The SU.VI.MAX 2 participants were recruited through a postal campaign organized in 2007–2009 among all SU.VI.MAX participants. From the full initial SU.VI.MAX cohort (N = 13,017), 6,850 participants were agreed to participate in the SU.VI.MAX 2 study, and 5,925 participants were older than 55 years at enrollment and received a geriatric assessment . Sociodemographic characteristics data, morbidities data and quality of life data were available for 5,647 aged 55 years or older for inclusion in the present analyses (Fig 1).