Risks of Intermittent Fasting in Patients With Primary Adrenal Insufficiency
In primary adrenal insufficiency, there is an increased risk of hypoglycaemia and dehydration. These risks have been little studied particularly during intermittent fasting. The present study aimed to assess these risks in a prospective study of 30 subjects with primary adrenal insufficiency. Patients will undergo a clinical examination, blood sampling and continuous glucose monitoring for fourteen days (one week of fasting and one week of non-fasting).
- EligibilityCriteria: Inclusion Criteria:  Primary adrenal insufficiency Disease duration of at least one year Substituted with hydrocortisone and fludrocortisone Wishing to fast during the month of Ramadan 2024  Exclusion Criteria:  Diabetes mellitus Renal insufficiency Hepatic insufficiency Cardiac insufficiency Respiratory insufficiency Use of hypoglycaemic agents Use of diuretics Use of glucocorticoids other than those prescribed for replacement Poor control of the disease (asthenia, malaise, melanoderma, discontinuation of treatment, etc.) Pregnancy Breast-feeding. - HealthyVolunteers: No - Gender: All - MinimumAge: 20 Years - MaximumAge: 65 Years - StdAgeList: Adult, Older Adult