(5)disp¯i∈x,y,zq∈quadrants=1n∑i=1N(Pipost−Pipre) where Pipre and Pipost are corresponding points of pre- and post-surgery PCL, respectively, and N is the number of points in each PCL. The proposed HM follows the following strategy: the displacement of each point belonging to the healthy quadrants is computed based on the average displacement of each specific quadrant; for the points belonging to the unhealthy quadrant, the displacement is computed taken into account the average displacement of that quadrant, but multiplied both by {4,3,2,1} for the breast density ({A,B,C,D}, respectively), and by {3,2,1} for tumor size ({L,M,S}, respectively), following the knowledge obtained in Section 3.1 (see Equation (6)):(6)Pinew=Pi+dispi¯qPi∈healthybreastquadrantsPi+b×s×dispi¯qPi∈quadrantswhichcomprisesthetumor, where b, s, and dispi¯q are breast density, tumor size, and displacement of the equivalent breast quadrant, respectively, and finally, pinew denotes the calculated post-surgery PCL. The presented results of Table 15 are obtained by this this approach.