In this study, the serum levels of IL-10 increased significantly in positive H. pylori compared to negative H. pylori patients. This result was similar to that reported by Dlugovittzky et al, where the IL-10 serum levels of the positive H. pylori subjects were higher compared to negative H. pylori subjects (p<0.01) . However, other studies reported different conclusions, In the studies performed by Russo et al and Bayraktaroglu et al, they reported that there were no significant correlations between the positive H. pylori subjects and negative subjects, which might be caused by inhibition of further inflammation [17, 18].