Evaluation of Free Gingival Graft Timing
This clinical trial aims to compare and evaluate the clinical outcomes between two distinct treatment sequences: free gingival graft surgery preceding guided bone regeneration and guided bone regeneration followed by free gingival graft.
- EligibilityCriteria: Inclusion Criteria:  • At least 18 years old  No uncontrolled medical conditions or medications that will affect their bone healing. Good oral hygiene is defined as a full-mouth plaque score ≤25%11. Must be able to read and understand the informed consent document. Has a need for implants to replace missing tooth/teeth in at least 1 quadrant of the mouth. Insufficient alveolar ridge width for endosseous implant placement, defined as 5 mm or less, as determined by bone sounding and CBCT scan. The patient and/or guardian is willing and able to comply with pre-operative and post-operative diagnostic and clinical evaluations required. The patient is not pregnant or breastfeeding.  Exclusion Criteria:  Active infectious diseases.  Liver or kidney dysfunction/failure. Uncontrolled diabetes (HbA1c ≥ 8.5). Active cancer treatment - such as active chemotherapy radiation therapy, or radiotherapy performed within ≤12 months from the procedure. Taking medications that will affect their bone healing (for example, bisphosphonates and long-term anti-inflammatory medications). Metabolic bone diseases that affect bone healing such as osteoporosis. Pregnant or lactating women (self-reported). Current tobacco and Marijuana smokers have 10 or more cigarettes per day, and former smokers (&gt; 10 cigarettes) who quit &lt; 10 ago (self-reported). Poor oral hygiene. Vertical loss of bone at the edentulous ridge. History of periodontal disease. The patient is pregnant or breastfeeding - HealthyVolunteers: Accepts Healthy Volunteers - Gender: All - MinimumAge: 18 Years - StdAgeList: Adult, Older Adult