Preoperatively, patients with diabetes, stroke or heart disease had higher mRS scores than patients without these factors. Three months postoperatively, patients with stroke or heart disease were still significantly worse (higher mRS), while patients with diabetes were not. Postoperative improvement of the health condition according to physicians’ ratings did not differ between those with or without any of the four comorbidities (Table 5).Table 5mRS scores before and 3 months after surgery, along with physicians’ rating of postoperative relative to preoperative health condition in iNPH patients with comorbidities, compared to those without n (% within available scorings at specified time point)mRS, median (IQR) p Improved health condition, n (%) p WithWithoutWithWithoutPreoperative Hypertension350 (49.7)3 (2–3)2 (2–3).75––– Diabetes147 (21)3 (2–3)2 (2–3).019––– Stroke93 (13.3)3 (2–4)2 (2–3)< .001––– Heart disease171 (24.2)3 (2–3)2 (2–3).002–––3 months Hypertension331 (51.2)2 (1–3)2 (1–3).3666 (70)62 (80).16 Diabetes141 (21.8)2 (2–3)2 (1–3).08228 (68)101 (76).41 Stroke91 (14.2)3 (2–3)2 (1–3)< .00117 (77)111 (74).80 Heart disease161 (24.8)3 (2–3)2 (1–3).01325 (70)103 (75).52 mRS modified Rankin Scale