Concerning the analysis of cognitive performance, measured by the MMSE, there was a negative correlation with BFI in both patient groups, mainly in the FTD group (p<0.001). This finding is in line with previous reports in the literature that have shown distinct types of cerebral changes predicting impaired performance on specific cognitive tests.35-37 Soderlund et al.35 also observed that subcortical atrophy estimated by means of ventricular enlargement were associated with cognitive deficits. Nevertheless, the measures used in the cited study were the BFI, the Caudate Ventricular Index and Occipital Ventricular Index. The average of the three indexes was used to calculate a global score. Furthermore, the 1254 participants had an MMSE score above 24 and were non-demented individuals.