To induce hypoxia/reoxygenation (H/R) injury, 2.5 × 104 cells/cm2 were plated in growth medium and incubated in a controlled humidified atmosphere at 37°C with constant 5% CO2 level. Sixteen hours after plating (time 0) hypoxic cultures were exposed to 3 hrs of hypoxia (1% O2) and then reoxygenated to 24 hrs. In OEC‐CM supplemented cell cultures the conditioned media was added at time 0 (Fig. 1A).