The extinction of fear memory is one treatment method for post-traumatic stress disorder, because the establishment of a novel social interaction is accompanied by the extinction of previous social fear. In this study, the recovery due to social interaction was observed on day 15 after aggression, suggesting that the previous aversive stimulation was gradually diminished. Researchers have recently used a condition stimulus memory retrieval–extinction procedure to prevent fear recovery after extinction in rats and humans [32–35]. Consolidation refers to the process wherein memories are retained after their retrieval and destabilization. Destabilization refers to the return of a memory to a labile phase after memory retrieval. Researchers have inferred that memory consolidation is hampered when the expression of the conditioned responses is disrupted by post-retrieval neural pharmacological manipulations within a specific time interval (i.e., a “reconsolidation window” of up to 2 h post retrieval. This strategy effectively promoted the extinction of aversive memory, which aided in ameliorating the symptoms of mood disorders [36–38]. Our results suggested that aversive memory became extinct after 15 days without additional social defeat. Once the aversive information is forgotten, the learning ability for a novel stimulation is recovered. Another recent study found that autism is associated with genetic variation and the copy number deletion of P-Rex1, which encodes the phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor1. The genetic deletion or knockdown of P-Rex1 in the CA1 region of the mouse hippocampus produced autism-like behaviors, such as impaired social interactions, reversal learning deficits in the water maze, and extinction-resistant memory of fear conditioning [39, 40]. These behavioral changes were possibly due to impaired active forgetting or, in a general sense, the failure to update memories. Context recognition involves hippocampal function. The inhibition of the vHIP induced by social aggression disturbs the recognition of novel context and social objects at an early stage (on days 1 and 3 after social defeat). The hippocampal response to novel stimulation resulted in the recovery of the learning ability at a later stage (on days 7 and 15 after social defeat).