Compared with the HLA-B allele, HLA-A∗02:07 was present in 33.3% of LTG-induced CADR patients and showed significantly higher frequencies than both the treatment control and general population groups with OR = 7.83, 95% CI = 1.60–38.25, P-value = 0.013 and OR = 3.27, 95% CI = 1.07–9.96, P-value = 0.029, respectively; in addition, HLA-A∗33:03 also had a significantly higher frequency than in the general population (OR = 3.16, 95% CI = 1.11–8.98, P-value = 0.023). Moreover, we found a significant association of LTG-induced MPE with HLA-A∗33:03 compared with the tolerant controls group (OR = 8.27, 95% CI = 1.83–37.41, P-value = 0.005) and general population group (OR = 8.43, 95% CI = 2.13–33.34, P-value = 0.002) as shown in Table 4.