“The GINS subunits of the CMG-Mcm10 complex ran off the gel, but a previous study demonstrated that Mcm10 preferentially associates with the entire CMG complex (Lõoke et al., 2017). This is supported by densitometry analysis of gels showing GINS subunits in both FLAG and MonoQ purified CMG-Mcm10 complexes (Figure 2—figure supplements 3 and 4).”