DMS exerts cytoprotection against oxidative stress. (A) Cell viability in SH‐SY5Y cells after treatment with DMS for 12 h (n = 8). (B) The SH‐SY5Y cells were pretreated with or without DMS (6.25, 12.5, 25, 50, or 100 μm) for 30 min. After the incubation of H2O2 (150 μm for 12 h), the cell survival rate was measured with MTT test kit (n = 8, ## P < 0.01 vs. control, *P < 0.05, and **P < 0.01 vs. H2O2 group). (C) The SH‐SY5Y cells were pretreated with or without 12.5 μm DMS. After 12‐h incubation with or without 150 μm H2O2, cell viability was tested by trypan blue test (n = 7, ## P < 0.01 vs. control and ** P < 0.01 vs. H2O2 group). (D‐E) The SH‐SY5Y cells were pretreated with DMS (6.25, 12.5, 25, 50, or 100 μm) or Met (50, 100, 500, or 1000 μm) for 30 min. After the incubation of MPP (2 mm for 48 h), the cell survival rate was measured with MTT test kit (n = 8, ## P < 0.01 vs. control, *P < 0.05 and **P < 0.01 vs. MPP group).