Modulating Energy Density in Time-Restricted Eating
The goal of this randomized controlled trial is to test the effect of time-restricted eating (14-hour fast, 10-hour eating window) of a low-energy dense diet (reduced calories per gram of food) in older adults with obesity and insulin resistance. The study aims to determine if modulating the energy density of the diet reduces:

Insulin resistance and
Body weight.

Researchers will compare the groups:

Following time-restricted eating and given a diet reduced in energy density or
Following time-restricted eating and given a diet typically consumed in this population
- EligibilityCriteria: Inclusion Criteria:  Body mass index (BMI) ≥ 30kg/m2. Mini-Mental State Examination (MMSE) > 25 Geriatric Depression Scale-15 (GDS-15) < 9 Homeostatic model assessment of insulin resistance (HOMA-IR) ≥ 3.  Exclusion Criteria:  Diagnosis of Type 2 diabetes received more than five years ago Diagnosis of type 1 diabetes Evidence of clinically significant renal dysfunction or disease History of malignancy during the past five years Being treated with systemic steroids, olanzapine, or clozapine Being treated with prescription medications for obesity Being treated with thiazolidinediones, glucagon-like-receptor agonists, Dipeptidyl Peptidase IV inhibitors, and insulin Weight change > 3 kg in the preceding three months Any disease or condition that precludes testing of the study outcomes or makes it unsafe to consume the foods being tested in the study, or subjects are otherwise deemed to be unsuitable for participation in the study (determined by the investigative team) - HealthyVolunteers: No - Gender: All - MinimumAge: 50 Years - MaximumAge: 75 Years - StdAgeList: Adult, Older Adult