All of the articles had been published in peer-reviewed journals. Forty-three (42%) publications had statement of potential conflicts of interest. Eighty-eight (85%) articles reported compliance with animal welfare regulations. Random allocation to group was reported in 79 (77%) studies. Four (4%) studies reported blinded induction of the model. No study reported a sample size calculation method and only one study each (1%) study reported either animal exclusions or the blinded assessment of outcome (Fig 7). There was no statistically significant impact of these items on reported effect sizes for behavioural or neurochemical outcomes.