What is botox?
user
Botulinum toxin type A (botulinum toxin A) is a neurotoxic protein produced by the bacterium Clostridium botulinum.  It inhibits acetylcholine release by acting on nicotinic acetylcholine receptors, and is used in medicine for its muscle-relaxing effect.
assistant
How do they use it medicine?
user
Botulinum toxin has been used since the 1970s to treat neuromuscular disorders, by injecting it into the affected muscles. It is considered a safe and effective treatment for a variety of muscle-related disorders, including facial wrinkles, cervical dystonia, and chronic migraines.
assistant
I have heard of it for wrinkles and migraines. Are you sure it has been around since the 1970's though? That seems early.
user
Some early medical uses of the toxin pre-date this. The use of botulinum toxin for cosmetic reasons may be most commonly traced back to 1989, but medical applications are significantly older.
assistant
What is botox?
user
Botulinum toxin type A (botulinum toxin A) is a neurotoxic protein produced by the bacterium Clostridium botulinum.  It inhibits acetylcholine release by acting on nicotinic acetylcholine receptors, and is used in medicine for its muscle-relaxing effect.
assistant
How do they use it medicine?
user
Botulinum toxin has been used since the 1970s to treat neuromuscular disorders, by injecting it into the affected muscles. It is considered a safe and effective treatment for a variety of muscle-related disorders, including facial wrinkles, cervical dystonia, and chronic migraines.
assistant
I have heard of it for wrinkles and migraines. Are you sure it has been around since the 1970's though? That seems early.
user
Yeah, that’s weird, I don’t have a clear source for that, but it is an early use of the protein.  Let’s try to think about it another way.  I could tell you more about the molecule that causes botulism, and the use of neurotoxins like this to treat brain diseases.  Then maybe that will explain it to you?
assistant
What is botox?