Replication Data for: High resolution daily profiles of tissue adrenal steroids by portable automated collection
<|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully.  <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:' Rhythms are intrinsic to endocrine systems, and disruption of these hormone oscillations occurs at very early stages of disease. Since adrenal hormones are secreted with both circadian and ultradian periods, conventional single time point measures provide limited information about rhythmicity, and crucially do not provide information during sleep when many hormones fluctuate from nadir to peak concentrations. If blood sampling is attempted overnight, this necessitates admission to a clinical research unit, can be stressful and disturbs sleep. To overcome this problem, and to measure free hormones within their target tissues, we used microdialysis, an ambulatory fraction collector and liquid-chromatography tandem mass-spectrometry (LC-MS/MS) to obtain high-resolution profiles of tissue adrenal steroids over 24 hours in 214 healthy v' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Adrenal Cortex Function Tests","Adrenal Cortex Hormones","Adrenal Gland Diseases","Biomedical Technology","Circadian Rhythm","Hydroxycorticosteroids","Microdialysis","Monitoring, Ambulatory","Tandem Mass Spectrometry","Ultradian Rhythm"]} <|eot_id|>
 Here is the Description of a dataset. Description:' Rhythms are intrinsic to endocrine systems, and disruption of these hormone oscillations occurs at very early stages of disease. Since adrenal hormones are secreted with both circadian and ultradian periods, conventional single time point measures provide limited information about rhythmicity, and crucially do not provide information during sleep when many hormones fluctuate from nadir to peak concentrations. If blood sampling is attempted overnight, this necessitates admission to a clinical research unit, can be stressful and disturbs sleep. To overcome this problem, and to measure free hormones within their target tissues, we used microdialysis, an ambulatory fraction collector and liquid-chromatography tandem mass-spectrometry (LC-MS/MS) to obtain high-resolution profiles of tissue adrenal steroids over 24 hours in 214 healthy v' . Please return only a json list of at most 3 Keywords corresponding to the Description:.
 Rhythms are intrinsic to endocrine systems, and disruption of these hormone oscillations occurs at very early stages of disease. Since adrenal hormones are secreted with both circadian and ultradian periods, conventional single time point measures provide limited information about rhythmicity, and crucially do not provide information during sleep when many hormones fluctuate from nadir to peak concentrations. If blood sampling is attempted overnight, this necessitates admission to a clinical research unit, can be stressful and disturbs sleep. To overcome this problem, and to measure free hormones within their target tissues, we used microdialysis, an ambulatory fraction collector and liquid-chromatography tandem mass-spectrometry (LC-MS/MS) to obtain high-resolution profiles of tissue adrenal steroids over 24 hours in 214 healthy v
Adrenal Cortex Function Tests; Adrenal Cortex Hormones; Adrenal Gland Diseases; Biomedical Technology; Circadian Rhythm; Hydroxycorticosteroids; Microdialysis; Monitoring, Ambulatory; Tandem Mass Spectrometry; Ultradian Rhythm