Among patients admitted to our hospital with FUO, who were finally diagnosed with TB, the ratio of male to female was 1.14:1. The average age was 42.1 ± 17.5 (mean ± standard deviation [SD]) years (range 18–82 years). Among these patients, HLH incidence rate was 2.16%, with male-to-female ratio of 1:3 and an average age of 46.6 ± 19.3 years (range 23–78 years). There was a higher proportion of females among the TB-HLH patients than the proportion of females among TB patients (P = 0.001).