Alginate is considered a very promising polysaccharide polymer that can be isolated from renewable sources such as brown algae or microorganisms. with applications in water treatment, an efficient alternative source for non-biodegradable plastic packaging materials and has many potential biotechnological applications since it is nontoxic, biocompatible, bioerodible and has a relatively low-cost in comparison with other polymeric materials. Sodium alginate can form hydrogels in the presence of divalent cations such as Ca2+ due to ionic cross-linking, owing to their chelation with the carboxyl groups. Crosslinked alginate chains form a buckled structure in the shape of an “egg box” whose cavity can accommodate divalent cations in the gelation process of water soluble sodium alginate. However, alginates possess poor mechanical properties, which restrict their widespread use in many biomedical and industrial applications. Hence, reinforcement of alginates via the incorporation of graphene oxide (GO) is promising with significant improvements reported using films of sodium alginate  and fibers of calcium alginate . More recently, GO-alginate composite hydrogels synthesised by the direct mixing method  using high amounts of calcium chloride have exhibited great enhancement of compression performance and water diffusion with the addition of even a minuscule amount of graphene oxide. This improvement of water diffusion is also very desirable in many biomedical applications due to mass transport plays an important role in cell survival .