In conclusion, we have demonstrated that there are specific biomarkers indicative of an LPS-stimulated inflammatory response. Furthermore, these responses persist for prolonged periods of time and at significant expression levels, making them good candidate markers for evaluating the efficacy of anti-inflammatory drugs. The majority of the genes identified have known roles in the inflammatory process. Subsequently, these biomarkers may serve collectively as an indication of inflammation in swine. The knowledge gained from this series of experiments may help in the development of a model for further studies.