The LINFU® U.S. Registry in Patients With IPMN (Intraductal Papillary Mucinous Neoplasm of the Pancreas)
In this study, LINFU® will be evaluated in patients who have been identified with IPMN to determine if it can be used to help identify early, pancreatic ductal adenocarcinoma and its noninvasive precursor lesions (dysplasia). The study will also help determine if LINFU® results in earlier intervention, treatment and improvement in patient outcomes.
- EligibilityCriteria: Inclusion Criteria:  Both males and females will be enrolled and must be at least 18 years of age and under age of 90 Patients with a documented history of IPMN by any imaging method. All patients must undergo contemporaneous imaging (within 90 days before or after the LINFU® procedure) with one or more of the following: EUS, CH-EUS, CEUS, MRI/MRCP, PET/CT, CT Patients undergoing EUS-FNA may be enrolled but the FNA must be performed after the LINFU® procedure Institutional Review Board (IRB)-approved consent must be signed by patients to participate in this study.  Exclusion Criteria:  Patient under the age of 18 and over the age 90  Contraindications to LINFU® as determined by study investigators:  Patient with uncorrectable coagulopathy Patient that cannot undergo anesthesia due to cardiopulmonary contraindication as deemed by the anesthesiologist Unstable medically (cardiopulmonary, neurologic, or cardiovascular status) Patients with IPMN that has been subjected to FNA or biopsy prior to the LINFU procedure Patients with pancreatic cystic neoplasms other than IPMN i.e. mucinous cystic neoplasms, serous cystic neoplasms and other rare cystic lesions Pregnant females will be excluded Patient that is unable to provide informed consent Patient with known allergy to the microbubble contrast agent or secretin  Study Design Overview: - HealthyVolunteers: Accepts Healthy Volunteers - Gender: All - MinimumAge: 18 Years - MaximumAge: 90 Years - StdAgeList: Adult, Older Adult - StudyPopulation: Patients with a documented history of IPMN by any imaging method. - SamplingMethod: Non-Probability Sample