Other advances relate to the change in classification of pregnant women from being considered a “vulnerable” population for research, to no longer being considered “vulnerable.” This challenge for maternal immunization was addressed by the National Vaccine Advisory Committee to the Department of Health and Human Services, who also recommended the prioritization of maternal immunization as a public health strategy, and the investment in the development of vaccines for pregnant women (31). Globally, the 2017 updated International Guidelines for Health-Related Research Involving Humans of the Council for International Organizations of Medical Sciences, in collaboration with the WHO, also conclude that women must be included in health-related research, unless a good scientific reason justifies their exclusion, and that women should provide informed consent for themselves (32). Finally, the 21st Century Cures Act, as law enacted by the US Congress in December 2016 and designed to help accelerate medical product development and faster access to patients to innovations, established a task force on research specific to pregnant women and lactating women, to provide advice and guidance to the Secretary of HHS, to address gaps in knowledge and research regarding safe and effective therapies for pregnant and lactating women, and authorized substantial funds for this task (33). A key provision of this law was the inclusion of vaccines administered during pregnancy in the Vaccine Injury Compensation Program, thereby providing coverage for claims of potential vaccination adverse effects on the fetus and the mother, for providers who administer vaccines to pregnant women. Specifically, the law states that “…both a woman who received a covered vaccine while pregnant and any child who was in utero at the time such woman received the vaccine shall be considered persons to whom the covered vaccine was administered and persons who received the covered vaccine.” This provision is a tremendous step toward the improvement of acceptance, confidence, and coverage of maternal immunization in the US.