Normal and tumoral prostate biopsies were obtained from 34 patients (Table 1) diagnosed with prostate cancer at Clermont-Ferrand University Hospital (France). All biopsies were kept in nitrogen. A pathologist performed tumor evaluation. Patients did not receive chemotherapy before clinical examination. All subjects gave written informed consent to the study, which was approved by the French Ministry for Higher Education and Research (DC-2008-558).Table 1Clinical and biological characteristics of patientsCasesTTNTTotal cases (n = 34)2113Age at diagnosis (years) < 4900 50–5922 60–69118 > 7083Baseline PSA (ng/mL) < 400 4–1089 10–2084 > 2050Clinical stage T1c7- T28- T36-Gleason Score ≤ 710- > 711- TT tumoral tissues, NT normal tissues, PSA prostate-specific antigen