LPS stimulation was chosen because it is standard to study general inflammation processes in many species. Immunological stress is the status of animals challenged by bacteria or viruses. It is associated with immunological, neurological, and endocrinological responses . A four time point kinetic was studied. It has been reported that time points earlier than 24 h are more relevant to decipher the onset of the response to stimulus as shown in kinetics studies in cow , pig , mouse  or human . Moreover, kinetic studies have revealed that many genes return to their basal expression level by 24-48 h of stimulation, suggesting that homeostasis is restored at that time [59, 60]. Our results provide many candidate genes to test for kinetic studies and ongoing complementary studies focused on this topic. It is worth mentioning that the different responses to LPS are not influenced by the adrenal gland reactivity as measured by the cortisol response to ACTH.