The ocean is the elixir of life. Its composition is an excellent resource to be tapped for drug discovery. The marine environment is complex with variations in pressure, salinity, temperature and biological habitats. The marine organisms have unique therapeutic properties. These have been explored and are yet to be proved . Approximately one half of the total global biodiversity is represented by marine organisms, which are the reservoirs of active natural products . The organisms living in oceans are unique with richest sources of new drug leads. Marine sponges are said to be the gold mines for the past 50 years, with respect to the diversity of secondary metabolites. Sponges produce wide array of compounds with varying carbon skeleton, by which the diseases can be suppressed at different points on focusing specific targets. The secondary metabolites produced are biologically active molecules not directly involved in normal functions of the organisms, which includes growth, reproduction or development [2, 3].