To our knowledge, this is the first study to evaluate the time from symptom onset to presentation at clinic (extrahospital pathway) for patients with nvAMD in the UK. There are, however, several limitations to the study. First, assessment of presentation delay might be difficult due to the retrospective nature of evaluation of symptom onset by patients. Second, the perception of symptoms is also highly subjective, often depending on factors such as existing cognitive function, ocular dominance of the affected eye and baseline visual acuity of the unaffected eye. Nevertheless, it is noteworthy that this time interval often varies widely between patients and is prolonged in most cases. Therefore, although less accurate than formal angiographic diagnosis, we thought it is important to investigate this time interval as it would be accessible to intervention.