Sensitivity of PC responses to differences in input spike patterns. (A) Type I BPRs were elicited using different input frequencies and burst durations. Left, the relationship between output bursts length and the duration of input burst at 100 Hz, 200 Hz, 500 Hz. A linear fitting is superimposed (R2 = 0.996, p(F) < 10−6). Right, the relationship between the burst/pause ratio (duration of burst by duration of pause) and the duration of input burst at 100 Hz, 200 Hz, 500 Hz. A linear fitting is superimposed (R2 = 0.96, p(F) < 10−4). Bottom, PC burst transmission across the 8th Ranvier node for input burst at 100 Hz, 200 Hz, 500 Hz. (B) Continuous spike frequency modulation was elicited using input spike trains with different frequencies and number of pf synapses.