Field evaluations of MON-89Ø34-3 × MON-88Ø17-3, MON-89Ø34-3 × MON-ØØ6Ø3-6, and MON-ØØ6Ø3-6 were well distributed and representative of each of the five ecoregions during 2009–2013 (Fig. 1). Together, the five ecoregions represent a wide range of conditions: an altitude range of 0–2400 meters above sea level; warm to semi-warm climate, with a mean annual temperature range of 17–26 °C; and subhumid to semiarid and very dry conditions with a mean annual rainfall range of 100–1069 mm (Supplementary Table 1). However, the lack of rainfall in semiarid and very dry environments had no impact on the crop growth because all trials were under irrigation and water was provided as needed (Mendoza et al. 2003), which is a typical practice during the autumn–winter season in these northern regions. Data from each of the 36 studies (Supplementary Table 2) were individually analyzed and a subsequent meta-analysis on the individual results of each trial was carried out. Meta-analysis grouped studies in comparative panels for the two regulatory phases (Experimental and Pilot) across the five ecoregions, multiple sites, and years (2009–2013).