Effect of Inspiratory Muscle Training on Respiratory Functions and Exercise Capacity
In this study, we aimed to evaluate the effect of Anti- tumor necrosis factor (TNF) treatment on pulmonary functions in patients with AS and to evaluate the pulmonary functions and exercise performance of patients by adding inspiratory muscle training to spinal mobility exercises in patients with AS using Anti-TNF. We also aimed to investigate the relationship between these parameters and disease activity, spinal mobility and quality of life.
- EligibilityCriteria: Inclusion Criteria:  Patients diagnosed with ankylosing spondylitis according to the Modified New York Criteria Patients with BASDAI score <4.1 who received Anti-TNF therapy for at least 6 months Patients whose maximum inspiratory pressure value is <80% in the Pulmonary Function Test Patients who had a cardiac examination within the last year and no cardiac pathology was detected.  Exclusion Criteria:  The patient has a serious mental disorder Presence of neurological and pulmonary disease that would prevent the patient from using the PFT device Presence of uncontrolled hypertension Presence of uncontrolled diabetes Presence of uncontrolled cardiac arrhythmia Uncontrolled heart failure High-risk unstable angina and all acute cardiac diseases (acute myocardial infarction, acute endocarditis, myocarditis or pericarditis) Symptomatic severe aortic stenosis Acute pulmonary embolism or pulmonary infarction Severe pulmonary hypertension Presence of systemic infection or malignancy Pregnancy - HealthyVolunteers: No - Gender: All - MinimumAge: 18 Years - MaximumAge: 65 Years - StdAgeList: Adult, Older Adult