Development and Validation of the Prediction Model for Functional Mitral Regurgitation Regression in Heart Failure Patients Taking Guideline-directed Medical Therapy
This observational study is to develop and validate the prediction model for functional mitral regurgitation regression in heart failure patients taking GDMT. The patients diagnosed ≥2+ functional mitral regurgitation by ultrasonic cardiogram are enrolled in this study and would be clinically followed by at least one year (clinical visit at 3 months, 6 months, and 12 months), and then by when the endpoints are reached.
- EligibilityCriteria: Inclusion Criteria:  Age>18 years old ≥2+ FMR Receiving GDMT  Exclusion Criteria:  degenerative mitral regurgitation myocardial infarction, percutaneous coronary intervention, coronary bypass grafting surgery, cardiac resynchronization therapy, or stroke within three months prior to this study ≥2+ aortic stenosis or regurgitation previous surgical mitral valve repair or replacement restrictive cardiomyopthy, hypertrophic cardiomyopathy, or constrictive pericarditis severe heart failure (NYHA class IV) or left ventricular ejection fraction < 20% symptomatic hypotension affecting GDMT prescription severe hepatic or renal insufficiency life expectancy < 12 months Pregnancy - HealthyVolunteers: No - Gender: All - MinimumAge: 18 Years - StdAgeList: Adult, Older Adult - StudyPopulation: Chinese - SamplingMethod: Non-Probability Sample