Sensitivity of BPR to synaptic parameters. (A) Type II BPRs were elicited by 500 Hz-10 spikes bursts using different release probabilities, p. By increasing p, the EPSCs trains changed progressively from facilitation to depression. The raster plots obtained over repeated trails reveal an increased precision of spike emission by increasing release probability, but this cannot be detected in the peri-stimulus time histograms (PSTH). (B) The CV of the ISI measured from raster plots shows a decrease both for the burst and pause by increasing p. Decaying exponential fitting is superimposed (bursts, R2 = 0.98, p(F) < 10−6; pause, R2 = 0.996, p(F) < 10−6). The histograms show the changes caused by a ±30% change in AMPA maximum conductance.