Autophagy/lysosome pathway plays important roles in malignant transformation and cancer progression.15 To make the connection between miR-20a and the autophagy/lysosome pathway at a molecular level, we performed Gene Set Enrichment Analysis. The expression level of miR-20a was used as a phenotype label to identify biological processes and signaling pathways associate with it. Enrichment analysis of gene expression profiles revealed that expression of certain components of the autophagy/lysosome pathways correlate with lower expression of miR-20a (Figure 1c).