In this study, we aimed to better understand the relationship between the severity of cerebral subcortical atrophy and the type of dementia (FTD and AD), as well as to explore the relationship of age, duration and aggravation of dementia, educational level, daily living activities and cognition, with cerebral subcortical atrophy. Finally we test the usefulness of a linear measure of atrophy in differentiating AD from FTD.