This investigation was made possible by the use of an advanced model of the PC (Masoli et al., 2015), which was developed from earlier ones (De Schutter and Bower, 1994a,b; Rapp et al., 1994; Roth and Häusser, 2001; Steuber et al., 2007; Masoli et al., 2015) by including novel electrophysiological features and was validated against a large set of recent experimental data. The model was implemented with ionotropic synapses coming from granule cells (both aa and parallel fibers) and SCs. Additional synaptic mechanisms that may affect the response to specific input patterns (e.g., see Barbour et al., 1994; Takahashi et al., 1995; Tabata et al., 2005; Blot and Barbour, 2014) remain to be assessed.