(A) Validation by immunoblotting of AGO-2 immunoprecipitation (IP) performed on human PF samples using AGO-2 antibody. Mouse non-specific IgG antibody was used as control for the IP. ECs were used as positive control (CTRL). (B) The miRNA expression after AGO-2 IP is presented as fold enrichment relative to IgG; mean + SEM; n = 5. (C) AGO-2 in exosomes enriched from PF samples (representative western blot images). (D) AGO-2 IP was performed on exosomes enriched from PF samples. miRNA expression is expressed as fold enrichment in the AGO-2 IP relative to IgG; mean + SEM; n = 2. (E) Representative western blot images of DICER protein incorporated in the exosomes.