Multimodality Imaging and Functional Lesion Assessment in Intermediate Coronary Stenosis in Chronic Coronary Syndrome
The aim of this prospective, investigator-initiated study is to evaluate the diagnostic accuracy and correlations between functional indices (fractional flow reserve, FFR) and morphometric indices: luminal and qualitative parameters assessed by optical coherence tomography (OCT) including minimal lumen area, plaque type, presence of thin cap fibroatheroma among patients with chronic coronary syndrome identified with intermediate grade coronary stenosis.
- EligibilityCriteria: Inclusion Criteria:  18 years or older Chronic coronary syndrome defined as presence of chest pain ranked 2-3 in the Canadian Cardiovascular Society classification or positive ischemia test (exercise test, single photon emission tomography (SPECT) Intermediate grade coronary stenosis of 40-80% assessed visually in coronary angiography FFR and OCT examination of the same lesion The patient is willing to participate in the study and has provided a written informed consent  Exclusion Criteria:  Acute coronary syndrome Proximal left main lesion Ostial right coronary artery lesion Bypass of the assessed vessel Contraindications for adenosine administration Hemodynamic instability Heart insufficiency in New York Heart Association (NYHA) class IV scale Acute renal insufficiency Pregnancy - HealthyVolunteers: No - Gender: All - MinimumAge: 18 Years - StdAgeList: Adult, Older Adult - StudyPopulation: Patients undergoing coronary angiogram due to chronic coronary syndrome with intermediate grade coronary stenosis. - SamplingMethod: Probability Sample