The overall rate of IVC filter insertion in the study was 16%. The frequency of IVC filter placement was 40% in the major bleeding group compared with 13% in the group without major bleeding (p=0.02), and 83% of these filters were placed because of discontinuation of anticoagulation due to major bleeding. IVC filter insertion was performed in 7.4% of patients at the end of an ultrasound-facilitated, catheter-directed, low-dose fibrinolytic procedure through the same sheath and in 8.7% of patients at a later point during the hospitalization as a separate procedure.