Our study showed that telmisartan reduced microalbuminuria, not only pre-operatively, but also after open-heart surgery. The return to baseline levels was also faster than in group N-T. Angiotensin receptor blocking agents decrease some of the postoperative acute inflammatory agents in on-pump CABG patients with diabetes mellitus by lessening the systemic consequences of renal dysfunction, and may have additional cardiovascular effects by exerting beneficial effects on endothelial tissue elsewhere in the body and within the heart in this patients group. The cardiovascular benefits of angiotensin receptor antagonists have been evaluated, not only in terms of their ability to lower blood pressure, but also on their ability to prevent strokes, cardiac events and target-organ damage.14,16