The common chemical structure as shown in Fig. 1 was utilized for development of GQSAR model. The molecules in the data set were fragmented in six different fragments (R-R6). The fragmented molecules were incorporated into the QSAR module of V life MDS for calculation of molecular descriptors. Molecular descriptors are nothing but the numerical values which represents physical and chemical information of the molecules. In GQSAR studies descriptors are representation of the physical and chemical behavior of substituents present.Fig. 1Molecular Template Utilized for Fragmentation pattern.Fig. 1