The Link Between Human Cytomegalovirus Gene Expression and Glutamate Level in Migraine;Relation to Vitamin D Deficiency
To correlate serum 25(OH)-vitamin D level with duration, frequency, and severity of migraine headache attacks
To evaluate the relationship between the serum level of vitamin D and other indices in patients with migraine.
To correlate the serum level of glutamate with gene expression of in migraine
- EligibilityCriteria: Inclusion Criteria:  Selected patients fulfilled the criteria for diagnosis of migraine headache based on International Classification of Headache Disorders-II (ICHD-II) diagnostic criteria. The age of the selected patients ranged between 15 and 55 years of both sexes Able to give informed consent.  Exclusion Criteria:  b. Exclusion criteria:  presence of neurological disease other than migraine presence of other chronic medical conditions Participants in both groups were excluded from the study if they consumed vitamin D supplements in the preceding 3 months (any dose); or if they were taking medications that could affect vitamin D serum level such as glucocorticoids, thiazide diuretics, or statins. 4)patients refuse to participate in the study - HealthyVolunteers: Accepts Healthy Volunteers - Gender: All - MinimumAge: 15 Years - MaximumAge: 55 Years - StdAgeList: Child, Adult - StudyPopulation: Selected patients fulfilled the criteria for diagnosis of migraine headache based on International Classification of Headache Disorders-II (ICHD-II) diagnostic criteria.  And The age of the selected patients ranged between 15 and 55 years of both sexes - SamplingMethod: Non-Probability Sample