The segmented nature of the genome of influenza viruses is responsible for its ability to reassort its eight RNA genes when cells are co-infected with two different influenza virus strains1. Influenza A virus of swine origin (IAV-S) circulating in pigs have been known to occasionally reassort with avian and human influenza viruses to generate novel genotypes and establish new swine influenza virus lineages. Importantly, these new lineages might represent influenza pandemic threats for humans, as highlighted by the last 2009 H1N1 influenza virus pandemic2. Despite several introductions of avian influenza virus genes into swine strains by reassortment, only viruses from H1, H2, and H3 subtypes out of the 16 possible avian influenza virus subtypes have been known to circulate in pigs in the last century, mirroring the same subtypes that have been known to circulate in humans.