The effect of montelukast on the use of OCS was described in three trials [2, 13, 15]. In one trial , only the percentage of episodes that required OCS was presented (21% montelukast vs 24% placebo). Thus, the results could not be entered into the meta-analysis. This trial reported no significant difference between montelukast and placebo in reducing the number of OCS courses (OR, 0.80; 95% CI, 0.56 to 1.15; mean for montelukast 0.35 vs placebo 0.36 (p = 0.25)) .