The association age- and sex-adjusted cardiometabolic factors, kidney function tests across quarters of TL analyzed are summarized in Table 2. Mean body mass index, fat-free mass, fat mass, triglyceride, total cholesterol and C-reactive protein significantly decreased across increasing TL quarters (all p < 0.001), while high-density lipoprotein cholesterol significantly increased across increasing TL quarters (p < 0.001, Table 2). eGFR significantly decreased and ACR significantly increased across increasing quarters of TL (both p < 0.001).