Association Of Serum Vitamin D Level With Isthmic Spondylolysis
The aim of this study is to compare vitamin D level between young adults with isthmic spondylolysis and a matched healthy control group.
- EligibilityCriteria: Inclusion Criteria:  Patients: Adults aged 20 - 45 years with symptomatic isthmic spondylolysis Controls: Matched population without spondylolysis indicated for plain x-ray and CT lumbo-sacral spine. These will be recruited mainly from the Trauma Unit. This will not add any non-indicated radiation exposure to healthy individuals  Exclusion Criteria:  Traumatic spondylolysis Pregnant women Significant co-morbidities (renal or hepatic diseases, malignancy, malabsorption syndrome, musculoskeletal diseases, steroid therapy) Metabolic diseases affecting vitamin D and Calcium metabolism (e.g. hyperparathyroidism) - HealthyVolunteers: Accepts Healthy Volunteers - Gender: All - MinimumAge: 20 Years - MaximumAge: 45 Years - StdAgeList: Adult - StudyPopulation: Detailed history taking (including dietary calcium and vitamin D intakes, Exposure to sun, and Clothing habits)  Clinical examination Imaging: plain x-ray and CT scan Laboratory: Free serum calcium, alkaline phosphatase and 25-OH vitamin D - SamplingMethod: Non-Probability Sample