Solvent casting/salt leaching methods were used to fabricate PLGA porous scaffold. Sodium chloride particulates in the range of 355~400 μm particle size were used for control group and 500~600 μm for experimental group. Both groups were prepared by using a Teflon mold. Control specimens were prepared as 1.5 × 1.5 × 1.5 (cm3) in size and experimental specimens were prepared as 2 × 2 × 2 (cm3) and 2.2 × 2.2 × 2.2 (cm3) in size. In order to make same pore size after applying compression to the experimental specimens, the pore size was bigger for experimental specimen.