BACE1-AS can bind to BACE1 mRNA, increase the stability of the latter, and promote the synthesis of BACE1 protein, further increasing the production of cell Aβ. miRNA miR-485-5p has an inhibitory effect on BACE1 expression, whereas miRNA miR-485-5p and BACE1-AS have the same binding sites on BACE1 mRNA, so their regulation of BACE1 mRNA expression is antagonistic. BC1 induces APP mRNA translation via association with FMRP. Under inflammatory stimulation, lncRNA-17A can direct GPR51 splicing to produce GABAB receptor isoform variant B, thus causing the synthesis of a non-functional GABAB receptor. In addition, overexpression of 17A causes overproduction of Aβ.