The stupid Duryodhana did not accept the constant advice of Yudhishthira viz. do not fight, which was like the wholesome drug.
युधिष्ठिरस्य वचनं मा युध्यस्वेति सर्वदा॥ दुर्योधन नाभ्यगृह्णानमूढः पथ्यमिवौषधम्।