Electron transport chain mutations are not impaired for intracellular replication. (A) The atpH::Tn strain was grown on BHI plates under oxic and anoxic conditions. (B) cydA::Tn, qoxA::Tn, and atpH::Tn strains (MOI of 0.2) were grown in BMDMs and enumerated for CFU at 2 and 5 h postinfection. Data are calculated as fold change between 2 and 5 h and representative of results from three independent experiments. The panel on the right depicts the same data but graphed as CFU at 0.5, 2, 5, and 8 h postinfection. Download FIG S7, EPS file, 1 MB.