Autophagy plays important function in regulating cell homeostasis. Autophagy performs homeostatic ‘quality control’ functions to eliminate unfolded proteins or damaged organelles. Under conditions of high cellular stress, such as during nutrient starvation, bulk autophagy is induced to degrade intracellular components for recycling and building blocks necessary for cell survival.1 Dysfunction of autophagy machinery often results in a variety of human diseases, such as cancer.2, 3, 4, 5