From the clinical perspective, detection of chromosomal abnormalities in most hematological malignancies is relevant not only for diagnostic and treatment purposes but also for prognostic risk assessment. A description of chromosomal abnormalities is included in the 2008 World Health Organization Classification of Tumors of Hematopoietic and Lymphoid Tissues  and guides the practitioner in choosing the most appropriate treatment. Furthermore, chromosomal abnormalities identification harbors a prognosis value; for example patients bearing the chromosomal translocation t(12;21)(p13;q22) generating ETV6-RUNX1 fusion gene have a better prognosis than those displaying chromosomal rearrangements in MLL gene [2, 3].