Cardiac Denervation Ablation Strategy for Severe Sinus Bradycardia
This is a prospective clinical observation and registration study. The investigator aimed to evaluate the efficacy and safety of cardiac denervation ablation as a treatment strategy for severe sinus bradycardia.
- EligibilityCriteria: Inclusion Criteria:  Sinus bradycardia and pacemaker implantation indication: long interval with mean heart rate <45 bpm or 3s recorded within 6 months before inclusion; Negative atropine test: sinus heart rate> 90bpm after atropine injection SSB related symptoms: dizziness, palpitations, fatigue, amaurosis, syncope, etc. Age ≥18 and <60 years old; The patient has agreed to participate in this trial and has signed the informed consent form.  Exclusion Criteria:  Previous history of atrial arrhythmia ablation or surgical procedure; Structural heart disease, chronic liver and kidney dysfunction, diabetes mellitus, neurological diseases.; Drug-related SSB; presence of left atrial thrombus; Pregnant women. - HealthyVolunteers: No - Gender: All - MinimumAge: 18 Years - MaximumAge: 60 Years - StdAgeList: Adult - StudyPopulation: SSB patients undergoing cardiac denervation ablation - SamplingMethod: Probability Sample