About 21% of the adult population in the United States meet the physical activity guidelines for both aerobic physical and muscle-strengthening activity . In this population, laboratory test results that fall outside of the typical reference intervals may actually be a healthy adaptation to exercise training, which might be indicated by observing a change of results toward values considered more desirable based on risk. Accordingly, prior research has suggested the need for reference intervals more reflective of the athletic population to avoid misinterpretation of results . Thus, the purpose of this investigation was to explore the effects of type (aerobic and strength) and frequency of exercise participation on clinical laboratory tests in a large healthy young-adult population.