In the Z− model, a 10-pulses/500 Hz pf burst generated a PC burst like in the Z+ model type I and type II responses. However, the Z− model was almost unable to generate any pauses, in either type I, II or III responses. This difference with the Z+ model was reduced by raising synaptic inhibition from 25 to 100 molecular layer interneuron synapses, which allowed pauses to emerge in the type I and type II responses (see Figure 2C). Therefore, the Z− PC model showed reduced ability to generate intrinsic BPR, in which the pauses were markedly dependent on the amount of molecular layer interneuron inhibition. It should be noted that the reduced ability of Z− PC models to generate intrinsic BPRs was likely to be related to the high basal firing rate, since Z− became similar to Z+ BPR when the basal firing rate was equalized with somatic injection of a constant negative current (Figure 2B).