DRESS syndrome was first defined in 1996 by Bocquet et al . It is characterized by fever, cutaneous eruption, internal organ involvement and hematologic abnormalities within 1-8 weeks after the exposure of the suspected drug . Anticonvulsants such as carbamazepine, lamotrigine, phenobarbital, phenytoin and allopurinol are the most common causes of DRESS syndrome . In a series of 172 cases of DRESS syndrome carbamazepine accounted for the greatest percentage of cases (27%), followed by allopurinol (11%), lamotrigine (6%), phenobarbital (6%), sulfasalazine (6%) .