Telomere length in the TCGA cohort. (A) Telomere lengths in the entire cohort, n = 371, in subset 1 (matched tumor tissues and normal liver tissues, n = 53) and in subset 2 (matched tumor tissues and normal blood samples, n = 318). Numbers at the top and bottom show HCC cases with longer and shorter telomere lengths than paired normal, respectively. (B) Telomere length in matched tumor tissues and normal controls (n = 371). (C) Telomere length in matched tumor tissues and normal blood samples (n = 318). (D) Telomere length in matched tumor tissues and normal liver tissues (n = 53). (E) Kaplan–Meier curves of OS according to telomere length in the subset of 53 patients with tumor tissue/normal liver tissue. (F) Distribution of tumor telomere length according to the presence and absence of TERTp mutations (n = 371). (G) Kaplan–Meier curves of OS according to TERTp mutation status log‐rank test (comparing TERTp mut and TERTp wt). (A–D, F) Error bars indicate interquartile range. NT, normal tissue; TT, tumor tissue; NB, normal blood; mut, mutation; wt, wild type.