Supplementary material for the paper ‘Pappalysins and stanniocalcins and their relationship with the peripheral IGF axis in newborns and during development’
<|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully.  <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Background: Pappalysins (PAPP-A, PAPP-A2) modulate body growth byincreasing IGF-I bioavailability through cleavage of IGFBPs and areinhibited by stanniocalcins (STC1, STC2). Normative data of thesenovel factors, as well as of free IGF-I and uncleaved fractions ofIGFBPs are not well established.Objective: To determine serum concentrations of PAPP-A, PAPP-A2, STC1and STC2, in relationship with other GH-IGF axis parameters duringdevelopment.Patients and methods: Full-term newborns (150; gestational age: 39.30± 1.10 weeks), 40 preterm newborns (30.87 ± 3.35 weeks) and 1071healthy individuals (1-30 years old) were included in the study anddivided according to their Tanner stages (males and females): I:163males, 154 females; II:100 males, 75 females; III:83 males, 96females; IV: 77 males, 86 females; and V:109 ma' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Growth","IGFBP","IGF-I","normative data","pappalysin","stanniocalcin"]} <|eot_id|>
 Here is the Description of a dataset. Description:'Background: Pappalysins (PAPP-A, PAPP-A2) modulate body growth byincreasing IGF-I bioavailability through cleavage of IGFBPs and areinhibited by stanniocalcins (STC1, STC2). Normative data of thesenovel factors, as well as of free IGF-I and uncleaved fractions ofIGFBPs are not well established.Objective: To determine serum concentrations of PAPP-A, PAPP-A2, STC1and STC2, in relationship with other GH-IGF axis parameters duringdevelopment.Patients and methods: Full-term newborns (150; gestational age: 39.30± 1.10 weeks), 40 preterm newborns (30.87 ± 3.35 weeks) and 1071healthy individuals (1-30 years old) were included in the study anddivided according to their Tanner stages (males and females): I:163males, 154 females; II:100 males, 75 females; III:83 males, 96females; IV: 77 males, 86 females; and V:109 ma' . Please return only a json list of at most 3 Keywords corresponding to the Description:.
Background: Pappalysins (PAPP-A, PAPP-A2) modulate body growth byincreasing IGF-I bioavailability through cleavage of IGFBPs and areinhibited by stanniocalcins (STC1, STC2). Normative data of thesenovel factors, as well as of free IGF-I and uncleaved fractions ofIGFBPs are not well established.Objective: To determine serum concentrations of PAPP-A, PAPP-A2, STC1and STC2, in relationship with other GH-IGF axis parameters duringdevelopment.Patients and methods: Full-term newborns (150; gestational age: 39.30± 1.10 weeks), 40 preterm newborns (30.87 ± 3.35 weeks) and 1071healthy individuals (1-30 years old) were included in the study anddivided according to their Tanner stages (males and females): I:163males, 154 females; II:100 males, 75 females; III:83 males, 96females; IV: 77 males, 86 females; and V:109 ma
Growth; IGFBP; IGF-I; normative data; pappalysin; stanniocalcin