The study coordinators were invited to retrospectively review the results of all ophthalmological examinations in order to categorize ocular involvement as proven, probable, or possible Candida chorioretinitis or endophthalmitis . To be considered proven, ocular candidiasis had to be diagnosed based on the presence of an ocular lesion and on isolation of the microorganism from the vitreous humor by culture or histopathology-based identification. Probable Candida endophthalmitis consisted of vitritis or fluffy lesions with extension into the vitreous humor. Probable Candida chorioretinitis included deep focal white infiltrates in the retina, hemorrhages, Roth spots, or cotton wool spots. In patients with diabetes, hypertension, or concomitant bacteremia, ocular involvement was classified as possible based on previous criteria . Injection of intravitreal antifungal agents or intravitreal corticosteroids was recorded, as was the need for vitrectomy.