Thyroid cancer is more commonly diagnosed in younger people and in women . Unlike most other human cancer types, age represents an important disease prognosticator for individuals diagnosed with differentiated thyroid cancer (DTC). In the latest American Joint Commission on Cancer (AJCC) thyroid cancer staging system , cancer in patients 55 years and older is generally associated with a more aggressive clinical course and worse prognosis. Very recently, following large-scale studies, the 45-year age cut-off for cancer staging, and thus disease prognostication for differentiated thyroid cancers has been raised to 55 years . Studies have shown that this older age cut-off improves the accuracy of the prognostication system, and therefore should help prevent overtreatment of patients. The objective of this study was to review the distribution of the BSRTC diagnostic categories at our institution and to determine if patient age or gender significantly modifies the risk of malignancy in the indeterminate (AUS/FLUS, sFN, and sM) BSRTC diagnostic groups.