The weight reducing effects of supaglutide was found to be associated with the reduction in part of visceral fat, specifically, the epididymal fat (epididymal fat: SPG vs. Ctrl = 2.45 ± 0.06% vs. 3.67 ± 0.17%, p < 001) and the mass of liver (SPG vs. Ctrl = 3.43 ± 0.04% vs. 4.57 ± 0.05%, p < 001) (Figure 2B). Interestingly, the mass in relation to body weight of other tissues examined, including brown fat, inguinal fat (which represents part of subcutaneous fat), pancreas and lower leg muscles, were not significantly changed (Figure 2B, p > 0.05).