E-cigarettes as a Harm Reduction Strategy
E-cigarettes have emerged as an effective strategy for replacing cigarettes among smokers from the general population, but there is a dearth of studies investigating their utility in replacing cigarettes among smokers with opioid use disorder (OUD). This study aims to evaluate the feasibility and acceptability of implementing a cigarette harm reduction intervention involving e-cigarettes in office-based buprenorphine clinics.
- EligibilityCriteria: Inclusion Criteria:  Adult (age ≥21) Report smoking ≥ 5 cigarettes per day for ≥ one year Interested in switching to e-cigarettes (self-reported) OUD diagnosis (DSM-V)(chart review) Currently receiving buprenorphine or other medications for opioid use disorder (MOUD) (chart review) Plan to remain on buprenorphine for at least 3 months (duration of the study) (self-reported) Have a smartphone with internet access  Exclusion Criteria:  Use of other tobacco or nicotine products other than cigarettes (≥9 days in the past 30) Used nicotine replacement, bupropion or other pharmacotherapies as cessation aids in the past month (bupropion will be allowed for treatment of depression) (self-reported) (3) Having a severe medical condition, including decompensated cirrhosis, severe cardiovascular disease (myocardial infarction, percutaneous transluminal coronary angioplasty, unstable angina, coronary artery bypass graft, and/or serious arrhythmia in the prior 6 months) (chart review) Having severe asthma or chronic obstructive pulmonary disease requiring supplemental oxygen or hospitalization in the past 6 months (chart review) Being hospitalized for human immunodeficiency virus/acquired immunodeficiency syndromes-related illness in the past 6 months (chart review) Having a history of seizure disorder (chart review) Pregnancy (chart review) or breast-feeding (self-reported) for female participants Having current DSM-V criteria for mania, psychosis, or major depressive disorder (chart review) Current suicidal ideation or past year suicide attempt (PHQ-9; see protections against risk) Being hospitalized for psychiatric reasons in the past year (chart review) Being unable to independently read and/or comprehend the consent form or other study materials (unable to read study materials aloud) Being unable to read/speak English (inability to read and complete study materials) - HealthyVolunteers: Accepts Healthy Volunteers - Gender: All - MinimumAge: 21 Years - StdAgeList: Adult, Older Adult