Blood samples were taken by sterile venipuncture: Two mls of venous blood on EDTA containing tube were aspirated for CBC. Another two mls were aspirated on sodium citrate containing tube for prothrombin time and concentration by thrombrel-s (human thromboplastin containing calcium) from (Behring diagnostic Inc. USA). Five mls of venous blood were aspirated on a plain plastic tube and left to be clotted in the incubator and centrifuged to be separated for assessment of liver function tests (using Integra 400 auto analyzer). Hepatitis B surface antigen was measured by Enzyme Linked Immunosorbent Assay (Sanofi Diagnostic Pasture, Marne-La-Coquette. France).Hepatitis C antibody was measured by a third generation ELISA (BIOELISA HCV Kit, BIOKIT, S. A Barcelona). Blood urea and serum creatinine were measured (by fully automated clinical chemistry auto-analyzer system Konelab 20i.). A fresh stool sample was collected and stored at -20 °C for analysis for H. pylori stool antigen test (Premier Platinum HpSA, Meridian Diagnostics, Cincinnati, OH) [13, 14]. Abdominal Ultrasound: done using a real time equipment (Fukuda Denshi - 4500) linear machine. Upper endoscopy was done for patients only. Olympus pediatric gastroscope (GIFP3) was used for the procedure .