Male New Zealand White rabbits (3.0 [0.2] Kg) were bred in the University of Burgundy animal facility (Dijon, France). Animal use and handling were approved by the local veterinary committee (i.e., Comité d’Ethique de l’Expérimentation Animale Grand Campus Dijon [C2EA– 105]), and were performed according to the European laws for animal experimentation in accordance with current recommendations mentioned in the Guide for the Care and Use of Laboratory Animals, National Institutes of Health No. 92–23, revised 1985. Animals were randomized into the SB or MV group within each experiment as follows: control uninfected (SB or MV, n = 5 in each), infected (SB+MRSA [n = 11] or MV+MRSA [n = 11]), statin pretreatment infected (SB+MRSA+Statin or MV+MRSA+Statin, n = 5 in each), LNZ-treated infected group (SB+MRSA+LNZ or MV+MRSA+LNZ, n = 5 in each) and the statin pretreatment LNZ-treated infected group (SB+MRSA+Statin+LNZ or MV+MRSA+Statin+LNZ, n = 5 in each).