Severity of the infection and Pitt bacteremia score were recorded on the day of blood culture sampling . Proven catheter-related candidemia was defined according to current guidelines , whereas secondary candidemias required the microbiological documentation of the same Candida species at the origin of infection . When there was no apparent infection at another site, candidemia was classified as primary. An episode of candidemia was defined as persistent when patients had positive follow-up blood cultures performed according to IDSA guidelines .