Clonorchiasis is a major endemic disease affecting over 35 million people in Asian countries including Korea, China, Thailand and Vietnam [1–3]. Clonorchis sinensis infections are caused by the ingestion of raw or undercooked freshwater fish that harbor the metacercariae . Complications associated with the infection increase with an increase in the intensity and duration of the infection. Clonorchis sinensis has also been recognized by the World Health Organization as a biological carcinogen that can induce cholangiocarcinoma in humans .