As shown in Figure 2, even without antigenic in vitro stimulation, we observed low, but detectable, frequencies of IFNγ+ (0.1–1.6%, minimum to maximum), TNF+ (0.06–1.3%) and IL2+ (0.3–1.8%) producing T cells from acute patients and in healthy DENV‐exposed donors’ T cells (IFNγ, 0.1–0.6%; TNF, 0.1–0.7%; IL2, 0.5–4.9%).