Application of L-PRF in Periodontal Surgery
The study will compare the clinical outcomes of the two procedures, open flap debridement (OFD) compared to open flap debridement with leukocyte and platelet-rich fibrin (L-PFR) as well as differences in patient postoperative pain perception.
- EligibilityCriteria: Inclusion Criteria:  Patients between age 18 and 89 Patients needing open flap debridement procedures for periodontal disease in one or more teeth in the same arch bilaterally (split mouth) Patients must be nonsmokers, former smokers, or current smokers who smoke <10 cigarettes per day, by self-report Female patients to include non- pregnant women of child-bearing potential.  Exclusion Criteria:  Patients who disclose that they will not be able to cooperate with the follow-up schedule. Patients who are mentally incompetent, prisoners, or pregnant (as obtained via chart review or self-report) Pregnant women or women intending to become pregnant during the study period Smokers who smoke > 10 cigarettes per day - HealthyVolunteers: Accepts Healthy Volunteers - Gender: All - MinimumAge: 18 Years - MaximumAge: 89 Years - StdAgeList: Adult, Older Adult