We assessed between-genotype variance heterogeneity for up to 1,927,671 directly genotyped or imputed SNPs (HapMap II CEU reference panel ) that passed quality control (QC). Meta-analyses of Levene’s test summary statistics  were performed for BMI (n≤44,211 participants), and blood concentrations of high-density lipoprotein cholesterol (HDL-C) (n≤34,315), low-density lipoprotein cholesterol (LDL-C) (n≤34,180), total cholesterol (TC) (n≤34,318) and triglycerides (TG) (n≤34,110). We then obtained marginal effects results for the same index traits and SNPs from publicly available GWAS summary data from the GIANT (Genetic Investigation of ANthropometric Traits) Consortium  and GLGC (Global Lipids Genetics Consortium) .