Spermatogenesis is the primary biological process occurring in the testis and produces mature haploid spermatozoa from diploid spermatogonia. This developmental process is complicated and involves a series of cell differentiation and biological events including spermatogonial proliferation, spermatocyte meiosis, and morphological changes of rounde spermatid12. Elucidation of the molecular mechanisms underlying spermatogenesis is important for understanding the genetic regulation of normal male germ cell development. This understanding can also direct strategies for the clinical diagnosis and treatment of male infertility. Therefore, investigation of the molecular mechanisms of testis development and spermatogenesis are prominent areas of research in the field of reproductive biology.