An F-test was then performed to test the null hypothesis, H 0: β 0=β 1=β 4=β 24, against the alternate hypothesis, H 1: ∃t 1,t 2 such as \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$\beta _{t_{1}} \neq \beta _{t_{2}}$\end{document}βt1≠βt2. Multiple testing was handled by applying a BH approach (FDR <0.05). Probes for which the test was significant were probes for which the effect of L/G varied over time. In the sequel, this list of genes will be referred to as (List2).