Snx4 is a sorting nexin that controls the recycling of some late-Golgi SNAREs (i.e., Snc1) between the early endosome and the TGN (Hettema et al. 2003). Previous results suggested that Snx4 is required for a selective form of autophagy, the cytoplasm-to-vacuole transport pathway (Nice et al. 2002), although our results suggest it may also have a role in macroautophagy as well.