Our study is subject to a series of limitations. First, the CANDIPOP study was not designed to analyze ocular candidiasis; however, we report the broadest experience to date on ophthalmoscopy in a large population of patients who were prospectively followed by an infectious disease specialist. Second, only 46% of the candidemic patients underwent ophthalmoscopy, with the result that we may have underestimated the involvement of ocular Candida infection; however, no clinical manifestations of ocular candidiasis were observed in the group of patients who did not undergo ophthalmoscopy. Finally, no patients with a history of drug addiction were included in the study.