When studying the impact of morbidities on HRQoL, morbidities are usually considered separately . Most treatment plans and clinical guidelines target single diseases , but an effective intervention for one disease could be less effective or deleterious with the presence of coexisting conditions . Regarding associations between morbidities, patterns of morbidities can be established. However, few studies are identifying patterns and potential factors underlying such associations [16–20]. The interest of these patterns is to consider the interrelations or the cumulative effect between different morbidities. Methodological approaches that consider such patterns that are well-adapted to the respective study populations are needed, as is the need to understand the patterns of disease combinations and their complexity. The identification and standardization of patterns of multimorbidity might help in organizing specific treatment strategies and system-wide initiatives to improve the care of people with various types and degrees of multimorbidity. However, more evidence on multimorbidity patterns is required.