Corticosteroids in Carpal Tunnel Syndrome. Prospective Randomised Controlled Non-inferiority Study
The goal of this prospective, randomised, controlled, non-inferiority analytical study is to compare the Boston score in patients treated with systemic (intramuscular) versus local infiltration corticosteroids in mild and moderate carpal tunnel syndrome in patients over 18 years of age with mild or moderate carpal tunnel syndrome.

The main questions it aims to answer are:

What is the effectiveness of intramuscular injection of corticosteroids compared to local infiltration in the treatment of mild/moderate carpal tunnel syndrome?
What are the adverse effects and application site pain associated with each route of administration?

Patients who meet the inclusion criteria will be asked to participate in the study and sign an informed consent form.

The Redcap randomizer will be used to assign the patient to one of the branches.

Researchers will compare

Branch A: patients treated with local corticosteroid infiltration in carpal tunnel under ultrasound
Branch B: patients treated with intramuscular corticosteroid injection.

Researchers will:

Compare Boston Carpal Tunnel Questionnaire score at 1.5 months, 3 months, 6 months and 12 months post-procedure.
Describe adverse reactions associated with the route of administration.
Compare the pain at the site of application associated with the route of administration.
- EligibilityCriteria: Inclusion Criteria:  Patients aged 18 years and older Clinical diagnosis of mild/moderate idiopathic Carpal Tunnel Syndrome (paresthesias in the territory of the median nerve: in fingers 1, 2, 3 and radial border of 4 of the hand, nocturnal hand pain, and Positive Tinel's test, or Positive Phalen's test, or Positive Durkan's test) Diagnosis by electromyography and sensory and motor conduction velocity of mild/moderate involvement Patients who have agreed to participate in the study and signed the informed consent form.  Exclusion Criteria:  Cervical radiculopathy, polyneuropathy, brachial plexus pathologies, thoracic operculum syndrome Systemic diseases causing secondary Carpal Tunnel Syndrome (rheumatoid arthritis, diabetes with polyneuropathy, hypothyroidism with low adherence to treatment, chronic renal disease) Chronic corticosteroid therapy or regular use of non-steroidal anti-inflammatory drugs Severe carpal tunnel syndrome: signs of thenar atrophy, daytime pain, sensory deficit in median nerve territory (two-point discrimination test >10mm) Previous history of wrist or distal radius fracture Corticosteroid allergies Pregnancy - HealthyVolunteers: No - Gender: Female - MinimumAge: 18 Years - StdAgeList: Adult, Older Adult