Elevated storage temperature and time did affect the measurement results in some cases, as expected. Incubation at 40 °C for extended periods produced the most noticeable change, with an increase in protein particulate content, apparent hydrodynamic radius, and apparent concentration. SEC results at 40 °C indicated an initial decrease in HMW species, followed by an increase in LMW species beyond 7 days, resulting in the parabolic behavior of Fig. 8C under this condition. The kinetics were slowed under refrigerated conditions, however, SEC results did fall outside of the control range when stored at 4 °C for 28 days. Measurement results for all other assays were shown to be within the control limits during refrigerated storage for up to 28 days. In all cases, storage of the material at −80 °C is preferred. If aliquot preparation and/or storage at other than recommended conditions are necessary, the maximum alternative storage condition evaluated that yielded measurement results within the control range for each method is listed in ESM Table S17 for reference values and ESM Table S18 for informational values and peptide mapping.