Effect of Antioxydant-enriched Media on Blastocyst Euploidy Rates.
One of the most sensible factors in IVF culture conditions is the susceptibility of gametes and embryos to an induced increase in reactive oxidative species (ROS) caused by the artificial environment. This study aims to evaluate the impact of using antioxidant-supplemented media during culture to evaluate embryo ploidy rates in a prospective randomized trial using sibling oocytes.
- EligibilityCriteria: Inclusion Criteria:  Patients undergoing assisted reproductive technology cycles when ICSI is indicated. Patients when Iin vitto fertilization (IVF) is also performed will be included as far as there are enough oocytes for ICSI randomization. However, IVF oocytes will not be used for the study. Maternal age 18-43 years old. PGT-A cycles with only trophectoderm biopsies on day 5/6/7. Patients with more than 6 COCs expected for ICSI. Body mass index <35. Fresh and frozen ejaculated sperm.  Exclusion Criteria:  PGT-M cycles Fresh and frozen testicular sperm. - HealthyVolunteers: Accepts Healthy Volunteers - Gender: All - GenderBased: Yes - MinimumAge: 18 Years - MaximumAge: 43 Years - StdAgeList: Adult