In conclusion, new case-based disability weights have been estimated for individual injury-related ICD-10 diagnosis codes and commonly used injury groups. In general, these weights were higher than the corresponding largely panel-based weights that have been estimated previously. Long-term disability was evident in all categories of injuries admitted to hospital. The findings indicate that injury is often a chronic disorder and burden of disease estimates should reflect this. The impact of applying the new disability weights to DALY calculations will depend on the injury incidence profile of the population studied. A similar case-based approach could be used to determine disability weights for other conditions.