Genes differentially expressed in aged WT and CalpTG mice are related to inflammatory pathways. Heatmap representation of genes differentially expressed between old WT and CalpTG (TG) mice. Eighty-two renal-expressed transcripts have been found significantly differentially expressed between groups. Corresponding genes were represented using the Pheatmap R package, unsupervised clustering, Manhattan method (A, n = 6/group). Kegg and biocarta pathways found significantly enriched when comparing old WT and CalpTG mice (B). Pathways are immune related suggesting that large parts of difference observed are associated with inflammaging-related genes.