An exploratory research was conducted to identify key terms that can be considered as relevant value propositions for patients undergoing cancer treatment based on the review of selected publications (Epstein and Street, 2007, 2011; Pitts and Goldberg, 2015; Schnipper et al., 2015, 2016; Windham et al., 2015). Lead representatives of participant POs selected these papers partly because they had been widely discussed in global conferences and they were recommended by clinical experts. After selection of patient relevant value propositions an electronic survey was developed and completed by leaders of 19 POs from four continents to explore relative importance of these PPVs. Nine of the POs initiated this research project via the Global Action for Cancer Patients platform, and an additional 10 POs—all of them are national leaders in their own respective disease areas—joined the survey. Finally, a systematic literature review—using Pubmed as a research engine—was conducted to evaluate how clinical cancer care guidelines incorporate the identified PPVs.