Comparison Between Drinking Water and Normal Saline in Irrigating Traumatic Wound
There is a controversy regarding the roles of the Normal saline and Tap water in irrigation of the wound. It has been suggested that antiseptic solution including normal saline has cytotoxic effect while tap water damages the fibroblast. There are no high level evidence to support one type of solution over other, systematic review have found no difference in wound infection between irrigation with normal saline vs tap water. There are ten randomized controlled trial comparing tap water with normal saline for irrigating wound published between 1992 to 2016. These RCT are analyzed in three systemic review and meta-analysis published on 2016, 2019, 2022, which showed that tap water and normal saline has no difference in terms of infection rate. The infection rate observed in various studies ranges from 0-11.5% in normal saline group and 0-12.6% in tap water group with no statistically significant difference.
- EligibilityCriteria: Inclusion Criteria:  Laceration wound presenting within 6 hours of duration Lacerations involving upper and lower limbs, scalps, head and neck  Exclusion Criteria:  Lacerations involving, lips, ears, mucosal surface, perineal and peri anal region Punctured or penetrating wound Bite wounds by human or animals or snakes Dirty wound requiring surgical debridement Patient requiring irrigation of wound with more than 1 liter of fluid Wounds involving tendon, joint or bone Wound associated with open fracture Patient on corticosteroid, antibiotics or immunosuppressant Patient who are not able to come for follow-up Immunocompromised patient Patient with history of significant peripheral vascular disease - HealthyVolunteers: No - Gender: All - StdAgeList: Child, Adult, Older Adult