Historically, the diseases caused by some of these parasites have been classified as Neglected Tropical Diseases (NTDs) or Neglected Zoonotic Diseases (King, 2011) and were associated with the classical model of the ‘poverty trap’ covering tropical and sub-tropical regions in Africa, Latin America and the Indian subcontinent (Kuris, 2012). However, with global changes in climate and human demographics and associated practices, the classical models do not promise safe boundaries that might contain and/or stop the further global spread of many of these parasitic diseases (Colwell et al. 2011). The problems associated with these pathogens are further aggravated by the lack of effective vaccines (Dumonteil, 2007; Innes et al. 2011; McAllister, 2014; Black & Mansfield, 2016) and the paucity of reliable drugs (Zofou et al. 2014), in addition to the difficulties of vector or reservoir control (Colwell et al. 2011). Therefore, there is a recognized need to find new therapeutic targets in these causative agents in order to develop effective treatment regimens to avoid potentially catastrophic outbreaks, both in terms of human health and economic impact.