Cartilage specimens were tested using indentation compression using a Mach-1 material testing machine (Biomomentum, Canada). Each specimen was loaded to 300 g at 1 mm/sec via a 1 kg load cell. The Young’s modulus was reported for native tissue as well as the end points for protocol A at day 35, protocol B and C at day 14 with N = 3 at each time point. In addition, the percentage weight reduction in comparison to native for the different protocols was recorded.