Our organization, the Center for Global Health at the Colorado School of Public Health, has partnered with a local agricultural company, AgroAmerica, in the coastal lowlands of southwest Guatemala to create a health center and community health program that improve general health and access to healthcare to several small communities that make up a rural population of approximately 30,000 people (21). This area in Guatemala is cultivated with crops for export, primarily bananas and palm oil, owned by large agro-business enterprises, and the rural population struggles with poverty and lack of access to health, education, and reliable clean water. Our partnership is a unique relationship between a university, a private business, and a community. The program is largely funded by the Guatemalan agricultural company with our university establishing and supporting medical services through a Guatemalan-staffed clinic, laboratory, and pharmacy as well as community-based health programs for maternal and early childhood health. The CHNs in our program conduct home and group visits for pregnant women and children up to 3 years of age. They follow women throughout pregnancy, monitoring expectant mothers and providing interventions that improve prenatal care and delivery. Once the baby is born, the mother and child transition to an early childhood health and development segment of the program that combines a series of neonatal home visits, community education sessions, and mother–child interactive group visits to enhance the health and development of children from birth to 3 years of age. CHNs travel throughout the communities performing assessments of general health, child development and anthropometrics, and providing anticipatory guidance and basic health advice.