Plants Optimizing Development Study (PODS)
This study aims to conduct a randomized clinical trial to measure the effects of a 3-month daily mixed-soy food intervention vs. a control group receiving isocaloric foods on reproductive hormones, body composition, metabolic risk, fecal microbiota, and cognition among 8-11-year-old children. Additionally, this study will assess soy food intake immediately following participation in the clinical trial to determine changes in soy food acceptance in children.
- EligibilityCriteria: Inclusion Criteria:  Child assent and parent/guardian consent Free of any food allergy 8-11 years of age Tanner scale score of ≤ 2 20/20 or corrected vision No antibiotic usage in the past 3 months ≤1 serving/d of soy food habitual consumption  Exclusion Criteria:  Non-assent or consent by child assent and/or parent/guardian Presence of any food allergy Younger than 8 years or older than 11 years Presence of specific neurological and genetic disorders (i.e., Autism, Cerebral Palsy, Multiple Sclerosis, Down syndrome) Presence of endocrine, metabolic, and gastrointestinal disease e.g., hypertension, diabetes, celiac disease Tanner scale score of > 2 Not 20/20 or uncorrected vision Antibiotic usage in the past 3 months >1 serving/d of soy food habitual consumption - HealthyVolunteers: Accepts Healthy Volunteers - Gender: All - MinimumAge: 8 Years - MaximumAge: 11 Years - StdAgeList: Child