A Novel Conditioning Regimen for Myelodysplastic Syndrome With Moderate High IPSS-M Score
Figure out the Efficacy and Safety of Azacitidine Combined with BUCY2 Conditioning Regimen Before Allogeneic Hematopoietic Stem Cell Transplantation for Myelodysplastic Syndrome with Moderate High IPSS-M Score
- EligibilityCriteria: Inclusion Criteria:  Patients fully understand this study, voluntarily participate and sign the informed consent form Age equal or more than 18 years old Patients with moderate high-risk MDS with an IPSS-M score which is higher than 0 Patients planning to undergo allogeneic hematopoietic stem cell transplantation, HCT-CI ≤ 3 or KPS ≥ 80%  Exclusion Criteria:  Patients who refuse to participate in this clinical study Patients with central nervous system involvement Patients with HIV seropositive Patients with other serious medical conditions with a life expectancy of less than six months Patients with severe psychiatric or psychological disorders - HealthyVolunteers: No - Gender: All - MinimumAge: 18 Years - StdAgeList: Adult, Older Adult