Concluding, our extended cohort of paired Normal and PTC patients identified new DE lncRNAs and confirmed many other lncRNAs already reported. Additionally, to our knowledge, this is the first study to identify BRAFV600E-correlated lncRNAs in PTC, which will provide support for future studies aiming to identify BRAFV600E-linked events in attempt to optimize therapeutic treatment and diagnosis/prognosis of this aggressive PTC genotype.