Oxytocin Rest to Reduce Cesarean Delivery
Prolonged labor is usually managed with continuous oxytocin infusion. "Oxytocin rest" has been proposed as a strategy to resolve protracted labor in patients who have received continuous oxytocin without progress. This strategy involves discontinuing oxytocin then restarting infusion after a period of time, under the theory that washout of the oxytocin receptor will strengthen uterine contractions to improve labor progress. "Oxytocin rest" is performed on labor and delivery units across the United States. Yet, there is no randomized or prospective data to support the practice.

The purpose of this study is to assess whether oxytocin rest of 60 minutes in patients with prolonged labor reduces risk for cesarean delivery.
- EligibilityCriteria: Inclusion Criteria:  ≥18 years of age Singleton gestation in vertex presentation ≥36 weeks gestation Prolonged latent labor, defined as cervical dilation <6cm after ≥8 hours since rupture of membranes and on continuous oxytocin  Exclusion Criteria:  Not meeting the above criteria Any contraindication to continuous oxytocin at time of randomization Cesarean section anticipated by the clinical team at time of randomization (for any reason excepting labor dystocia) >18 hours between rupture of membranes and randomization Known intraamniotic infection at randomization Fetal demise Any contraindication to vaginal delivery Maternal eclampsia - HealthyVolunteers: No - Gender: Female - MinimumAge: 18 Years - MaximumAge: 55 Years - StdAgeList: Adult