We found 53.3% culture positivity in our case series, which is in accordance with previously reported rates between 44.4% and 66.7%. Park et al. suggested the importance of aqueous samples in isolating the microorganisms in endophthalmitis after vitrectomy. We found that aqueous was the most common intraocular sample obtained (52.4%) with a culture-positive yield similar to that of vitreous samples (33.3% vs. 35.0%), further validating its use.