NSTEMI non-ST-segment elevation myocardial infarction, STEMI ST-segment elevation myocardial infarction, UAP unstable angina pectoris, MI myocardial infarction; CABG coronary artery bypass graft, TLR target lesion revascularization, Ccr creatinine clearance, WF warfarin, DOAC direct oral anti-coagulant, NSAIDs non-steroidal anti-inflammatory drugs, PPIs proton pump inhibitors, PCI percutaneous coronary intervention