While medical diagnosis has traditionally been focused on pathogens, research on the whole microbiome and its correlations with gut health continues to emerge . The test panel presented here reports on some microorganisms that are not usually interrogated in the clinic but provide additional insight into the overall gut health of a patient in a clinical setting (S2 Table). Because our detection method is based on DNA sequencing, the target panel can readily be expanded if new information about clinically important microorganisms arises. Because 16S rRNA gene sequencing identifies and quantifies the bacteria and archaea in a sample, relevant microbial metrics such as a microbiome diversity score can also be obtained, in addition to the information about individual targets, to provide a comprehensive overview of gastrointestinal health .