In our study, strong STHMN1 expression was identified in 26/30 (86.6%) of the patients while 4/30 (13.2%) of the cases had mild STMN1 expression; however, there was no difference in terms of response to treatment across these expression levels. Positive STHMN1 expression was observed in all of the tissue samples obtained from the patients in the present study. Hence, we considered that all tumor samples were the phosphorylated form of STHMN1; however we could not determine any relationship between STHMN1 expression and response to treatment. Eighteen (60%) of patients exhibited non response to TBR. A key role may be suggested for STHMN1 expression in the metastatic process as STHMN1 expression was observed in all of our patients, as seen in the literature.