YOD-RiSoCo: Social Cognition and Risky Decision-making in Patients With Young-onset Dementia
The goal of this observational study is to learn about social cognition and risky behaviour in patients with young-onset dementia (YOD). The investigators want to

Examine differences in performance on social cognition test and measures of risky behaviour between behavioural variant YOD patients, patients with frontal brain injury, non-behavioural YOD patients and healthy controls.
Examine if there is a relation between social cognition tests and measures of risky behaviour.

Participants will be administered a neuropsychological assessment including social cognition measures and patients will complete a driving simulator task in which risky behaviour will be elicited.
- EligibilityCriteria: Inclusion Criteria:  All subjects  Sufficient command of the Dutch language In possession of a driver's license with any driving experience throughout life Age 18 to 65  bvYOD subjects  Probable diagnosis of young-onset dementia (before 65 years old), confirmed after interdisciplinary consensus meeting in which interviews, neuropsychological examination, neurological and psychiatric assessments, neuro-imaging, blood samples, and in some cases FDG/PIB-PETscans, CSF biomarkers or genetic counseling were discussed. Nosological diagnosis of bvFTD or bvAD  Non-bvYOD subjects  Probable diagnosis of young-onset dementia (before 65 years old), confirmed after interdisciplinary consensus meeting in which interviews, neuropsychological examination, neurological and psychiatric assessments, neuro-imaging, blood samples, and in some cases FDG/PIB-PETscans, CSF biomarkers or genetic counseling were discussed. YOD subtypes other dan bvFTD or bvAD, such as amnestic variant AD.  Frontal brain injury subjects  - Neurological patients with frontal brain injury (e.g. traumatic brain injury, stroke or brain tumor patients).  Exclusion Criteria:  All subjects  Suffering from severe motion sickness; motion sickness is a risk factor for simulator sickness  YOD subjects:  - Presence of premorbid severe neurological or psychiatric pathology, non-related to dementia.  Frontal brain injury subjects:  - Presence of serious psychiatric disorders or other neurological comorbidities.  Healthy control subjects:  Presence of serious psychiatric disorders History of neurological disorders, which may interfere with cognitive functioning (e.g. recent concussion, previous subarachnoid or intracerebral haemorrhage, intracranial tumours, epilepsy, ischemic stroke). - HealthyVolunteers: Accepts Healthy Volunteers - Gender: All - MinimumAge: 18 Years - MaximumAge: 70 Years - StdAgeList: Adult, Older Adult - StudyPopulation: Patients with young-onset dementia, i.e. onset of dementia before the age of 65 years. - SamplingMethod: Probability Sample