Secondary Access - FEmoral or Radial in Transcatheter Aortic Valve Implantation?
Transcatheter aortic valve implantation (TAVI) is a well known safe treatment for severe aortic stenosis. To perform TAVI safely, there is a need for two vascular entry (access) sites: the primary and secondary access sites. While the femoral approach remains the most common site for primary access, secondary access (which is needed for guidance during the procedure) has drawn little attention in trials of TAVI. The two secondary access sites most commonly used are the radial (through an artery in the wrist) and femoral (through an artery in the groin) access sites. Observational studies comparing the two have shown a lower risk of complications with radial access compared to femoral access, but there are no randomized controlled data to confirm these findings. Accordingly, investigators aim to undertake a multicenter, randomized controlled trial among patients who are undergoing transfemoral TAVI, to assess if radial access is superior to femoral access as a secondary access site.
- EligibilityCriteria: Inclusion Criteria:  Age >18 years Undergoing transfemoral TAVI with any commercially available transcatheter heart valve Suitable radial and secondary femoral access  Exclusion Criteria:  Primary arterial access via surgical cut-down Inadequate contralateral femoral artery access and/or bilateral radial artery access as determined by the interventional cardiologist Previously failed attempt to access bilateral radial arteries. Patient on hemodialysis - HealthyVolunteers: No - Gender: All - MinimumAge: 18 Years - StdAgeList: Adult, Older Adult