Impact of Keratinized Mucosa Augmentation on Treatment Outcomes of Peri-implant Mucositis
This study aims to observe the effects of keratinized mucosa width on peri-implant tissues by evaluating clinical and biochemical parameters. The main question it aims to answer is:

Would increasing the width of the keratinized mucosa with free gingival graft (FGG) in peri-implant mucositis be beneficial in terms of clinical periodontal parameters and peri-implant crevicular fluid levels of inflammatory cytokines compared to non-surgical therapy alone?

Our study consists of 4 groups:

Peri-implant healthy group with sufficient keratinized mucosa (≥ 2mm) (n=16), peri-implant mucositis group with sufficient keratinized mucosa (n=16), peri-implant mucositis group with insufficient keratinized mucosa (< 2mm) receiving only non-surgical treatment (n=16), peri-implant mucositis group with insufficient keratinized mucosa receiving FGG in addition to non-surgical treatment (n=16). Clinical and biochemical measurements will be recorded at the baseline, 1st month, 4th month and 7th month of the study. Peri-implant crevicular fluid samples will be collected at baseline, 1st month, 4th month and 7th month. IL-1β, RANKL, OPG levels, and RANKL/OPG ratio will be analyzed from collected samples.

Researchers will evaluate the possible benefits of FGG application in addition to non-surgical therapy by comparing the biochemical and clinical changes in areas with and without FGG application in the treatment of peri-implant mucositis.
- EligibilityCriteria: Inclusion Criteria:  Individual dental implants with a fixed prosthetic restoration that has been functional for at least 1 year No systemic disease and medication use that may affect periodontal or peri-implanter tissues Not receiving periodontal treatment in the last 6 months Volunteering to participate in the study  Exclusion Criteria:  Prosthetic restorations with an excessive contour which do not allow peri-implant pocket measurement Being pregnant or breastfeeding, Autoimmune and/or inflammatory diseases of the oral cavity, Active periodontal disease Smokers (≥ 10 cigarettes per day) Improperly positioned implants - HealthyVolunteers: Accepts Healthy Volunteers - Gender: All - MinimumAge: 18 Years - StdAgeList: Adult, Older Adult