The BPR demonstrated a remarkable sensitivity to synapse location that caused the modulation of pause length. Therefore, the geometrical arrangement of input patterns could be important to shape BPR (Bower, 2010; Abrams and Zhang, 2011; Wilms and Häusser, 2015; Valera et al., 2016), e.g., by differentiating responses to aa and pf synapses (Bower, 2002) or by exploiting prewired connections from granule cell clusters (Valera et al., 2016).