Abnormalities of the basal ganglia are frequently seen in HIV-infected (HIV+) children and adults (George et al., 2009; Hoare et al., 2014), and subcortical structures may contain the highest levels of the virus (Tornatore et al., 1994). Neuroimaging shows that HIV+ children may have shape and volume alterations in subcortical gray matter (Lewis-de los Angeles et al., 2016; Yadav et al., 2017) and calcification of the basal ganglia (Govender et al., 2011), despite ART initiation during childhood.