Statistical analyses were done using GraphPad Prism version 6.05 (GraphPad Software Inc., La Jolla, CA, USA). Data were assumed to be normally distributed and confirmed by visual inspection of qq-plots. In case of severe deviations from normality, statistical analyses were performed on log-transformed data (natural logarithm) or with the use of non-parametric tests. Data are presented as mean ± SEM, except for log-transformed data, which are presented as geometric means with 95% confidence intervals. Differences in means between diet groups for each parameter were analyzed using one-way ANOVA, repeated measures two-way ANOVA or Kruskal–Wallis tests where appropriate, and compared after 16 weeks on the diets. Bonferroni or Dunn corrections, respectively, were used to adjust for multiple comparisons. Outliers in data sets were identified and removed using the ROUT-function in GraphPad Prism. p-values < 0.05 were considered significant.