The most challenging BSRTC diagnostic categories for the clinician to manage are the three indeterminate categories (AUS/FLUS, sFN and sM). Due to an associated low cancer risk, it is the AUS/FLUS diagnostic group that is especially difficult to manage. Despite the recommendations that AUS/FLUS be used as a ‘last resort’ diagnostic category, and that it should represent no greater than 7% of all BSRTC diagnoses at a particular institution , there is considerable variability in its utilization at different centers, with reporting rates that range from 0.8% to 27.12% . Several studies have also reported a higher ROM for the AUS/FLUS diagnostic category than has been previously suggested [3, 7]. In the current ATA guidelines, for thyroid nodules diagnosed as AUS/FLUS, in addition to a repeat FNAB, a multidisciplinary approach that combines clinical, sonographic and molecular characteristics, is now recommended . While many of the variables that are taken into account to assist with making clinical decisions are subjected to confounding influences, patient variables such as age and gender remain consistent.