Figure S1. Measurement of telomere length by ImageJ and identification of cell types in TMA by H&E. Representative images of the telomere quantitative process, including the original, conversion, normalization, and gradually measurement, are shown. (A) Four images illustrate the intensity of DAPI signals stained for nuclear DNA (top panels) and the intensity of telomere signals in the same field of vision (bottom panels) in HCC cell lines. (B) Images indicate the DAPI signals stained for nuclear DNA (top panels) and matched telomere signals (bottom panels) in HCC tissues. (C) Representative H&E image staining of tumor cells, peritumor liver cells, NTFs, and CAFs (black arrow indicates fibroblasts). (D) Representative H&E images for illustrating PTILs, TILs, P‐BDECs, and T‐BDECs (original magnification ×40). NTFs = non‐tumoral fibroblasts; CAFs = carcinoma‐associated fibroblasts; PTILs = peritumor infiltrate lymphocytes; TILs = tumor infiltrating lymphocytes (arrowhead indicates lymphocyte); P‐BDECs = peritumor bile duct epithelial cells; T‐BDECs = tumor bile duct epithelial cells (black arrow indicates bile duct epithelial cells).