Renal Doppler to Predict Acute Kidney Injury (AKI) in ARDS Patients. (RED-AKI Study)
This is a multicenter international observational prospective cohort study. The main questions it aims to answer are:

PRIMARY AIM: To describe the capability of IRVF demodulation at diagnosis of ARDS to predict development of AKI within 7 days from the ARDS onset
SECONDARY AIMS: A)Describe the capability of IRVF demodulation or pattern of IRVF (continuous, pulsatility, biphasic, monophasic) to predict development of AKI within 14 days from the ARDS onset. B) To describe the RD parameters and VexUS in the AKI and no AKI patients over time. C) Describe the impact of invasive mechanical ventilation (IMV) on the intrarenal venous congestion and VexUS., D) Evaluation of effect of CRRT on IRVF pattern, VexUS and parameters. E) Describe the feasibility of renal doppler to assess IRVF in critically ill respiratory patients. F) Evaluate the incidence of AKD and CKD Participants will Adult patients with diagnosis of ARDS admitted to intensive care unit and undergoing invasive mechanical ventilation
- EligibilityCriteria: Inclusion Criteria:  Age > 18 years Critically ill patients admitted to intensive care unit with a diagnosis of ARDS according to Berlino criteria Beginning of IMV less than 48 hours or Clinical decision to begin IMV. Life expectancy > 24 hours Informed consent signed  Exclusion Criteria:  No patient will be excluded from the study because of gender, race, ethnicity, or sexual preference.  AKI prior to the onset of ARDS Chronic respiratory failure due to chronic respiratory diseases Chronic renal disease (CKD stage ≥ 2) and any ureteral obstruction. Definition of CKD patient is according to the latest guideline KDIGO Chronic Heart Failure Chronic liver disease Major trauma in the past 3 months Major surgery in the past 3 months Smoking and Alcohol drinking BMI ≥ 35 Patients needing of VV-ECMO and VA-ECMO Beginning of positive pressure ventilation more than 48 hours (invasive or no invasive) Life expectancy <24 hours Cardio Circulatory Arrest Neoplasm in chemotherapy/radiotherapy Do Not Resuscitate or Comfort Measures Pregnancy at ICU admission Refused Informed Consent by the patient or surrogate decision-maker - HealthyVolunteers: No - Gender: All - MinimumAge: 18 Years - MaximumAge: 80 Years - StdAgeList: Adult, Older Adult - StudyPopulation: Adult patients with diagnosis of ARDS admitted to intensive care unit and undergoing invasive mechanical ventilation (IMV). - SamplingMethod: Probability Sample