Phenotypic and Genotypic Characterization of Patients With Dysmetabolism in Greenland
The goal of this clinical trial is to perform a detailed description of the feno- and genotype of people living with type 2 diabetes and severe obesity who are linked to care at Steno Diabetes Center Greenland.

The main questions it aims to answer are:

Are monogenetic diabetes variants associated with the same risk of developing late diabetic complications as other types of diabetes?
Can genotyping and thereby personalized medicine be implemented in Greenland, and can personalized medicine lead to improved treatment?
What is the prevalence of sleep apnea among high-risk individuals in Greenland?
Is it possible to develop and implement a simple algorithm for the identification of sleep apnea in Greenland that can ensure treatment of severe sleep apnea?

Participants will:

Answer WHO-5 and FOSQ-10 questionnaires regarding quality of life and functional outcomes of sleepiness
Perform VAGUS examinations for Cardiovasculare Autonomic Neuropathy
Clinical examination of height, weight, circumference of hip, waist and neck, Friedman tonsil and tongue score, nasal air flow, nasal septal deviation
Blood samples for full genome sequencing
- EligibilityCriteria: Inclusion Criteria:  Type 2 diabetes and/or morbid obesity (BMI >40) Over 18 years old  Exclusion Criteria:  Does not speak either English, Danish or Greenlandic - HealthyVolunteers: No - Gender: All - MinimumAge: 18 Years - StdAgeList: Adult, Older Adult