In females, oogenesis is initiated during early embryonic development but remains in a state of arrest until ovulation. Conversely in males, spermatogenesis occurs continuously following the first wave at puberty. As such, differences in recombination may reflect structural or epigenetic differences in the genome at the time of crossover formation. Given PRDM9's role as an H3 K4 trimethyltransferase, we investigated the association of H3K4me3 peaks with male and female recombination. Since data are currently lacking for oocytes, we focused on a testis sample22.