Our weights were also calculated using data from adult cases only. While the GBD studies do cover all age groups, the vignettes used in these studies have not accounted for differences between children and adults and the GBD weights have simply been assumed to be applicable to all ages. It is plausible that there are differences in the recovery trajectories of children and adults, although the magnitude of these differences is not yet known. Like the GBD 2013 weights, our new weights do not explicitly consider the presence of comorbidity. However, the new weights are calculated from responses to a multi-attribute utility instrument that included age-specific population preferences – and age is a partial proxy for comorbidity.