To identify if SH‐SY5Y cells, cultured in presence or in absence of OEC‐CM in normoxic and H/R conditions, expressed some specific Cxs (including Cx47, Cx43, Cx40, Cx36, Cx32, and Cx30), we performed Western blot analyses. Our data indicated that cells grown in all experimental conditions showed no or a very low expression of Cx47, Cx32, Cx40 and Cx30 (Fig. 3A). The cultures, maintained under normoxic conditions, showed basal expression levels for Cx36 and Cx43 that were reduced in presence of OEC‐CM. H/R injured cultures showed an intensely increased Cx43 levels and OEC‐CM was able to reduce this overexpression to normoxic levels (Fig. 3A).