“The GINS subunits of the CMG-Mcm10 complex ran off the gel, but a previous study demonstrated that Mcm10 preferentially associates with the entire CMG complex (Lõoke, et al., 2017). This is supported by densitometry analysis of gels showing GINS subunits in both the FLAG and MonoQ purified CMG-Mcm10 complexes (Figure 2—figure supplements 3 and 4).”