Effects of a Combined Exercise Intervention on the Gut Microbiome of People With Type 2 Diabetes
The goal of this experimental trial is to learn about the changes in bacterial diversity in individuals with type 2 diabetes who perform endurance and strength training at different intensities.

Participants with type 2 diabetes will be randomly assigned to 16 weeks of either moderate-intensity endurance and strength training or high-intensity endurance and strength training.

Researchers will compare the moderate-intensity and high-intensity exercise groups for differences in glycemia and bacterial diversity.
- EligibilityCriteria: Inclusion Criteria:  Adults aged 19 - 64 years old; Diagnosed with type 2 diabetes; An HbA1c >= 7.5%; Not currently meeting the recommended levels of physical activity for optimal health (i.e., 150 minutes of moderate-to-vigorous physical activity and 2+ days/week of resistance training); Average less than 10,000 steps per day over the last seven days; No change in diabetes medications over the last three months.  Exclusion Criteria:  Not diagnosed with type 2 diabetes; Partaking in a self-reported regular exercise regimen, defined as consistent participation in running or jogging activity, attending exercise classes every week, or averaging 10,000 steps per day or more over seven days; Currently performing two days of resistance training per week; Having an injury that would prevent safe participation in the intervention; A self-reported diagnosis of low iron concentrations, anemia, or being treated for these conditions; A diagnosis of any red blood cell altering condition (i.e., sickle cell anemia, poikilocytosis); Currently living with any cardiovascular disease which would impact the ability to participate in exercise safely; Currently prescribed any medication which would impact the ability to use a heart rate monitor to accurately track intensity. - HealthyVolunteers: No - Gender: All - MinimumAge: 19 Years - MaximumAge: 64 Years - StdAgeList: Adult