Ultrasound-guided Botulinum Toxin Injection on Cricopharyngeal Muscle Dysfunction
Ultrasound-guided injection is a visual, convenient, and radiation-free technique that allows real-time observation of the needle insertion process and drug injection location. The combination with a balloon for fixation further enhances the precision of the injection. In this study, we employed ultrasound-guided injection combined with balloon localization for cricopharyngeal muscle botulinum toxin injection treatment and conducted clinical observations.
- EligibilityCriteria: Inclusion Criteria:  Videofluoroscopic swallowing study (VFSS) confirming incomplete/opening dysfunction of the cricopharyngeal muscle; No significant improvement in swallowing function after standardized rehabilitation treatment for more than 2 weeks (unchanged or decreased FOIS); Presence of swallowing initiation, with VFSS showing that the upward movement of the hyoid bone during swallowing is greater than half the height of the C3 vertebral body; Stable vital signs, alert consciousness, and cooperation with treatment;  Exclusion Criteria:  Patients with severe cognitive impairments, psychiatric disorders, and severe cardiopulmonary diseases; Abnormalities in the pharynx and larynx structures; Patients with malignant tumors; Patients with infections or wounds at the injection site; Patients allergic to botulinum toxin; Patients with bleeding tendencies or coagulation disorders. - HealthyVolunteers: No - Gender: All - MinimumAge: 18 Years - StdAgeList: Adult, Older Adult