In the study presented here, we determined the ability of A. flavus to grow, spread, and accumulate aflatoxin in storage bags by placing non-contaminated grain in small satchels adjacent to A. flavus-contaminated grain contaminated with aflatoxin. We compared the Purdue Improved Crop Storage (PICS) hermetics bags with polypropylene woven bags. PICS bags are a triple layer hermetic storage bag that are effective at protecting stored grains from damaging insect infestation (Baoua et al., 2014, Murdock et al., 2012). Our results demonstrate the efficacy of PICS bags for protecting the grain from moisture and temperature fluctuations during storage.