Natural antioxidants have been considered to be promising protective agents against free radical mediated damage induced during cancer therapy. A number of effective compounds such as hoechst , cysteine , caffeine , calcium channel blockers , flavonoids , and 2-deoxy-D-glucose  have been identified. Natural antioxidants have also demonstrated effective protection against ROS mediated cellular damage during cancer chemotherapy and radiotherapy [20–22]. However, there are comparatively few investigations that investigate the use of natural protectors during chemotherapy and/or radiotherapy. The importance of such protectors is emerging due to frequent use of chemotherapeutics in combinational therapy with radiation, causing higher magnitude of toxicity than either of the above two modes of therapy.