C57BL/6 mice were purchased from Taconic (Ry, Denmark). All animal experiments were performed at least twice with 5 to 10 female animals included in each group. For testing trAb-induced tumor rejection, mice received a challenge of 105 B78-D14 or B16-EpCAM cells and were treated on day 2 and 5 with 50 μg Surek or 10 μg BiLu. 100 μg HB304 were either given simultaneously with trAbs or, in some experiments, repeatedly on days 9 and 12 followed by four other injections in weekly intervals.