From 2013 to 2015, disease outbreaks with severe respiratory signs, including fever, coughing, sneezing, nasal discharge, and low appetite occurred in ten pig farms in Guangxi. A total of 600 nasal swabs and 135 lung tissues with or without any respiratory signs were collected from farms or slaughterhouses in Nanning, Qinzhou, Chongzuo, Laibin, Liuzhou, Bobai, Guigang, Dongxing, and Baise of Guangxi (Table 1).Table 1Details of samples collected for SIVs testing in GuangxiCityFarmStrains abbreviationSampling siteTimeClinical signsaNanning1#NN1994Farm(500 sows)2013.09Difficulty breathing; PRRSV positive2#NNLXFarm (900 sows)2014.10Fever, coughing, sneezing, nasal discharge3#NNXDFarm(600 sows)2013.01Difficulty breathing; PRRSV and PCV positiveNNXD2023Farm(600 sows)2013.09Coughing, sneezing, nasal discharge4#JGB4Farm(1000 sows)2013.09Coughing and sneezingJG1Farm(1000 sows)2014.03Coughing and sneezingChongzuo5#CZ7Farm(1000 sows)2014.10Fever, coughing, sneezingQingzhou6#QZ5Farm(3000 sows)2014.08Fever, coughing, nasal dischargeLaibing7#LB9Farm(800 sows)2014.10Fever, coughing, sneezingLiuzhou8#LZA3Farm(500 sows)2015.06Coughing and sneezingBobai9#BB2Farm(1000 sows)2014.09Coughing and sneezingGuigang10#GG6Farm(800 sows)2013.05Coughing and sneezingDongxingN/ADX24Abattoirs2013.12N/ABaiseN/ABS30Abattoirs2014.11N/AN/A not available, PCV porcine circovirusaPRRSV represents porcine reproductive and respiratory syndrome virus