In the Kaplan-Meier analysis, the cumulative incidence of overall as well as PE-related death did not differ significantly between the different CTOI strata after 90 days (P = 0.46 and P = 0.79, respectively) (Fig 1). However, there was a significant association between continuous CTOI and PE-related 90-day mortality (adjusted sub-hazard ratio [SHR] per 10% CTOI increase 1.36; 95% confidence interval [CI] 1.03–1.81; P = 0.03), but not between continuous CTOI and 90-day overall mortality (adjusted hazard ratio [HR] per 10% CTOI increase 0.92; 95% CI 0.70–1.21; P = 0.54) (Table 2). In contrast to the PESI, the RV/LV diameter ratio was not associated with overall and PE-related 90-day mortality (Table 2).