Singing as practiced in Western cultures has received increasing scientific interest during the last decades. Several studies indicate a connection between singing as a means of self-expression, regulation of emotions, and health and well-being [57–59]. Moreover, the availability of psychobiological methodology over the last decades such as the ambulatory assessment of humoral stress markers or functional imaging have confirmed that the experienced stress releasing effects of music have indeed a psychophysiological bases . As Hou in his review elucidates, music-evoked emotions can modulate activities in both cortical and subcortical systems, and across cortical-subcortical networks . Exactly these networks, which extend from the anterior cingulate gyrus to the amygdala are integral and essential to the generation and regulation of emotions. It is particularly interesting that these networks exhibit disturbed functioning in mental and emotional psychiatric disorders.