We use the unique human Connectome scanner51 to acquire a dataset with gradients of up to 300mT/m, which is not readily available in most current MR machines. However, previous preclinical work by Dyrby et al.13 suggests that high diffusion gradients enrich the signal, which helps model fitting and comparison. Future challenges might be designed that focus on explaining the signal and estimating parameters from data more typical of clinical acquisitions.