Diseases are the result of an alteration at the bio-psycho-social level that can indicate lifestyle changes that should be made in addition to appropriate medical management and treatment. Emotions and stress significantly affect health and one’s susceptibility to a pathology, as well as one’s ability to recover from an illness. Psychoneuroimmunology should provide knowledge about the biological dynamics of conventional and alternative medicines for fighting disease. The psychoneuroimmunological axis comprises several disease-producing mechanisms in which different disciplines of medicine interact, implying the need for an integrative approach. The science of psychoneuroimmunology must go hand in hand with health education and the promotion of healthy lifestyles in order to attain patient health.