This review surveys AHO research with an emphasis on the entire conventional outflow pathway, trabecular and post-trabecular. Research will be roughly organized into balancing the study of AHO structure (anatomy) and function (physiology of fluid flow) (Table 2). Glaucoma clinicians are already accustomed to structural (optical coherence tomography) and functional (visual field) relationships in the posterior segment. Our goal is to delineate the relationship between structure and function for the anterior segment as well.