Third, our study, underlined the need for institutional support to encourage open science practice. The MNI is addressing researcher concerns through substantial institutional investment. The development of specialized patient consent and other REB processes, cyber and biobank infrastructure, support staff and streamlined workflow promote clear and efficient sharing (Das et al., 2016; Poupon et al., 2017). These platforms aim to support researcher trust by enabling the discretion to choose when and what to publically share and by protecting researchers’ and partners’ interests within a secure sharing environment. Likewise, the MNI recently partnered with F1000 to launch an open research platform (https://mniopenresearch.org) to allow rapid sharing of articles, data and other outputs. The MNI also offers a stipend to support the use of the platform and for open access publication in journals of the researcher’s choice. These resources are designed to reduce barriers to participation, acting as carrots rather than sticks to encourage open science practices (Ferriera, 2008; Leonelli et al., 2015). Tracking the impact of explicit institutional policy and resources compared to their absence will yield important information on the conditions needed to enhance open practices.