Clinical course and laboratory findings. The prolonged prothrombin time (PT) and partial thromboplastin time (PTT) values were consistent and factor V activity was consistently measured as low (15%); aspirin discontinuance abruptly increased the value of the area under the curve for ticagrelor from 22 to 52. AD = admission day, aPTT = activated PTT, AUC_aspirin = area under the curve for aspirin, AUC_ticagrelor = area under the curve for ticagrelor, HgB = hemoglobin, INR = international normalized ratio, IV = intravenous, PRC = packed red cell, PT = prothrombin time, PTT = partial thromboplastin time.