Protective Effect of Indocyanine Green Fluorescence Imaging Technology on Parathyroid Glands During Total Thyroidectomy
Accurate identification and evaluation of the parathyroid glands (PGs) intraoperatively is critical to reduce the incidence of postoperative hypoparathyroidism after total thyroidectomy. Near-infrared fluorescence imaging (NIFI), including the autofluorescence (AF) and indocyanine green fluorescence (ICGF) imaging, is a promising technique to protect PGs. This study aimed to assess whether the combined use of AF and ICGF could reduce the incidence of postoperative hypoparathyroidism and improve the identification and evaluation of PGs during total thyroidectomy.
- EligibilityCriteria: Inclusion Criteria:  Male or female patients, aged 18 years and above Scheduled for elective total or hemi thyroidectomy Normal liver and renal function No known hypersensitivity for iodine or ICG Able to understand the nature of the study procedures Willing to participate and give written informed consent  Exclusion Criteria:  Age < 18 years Liver or renal insufficiency Known ICG, iodine, penicillin or sulfa hypersensitivity Pregnancy or breastfeeding Not able to understand the nature of the study procedure Not willing to participate - HealthyVolunteers: No - Gender: All - MinimumAge: 18 Years - MaximumAge: 60 Years - StdAgeList: Adult