A number of parasitic protozoal proteins have been identified as potential targets for antiparasitic chemotherapy . In conjunction with this review, we have examined the potential parasitic targets of Copaifera diterpenoids using molecular docking. It is currently not known what biomolecular targets from Leishmania or Trypanosoma may be responsible for the antiprotozoal activities of copaiba. The Copaifera diterpenoids (Figure 1, Figure 2 and Figure 3) were screened, in silico, against Leishmania drug targets  and Trypanosoma cruzi protein targets  using Molegro Virtual Docker v. 6.0.1 as previously described . The docking energies are summarized in Table 4 and Table 5.