We analyzed the effects of PA-MSHA on the proliferation of pancreatic cancer and normal ductal epithelial cell lines using CCK-8 assays. PA-MSHA at concentrations of 0.125, 0.25, 0.5, 1.0, 2.0, 4.0, 8.0 × 109/mL inhibited the growth of PANC-1 and SW1990 pancreatic cancer cells in a time- and dose-dependent manner. In addition, treatment of HPDE6-C7 normal pancreatic ductal epithelial cells with PA-MSHA for 24 h and 48 h had little/no effect on proliferation (Figure 1). The IC50 values for the two pancreatic cancer cell lines were significantly higher than those of the normal pancreatic ductal epithelial cells (Table 1) (p < 0.05).