[2+3] Amide Cages by Oxidation of [2+3] Imine Cages - Revisiting Molecular Hosts for Efficient Nitrate Binding [Data]
<|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully.  <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'The pollution of groundwater with nitrate is a serious issue because nitrate can cause several diseases such as methemoglobinemia or cancer. Therefore, selective removal of nitrate by efficient binding to supramolecular hosts is highly desired. Here we describe how to make [2+3] amide cages in very high to quantitative yields by applying an optimized Pinnick oxidation protocol for the conversion of corresponding imine cages. By NMR titration experiments of the eight different [2+3] amide cages with nitrate, chloride and hydrogen sulfate we identified one cage with an unprecedented high selectivity towards nitrate binding vs chloride (S = 446) or hydrogensulfate (S >13000). NMR experiments as well as single-crystal structure comparison of host-guest complexes gave insight into structure property relationships' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Amides","Anions","dynamic covalent chemistry","Noncovalent interactions","organic cage compounds"]} <|eot_id|>
 Here is the Description of a dataset. Description:'The pollution of groundwater with nitrate is a serious issue because nitrate can cause several diseases such as methemoglobinemia or cancer. Therefore, selective removal of nitrate by efficient binding to supramolecular hosts is highly desired. Here we describe how to make [2+3] amide cages in very high to quantitative yields by applying an optimized Pinnick oxidation protocol for the conversion of corresponding imine cages. By NMR titration experiments of the eight different [2+3] amide cages with nitrate, chloride and hydrogen sulfate we identified one cage with an unprecedented high selectivity towards nitrate binding vs chloride (S = 446) or hydrogensulfate (S >13000). NMR experiments as well as single-crystal structure comparison of host-guest complexes gave insight into structure property relationships' . Please return only a json list of at most 3 Keywords corresponding to the Description:.
The pollution of groundwater with nitrate is a serious issue because nitrate can cause several diseases such as methemoglobinemia or cancer. Therefore, selective removal of nitrate by efficient binding to supramolecular hosts is highly desired. Here we describe how to make [2+3] amide cages in very high to quantitative yields by applying an optimized Pinnick oxidation protocol for the conversion of corresponding imine cages. By NMR titration experiments of the eight different [2+3] amide cages with nitrate, chloride and hydrogen sulfate we identified one cage with an unprecedented high selectivity towards nitrate binding vs chloride (S = 446) or hydrogensulfate (S >13000). NMR experiments as well as single-crystal structure comparison of host-guest complexes gave insight into structure property relationships
Amides; Anions; dynamic covalent chemistry; Noncovalent interactions; organic cage compounds