Further, we used nomogram to predict 2-year overall survival rate of individual patient in IHC. The results showed that age, T stage, N stage, M stage, and Oct4-EpCAM expression (p=0.040, HR=1.484, 95%CI 1.019-2.160) were included in the nomogram (Figure 9), indicating that Oct4-EpCAM double low expression group had better survival outcomes, which was similar to that of aforementioned multivariate analyses. The calibration curve of nomogram showed that the predictive probability of 2-year survival were very closely to the actual 2-year survival (Figure 10). Subsequently, we compared the predictive accuracy of prognosis between the nomograms based on Oct4-EpCAM expression and TNM staging (only T stage, N stage and M stage included, Figure 11, 12). The C-indexes of nomograms were 0.711 (95%CI 0.676-0.746), compared with 0.698 (95%CI 0.659-0.737) of TNM staging system in this study. The results indicated that the prognostic prediction accuracy of nomograms based on Oct4-EpCAM expression and other parameters was significantly better than TNM staging system alone (p=0.003).