We identified 853 publications of which 103 met our criteria for inclusion (Fig 1 and S1 File). 79 publications (77%) used mice and 24 (23%) used rats. 67 publications (65%) used male animals, 9 (9%) used females, 17 (16%) used mixed populations, and gender was not reported in 10 (10%) publications. At the initiation of treatment 43 animals (42%) were juvenile, 26 (25%) were adult, 10 (10%) were mature and age was not reported in 24 (23%) publications.