The finding that the functional miR-128 binding sites are located in both the CDS of telomerase mRNA and the L1 mRNA, responsible for repressing Telomerase activity and L1 mobilization in cancer cells, supports the novel concept that one microRNA (for example miR-128) can function by parallel regulation of groups of enzymes (such as RT) by binding to conserved target sequences in the coding region of the enzymes.