Cerebellar rTMS in Patients With Multiple Sclerosis
To determine the efficacy of high frequency cerebellar repetitive transcranial magnetic stimulation on coordination in patients with multiple sclerosis.
- EligibilityCriteria: Inclusion Criteria:  Clinically definite MS (relapsing, remitting and secondary progressive) patients Patients who are medically stable and Free from relapses three months before Ambulant patients without an assistive device and score less than 5 on the Kurtzke Expanded Disability Status Scale (EDSS) Patients receiving their disease modifying drugs but no medication changing during the previous three months. Patients who had MRI evidence of lesions in the cerebellum or in the cerebellar pedunculi. Right handed patients. Severity of ataxia range from 4 to 10 according to scale of assessment and rating ataxia (SARA). Did not apply cerebellar transcranial magnetic stimulation before.  Exclusion Criteria:  Any other neurological deficits or orthopedics abnormalities. Ataxic manifestations for other cause rather than Multiple Sclerosis. Other neurological manifestations (e.g. spasticity, visual loss) Secondary musculoskeletal complication such as contractures or deformities. Cardiovascular, pulmonary, hepatic, renal, hemopoietic and thyroid diseases. Pregnant women. Addicted individuals. Previous surgeries in the brain. Any magnetic or metallic devices implanted (like cochlear implants) . Psychotic deficits or history of epileptic seizures. - HealthyVolunteers: No - Gender: All - MinimumAge: 20 Years - MaximumAge: 45 Years - StdAgeList: Adult