The t-Student’s test with Bonferroni correction highlighted the deterioration of the knee extension during the stance phase of the gait. As shown in Fig 2, the ankle-knee-hip covariation pattern of FRDA worsened between baseline and the follow-up evaluation. This feature anticipated the loss of the locomotor function in two patients. In this pediatric cohort of FRDA patients, the knee hyperextension was the only sensitive parameter for changes in one-year. However, at the follow-up, the patients with FRDA showed a clear clinical worsening, underlined also by the average changes of several parameters and SARA scores. These changes were significant applying the t-Student’s test without correction suggesting that in this particular case the Bonferroni correction could expose to the risk of false negative rejections (type II error). In fact, the analyses without correction showed a significant worsening of the SARA score (3.3± 2.5 mean SARA score variation points). Such SARA score annual variation is quite different from that reported in a previous study by Marelli and coll., where a mean SARA score variation of 1.36 ± 2.3 points/year was described. However, this could be mainly due to different reasons: The first is that our cohort was composed of patients with early disease onset and faster worsening. The second reason is that our sample size was small, particularly at the follow-up. Further studies with larger sample size and longer follow-up will verify if this peculiar aspect of ataxic gait can be a predictive feature of locomotor status: In particular able to discriminate between independent walker and who need assistive device.