The hazards of aerosol particles were also studied. Zhang, Y. et al. showed that 73~80% of the particles were in exhaled aerosols, while 7~18% of the particles were stored in the alveoli. It is estimated that 20~27% of the particles entered the circulatory system, which is equivalent to the proportion for traditional cigarette smoke . Moreover, the size distribution and amount of particles of E-cigarettes are similar to those of traditional cigarettes, and some E-cigarettes produce more particles than traditional cigarettes. Particles may cause lung and systemic inflammation, and increase the risk of cardiovascular disease, respiratory disease and death .