Glucose tolerance in male βVps13cKO mice. A–H: intraperitoneal glucose tolerance (1 g/kg body wt) was measured in Ctrl (solid black line) and KO (dashed line) male littermates fed either RC (A, C, E, G) or HFD (B, D, F, H). IPGTTs were conducted at 8 (A, B), 12 (C, D), 16 (E, F), and 20 (G, H) wk. Inset: AUC. Numbers of animals (n) for each experiment are given in AUC bars. *P < 0.05, **P < 0.01, 2-way ANOVA with Fisher's LSD post hoc test (main graphs) or unpaired Student's t-test (AUC, insets).