Swiss Albino strain showed the largest (9.10 SMD, 95% CI, -8.39 to 26.61) and Albino the smallest (1.04 SMD, 95% CI, -2.28 to 0.19, χ2 for difference = 283.09, Τ2 = 1.73, I2 = 78.8%, d.f. = 60, p<0.0005; Fig 4C) change in SOD level. The administration duration of 60–112 days had the highest (3.23 SMD, 95% CI, 2.39 to 4.07) and 7–40 days the lowest (1.49 SMD, 95% CI, 0.20 to 2.78, χ2 for difference = 283.09, Τ2 = 1.73, I2 = 78.8%, d.f. = 60, p<0.0005; Fig 4D) impact on the fold of decrease in SOD level.