, or an entire complex of traits. In a nutshell: your genotype is your complete heritable genetic identity; the sum total of genes transmitted from parent to offspring.
  There are four hemoglobin genotypes (hemoglobin pairs/formations) in humans: AA, AS, SS and AC (uncommon). SS and AC are the abnormal genotypes or the sickle cells. We all have a specific pair of these hemoglobin in our blood which we inherited from both parents.
  Why it’s Important to Know Your Genotype
  Knowing one's hemoglobin genotype before choosing a life partner is important because there may be compatibility issues which could have devastating effects when it comes to conception.
  Individuals with sickle cells experience severe pains in body parts where oxygen flow is compromised due to blockage in the blood vessels. Read about sickle cell disease here.
  Types of Hemoglobin Genotype Tests
  Newborn Screening | Diagnostic Testing | Carrier Testing | Prenatal Testing | Preimplantation Testing | Predictive and Presymptomatic Testing | Forensic testing
  What is a Blood Group and Type?
  To classify blood, antibodies and inherited antigenic substances on the surface are evaluated.
  There are four blood GROUPS:
  An Additional Marker in Blood: Rhesus factor
  This is simply a protein that may be present on the surface of red blood cells. Some people have it and others don’t. If you have it, your blood type is further classified as positive; if you don’t, your blood type is further classified as negative. It is just a genetic difference (e.g. blue VS green eyes) and nothing to worry about. Therefore present Rhesus factor = Positive. No Rhesus factor = Negative.
  Why it’s Important to Know Your Blood Group Compatibility
  It is important to know your blood type if you need a blood transfusion or if you want to donate blood. It also plays a role in determining paternity. Before a blood transfusion takes place it must be established that the donor’s blood type is compatible with the recipient’s blood type. The combination of certain antibodies (proteins protecting the body) can be harmful or even lead to fatal symptoms if antibodies perceive foreign cells as a threat. It is our immune systems’ way of protecting us.
  Types of Blood Test
  Complete Blood Count (CBC) | Blood Chemistry Tests | Blood Enzyme Tests | Blood Tests to Assess Heart Disease Risk.
  Tests Offered by Bridge Clinic
  1. HB ELECTROPHORESIS: Hemoglobin Electrophoresis Test (Code: HELEC P)
  Hemoglobin is a protein that transports oxygen. Hemoglobin abnormalities, caused by genetic mutations, can result in certain diseases or disorders. This test is therefore used to detect abnormal forms and/or relative amounts of hemoglobin.
  Why is this test done?
  Bridge Clinic as also offers PGD and PGS. Preimplantation genetic diagnosis (PGD) can be performed during in vitro fertilisation (IVF) to choose embryos without certain diseases/conditions. Additionally, some chromosomal abnormalities can be picked up during a preimplantation genetic screening (PGS).
  2. Blood Type Test: ABO/RH (Code 1125 P)
  During a blood type test, blood is tested for blood group antigens (ABO) and/or the Rh antigen. This test is done to:
  Get in touch to book a test or to find out more about your genotype and blood type.
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