Endophthalmitis after vitreous surgery is an uncommon but a devastating complication. The reported incidence of endophthalmitis after vitreous surgery ranges from 0.05% to 0.02% with 20-G vitrectomy.[2–10] Initial reports showed higher rates of post-minimally invasive vitreoretinal surgery (MIVS) endophthalmitis, whereas recent reports have shown a declining trend.