Esketamine vs Remimazolam for Postoperative Sleep Disturbance and Anxiety
To explore and compare the effects of esketamine and remimazolam on postoperative sleep disturbance in patients undergoing oocyte retrieval
- EligibilityCriteria: Inclusion Criteria:  Age 18-45 years old; American society of Aneshesiologists（ASA）physical status classification system is grade I-III; Elective surgery is proposed BMI of 19-30 kg/m2; Patients who agreed to enroll in this study voluntarily  Exclusion Criteria:  Those who are known to be allergic to the drug ingredients in this study and their allergic constitution; Allergic history of general anesthesia drugs, opioid drugs, non-steroidal drugs; History of neurological diseases; History of chronic pain; Drug and alcohol addiction; A long history of opioid use; Opiates were given 48 hours before surgery Coronary heart disease, bronchial asthma, severe hypertension, severe blood system dysfunction, liver and kidney function, electrolyte abnormalities; Respiratory insufficiency, respiratory failure; BMI<18 kg/m2 or BMI>30kg/m2; Poor compliance, unable to complete the experiment according to the study plan; Participants who have participated in clinical trials of other drugs within the last 4 weeks; Preoperative Pittsburgh Sleep Quality Index (PSQI) higher than 7 Any circumstances deemed unsuitable for inclusion by the researcher for any reason. - HealthyVolunteers: No - Gender: Female - MinimumAge: 18 Years - MaximumAge: 45 Years - StdAgeList: Adult