Treatment status of prasugrel and discontinuations are shown in Fig. 2. An initial LD was administered to 95.1% of patients. In the majority of patients, the LD was given before the initial PCI. In 99.0% of patients, the initial prasugrel LD was 20 mg. One out of 690 (0.1%) patients was given an MD of 2.5 mg/day; the remaining patients received an MD of 3.75 mg once-daily.Fig. 2 a Timing of loading, loading dose (LD), and starting maintenance dose (MD); b duration of prasugrel treatment and reasons for discontinuation. PCI percutaneous coronary intervention, CABG coronary artery bypass grafting