Conception of work: PB and PP; design of work: PB and PP; drafting of manuscript: PB, MD, ST, and AB; critical revision of manuscript: PB and PP; final approval of work: PB, MD, ST, AB, and PP; agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved: PB, MD, ST, AB, and PP.