Advances in technology are inevitable, and will ultimately be the future of higher-resolution product understanding. The pre-competitive nature of NISTmAb RM 8671 makes it a useful, open-innovation platform to demonstrate novel analytical and biophysical technologies and/or competencies within an organization. It affords a common platform for discussion, harmonization and advancement of analytical and biophysical technologies as may be achieved through inter-laboratory comparisons. The presence of a widely available industry quality material, analyzed by countless permutations of every analytical tool available, will produce the most expansive and dynamic single protein characterization dataset to date. Continued operation in the pre-competitive space offers an unprecedented opportunity to harness these big data for developing foundational tools such as complex inter-method data integration, modeling, and data visualization to guide next-generation biopharmaceutical development.