The lead compounds from natural resources fail to enter into the market due to the poor pharmacokinetic properties. So, designing ligands satisfying the Adsorption, Distribution, Metabolism and Elimination (ADME) properties will go through the market as a good drug. The drugs should be orally absorbed and distributed to the site of action and eliminated from the body without leaving any traces, which produces adverse effects. Hence, the tools and computer-aided methods, nowadays, have become popular in identifying good drug candidate molecule [21, 22, 23].