The results of this study revealed that a laboratory triad of increased ALT levels (> 45 U/L), decreased albumin levels (< 4 g/dL) and negative H. pylori infection was a significant triad in predicting variceal bleeding as a cause in children presented with upper GIT bleeding as this triad was positive in 9 children, 8 of them (88.8%) were variceal bleeding in origin.