For the first direct comparison, two performance indicators F1-score (test set) and MCC (test set) should be given for each model. However, both evaluation metrics are not directly reported in the works of Wiener et al. and Huang et al. thus F1-score (test set) and MCC (test set) are indirectly derived from their works. To vividly demonstrate the performance of each model, the scatter plot of MCC (test set) vs. F1-score (test set) is plotted in Figure 3 based on Table 1 and Table S2.