Disease, contact with painful things, toil and want of objects desired, these are the four causes of the sufferings of the body.
व्याधेरनिष्टसंस्पर्शाच्छ्रमादिष्टविर्वजनात्। दुःखं चतुर्भिः शारीरं कारणैः सम्प्रवर्तते॥