3) Subsection “Epicardium-specific shha deletion during zebrafish heart regeneration”, end of first paragraph. Authors should show the expression pattern of shha during heart development and regeneration to rule out or confirm the possibility that non-epicardium-derived shha is present. Importantly, other broad drivers should be used to generate conditional knockout to see if stronger phenotypes can be detected during heart regeneration. If redundant Hh proteins are present, what are they? Where are they being expressed? How do you confirm weak phenotype are caused by redundancy but not because authors did not find the right one?