In previous studies, it was shown that age was strongly related to exposure of PCBs, due to intake of PCB and long half-lives of PCBs in the human body. On the other hand, only women might excrete the PCBs through delivery and lactation. Dietary exposure to PCBs, especially in relation to fish consumption, was also reported, indicating out results that supported the previous cohort studies, even in the current Japanese cohort study. While the limitations about the smoking habits and breast-feeding existed, this study shows that the FFQ may help predict PCB levels in serum from women. In the future, development of the more accurate predictive models using information about the smoking status and breast-feeding was needed.