Numerous studies have shown that β-catenin, a key downstream effector in the Wnt signalling pathway, is considered to be a cell-cell adhesion protein, and most likely promotes tumour progression once activated . We investigated the overexpression of β-catenin in vitro but without a change in vivo depending on our study, which prompted the speculation that β-catenin only acted as a biomarker of EMT but didn’t activate the β-catenin/wnt pathway.