Sleep Profile of Patients With Septo-optic Dysplasia
The aim of this study is to evaluate sleep of patients with septo-optic dysplasia compared to patients with an isolated disorder of peripheral visual system and patients with corpus callosum agenesis since both visus defict and agenesis of corpus callosum might be present SOD but associated to other features / structural and functional anomalies.

Included patients and their caregivers will be asked to compile standardize sleep questionnaires and a sleep screening through an interview will be scheduled. Patients will be asked to wear an actigraph on their non-dominant hand wrist for 7 days.
- EligibilityCriteria: Inclusion criteria group A:  diagnosis of SOD or SOD plus syndrome with or without a defined genetic diagnosis age 3-18 years availability of at least 2 serial sleep EEGs performed during clinical follow-up stable drug therapy in the last three months  Inclusion criteria group B:  diagnosis of congenital or early acquired isolated peripheral visual deficit with or without a known genetic diagnosis (e.g., congenital cataract, inherited retinal dystrophies, isolated eye maldevelopment). age 3-18 years grating or visual acuity < 3/10 availability of serial sleep EEGs performed during clinical follow-up stable drug therapy in the last three months  Inclusion criteria group C  isolated corpus callosum agenesis at brain MRI age 3-18 years availability of at least 2 serial sleep EEGs performed during clinical follow-up stable drug therapy in the last three months  Exclusion criteria group A:  absence of informed consent severe Intellectual disability and/or severe motor impairment melatonin assumption  Exclusion criteria group B:  absence of informed consent CNS involvement ( malformations/ lesions) severe Intellectual disability and/or severe motor impairment melatonin assumption  Exclusion criteria group C  absence of informed consent severe Intellectual disability and/or severe motor impairment melatonin assumption - HealthyVolunteers: No - Gender: All - MinimumAge: 3 Years - MaximumAge: 18 Years - StdAgeList: Child, Adult - StudyPopulation: Three groups of patients will be included:  Group A: 15 patients with septo-optic dysplasia Group B: 15 patients with disorder of peripheral visual system Group C: 15 patients with Corpus Callosum agenesis - SamplingMethod: Non-Probability Sample