7) Figure 3: it's unclear how the authors identified ct/ct embryos. Methods indicate that they did not raise homozygous adults, which then were incrossed. Rather it seems the experiments were done on individual embryos genotyped from an incross of ct/+ fish? Please clarify and make this also clear in the manuscript text. If the latter: an example of a genotyping PCR should be shown that can distinguish ct/+ from ct/ct embryos with and without Cre.