In medicine, whether in clinical or research settings, there are high levels of ethical requirements that are expected to be met. Respecting trial participants’ autonomy by providing them adequate amount of information is one of those requisites for ethical practice in medical research, and often, the PIL is presented to the participants as a tool to meet the requirements. The main purpose of the PIL, in this sense, would be to help participants voluntarily make a well-informed decision on the introduced matter. When the control intervention of the trial involves a placebo, there has to be even more cautious approach and full disclosure of such information [1, 24, 25]. On the other hand, there are concerns on too much information may disadvantage the participants, as in increasing a nocebo effect [26, 27], or resulting in a lengthy document that rather compromises participants’ understanding . Some argue that PILs are not in a reader friendly language , nor come with decision making aids . Therefore, for a PIL to fully serve its purpose, it seems necessary to inform the participants in a way that is not only being clear about what is going to happen, but also being considerate of how it actually helps them to make an informed decision.