Potential Correlation Between Heart Rate Variability With Cardiovascular Risk at Different Stages of Metabolic Syndrome
The study aims to assess the beat-to-beat Heart rate variability (HRV) in different stages of metabolic diseases, including pre-diabetic and diabetic patients, compared to non-diabetic individuals.

Heart rate variability will be compared for some antidiabetic drugs used in different stages of metabolic diseases and correlated to different metabolic and inflammatory mediators.
- EligibilityCriteria: Inclusion Criteria:  Non-diabetic individuals: adults (18-70 Years) with glycated hemoglobin (HBA1C)<5.7 and/or Fasting blood glucose <100 mg/L and with no classic symptoms of hyperglycemia  Pre-diabetic: adults (18-70 Years) who fulfil one of the American Diabetes Association (ADA) criteria :  glycated hemoglobin (HBA1C) =5.7-6.4% Fasting blood glucose level = 100 mg/dL to 125 mg/dL. Fasting is deﬁned as no caloric intake for at least 8 hours.  Diabetic patients: adults (18-70 Years) who fulfil one of the American Diabetes Association (ADA) criteria:  glycated hemoglobin (HBA1C) ≥6.5% Fasting blood glucose ≥126 mg/dL. A random plasma glucose ≥200 mg/dL. Random is any time of the day without regard to the meals.  Exclusion Criteria:  Pediatric and elderly subjects Pregnant subjects Those with active Myocardial infarction Those with acute decompensated heart failure Patients with pacemaker Patients with persistent Atrial fibrillation, long-standing persistent and permanent Atrial fibrillation - HealthyVolunteers: Accepts Healthy Volunteers - Gender: All - MinimumAge: 18 Years - MaximumAge: 70 Years - StdAgeList: Adult, Older Adult - StudyPopulation: patients aged 18-70 Years either diabetic, pre-diabetic or non-diabetic should not have one of the following criteria:  Pediatric and elderly subjects Pregnant subjects Those with active Myocardial infarction Those with acute decompensated heart failure Patients with pacemaker Patients with persistent Atrial fibrillation, long-standing persistent and permanent Atrial fibrillation Amputated patients - SamplingMethod: Non-Probability Sample