Selected Immunological Indicators and Microbiota in Patients With Premature Birth and Preeclampsia
The goal is to demonstrate the relationship of the circulating pool of T-regulatory lymphocytes in the mother's peripheral blood with populations in the placentas and to compare with controls, what is the difference in the expression of individual regulatory molecules of T-regulatory lymphocytes according to new paradigms. The proportional and functional characteristics of T-regulatory lymphocytes will be correlated with the composition of the intestinal and vaginal microbiota.
- EligibilityCriteria: Inclusion Criteria:  singletone pregnancy gestational age 9+0 - 12+0 history of preeclampsia (PE) history of spontaneous preterm birth (PTL = preterm labour) history of pPROM (preterm premature rupture of membranes).  Exclusion Criteria:  uterine malformations gestational age out of 9+0 - 12+0 age out of 19-40 - Gender: Female - MinimumAge: 19 Years - MaximumAge: 40 Years - StdAgeList: Adult - StudyPopulation: Pregnant women - SamplingMethod: Probability Sample