Vavourakis et al.  proposed a BCS simulator that models the 3D post-surgical shape of the breast by coupling a physiological model of tissue recovery with a biomechanical model of pose estimation. The former predicts breast contraction caused by wound healing while the latter uses a Mooney-Rivlin biomechanical model of the breast to simulate deformations for different patient’s positions. The main stages of the surgery simulation (Figure 2) comprise the construction of a patient-specific Finite Element Model (FEM) of the breast, the definition of the tumor and the wound healing simulation itself, which uses the multiscale biomechanical model of wound healing described above.