Prevalence of MN in four experimental groups is illustrated in Table 2. The mean MN frequency in control PBLs was 10 MN per 1000 binucleated cells. Similar to effect in chromosomal aberration study, the decoction by itself did not induce any excess MN. A slight statistically insignificant elevation in MN count was observed in PBLs exposed to the decoction (100–600 μg/mL), with respect to the control samples. These results suggest that the decoction at a concentration range of 100–600 μg/mL does not induce any significant damage to lymphocyte genome in vitro.