The dynamics of infected RBCs are given by(2)dIdt=pR(t)M(t)−μI−pRt−αMt−αSwhere S indicates the proportion of infected RBCs surviving development, equal to e−μα when t>α and in the absence of drugs. An infected cell is generated when a merozoite invades an uninfected RBC and can be lost via two different routes. First, infected RBCs can die at a background rate μ. Second, infected RBCs burst to release merozoites after a period of α days (i.e., 1 day for the rodent malaria parasite, P. chabaudi). For simplicity, we omit immune responses that remove infected RBCs, although simulations of this model including a saturating immune response have delivered similar optimal conversion rate profiles (results not shown).