One of the cardinal features of ageing is brain ageing, manifest in a wide spectrum of behavioural deficits including anxiety and impaired cognitive function. Changes in brain structural connectivity, decrease in neurogenesis, lipids peroxidation, oxidative stress, mitochondrial dysfunction, decline in neurotransmitters levels and beta amyloid (Aβ) overproduction have all been suggested to be major mediators of brain ageing and age-related neurologic disorders [3–5].