The pregnant woman underwent cord blood samplings because of the congenital malformations. Single-nucleotide polymorphism (SNP)-based chromosomal microarray analysis (CMA) (Fig. 3) was performed for prenatal genetic analysis used with fetal cord blood and parental blood samples after the normal chromosomal karyotype analysis was revealed. It detected a 0.72-Mb duplication at 4q35.2 in fetus which was associated with epilepsy (https://decipher.sanger.ac.uk/patient/290426#phenotype/patient-phenotypes) and cardiac anomalies (https://decipher.sanger.ac.uk/patient/288182#phenotype/patient-phenotypes). It encompassed the FRG1 and FRG2 genes. In addition, the CMA also revealed a 0.13-Mb deletion at 6q26 which was located inside the PARK2 gene. The mutation in the PARK2 gene (OMIM ID: ∗602544) is known to be related to autosomal recessive juvenile Parkinson disease. Neither the duplication nor deletion was inherited from the parents.