Recently, decapping activator Dhh1 has been shown to promote decapping by slowing ribosome movement on mRNA (Sweet et al. 2012). Since Sbp1 was suggested to stimulate decapping activity of mRNAs with Dhh1 (Segal et al. 2006) and we also observed that Sbp1 interacts with polysomes (Fig. 8), a fascinating question to ask next is whether, similar to Dhh1, Sbp1 also targets an elongating ribosome to control the translation of mRNA. Further investigations will be needed to provide a complete picture of Sbp1-specific translational regulation.