Comparison of 2 Extracts of Saw Palmetto Versus Placebo on BPH Symptoms
A randomized, double-blind, placebo-controlled, parallel group study to compare 2 extracts of saw palmetto versus placebo on the symptoms of benign prostate hyperplasia (BPH) in 120 generally healthy participants, 45 - 80 years.
- EligibilityCriteria: Inclusion Criteria:  Male aged between 45-80 Medically diagnosed with BPH (Participant to provide written evidence of medical diagnosis) Score of 12-19 in the IPSS (moderate) Generally healthy Able to provide informed consent Agree not to participate in another clinical trial while enrolled in this trial Agree not the change their diet or exercise while enrolled in this trial  Exclusion Criteria:  Serious illness e.g., mood disorders such as depression, anxiety or bipolar disorder, neurological disorders such as MS, kidney disease, liver disease or heart conditions (A serious illness is a condition that carries a risk of mortality, negatively impacts quality of life and daily function and/or is burdensome in symptoms and/or treatments) Unstable illness e.g., diabetes and thyroid gland dysfunction (An unstable illness is any illness that is currently not being treated with a stable dose of medication or is fluctuating in severity) Have used a drug/natural therapy for BPH or other urological symptoms within the last 30 days? Have had a urinary infection in the last 30 days or have, chronic urinary tract infections, or diagnosed chronic prostatitis Have had urogenital surgery within the last 6 months. Have had a bladder biopsy and/or cystoscopy and biopsy within the past 30 days. Have been diagnosed with chronic persistent local pathology (e.g. interstitial cystitis, bladder stones) Receiving/ prescribed Coumadin (Warfarin) or other anticoagulation therapy Diagnosed genital anatomical deformities, uncontrolled diabetes mellitus, and history of spinal cord injury, uncontrolled psychiatric disorder, and/or abnormal secondary sexual characteristics. Diagnosed cancer including prostatic cancer; if suspected by the investigator, refer for medical assessment Active smokers and/or nicotine or drug abuse Chronic alcohol use (>14 alcoholic drinks week) Allergic to any of the ingredients in investigational, comparator or placebo formula Any condition which in the opinion of the investigator makes the participant unsuitable for inclusion Participated in any other clinical trial during the past 1 month - HealthyVolunteers: No - Gender: Male - MinimumAge: 45 Years - MaximumAge: 80 Years - StdAgeList: Adult, Older Adult