Clinical Trial of Metal-Reinforced Teeth Designed for Endoscopic Clips
Postoperative gastrointestinal complications following ESD, EMR, and EFTR procedures, such as gastrointestinal bleeding, diverticula, fistulas, perforations, and stent fixation, can be effectively treated through gradual endoscopic procedures. The technical limitations of traditional endoscopic hemoclips restrict their application. Although endoscopic suturing techniques are emerging, most are still in the exploratory phase. Therefore, the investigators have developed metal-reinforced teeth for hemoclips. This initial clinical study aims to validate the safety, feasibility, and effectiveness of reinforced teeth in clinical applications. The investigators also aim to explore the uses and limitations of this technology. The primary outcomes are the technical success rate and the clinical success rate.
- EligibilityCriteria: Inclusion Criteria:  1. Gastrointestinal lesions that require clips include non-variceal upper gastrointestinal bleeding, post-endoscopic submucosal dissection (ESD) lesions in the gastrointestinal tract, fistulas, diverticula, perforations, and anchoring of self-expanding metal stents. 2. Expected survival greater than 30 days; 3. Written informed consent.  Exclusion Criteria:  1. Patients with diffuse gastrointestinal lesions, such as Crohn's disease and ulcerative colitis; 2. Patients who clearly require surgical intervention; 3. Serious cardio-pulmonary, hepatic or renal disease; 4. Intolerance to endoscopy; 5. Pregnant or lactating women. - HealthyVolunteers: No - Gender: All - MinimumAge: 18 Years - MaximumAge: 90 Years - StdAgeList: Adult, Older Adult - StudyPopulation: Meet the inclusion and exclusion criteria. - SamplingMethod: Probability Sample