Glycocalyx Monitoring in Major Abdominal Surgery
The study of the microcirculation and glycocalyx could be an essential element in the monitoring of our patients undergoing major abdominal surgery. It would enable us to better target the objectives of anaesthesia and resuscitation, which until now have been based essentially on macro-circulatory parameters.
- EligibilityCriteria: Inclusion Criteria:  For the HIPEC group :  Adult patients Age < 75 years Receiving HIPEC for primary or secondary peritoneal carcinosis  For the CDP group :  Adult patient Age < 75 years Receiving CDP for pancreatic neoplasia Patient who has read and understood the information letter and does not object to taking part in the study Patient affiliated to a social security scheme  Exclusion Criteria:  Secondary distant peritoneal metastases Chronic heart failure Chronic liver failure at stage C of the Child-Pugh score Stage IV or V chronic renal failure Inflammation of the sublingual buccal mucosa or injury that may locally influence sublingual microcirculation Patient refusal Person deprived of liberty by an administrative or judicial decision or person placed under court protection or guardianship - Gender: All - MinimumAge: 18 Years - MaximumAge: 75 Years - StdAgeList: Adult, Older Adult - StudyPopulation: Patient undergoing major abdominal surgery by cytoreduction combined with an intraperitoneal chemotherapy bath (HIPEC) or cephalic duodeno-pancreatectomy (CDP) with epidural analgesia planned in accordance with the department's usual practice - SamplingMethod: Probability Sample