Our findings suggest transmission of MERS-CoV has occurred among camels in Bangladesh, extending the previously reported range of this virus (up to ≈1,900 km east of Pakistan). Exactly where or when imported camels became infected is unclear. To date, no human cases of MERS-CoV have been reported in South Asia. The possibility of having MERS-CoV–infected camels in Dhaka, a populous city with ≈18 million persons, presents a potential risk for human outbreaks. Insufficient surveillance, behavioral differences in human–camel interactions compared with Middle Eastern societies, or differences in virus strains or human susceptibility might explain the lack of observed cases. Improved surveillance of camels along camel trade routes, camel herds in Dhaka, and persons who have close contact with camels will help assess the transboundary movement and the risk for zoonotic transmission in Bangladesh. Given the ubiquity of MERS-CoV in dromedary camels, the predictable seasonal movement of camels into Dhaka, and a higher incidence of infection in persons with frequent contact with camels (10), targeted public health messaging that promotes handwashing after contact with camels and avoidance of exposure to camel excreta might help reduce the risk for zoonotic MERS-CoV transmission.