The CTOI had a poor, the PESI a good predictive accuracy for 90-day overall mortality (C-statistics 0.43 and 0.79, 95% CI 0.28–0.57 and 0.71–0.87, respectively). Further, the CTOI and the PESI had a similar predictive accuracy for PE-related 90-day mortality (C-statistics 0.69 and 0.70, 95% CI 0.52–0.85 and 0.61–0.79, respectively). In contrast, the predictive accuracy of the RV/LV diameter ratio for overall and PE-related 90-day mortality was poor (C-statistics 0.39 and 0.51, 95% CI 0.25–0.52 and 0.36–0.66, respectively).