Dated phylogeny of Coptis inferred from the combined plastid and nuclear data using BEAST under the random clock model and birth-death tree prior. Gray bars represent 95% highest posterior density intervals. Nodes of interests were marked as 1–5 in bold. All nodes are strongly supported (PP > 0.95) except for one node (in dashed line). Plio., Pliocene; Plt., Pleistocene