The cost-effectiveness of GEC and Thyroseq® has also been an intense area of research. The cost for GEC and MTC is $4,875 while the cost for Afirma® MTC alone is $975 and that of Afirma® BRAF is $475 (Table 5). The cost of Thyroseq® V2 is $3200 (29). Despite these high costs, insured patient costs are capped at $300 for either GEC or ThyroSeq® V2. Numerous studies have reported on the cost-effectiveness of both GEC (90, 91) and Thyroseq® V2 (92).