Copaifera oleoresins and diterpene acids have also shown antitrypanosomal activities. C. duckei and C. reticulata resins showed in vitro activity against T. evansi trypomastigotes . The diterpene acids—agathic acid, copalic acid, alepterolic acid, kaurenoic acid, methyl copalate, pinifolic acid, and ent-polyalthic acid—all showed antitrypanosomal activity against T. cruzi, including in the epimastigote, trypomastigote, and amastigote forms of the protozoan .