Stopping Pneumonia Antibiotherapy Regimen Early
The hypothesis for this trial is that an antibiotic strategy for the management of non-severe community-acquired alveolar pneumonia in children aged 3 to 59 months, including amoxicillin 80-100 mg/kg/day for at least 3 days in case of rapid response and 5 days in case of delayed response, would not be inferior to current French recommendations (antibiotic therapy for 5 days in case of rapid response and 7 days in case of delayed response) in terms of treatment of failure rate at 7 days.
- EligibilityCriteria: Inclusion Criteria:  Child with a diagnosis of community-acquired alveolar pneumonia defined as an association of 3 major criteria + at least 3/5 minor criteria:  Major criteria: Fever (> 38°C), Polypnea and Chest x-ray Minor criteria: Localized crackles, C-Reactive Protein (CRP) > 80mg/L, Alteration of general condition, Cough and Pulmonary condensation syndrome. Child with an episode that began less than 7 days before inclusion, in the community. Absence of hospitalization criteria  Exclusion Criteria:  Pre-existing underlying pathology: acquired or hereditary immune deficiencies, cardiac pathologies, chronic respiratory failure or pulmonary malformations, neurological or muscular diseases at risk of respiratory decompensation, serious chronic kidney diseases and nephrotic syndromes, sickle cell anemia, diabetes, chronic liver diseases, oncological pathologies and hematological, organ and hematopoietic stem cell transplants, inflammatory and/or autoimmune diseases receiving immunosuppressive treatment, people infected with HIV, obese people with a body mass index (BMI) ≥ the 97th percentile Wheezing during the episode Presence of pleural effusion on radiography Presence of toxin signs Antibiotic therapy within 48 hours before inclusion Anti-inflammatory therapy within 48 hours before inclusion Allergy or contraindication to penicillin History of more than 2 bacterial pneumonias per year Associated infection requiring more than 3 days of antibiotics Patient hospitalized within 15 days before inclusion Failure to obtain informed consent by the legal representative(s) Patient not affiliated with or not benefiting from a national health insurance scheme Patient participating in another interventional research involving human person - HealthyVolunteers: No - Gender: All - MinimumAge: 3 Months - MaximumAge: 59 Months - StdAgeList: Child