Recently, biodegradable polymer scaffolds have been utilized in tissue engineering to regenerate or substitute for a human organs [1, 2]. So numerous researchers had studied and utilized the 3-D scaffolds via various methods and aspects such as using various pore size . The results in many papers are emphasized and come out with numerous characteristics of the 3-D scaffold such as the pore size, porosity, and the mechanical property for tissue engineering [2–4].