However, studies on the levels of IL-10, MMP-7 and MMP-9 in the serum are still limited and controversial. Owing to that, this study was conducted with the objective to find the differences between the serum levels of IL-10, MMP-7 and MMP-9 in patients with positive and negative H. pylori, and to analyse the correlations between the serum levels and the degree of gastritis based on histopathology appearance.