Long noncoding RNAs are arising as key participants in cancer establishment and progression by several oncogenic mechanisms30, 32. On the other hand, it is of urge interest the determination of how these lncRNAs are activated and how they can be associated with specific events or genotypes, such as point mutations. BRAFV600E is the driver oncogenic mechanism with the greatest incidence in PTC7 and, therefore, any event correlated with this mutation will be necessary to understand BRAFV600E-induced aggressiveness.