Effect of Intravenous Nalbuphine and Magnesium Sulfate on Emergence Agitation in Pediatric
• Primary outcome: Measure The incidence of EA in children undergoing to hypospadias repair under general anesthesia is considered using Pediatric Anesthesia Emergence Delirium (PAED) scales.

• Secondary outcome:

Therefore, we designed a prospective, randomized, double-blind, single center study to investigate whether nalbuphine and/or magnesium sulphate can prevent EA after hypospadias repair in children under general anesthesia. In addition, the characteristics of anesthesia recovery and the incidence of adverse effects will also be evaluated in this study. Post-operative extubating time, interaction time, open eye time and emergence time. incidence of post-operative vomiting (PONV), laryngospasm, breath-holding, coughing, oxygen desaturation, and cardiac arrhythmias.
Face, Legs, Activity, Cry and Consola Bility (FLACC) scale is used to determine post-operative pain score
Parental satisfaction scores
- EligibilityCriteria: Inclusion Criteria:  • Weight: 10 - 38 kg.  Age: 3-7 years. ASA physical status: I-II. Operation: elective hypospadias repair under general anesthesia  Exclusion Criteria:  • Parent's refusal.  Anticipated difficult airway. Active respiratory illness (cough, fever, rhinorrhea) on the day of anesthesia. History of developmental delay or mental retardation or any neurological disease. Known hypersensitivity to any drug used in this study. Children with co-morbid conditions like congenital heart disease, respiratory pathology, central nervous system disorders or renal pathology - HealthyVolunteers: Accepts Healthy Volunteers - Gender: Male - GenderBased: Yes - GenderDescription: name of patient gender exposure on surgery only male participants are being due to surgery is hypospadias repair. - MinimumAge: 3 Years - MaximumAge: 7 Years - StdAgeList: Child