The average number of rewards per session, the average distance traveled to reach a reward, and the average time required to reach a reward are analyzed as a function of training time. A) The average number of rewards per session of untrained mice (Acclimation, D1-D3.5), mice after Baseline training (Baseline, D6.5-D9), and mice at the end of training (Data Acq, D19-D21.5). An ANOVA test shows that the differences among these three groups are statistically significant (F(2,75) = 62.18, P<0.001). Fisher’s PLSD post-hoc analysis shows that the differences between all three pair-wise comparisons are statistically significant (Acclimation versus Baseline, P<0.001; Acclimation versus Data Acq., P<0.001; Baseline versus Data Acq., P<0.001). B) The average number of rewards and failures during the Baseline and Data Acquisition phases. A Chi-squared test shows that the difference between these two groups is statistically significant (F = 114, P<0.001). C) The average number of rewards per session as a function of training time. D) The total distance traveled per session during the Acclimation, Baseline, and Data Acquisition phases. An ANOVA test shows that the differences among these three groups are statistically significant (F(2,75) = 63.64, P<0.001). Fisher’s PLSD post-hoc analysis shows that the differences between all three pair-wise comparisons are statistically significant (Acclimation versus Baseline, P<0.001; Acclimation versus Data Acq., P<0.001; Baseline versus Data Acq., P<0.001). E) The average distance traveled per reward during the Baseline and Data Acquisition phases. A paired Student t-test shows that the difference between these two groups is not statistically significant (df = 18, t = 0.02, P>0.05). F) The percent of the total distance traveled that resulted in rewards during the Baseline and Data Acquisition phases. A paired Student t-test shows that the difference between these two groups is statistically significant (df = 22, t = 4.69, P<0.001). G) The average time required for reaching a reward per session during the Baseline and Data Acquisition phases. A paired Student t-test shows that the difference between these two groups is statistically significant (df = 18, t = 2.24, P<0.05). In all panels except panel C, the number in each column indicates the number of test sessions of 4 mice. Data are presented in the bar graphs as mean ± SEM in this figure and all of the following figures.