Survey findings highlighted the necessity of guidance for managing side effects, but clinical guidelines seemingly addressed this need. However, although serious adverse events and acute complications were mentioned, long-term and daily life affecting mild-to-moderate side-effects were usually lacking fields in the reviewed publications. This finding is in line with Basch et al. (Basch, 2016) stating that “chronic low-grade toxicities” are mostly ignored in current value frameworks. Nonetheless, initiatives to assign more importance to such mild-to moderate and daily life-affecting adverse events are on the horizon. ASCO—due to the high volume of comments received after having published their framework (Schnipper et al., 2015)—updated the original version and included also mild-to moderate adverse events in the updated framework.