To evaluate the effect of AHG on tumor cell elimination mediated by NK cells, the cytotoxicity of splenocytes against NK cells-sensitive YAC-1 lymphoma cells was investigated. As shown in Figure 2, compared with the NC group, the treatment with AHG (0.5–50 μg/mL) enhanced NK cells cytotoxicity significantly (p < 0.01). The maximum effective concentration was 5 μg/mL. The cytotoxicity of NK cells in AHG groups with the concentration ranged from 1 to 25 μg/mL were higher than that in LNT (40 μg/mL) group (p < 0.05). These results indicated that AHG strengthened the activity of NK cell against tumor cells.