Vulnerability to water-related impacts of climate change and extreme weather are already felt in all major sectors and are projected to intensify in the future, for example, in agriculture (high confidence) (Sections 4.3.1, 4.5.1); energy and industry (high confidence for observed drought impacts and projected impacts) (Sections 4.3.2, 4.5.2); water for health and sanitation (high confidence about links to precipitation extremes and disease outbreaks) (Sections 4.3.3, 4.5.3); water for urban, peri-urban and municipal sectors