KEGG annotation is the process of mapping genes of interest to the metabolic pathways. In our study, 1,863 DEGs were mapped to 243 KEGG pathways. The significantly changed pathways included ribosome (46 DEGs, ko03010), cytosolic DNA-sensing pathway (21 DEGs, ko04623), neuroactive ligand interaction (52 DEGs, ko04080), RNA polymerase (36 DEGs, ko03020), pancreatic secretion (34 DEGs, ko04972), ECM-receptor interaction (53 DEGs, ko04512), and cell adhesion molecules (25 DEGs, ko04514), all of which should be the key metabolic networks leading to cell proliferation, secretion, and signal transduction in AG.