The drug library was obtained from University of Rochester Pathway Discovery Resource (NCI Spectrum Compound Library containing 2400 chemical compounds, 1 mM for every compound). The -1.7-kb KLF2-luc promoter-driven luciferase reporter (KLF2-luc) plasmid, KLF2 -221bp promoter wild-type (WT) and KLF2 -221bp promoter mutant plasmids were gifted by Prof. Mukesh Jain21. KLF2 -221 plasmid contains MEF2 binding site while in KLF2 -221 mutant plasmid, the MEF2 binding site was mutated.