AKI Risk Factors Analysis After Intentional Hypotensive Anesthesia
This project investigates intentionally hypotensive management such as NTG (nitroglycerin) or NTG+Trandate during general anesthesia in patients undergoing orthognathic surgery. Throughout the entire surgical procedure, blood biochemical and urine monitoring will be conducted. Serum creatinine (Cr) levels, urine analysis, and perioperative monitoring will be utilized as indicators for assessing renal function during the surgery. The objective is to assess its potential renal injury and identify early risk factors for acute kidney injury (AKI). Timely recognition of these factors will allow for the implementation of appropriate intervention strategies, aiding in the prevention of postoperative acute kidney injury. This approach contributes to achieving the goals of Enhanced Recovery After Surgery (ERAS) for surgical patients, promoting faster postoperative recovery.
- EligibilityCriteria: Inclusion Criteria:  America society anesthesiologist classification class I to II patients undergoing oro-maxillo-facial surgery unlimited mouth opening  Exclusion Criteria:  patients with arthritis with limited mouth opening persistent liver dysfunction chronic renal insufficiency body mass index ≧35 kg/m2. past history of malignant hyperthermia or personal or family history diabetes with insulin treatment essential hypertension without controlled - HealthyVolunteers: No - Gender: All - MinimumAge: 18 Years - MaximumAge: 65 Years - StdAgeList: Adult, Older Adult - StudyPopulation: Patients without obviously systemic diseases who presentation of abnormal oro-maxillofacial anatomy needs to be corrected. - SamplingMethod: Non-Probability Sample