A potential effect of occupational exposures might be more pronounced among people who are likely to be occupationally active throughout the approximately 10-year period that passes between the baseline and follow-up examinations than it is among people who have fulfilled the requirements for old-age pension (65 years of age) or early retirement (60 years of age) at the time of the follow-up examination. It is therefore possible that this study is more relevant among participants who are younger than 50 years at baseline than it is among those who are 50 years or older. For this reason, we will perform a sensitivity analysis in which the sample is stratified by age at baseline (≥ vs <50 years). The outcome, statistical model, inclusion criteria, and covariates will otherwise be the same as they were in the primary prospective analysis.