Although intraperitoneal injection of liraglutide (100 μg/kg) significantly suppressed food intake compared with saline controls for 2 h after injection, the acute anorexic effects of liraglutide were blunted in mice, which were pretreated with TCB-2 (Figures 4(a) and 4(b)). These findings demonstrate that pretreatment with a 5-HT2A agonist partially reverses the acute anorexic effect of liraglutide in mice.