It has been shown that miR-484 and miR-744 may be expressed in different human cells including macrophages and dendritic cells (our unpublished observations), which are both DENV target cells, and that their expression can be regulated by external factors that alter cell homeostasis, such as diseases (Tan et al. 2015). However, despite the different studies on the expression of these miRNAs, thus far, no specific function has been attributed to either miRNA, but miR-744 was shown to enhance the IFN-I signalling pathway by targeting protein tyrosine phosphatase 1B, a ubiquitously expressed phosphatase, in primary human renal meningeal cells (Zhang et al. 2015).