Figure 2 shows the changes in the number of leukocytes, lymphocytes, intermediate cells (including monocyte, eosinophils, and basophils), and granulocytes numbers in the five groups after ETEC challenge. At 24 h after ETEC challenge, the lymphocyte concentrations decreased (P < 0.05) and the granulocyte concentrations increased (P < 0.05) in the ETEC group and Lactobacillus-supplemented groups relative to those in the CONT group. No significant difference (P > 0.05) was noted among the ETEC group and the Lactobacillus-supplemented groups. At 0, 24, and 144 h after ETEC challenge, the levels of leukocyte, lymphocyte, intermediate cell, and granulocyte did not change significantly (P > 0.05) in all groups.