Replication Data for: Biomarkers Discovery: The Benefit of the Study Exosomes Originated from Merkel Cell Carcinoma Cell Lines
<|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully.  <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Abstract: Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine type of skin cancer associated with a poor prognosis. This carcinoma named after its presumed cell of origin, the Merkel cell, a mechanoreceptor cell located in the basal epidermal layer of the skin. However, this notion has challenged by suggesting epidermal stem cells, fibroblasts or pro/pre-B cells as possible cells of origin. Merkel cell polyomavirus (MCPyV) is the only known polyomavirus directly linked to human cancer. Approximately 80% of all MCCs are positive for viral DNA. UV exposure is the predominant etiological factor for virus-negative MCCs. Immune therapy is a promising treatment for MCC patients, but it has failed to arrest the cancer progression.  Biomarkers discovery is an urgent, and high-throughput approaches were proposed. The high-dim' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Biomarkers discovery","Exosome","High-throughput approaches","Merkel cell carcinoma","Merkel cell polyomavirus"]} <|eot_id|>
 Here is the Description of a dataset. Description:'Abstract: Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine type of skin cancer associated with a poor prognosis. This carcinoma named after its presumed cell of origin, the Merkel cell, a mechanoreceptor cell located in the basal epidermal layer of the skin. However, this notion has challenged by suggesting epidermal stem cells, fibroblasts or pro/pre-B cells as possible cells of origin. Merkel cell polyomavirus (MCPyV) is the only known polyomavirus directly linked to human cancer. Approximately 80% of all MCCs are positive for viral DNA. UV exposure is the predominant etiological factor for virus-negative MCCs. Immune therapy is a promising treatment for MCC patients, but it has failed to arrest the cancer progression.  Biomarkers discovery is an urgent, and high-throughput approaches were proposed. The high-dim' . Please return only a json list of at most 3 Keywords corresponding to the Description:.
Abstract: Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine type of skin cancer associated with a poor prognosis. This carcinoma named after its presumed cell of origin, the Merkel cell, a mechanoreceptor cell located in the basal epidermal layer of the skin. However, this notion has challenged by suggesting epidermal stem cells, fibroblasts or pro/pre-B cells as possible cells of origin. Merkel cell polyomavirus (MCPyV) is the only known polyomavirus directly linked to human cancer. Approximately 80% of all MCCs are positive for viral DNA. UV exposure is the predominant etiological factor for virus-negative MCCs. Immune therapy is a promising treatment for MCC patients, but it has failed to arrest the cancer progression.  Biomarkers discovery is an urgent, and high-throughput approaches were proposed. The high-dim
Biomarkers discovery; Exosome; High-throughput approaches; Merkel cell carcinoma; Merkel cell polyomavirus