H&E‐stained gastrocnemius muscle sections of terminal stage SOD1G93A mice with and without P110 treatment, muscle fibers presenting pathological alterations including atrophy, hypertrophy, round fibers, and fibers with central nuclei. 4‐HNE‐stained gastrocnemius muscle sections show increased staining in SOD1G93A mice as compared to either WT or P110‐treated mice. Scale bar: 50 μm.