(A) and (B) respectively show survival curves of high (green line) and low (blue line) ATM/MRE11 two-protein expression groups in lymph node (LN) negative and LN positive rectal cancers. These show the effect of LN status on the association between expression levels and disease-free survival (DFS). (C) and (D) respectively show overall survival (OS) and DFS survival curves of 54 patients who received preoperative radiotherapy in terms of high (green line) and low (blue line) two protein expression groups. Worse OS (P = 0.024) and DFS (P = 0.028) were seen with high expression.