A collection of formalin-fixed, paraffin-embedded human HB (n = 28) samples was used in the present study. The clinicopathological features of liver cancer patients are summarized in Table 2. HB specimens were collected at the Medical University of Greifswald (Greifswald, Germany) and from the Archives of the Pathology Departments of Semmelweis University (Budapest, Hungary). Institutional Review Board approval was obtained at the local Ethical Committee of the Medical University of Greifswald and the Regional Ethical Committee of the Semmelweis University. Informed consent was obtained from all subjects.