While further investigations are needed to unveil the molecular details of such neuroprotection, these data point to the possibility that the proposed model may be useful in the context of therapeutic applications after brain injury. The involvement of Cxs in maintaining the delicate balance of CNS cells, via GJs and/or HCs, may indeed stimulate the development of new modulators for Cxs‐based channels as novel therapeutic agents for the cure of nervous disorders 73, 74, 75, 76.